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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
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                <person name="Boedeker C."/>
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                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
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                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
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                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">Mal33</strain>
        </source>
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            <dbReference type="EMBL" id="QDV54152.1"/>
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</entry>
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                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
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                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
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                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
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                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
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                <person name="Devos D.P."/>
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                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.3.-" evidence="1"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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            <dbReference type="EMBL" id="QDV54145.1"/>
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    <sequence length="214" mass="23787" checksum="49819986040A1057" modified="2019-10-16" version="1">MLTSTFVYFDLGNVLVKFDPELACRQVGDLLECDPTTIRAAMYDSGIEELLESGQIEEPEFLDRLFSSVGRSAAGDAVLEAMSAMFRLNTPILPVVSRLVSEGVPMGILSNTCRPHWDWIMRQNYGLLRQNYGLLRLIGTPAALSYEIGCMKPDPKIYHAAAELAGCAAEQILFIDDRIENVQGATACGWRAIHYIDTPTLIEDLRAMGYRCFV</sequence>
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
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                <person name="Storesund J.E."/>
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                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
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                <person name="Mueller R.-W."/>
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                <person name="Spormann A.M."/>
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                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="entry name" value="TPR-like_helical_dom_sf"/>
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        <location>
            <begin position="748"/>
            <end position="1035"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1046" mass="114754" checksum="3185BD8EF12F2713" modified="2019-10-16" version="1"> </sequence>
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<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.99.28" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047061">
        <property type="term" value="F:glucose-fructose oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GFO_IDH_MocA" evidence="1">
        <location>
            <begin position="6"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="372" mass="41394" checksum="A2CB8E5A3B4966D3" modified="2019-10-16" version="1">MNGKVNGAMIGLGFGAEFLPIYAAHPQANIGAICRRNAAELEKTGNQFGIEKRYTDYDAVLADPEIDFVHINSPIPDHAWMTLKALDAGKHVMCTVPMATTIEDCQKIVEKVKATGLKYMMAETVVYSREYLFIKEMFTKGELGKIQHLAASHPQDMDGWPSYWEQMIPMHYATHAVSPCLGLVDGLAEYVSCFGSGTVRDDIAEKSGNKFAVESCHIKVKDSDLTAHIWRFLYDVARQYRESFDVYGTKKSFEWTLVENEPHVLHTAKKPEPEIAEKVEVPDFAHLLPAEIQKFTQPAEIHDSEHLSFIQGGGHGGSHPHLVHEFVSALKEDRDPMPNAVTSANWTCVGICAHQSALRGGEIVRLPEFTLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IM99</accession>
    <name>A0A518IM99_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cytidylate kinase</fullName>
            <ecNumber evidence="2">2.7.4.25</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">cmk_1</name>
        <name evidence="2" type="ORF">Mal33_01530</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.4.25" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="458"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="509" mass="56244" checksum="C9898A983C223CAF" modified="2019-10-16" version="1">MQADSSGTNPDLIDALRSAEVYDDASGPPQEIQTHISFLFLTDAHVYKLKKPVDFGFLDYSTLAKRRAACQAEVELNRRLAADTYLGVVPVGRGTDGSWRIGDGVEPVEWLVKMRRLPDERCLTQMIQRDDWGDRDIAPIVAMLSGFYRGLSPVPMPNYAACYRQHVVDNGRELLDEKHRLPRALVQRVQAAQLQFMFLYGDALLQQRAADGHVVEGHGDLRAEHIYWTQPPVAIDCIEFSRELRLVDTADELSFFAMTCDDAGVPELGEAVLRRCCQALGDVPDLLLVAFYRCYRACVRAKVEALRTDQTTGTSGPDSQPGAVRLIELADRYAQQLVSPTAVIVRGLSGTGKTTVAKALAERMGAVHLSTDALRKANSPDDDVNYDAESRQQVYNTMFDQAVGHLQNRVPVVVDGTFLQADLLREAQQRLAAAGDKVVVATCICPEEVAIDRIRQRQRRSDSLSDADETVYRQQVAQADRGSPGMAGIKVDTTADMPAILEGIRRGLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMB6</accession>
    <name>A0A518IMB6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CYTH domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_01760</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd07890">
        <property type="entry name" value="CYTH-like_AC_IV-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008173">
        <property type="entry name" value="Adenylyl_cyclase_CyaB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033469">
        <property type="entry name" value="CYTH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023577">
        <property type="entry name" value="CYTH_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21028">
        <property type="entry name" value="PTHR21028"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01928">
        <property type="entry name" value="CYTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01118">
        <property type="entry name" value="CYTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55154">
        <property type="entry name" value="SSF55154"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00318">
        <property type="entry name" value="cyaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51707">
        <property type="entry name" value="CYTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CYTH" evidence="1">
        <location>
            <begin position="3"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="187" mass="21104" checksum="239527667BE137D6" modified="2019-10-16" version="1">MSQYEVELKFPVADLAALRRQLIDRGARPLGIQQHRDTYYNHPCRDFAETHEALRIRRVDDQPMITYKGAKLDSPVKTRIELEWALGAGDVDGSNTEAMLVHLGFRRVAEVAKQRESFAVQPEAPSSELTVTLDDVQRVGTFAEIECIAEADGIERAQEYVQAFAESLGLQNPEKRSYLRMLLQADG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMD8</accession>
    <name>A0A518IMD8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Biofilm dispersion protein BdlA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">bdlA</name>
        <name evidence="5" type="ORF">Mal33_02010</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004089">
        <property type="entry name" value="MCPsignal_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00015">
        <property type="entry name" value="MCPsignal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00283">
        <property type="entry name" value="MA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50111">
        <property type="entry name" value="CHEMOTAXIS_TRANSDUC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0807">Transducer</keyword>
    <feature type="domain" description="PAS" evidence="3">
        <location>
            <begin position="33"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="4">
        <location>
            <begin position="106"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="4">
        <location>
            <begin position="222"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="domain" description="Methyl-accepting transducer" evidence="2">
        <location>
            <begin position="263"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV54251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="445" mass="48848" checksum="E376E7295A905E09" modified="2019-10-16" version="1">MWNNRIFAAHEANDISVAVLDQATEAVESEPSSHSQIYSALDRSQAIIEFDPTGKILTANKNFLNCLGYTIEEIRGQHHRIFVAPHYADSAEYKDFWNALANGEFQSSEYQRFGKNHKEIWIQATYNPVRDQAGKVYKVVKFAVDISAKRLAAIDAINKTQACIEFRPDGTILTANPRFCDAMGYSLDEIRGHHHRMFCDPEWTKSNDYVAFWNALSRGQFQQDEYKRFAKGKREIWLQATYNPVFDAKGNVEKVVKYATDISHQMENKRQASEVGSSIAASVTEMAQAIDEISQNIAQTATLAQTATTDANAATQCVEELNSNSKSIGKVVGVIQDLAEQTNLLALNATIEAARAGEAGRGFAVVATEVKQLATQTAKATNSIETNVADIQSNIEQVVRSIKGIADGVSEVSTNTTTAAAAVEEQSVLMSGLSSTAQKLLSMNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMF0</accession>
    <name>A0A518IMF0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_02200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045301">
        <property type="term" value="F:tRNA-(2-methylthio-N-6-(cis-hydroxy)isopentenyl adenosine)-hydroxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07910">
        <property type="entry name" value="MiaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010386">
        <property type="entry name" value="tRNA-Hydrxlase_MiaE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42637">
        <property type="entry name" value="PTHR42637"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06175">
        <property type="entry name" value="MiaE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF020736">
        <property type="entry name" value="MiaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="228" mass="25996" checksum="4B45A86FDB0A2293" modified="2019-10-16" version="1">MTPQYSAKRYSLNATSLGSSATGCRASPLHFPDHGFFMLRLKSNSSQRWLSQVESNLDEILIDHAHCERKAASTAMGLMNSYAERRELCDEMASIVIEELEHYRMVLDVLDSRGIRFRQLKPSPYGSQLNALIIRTEPQRAVDKLLVASLIEARSCERFDLLRKHAPDKVLADFYDSLFESEARHHATYVRLAEEFAPRAEVQRRLNELSEAEAKIIEVGSELARMHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMI2</accession>
    <name>A0A518IMI2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Response regulator PleD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">pleD_2</name>
        <name evidence="4" type="ORF">Mal33_02520</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="3">
        <location>
            <begin position="163"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="98"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV54302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="307" mass="34014" checksum="01B927FF840E531A" modified="2019-10-16" version="1">MPLSQSMIFLTGVGVGAFLFALGIWGGFGWGRRRGRRDATAPLQGAELLGIIEALSRWTSEYSGNVTRYQDELSSAARVVQETIETGNPKTTPIVKVLDDIMTSNQSLKQRLDDAERQLEKQTRSIEAYISEARTDALTKLPNRRAADQRLDEMFSAWQKGGPGFVVAMIDVDHFKQINDRYGHPEGDAVLQHMAQLLTNHIEGAYMVARFGGEEFVALMPPPLRVAADRLDRFRKIVAEQSVIVGDQEIEFTISVGVAECRNDLLVGPIVRRADEALYAAKGMGRNRVYFHDGKQPILVGAPEIAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMK2</accession>
    <name>A0A518IMK2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_02690</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="184"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="192"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="304" mass="34490" checksum="5D06BE2BDA6230BA" modified="2019-10-16" version="1">MASFPIYKVSSLDSEDLEQLGTKPKYWYHDGDRRMMFKAENRQTGEDWAERIACEICQELGLPHVHYELAFDTHQNLPGVICQNIAAKPRSLILGNQLLLEVDPAYPSDEEKHYSVQEHTVDAVWEVVSKLAPPDQIASVPHEASSAGAVFIGYTILDALIANQDRHHQNWGAVRGDTTQLAPTFDHGAGLARNETDLKRRRRLDAGDSQRQMEVYTSRARSAFFRNSQDTRTITTYDAAEAFSQQNTQAATTWLQRLQHLSPHKLSDIVNRVPESRISPTAREFTIRLLEINRTRLLNLIATL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMU0</accession>
    <name>A0A518IMU0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alkaline phosphatase synthesis transcriptional regulatory protein PhoP</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">phoP_2</name>
        <name evidence="3" type="ORF">Mal33_03610</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="16"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="134" mass="14856" checksum="7A2515685DA96EAF" modified="2019-10-16" version="1">MTDPAAETQSQADAPKILIVDDDNEIVDSIRYALEANGYQVVVARDGNQGLALAERENPQLMILDMMMPKRSGFLVLEKLRRVREEPLPVVMITGNEGSRHKAYAELLGVSDYIRKPFAMDKLIASVANLLAQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IN70</accession>
    <name>A0A518IN70_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Spore coat protein SA</fullName>
            <ecNumber evidence="3">2.4.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">cotSA</name>
        <name evidence="3" type="ORF">Mal33_04770</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.4.-.-" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13579">
        <property type="entry name" value="Glyco_trans_4_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0167">Capsid protein</keyword>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0946">Virion</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="32"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="196"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="391" mass="42739" checksum="34E3751C58599416" modified="2019-10-16" version="1">MRVAHVITRMIVGGAQENTLFNCLDLQRIYGDDVILITGPSLGPEGDLLQQGRAEGLKVIVLPDLVRAIDPVRDWKALRAIRQTLRDFQPDVVHTHSAKGGILGRQAAHDLGVPAILHTVHGAPFHPYQSPPVRWFYKACEKRAAGQCHRLISVADAMTRLLTDAGVVAAPKCTTVYSGMNVDPFLWADTHRLAVRQRLGIGDDEVVVGKIARLFHLKGHADLIQAATTVVKAHANVKFLLIGDGILRDELTDQIRQAGLEDRFCFTGLVPPEDIPEYLGAMDLLVHTSYREGLARALPQALIAGKPVISYAIDGAPEVVIDGETGFLVSAGDIDRLADRIVELVGDKKMRADLGGQGRARFTDAFRHETMTSRLREIYQQILADSAGGDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INA7</accession>
    <name>A0A518INA7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_05380</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="111" mass="11740" checksum="769403EA03578F1E" modified="2019-10-16" version="1">MPETGLVEGTVTMDGQPLPNVSIVFQPQDDPKARASMALSDEQGHYSLSYHADKQGALIGPHKVSVTTPSDAPDPSGQAKEPIPAKYNSKSELVVEVQAGSNDIPLELTSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INB4</accession>
    <name>A0A518INB4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PSCyt2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_05070</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011444">
        <property type="entry name" value="DUF1549"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07583">
        <property type="entry name" value="PSCyt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="66"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="PSCyt2" evidence="3">
        <location>
            <begin position="197"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="592"/>
            <end position="611"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV54552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="697" mass="75276" checksum="33C3B36887879E04" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INL0</accession>
    <name>A0A518INL0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AAA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_06350</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="2">
        <location>
            <begin position="232"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="502" mass="57142" checksum="C9F65112CB0DE686" modified="2019-10-16" version="1">MVPTAKQQGSDSKLDALLAKIHGLSDGMGRQPTPQAEPMDAELVTPEKPVVAIRPQPVPRTEAVVAAQPARPAEASSFEPCRDEPWRPSEVRSLSESRISETLLEQITMRFLLNAGEADGREIAEQLKLPFGLVEPGLNRMKMEQTVAYRSSTATGDYLYVLTESGRDLARRYVEDCTYYGACPVLLSEYVDSVRRQTVEGQRPQKTDLLKAFSDLLINPRMLERLGPAINSGRGMFLFGYPGNGKTSIAERVTAAFGKYIWIPRSIFIDGEIMRVYDPMNHDLAMPESGGGLLSDSAFDRRWVRIKRPTIIAGGELTMDMLEVRRNPDSNISEASMQLKSNCGTLVIDDFGRQRMRVDELLNRWIIPLEKRYDFLNMASGKKIQVPFDQLVIFSTNLEPKDLVDDAFLRRIPYKIEVTNPSEADFRKLFEIMCKVTKIPYQPEPIDYLIKNHYLPVNRPFRNCQPRDLLLQVRNYCMYHGKPIELCNEYFDFAVENYFSVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INT6</accession>
    <name>A0A518INT6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_06820</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033234">
        <property type="term" value="P:negative regulation of protein sumoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="FSCB"/>
    </dbReference>
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        <property type="entry name" value="PTHR36135"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
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    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="14"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="315"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="730"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="315"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="394"/>
            <end position="558"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV54722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="880" mass="97610" checksum="0AA691048FAB51B5" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INX7</accession>
    <name>A0A518INX7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Trehalose utilization</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_07600</name>
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            <taxon>Planctomycetia</taxon>
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    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
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        <property type="entry name" value="ThuA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06283">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021764428" evidence="1">
        <location>
            <begin position="25"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="domain" description="ThuA" evidence="2">
        <location>
            <begin position="36"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="255" mass="28046" checksum="0048EA18EEE81886" modified="2019-10-16" version="1" precursor="true">MLNRANLFCLAVSFTLASLGGLRADDAKPAAARSINVLLVTGGCCHDYDFQAKAIQLAAAERGLKVQWTVVNDGGTGTTAEIDLYKNVDWSQGFDVVIHNECFANTTDPDYIRSITDPHKAGVNAVVIHCAMHTYRAADVDDWREFLGVTSRKHEHKSNYPVKVVKPEHPIMAGFPSDYKSETDELYVIEKIWPGTTILATSTSEKTGKEHGVYWTNQYGKARVFGTTYGHSNETFGDPVFLDTLIKGLAWAAGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP78</accession>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
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    </protein>
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        <name evidence="2" type="ORF">Mal33_08710</name>
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    <organism evidence="2 3">
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        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Rosistilla</taxon>
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    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="103" mass="11331" checksum="B76D3C70F0E56799" modified="2019-10-16" version="1">MIRLPPEEKQQTPEQEHSQKLAEVAGLVARGLDPTEAAGIVNVDIAGQQLPRKSSFMPSPDEIAAQCLAVQAGWSPQERVRRQRGLVERYGIPLVRCADIGFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP89</accession>
    <name>A0A518IP89_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_08770</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetes</taxon>
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            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="82" mass="9113" checksum="36AC0D49D5106C25" modified="2019-10-16" version="1">MRLAYGLFLASACGFIRADEPAVYATDDAKPEVVLEDAPTRIEEAMKRLGGRTKKLDDKLAVIQAAYSEGDTRRRNKNNRLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPH8</accession>
    <name>A0A518IPH8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Biopolymer transport protein ExbB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">exbB_2</name>
        <name evidence="9" type="ORF">Mal33_09610</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the exbB/tolQ family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002898">
        <property type="entry name" value="MotA_ExbB_proton_chnl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01618">
        <property type="entry name" value="MotA_ExbB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="96"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="196"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="237"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="MotA_ExbB" evidence="8">
        <location>
            <begin position="154"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV54993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="293" mass="31051" checksum="4424FB7C66A397E3" modified="2019-10-16" version="1">MTRLSNLNDAKRPALGLFGWCFIALAFSMFALITPAVAQDDAADEFADAPAEPAAAAPAEPAAEAAAPAGGAAPVDAAPDASDQSLLGWVYQSLGLTYLLVFLALSFTFVSLLVMNLLTARRDTLCPQELVDSFEEKLDSKDFQQAYDLARSDESVLGHVLSAGLAKLSKGYNKALEGMQEVGEEESMKLEHRLSYMALIGNISPMIGLFGTVDGMIRSFQVIATSGSTPKPSELAGGISTALFTTLVGLAIAIPAIAAYNILRNRVTRLLLEVGVTSEDLMSRFEDIKPGAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPU4</accession>
    <name>A0A518IPU4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_10660</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="238" mass="26736" checksum="50D7058F5BAE47D5" modified="2019-10-16" version="1">MFIDRFAAASGEAVCRLPLGDPWEVAEEHFYPWNTIDIVPDSPVRLPLVGYGSLMNRSSARRTLSEQSVSSARPVLVMGARRVYEYVMSPRGRQIYGEQEAEGRFGVLNARSSNDSNDWFNGIQYELDAVDIMALVERESAYDLLPAWTIPWDAKDSAPQIGYFLSCRTESHEGRQLLDSQLLPHPNYHAICEEGCRDVSSDFLKAFRRSTWVREARVSDVAETLACDATTPPPASQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPX8</accession>
    <name>A0A518IPX8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_11030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="169" mass="18807" checksum="B3369FE128AC105D" modified="2019-10-16" version="1">MSELDLKAAALRQTSEQSFQQLKIDSATCRGFLLIADRGSCGSRRRLRRMRSLREPRLGATHVGNLSPPPGLFVDCRSRILRLAPQALCDRRLRGFCRVRGAKLRSFASFRPIGASRASGVSAWGTCPQHATVGRLVVNCACPQFIGSVWFAEVRLLERRKLLARLVIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPY9</accession>
    <name>A0A518IPY9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_11300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="171" mass="19188" checksum="0856EE0FEAF8DDD4" modified="2019-10-16" version="1">MKPRTSITTFVVMLMLCSVGNALGPYSIDRLKRESDIAVICTVQSSSIVPNDSGYGPETTEMFRTRIRPIVYTHGTATETELVVRHFGVKHNHGKGTGGKARRYIRFVGPSETESETSFLPGPDQFYMMYLKRDGDEFVPTSGQRDARDSIIPLQLTRNQARIQRQTKNDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQ36</accession>
    <name>A0A518IQ36_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Thiol-disulfide oxidoreductase ResA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">resA_2</name>
        <name evidence="3" type="ORF">Mal33_11710</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016209">
        <property type="term" value="F:antioxidant activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019207">
        <property type="entry name" value="DUF2092"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09865">
        <property type="entry name" value="DUF2092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021803161" evidence="1">
        <location>
            <begin position="24"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="2">
        <location>
            <begin position="271"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="423" mass="45517" checksum="4058A7D857CC8B35" modified="2019-10-16" version="1" precursor="true">MFTRHLAPALAGLFAIAASSLSAQEPAKVSPEAAPVLSAFVDQIKAAKAVTAVFKTSEQVFSEGQVVFETKTDYSAASALPNKFALRVDSEELNVDIISDGKMLNMLVTPDAYISKDSPATLADLIVEPGMPGGPIIDALLAMTIPSESARESLLTDVTSVELVKPEGDAKPAGKTLQLNRADDSFVQLTITDGKQPKLAGMLIDMTELIKRANPQVQKTPGFKFVVNVVVEKWEWAEGGPDTFKFEAPKDAKAFASVEALVESMEGGPHPLVGKPAPDFEAPLMDDSTLKLSKHLGKDVVILDFWATWCGPCRLAMPVISEVAEEFKDKGVVLYAINNAESKAEIEAFLKQSKLAITVARDEDSSIAMTYQVTGFPMTVMIGKSGKVENVHLGFQSLENLREQLTTELSVLSKGESLVESKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQA8</accession>
    <name>A0A518IQA8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Agmatine deiminase</fullName>
            <ecNumber evidence="2">3.5.3.12</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">aguA_2</name>
        <name evidence="2" type="ORF">Mal33_12130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.5.3.12" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047632">
        <property type="term" value="F:agmatine deiminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004668">
        <property type="term" value="F:protein-arginine deiminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009446">
        <property type="term" value="P:putrescine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007466">
        <property type="entry name" value="Peptidyl-Arg-deiminase_porph"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31377">
        <property type="entry name" value="PTHR31377"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04371">
        <property type="entry name" value="PAD_porph"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="343" mass="37767" checksum="BB5FF66375F55BCB" modified="2019-10-16" version="1">MTQPLSSVRWPAEWEPQDALWLSWPHNRETWPGLYEPVPKAFANLARQIALATPVRVLAGSAVAAEADQVLRGISNLELVDVETNDCWIRDYGPTFVHAADGSLAGVDWRYNSWGGKYPPWDRDAAAAEKILKQIGVKRIPSTLCLEGGAIETDGAGRLLLTPDCVLTDTRNPGCDKAQVEAELSEKLGVREFIWLTGGGLIGDDTDGHIDQLARFVDPENLVIASCEPSDPNYPALEANYQQLVRWADEAEGNIQIHRLPIPAPRDVDGQRVPECYCNFLISGPQVLVPTFADPESDRRAVAILRNLMPQHDVVPLNASSLSWGLGAFHCMSQQQPRPQVPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQL8</accession>
    <name>A0A518IQL8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_13550</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021762535" evidence="1">
        <location>
            <begin position="25"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="260" mass="27785" checksum="F7A2ED4E30F89E0F" modified="2019-10-16" version="1" precursor="true">MKRIFNQTTITMAMTMAITCFAIAEGARGASPAEQAIRAAGSNNQFVFVMFYRGNDAATKTMHGTLQTALANRQDAVVVPVQIGDVSEQALVKQFDATRMPMPATVTLAPNGAVCSVFPRRITAPQVVAAIVSPGQTQILKALQDRKLVLLCAQPNADTSVPLGVRQFQSDALYNSRTEIVTVLLDDPAEAEFLTKIGVKPGQPTPVVAFMAPPGVMVGIFKDSVSFNVLAEKLATAGKCCDDENCKHHKSAQAPQPARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQM7</accession>
    <name>A0A518IQM7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Archaeal TRASH domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_13680</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011017">
        <property type="entry name" value="TRASH_dom"/>
    </dbReference>
    <dbReference type="SMART" id="SM00746">
        <property type="entry name" value="TRASH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022077451" evidence="1">
        <location>
            <begin position="22"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="domain" description="TRASH" evidence="2">
        <location>
            <begin position="171"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="domain" description="TRASH" evidence="2">
        <location>
            <begin position="238"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="TRASH" evidence="2">
        <location>
            <begin position="321"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="459" mass="47714" checksum="B9C6FC51AFA24221" modified="2019-10-16" version="1" precursor="true">MKRTLIITAFSLAMSTSGVFGQTIQSQHNHTGHNHAMPGMTQAREATQAGPHGGSLKQTGNLQIETIVSQGGLQMFVYDRAGQPVSVDQGRGAVSVRVEGNAKRYRYDLLPDGKGALTAPVNLSQIAGRQIDVDVQLVGIVASTISFNEVATVPASEQQLAAAAIARQKICPVSGKPLGSMGDPVAVDVNGQKLYVCCAGCVNAVKSDPAKYAAGRPQITVTTATQADAAAIAAQKVCPVMDEPLGGMGTPIKVMVGDKPIYLCCKGCIKKIQAEPAKYLAMVYGNGPQNSGQPAVTTAAKITVSTSTQADAAAIAAQKVCPVMDEPLGGMGTPIKVMVGDKPIYLCCKGCIKKIQAEPAKYLAMVYGNGDQASVPAGTEQVRDGIFKVVSADVPFIAAQKKCPVMDEPLDAMGGPYKVNAAGKAIYICCPGCAKKIAAEPQKWLAVLKSQGVDAPTIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQQ8</accession>
    <name>A0A518IQQ8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Phosphoserine phosphatase RsbU</fullName>
            <ecNumber evidence="4">3.1.3.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rsbU_1</name>
        <name evidence="4" type="ORF">Mal33_13710</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.3.3" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036424">
        <property type="term" value="F:L-phosphoserine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07228">
        <property type="entry name" value="SpoIIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00331">
        <property type="entry name" value="PP2C_SIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="SSF81606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="17"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="166"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="2">
        <location>
            <begin position="190"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="PPM-type phosphatase" evidence="3">
        <location>
            <begin position="267"/>
            <end position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV55400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="482" mass="52799" checksum="FD91345475FCFF5B" modified="2019-10-16" version="1">MDTFKHRWHQLPISRQLLVLVNAILFGFVVLFLVVDYRVRMDRHLNQKQIALTEEAKTMYESLLVAEPHGVEAIQNLVDNVCARMNTDDSPGHHIAADWRGLPYQAVSHGHASDEMLLAMRSAADSTVARSNATGALVVGSFTGPAGTVYISEKRSAVVGATRRSLLIQMFGVLLLGGITAFVVSAVLRQLIAKPIQGFVSALGSVAAGDLSVIARTRSCRELSYLADQINSMTEALDHAQRDHRVHMEKARQIQQNLRPTVNGLVGIDVAELFEPADDVGGDYYDVIPLSDGQYLLCVADVSGHGVPAAMAATLLKAFVSEAAKKSSSPAQILTDVNERYCEYVMMGHFATMTLLVVDPKRRQLTYANAGHELPFLQIGSETPVRLNVGDLILGVEDDTHYSEETIQLGDASRLVIVSDGVTEAFDPSEEQYGTDRIEQLMNTVKRCNARELVDAFESSIETFRKGRKAFDDTTLLVAQLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQZ5</accession>
    <name>A0A518IQZ5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_14880</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="105"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="174"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="176"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="205"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="248" mass="27085" checksum="54F7B760AA3DD14A" modified="2019-10-16" version="1">MKWQVRVCREQALLLILGNSVRSILASLCVLLLGIVAALPFRKSPHQEVEPPALERSQVASLVSPLEEIDVEAADLSGLSLSEMPYAIDEIPKPADSQDGLAAFPTLPKSRRPFSEGLVQPTPMLPDSNPSRGPDPMDIANRSQDWNIDLPLKYVQPQTGLKVEAIARKPLATPAEATSGSLSWNPSPNENRPAATGMRIHQAGSRQLGESSQSIEPEASVEPTQQYQNSPPPQQRPRKRYFVYEPAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IR14</accession>
    <name>A0A518IR14_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_15130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="147"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="174" mass="19169" checksum="ED7A9135DFF63A2D" modified="2019-10-16" version="1">MALRRSLHRLLLCPLLFAPLLGCKSESNSPPPQAPVSESTVLTDPAEPTEDSRVELHDLKAWFDEPNICYFEVQYDFVSGKPSHSYRVEVAFPGSENAGTKEMASWELKQSGKIRDGFAIHSMPIREMTVKMTEAFSPQDGYHAISDELTTAIDKLPADTEPTADAEPASGESD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRJ3</accession>
    <name>A0A518IRJ3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Streptothricin hydrolase</fullName>
            <ecNumber evidence="2">3.5.2.19</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">sttH</name>
        <name evidence="2" type="ORF">Mal33_16830</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.5.2.19" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000868">
        <property type="entry name" value="Isochorismatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00857">
        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="SSF52499"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isochorismatase" evidence="1">
        <location>
            <begin position="5"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="191" mass="20229" checksum="AFA38CFC0917EAFC" modified="2019-10-16" version="1">MTQRTALIVVDLQNDYFPGGKWELDGVEAAAVNAARIVAAVRETGGLVVHVRHEFPTQDAPFFAPGSEGAETHASVLPAAEEPVVVKQQINSFRDTELKAILDKAGVESVLVVGAMSHMCIDAVVRAAGDFGYACTVAHDACATLELEFQGTKIPANYVHGAFMAALAFGYAQVVSTEEAVQQLQAAEAEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRS0</accession>
    <name>A0A518IRS0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cadherin domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_17680</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007156">
        <property type="term" value="P:homophilic cell adhesion via plasma membrane adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006644">
        <property type="entry name" value="Cadg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002126">
        <property type="entry name" value="Cadherin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015919">
        <property type="entry name" value="Cadherin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002105">
        <property type="entry name" value="Dockerin_1_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036439">
        <property type="entry name" value="Dockerin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00028">
        <property type="entry name" value="Cadherin"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00404">
        <property type="entry name" value="Dockerin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00205">
        <property type="entry name" value="CADHERIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00112">
        <property type="entry name" value="CA"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00736">
        <property type="entry name" value="CADG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49313">
        <property type="entry name" value="SSF49313"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63446">
        <property type="entry name" value="SSF63446"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50268">
        <property type="entry name" value="CADHERIN_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cadherin" evidence="1">
        <location>
            <begin position="531"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="1">
        <location>
            <begin position="633"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="1">
        <location>
            <begin position="753"/>
            <end position="862"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="1">
        <location>
            <begin position="861"/>
            <end position="961"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="1">
        <location>
            <begin position="960"/>
            <end position="1062"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1314" mass="139871" checksum="DE8B331BF60972A0" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRT1</accession>
    <name>A0A518IRT1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cytochrome c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Mal33_17860</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00034">
        <property type="entry name" value="Cytochrom_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13442">
        <property type="entry name" value="Cytochrome_CBB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome c" evidence="5">
        <location>
            <begin position="93"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="5">
        <location>
            <begin position="304"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV55807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="433" mass="48028" checksum="C69B3F04E1689145" modified="2019-10-16" version="1">MKTTTYALLLIGLAALTGCEKPYVAEFEPNMVLAELVSMSVEEPMDQALAETQTALTRLFGTPDDPKLPDFLLEDPDLGTLVSMDNLVAASGSPSEEGRGLYRQHCSTCHGITGNGRGTTAALLDPYPRDYRMGKYKFKSTRRGSKPLREDLHFAITHGLDGTAMVAIPELNKNPEDVEALIDYVMYLTWRGEVERALLEEAELIDFAAGETLFDNAMVDKYLQKYKDDFDPETLTDEAQIEEYEMFAEQWEFIQDLTFGAVEGWLDAEDAVVEVPEPEDVPVPATIDEVVAAAKAPGDSPLKQSIQRGKELFVTERAACAKCHGPKGWGDGTNKDYDDWTKDWTLQRGIDPTDEAAQIPLIARGVLPPRLIKARDFRQGLYRGGSDPELLYLRIAAGIDGTPMPAASLEPNQIWDLVNYIRSLREDAPMSIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRW7</accession>
    <name>A0A518IRW7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hydroxypyruvate reductase</fullName>
            <ecNumber evidence="3">1.1.1.81</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ttuD</name>
        <name evidence="3" type="ORF">Mal33_17720</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.1.81" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008887">
        <property type="term" value="F:glycerate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016618">
        <property type="term" value="F:hydroxypyruvate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1480.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037035">
        <property type="entry name" value="GK-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038614">
        <property type="entry name" value="GK_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007835">
        <property type="entry name" value="MOFRL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025286">
        <property type="entry name" value="MOFRL_assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039760">
        <property type="entry name" value="MOFRL_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12227">
        <property type="entry name" value="PTHR12227"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13660">
        <property type="entry name" value="DUF4147"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05161">
        <property type="entry name" value="MOFRL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4147" evidence="2">
        <location>
            <begin position="15"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="domain" description="MOFRL" evidence="1">
        <location>
            <begin position="334"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="457" mass="47986" checksum="15D230B583324E60" modified="2019-10-16" version="1">MTTVSDSWKTSAGQAYQIWQAGVDAVLADRLVAETVTVDGQQLMFEDEPFDLAAIGRIAVVGGGKAAAAMAAGLETALGEQLCQSKQLHGWINIPDGTQRPLQWLHAHVARPAGVNEPTQAAADGTAEILQIVADLKPNDLCIALISGGGSALLTAPREGITLDEKIAVTRWLSGAGANIEQLNTVRKQLSDVKGGRLLSACKAANLVTLVISDVLGDPLDTIASGPTVADSSTAADALAVLQQFDPQQQLPASIYRVLAQPRLVPDASTGCVNHLQVIGNNAAAVDGAGIRAEQLGYSHAMQSARQSEGQAEQVGEHLAKMALSMLRQPGPDCLISGGEPVVQLAPQAERGRGGRNQQLVLAALGWLIQHGELTSEERARVTILSGGTDGEDGPTDAAGAFFNAEVWSRAEAQQLDWQDYLRRNDAYSFFEACGGLILTGPTNTNVCDVRVVTIAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IS09</accession>
    <name>A0A518IS09_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 9">Cytidine deaminase</fullName>
            <ecNumber evidence="6 9">3.5.4.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 9">Cytidine aminohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">cdd</name>
        <name evidence="11" type="ORF">Mal33_18490</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 9">This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 9">
            <text>2'-deoxycytidine + H(+) + H2O = 2'-deoxyuridine + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:13433"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15698"/>
            <dbReference type="ChEBI" id="CHEBI:16450"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.4.5"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>cytidine + H(+) + H2O = NH4(+) + uridine</text>
            <dbReference type="Rhea" id="RHEA:16069"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16704"/>
            <dbReference type="ChEBI" id="CHEBI:17562"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.4.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3 9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5 9">Belongs to the cytidine and deoxycytidylate deaminase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.5" evidence="6 9"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004126">
        <property type="term" value="F:cytidine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047844">
        <property type="term" value="F:deoxycytidine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006262">
        <property type="entry name" value="Cyt_deam_tetra"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="SSF53927"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01354">
        <property type="entry name" value="cyt_deam_tetra"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="10">
        <location>
            <begin position="14"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00003949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00006576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00018266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU364006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QDV55870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="143" mass="15211" checksum="1E4BBF1B5A6D70FC" modified="2019-10-16" version="1">MNPDDAKPAAEDPDPLTELIDVACDVRQQAYAPYSNFQVGAALLAESGAIYRGCNVENVSFGLTLCAERTAASAAVAAGERAFKTLVLVTTGSVSPCGACRQFLIEFGPALEIVLVEASTRQITQRISLAELLPNQFNDFREG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IS70</accession>
    <name>A0A518IS70_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_19000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022096429" evidence="2">
        <location>
            <begin position="26"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="309"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="324"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="345"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="371" mass="41660" checksum="B79872F21F0D1896" modified="2019-10-16" version="1" precursor="true">MLRDLLKTTLFGTAIAIATTSAAFAQNEDRDRGADAPPRRPAGEHRRPGGDVEAPMHGIEGERRGLRGDAERPQRREGERRGPGGDRGRGAMDSRQHDDMNRGDSNRPDRFEGERRRPGGDAERPQRREGERRGPGGDRGRGAMDSRHHDDMKRGDSNRPDRFEGERRRPGGDEPRSHRDAGERRGPSGDWGRGPSDSRHHHGMNRGDSYRSYRFAGERRGARGDWGRGPSDSRHHHGMNRGESYRSHRFAGERRGARGDWGRGPSESRRHHGMNRGESYRSHRFAAEHRGPRGDRGRDAMEPRHHRGEKSFKKGKGKSKRGEKSAKHRDGKNKKLSAKSKNGKRDGSKKGKGKGKKKHRGGDRGKGRGAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISF4</accession>
    <name>A0A518ISF4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Serine protease HhoB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">hhoB_2</name>
        <name evidence="3" type="ORF">Mal33_20060</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S1C family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001940">
        <property type="entry name" value="Peptidase_S1C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13180">
        <property type="entry name" value="PDZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00834">
        <property type="entry name" value="PROTEASES2C"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDZ" evidence="2">
        <location>
            <begin position="468"/>
            <end position="551"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="647" mass="70221" checksum="76EE4AB4B653477B" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISL5</accession>
    <name>A0A518ISL5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Diaminopimelate decarboxylase</fullName>
            <ecNumber evidence="2">4.1.1.20</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">lysA_2</name>
        <name evidence="2" type="ORF">Mal33_20660</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="4.1.1.20" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008836">
        <property type="term" value="F:diaminopimelate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901564">
        <property type="term" value="P:organonitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd06842">
        <property type="entry name" value="PLPDE_III_Y4yA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.37.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009006">
        <property type="entry name" value="Ala_racemase/Decarboxylase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022657">
        <property type="entry name" value="De-COase2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022644">
        <property type="entry name" value="De-COase2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022653">
        <property type="entry name" value="De-COase2_pyr-phos_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000183">
        <property type="entry name" value="Orn/DAP/Arg_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042152">
        <property type="entry name" value="Y4yA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02784">
        <property type="entry name" value="Orn_Arg_deC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01179">
        <property type="entry name" value="ODADCRBXLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50621">
        <property type="entry name" value="SSF50621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="SSF51419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00878">
        <property type="entry name" value="ODR_DC_2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00879">
        <property type="entry name" value="ODR_DC_2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Orn_Arg_deC_N" evidence="1">
        <location>
            <begin position="72"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="498" mass="55075" checksum="C79548CB3F00B98A" modified="2019-10-16" version="1">MTCSIETSDPTDRQRIATLRSFCQGTPPLDAVLEPWIVELLSDRRPELDAACERFGSPLNVISAEPMVRNIEQLNRVADERDLRFQVYFARKANKCLAFVDAANRIGAGIDVASEAECQQAIERGVRSADILCTAAIKPRSLIRLCVQNRVPIAIDNIDELRCVEVVAAELAIEAEVAIRISGFEHDGEKLFSRFGFDIDEAGHLLRQIPDPSGEASVRVCGIHFHLDGYSAAQRISAIRQSLPLIDRFRSLGHDVRFLDIGGGLPMCYLESGSQWEAFHAEHRSALLGERKPITFKNDGLGFINVDGKLHGRRNTYPYYQSPTAAAWLAGVLDAEFEPGETLAAAIRQRQLQLRCEPGRSVLNGCGITVARVEFVKRHPSGDSFVGVAMNRTQCRTGSDDFLVDPLVLQTNESASLDRNEALAGYLVGAYCTESELISLRRFRFPQGIAAGDLVVLPNTAGYFMHFLESRSHQFPLATNVVVDRNGEELFRVDAIDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISS7</accession>
    <name>A0A518ISS7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative methyltransferase YcgJ</fullName>
            <ecNumber evidence="2">2.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ycgJ_2</name>
        <name evidence="2" type="ORF">Mal33_21260</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.1.1.-" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="1">
        <location>
            <begin position="47"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="229" mass="25064" checksum="232A4A3B82E53020" modified="2019-10-16" version="1">MLPRTLEPESMDDPAEAASYDDMNHSAVNIRFVDDLLAGGSIGNDILDLGTGTAQIPILLCERMPEIRIMALDAAASMLELAIYNIEIASAIERIQLMQGDAKAMDDFEDEMFDCVMCNSLIHHLPEPQPTFAEIHRLTAIDGRIFVRDLCRPDSADAVEALVVQYAGKESDVAQQLFRQSLHAALTLDEVKQMVAAAGMSPDAVQMTSDRHWTLDVRKSAACQEGTAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IT19</accession>
    <name>A0A518IT19_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Holliday junction ATP-dependent DNA helicase RuvB</fullName>
            <ecNumber evidence="7">3.6.4.12</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ruvB_2</name>
        <name evidence="7" type="ORF">Mal33_22240</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.6.4.12" evidence="7"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009378">
        <property type="term" value="F:four-way junction helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041445">
        <property type="entry name" value="AAA_lid_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004605">
        <property type="entry name" value="DNA_helicase_Holl-junc_RuvB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008824">
        <property type="entry name" value="RuvB-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008823">
        <property type="entry name" value="RuvB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42848">
        <property type="entry name" value="PTHR42848"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17864">
        <property type="entry name" value="AAA_lid_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05491">
        <property type="entry name" value="RuvB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05496">
        <property type="entry name" value="RuvB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="5" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="3 7" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="6">
        <location>
            <begin position="44"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV56242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="315" mass="35386" checksum="0CBFF01F5E3C91C6" modified="2019-10-16" version="1">MKETEPIITSLSQVVGQARAVRVLQTALDAYWHERRKQGEENVSFPHLLMAGPGGTGKTMLSELVARELCTEVHVELAQNISNIGQMQGLLMMLDKPGQILFLDEIHQLNESVQVCLYRALEERKLFLGGNKKPVTLPPFTLIGATTHEYMLTTSSRDRFQILIRLSHYDTDEMTVLIDQRAKRLGWGIDPKSVHELAKRSRGVPRLAVRMLEAAKRSCSANGCDFIESIHVAEMLEMEGIDPLGFDPVEQTYLQLLKQHQGAVRLNVLATHLGLPRQSIEMFESDFMRLGLITKNEKGRCLTPAGHEHLKVSNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITA1</accession>
    <name>A0A518ITA1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Planctomycete cytochrome C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_23010</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011429">
        <property type="entry name" value="Cyt_c_Planctomycete-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011444">
        <property type="entry name" value="DUF1549"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022655">
        <property type="entry name" value="DUF1553"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07635">
        <property type="entry name" value="PSCyt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07583">
        <property type="entry name" value="PSCyt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07587">
        <property type="entry name" value="PSD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021794382" evidence="1">
        <location>
            <begin position="32"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="domain" description="PSCyt1" evidence="4">
        <location>
            <begin position="50"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="PSCyt2" evidence="2">
        <location>
            <begin position="158"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="domain" description="PSD1" evidence="3">
        <location>
            <begin position="387"/>
            <end position="521"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV56319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="819" mass="90798" checksum="026A574E267B1FF9" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITE5</accession>
    <name>A0A518ITE5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_23490</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="52" mass="5824" checksum="CEC61AF28D39E216" modified="2019-10-16" version="1">MGSNDADWPRDSQPRTSLRGFDPPFQTAFGGAVKRGLHDIRQRLPLTRSTRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITG5</accession>
    <name>A0A518ITG5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">1,4-alpha-glucan branching enzyme GlgB</fullName>
            <ecNumber evidence="9">2.4.1.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Alpha-(1-&gt;4)-glucan branching enzyme</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Glycogen branching enzyme</fullName>
            <shortName evidence="9">BE</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9 12" type="primary">glgB</name>
        <name evidence="12" type="ORF">Mal33_23660</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>Transfers a segment of a (1-&gt;4)-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain.</text>
            <dbReference type="EC" id="2.4.1.18"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Glycan biosynthesis; glycogen biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.18" evidence="9"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00164"/>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003844">
        <property type="term" value="F:1,4-alpha-glucan branching enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102752">
        <property type="term" value="F:1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043169">
        <property type="term" value="F:cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005978">
        <property type="term" value="P:glycogen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02855">
        <property type="entry name" value="E_set_GBE_prok_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00685">
        <property type="entry name" value="GlgB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006048">
        <property type="entry name" value="A-amylase/branching_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037439">
        <property type="entry name" value="Branching_enzy"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006407">
        <property type="entry name" value="GlgB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044143">
        <property type="entry name" value="GlgB_N_E_set_prok"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="Glyco_hydro_13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004193">
        <property type="entry name" value="Glyco_hydro_13_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43651">
        <property type="entry name" value="PTHR43651"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02806">
        <property type="entry name" value="Alpha-amylase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02922">
        <property type="entry name" value="CBM_48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000463">
        <property type="entry name" value="GlgB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="SSF81296"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01515">
        <property type="entry name" value="branching_enzym"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7 9" id="KW-0320">Glycogen biosynthesis</keyword>
    <keyword evidence="4 9" id="KW-0321">Glycogen metabolism</keyword>
    <keyword evidence="5 9 12" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aamy" evidence="11">
        <location>
            <begin position="257"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="9 10">
        <location>
            <position position="416"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="9 10">
        <location>
            <position position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000463-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QDV56377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="737" mass="83830" checksum="20EECB08E3599C5F" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITV2</accession>
    <name>A0A518ITV2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_25060</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="139" mass="14986" checksum="B1B7415492A72BC4" modified="2019-10-16" version="1">MATGNGSTVTFATSGFTARFEEIGEVKQTRGKIKDSDLASEDFHEYLPEDLAEPGEREFKIFWEGDNAPPSINSAAELVTVTHKLEAGQATAAKFIGSAFITDLTVDPKHANNETKQGTLKIQYDNKSTAPAFTEAVAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITX4</accession>
    <name>A0A518ITX4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">D-ribose-binding periplasmic protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rbsB_1</name>
        <name evidence="3" type="ORF">Mal33_25340</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025997">
        <property type="entry name" value="SBP_2_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13407">
        <property type="entry name" value="Peripla_BP_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021730945" evidence="1">
        <location>
            <begin position="23"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="domain" description="Peripla_BP_4" evidence="2">
        <location>
            <begin position="45"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="328" mass="34282" checksum="3E6B698AAFCAF196" modified="2019-10-16" version="1" precursor="true">MKTNKRRSLPLILSAIAMMVLAGGCSSKTATNESADPAAAGKPRIALVMKSLANEFFSTMEKGAEKHQAANSDQYELLVNGIKDESDLGRQVALVDEMVAAGVDAIVIAPADSKALVPALRKAQQAGVVVVNIDNRLDAEVLKSENVTIPFVGPDNQAGAKQVGDLLAASLAKGDQVAVLEGKTTAFNGIQRRLGFEAAMKQAGMEIVSSQSADWETNKANTITASMLSEHPQIKAILAANDSMALGAVAAIKSAGKTGEVLVVGFDNIGAVQQLIREEKVLATADQHGDQLAVYGIETALKILKDPAAATEDVQTPVDLVTKETLAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUE0</accession>
    <name>A0A518IUE0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_27090</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
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            <end position="19"/>
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    <feature type="region of interest" description="Disordered" evidence="1">
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            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="903" mass="101334" checksum="CE980C124BC97305" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
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                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
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                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
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            <strain evidence="2 3">Mal33</strain>
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    <feature type="transmembrane region" description="Helical" evidence="1">
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    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
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</entry>
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                <person name="Peeters S.H."/>
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                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
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                <person name="Jeske O."/>
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                <person name="Lage O.M."/>
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                <person name="Merkel B.J."/>
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                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">Mal33</strain>
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    </reference>
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            <begin position="65"/>
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    <evidence type="ECO:0000256" key="1">
        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="85" mass="9616" checksum="06DF731DDAF9953D" modified="2019-10-16" version="1">MIKLSRELTEQALLHPNGVQCQGDGVDKTFVIIDAEVMLQMREAISRNDHAEIQAGINDMEAGRMQSAEEAHRHGREDLISRFKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUT8</accession>
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    <protein>
        <submittedName>
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    <organism evidence="1 2">
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    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <dbReference type="EMBL" id="QDV56853.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="293" mass="31339" checksum="C4EDBF75E34F6814" modified="2019-10-16" version="1">MAVKITWKTTPEISPLCAAAAVASGLPVADAQLPGLIGHCVQSISDRLAVADLDVDRFWNCLIAAGDRPRDHRARVEAALLQAGCGELAADSIAPTISGQLADLKIAYAEAFPKLGEQLPLRARVLQEQWEARGPGLIAVIGKLTHRDLMPKKGTVAFVQPALGGGGDASPETGLVWIEAVLANPFPDIPEVVRLGWLLARLGLGRKSASKLVDAKHLPDLAALALLPIVLEAARDVELLGDVELSRLMDAWNTRRINSNCTAESLNQWWSQMREGTTPFPVGLKALDRILTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
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    <name>A0A518IUU4_9BACT</name>
    <protein>
        <submittedName>
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                <person name="Vollmers J."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
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    <evidence type="ECO:0000313" key="1">
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
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    </evidence>
    <sequence length="132" mass="14997" checksum="CE77955F59DD067C" modified="2019-10-16" version="1">MTDAATPKSELLEMQRAFVKRCAKGEFVEVMEDYYADDAYQIEGDGSRREGKANMIAFEKQFLTQVKQFHGVDIRSIAVASDDGKGNGVTMAEYTIKADMIDGSKFWPEQVQVSTWKNGKIIALRFYYDPNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IV01</accession>
    <name>A0A518IV01_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Multidrug resistance protein MdtC</fullName>
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        <name evidence="3" type="primary">mdtC_4</name>
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    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
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                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
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                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
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                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
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    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="15"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="378"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="404"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="431"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="503"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="537"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="580"/>
            <end position="603"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="955"/>
            <end position="977"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="984"/>
            <end position="1004"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1010"/>
            <end position="1035"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1056"/>
            <end position="1075"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1087"/>
            <end position="1113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="330"/>
            <end position="354"/>
        </location>
    </feature>
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        <location>
            <begin position="330"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1141" mass="125206" checksum="4D1CA37DDCFC81AC" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IV21</accession>
    <name>A0A518IV21_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TatD related DNase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_29370</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallo-dependent hydrolases superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001130">
        <property type="entry name" value="TatD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012022">
        <property type="entry name" value="UCP005295"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42658">
        <property type="entry name" value="PTHR42658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01026">
        <property type="entry name" value="TatD_DNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005295">
        <property type="entry name" value="UCP005295_TatD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR005295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="276" mass="31248" checksum="5511FDA852AE4964" modified="2019-10-16" version="1">MDYIDPHIHMVSRITDDYATLARMGCVAVSEPAFWAGFDRGSVDGFRDYFCQLTEVEPRRAAQYGIQHFTWLCINAKEAENVELSREVIAMIPEFLDRPGVLGIGEIGLNKNTPNEATIFIEHMELAIAHEQSILIHTPHLEDKYQGTRMILDMLCGDSRVNRDRVLVDHVEEHTVAEVLDRGFWAGMTLYPISKCTPDRAVDMIEMYGAERLLVNSAGDWGPSKPTAVPDLIFECRQRGIPEATIRKVVYENPVAFFSQSKNFNFQPRDGQQAPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IV24</accession>
    <name>A0A518IV24_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_29380</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="119" mass="13546" checksum="A8DEFAC9AFF44A55" modified="2019-10-16" version="1">MRRRTRGNDSTVKADDLPPPAKRAFRILTTDWAATMNSQQTASQVLDRHYLEARARILEIAAIFDRIDRAQGSTGEDPRDALLRQGIEILSDSAANRAEQVQKLFSREYNADWRDEMGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVA2</accession>
    <name>A0A518IVA2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_30060</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="173" mass="18247" checksum="E96DB8F3676F86E0" modified="2019-10-16" version="1">MKKLTTTFAIGFACLAISLTGCKPAPTADSEAADAHQGEAAHAHPTEGPHHGSLIELGNEEYHAELVHDDAAGTVTIYVLDSAATAQVPIAATEITINATHDGTPEQFLLAASPDENDPEGQSSRFVSTDKELAAHLDEEGAEPRLVLSINGKSYRGTIHHDHDGEGHHDHGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVG2</accession>
    <name>A0A518IVG2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Procyclic acidic repetitive protein (PARP)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_30760</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012495">
        <property type="entry name" value="TadE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07811">
        <property type="entry name" value="TadE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="26"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="155"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="176"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="268" mass="29065" checksum="46A597998004862B" modified="2019-10-16" version="1">MKNRNQEFSRQSGSTDGQLPFTSRTGAYVVECAVILPILLMLILGSIEFVRISNIRHALDSASYEACRRVIVPGASTAEATERANEILNRYGLSVAKIQVTPNQILESTPEVTVAITAAASENAWYLTKYTGGSALSAETSLLTERAATVLASAIATPPPPPKPTPTPTPTPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPDPTPPPPPKPKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVH6</accession>
    <name>A0A518IVH6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Signal transduction histidine-protein kinase BarA</fullName>
            <ecNumber evidence="10">2.7.13.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">barA_10</name>
        <name evidence="10" type="ORF">Mal33_30880</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="10"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="47"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="72"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="9">
        <location>
            <begin position="221"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="8">
        <location>
            <begin position="273"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="9">
        <location>
            <begin position="347"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="8">
        <location>
            <begin position="400"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="9">
        <location>
            <begin position="461"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="6">
        <location>
            <begin position="529"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="7">
        <location>
            <begin position="770"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="7">
        <location>
            <begin position="919"/>
            <end position="1039"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1047"/>
            <end position="1097"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="3">
        <location>
            <position position="824"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="3">
        <location>
            <position position="968"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV57087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1097" mass="121752" checksum="ABD9F3F261471844" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVP7</accession>
    <name>A0A518IVP7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Inositol-1-monophosphatase</fullName>
            <ecNumber evidence="6">3.1.3.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">suhB_2</name>
        <name evidence="7" type="ORF">Mal33_31600</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>a myo-inositol phosphate + H2O = myo-inositol + phosphate</text>
            <dbReference type="Rhea" id="RHEA:24056"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17268"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:84139"/>
            <dbReference type="EC" id="3.1.3.25"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the inositol monophosphatase superfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.25" evidence="6"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008934">
        <property type="term" value="F:inositol monophosphate 1-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052832">
        <property type="term" value="F:inositol monophosphate 3-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052833">
        <property type="term" value="F:inositol monophosphate 4-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046855">
        <property type="term" value="P:inositol phosphate dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01639">
        <property type="entry name" value="IMPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033942">
        <property type="entry name" value="IMPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020583">
        <property type="entry name" value="Inositol_monoP_metal-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000760">
        <property type="entry name" value="Inositol_monophosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020550">
        <property type="entry name" value="Inositol_monophosphatase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022337">
        <property type="entry name" value="Inositol_monophosphatase_SuhB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00459">
        <property type="entry name" value="Inositol_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00377">
        <property type="entry name" value="IMPHPHTASES"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01959">
        <property type="entry name" value="SBIMPHPHTASE"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00629">
        <property type="entry name" value="IMP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00630">
        <property type="entry name" value="IMP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV57159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="274" mass="29584" checksum="FB75C35BE5B97E97" modified="2019-10-16" version="1">MSDLDREQIMEVARQAAVAAGGVLRRYYETGVQIRSKADATGGQHNLVSDADLESEQTIAGVIRAAYPDHELLGEEELSGAIEAEHLWVIDPLDGTNNFAHSIPHFAISIAYCYRGQPQVGIVYNPIREDWFTAIAGAGAWSNDRRLSVSSEESLGQAMLACGFHYDRGKLMQATLDAIGELFSQHQIHGIRRMGAAALDLCGVAAGQFGGFFEYFLSPWDFAAGKLIVEEAGGTITTSRGEPLGLQAGGVIVTNGKLHPKLSEIVQRHQPSGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVX5</accession>
    <name>A0A518IVX5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">1,3-propanediol dehydrogenase</fullName>
            <ecNumber evidence="3">1.1.1.202</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">dhaT</name>
        <name evidence="3" type="ORF">Mal33_32460</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.1.202" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047516">
        <property type="term" value="F:1,3-propanediol dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001670">
        <property type="entry name" value="ADH_Fe/GldA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018211">
        <property type="entry name" value="ADH_Fe_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039697">
        <property type="entry name" value="Alcohol_dehydrogenase_Fe"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11496">
        <property type="entry name" value="PTHR11496"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00465">
        <property type="entry name" value="Fe-ADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00913">
        <property type="entry name" value="ADH_IRON_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe-ADH" evidence="2">
        <location>
            <begin position="11"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="380" mass="40091" checksum="50E9D2A2150F21AD" modified="2019-10-16" version="1">MQPFDFQLRPRIVFGAGVIEQLGPLAVELGARTVLVVSDPGVVKAGHFGTGLLSLEAAGLVVHSFHDFTENPTTDFIDAGVEVARRVKPDLIVGLGGGSSMDCAKGINFVYSCGGEIKDYWGVGKATADMLPMIAVPTTSGTGSEAQSFALISDAETHVKMACGDPRAACAVALLDPALTLTQPYAVTALTGIDALSHALETHVTTRRNAVSSTFSRQAFRMIAGNLARVLEVGDDLEARGEMQFGACLAGIAIETSMLGAAHATANPLTARFGITHGQAVGLMLPHVVLFNGRDYPELYAELLAEIDPGESQHDAPLQIAQRVTELVGKAGLKTKLSELEIPRDALPQLAEDATQQWTGTFNPIPVNAENLLALYQAAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IW14</accession>
    <name>A0A518IW14_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">30S ribosomal protein S17</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3 5" type="primary">rpsQ</name>
        <name evidence="5" type="ORF">Mal33_32820</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Part of the 30S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the universal ribosomal protein uS17 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01345_B">
        <property type="entry name" value="Ribosomal_S17_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019984">
        <property type="entry name" value="Ribosomal_S17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000266">
        <property type="entry name" value="Ribosomal_S17/S11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10744">
        <property type="entry name" value="PTHR10744"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00366">
        <property type="entry name" value="Ribosomal_S17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00973">
        <property type="entry name" value="RIBOSOMALS17"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03635">
        <property type="entry name" value="uS17_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 3" id="KW-0699">rRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="97"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV57278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="117" mass="13132" checksum="21C49BB8253627BC" modified="2019-10-16" version="1">MPKRVLTGVVTGDKMAKTRRVEIKRLVKHPKYKKYVRRRTVCYAHDEQNESAVGDLVEIKESRPMSKLKRWELIRVVEKSTAVDVAALRAARKHAASEAENEAIEAAHGGDAEAPKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWL5</accession>
    <name>A0A518IWL5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Choline-sulfatase</fullName>
            <ecNumber evidence="5">3.1.6.6</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">betC_6</name>
        <name evidence="5" type="ORF">Mal33_34900</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="PTM">
        <text evidence="1">The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.</text>
    </comment>
    <dbReference type="EC" id="3.1.6.6" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047753">
        <property type="term" value="F:choline-sulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021713707" evidence="3">
        <location>
            <begin position="36"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase" evidence="4">
        <location>
            <begin position="39"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="107"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="167"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="modified residue" description="3-oxoalanine (Cys)" evidence="1">
        <location>
            <position position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR600917-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV57480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="520" mass="57729" checksum="7E332568DF5843DE" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWP9</accession>
    <name>A0A518IWP9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_35170</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="65" mass="7266" checksum="AE3C475F100CE8EF" modified="2019-10-16" version="1">MLLIGSRNLHPHQLRWRPPVAPDRWTADSPTGRCRIGRGAFSAAEASKHESEELTHSHILCIVAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWR7</accession>
    <name>A0A518IWR7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transcriptional regulatory protein ZraR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">zraR_6</name>
        <name evidence="8" type="ORF">Mal33_35330</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002197">
        <property type="entry name" value="HTH_Fis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002078">
        <property type="entry name" value="Sigma_54_int"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025662">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025944">
        <property type="entry name" value="Sigma_54_int_dom_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00158">
        <property type="entry name" value="Sigma54_activat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01590">
        <property type="entry name" value="HTHFIS"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00675">
        <property type="entry name" value="SIGMA54_INTERACT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00688">
        <property type="entry name" value="SIGMA54_INTERACT_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50045">
        <property type="entry name" value="SIGMA54_INTERACT_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Response regulatory" evidence="7">
        <location>
            <begin position="8"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma-54 factor interaction" evidence="6">
        <location>
            <begin position="149"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="5">
        <location>
            <position position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV57523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="471" mass="51398" checksum="D4FBE125D5BDE097" modified="2019-10-16" version="1">MNLSPSARILIADDEPLYLRTTGELLRKAGYTCVCVSDAGAALQALHEAPFDLILSDLNMPGNLKLELLHEGRGNWPQIPMIVITGVPSVPSAIESVRLGIADYLLKPVKFEDLLGSVRRALAQSSTTSHAAAAVPDGQRPLSETYPEIIGRCPQMVELLDIVDRVAAVDTNILITGESGTGKEVIARAIHRHSPRRENRFQVIDCTAIPESLFESALFGHVKGSFTGAVRDQVGLLSQCDHGTAFFDELGELPSTSQAKLLRAIQEQTFTPVGQSTPIQVDTRFICATNRNLEMEVAAGRFRRDLFYRLGVIHIELPPLRDRGDDVLLLAERFLPQLKPANSTVSRFSDSVLQCFQQYDWPGNIRELRNAIERATALARTDCVEIGDLPEALRQAASGGTRKSADASSVSALKNASRDEAIDSAEHAYLASLLEKHVGNISQAAQQAGLSRQGMHKLLKKHGIAAADYRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXH2</accession>
    <name>A0A518IXH2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DNA-directed RNA polymerase subunit beta'</fullName>
            <shortName evidence="7">RNAP subunit beta'</shortName>
            <ecNumber evidence="7">2.7.7.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">RNA polymerase subunit beta'</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Transcriptase subunit beta'</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 11" type="primary">rpoC</name>
        <name evidence="11" type="ORF">Mal33_37900</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 8">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7 8">
            <text>a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="7">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 2 Zn(2+) ions per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7 8">Belongs to the RNA polymerase beta' chain family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="7"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.274.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.860.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01322">
        <property type="entry name" value="RNApol_bact_RpoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045867">
        <property type="entry name" value="DNA-dir_RpoC_beta_prime"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012754">
        <property type="entry name" value="DNA-dir_RpoC_beta_prime_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000722">
        <property type="entry name" value="RNA_pol_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006592">
        <property type="entry name" value="RNA_pol_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007080">
        <property type="entry name" value="RNA_pol_Rpb1_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007066">
        <property type="entry name" value="RNA_pol_Rpb1_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042102">
        <property type="entry name" value="RNA_pol_Rpb1_3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007083">
        <property type="entry name" value="RNA_pol_Rpb1_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007081">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044893">
        <property type="entry name" value="RNA_pol_Rpb1_clamp_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038120">
        <property type="entry name" value="Rpb1_funnel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19376">
        <property type="entry name" value="PTHR19376"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04997">
        <property type="entry name" value="RNA_pol_Rpb1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00623">
        <property type="entry name" value="RNA_pol_Rpb1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04983">
        <property type="entry name" value="RNA_pol_Rpb1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05000">
        <property type="entry name" value="RNA_pol_Rpb1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04998">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00663">
        <property type="entry name" value="RPOLA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02386">
        <property type="entry name" value="rpoC_TIGR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 7 8" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 7 8" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 7 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="RPOLA_N" evidence="10">
        <location>
            <begin position="234"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1398"/>
            <end position="1446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1424"/>
            <end position="1438"/>
        </location>
    </feature>
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        </source>
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        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1446" mass="160740" checksum="E930745EF43D9281" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
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    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
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                <person name="Pinto D."/>
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                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
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                <person name="Jeske O."/>
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</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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                <person name="Kohn T."/>
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                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
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                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
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                <person name="Spormann A.M."/>
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                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
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                <person name="Devos D.P."/>
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                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="project" value="UniProtKB-KW"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
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        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="32"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="3">
        <location>
            <begin position="66"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="3">
        <location>
            <begin position="438"/>
            <end position="603"/>
        </location>
    </feature>
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        <location>
            <begin position="925"/>
            <end position="981"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV57981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="981" mass="106280" checksum="592CE672F6466DC3" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IY20</accession>
    <name>A0A518IY20_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Sulfite reductase [NADPH] flavoprotein alpha-component</fullName>
            <ecNumber evidence="5">1.8.1.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">cysJ</name>
        <name evidence="5" type="ORF">Mal33_39960</name>
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    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.8.1.2" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004783">
        <property type="term" value="F:sulfite reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001094">
        <property type="entry name" value="Flavdoxin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00258">
        <property type="entry name" value="Flavodoxin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00369">
        <property type="entry name" value="FLAVODOXIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="SSF52343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0249">Electron transport</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="48"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="domain" description="Flavodoxin-like" evidence="3">
        <location>
            <begin position="97"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="4">
        <location>
            <begin position="248"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV57980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="557" mass="61666" checksum="D405EEF2410B3050" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IY70</accession>
    <name>A0A518IY70_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CHAD domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_40380</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.40.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007899">
        <property type="entry name" value="CHAD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038186">
        <property type="entry name" value="CHAD_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05235">
        <property type="entry name" value="CHAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00880">
        <property type="entry name" value="CHAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51708">
        <property type="entry name" value="CHAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CHAD" evidence="1">
        <location>
            <begin position="8"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="306" mass="35703" checksum="BF2C63B430E6858D" modified="2019-10-16" version="1">MKIRLRVDESVEEGIQRIAKTYIQRSIDDWSDPRLDRTEVVHDVRKRCKMIRGMLRMVRPAIGDAYDLENVWFRDASRKLSGLRDADATLEAFDLLRQHSAHSLPRKFMDRVNKVLAKRSEVASTGPLDWQPFFTEAIQEMQAALDRVPQWTCADEGFAAIGPGFAKTYRRGARAMQAARREPTDEHLHDWRKHAKYQWYQVLMLRDLSKSKLSIRAKQLKRLTDLLGDDHDLVVLHQLLTQHPDFEKLRGAKAFGKLMQSIDRRRAKLQKQARKLGKRLYATSSKKFTNRLEQAWEAWRSVEPVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IY83</accession>
    <name>A0A518IY83_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_40500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1021"/>
            <end position="1046"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1503" mass="161607" checksum="B2A4BD4B6D882646" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYD0</accession>
    <name>A0A518IYD0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">Cyclic pyranopterin monophosphate synthase</fullName>
            <ecNumber evidence="3 5">4.6.1.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Molybdenum cofactor biosynthesis protein C</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">moaC</name>
        <name evidence="7" type="ORF">Mal33_40910</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>(8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate = cyclic pyranopterin phosphate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:49580"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:59648"/>
            <dbReference type="ChEBI" id="CHEBI:131766"/>
            <dbReference type="EC" id="4.6.1.17"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 5">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homohexamer; trimer of dimers.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the MoaC family.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.17" evidence="3 5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00344"/>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061799">
        <property type="term" value="F:cyclic pyranopterin monophosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01420">
        <property type="entry name" value="MoaC_PE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01224_B">
        <property type="entry name" value="MoaC_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023045">
        <property type="entry name" value="Mo_CF_biosynth-C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036522">
        <property type="entry name" value="MoaC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002820">
        <property type="entry name" value="Mopterin_CF_biosynth-C_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01967">
        <property type="entry name" value="MoaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55040">
        <property type="entry name" value="SSF55040"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00581">
        <property type="entry name" value="moaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 5" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MoaC" evidence="6">
        <location>
            <begin position="16"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="76"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="113"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV58074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="164" mass="17716" checksum="BBC8D5AC26CEECBB" modified="2019-10-16" version="1">MPPSSSHFDDAGNARMVDITDKAITVRTAVAEVSVRMQPETLQQVRERSLKKGDVLAVARLAAISGSKLTSTLIPLCHAIPIEAVAVDFQFEDSATLVCRSTVKTTARTGVEMEAMTACSVAALTVYDMCKSIDRGIEIDGLKLLHKSGGKSGDFDRDMREESR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYG1</accession>
    <name>A0A518IYG1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">2-dehydro-3-deoxy-phosphogluconate aldolase</fullName>
            <ecNumber evidence="3">4.1.2.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">eda</name>
        <name evidence="5" type="ORF">Mal33_41360</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2-dehydro-3-deoxy-6-phospho-D-gluconate = D-glyceraldehyde 3-phosphate + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:17089"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:57569"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="4.1.2.14"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the KHG/KDPG aldolase family.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.14" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008675">
        <property type="term" value="F:2-dehydro-3-deoxy-phosphogluconate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00452">
        <property type="entry name" value="KDPG_aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000887">
        <property type="entry name" value="Aldlse_KDPG_KHG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031337">
        <property type="entry name" value="KDPG/KHG_AS_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031338">
        <property type="entry name" value="KDPG/KHG_AS_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30246">
        <property type="entry name" value="PTHR30246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01081">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01182">
        <property type="entry name" value="eda"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00159">
        <property type="entry name" value="ALDOLASE_KDPG_KHG_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00160">
        <property type="entry name" value="ALDOLASE_KDPG_KHG_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV58119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="223" mass="23362" checksum="30E0A6DA04FC9DD6" modified="2019-10-16" version="1">MKSQFPDEMLQRIQSCGVVAVIVIDNPQDAVPLAQALLAGGIQAIELTLRTPAAIEAIRAIAAEVPEVLVGAGTILTPEQVDEVVDAGAAFAVAPGLNRRVVERCQSRGLPFAPGIVTPSDIELAVELGCRELKFFPAEPSGGMSYLKSMAAPYAHLGLQFIPLGGLDAGNMASYLGSPLVPAIGGSWIAPRKLIQQQAWAEITQNATEASRIVAATQNKEIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYH7</accession>
    <name>A0A518IYH7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Plasmid stabilization system protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_41600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2310.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007712">
        <property type="entry name" value="RelE/ParE_toxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035093">
        <property type="entry name" value="RelE/ParE_toxin_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05016">
        <property type="entry name" value="ParE_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1277">Toxin-antitoxin system</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="66" mass="7945" checksum="752DF44DD09E8A53" modified="2019-10-16" version="1">MSGIYEKIQLLRAHPRLGQRYEPIVDREVRETLYGHYRIAYLIVNEQRVEILGIFHGAMEIERYLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYM7</accession>
    <name>A0A518IYM7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Mal33_42090</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022791">
        <property type="entry name" value="L-PG_synthase/AglD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03706">
        <property type="entry name" value="LPG_synthase_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="14"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="52"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="88"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="131"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="164"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="222"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="260"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="301"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV58192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="344" mass="36948" checksum="FB4625AEAE1592C0" modified="2019-10-16" version="1">MNTTPSKTTSLKTVLLTVAKFAVPVGIVWYLVSQIQPQQWLALQNSPKQYSLLAMALLIGLSATLLSYVRWWLLVRSHNIPLTPTEGIRLAAIGFLLNFVSIGAVGGDLFKAYFLARRTPGKKIEVFATALVDRVVGLYGLLVVASVALWMIGDSLAGDDVTMIRAVVYTLTLAGAAFMLGVVLGGSLIDQALDRILNVPMVGPFVHRIADPLRAFRHHTAAFMVTIGMSVVVHILLGVAIYFIAAGLYEHPPTLAEHMVIVPIANAVAGLPISLAGIGVFEGALDHLYAKLPTTPTDASGTIVGLVYEIVKIAIAMIGIVFYWTGQREVRESFQAVAASDDKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYP2</accession>
    <name>A0A518IYP2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glyoxylate/hydroxypyruvate reductase B</fullName>
            <ecNumber evidence="6">1.1.1.79</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ghrB_2</name>
        <name evidence="6" type="ORF">Mal33_42140</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.79" evidence="6"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030267">
        <property type="term" value="F:glyoxylate reductase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006139">
        <property type="entry name" value="D-isomer_2_OHA_DH_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029753">
        <property type="entry name" value="D-isomer_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029752">
        <property type="entry name" value="D-isomer_DH_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00389">
        <property type="entry name" value="2-Hacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00065">
        <property type="entry name" value="D_2_HYDROXYACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00671">
        <property type="entry name" value="D_2_HYDROXYACID_DH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2-Hacid_dh" evidence="4">
        <location>
            <begin position="3"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="domain" description="2-Hacid_dh_C" evidence="5">
        <location>
            <begin position="108"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV58197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="321" mass="34263" checksum="1CEB3F51101A47F8" modified="2019-10-16" version="1">MKVFVTRQIPDAGLDRIRTACDCDVWPEPLPPSRDQLLEKSAGCDGVLTLLSDRIDAEFFDRVGPQLKVVSNFAVGYNNIDVAEAARRGIAVGNTPGVLTDATADIAVGLLLAAARRMREGIDNVTNQQWKTWEPMGFIGQDLVGKTIGIVGMGRIGAAVARRLHFGWGMSVVYTSRSDKPELDSELNARRVAFSQLLSDSDFVSIHTDLNPATEKLFNDSAFAKMKPTSVLINTARGGIVDQDALHQALQSGTIFSAGLDVTEPEPLPVSSPLRSLGNCVILPHIGSGTVASRDAMATIAADNLLAGLAGKPLPHRVDPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYP8</accession>
    <name>A0A518IYP8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Oligopeptide-binding protein OppA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">oppA</name>
        <name evidence="4" type="ORF">Mal33_42330</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial solute-binding protein 5 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030678">
        <property type="entry name" value="Peptide/Ni-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039424">
        <property type="entry name" value="SBP_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023765">
        <property type="entry name" value="SBP_5_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000914">
        <property type="entry name" value="SBP_5_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30290">
        <property type="entry name" value="PTHR30290"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00496">
        <property type="entry name" value="SBP_bac_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002741">
        <property type="entry name" value="MppA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01040">
        <property type="entry name" value="SBP_BACTERIAL_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="SBP_bac_5" evidence="3">
        <location>
            <begin position="85"/>
            <end position="568"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV58216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="651" mass="73853" checksum="0643D65F09964ADB" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYY1</accession>
    <name>A0A518IYY1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Peptide zinc metalloprotease protein YydH</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">yydH</name>
        <name evidence="5" type="ORF">Mal33_43140</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001193">
        <property type="entry name" value="MBTPS2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13325">
        <property type="entry name" value="PTHR13325"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="136"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="233"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="262"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="337"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="369"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="411"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="domain" description="HlyD_D23" evidence="4">
        <location>
            <begin position="429"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="515"/>
            <end position="542"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV58296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="684" mass="75477" checksum="B55901E473F1DF8B" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ01</accession>
    <name>A0A518IZ01_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type II secretion system protein G</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">xcpT_13</name>
        <name evidence="2" type="ORF">Mal33_43250</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011453">
        <property type="entry name" value="DUF1559"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07596">
        <property type="entry name" value="SBP_bac_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="170"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="332" mass="36192" checksum="B65DF653C92DB9D6" modified="2019-10-16" version="1">MKRSRSGFTLVELLVVIAIIGILVGLLLPAVQAAREAARRMQCSNNLKQIGLALHNYHDTYKKFPAAWLSNKGEAGVKTTDKSYWGWGASILPFVEQQPLFDALQVGTIKLHDAANTPELLALMQTPLAAFRCPSDIAPDFNTHTERKLHSGLGGASDAQIATSNYVASNDTWEPRDDPRAGEKGPFEENDNASFRDIIDGTSNTIAVGERRWQHRAPNGNLRIEAAGTVFGIGDKKNTGWTSAVVGTGIVKMNTLQDSWRCQQGFSSVHPGGAMFVFCDGSVHFVGDTVEFEMNAETDVASANYQMNLHGGYDNVYNKLIARDDGRPVVLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ42</accession>
    <name>A0A518IZ42_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_43670</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008323">
        <property type="entry name" value="UCP033563"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36454">
        <property type="entry name" value="PTHR36454"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06245">
        <property type="entry name" value="DUF1015"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="435" mass="48121" checksum="B385E93708216E1E" modified="2019-10-16" version="1">MPEISAIRALRYNLGHVGNLSDVVAPLADAIDPQRQDILYKRHPASCVRLIANRDEPGDVAGSSDERAARFWRRWQSEGVLQHEAAAEIYIYQQTYPDGDQTVRRRGILCGVRFDSPEDRRLYTATETIDAVVEARYELTRRCAANLSPIVGLCSDPDDRLQDLLDSAIQEGLEITCVDDAGVRHSIWPINDERTIGSIQNILGPSPVLIAAGEDNLAASRKYLNWLNDHEGPVANDHPANFALTLLLRLEDSGDLLDSTHRVVRGGAPLTSEELVARIGECFTCNTIVEGPDAAEVAWTPISGRDHQGRLAIYCGGDRRWVLCEANEAATERLRKRCPQASDEWCELSINLLHHLIIPELLAEDSPSIQECRTIDDVVAAISDDEGCRFAALIPPIDVDAMETIAVQEERLPANAFHLAHAPLTGLVFNPLNRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ92</accession>
    <name>A0A518IZ92_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">S1 motif domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_44200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.650">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023319">
        <property type="entry name" value="Tex-like_HTH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018974">
        <property type="entry name" value="Tex-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032639">
        <property type="entry name" value="Tex_YqgF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037027">
        <property type="entry name" value="YqgF/RNaseH-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09371">
        <property type="entry name" value="Tex_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16921">
        <property type="entry name" value="Tex_YqgF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="SSF47781"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S1 motif" evidence="2">
        <location>
            <begin position="958"/>
            <end position="1027"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="189"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="799"/>
            <end position="903"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1025"/>
            <end position="1243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="312"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="332"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1035"/>
            <end position="1053"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1103"/>
            <end position="1124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1214"/>
            <end position="1228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1243" mass="132389" checksum="5AAAFD0ECAC16CA9" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZL9</accession>
    <name>A0A518IZL9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Translational regulator CsrA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">csrA</name>
        <name evidence="4" type="ORF">Mal33_45600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CsrA/RsmA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048027">
        <property type="term" value="F:mRNA 5'-UTR binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044781">
        <property type="term" value="P:bacterial-type flagellum organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006402">
        <property type="term" value="P:mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045947">
        <property type="term" value="P:negative regulation of translational initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902208">
        <property type="term" value="P:regulation of bacterial-type flagellum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006109">
        <property type="term" value="P:regulation of carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.4380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00167">
        <property type="entry name" value="CsrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003751">
        <property type="entry name" value="CsrA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036107">
        <property type="entry name" value="CsrA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34984">
        <property type="entry name" value="PTHR34984"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02599">
        <property type="entry name" value="CsrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117130">
        <property type="entry name" value="SSF117130"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00202">
        <property type="entry name" value="csrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1005">Bacterial flagellum biogenesis</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0810">Translation regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV58537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="73" mass="8183" checksum="427CAFA0BC8CEE46" modified="2019-10-16" version="1">MLVLSRHRDESIMIGDDVVVTIVDIRGDKVRLGIDAPQSIPVHRQEVYDAIQRENQRASQLGTDATKSVRGQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZT4</accession>
    <name>A0A518IZT4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative FAD-binding dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_46300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008734">
        <property type="term" value="F:L-aspartate oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005288">
        <property type="entry name" value="NadB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42716">
        <property type="entry name" value="PTHR42716"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="567" mass="61939" checksum="C6917C37E76C34EC" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZX1</accession>
    <name>A0A518IZX1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Mce related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_46620</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003399">
        <property type="entry name" value="Mce/MlaD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02470">
        <property type="entry name" value="MlaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="domain" description="MlaD" evidence="2">
        <location>
            <begin position="38"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="404" mass="44658" checksum="B3BA49EFA8A51DA0" modified="2019-10-16" version="1">MDDRRLEFGVGVLVLASIGVSIILMFIFGAYPVLLKKEYPITANFPTVAGIDVDTPVVKFGYPIGRVTKIQLGAEGVDVMMMIDAKYPIHKNEIPRIGSQRLVTGEARIEFVKANEKQLLELFDGKVNDPPDGILQPTESAFAQEYVPEDGYYVRVTDGVSSDPFAVLMSLEGEFRGTLKSIEDAGKSVDSLASQLESNVKTLFKGDGTQVHQIAQQTSQTLEQVRSTAAEVESILKDTQMKEKLKASLDRFPLLLDDAQETMHVAQRAIQSFENVGDSVNDTVKSVDRTVRNIERFTTPLADNSDELVANVLRSLNNLDQVLVQVAYFTEQLNEGDGTIKRLIEDDELYWQVRRIAGNIENLTARVRPIVDDARVFADKIARDPGTLGVRGALSRRPQGAGLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZY6</accession>
    <name>A0A518IZY6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase</fullName>
            <ecNumber evidence="3">2.7.7.60</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">4-diphosphocytidyl-2C-methyl-D-erythritol synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">MEP cytidylyltransferase</fullName>
            <shortName evidence="3">MCT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 4" type="primary">ispD</name>
        <name evidence="4" type="ORF">Mal33_46660</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>2-C-methyl-D-erythritol 4-phosphate + CTP + H(+) = 4-CDP-2-C-methyl-D-erythritol + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:13429"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:57823"/>
            <dbReference type="ChEBI" id="CHEBI:58262"/>
            <dbReference type="EC" id="2.7.7.60"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 2/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.60" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00056">
        <property type="reaction ID" value="UER00093"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050518">
        <property type="term" value="F:2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019288">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02516">
        <property type="entry name" value="CDP-ME_synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00108">
        <property type="entry name" value="IspD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001228">
        <property type="entry name" value="IspD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034683">
        <property type="entry name" value="IspD/TarI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01128">
        <property type="entry name" value="IspD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00453">
        <property type="entry name" value="ispD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="2 3 4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3 4" id="KW-0808">Transferase</keyword>
    <feature type="site" description="Transition state stabilizer" evidence="3">
        <location>
            <position position="22"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="3">
        <location>
            <position position="29"/>
        </location>
    </feature>
    <feature type="site" description="Positions MEP for the nucleophilic attack" evidence="3">
        <location>
            <position position="160"/>
        </location>
    </feature>
    <feature type="site" description="Positions MEP for the nucleophilic attack" evidence="3">
        <location>
            <position position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV58642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="231" mass="25451" checksum="A9E22EE95AC5522F" modified="2019-10-16" version="1">MDATLEPGSVAVILPAAGTSRRFGGPQSKIFATLAGHPVWWHAANRLRSFAEVGQIVIAIHPDDRPRWESEFADAVASLRIDLVDGGGERYESVLRAIERIEGASFIAVHDAARPLVSQTDLQRLFNAAATRDAVMLATPVRGTIKRADDDSIVQTTVDRSRLWEAQTPQMFRRELLIDAYARWRGWPVTDDASLVERSGGKVFLVEGSPLNLKITGPDDLLLAEAIMQQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0A4</accession>
    <name>A0A518J0A4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Endo/exonuclease/phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_48010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="SSF56219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021894399" description="Endo/exonuclease/phosphatase domain-containing protein" evidence="1">
        <location>
            <begin position="29"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="domain" description="Endo/exonuclease/phosphatase" evidence="2">
        <location>
            <begin position="37"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="270" mass="29659" checksum="EC43610F291E3AB5" modified="2019-10-16" version="1" precursor="true">MFPDQPLRWLLSFVLLCCLANTPVQLSAQSPTTLRVLSYNIHYGQGTDGVYDLERIARVIVAAKPDVVALQEVDVTVQRSGKVHQAQRLAELTGMAVRYGPTQHYQGGLFGNAVMTRMPIEDVRIQPLPYTDATEQLTTYPRGAIAVVVQSPQGQPVRFISTHFQHNVPDDRVAEADAINGFFATDNVPTVLAGDMNAVPGSKPIEILESRWKNAIDGEAAPSAPSPKPTVRIDYIFYRGETLKMVHSEVIDDGLASDHRPVLAVFELAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0C7</accession>
    <name>A0A518J0C7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Auracyanin-A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Mal33_48070</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000923">
        <property type="entry name" value="BlueCu_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028871">
        <property type="entry name" value="BlueCu_1_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002327">
        <property type="entry name" value="Cyt_c_1A/1B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013427">
        <property type="entry name" value="Haem-bd_dom_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11961">
        <property type="entry name" value="PTHR11961"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00127">
        <property type="entry name" value="Copper-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="SSF49503"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="SSF51658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02603">
        <property type="entry name" value="CxxCH_TIGR02603"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00196">
        <property type="entry name" value="COPPER_BLUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="3 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021917461" evidence="7">
        <location>
            <begin position="26"/>
            <end position="1514"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="8">
        <location>
            <begin position="512"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="281"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="471"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="476"/>
            <end position="497"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV58782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1514" mass="167135" checksum="E3D4434E0200EF4E" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0D9</accession>
    <name>A0A518J0D9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Photosynthetic apparatus regulatory protein RegA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">regA</name>
        <name evidence="3" type="ORF">Mal33_48290</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002197">
        <property type="entry name" value="HTH_Fis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02954">
        <property type="entry name" value="HTH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01590">
        <property type="entry name" value="HTHFIS"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="30"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="209" mass="22793" checksum="30C760BE81E01DEB" modified="2019-10-16" version="1">MTDPMSSASIDSDAEAITRGLDAETLGVSSIIVVDDTFVLRDRLSLAFQQRGFRVEQAGDYDEAIARFSSRPTDLAVIDLRMPGRSGLDLLISIKRIHPETKVVILSGFGSIAAAIDAVRMGATNFLSKPADVDDILNAFVRGDQPQSHASDGTEFPVPSLARAEWEHIHRVLSDCSGNISEAARRLGIHRRSLQRKLRKRAPDDPGSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0H0</accession>
    <name>A0A518J0H0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Multidrug resistance protein MdtK</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">mdtK</name>
        <name evidence="2" type="ORF">Mal33_48530</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006603">
        <property type="entry name" value="DinF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00797">
        <property type="entry name" value="matE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="159"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="189"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="284"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="315"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="362"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="391"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="422"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="463" mass="49749" checksum="361B7B09ED64BC64" modified="2019-10-16" version="1">MNIWNRPAGIAEVLRVALPLMISTGCFTLTLFSDRTLLLWYGQPEMAASMAGGNLFWTLTCFPVGIVSMTSAMVAQYAGSGQPQRIGRLIWQAIWLTLAVSPLLWMLIPMSRSIFIAAGQDPSLLDLETIYLQWLLVGASAVVLESALAGFFSGTERTAIVMWVNVVASILNLVLDVVLIFGYAGFPELGIVGAGIASSVSFWAKAIIYFVLMHRRCDTERYGIAAGRCFDWVLCRRLLFFGVPAGLQYQAESGGFAMIVLQIGQVGTDALAATAMAINFNMAAFVPLIGVSIAASVLVGKHLTESGPVLASRAAVSAALLGVCYSAAWAASYVLIPDTLLSLYLAGNQGEAIASTIALAKVLLRFVAVYCIFDAAQIVIAGALRGAGDTWFVLYASVSVAVTWVVVGLIGKGYSSDPLYWWWWMLTCWVMSMAAAMLGRFAHGRWRTLRMVDANEPTAAAVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0I2</accession>
    <name>A0A518J0I2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_48810</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="84" mass="9392" checksum="94F5F3F4A1445AE0" modified="2019-10-16" version="1">MDNHLHVLCKLDPEATDRWSPQQVVRRWITIYPSKTLKSNDEKLSGSLSKARRAIHGGSGRHRPRVDRFSHLRSVFTASGGAGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0P5</accession>
    <name>A0A518J0P5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_49340</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011473">
        <property type="entry name" value="DUF1579"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07617">
        <property type="entry name" value="DUF1579"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="157" mass="17890" checksum="A6356556C41A8789" modified="2019-10-16" version="1">MFAKPQQEHRWLDRLVGNWAFEHHCEMPDGTKSATEGKMVCRSLEGMWLICESSGIFDDGQPWSSIMTLGFDVKQNRYVGSFIGSMMSNLWLYQGDLDDAGKRLPLQSIGPTFAGTGTCKYRDTIEIVDADNWLFTSELQTEAGEWVKFMDAPHRRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0U0</accession>
    <name>A0A518J0U0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_49820</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010869">
        <property type="entry name" value="DUF1501"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07394">
        <property type="entry name" value="DUF1501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="469" mass="51191" checksum="130AB76D6A299548" modified="2019-10-16" version="1">MNLARREFFETAGIGLGSLALNAMLGDEVSASGSASSFSQQPHFPPTVKSVIFLFMSGGPGHMDTFDPKPLLSEMDGEYVPESIAATVPNIPRAGVGSKLMASPFGFKKYGESGIEVSELLPHTAKHVDDLCVIRSLNHRIPVHGPGENFTLTGSSLGERPSLGGWVTYGLGSEARDLPGFIVLSSNSSGPAPQRPGWGSGFLPARFQGTQIDNQRGVPYSELPDLYSVDDRRDQLDFIRSMNQQHLRRQDLNTELEARIESYELGFRMQLNAPEILDLSGETEATQRMYGIDQKASKQFGSHCLLARRLVEQGVRFIQLRNGGWDAHGALKGNHINRCRATDMPVAGLLQDLKQRDLLDQTLVVWGGEFGRTPTTEGNRTGDSRGRDHSPAGYTMWMAGGGIKGGQVIGATDELGYVPIERPLSPHDLHATMLHGLGLDQHKLIYRHNNREEIATVLGGEVIHEAFAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0X2</accession>
    <name>A0A518J0X2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Oligoendopeptidase F</fullName>
            <ecNumber evidence="6">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">pepF1</name>
        <name evidence="9" type="ORF">Mal33_50180</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Has oligopeptidase activity and degrades a variety of small bioactive peptides.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6">Binds 1 zinc ion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the peptidase M3B family.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="6"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1370.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013647">
        <property type="entry name" value="OligopepF_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042088">
        <property type="entry name" value="OligoPept_F_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045090">
        <property type="entry name" value="Pept_M3A_M3B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001567">
        <property type="entry name" value="Pept_M3A_M3B_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004438">
        <property type="entry name" value="Peptidase_M3B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11804">
        <property type="entry name" value="PTHR11804"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01432">
        <property type="entry name" value="Peptidase_M3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08439">
        <property type="entry name" value="Peptidase_M3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00181">
        <property type="entry name" value="pepF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1 6" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase_M3_N" evidence="8">
        <location>
            <begin position="112"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M3" evidence="7">
        <location>
            <begin position="201"/>
            <end position="581"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU368091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV58993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="595" mass="68154" checksum="3353EE75CE2D569B" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J194</accession>
    <name>A0A518J194_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_51350</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="139" mass="14270" checksum="B50F442EE2A3AB6B" modified="2019-10-16" version="1">MSRCFLVTVALTLMISGCGPDTGGRVGVTGTVTFQGQPLDSGNIQFDAVDGSGMTGAAITDGKYSVPAETGVIPGEYTVRVSKAGDDAAAPKPVAGEAPGDPGAFSPREEMIPEEYNLQSKLTTQLTADKANVYDVDIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J196</accession>
    <name>A0A518J196_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative major pilin subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_51360</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011453">
        <property type="entry name" value="DUF1559"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07596">
        <property type="entry name" value="SBP_bac_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="308" mass="34111" checksum="9D20AFE951DB2F65" modified="2019-10-16" version="1">MKRKSGFTLVELLVVIAIIGILVGLLLPAVQAAREAARRMQCSNNLKQIGLSMHNYHDTYQSFPAGNWGWGWGSWVVATLPYIEQDNLYQLYNQGNKFDIPNSSGRYSSTVNRQVTEQRLSAHTCPSDLPNVYSNMTLHNYGANFGNTGLDSANGYKQLASLNGVQYNGAPFEIILQGEASKMKKFRDIIDGTSNTFMFGEILQGQGTDLRGLTWWGLNNNFTTYLPPNTSLPDRMHSTSYFENKPVLKLPCALATTANPIMFAARSRHPGGVQVSRCDASVRFISETIDLNSYRAMSTTQGGEVISE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1A5</accession>
    <name>A0A518J1A5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Redoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_51500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013740">
        <property type="entry name" value="Redoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08534">
        <property type="entry name" value="Redoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022222476" evidence="1">
        <location>
            <begin position="27"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="2">
        <location>
            <begin position="39"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV59124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="197" mass="21062" checksum="1CF0DE841F2AA5BC" modified="2019-10-16" version="1" precursor="true">MRILQQMNAFCVMTLIAFSISASVQAESPAPVQAAKKALAVGQTAKDFQLLSVGGELSGEVKLSDVNADGKVVVVVLRGFPGKQCPACSAQVGDFVKNASKFAAKNAKVLLVYPGPKSQLDQRADEFLQGTKLPAPLTFLLDPGYTFTNAYGLRWDAPRETAYPTTLVLDESGKIQFVKISETHRGRSSAAEVLEAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1I4</accession>
    <name>A0A518J1I4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_52130</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="83" mass="8701" checksum="05CB9BE04C42E226" modified="2019-10-16" version="1">MPFSAIAFGSSTAAQSGFTSGIAPIGAIRSDRELPPQSPVCPPPMVSDDKVSLTGTTIVGEVEFAAMRPEKLNSLVPVRLRFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1J0</accession>
    <name>A0A518J1J0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Galactitol-1-phosphate 5-dehydrogenase</fullName>
            <ecNumber evidence="2">1.1.1.251</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">gatD_1</name>
        <name evidence="2" type="ORF">Mal33_52230</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.1.251" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008868">
        <property type="term" value="F:galactitol-1-phosphate 5-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ADH_N" evidence="1">
        <location>
            <begin position="27"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="368" mass="40158" checksum="7A93693BB9BCBB90" modified="2019-10-16" version="1">MQNSIYYLDKPGGTFTLAQESIGEPGPGEVRLRTSKTSVCQSDVVIYNVGLPRILSWPAILLHEVACIVDAVGPGVEKFSPGDLVGLGCDIPCGDTECIYCGTSGTGDWTSCPNTQATGHEFPGFARSHAILPKWFVDDGPIVKFPTGFNPNHACQLEPLACCLEGMTRVNNCIENRIVVLIGAGSQSTYALQCAQAMNAKKIILINRGKERLERVLADFGDDRVVGVRWDENVVENTLAHCKPYNEPHFVMVNAPVREAYDLAPKLMGYGTVLDGHAGVKGADGKPRIAHEIDLNNDIHYRLQCYQATHGSSMHGIRLAHKFLSEGLLPNIDKMTNETEVFAQDQIPAAIARAADKDSLKVIIDWDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1L8</accession>
    <name>A0A518J1L8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Iron(II)-dependent oxidoreductase EgtB</fullName>
            <ecNumber evidence="3">1.8.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">egtB</name>
        <name evidence="3" type="ORF">Mal33_52590</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.8.-.-" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052699">
        <property type="term" value="P:ergothioneine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024775">
        <property type="entry name" value="DinB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017806">
        <property type="entry name" value="EgtB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005532">
        <property type="entry name" value="SUMF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042095">
        <property type="entry name" value="SUMF_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12867">
        <property type="entry name" value="DinB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03781">
        <property type="entry name" value="FGE-sulfatase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="SSF56436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03440">
        <property type="entry name" value="egtB_TIGR03440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DinB_2" evidence="2">
        <location>
            <begin position="25"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="FGE-sulfatase" evidence="1">
        <location>
            <begin position="220"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="domain" description="FGE-sulfatase" evidence="1">
        <location>
            <begin position="364"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV59231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="439" mass="49732" checksum="3C806C751153BC3A" modified="2019-10-16" version="1">MNLATSNGDAFAEPSVDLSELADAFRNARAFTARLCEPLEIEDMVAQSMPDASPVVWHLAHTTWFFETFLLKPFCPGYKPFHPQFEYLFNSYYNAVGEQFTRADRGLLTRPTVAQVRRYRESVEGCVNEFLAAGRFDDAAAVRGTVELGIQHEQQHQELILTDLKHLLSRNPLAPAYRSLPDAIESSDGMMTESSVATAAPIRFVDFPEQLAWIGYDGDEFAFDNERPRHRQFVDAFGIANRLVTNGEYLAFMEAGGYNRPEYWLSMGWSAVCENRWQSPLYWTQRDGRWCEFTLDGIQSLQMDAPVCHISYFEADAYARFAGLRLPTEAEWEIVASQTPVEGHFAESLRLHPDPAAGSSPIDQMFGDCWQWTSSPYIGYPGYRPPSGAIGEYNGKFMCNQYVLRGGSVATSRSHIRASYRNFFPPQARWQFTGIRLAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1P3</accession>
    <name>A0A518J1P3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Competence protein A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_52830</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005883">
        <property type="entry name" value="PilM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11104">
        <property type="entry name" value="PilM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01175">
        <property type="entry name" value="pilM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="745" mass="83574" checksum="E067B4CE87268C7B" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1V1</accession>
    <name>A0A518J1V1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Polysaccharide pyruvyl transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_53420</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007345">
        <property type="entry name" value="Polysacch_pyruvyl_Trfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04230">
        <property type="entry name" value="PS_pyruv_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PS_pyruv_trans" evidence="1">
        <location>
            <begin position="45"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="414" mass="45391" checksum="DBFD05D8C6F39077" modified="2019-10-16" version="1">MLKSILKSVASESINSLGRTKRLFTNRPDKVPQVGLLVPAWQGSLGDEAVITAATEFLKRDRNAEVTLIGFDRGAPWNSIKLIDHRIGIPDFFTTGGWPERRRMTSQFCKFDQFFLLGTDMLDGHYTDWHSSGLLTIARQAAMSGIPTNAVGFSLKDCPAEQAIQGLRALAACRSTTMCIRDQVSLTRYKKFVAGNAELTADPAFLLEPDASKHGARSWVRSQSSEGNLCLGLNLSSHVYDSLSESEQTAILVAIRDSILALAEKSKPISVLLIPHDIRIDFDDVRLCKLVQHAIHDLPGVESYVMQTPYSPGIIKSIVAELDFVLSSRMHLAIACLGAGTPVGCITYQGKFEGLYQHFGISDCTISPEDAMSSPNLTEFLIQRVLTRASIASRIADSIPGVTRLAQRNFEFTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ILW1</accession>
    <name>A0A518ILW1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Blue-light-activated protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Mal33_00270</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007891">
        <property type="entry name" value="CHASE3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05227">
        <property type="entry name" value="CHASE3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAS" evidence="5">
        <location>
            <begin position="226"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="5">
        <location>
            <begin position="348"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="6">
        <location>
            <begin position="420"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="3">
        <location>
            <begin position="485"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="728"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="779"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV54086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="845" mass="92928" checksum="C3C0CE7D02516113" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IM32</accession>
    <name>A0A518IM32_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Glutamine--fructose-6-phosphate aminotransferase [isomerizing]</fullName>
            <ecNumber evidence="2 8">2.6.1.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">D-fructose-6-phosphate amidotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">GFAT</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Glucosamine-6-phosphate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Hexosephosphate aminotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">L-glutamine--D-fructose-6-phosphate amidotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 11" type="primary">glmS</name>
        <name evidence="11" type="ORF">Mal33_00670</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>D-fructose 6-phosphate + L-glutamine = D-glucosamine 6-phosphate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:13237"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58725"/>
            <dbReference type="ChEBI" id="CHEBI:61527"/>
            <dbReference type="EC" id="2.6.1.16"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.6.1.16" evidence="2 8"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004360">
        <property type="term" value="F:glutamine-fructose-6-phosphate transaminase (isomerizing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901137">
        <property type="term" value="P:carbohydrate derivative biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05008">
        <property type="entry name" value="SIS_GlmS_GlmD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05009">
        <property type="entry name" value="SIS_GlmS_GlmD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00164">
        <property type="entry name" value="GlmS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035466">
        <property type="entry name" value="GlmS/AgaS_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035490">
        <property type="entry name" value="GlmS/FrlB_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005855">
        <property type="entry name" value="GlmS_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001347">
        <property type="entry name" value="SIS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10937:SF0">
        <property type="entry name" value="PTHR10937:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01380">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01135">
        <property type="entry name" value="glmS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51464">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8 11" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 8 11" id="KW-0808">Transferase</keyword>
    <feature type="initiator methionine" description="Removed" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="9">
        <location>
            <begin position="2"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="domain" description="SIS" evidence="10">
        <location>
            <begin position="297"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="domain" description="SIS" evidence="10">
        <location>
            <begin position="468"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile; for GATase activity" evidence="8">
        <location>
            <position position="2"/>
        </location>
    </feature>
    <feature type="active site" description="For Fru-6P isomerization activity" evidence="8">
        <location>
            <position position="614"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QDV54123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="619" mass="67865" checksum="D29B1E6F00427CC9" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IM55</accession>
    <name>A0A518IM55_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_01290</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="13"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="190" mass="21816" checksum="E4226952EDBD806E" modified="2019-10-16" version="1">MWPTITRLSFQSELPMAAQQRRPIELKRRCGRQPPKGSNRKQPEYAVTDIEPTLPATHRLHLARCPGLLAYPRPNRPHQVRGSESERGTSGFCTKRYERSGWNAGMEDPQCCWSEAVGRRPYGSSPANREQCSSVSLRLWGHLKSLTRSRLIEHADGTSLRQSELMLKRCHCRAARLRGRRLPLVIYFII</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IM65</accession>
    <name>A0A518IM65_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Zinc carboxypeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_01390</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004181">
        <property type="term" value="F:metallocarboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040626">
        <property type="entry name" value="Pepdidase_M14_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000834">
        <property type="entry name" value="Peptidase_M14"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18027">
        <property type="entry name" value="Pepdidase_M14_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00246">
        <property type="entry name" value="Peptidase_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022156522" evidence="1">
        <location>
            <begin position="25"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="domain" description="Pepdidase_M14_N" evidence="3">
        <location>
            <begin position="31"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M14" evidence="2">
        <location>
            <begin position="160"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00246"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF18027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV54190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="418" mass="46307" checksum="7516D8DD552E84D2" modified="2019-10-16" version="1" precursor="true">MNPRQLLVPLAFLSLAIAGEQLFADDPLSVAADFEGGSVAEVEIDPAAGSIRFMPGGDPARGWPCWWYFRIDGIQPGQTITLQLRGSTATVGKQKPLGASWAMPKRATYSTDGKTWRQTDPGQRDGHIMTYKLTPDASSVYVAWGPPYTPKTAERLATRLSEASPHVEAMQLCRSREDREVPMLHFHEGTRAAEQRFGVWIQARQHAWESGSSWVAEGFADWLAGDDPQAAWLRQHADVYLVPIMDIDNTATGNGGKNAIPRDHNRDWSAEPHWNEILAAQQKVGELIDQNRMDLFIDLHNPGPGDSTFFFVPSRELLKPQAADSTDDFMELAHQRISSIKPSIPMSNKPRVTGSTYHPLWRQISTNWVSLNGNPNTVSVCLETAWNSPTSTPTGYKAVGENLAIATQQFLAKQPKKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMC5</accession>
    <name>A0A518IMC5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">pyrK</name>
        <name evidence="6" type="ORF">Mal33_01860</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
        <text evidence="4">Binds 1 [2Fe-2S] cluster per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PyrK family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006221">
        <property type="term" value="P:pyrimidine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.240.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008333">
        <property type="entry name" value="Cbr1-like_FAD-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012165">
        <property type="entry name" value="Cyt_c3_hydrogenase_gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037117">
        <property type="entry name" value="Dihydroorotate_DH_ele_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019480">
        <property type="entry name" value="Dihydroorotate_DH_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10418">
        <property type="entry name" value="DHODB_Fe-S_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00970">
        <property type="entry name" value="FAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006816">
        <property type="entry name" value="Cyc3_hyd_g"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="SSF52343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="3" id="KW-0249">Electron transport</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="5">
        <location>
            <begin position="14"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="252"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="257"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="260"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="277"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR006816-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV54236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="290" mass="30576" checksum="70F484965197772A" modified="2019-10-16" version="1">MTSPLHAQHYADCAASLRAVVTASDLIAEKTYRLRLHAPEIACQIVPGQFVMIRLDGFNDPLIGRALAVYRVVANGDQPPEELEVVYIAKGKLTTRLARIQIGQHIGIWGPLGNGFPTVECEHLIMAAGGIGQTPFLALGSEALGRESFPGRTSGYAARATLLYGVRSASLAAGLDDFAAAGIDLDLCTDDGSLGTQALVPDRLATLLAAPDRAASTRVVCCGPEIMMQRVAEVCAAAGVPCTVSLETPMACGIGICFSCVAKVRQADGEWDYKRTCVEGPVFDAASVVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IME3</accession>
    <name>A0A518IME3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Molybdopterin molybdenumtransferase</fullName>
            <ecNumber evidence="5">2.10.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">moeA</name>
        <name evidence="8" type="ORF">Mal33_02090</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 5">Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>adenylyl-molybdopterin + H(+) + molybdate = AMP + H2O + Mo-molybdopterin</text>
            <dbReference type="Rhea" id="RHEA:35047"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:36264"/>
            <dbReference type="ChEBI" id="CHEBI:62727"/>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.10.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 5">Belongs to the MoeA family.</text>
    </comment>
    <dbReference type="EC" id="2.10.1.1" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00344"/>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061599">
        <property type="term" value="F:molybdopterin molybdotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032324">
        <property type="term" value="P:molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00887">
        <property type="entry name" value="MoeA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.340.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.980.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036425">
        <property type="entry name" value="MoaB/Mog-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001453">
        <property type="entry name" value="MoaB/Mog_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038987">
        <property type="entry name" value="MoeA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036688">
        <property type="entry name" value="MoeA_C_domain_IV_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005110">
        <property type="entry name" value="MoeA_linker/N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036135">
        <property type="entry name" value="MoeA_linker/N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10192">
        <property type="entry name" value="PTHR10192"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00994">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03453">
        <property type="entry name" value="MoeA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00852">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53218">
        <property type="entry name" value="SSF53218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63867">
        <property type="entry name" value="SSF63867"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63882">
        <property type="entry name" value="SSF63882"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 5" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="5" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MoCF_biosynth" evidence="7">
        <location>
            <begin position="181"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="380"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU365090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV54259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="401" mass="42704" checksum="E2118EA5E12A56DC" modified="2019-10-16" version="1">MIEKSEKTPDQAIAELAGRIAPVASETISLANASGRILSQPIHADRDSPAADVSAMDGYAIRLDDLGRDEPLPVSGEIAPGHPTPDVQPGHAMRVFTGGIVPQDYDLVVKREETQESPESIRLLPATANCRKGENIRRQGENASQGSAILQAGTTLHAGAIAATANFGASEVHVSRVLKITILVTGDELHDVDAEVQPWQLRDSNGPTLNALLSGKNWLHVRCVDRVVDNQQGLAERLAAAIEDSDAVILTGGVSMGDYDFVPDAIGQNDGEVIFHRLPIRPGKPILGAVTAAGKPIIGLPGNPVSAAVGCRRFVLPLLSRQAGKRDWLPPAPRVMLDDPGTRTLPLHWFRLVQIDDQGGVSLVPSKGSGDLVSMAASDGFTEQPPNSTGPGPWPFWRWQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMF6</accession>
    <name>A0A518IMF6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_02210</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021980949" evidence="2">
        <location>
            <begin position="25"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="245"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="355" mass="39032" checksum="0A1D2045FB3B3DAC" modified="2019-10-16" version="1" precursor="true">MHSTLKLNALLFAAIVGVTEPAVAARPASIQFDLSPVASAQPVVPDEDAFVPPGHRWVRVRLDISSMINTAEQAKPHEFVYRIQCSSLDSRVVDYSPRTQLAASTVGGIRVEQSDEKSKSLGLALKGSYLNLVDGSSGADVGSKVCNKTTFEKAAPQEIMYASGTIARGQGVYFKLRATPAQVLDGQKPFTITLQVPDKWRGDLLSVHLSATESQRSFGALDRDTVQSSPARFQVAVFDQSDDIARRWAWQLAEAEQRLRESSQQYASSIRERSLPTIFHHVAAALDVIEPRISEDWMQRALYGSIDPYFDKQIRQLPVAVKVAVLDYVDAKTNFQGLVRSQSLSQEARSGLAVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMH0</accession>
    <name>A0A518IMH0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_02150</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="158" mass="17288" checksum="773BE948D0DC1CF4" modified="2019-10-16" version="1">MRCVWLLCESGNRWRPAVDHFAVQMLPAADDVLEIRSIASPEACLTALAQQVPAVVLWELPAAGAGPVLESISRAATRGANRPLQFVALSQESIVPSGIAGEVELNLRELGVAGVVDRPVSLANHAAMVRRYWQQSQRDDNLSAVREIWDRLPWAGDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IML9</accession>
    <name>A0A518IML9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Putative pre-16S rRNA nuclease</fullName>
            <ecNumber evidence="2">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">yrrK</name>
        <name evidence="4" type="ORF">Mal33_02910</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the YqgF HJR family.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000967">
        <property type="term" value="P:rRNA 5'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16964">
        <property type="entry name" value="YqgF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00651">
        <property type="entry name" value="Nuclease_YqgF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005227">
        <property type="entry name" value="YqgF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006641">
        <property type="entry name" value="YqgF/RNaseH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037027">
        <property type="entry name" value="YqgF/RNaseH-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33317">
        <property type="entry name" value="PTHR33317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03652">
        <property type="entry name" value="RuvX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00732">
        <property type="entry name" value="YqgFc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00250">
        <property type="entry name" value="RNAse_H_YqgF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="YqgFc" evidence="3">
        <location>
            <begin position="15"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV54338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="171" mass="18581" checksum="A63A0EBA475BFB1C" modified="2019-10-16" version="1">MSDESPQPAPFPSQGRIAAVDYGTVRIGVAVCDPDRIIASPLTVVPQGAAEQRGKAFCQLAAEERITGWIVGFPIHLSGTESKKSIEARKFAKWLQQTTDLPVRLFDERFSTAAADQRLAPSKLTNKGRKKRIDAVAAQVLLESFIESARHRSDLPGLALDEKAIGDAIED</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMR8</accession>
    <name>A0A518IMR8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glucokinase</fullName>
            <ecNumber evidence="2">2.7.1.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">glcK_1</name>
        <name evidence="2" type="ORF">Mal33_03410</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.1.2" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004340">
        <property type="term" value="F:glucokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000600">
        <property type="entry name" value="ROK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18964">
        <property type="entry name" value="PTHR18964"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00480">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="323"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="328"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="350" mass="36834" checksum="A8BF3C800C151848" modified="2019-10-16" version="1">MADTDKKKWIGFDLGGTKMLAVVYDHDLKPLGRRRRRTKGNSGAESVIERIIGAIERAMEETDTKVEEIAGIGIGCPGPVDPNTGLVHVCVNLGWENVNIGKILHKQFGCPVHVLNDVDAGVYGEYVDGAAKKSRCTVGIFPGTGIGGGCVYEDTILHGADISCMEIGHTRISSGSRTSGYDLSGTLEAEASRLAIAAEAAKAAYRGMAPHLYKETGMDLSEIRSGALADSVKHGDTEVKELIEEASRTIGLAVVNIVHLLAPDTIVMGGGLVEAMPDLIIGTVTRTAKKSVLAPYKNRFRVVQAELGDDAAVLGAAAWARKRTPVAPTAAPEPPPAEPTPAEPNPPAAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMY7</accession>
    <name>A0A518IMY7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative major pilin subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_04110</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011453">
        <property type="entry name" value="DUF1559"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07596">
        <property type="entry name" value="SBP_bac_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="230"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="232"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="294" mass="32593" checksum="1FD665B99BA69937" modified="2019-10-16" version="1">MLIPRNKRRGFTLVELLVVIAIIGILVGLLLPAVQAAREAARRMQCSNNLKQIGLASHNFHDTFGYLPTGGSDGPFKTCCNSTVREGWSWLYQLTPFIEQNNVHELPTDSDVYSSLITSYVCPSRRPAQLWNGSFRADYAGNGGITTQTWQGPFVRQWKTLPLPSSTTNFNPDQTRRLDDIKDGTSNTLLVAEKQVHWSTFGTAGGDNEVWANAGWDQDIVRYGNFLPEPDNDHPDSTQSTHWSNRFGGSHPGGVQGVRADGSVVMIPYTVDAVNFQNFCTIRDGVALDEDIFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IN92</accession>
    <name>A0A518IN92_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Heat shock protein HtpX</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Mal33_05050</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001915">
        <property type="entry name" value="Peptidase_M48"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01435">
        <property type="entry name" value="Peptidase_M48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0346">Stress response</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="145"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="192"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M48" evidence="9">
        <location>
            <begin position="241"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="34"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="64"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV54550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="538" mass="58852" checksum="ECB9C55CC56C79D0" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INA9</accession>
    <name>A0A518INA9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_05250</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019903">
        <property type="entry name" value="RIC_family"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038062">
        <property type="entry name" value="ScdA-like_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04405">
        <property type="entry name" value="ScdA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140683">
        <property type="entry name" value="SSF140683"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="76" mass="8735" checksum="401F2265B7EBDBD7" modified="2019-10-16" version="1">MDCDLETTIPEWIIEHPETMPVFDQLGLDTSCGGKSLRYVCQHRGLNPSEVLQTLYHVIRTPPEERQGSRRRDAPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INB2</accession>
    <name>A0A518INB2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_05260</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="233" mass="26555" checksum="8F973523156D70B2" modified="2019-10-16" version="1">MRDIMGFLKRILRTGGPDTTTKEASPASFQQLSEDELRTHLGIATYGAFELTNAIRPSYDLQVVPRQGFRRDEYVDDASSTSVPVLMAAASRNNLMHLFMDLIESLGPVVDVVLETSHQSGQGHNDLYREHIDMPVLKSTLWDFEDLLLNDGCTGIAIVNPRRKQEVQFDEHKLLITYGDPLKDFEKSFIAHDVYPDADIRFVTEAEHVHSSNEKYQHQFEVLKTRLGMDDSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INC5</accession>
    <name>A0A518INC5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FG-GAP repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_05410</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.130">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013517">
        <property type="entry name" value="FG-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028994">
        <property type="entry name" value="Integrin_alpha_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13517">
        <property type="entry name" value="FG-GAP_3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69318">
        <property type="entry name" value="SSF69318"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="439" mass="47649" checksum="808478369E04FD75" modified="2019-10-16" version="1">MKGLMLIKSPMSQIAVLLLLILAVPLVAVYVPSVVGSLSPLPVVFQGGTTYPASSVQFDQVALDDTSVGLPQITNVQVLDFDGNGANEVLACDSLKNQVVLFRQVDGEWQEEVLVPDVAAPAHATAVDIDSDGDLDLVVSVLGNILPDDSVIGRVELFEATPDGYRRHVILDDVRRVADVQPADFDGDGDIDLAVAVFGYSRGSVLWLENRGELKFRDHLLHTAPGTIHVPIADYDGDGDLDIAAIVTQDEEELWGFENLGQGEFKKRRLWMTINHDLGSAGLVQADLDGDGDPDLILPAGDNLEDLDAYPQPYHGCYWFENQGDWTFQIHRISDLGGTYAADVGDFDSDGDLDVVLASMTNNWNRTDTASLVWLENDGQQNFTTWQIASDPIHLVTVAAGDLDGDGSDDIVAGALNLRKPFQRVSRVSAWINQGEGKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IND5</accession>
    <name>A0A518IND5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_05680</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="104"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="124" mass="12864" checksum="BD26587B629CBF34" modified="2019-10-16" version="1">MPHLAAILYAMIIIGVILFQCCLIAGAPWGPVTQGGQHPGALPAKGRVAALLSAALLAFMAAGITSAAGLAPHWQNWTGWAALGVQSLSTLLNWITPSRPERRLWGPVTSIMLGLATFAVVAGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ING9</accession>
    <name>A0A518ING9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_05930</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021975780" evidence="3">
        <location>
            <begin position="33"/>
            <end position="1086"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1046"/>
            <end position="1067"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="911"/>
            <end position="1000"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV54638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1086" mass="125064" checksum="1B566F0BC6911B1D" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INP7</accession>
    <name>A0A518INP7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">UDP-glucose 4-epimerase</fullName>
            <ecNumber evidence="2">5.1.3.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_06620</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="5.1.3.2" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003978">
        <property type="term" value="F:UDP-glucose 4-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="4"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="334" mass="35905" checksum="12AA058F144F1785" modified="2019-10-16" version="1">MRAIITGIAGFIGSHVATEMLQLGWDVTGIDDLSGGFAANVPEGARFVQRDCCSDLDDLFGEVKPDVVVHLAAYAAEGLSHHVPNFNYMNNLVGTSNVLSAASRFGARHFVFTSSIAAYGHPSTDSPLTEATACHPCDPYGIAKLACEQHIAAFRDYYGGPDFTIFRPHNVFGPQQNISDPYRNVMGIFFRCAKQGLPFPVFGDGSQSRSFSYVDVVAKCIAQSPGNAAAKNQVFNVGGDRAMSINELVDAVAKAAGVTATIDYLPARKEVLHAHADHAKARAAFPDVYRDAIDFEVGLKKMAAFVQQMDVPAPTPCPAPIEIVQQLPPSWKNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INR8</accession>
    <name>A0A518INR8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Arylsulfatase</fullName>
            <ecNumber evidence="5">3.1.6.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">atsA_5</name>
        <name evidence="5" type="ORF">Mal33_06880</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="PTM">
        <text evidence="1">The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.</text>
    </comment>
    <dbReference type="EC" id="3.1.6.1" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004065">
        <property type="term" value="F:arylsulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022100412" evidence="3">
        <location>
            <begin position="21"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase" evidence="4">
        <location>
            <begin position="26"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="157"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="171"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="modified residue" description="3-oxoalanine (Cys)" evidence="1">
        <location>
            <position position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR600917-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV54728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="476" mass="52971" checksum="6A5D2A57FD496632" modified="2019-10-16" version="1" precursor="true">MSTRFMLLLLLAMSQTTLWSEEPTKPNIILVMADDLGWGDVGFNGNSVIQTPHLDAMAKNGMRLTRFYTASPLCSPTRGSCLTGRHPWRFGVLAAHTGGMRRGEMTVAEVARLKKYQTGFFGKWHLGWVKPEEQLPRGYYSPPWHHGFDETFATTSAVPTWNPTQTPPEKSSGKKKGKKDSSKEPEPWKGGKPYVHNGVEVANNMEGDDSRVIMDRVLPFIRGAAQKQQPFLACVWFHTPHEPVIAGPEYRKLYPNNGTAKQNYYGAITAMDDQIGRLRDELRKLGIEKNTILFFTSDNGPSDSLAKKGVASAGPFRGHKHTMYEGGLRVPSVVEWPGQIAADTTSDTVCATVDYFPTVVELTGASLGKKADRPIDGQSLMGVLKGTATQRSTPLFFGYRRLYKDIDGQALVENRYKLLKRAVAGGEYELYDLAEDPAEENDLSATEPEILARMKARMAEYDESCRLSRDGADYQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INT9</accession>
    <name>A0A518INT9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Outer membrane biogenesis protein BamB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_07080</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025666">
        <property type="entry name" value="PQQ-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018391">
        <property type="entry name" value="PQQ_beta_propeller_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002372">
        <property type="entry name" value="PQQ_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13360">
        <property type="entry name" value="PQQ_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13570">
        <property type="entry name" value="PQQ_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00564">
        <property type="entry name" value="PQQ"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021948579" evidence="1">
        <location>
            <begin position="26"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="domain" description="PQQ_3" evidence="2">
        <location>
            <begin position="57"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13570"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="428" mass="46129" checksum="C9F8DF442C4A22F8" modified="2019-10-16" version="1" precursor="true">MDTRANRFLPIVLLLAGFGVSTATAAEPTWTQFRGADRAGIVPDAALPVQWDAKKNIRWRTELPGEGWSSPVTDGKRIYLTAAIPSDKAAAGEDASNGSFDLSLLIIDAETGELQTQQTLIHQTAEETQKIHAKNSHASPTTILDGDRLYSHFGFQGTVCTDLQGKTLWINRDLSFKAIHGNGGSPVLVDNRLVFTCDGASEPFVAALKTDTGELAWKCPRPVEAKKKFSFCTPAVIKVDGKQQIVAPGSNCVLGIDPADGSILWQVDYDGYSVIPQPVYAGGILIVCTSYDKGGLLAIDPRGRGNITETNVLWQLDKGAPKTPTPLMQSGLLYMINDAGVAYCLDAASGDRIWQKRIGGQYSASPLLADGKIYFTSEAGETTVIQASRDFQELARNDLGERTLASLAPLDSSILLRTAKALYRIETP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INY6</accession>
    <name>A0A518INY6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Outer membrane biogenesis protein BamB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_07630</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018391">
        <property type="entry name" value="PQQ_beta_propeller_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002372">
        <property type="entry name" value="PQQ_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13360">
        <property type="entry name" value="PQQ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00564">
        <property type="entry name" value="PQQ"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022152121" evidence="1">
        <location>
            <begin position="20"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="402" mass="42395" checksum="53EE6561510E7A86" modified="2019-10-16" version="1" precursor="true">MRTITFTACLLLIPMTAWGDDWLGFRGFGGRADSPQSNPPAEFSAEEGKNIAWRAETVGRGIAGPLVVGDLVIATSCGGIDERDISVEAFDAATGKRVWVRTLLALGRPFTHPTSANAAPTPASDGEKIFALYSSCDLVCLDREGGIVWYRGLGVDHPKTGSDVSMSSSPVVIDDVVMVQLECQGDSFVAGLDKKSGETLWHLDRPRVANFASPLAVPLPSGRQALFLSCSQSATIVDPASGEVIWETELDCKTTPSASVAGSTLVIPTAGLIAFDLTSDAPKPLWESDRLKARSASPVISGNRIYLAQGSVLVAGDLASGDEVWKQRIKGIGSQWATPVATQTGLFVFDDKGNCAVVKDNGDEAEVLAVSKIDGPMLASPAVSGDAIFARTENALWKIATK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP52</accession>
    <name>A0A518IP52_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Cysteine--tRNA ligase</fullName>
            <ecNumber evidence="11">6.1.1.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Cysteinyl-tRNA synthetase</fullName>
            <shortName evidence="11">CysRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11 14" type="primary">cysS</name>
        <name evidence="14" type="ORF">Mal33_08250</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>ATP + L-cysteine + tRNA(Cys) = AMP + diphosphate + L-cysteinyl-tRNA(Cys)</text>
            <dbReference type="Rhea" id="RHEA:17773"/>
            <dbReference type="Rhea" id="RHEA-COMP:9661"/>
            <dbReference type="Rhea" id="RHEA-COMP:9679"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78517"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="11">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 11">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.16" evidence="11"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004817">
        <property type="term" value="F:cysteine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006423">
        <property type="term" value="P:cysteinyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00672">
        <property type="entry name" value="CysRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00041">
        <property type="entry name" value="Cys_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015803">
        <property type="entry name" value="Cys-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015273">
        <property type="entry name" value="Cys-tRNA-synt_Ia_DALR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024909">
        <property type="entry name" value="Cys-tRNA/MSH_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032678">
        <property type="entry name" value="tRNA-synt_1_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10890">
        <property type="entry name" value="PTHR10890"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09190">
        <property type="entry name" value="DALR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01406">
        <property type="entry name" value="tRNA-synt_1e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00983">
        <property type="entry name" value="TRNASYNTHCYS"/>
    </dbReference>
    <dbReference type="SMART" id="SM00840">
        <property type="entry name" value="DALR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00435">
        <property type="entry name" value="cysS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="8 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 11 14" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 11" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="DALR_2" evidence="13">
        <location>
            <begin position="392"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="265"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="11">
        <location>
            <begin position="32"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="268"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="209"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="234"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="238"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="QDV54860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="542" mass="59628" checksum="36205019AA2B5042" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPE5</accession>
    <name>A0A518IPE5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Flagellar motor switch protein FliM</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">fliM</name>
        <name evidence="12" type="ORF">Mal33_09310</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Bacterial flagellum basal body</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the FliM family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009425">
        <property type="term" value="C:bacterial-type flagellum basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003774">
        <property type="term" value="F:cytoskeletal motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17908">
        <property type="entry name" value="FliM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028976">
        <property type="entry name" value="CheC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001689">
        <property type="entry name" value="Flag_FliM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001543">
        <property type="entry name" value="FliN-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036429">
        <property type="entry name" value="SpoA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02154">
        <property type="entry name" value="FliM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01052">
        <property type="entry name" value="FliMN_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002888">
        <property type="entry name" value="FliM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00955">
        <property type="entry name" value="FLGMOTORFLIM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101801">
        <property type="entry name" value="SSF101801"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103039">
        <property type="entry name" value="SSF103039"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01397">
        <property type="entry name" value="fliM_switch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="12" id="KW-0966">Cell projection</keyword>
    <keyword evidence="6" id="KW-0145">Chemotaxis</keyword>
    <keyword evidence="12" id="KW-0969">Cilium</keyword>
    <keyword evidence="7" id="KW-0283">Flagellar rotation</keyword>
    <keyword evidence="12" id="KW-0282">Flagellum</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FliMN_C" evidence="11">
        <location>
            <begin position="274"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="27"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QDV54963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="358" mass="39374" checksum="A1DBC44B9C758A50" modified="2019-10-16" version="1">MSDEILSQNQVEDLIRAMESEGASQPAPKPAASSTANAIPRSAASASRVNDPRLRPMNYDFKRPERVGKELMGAMRSLHEGLGRAFNAKLSGLLRSITEVKLVSADQLTYSEFVYSLDTPTCFCVLDVKPLEGNWILDIAPALSFAVVDRMLGGDPQPNEMPNRALTEIEHRLMARVTQLFLDGMQSTWQNVVEMEPTLRSIESNPQLVQIVPPNEVIVLICFEVTMGKNRGMMNLCIPYNTIERFSSQLSSKGWGGYSSNPATPESKQALETQLDSALVELTVTLARSKIKTGDLLNMDVGDVITTEHLIDKPLEVAIQSVPKFKATIGALKGKKAVRIRDHIDMRPKPPATEAAKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPI8</accession>
    <name>A0A518IPI8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">CTP synthase</fullName>
            <ecNumber evidence="9">6.3.4.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Cytidine 5'-triphosphate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Cytidine triphosphate synthetase</fullName>
            <shortName evidence="9">CTP synthetase</shortName>
            <shortName evidence="9">CTPS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">UTP--ammonia ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9 12" type="primary">pyrG</name>
        <name evidence="12" type="ORF">Mal33_09830</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>ATP + H2O + L-glutamine + UTP = ADP + CTP + 2 H(+) + L-glutamate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:26426"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + NH4(+) + UTP = ADP + CTP + 2 H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:16597"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>H2O + L-glutamine = L-glutamate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:15889"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </reaction>
    </comment>
    <comment type="activity regulation">
        <text evidence="9">Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Pyrimidine metabolism; CTP biosynthesis via de novo pathway; CTP from UDP: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homotetramer.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="9">CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the CTP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.2" evidence="9"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00159">
        <property type="reaction ID" value="UER00277"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003883">
        <property type="term" value="F:CTP synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044210">
        <property type="term" value="P:'de novo' CTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03113">
        <property type="entry name" value="CTPS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01746">
        <property type="entry name" value="GATase1_CTP_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01227">
        <property type="entry name" value="PyrG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004468">
        <property type="entry name" value="CTP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017456">
        <property type="entry name" value="CTP_synthase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033828">
        <property type="entry name" value="GATase1_CTP_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11550">
        <property type="entry name" value="PTHR11550"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06418">
        <property type="entry name" value="CTP_synth_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00337">
        <property type="entry name" value="PyrG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="4 9 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 9" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CTP_synth_N" evidence="11">
        <location>
            <begin position="3"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="GATase" evidence="10">
        <location>
            <begin position="304"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="region of interest" description="Amidoligase domain" evidence="9">
        <location>
            <begin position="1"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="L-glutamine binding" evidence="9">
        <location>
            <begin position="383"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile; for glutamine hydrolysis" evidence="9">
        <location>
            <position position="382"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="508"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="510"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="13"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="14"/>
            <end position="19"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="71"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="148"/>
            <end position="150"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <note>allosteric inhibitor</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="188"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="224"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="355"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="406"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="463"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF06418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QDV55015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="553" mass="61705" checksum="8BF9B4F48946CFFC" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPJ6</accession>
    <name>A0A518IPJ6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Tetracycline resistance protein, class C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">tetA</name>
        <name evidence="8" type="ORF">Mal33_09810</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. TCR/Tet family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001958">
        <property type="entry name" value="Tet-R_TetA/multi-R_MdtG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01035">
        <property type="entry name" value="TCRTETA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="82"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="106"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="140"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="170"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="217"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="257"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="287"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="309"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="348"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="378"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="7">
        <location>
            <begin position="11"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV55013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="419" mass="44674" checksum="95923BECF39DA621" modified="2019-10-16" version="1">MNKPGQRRQAAISFILITLFIDILGIGIIIPVLPELVKSFVEGSTANASWYVGVIGSVYALMQFIFAPIVGALSDRFGRRPVILCSLFGLGVDFIVQGLATNIGWLFAGRIFAGVMGASISTANAYIADVSTADTRARNFGLVGVAFGMGFIIGPALGGLLGAFDLRLPFFVAAGLALVNWLYGYFILPESLPPERRSSFTLAKANPLGSLQRLRQYPIVAGLAVAIVCTSLAQRGLENVWVLYTGYRFDWNQQTNGLALGLVGLMAMLVQGGLVRPTIKRFGERRTVLIGVTISFIAFLGYGSATQGWMIPCIIIFGGFGGVSGPAMQSLVAGAIDPSEQGKVQGALTSLISLTNVIAPTFFTAGLFSYFISDDAPIHLPGIPFYVGAALIFTALLIIRRVFRRIPETEQVEAGSLAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPN2</accession>
    <name>A0A518IPN2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_09880</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="295" mass="32144" checksum="75358F47EA1DFC34" modified="2019-10-16" version="1">MNLRILRIINRQSPRSRRLPVFSCARRCDRFASLRSLGLAFLTLLVGFAGPALSDETDRWGDLTIRFVYDGVPPQPQRIADRVGEGFCGDPTMIDESLVVNTIDKGIRDLVVYAYEGPGGRALPAVHPDAVSGGKAFELSNVNCNYVPRVLAITSGDALSVVNTDVIGYSTMLGFMANRAESLSLPPNARAELSPQRAEPAPIPVGSLLYPWMKARLLVLDHRYAGISDVHGRMTIGRLPAGVKLAFRVYHERASLRGLTIGGSEVNRRGVFELEIQPGENDLGTVSISAERFGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPV5</accession>
    <name>A0A518IPV5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Quinohemoprotein alcohol dehydrogenase ADH IIB</fullName>
            <ecNumber evidence="3">1.1.9.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">qbdA</name>
        <name evidence="3" type="ORF">Mal33_10820</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.9.1" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002372">
        <property type="entry name" value="PQQ_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13360">
        <property type="entry name" value="PQQ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="29"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="62"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="96"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="579" mass="62573" checksum="24D134B75F1E18FF" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQQ4</accession>
    <name>A0A518IQQ4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glucose--fructose oxidoreductase</fullName>
            <ecNumber evidence="3">1.1.99.28</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">gfo_4</name>
        <name evidence="3" type="ORF">Mal33_14000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.99.28" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047061">
        <property type="term" value="F:glucose-fructose oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004104">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02894">
        <property type="entry name" value="GFO_IDH_MocA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GFO_IDH_MocA" evidence="1">
        <location>
            <begin position="4"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="GFO_IDH_MocA_C" evidence="2">
        <location>
            <begin position="133"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="349" mass="37126" checksum="D354578945C1373F" modified="2019-10-16" version="1">MSIGFGIIGCGMIANFHAKALADAPGVELVACCARDLEKAKAFGEPLGIACYGSVEEMLADPKVAAVSIATPSGAHMEPALLAAEAGKHVVVEKPLEVTLERCDKIIDACDKAGVKLGVTLQSRFHKSSQLIKEAVEGDRFGTVTMGDAYVKWFRTQEYYDSGAWRGTWELDGGGALMNQAIHTVDLLTWMMGPVTEVTACTGTLAHERIEVEDVAVATVRFESGALGVIEASTAAFPGSLKRIEISGTLGTAVLEEEDIKTWEFAEMTDEDRRVQEEMIGKNKTGGGAADPAAIGHHGHTAVFTDVARAIQSGETPLVDGREGRRSVEIILAIYKAAKTKQSVPLPLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IR16</accession>
    <name>A0A518IR16_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphocholine transferase AnkX</fullName>
            <ecNumber evidence="3">2.7.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ankX</name>
        <name evidence="3" type="ORF">Mal33_14690</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.1.-" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="SSF48403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="89"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="122"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="156"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="21"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="211" mass="22021" checksum="82592F0B599EE4E0" modified="2019-10-16" version="1">MNPKYLHLSWPLLLALTGCGGAPDTPPPPAAPAAESADGDSDSETAEAPPQRITPITLADFRNAAAEGRIEPIRQGIEQGITVTAADEAGRTALMLAAFDGHTAVVELLLENKSEVNAKDSSARTALMYAASGPNDATVKRLLEAGAEVNLADNVEGFTALMFAAAEGQTEICKMLLAQKANREAKDVDGDTALSFAQKNNHAAVVQLLTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IR69</accession>
    <name>A0A518IR69_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PTS system mannose-specific EIIBCA component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">manP</name>
        <name evidence="2" type="ORF">Mal33_15200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd00211">
        <property type="entry name" value="PTS_IIA_fru"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016152">
        <property type="entry name" value="PTrfase/Anion_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002178">
        <property type="entry name" value="PTS_EIIA_type-2_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00359">
        <property type="entry name" value="PTS_EIIA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55804">
        <property type="entry name" value="SSF55804"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51094">
        <property type="entry name" value="PTS_EIIA_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PTS EIIA type-2" evidence="1">
        <location>
            <begin position="5"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="158" mass="17345" checksum="6853CF7A0A0B619B" modified="2019-10-16" version="1">MKFADFICVKAIKPDLASYDKEAVVTELVESLVTAGEIKTADKDDIIAAVMKREELGSTGIGRGVAVPHTKHPSVEKLVGTVGVSVDGVDFNSLDGEKVQLFFLLISPPERPGDHLRALENISRQLRDDTFCRFLKQSKTVDDINQLLEEADNNQFAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRA7</accession>
    <name>A0A518IRA7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">D-inositol 3-phosphate glycosyltransferase</fullName>
            <ecNumber evidence="3">2.4.1.250</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">mshA_4</name>
        <name evidence="3" type="ORF">Mal33_15980</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.4.1.250" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102710">
        <property type="term" value="F:D-inositol-3-phosphate glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="91"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="198"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="404" mass="45367" checksum="36BD2C247852A864" modified="2019-10-16" version="1">MSTNSAMHLGVVASVKHGFEHFVHRELSFFESRGAKISVYPTKFQAGLYGPRPTWNVYRWGLISLMFANLGTLLSRPASYLRLLAEAIRHRAVVDFVLAVYFAGKMRDVDLIYATFGDRKLFIAYFCKQLLNKPLICTIHAYEIYENPNPVMFARAVAACDQITTVTNYNREQLKSRYGIDPRRIEVVRLSIDLQTYRPERKFVVLIVGYFAQKKGHRILLEALRKIDNSEFELWVVGTGRDSADSVDVKALAAEMGLESQVAFFNGLSGTALRAVYHACDVFCLPSHHDDHGGAEGFPTVIIEAMACGKPVISTRHVEIPAIVEQILVDEKDVDGLADALLQTYRSADLREQMGERNRELAAEHFSHSNVKRTEAMMRAACGLPPLVEPEASPVEMQHESLTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRF9</accession>
    <name>A0A518IRF9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DNA polymerase III PolC-type</fullName>
            <ecNumber evidence="3">2.7.7.7</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">polC</name>
        <name evidence="3" type="ORF">Mal33_16500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.7.7" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Exonuclease_RNaseT/DNA_pol3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00533">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00929">
        <property type="entry name" value="RNase_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00292">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00479">
        <property type="entry name" value="EXOIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="SSF52113"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Exonuclease" evidence="2">
        <location>
            <begin position="7"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="domain" description="BRCT" evidence="1">
        <location>
            <begin position="299"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="386" mass="42430" checksum="24CB41C2E28B603F" modified="2019-10-16" version="1">MENNCDGYAVVDVETTGLGKHDRVIEIGIVLLDTRYRVVDEYESLIDPQRDLGPTHIHGITPSMVSLAPSFDEVAVAIARRIENRVLVAHNLMFDRRMLSQEFQRLGANFDPGLGVCTYKLTRQKLPLACKTLGLPPLVHHRALADARASAGIVKTLAPSQHRTPASVCNVPGNLTQRTHRRCADGTTPVLNRWLSRITIDVGDPRMVQYMDLLDWVLDDLVLSQDEQNYLNYLASELGLSNDDVALAHEHYFNSLIAAAEKDNIITVQEHTTLTAVADALGMSIDRVPKISSSDNENVEIPHGSTICFTGSFVDADGSPLSKATLESMAVQCGFNVVPNVTKSKCDYVVAVDPNSSSRKTKMARDFGKPVVGVQRFLDTLKQVNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRG1</accession>
    <name>A0A518IRG1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Succinylglutamate desuccinylase / Aspartoacylase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_16640</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016811">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007036">
        <property type="entry name" value="Aste_AspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043795">
        <property type="entry name" value="N-alpha-Ac-DABA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04952">
        <property type="entry name" value="AstE_AspA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039012">
        <property type="entry name" value="ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV55685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="340" mass="36860" checksum="B607D3A688B143EC" modified="2019-10-16" version="1">MSNELQKLDIGRWGDQVIGLGEDADVHLTISESYSSSMIQVPIHVRRAKAEGPVVFVTAAIHGDELNGTGAIRELIQEELELTRGALILVPVLNLLAFDRHTRYTPDRRDLNRSFPGSASGNMASRMARTLFDQIVGRADFGIDLHTAAIRRTNYPNVRGDLSNPAVRRIATAFGSEIVLNGQGPGGALRREACQVGCPTIIMEGGEIWKVEPDVVANAARGVRNVLRDLEMLGGPPEQAPYQVIVETSKWVRAEKGGFLQFHVQPGEVIVKGQPVATNTNLLGRERCILEAPFDAVVIGMTTLPAGSPGEPVCHLGMLPEGFDPETLHQLRGGTQREAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRG5</accession>
    <name>A0A518IRG5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FHA domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_16110</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd00060">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SSF49879"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="2">
        <location>
            <begin position="29"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="151" mass="17219" checksum="B1E6788A078A384C" modified="2019-10-16" version="1">MDDIGKVKRYGMLEPSSGGDPVPLLKERLTVGRRDSCDICLKFANISGQHCRLTLENGYWFARDMDSRNGTKVNGSRILRKRLDPGSVISFAKHEYTIEYNPQDLGAFGPPPPDEDQLSDVLRRSLMDRAGMNRRSESNRFKNEQHDDLDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRH8</accession>
    <name>A0A518IRH8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Serine/threonine-protein kinase PknE</fullName>
            <ecNumber evidence="4">2.7.11.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">pknE</name>
        <name evidence="4" type="ORF">Mal33_16690</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.11.1" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.100.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010496">
        <property type="entry name" value="3-keto-disaccharide_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001304">
        <property type="entry name" value="C-type_lectin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016186">
        <property type="entry name" value="C-type_lectin-like/link_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06439">
        <property type="entry name" value="DUF1080"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00059">
        <property type="entry name" value="Lectin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00034">
        <property type="entry name" value="CLECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="SSF56436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50041">
        <property type="entry name" value="C_TYPE_LECTIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="114"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="domain" description="C-type lectin" evidence="3">
        <location>
            <begin position="734"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="387"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="428"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="559"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="862"/>
            <end position="891"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="579"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="867"/>
            <end position="891"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV55690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1082" mass="117360" checksum="546E2A8C1085C3FF" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRU8</accession>
    <name>A0A518IRU8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_17940</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="223" mass="25242" checksum="ED73803D47CDD563" modified="2019-10-16" version="1">MNLPPEFSLTIQNHDDGWLPIEVVPYAESHAPWFSGVWKRMADGLAKSHALVNSPPPGWIQWKPWSWVHETKPGYERRNTLVALANSQVVGFINVWPDSPSGIDPSRNTLYIEHVAACPWNLTSQLWQRKYRHIGPALLAYAQWHSQSCGNDGNLSLHAADAAALDFYRKLESGRPQPLFTHKQTGILGPTPHGHHVDRKLTYLEIIANGGLELLEDYRNDKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRV3</accession>
    <name>A0A518IRV3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Sulfate adenylyltransferase subunit 2</fullName>
            <ecNumber evidence="2">2.7.7.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">ATP-sulfurylase small subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Sulfate adenylate transferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">cysD</name>
        <name evidence="8" type="ORF">Mal33_18080</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PAPS reductase family. CysD subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.4" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004781">
        <property type="term" value="F:sulfate adenylyltransferase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019419">
        <property type="term" value="P:sulfate reduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01713">
        <property type="entry name" value="PAPS_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002500">
        <property type="entry name" value="PAPS_reduct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011784">
        <property type="entry name" value="SO4_adenylTrfase_ssu"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01507">
        <property type="entry name" value="PAPS_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002936">
        <property type="entry name" value="CysDAde_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02039">
        <property type="entry name" value="CysD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PAPS_reduct" evidence="7">
        <location>
            <begin position="29"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="284"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00030256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00031812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV55829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="303" mass="35401" checksum="70FB53031962E375" modified="2019-10-16" version="1">MTDYNLTHLKQLEAESIHIIREVVSEFQNPVMLYSIGKDSAVMVQLALKAFYPAKPPFPLMHVDTTWKFREMIEFRDTYVRDELGLELIVHINEEGRELGIHPLDDSEKHTEVMKTDGLKQALDKHGFDAAFGGARRDEEKSRAKERVFSFRDRRHRWDPKNQRPELWNLYNTKVNKGESIRVFPLSNWTELDVWQYIHLENIPIVPLYKSAVRQVVERDGVLIMLDDERVQLRPGEKPMEKMVRFRTLGCYPLTGAVESEATTLPEIIQEMLLTRTSERQGRLIDKDEGGAGMQKKKERGYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRY5</accession>
    <name>A0A518IRY5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative monovalent cation/H+ antiporter subunit E</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Mal33_18360</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002758">
        <property type="entry name" value="Cation_antiport_E"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34584">
        <property type="entry name" value="PTHR34584"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01899">
        <property type="entry name" value="MNHE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="34"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="58"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV55857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="191" mass="21201" checksum="230BC3116F3E57DA" modified="2019-10-16" version="1">MKWLTAPLQVDLIDRYSASILPIVRECVEHTVKYLFIITLSIALFATWLLWSGHFDDPFLIALGVGACVISVALSRRMKIVDEEGAPAHLGLRPFTSYAPWLIKEIVQSNMEVTRIILSPKMPLQRSMIRVSANQQTELGRVILANSITLTPGTVTVRVEGNSILVHALSFEGAAEDLSGEMDRRVCALEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IS48</accession>
    <name>A0A518IS48_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">tRNA modification GTPase MnmE</fullName>
            <ecNumber evidence="2">3.6.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">mnmE_1</name>
        <name evidence="2" type="ORF">Mal33_19050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.6.-.-" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04164">
        <property type="entry name" value="trmE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.430">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031168">
        <property type="entry name" value="G_TrmE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018948">
        <property type="entry name" value="GTP-bd_TrmE_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027368">
        <property type="entry name" value="MnmE_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027266">
        <property type="entry name" value="TrmE/GcvT_dom1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10396">
        <property type="entry name" value="TrmE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51709">
        <property type="entry name" value="G_TRME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TrmE-type G" evidence="1">
        <location>
            <begin position="189"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="385" mass="40264" checksum="48213FD90348EA26" modified="2019-10-16" version="1">MNASGNDAALQTCVLTPIGRGAIATVAVRGATAAEIVGKYFCPNAGSSHLPIDRIRYGVWSRDADSAIGESIVVCATAETEIEIHCHGGRAAVEAIVGDLVASGAERIGGDSWLQGRSDNFLSSECQLALAATQTPTTAGIVLDQIRGALATATQAAIEQLRSANLEAAGQAIQTLIDRAPLGRGASKPFRVVIAGPPNVGKSSLLNRLLGYDRAIAYDQPGTTRDVLSARTTLGGWTIELRDTAGIHETAEAIEREGVQSARREVQSADAVLIVVDASVGWTPEHDEIAKLVPNPIRVWNKADLIDVEAMPDAAEKIFTSTLSQAGIDDLIAAILQQLIPQPHAAGMAVPITDRQLACLQEAQAAIASSDATSAAVHLQRLLRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IS82</accession>
    <name>A0A518IS82_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ferritin-like domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_19210</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008199">
        <property type="term" value="F:ferric iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009040">
        <property type="entry name" value="Ferritin-like_diiron"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008331">
        <property type="entry name" value="Ferritin_DPS_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00210">
        <property type="entry name" value="Ferritin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50905">
        <property type="entry name" value="FERRITIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ferritin-like diiron" evidence="1">
        <location>
            <begin position="1"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="152" mass="16839" checksum="642C3A68F82C59B1" modified="2019-10-16" version="1">MASQELIAHLNEILKHEWTGVAQYSQAAFIIEGVWREVYAERFLGDAKESFGHAQLIGDKIVALGGVPVATRNEIQQSRDLQEVLQFSLEFESKAVDMYEKALDMAEGNRPLVIFLEDILNDEQEGVDEYTKLLRNSTAAGAAATHSAKKSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISC5</accession>
    <name>A0A518ISC5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Na(+)-translocating NADH-quinone reductase subunit B</fullName>
            <shortName evidence="13">Na(+)-NQR subunit B</shortName>
            <shortName evidence="13">Na(+)-translocating NQR subunit B</shortName>
            <ecNumber evidence="13">7.2.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">NQR complex subunit B</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">NQR-1 subunit B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13 15" type="primary">nqrB</name>
        <name evidence="15" type="ORF">Mal33_19680</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>a ubiquinone + H(+) + n Na(+)(in) + NADH = a ubiquinol + n Na(+)(out) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:47748"/>
            <dbReference type="Rhea" id="RHEA-COMP:9565"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="7.2.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13 14">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="13">Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Cell membrane</location>
            <topology evidence="13">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the NqrB/RnfD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="7.2.1.1" evidence="13"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016655">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022904">
        <property type="term" value="P:respiratory electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006814">
        <property type="term" value="P:sodium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00426">
        <property type="entry name" value="NqrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010966">
        <property type="entry name" value="NqrB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004338">
        <property type="entry name" value="NqrB/RnfD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30578">
        <property type="entry name" value="PTHR30578"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03116">
        <property type="entry name" value="NQR2_RnfD_RnfE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016055">
        <property type="entry name" value="NADH-UbQ_OxRdtase_B_su"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01937">
        <property type="entry name" value="nqrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="2 13" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 13 14" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6 13 14" id="KW-0288">FMN</keyword>
    <keyword evidence="11 13" id="KW-0406">Ion transport</keyword>
    <keyword evidence="12 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="10 13" id="KW-0520">NAD</keyword>
    <keyword evidence="15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 13 14" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0915">Sodium</keyword>
    <keyword evidence="13" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="8 13" id="KW-1278">Translocase</keyword>
    <keyword evidence="7 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1 13" id="KW-0813">Transport</keyword>
    <keyword evidence="13" id="KW-0830">Ubiquinone</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="58"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="140"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="177"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="312"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="365"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="394"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="418"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="modified residue" description="FMN phosphoryl threonine" evidence="13 14">
        <location>
            <position position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR016055-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="QDV55989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="452" mass="48561" checksum="25A41DE2D5B8C4ED" modified="2019-10-16" version="1" precursor="true">MKALREFLDQKVEPWFKKGSPLAMLHPMYEAPDTFLYTPGHVAKGSTHVRDNIDLKRMMIMVVVALIPCTLFAMWNTGYQANLAMAKMESAGYEILTPAEYELVPKTEIPLRKLAKTDWHYTIQTAIGLGRDPGSFVDNFVFGALHFLPIYIVCMFVGGHIEALFCVVRGHEINEGFLVTGLLFPLTLPPTIPLWQVAIGIAFGVIVGKEVFGGTGRNFLNPALTARAFLYFAYAGEISGDKVWTAVDGFSGATSLGAMASAVPGAGMAPVTGEFDAAGDLVAGGIATSWGTQTLTWWDCFLGTIQGSMGETSALACLIGAAILIAAGIGSWRIMAGTVVGAVATAALMNAIGSDKYAMFEMPPMWHLVVGGFAFGAVFMATDPVSAAMTNTGRWIYGVLIGFMTILVRVVNPAYPEGIMLAILFANVFAPLIDYYVAQANIKRRVARYATS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISD3</accession>
    <name>A0A518ISD3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Methylated-DNA--protein-cysteine methyltransferase</fullName>
            <ecNumber evidence="8">2.1.1.63</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ogt</name>
        <name evidence="8" type="ORF">Mal33_19860</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 4-O-methyl-thymidine in DNA + L-cysteinyl-[protein] = a thymidine in DNA + S-methyl-L-cysteinyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:53428"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:10132"/>
            <dbReference type="Rhea" id="RHEA-COMP:13555"/>
            <dbReference type="Rhea" id="RHEA-COMP:13556"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:82612"/>
            <dbReference type="ChEBI" id="CHEBI:137386"/>
            <dbReference type="ChEBI" id="CHEBI:137387"/>
            <dbReference type="EC" id="2.1.1.63"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a 6-O-methyl-2'-deoxyguanosine in DNA + L-cysteinyl-[protein] = a 2'-deoxyguanosine in DNA + S-methyl-L-cysteinyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:24000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:10132"/>
            <dbReference type="Rhea" id="RHEA-COMP:11367"/>
            <dbReference type="Rhea" id="RHEA-COMP:11368"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:82612"/>
            <dbReference type="ChEBI" id="CHEBI:85445"/>
            <dbReference type="ChEBI" id="CHEBI:85448"/>
            <dbReference type="EC" id="2.1.1.63"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.1.1.63" evidence="8"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003908">
        <property type="term" value="F:methylated-DNA-[protein]-cysteine S-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06445">
        <property type="entry name" value="ATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001497">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014048">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036217">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_DNAb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01035">
        <property type="entry name" value="DNA_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46767">
        <property type="entry name" value="SSF46767"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00589">
        <property type="entry name" value="ogt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00374">
        <property type="entry name" value="MGMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DNA_binding_1" evidence="7">
        <location>
            <begin position="177"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV56007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="267" mass="29099" checksum="AF1F3E9E1F1E2B27" modified="2019-10-16" version="1">MVRPSPTALASEPHLAAPRGTIRRRPPGFGIALANSESARSRQQHGGQPAGRRGILLRTLISRSSRLKNEACDSNSLLFVPEPAIAHSLKSEMPAIQCTGLCETPLGLLVHRWTGAGLYQVELCADPASPKIKAALEGPDSAATPEIEAFTNRIDQYFAGQLTTFDEIPIDESDWPPFFGQVYRACRQVESGQTISYQELARRAGRPAAARAVGQAMARNRIPIVIPCHRIVGSSGRMTGFSADGGIETKRWLLDRERSDSLFDIDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISH6</accession>
    <name>A0A518ISH6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Arylsulfatase</fullName>
            <ecNumber evidence="5">3.1.6.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">atsA_15</name>
        <name evidence="5" type="ORF">Mal33_20230</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="PTM">
        <text evidence="1">The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.</text>
    </comment>
    <dbReference type="EC" id="3.1.6.1" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004065">
        <property type="term" value="F:arylsulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021946551" evidence="3">
        <location>
            <begin position="24"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase" evidence="4">
        <location>
            <begin position="28"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="493"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="modified residue" description="3-oxoalanine (Cys)" evidence="1">
        <location>
            <position position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR600917-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV56044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="512" mass="57604" checksum="848B0FBECE1978C9" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISP6</accession>
    <name>A0A518ISP6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_20960</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="99" mass="10739" checksum="B413CEB99694E6F5" modified="2019-10-16" version="1">MGRVGSFLLGVAVGAGTLYTAMNYHVVRSEGGTHLVRKTEVGLVGTYADIRQYSISDWRQRPQLTQAMLKAQRSDLMAASPTQNLQQRVGSIVGGVFGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IST3</accession>
    <name>A0A518IST3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_21330</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="80" mass="9152" checksum="42D059FADF6679FD" modified="2019-10-16" version="1">MNNSITILIDDKHVPLYRIMWVADTPHFCGEEDCTREGQYEVRLELDESVWASRAERDSVLESINGSRDGVDPGEEDGPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISU2</accession>
    <name>A0A518ISU2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Magnesium-protoporphyrin O-methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.11</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">bchM</name>
        <name evidence="1" type="ORF">Mal33_21410</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.1.1.11" evidence="1"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046406">
        <property type="term" value="F:magnesium protoporphyrin IX methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="248" mass="27527" checksum="0C2CE72D31BED302" modified="2019-10-16" version="1">MPTDCQTDTLYGDDVAYIHDVGYSGLCESWEKGLLEIFRAAGIDDGKVVDLGCGGGRWTQRLAAAGYTPVGVDISAAMIDLATKRLPSAEFHVASVWNYQFPCCRAVTALSEVLCYRSPTCDDPDLSDLFNRVFTALQPGGLFLFDVTEIGLDQDGQRTFSEGDDWACLVRYENDDVTQRLLRHITSFRKVGDSYRRHSETHTAQLFDADQLAALLRQAGFEVRTTRKFGAAELLPQRCGLIARKPQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IT17</accession>
    <name>A0A518IT17_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_21840</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005229">
        <property type="entry name" value="CHP00255"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013551">
        <property type="entry name" value="DUF1732"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013527">
        <property type="entry name" value="YicC-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30636">
        <property type="entry name" value="PTHR30636"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08340">
        <property type="entry name" value="DUF1732"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03755">
        <property type="entry name" value="YicC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00255">
        <property type="entry name" value="TIGR00255"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YicC_N" evidence="1">
        <location>
            <begin position="2"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1732" evidence="2">
        <location>
            <begin position="210"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="294" mass="32723" checksum="ECE17B7D51842FDD" modified="2019-10-16" version="1">MLQSMTGQGQAQSTGDLGTVSVEIRTVNNRGLKLSARLGDQLNRLEPQVDAVVRQHLTRGSVNLNARWQRASAASAYRINEAALTEYHRSLSQLQTKLDDTAPIDLAQLAALPGVIQEADDQTIDPKELWALLQPVLVAALENLNQMRAAEGASMLTSLQTDLALIAEHLEAICKLAPRVVDGYRERLESRIGDLLRERGLEVATIDLLKELQVFADRTDISEEITRLQSHLQMFDETVASEQASGRRLDFVIQEMFRETNTIGSKANDAEIAMHVVDMKCAIERMRELIQNIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IT58</accession>
    <name>A0A518IT58_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_22660</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="116" mass="13705" checksum="306F9D9FDA435B39" modified="2019-10-16" version="1">MKKTDADQAEQSYFRHNFRFWLEKRPKGTLGQLRNWLKRVHNQCLDFVGSGDPPIEGTDDIPNELSEYLKYWGEHDDESFSYREANIEEDIINLEGFIEDLDPKTKLASFPLYKFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITC9</accession>
    <name>A0A518ITC9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glyoxylate/hydroxypyruvate reductase B</fullName>
            <ecNumber evidence="6">1.1.1.79</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ghrB_1</name>
        <name evidence="6" type="ORF">Mal33_23270</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.79" evidence="6"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030267">
        <property type="term" value="F:glyoxylate reductase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006139">
        <property type="entry name" value="D-isomer_2_OHA_DH_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029753">
        <property type="entry name" value="D-isomer_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029752">
        <property type="entry name" value="D-isomer_DH_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00389">
        <property type="entry name" value="2-Hacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00065">
        <property type="entry name" value="D_2_HYDROXYACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00670">
        <property type="entry name" value="D_2_HYDROXYACID_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00671">
        <property type="entry name" value="D_2_HYDROXYACID_DH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2-Hacid_dh" evidence="4">
        <location>
            <begin position="18"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="domain" description="2-Hacid_dh_C" evidence="5">
        <location>
            <begin position="101"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV56345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="311" mass="33721" checksum="ED890CC135474117" modified="2019-10-16" version="1">MKDIILTDPLPKFFLPPAQVRCELRYFDSATDADFAAARGILAYGHVRIDAPMMDRCPQLRVISNHGVGVDHIDLQAAAARGIPVGNTPGCVDAATADLTIALMLATARRLVVSDAFARSAEFTQYNPAILIGQEVTGSTLGIVGMGRIGCEVARRAKAFQMRLLYHNRSRRPEAEAEFGAEYRSLDDLLQESDFVSLNCPLTAETTGLIGAAELGKMKPTGILLNLARGQVVVTQALYEALRDEKIQAAGLDVTDPEPLPRDHPLLQLSNVIITPHLGSATGRTRHTMMQRTLENLFAGLDGKPLPNEVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITI6</accession>
    <name>A0A518ITI6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_23870</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="117" mass="13131" checksum="CDBCA3D6737A2130" modified="2019-10-16" version="1">MSNTTTEVVDESRANDRRGEAKALIARGMDQAEACRLSGFRDRYGEQLKPDPNTGWIPTPDEILAEAARIRSEWPDGLEPHGVVLAGFRGNRDTRAARCSRVVPMRAFAVDRRFEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITR6</accession>
    <name>A0A518ITR6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_24720</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="99" mass="11414" checksum="794B171A2E96976C" modified="2019-10-16" version="1">MSHTTELSLKNLHLLSPDLATDFTEQLHAAVLDCRQRPSLAEKREVTIKLIVQPHPEDPDDVTIQPVTSRKTPARKIDVVRARRTTRNQLQFDFDEEML</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IU44</accession>
    <name>A0A518IU44_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">cAMP receptor protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">crp</name>
        <name evidence="4" type="ORF">Mal33_26080</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012318">
        <property type="entry name" value="HTH_CRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13545">
        <property type="entry name" value="HTH_Crp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00034">
        <property type="entry name" value="HTHCRP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00419">
        <property type="entry name" value="HTH_CRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="SSF51206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51063">
        <property type="entry name" value="HTH_CRP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0675">Receptor</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="2">
        <location>
            <begin position="13"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="HTH crp-type" evidence="3">
        <location>
            <begin position="147"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV56616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="236" mass="26663" checksum="E8D5CD4AAA45ED08" modified="2019-10-16" version="1">MPEKLWHLQNCDLFARLLPEQIERLETRCRSRSFRARSPVYLPSEKADSVFLLTKGLVKVCNHTPDGKQSILAFVEPGEMFGELALFADVAREEYVEAVEPTTVVMIPADALQQLMSQHGGVALAITKMVGLRRSRIERRLKNLLFVSNRDRLIHLLLDLAEQFGSVADDGIRLRISLAHQEIANLLGSTRETVTILLGQLRAEGFINVGRRKIVLTDPQRLSQSVQRKIPYQLLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUB7</accession>
    <name>A0A518IUB7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_26750</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="320"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="54"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="320"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="447"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="484"/>
            <end position="522"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="638" mass="67413" checksum="3BDA098803225B3E" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUV4</accession>
    <name>A0A518IUV4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DprA_WH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_28560</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DprA/Smf family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009294">
        <property type="term" value="P:DNA-mediated transformation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003488">
        <property type="entry name" value="DprA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041614">
        <property type="entry name" value="DprA_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43022">
        <property type="entry name" value="PTHR43022"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02481">
        <property type="entry name" value="DNA_processg_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17782">
        <property type="entry name" value="DprA_WH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="SSF47781"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00732">
        <property type="entry name" value="dprA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DprA_WH" evidence="2">
        <location>
            <begin position="303"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="359" mass="37963" checksum="744F834FA4371F64" modified="2019-10-16" version="1">MLPGIGPRTLTALLECFDSPSDVLAASADALMRVAGVGPKLVDAIRSPNAQVDVEDLIAECQRLEIEIVPQAADGYPKRLLELCDAPPVLFMRGTFVKEDELAVAIVGTRHPTPYGRRQTQLLSAGLARAGVTVVSGLARGIDGIAHQAALDAGGRTIAVLGGGMGAIYPAEHGGLADDVTANGCLISENPPWAKPRAGMFPQRNRLISGLSLGVCVIEAADRSGALITARLASEQGRDCFALPGPVNSRMSRGTNQLIRDGVTLIQSVDDILESLGPLSQPVQVRDADDAPRQLHQAAELLLNEQECQVLDAIGAMATSIDEIIANTKLPAHRVLSTVSVLEMRRLVRRTGGQHLVRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVB1</accession>
    <name>A0A518IVB1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glyco_hydro_32N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_30160</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 32 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013148">
        <property type="entry name" value="Glyco_hydro_32_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00251">
        <property type="entry name" value="Glyco_hydro_32N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="SSF75005"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021708779" description="Glyco_hydro_32N domain-containing protein" evidence="2">
        <location>
            <begin position="28"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_32N" evidence="3">
        <location>
            <begin position="362"/>
            <end position="545"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV57015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="592" mass="65234" checksum="2FC6BCF4AF6D2A3B" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVF1</accession>
    <name>A0A518IVF1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">EcoKI restriction-modification system protein HsdS</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Mal33_30670</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the type-I restriction system S methylase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="REBASE" id="355363">
        <property type="entry name" value="S.PbaMal33ORF30680P"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.220.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000055">
        <property type="entry name" value="Restrct_endonuc_typeI_TRD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044946">
        <property type="entry name" value="Restrct_endonuc_typeI_TRD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01420">
        <property type="entry name" value="Methylase_S"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0680">Restriction system</keyword>
    <feature type="domain" description="Methylase_S" evidence="5">
        <location>
            <begin position="22"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="Methylase_S" evidence="5">
        <location>
            <begin position="234"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="400"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV57066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="454" mass="50554" checksum="FBAA77377F5FAF36" modified="2019-10-16" version="1">MATYPEYPEYKLSDETWLGKIPVDWELIRIGHLSPVKRGASPRPIEAERYFDDEGEYAWTRISDVTASDMYLNHCPERLSDLGSSLSVKLQPGELFLSIAATVGKPCITAIKACIHDGFVYFPQLNIPNKFLFYVFTAGHAYAGLGKMGTQLNLNTETVSKIKIALGTPEEVKTIVQFLDYETAKIDALIEKQQQLIALLDEKRQAVISHAVTKGLNPDAPMRDSGIEWLGEVPEHWTVCRIKQIAKRETGHTPSKKVDTYWVDCEIPWVSLNDTGQLKHVDFISETAICINEKGMANSSAHLLPPGCVVFTRDASIGLAAITSREMAVSQHVIAWDCDPEIVNNEYLLLVFYAMEAELERFTFGATLKTIGMPDVNRLTGAFPPLQEQADIVKHVFSTKEKLSASIEKAEKLLDILEERRTALISAAVTGKIDVRGWKPPSTAAQQETEMEVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVR2</accession>
    <name>A0A518IVR2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_31820</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="23"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="123" mass="13845" checksum="CCF361E4D9E7C477" modified="2019-10-16" version="1">MTSRVGDLAEYFQTTANQSNHSMAVGVTVGILAPAVGVGYLLYRKYCGSEHEFYAPNKVFSGLCRAHRLDRRDRRLLLQIAAEMKLDQPALLFTNPALLRTASRKQIAAPAKRIKRLHRTLFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVS2</accession>
    <name>A0A518IVS2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_31800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="1 2">Mal33</strain>
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        <source>
            <dbReference type="EMBL" id="QDV57179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
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</entry>
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
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                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
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        <source>
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    </evidence>
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        <source>
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                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
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                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
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</entry>
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        <submittedName>
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                <person name="Ovreas L."/>
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            <strain evidence="1 2">Mal33</strain>
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    </reference>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="75" mass="8406" checksum="E5FC7BA4A464D26A" modified="2019-10-16" version="1">MTVRTLIDGLSREERREAFEVLWQALLGEDSLEVPAWHGEVLSQRLTNPSAGPSLPLDDAIEEVRRRLDGRPPSA</sequence>
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    <name>A0A518IWM0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_34860</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010496">
        <property type="entry name" value="3-keto-disaccharide_hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06439">
        <property type="entry name" value="DUF1080"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022055686" evidence="1">
        <location>
            <begin position="21"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1080" evidence="2">
        <location>
            <begin position="54"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1080" evidence="2">
        <location>
            <begin position="241"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="427" mass="47270" checksum="6F898301832D2284" modified="2019-10-16" version="1" precursor="true">MQRSAFIVPLLALVCTFANAQDTTSNFTSLVPESGLEGWHGRPHLDPRKYADVDAEKLAQWKQETEAHWSNKDGVLINDGHGPYLTTDKEYTDYELKLEYRTVAKADSGIYLRGTPQVQIWDTTDESKFKLGANLGSGALWNNSAGAPGKDPLVKADKPFGEWNSVRVIQVGQRTTVYLNDQLVVDNALMENYWDRSQPLFRSGPIQLQTHGGEILWRDVAIREIGADEANQILASHGNEGFESVFDGKSLKGWKGAVDNYEVVDGMIRCKPKHGGTLFTDKTYGDFKVRVMFRLPPGGNNGLAIRYPGEGNPAYSGTTELQVLDNTAEKYAKLDARQYHGSAYGMAAAARGFLRDVGQWNFQEVTVKGPTITVELNGNKILETDVSKVTEFMADTPHPGRELSKGHFGFAGHNDPVEFKEISILPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWM2</accession>
    <name>A0A518IWM2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_35000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="95" mass="10699" checksum="EC932BA83DACDB3E" modified="2019-10-16" version="1">MVRAFLKHCEEAVDDEELQEIHRDLYDFMLALGPALASRDDAAYLKQAKKKLSKLRKATELFVAIQPEVSGHTNFQMAARSLQTAVDQIVVLVRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWM8</accession>
    <name>A0A518IWM8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_35090</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022274">
        <property type="entry name" value="Peptidase_asp_AF0612"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03698">
        <property type="entry name" value="clan_AA_DTGF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="130" mass="13974" checksum="E5F3BF9BEB3159C2" modified="2019-10-16" version="1">MKGIVDNGGRALVPVELRRSTDTDATTFQVWIDTGFTGDLVLPTAAIEDLQLEPSGSVDAILADGSQIGLSTYSCTIEWFGTSRPLEIIANQGESPLLGVGLLLGLELRVDYRNLRVDLTPSQKDDVGVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWN1</accession>
    <name>A0A518IWN1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_35100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="83" mass="9302" checksum="0E26452CB190D533" modified="2019-10-16" version="1">MIQNTDPSVADRAKKIYEDRLKSVLEKRALDQFVAIEPDSGEYFLGATLSEAIGKARKKFPDRLSHAIRVGHKAAVHFGVHVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWN9</accession>
    <name>A0A518IWN9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_35070</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021980127" evidence="1">
        <location>
            <begin position="20"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="415" mass="45847" checksum="B5CBCA8AE0BDA790" modified="2019-10-16" version="1" precursor="true">MQSPSKPTRRAFLASTAIAATSSPWLNVATAETPAVKTKSVAAVLTAYEHGLHADVLIGKILEGWKQDGGPGPRLTLASMYVDQFTDRDMARGLSQKYGFPIFETIEEAVTVGGNTIPVDGVISIGEHGDYPWNDKQQHLYPRRRFFKEITDTFVKYDRVVPVFNDKHLGPVWKDAKWMYDRAVELNIPFMAGSSMAVGYRTPEISVPPGSPIEAAVGIGYSGLDIYGSHALEFFQCHVEQRPGAEQGVRWVQCLQGDAVWQTLDDGLISQDLFDAALAAIDHRDGDVRQSDDATLFLFQYTDGLLGAVFMLPTYARGTSVALQVAGKTKPLATRFDERREPRYPHFAWLLKGIETMFHTGQPTYPVERTLLTSGILDRALTSLAEGQTKRMTPELEIAYPPANYGHAPLPRLSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWQ3</accession>
    <name>A0A518IWQ3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Xylose isomerase-like TIM barrel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_35280</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="QDV57518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="Xyl_isomerase-like_sf"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF51658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AP_endonuc_2" evidence="1">
        <location>
            <begin position="21"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="302" mass="32524" checksum="F12A2D999A575BC6" modified="2019-10-16" version="1">MYKNFAAQGLGISGRQSELIELALTYGFRGLDIDLSDMYRRVQRSDFDRAARFLHAADIVVSGFDVPVDLDADDDAFAAQVAQLHPAAEVAGKLNAKVASVVVPAATDRLPYHEYFEAITKRLNQIAECLGGQEIQLAVGFQAASELSEGKQFEFIRNVEGFLPLVKGAGDNIGFLIDTFNWFAGAGTLEQLTALDAEKIFAVRLSGICEEAEADAIKRADRTLPEINEKIDFVGLATHLVASNYSGPVSAYSAPGNVRGGTRETVSNKAQEALDAIFTGAGLTVAPRPMDTISDIVVDMME</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXB4</accession>
    <name>A0A518IXB4_9BACT</name>
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        <submittedName>
            <fullName evidence="8">RDD family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Mal33_37420</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
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            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
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            <topology evidence="1">Multi-pass membrane protein</topology>
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        <property type="protein sequence ID" value="QDV57729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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            <end position="57"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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            <end position="84"/>
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            <end position="174"/>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
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            <begin position="309"/>
            <end position="330"/>
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    </feature>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
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            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
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        <source>
            <dbReference type="Pfam" id="PF06271"/>
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    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV57729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="330" mass="35926" checksum="A36FC357DB37B340" modified="2019-10-16" version="1">MFPTAPLDTTIEVVTPENIAFKYQLAGPFRRLPAFLIDLVVKAVLIMIAVLAVALFAGVTGSQLAGVVGFAAINVGWFLVWWFYGVAMETWFNGRTLGKMAMRIRVVTVSGHPIGGVQAMLRNLVCVADLAPPISLQFFAADAPPVYLIPTGIAGLVVMTCTRRMQRLGDLAAGTMVVIDERGWTLPVAQVEDARIPALASYIPPGYRVSPSLAKVLALYAERRLFLSPPRRRELAKNLAAGLSERFEFREDLDPDLLLYALYWRTYLADARDQDVDLQPLNGYSPLQKDAALVAVEAVPSEPSEFVTAVVAGDQPPPDSPTDPSSETKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXE1</accession>
    <name>A0A518IXE1_9BACT</name>
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        <submittedName>
            <fullName evidence="1">Thioesterase superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_37600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
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    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
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    </dbReference>
    <proteinExistence type="predicted"/>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="153" mass="16771" checksum="1A80CFDE1114D6E6" modified="2019-10-16" version="1">MSSTDFERPTALQDFPLVVRIPIQWGDLDAYGHVNNVVYMKWFEHVRCLYGERVGVEVVSRDSGTGAIVASVQCKYLRQLNFPGDVAVGVRVCRVSIGSVSLECLIVDEATGVPAAQATCDVVLYNFAQQKPVPVPDAIREAVEKLEGKSFPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXK2</accession>
    <name>A0A518IXK2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ComEC family competence protein</fullName>
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    <gene>
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    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetia</taxon>
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    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
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    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030420">
        <property type="term" value="P:establishment of competence for transformation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07731">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035681">
        <property type="entry name" value="ComA-like_MBL"/>
    </dbReference>
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        <property type="entry name" value="ComEC_N"/>
    </dbReference>
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        <property type="entry name" value="Competence_ComEC/Rec2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025405">
        <property type="entry name" value="DUF4131"/>
    </dbReference>
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        <property type="entry name" value="Metallo-B-lactamas"/>
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        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13567">
        <property type="entry name" value="DUF4131"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00360">
        <property type="entry name" value="ComEC_N-term"/>
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        <property type="entry name" value="ComEC_Rec2"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="27"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="359"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="433"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="464"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="528"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="552"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="domain" description="Lactamase_B" evidence="7">
        <location>
            <begin position="586"/>
            <end position="786"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV57819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="838" mass="91104" checksum="84A640B1FB6CEA33" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXP0</accession>
    <name>A0A518IXP0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulatory protein ZraR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_38630</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="13"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="155" mass="17168" checksum="432948DE22A1E5AA" modified="2019-10-16" version="1">MSHITHRHRSGATLLVVDPRPVSLTALAAVIDSQGYECYCARNAKAACKAVEQRPIDMIVWDVADDAAAAIDQIHALRELHPESLADVPVILIAESCWAGLETRLDPISPARCLFKPLDPNTLIDLIQQSLWVPHVIRGHHLNVQKPQRPGWVQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXQ1</accession>
    <name>A0A518IXQ1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_38780</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021943340" evidence="1">
        <location>
            <begin position="27"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="264" mass="28952" checksum="12C1C84D14C69CB8" modified="2019-10-16" version="1" precursor="true">MFAIKPMHRNAAMVLMFACLSGLLLAGPLAAQSSEHPTLRAETQIYSDGRKPSLVGETLTLFDAGVAYDVQLPAKSQITVFDIPRSKIVLIDTTTQRRTTINCDELVRYMTALRQQAQETGKAAAIGVSTQPIGDPQSGVFQAGFPGFLYTAETQPAAQPQLSQIYNEFTGWATRLNMYQNPRGAPFARLALNEQMSESNVLPSKITVRATVGDQTETLRSEHQFSPMLSVQDRALISQIGGMLVSFQDVPAEQFRTPRVAQNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXX8</accession>
    <name>A0A518IXX8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">ATP synthase subunit b</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">ATP synthase F(0) sector subunit b</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">ATPase subunit I</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">F-type ATPase subunit b</fullName>
            <shortName evidence="11">F-ATPase subunit b</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11 15" type="primary">atpF</name>
        <name evidence="15" type="ORF">Mal33_39540</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).</text>
    </comment>
    <comment type="function">
        <text evidence="10 11">F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cell membrane</location>
            <topology evidence="11">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11 12">Belongs to the ATPase B chain family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045263">
        <property type="term" value="C:proton-transporting ATP synthase complex, coupling factor F(o)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01398">
        <property type="entry name" value="ATP_synth_b_bprime"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002146">
        <property type="entry name" value="ATP_synth_b/b'su_bac/chlpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005864">
        <property type="entry name" value="ATP_synth_F0_bsu_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00430">
        <property type="entry name" value="ATP-synt_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01144">
        <property type="entry name" value="ATP_synt_b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 11" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="11" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 11 12" id="KW-0138">CF(0)</keyword>
    <keyword evidence="13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 11 12" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="7 11 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0732">Signal</keyword>
    <keyword evidence="4 11 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 11 12" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021753163" description="ATP synthase subunit b" evidence="14">
        <location>
            <begin position="29"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="65"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="109"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="QDV57938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="218" mass="23624" checksum="8789B2471546DFF9" modified="2019-10-16" version="1" precursor="true">MKLIRSSCLTALWLTLAMAIVAPAACQAADDHAAKAEAASDHETDGHEQGHAETPFLLKADPGAALWNLAIFAVVFLVLAKFIWPPILEGLQAREAKIHDDLTDAERARSTANAMLSEYQTKLDDAQTKVQSMLAEARRDAEQSKQGIIDEAKAEADRQHDRAVAEIQSAKTVAIGELASHSSAIALQLARQVVGRELNESDHADLIRKSLDNMPSKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXY9</accession>
    <name>A0A518IXY9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_39670</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021836543" evidence="1">
        <location>
            <begin position="49"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="316" mass="35550" checksum="C2145CFBE017EC54" modified="2019-10-16" version="1" precursor="true">MNEPNSRRVDGTKLLTSSATPKLRCGTRQEFRVLLICMLSLAVVPAQAVEPIEPTAVVAGIDADPLAGMPDAEAGRLRQIVADLIRSSIPETYQNEKDWGHQKRIYAGVKVRRDGWKIDTKRRWREVNHGAWTRYEIRLIDPDQHMKADLHDLRWLPDGTATFQLTLAGRLNCFARRSRWNYGVQLWSFNVDADADIEITIVGSIGVGLDYVNIPPDVVVKPVIESAQIAVPRFEVNRISDVGGDFAEGIGDALEGILRDEIISKQQVKLVERMNRQIARKEETLRFSMSDWLSKLLSDKTLAAEKTKADLMPGRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYA8</accession>
    <name>A0A518IYA8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">Xylulose kinase</fullName>
            <shortName evidence="3 5">Xylulokinase</shortName>
            <ecNumber evidence="3 5">2.7.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3 5 8" type="primary">xylB</name>
        <name evidence="8" type="ORF">Mal33_40920</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 5">
            <text>ATP + D-xylulose = ADP + D-xylulose 5-phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10964"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17140"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57737"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.17"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the FGGY kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.17" evidence="3 5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004856">
        <property type="term" value="F:xylulokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042732">
        <property type="term" value="P:D-xylose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005998">
        <property type="term" value="P:xylulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02220">
        <property type="entry name" value="XylB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000577">
        <property type="entry name" value="Carb_kinase_FGGY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018485">
        <property type="entry name" value="Carb_kinase_FGGY_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018483">
        <property type="entry name" value="Carb_kinase_FGGY_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018484">
        <property type="entry name" value="Carb_kinase_FGGY_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006000">
        <property type="entry name" value="Xylulokinase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02782">
        <property type="entry name" value="FGGY_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00370">
        <property type="entry name" value="FGGY_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000538">
        <property type="entry name" value="GlpK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01312">
        <property type="entry name" value="XylB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00933">
        <property type="entry name" value="FGGY_KINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00445">
        <property type="entry name" value="FGGY_KINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 3 5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3 4 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="1 3 5" id="KW-0859">Xylose metabolism</keyword>
    <feature type="domain" description="FGGY_N" evidence="6">
        <location>
            <begin position="3"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="domain" description="FGGY_C" evidence="7">
        <location>
            <begin position="258"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="3">
        <location>
            <begin position="81"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="241"/>
        </location>
    </feature>
    <feature type="site" description="Important for activity" evidence="3">
        <location>
            <position position="8"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU364073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV58075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="506" mass="54469" checksum="73E8D84CC7883EF8" modified="2019-10-16" version="1">MAYYLGIDVGTSGTKSLLIDAAGKVLAEAVAEYPMHQPKPGWTEQDPEDWWQATVATVRKVVRKAKAKPADVRAIGLSGQMHGSVFLDAKNKVVRPALLWNDQRTVAECDEITKRAGGRKALIKMVANPALTGFTAPKILWLRNNEPRKFDKVRKVLLPKDEIRRRLTGEFAGDMSDASGTLLLDVVKRQWSKKLLSKLELDPDLLPPVFESEQVTGQLTAAVAEELGLSTDCKVVAGAGDCAAGAIGNGVVERGVLSTSIGTSGVMFVHSDQPEYDAEGRLHTFCHAVHGQWHMMGVNLTSGGSLQWWIDNVVQGLAGIPKGKRYEAATAEAAEVAAGSGGLSFLPYLNGERTPHADPSARGAFVGLNLTHTRAHMTRAVMEGVVFAMRDSLEIIRSLNVPVDQIRVSGGGSKNPLWKQMQADIFGQNVVTLNAEQGPAYGVALLAAVGDGAYDSIGEACKATIQVKEQTKVDRKAASAMDALFPIYQDLYVALKDSFQKIASLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYH8</accession>
    <name>A0A518IYH8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative ABC transporter ATP-binding protein YbhF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ybhF_5</name>
        <name evidence="5" type="ORF">Mal33_41450</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="4"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="36"/>
            <end position="43"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV58128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="307" mass="34007" checksum="1554248A3C030076" modified="2019-10-16" version="1">MSIVETHALTKRFGDFIALDRCSLTVQSGDVFGLLGPNGAGKTTLLRTLLGFLRPTSGTASICGHDVFSESLAVRQNVAYLPGDARLPRHMRGRSVLRFFSDLHPLGSTERSLALADRFELDLQRRVGFMSTGMRQKLALCVVLSTQSPIVILDEPTANLDPSVRKAVLEQVEQIRDAGRTVILSSHVLSEIEQVCNRVVFLRRGQLVLEQSIAALKNQHRIVIWIDEDLFDIPQSLQQRVTQTSRDGDRIVLETDGDLVPLLSWLATLAPRELRLEPLGIEAIYDRVHHAETEAVGTMNDAAQEVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYH9</accession>
    <name>A0A518IYH9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HicB-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_41570</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031807">
        <property type="entry name" value="HicB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035069">
        <property type="entry name" value="TTHA1013/TTHA0281-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15919">
        <property type="entry name" value="HicB_lk_antitox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143100">
        <property type="entry name" value="SSF143100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HicB-like" evidence="1">
        <location>
            <begin position="5"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF15919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="70" mass="7651" checksum="4074605F11F0F0BA" modified="2019-10-16" version="1">MQTKYLIVIEQTPNNLSAFCPDLPGCVATGATRAEVEVRMREAIRMHLDGMQEDGEPIPAPSCVADYVEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYS0</accession>
    <name>A0A518IYS0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_42490</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="132"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="172"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="209"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="237"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="280"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="335" mass="34791" checksum="2C308DC93AAACF73" modified="2019-10-16" version="1">MPIEFPCDGCQQKLRVPDNSAGKQAKCPNCARILTIPASQTEEPAPAAPTPSNDPFDFGGPTGDQPAGDNLGAGGFGGGNFGGAAASHQNPYASPAAASQPMGSGGSGALSVQPMDPSGAVSIAWELFKLNFIVLIGAIVTQFALNFGITIVSSVIQMVILQATGDPNTPALPLINGVFGIINQVVQIWIGIGLLLLNLSVARGQKAELSLLFTGGPYLLSYIGLSILFGIGMTIGLILLIVPGIYFALTYWSTFYFLVDRNCGVFEAFRLAGEHAKGNRANAFIMGLISMGLSLLGLLACGVGLIVAAPVVGLMFTICYLQMSGQPVWQPRVAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYW2</accession>
    <name>A0A518IYW2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Protein translocase subunit SecA</fullName>
            <ecNumber evidence="10">7.4.2.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">secA</name>
        <name evidence="14" type="ORF">Mal33_42850</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell membrane</location>
            <topology evidence="10">Peripheral membrane protein</topology>
            <orientation evidence="10">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="10">Distribution is 50-50.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the SecA family.</text>
    </comment>
    <dbReference type="EC" id="7.4.2.8" evidence="10"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0065002">
        <property type="term" value="P:intracellular protein transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017038">
        <property type="term" value="P:protein import"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd18803">
        <property type="entry name" value="SF2_C_secA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01382">
        <property type="entry name" value="SecA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000185">
        <property type="entry name" value="SecA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020937">
        <property type="entry name" value="SecA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011115">
        <property type="entry name" value="SecA_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014018">
        <property type="entry name" value="SecA_motor_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011130">
        <property type="entry name" value="SecA_preprotein_X-link_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044722">
        <property type="entry name" value="SecA_SF2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036670">
        <property type="entry name" value="SecA_X-link_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30612">
        <property type="entry name" value="PTHR30612"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07517">
        <property type="entry name" value="SecA_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01043">
        <property type="entry name" value="SecA_PP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00906">
        <property type="entry name" value="SECA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00957">
        <property type="entry name" value="SecA_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00958">
        <property type="entry name" value="SecA_PP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81767">
        <property type="entry name" value="SSF81767"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01312">
        <property type="entry name" value="SECA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51196">
        <property type="entry name" value="SECA_MOTOR_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-1278">Translocase</keyword>
    <keyword evidence="8 10" id="KW-0811">Translocation</keyword>
    <keyword evidence="1 10" id="KW-0813">Transport</keyword>
    <feature type="domain" description="SECA_MOTOR_DEAD" evidence="13">
        <location>
            <begin position="1"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="11">
        <location>
            <begin position="94"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="12">
        <location>
            <begin position="448"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="110"/>
            <end position="114"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="526"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="QDV58267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="645" mass="72081" checksum="81DC2F33C112697E" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZF7</accession>
    <name>A0A518IZF7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_44460</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
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        <lineage>
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            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Rosistilla</taxon>
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    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="217" mass="24243" checksum="39C96D9D22F790AA" modified="2019-10-16" version="1">MREPLNNLNHLHRTVFVPLALCAAILLAVPGCGRLMHQLIPPSPPTSLTVNPAMLPAVKPDFLWLQVVDTVDDYFRIKTEQPLNGIDGSLETTYRVGASLLEPWNRDSTRGFERLQSTLQSIRRKAIVNVHAQQSGYSIEVVVLKEIEDVDHSQGASEGSLSLRHDGTVTRSDEIFTGEPITLGWIPLGRDTSLEQVILNEILDHVLEPDRKKLLHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZM1</accession>
    <name>A0A518IZM1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">Mal33_45540</name>
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    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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    <keyword evidence="1" id="KW-0472">Membrane</keyword>
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    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="167"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="197"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="244"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="270" mass="29903" checksum="79DF1A227E032193" modified="2019-10-16" version="1">MQSIQVEYKAPTNIPNPRLLESEIERQIRKHLKSITDVPVRDVDLKLQITQLEIRADKGTVGMIVQGAINGLQVERTVSRTDWPRRSVEPQKVLDNLISKAFKNSATLLVRLIFPSTMTRAVGNRRVSEYALRAFHECLAEVRIEIDSAIGRRPSSGQPQWQMTKSIAWKASLLAAAVVALVYWYRQGSFVDEVRPGFGCILITFGTLGCVIGAGIATLPTRFFQSEKAGRNLVKLVGVKSPTAIRVVASGIALVSTLLVVVGGYWLMFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZP1</accession>
    <name>A0A518IZP1_9BACT</name>
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        <submittedName>
            <fullName evidence="6">Di-heme cytochrome c peroxidase</fullName>
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    <gene>
        <name evidence="6" type="ORF">Mal33_45740</name>
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    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Rosistilla</taxon>
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    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
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    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004852">
        <property type="entry name" value="Di-haem_cyt_c_peroxidsae"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011045">
        <property type="entry name" value="N2O_reductase_N"/>
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        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
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    <dbReference type="Pfam" id="PF03150">
        <property type="entry name" value="CCP_MauG"/>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="CYTC"/>
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    </dbReference>
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    <keyword evidence="1 4" id="KW-0349">Heme</keyword>
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    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
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            <end position="479"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="5">
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            <end position="590"/>
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        <source>
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        <source>
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    </evidence>
    <evidence type="ECO:0000259" key="5">
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    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV58551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="590" mass="64031" checksum="D2C96009417F5D41" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZT7</accession>
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    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
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    <organism evidence="1 2">
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    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
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                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="83" mass="9321" checksum="37AB3BEE8B56C80F" modified="2019-10-16" version="1">MRRLLNSFLQSLCTAPRDPRAMDPMAMTLHDVVRLVDQERREAKLQTAPIPRAQRVLPKSQILNVAKGGVLSPLRHLAPKETA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZU7</accession>
    <name>A0A518IZU7_9BACT</name>
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            <fullName evidence="1">Uncharacterized protein</fullName>
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    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
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                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
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                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="entry name" value="DUF3500"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37489">
        <property type="entry name" value="PTHR37489"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12006">
        <property type="entry name" value="DUF3500"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="393" mass="44538" checksum="2861363B84DD3E57" modified="2019-10-16" version="1">MHRTITRFVLPVGLLGLVILAAIAQPPGFDREISEAFRGIFPGAKPEPGLFPIESTGVSTRPVMEAADAFLGTLSEPQRARTTFPVDDIEWRKWANQHSYKRQGVSFEEMNEAQRKAAFDMLQAGLSAKGLKKTQDIMKLNETLAELSGKFDEYGQWLYYITIMGEPSQTEPWGWQLDGHHLVINYFVLGDQVVMSPVFMGSEPIRADSGKFKGTVVMQDEQDKGYTFMQSLDPQQRTEAVLSSQKGGTNNLSEAFHDNIDLDYAGIPGKKLDEKQRQLLLELIAEYVGNMADGHAKVKMSEVEKHLDRTCFAWIGETDPKGVFYYRVHSPVILIEFDHQRRIAPQRGRIPVREHIHTVVRTPNGNDYGKDLLRQHYEKHDHSHPHEPAKPTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0A5</accession>
    <name>A0A518J0A5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Type II secretion system protein E</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">xpsE_3</name>
        <name evidence="3" type="ORF">Mal33_47950</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GSP E family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001482">
        <property type="entry name" value="T2SS/T4SS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037257">
        <property type="entry name" value="T2SS_E_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007831">
        <property type="entry name" value="T2SS_GspE_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00437">
        <property type="entry name" value="T2SSE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05157">
        <property type="entry name" value="T2SSE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160246">
        <property type="entry name" value="SSF160246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00662">
        <property type="entry name" value="T2SP_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T2SP_E" evidence="2">
        <location>
            <begin position="380"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="565" mass="62760" checksum="58C5AF754B1C4236" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0B4</accession>
    <name>A0A518J0B4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_47970</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="301" mass="34327" checksum="E4FF509FD0D63A30" modified="2019-10-16" version="1">MLNVDLPTKTARRIGLAILAFTALVIAGDRIGARAIDRAVMSTQFRYSQLYRGDLPGEIVAFGNSRGLHMLHPPAIAEITGQPTVNISFNALPVVAMPALWHDYLQRHPAPKRLLFEISCVSREDEAGALERFTAYMFQSPMLCETMAAYRPEEFRASQFSHLYRFNGEFAIRSLFYLRGDDQNWIMPNDATEPQIDRMLSYGAEPILYSQPHVDAARQVLEFAEQDEVEVVLFVGPFHPRYLQIIPELHEWIDWLQEELGRPIADYSAAFSENEAFSDHMHLNPRGARRLAELLHRDGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0P4</accession>
    <name>A0A518J0P4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ECF RNA polymerase sigma-E factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rpoE_8</name>
        <name evidence="3" type="ORF">Mal33_49290</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014326">
        <property type="entry name" value="RNA_pol_sigma-70_Plancto"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02984">
        <property type="entry name" value="Sig-70_plancto1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="1">
        <location>
            <begin position="47"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="2">
        <location>
            <begin position="150"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="209" mass="23578" checksum="4428FA94B41D6245" modified="2019-10-16" version="1">MANQIESDAASELFRCAADGDAESLERLLASYSGYLRVLSRMHLDRRIQHRVSPSDIVQETLLEVHRDFPSFRGNRVEEFTGWLRQVLVHNIASAVETHLVAAKRSVRAERVIESLSASIDRSHHRLASLAADPQRSPASEADHRESLAELAMALEHLPADYRTVIVLRHLDGLPFGDVADRMERSTGAVRMLWLRAIEQLRLAMEPQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0U5</accession>
    <name>A0A518J0U5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_49860</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007438">
        <property type="entry name" value="DUF488"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04343">
        <property type="entry name" value="DUF488"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="283" mass="31719" checksum="93EE74F16C974BA4" modified="2019-10-16" version="1">MLHRQKAILQLLQSVGRLVSPAELTAWAFLLRHEFPSAGGSAFYDFVPYTNGAASFALDQELGKLTDQGFLVRDEEGGFTVAAGAEFQSPDDAVQKDLSRLVERFGDGDTEKLLDYVDNAFPAYTVGSNRKRLAQRLTADPAVYTAGYEGLSIDAFLNHLVENGIRRVIDVRNNPNARRYGFHRSTLQRLTGQLEIEYLHLPELGIKADQRQHLDTIDDRKALFDRYEKSTLEENTAAIDRVAELMLQLPSVLVCLEADPVCCHRSRIAKRVAERTSLPIQNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J164</accession>
    <name>A0A518J164_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF2263 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_50970</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012664">
        <property type="entry name" value="CHP02452"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043472">
        <property type="entry name" value="Macro_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019261">
        <property type="entry name" value="PARG_cat_microbial"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10021">
        <property type="entry name" value="DUF2263"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF014899">
        <property type="entry name" value="UCP014899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52949">
        <property type="entry name" value="SSF52949"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02452">
        <property type="entry name" value="TIGR02452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2263" evidence="1">
        <location>
            <begin position="36"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="290" mass="31707" checksum="C53047A24BE7EC56" modified="2019-10-16" version="1">MSKLHFLPVVDSDELARMNQSVLEIRHEIAESIGRSALEAIDRGEYLTDTGTVDWAASIQKAKASKVSISPDALLPSVESNRYSETPVTVANQTTFAAARDLLDQGHRPLALNFANGVETGGGFLRGATAQEEALCRCSALYATLLGDPMYDFHRETDPAASSAWAILSPDVPVFRDDAGMEYDQPWLLSFITCAAPYAPAIGRARSAKMLRQRIDRVLAIAQAYRYNSLVLGAWGCGAFGNDPLQTAKDFRDALEGDFAGVFSNVIFAIADWSQQRRYLRPFSDVFSVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J197</accession>
    <name>A0A518J197_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">3-oxoacyl-[acyl-carrier-protein] reductase FabG</fullName>
            <ecNumber evidence="1">1.1.1.100</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">fabG_6</name>
        <name evidence="1" type="ORF">Mal33_51100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.1.100" evidence="1"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004316">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="245" mass="25391" checksum="731F710E2151C5FB" modified="2019-10-16" version="1">MNKQLKTAIVTGGSGAIGGAICQKLADDGFQIVVHYGSNAEGATKVVEQIVSRGGTAIKAAADVADPQQVLKLFETAEETFGGVDAVVVNAGTITKCPIVDMTIEQFDAMVSVNLRGSFLTAQEAAKRLRRNGRLIFISSGLAARPMAGTAVYSATKAALDAMTVSLSKELGERDITVNSVQPGATVPGMFEQSGDEAAKIYAAMSPLGRLGHPDDIAEVVAFVASDSGRWLTGQIVRADGGSMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1C9</accession>
    <name>A0A518J1C9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Carboxymuconolactone decarboxylase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_51770</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051920">
        <property type="term" value="F:peroxiredoxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029032">
        <property type="entry name" value="AhpD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003779">
        <property type="entry name" value="CMD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02627">
        <property type="entry name" value="CMD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69118">
        <property type="entry name" value="SSF69118"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CMD" evidence="2">
        <location>
            <begin position="46"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV59149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="189" mass="20834" checksum="F122734FA8E0B1A7" modified="2019-10-16" version="1">MTDFNVHTIESAPEASKPQLEHSQKTYGFVPNLHGVMAESPALLEAYRTVSAIFDTKTDLSTTERQIIAMTNNRLNGCTYCMAAHTSIMQAGKVPDDVITALRDGTPIADPKLEALRVFAEQVSEKRGWIEQSNIDALLAAGYTKQTVFDVIVGTAYKVLSNYTNHVAQTPLDPAFAKNEWTAETERVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1I2</accession>
    <name>A0A518J1I2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_52160</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="446"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="473"/>
            <end position="496"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="737" mass="82242" checksum="A6D83703B3A2DD16" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1T5</accession>
    <name>A0A518J1T5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 7">Pyruvate, phosphate dikinase</fullName>
            <ecNumber evidence="4 7">2.7.9.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">ppdK</name>
        <name evidence="14" type="ORF">Mal33_53210</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate</text>
            <dbReference type="Rhea" id="RHEA:10756"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.7.9.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 7 10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the PEP-utilizing enzyme family.</text>
    </comment>
    <dbReference type="EC" id="2.7.9.1" evidence="4 7"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050242">
        <property type="term" value="F:pyruvate, phosphate dikinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006090">
        <property type="term" value="P:pyruvate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008279">
        <property type="entry name" value="PEP-util_enz_mobile_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018274">
        <property type="entry name" value="PEP_util_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000121">
        <property type="entry name" value="PEP_util_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023151">
        <property type="entry name" value="PEP_util_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036637">
        <property type="entry name" value="Phosphohistidine_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002192">
        <property type="entry name" value="PPDK_AMP/ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010121">
        <property type="entry name" value="Pyruvate_phosphate_dikinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22931">
        <property type="entry name" value="PTHR22931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00391">
        <property type="entry name" value="PEP-utilizers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02896">
        <property type="entry name" value="PEP-utilizers_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01326">
        <property type="entry name" value="PPDK_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000853">
        <property type="entry name" value="PPDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52009">
        <property type="entry name" value="SSF52009"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01828">
        <property type="entry name" value="pyru_phos_dikin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00742">
        <property type="entry name" value="PEP_ENZYMES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00370">
        <property type="entry name" value="PEP_ENZYMES_PHOS_SITE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PPDK_N" evidence="12">
        <location>
            <begin position="30"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="domain" description="PPDK_N" evidence="12">
        <location>
            <begin position="310"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="domain" description="PEP-utilizers" evidence="11">
        <location>
            <begin position="434"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="domain" description="PEP-utilizers_C" evidence="13">
        <location>
            <begin position="530"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-phosphohistidine intermediate" evidence="8">
        <location>
            <position position="467"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8">
        <location>
            <position position="844"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="573"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="629"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9 10">
        <location>
            <position position="758"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="779"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="780"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="781"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9 10">
        <location>
            <position position="782"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR000853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000853-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000853-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000853-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="QDV59293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="886" mass="95976" checksum="FF157757845ACF05" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1U0</accession>
    <name>A0A518J1U0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_53320</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="128"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="171" mass="18087" checksum="C6403DD8B2DEF6E2" modified="2019-10-16" version="1">MKNEKSGMWAELRDGCAAVREVAIVGAIVLLLVAPTSFHSILERAGISSVAGVEFDLDAIEEANQQTSDAASEVDYVKEQLAMLQQQISAQATRSQSPEMLGLARSVNGLEKRLDHAKNSLGQAAVGVHSSVPARHRGGLTPPDELFKGGPSSPEVTTSRLPTSVAPTESR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J244</accession>
    <name>A0A518J244_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cyclic di-GMP phosphodiesterase response regulator RpfG</fullName>
            <ecNumber evidence="2">3.1.4.52</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rpfG_8</name>
        <name evidence="2" type="ORF">Mal33_54360</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.4.52" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071111">
        <property type="term" value="F:cyclic-guanylate-specific phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037522">
        <property type="entry name" value="HD_GYP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006675">
        <property type="entry name" value="HDIG_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00277">
        <property type="entry name" value="HDIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51832">
        <property type="entry name" value="HD_GYP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD-GYP" evidence="1">
        <location>
            <begin position="139"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="328" mass="36978" checksum="E3610F9247E781D0" modified="2019-10-16" version="1">MSVTLQSSGGKDELVSGYIPISVSTLVPSAIVGIDLFQVERDEQRYVLYRESDYPLEQTDLVKLRSRGVNKLYIRKDEQPSYQTYLREMIDNPGSDVPVSARAGALNEVVRDLLESAFREGDPDASVNTAAYLGEQTADIVCNDQFASVDLFRVLHHDYATFTHSANVAFYAGMLAAEVGFSQADVALISSGGLIHDLGKLQIPDKILSKPGRLTEQEFREIQMHPVTGFRQLVHREDLTEGQLMMVYQHHERVCGGGYPVGIAGDEIHPWAKVCAVVDVFEALTSNRPYRTPMPKRRALELLEHEREGYEQEFLECWKKITNRLWQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J276</accession>
    <name>A0A518J276_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SOUL heme-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_54750</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110165">
        <property type="term" value="C:cellular anatomical entity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011256">
        <property type="entry name" value="Reg_factor_effector_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006917">
        <property type="entry name" value="SOUL_haem-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11220">
        <property type="entry name" value="PTHR11220"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04832">
        <property type="entry name" value="SOUL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55136">
        <property type="entry name" value="SSF55136"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021773936" evidence="1">
        <location>
            <begin position="25"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="205" mass="22574" checksum="A1DA02C33D8638D5" modified="2019-10-16" version="1" precursor="true">MRKAKWIGVTALLAALVFVGKGSADYETAAYDVVEKEGEFEIRDYPELVMASTAMGASGGNGSFMRLFGYISGSNQAKQKVAMTTPVFMKPSAEQDAGSMSFVVPKQVADEGTPAPSRQDVNITKRPAGRFAVIRFSGRMNDTMREEAQQKLRDWVEAKGLKAGETMEYASYDPPFTPAPLRRNEVFLRLQTDEVQTERVQVSSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J278</accession>
    <name>A0A518J278_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Endo-1,4-beta-xylanase Z</fullName>
            <ecNumber evidence="2">3.2.1.8</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">xynZ_2</name>
        <name evidence="2" type="ORF">Mal33_54770</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.2.1.8" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031176">
        <property type="term" value="F:endo-1,4-beta-xylanase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045493">
        <property type="term" value="P:xylan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000801">
        <property type="entry name" value="Esterase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018391">
        <property type="entry name" value="PQQ_beta_propeller_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002372">
        <property type="entry name" value="PQQ_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00756">
        <property type="entry name" value="Esterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13360">
        <property type="entry name" value="PQQ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00564">
        <property type="entry name" value="PQQ"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0858">Xylan degradation</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021719061" evidence="1">
        <location>
            <begin position="29"/>
            <end position="806"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="806" mass="87015" checksum="38D78FD80A0EA62A" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ILT2</accession>
    <name>A0A518ILT2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Chromosomal replication initiator protein DnaA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">dnaA_1</name>
        <name evidence="12" type="ORF">Mal33_00010</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the DnaA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006275">
        <property type="term" value="P:regulation of DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06571">
        <property type="entry name" value="Bac_DnaA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1750.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001957">
        <property type="entry name" value="Chromosome_initiator_DnaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020591">
        <property type="entry name" value="Chromosome_initiator_DnaA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013317">
        <property type="entry name" value="DnaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013159">
        <property type="entry name" value="DnaA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010921">
        <property type="entry name" value="Trp_repressor/repl_initiator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30050:SF2">
        <property type="entry name" value="PTHR30050:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00308">
        <property type="entry name" value="Bac_DnaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08299">
        <property type="entry name" value="Bac_DnaA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00051">
        <property type="entry name" value="DNAA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00760">
        <property type="entry name" value="Bac_DnaA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48295">
        <property type="entry name" value="SSF48295"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 8" id="KW-0235">DNA replication</keyword>
    <keyword evidence="7 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="10">
        <location>
            <begin position="56"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="domain" description="Bac_DnaA_C" evidence="11">
        <location>
            <begin position="270"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QDV54060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="363" mass="39392" checksum="0403C7090919E081" modified="2019-10-16" version="1">MSDLPVLIPLSKSSTSAPRPRLAKAEPLPLLPNFVAGPENRLAAFTCQSDLSILQRGNPILLVGPSGSGKSAIARKLFEREASLLKGRGSRGIIEPAIDFARRYADAVDSDSIADFRNNFLQHPILLIEDVHLMAGKFAAQNELAARIGQRIDLDLPTILTCRRLPTEIEGIRSALASRLLPGLTIPIQLPRSEARRQIIAQYAGLREISLTEEQIGQLDNDLPADAAASRLCSAVQQLALVAMDANSDVIANDDIHDVAASFAAQQEPPIAKIARTVARRFKLKTSDLKSSSRRQQVVRARSMAMFLGRQLTRQSLQAIGQFFGGRDHSTVIHAIRSAEQLIVSDPALARVADDVSEQLKAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ILW6</accession>
    <name>A0A518ILW6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_00300</name>
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        <lineage>
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    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="40" mass="4221" checksum="6750A2DAE335AE0C" modified="2019-10-16" version="1">MWGDISRGWWRCFLLGRGAMGSVVESATTLAAGGSELGSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ILZ7</accession>
    <name>A0A518ILZ7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_00620</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
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    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="386"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="395"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="513" mass="57694" checksum="3056CE833D58CDC2" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IM92</accession>
    <name>A0A518IM92_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Arabinose metabolism transcriptional repressor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">araR</name>
        <name evidence="2" type="ORF">Mal33_01420</name>
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    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
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        <lineage>
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    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">Mal33</strain>
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    </reference>
    <dbReference type="EMBL" id="CP036318">
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="component" value="Chromosome"/>
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        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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    </dbReference>
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        <property type="entry name" value="WH-like_DNA-bd_sf"/>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="1">
        <location>
            <begin position="3"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="401" mass="44092" checksum="A03246E68C09E91B" modified="2019-10-16" version="1">MADTKYRQIADELLADITAGRFQPTGRLPSETQLVRRFDVSRPTAARALRELQNQGLIERRAGSGTFVRQQAAVVEEGQRVIGLLAPEIGSTEILEVICGDIARLARLHDCALLWGREGVHPNVNEAFADPTNAQSVTVGADPIEASRQLCDAFIQRGVPGVFFVPLEHHPDSQNLNFRITDRLRQAGIAVVLVDRDIHPFPQRSEFDLVGIDNFAAGFTAASHLLKLGCNGLLFLAPPQTAPTIAQRIAGAREAVISQEPSIRPLQVARFEPDDVDEIEKLIARFRLVADASAADARDPLDAIICSNDRVAATLMQTLAKLGIEVPRDIRLIGFDDVKYAQLLTVPLTTIRQPCRDIAMVAFRSMLDCIEKVVVPPRQYLLASQLIVRESCGAYMKPQPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMH9</accession>
    <name>A0A518IMH9_9BACT</name>
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        <submittedName>
            <fullName evidence="2">CRISPR-associated endonuclease Cas9</fullName>
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        <name evidence="2" type="primary">cas9</name>
        <name evidence="2" type="ORF">Mal33_02250</name>
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    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">Mal33</strain>
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HNHc" evidence="1">
        <location>
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            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="QDV54275.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
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        </source>
    </evidence>
    <sequence length="202" mass="23193" checksum="17384F2EA5C85C4B" modified="2019-10-16" version="1">MSTSSVLDSSVLILNRFYMAIRVVSVRRGFTLLYRQCAEVITLEDEQYTSYDFTSWCELSQLTSLEKQPGEDYIKAVGFDLRVPRICRLTRFDRLPVQSVRFNRKNLFARDSHRCQYCGQDKPSNQLSVDHVVPRSHGGKTTWENVVCCCLRCNSRKGGRTPSQANMNLLTTPIKPKFNPVLTQPIVDPRYECWKTFLPAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMY3</accession>
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        <submittedName>
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    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
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                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
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                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd07389">
        <property type="entry name" value="MPP_PhoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018946">
        <property type="entry name" value="PhoD-like_MPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038607">
        <property type="entry name" value="PhoD-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09423">
        <property type="entry name" value="PhoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022226320" evidence="1">
        <location>
            <begin position="24"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="domain" description="PhoD" evidence="2">
        <location>
            <begin position="54"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="354" mass="39407" checksum="E06AD97C25502D0F" modified="2019-10-16" version="1" precursor="true">MMSRIWNPCFIGLLILAPLVVSAEQPADKASTDTAIRRVLFGSCIKQDDPTPIFPVMLRTEPELLLFLGDNIYADTSDMDVMRAKYAKLASNDGFKALTSGAQVMATWDDHDYGVNDGGATYPQRVAAQQAFLDFWGEPADSPKRQRPGIYEAKRFGPPGKRLQVIMLDTRYFRSPLKTGPRQLGGPYVPDNDPEKTILGEAQWKWLEEQLRKPADLRVIASGMQVVAESAGQETWANLPHEQTRLFDLVQSTAAGGVIFVSGDRHWAEMSIASNGVAYPLLDATSSSFNQKHPRGTPTRNRFRAIKQTYHEENFGVINIDWDAADPTVTIEVRDLAGKAQLEKTVRLSELQPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMZ9</accession>
    <name>A0A518IMZ9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Bacterial membrane flanked domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_04250</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005182">
        <property type="entry name" value="DUF304"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03703">
        <property type="entry name" value="bPH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="123"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="bPH_2" evidence="2">
        <location>
            <begin position="147"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="228" mass="24621" checksum="6822C7CABAD23BB2" modified="2019-10-16" version="1">MQVLTAQCPYCQNKVDSTIEHLDGPVVCPECAKPFEIEIPTAVVTSVQEVGRESVNADRMAAEPSERTLAKVHPVVFRARPLASLILGALFLVSLVVLIASLAGASIAGYAFDENAMLGPASLVTWVCGIVLLAIAGVVGFWMLVSRFTTLTVTDDRTIYQEGIISRATSEVQHNDVRNIQLDQSFTQRLLNIGGVGISSSGQDDLEVVARGLPHPERIIRLIRENQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IN66</accession>
    <name>A0A518IN66_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Uronate isomerase</fullName>
            <ecNumber evidence="4">5.3.1.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">uxaC</name>
        <name evidence="6" type="ORF">Mal33_04920</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>D-glucuronate = D-fructuronate</text>
            <dbReference type="Rhea" id="RHEA:13049"/>
            <dbReference type="ChEBI" id="CHEBI:58720"/>
            <dbReference type="ChEBI" id="CHEBI:59863"/>
            <dbReference type="EC" id="5.3.1.12"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate metabolism; pentose and glucuronate interconversion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.12" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00246"/>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008880">
        <property type="term" value="F:glucuronate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006064">
        <property type="term" value="P:glucuronate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003766">
        <property type="entry name" value="Uronate_isomerase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02614">
        <property type="entry name" value="UxaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV54537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="428" mass="48553" checksum="B7C657F3D9FEED02" modified="2019-10-16" version="1">MTSELRQRIYQQLASVELIDPHTHINPLDAGSHTLVDILGYHYYTELAHSAGMPREQIEDPAISAKEKVGRLIEGIGPIDNTIQYSWLIDICQRFFGFEGDRLDASNWEALFDSSEAQMADAGWSDEVLRRSNVKSVFLTNDFDDPLAGFDTAKYVPCLRTDDLVFHLGKPEVRQRLEAATKVSVGSWTELREAIGVLFEHFTTNNARACAISIPPSFAPEPVSDGRVETALDAVLKDGVNADESHLRALSHRIFWTLAEMCDQYELPFDLMIGVNRGVYPTGVFQGQDLYDSRVSLIQYQQLLNAFPRVTFPISVLASVTNQELASYAWIFPNVVTNGHWWYSNTPSIIERDAAHRLEAVPRTKQIGYYSDAYKLEFVAPKFDMYRKILAKVLEEYYVIDRSWSEERAVEFGTQVLRGNVETTFKIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IN90</accession>
    <name>A0A518IN90_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_05020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011453">
        <property type="entry name" value="DUF1559"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07596">
        <property type="entry name" value="SBP_bac_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="292" mass="31713" checksum="2CC43E131E7C146C" modified="2019-10-16" version="1">MKTIKNRNAFTLVELLVVIAIIGILVGLLLPAVQAAREAARRMQCSNNIKQMGLALHNYHDTHNSLPPGWIDDSTNQNRMGWMTYILPYIEQTAIHDGMKNVGAYDVPWYNLPEMTTGTTDVPDPYAKMVLDAYVCPSDPSRGTNEALGGYGKSNYTGVGGAHYLASGGANGTFYDHSFVRFRDMTDGLSNVMSVGERSTVEQASRSWLKRGTIWIGAYSAGTYYHNNAISSASTYYSINGAAGSYNFTSAHPGGVQFLFGDGSAHFISETIDLVTYRNLGSINDGSPVSGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INH4</accession>
    <name>A0A518INH4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">VanZ like family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_05990</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006976">
        <property type="entry name" value="VanZ-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04892">
        <property type="entry name" value="VanZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="domain" description="VanZ" evidence="2">
        <location>
            <begin position="43"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="144" mass="15660" checksum="C810F18799A772C8" modified="2019-10-16" version="1">MRQIITTTVLGMRLASLTLVAYWSVIFTGTHIPSVRLPSFSNADKAYHFAAFTGLAILLAWALPKSRRHPRRHLLIALGIGVAYAIFDESTQLLVRGRSAEVLDFVADCGGLLTGLFVYSVLRSLITPPAPKLHQPSCGGRVGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INR2</accession>
    <name>A0A518INR2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Phospho-2-dehydro-3-deoxyheptonate aldolase</fullName>
            <ecNumber evidence="5">2.5.1.54</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">aroG</name>
        <name evidence="7" type="ORF">Mal33_06870</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 5">Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>D-erythrose 4-phosphate + H2O + phosphoenolpyruvate = 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14717"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16897"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58394"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="2.5.1.54"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 5">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 1/7.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 5">Belongs to the class-I DAHP synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.54" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00084"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003849">
        <property type="term" value="F:3-deoxy-7-phosphoheptulonate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006218">
        <property type="entry name" value="DAHP1/KDSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006219">
        <property type="entry name" value="DHAP_synth_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21225">
        <property type="entry name" value="PTHR21225"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00793">
        <property type="entry name" value="DAHP_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001361">
        <property type="entry name" value="DAHP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00034">
        <property type="entry name" value="aroFGH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DAHP_synth_1" evidence="6">
        <location>
            <begin position="39"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR001361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV54727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="349" mass="38122" checksum="2272A9A9EC075C3E" modified="2019-10-16" version="1">MTQTTDDLRIRDQKSLRSPADLIAEIPVSETAANTVYQARQQFHQALEGTDDRIAVVVGPCSIHDPDAAIEYAAKLQKAQQRLSDDLLVIMRVYFEKPRTTVGWKGLINDPRIDGSFEINQGLQTARKLLLDINEVGVPAGVEYLDLISPQYIADLVGWGAIGARTTESQGHRELASGLSCPVGFKNGTAGSVQIAVDAIGAARNSHHFLSVAKDGRSTIFQTTGNEDCHLILRGGNTHTNYDAASVDDAAALLEKAGLDPRIMIDCSHANSRKRHERQAYVCRDICHQISEGDRRIIGVMIESNLVEGKQSKPEQRGQSITDACIGWDDTVTLLDRLATAAKERRAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INS8</accession>
    <name>A0A518INS8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_07060</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="189" mass="21009" checksum="A4CEFFF211E93D7F" modified="2019-10-16" version="1">MIAATLPRQLTMQHECRWRHTILATKKDINLGFYLVQNDETAGWMGGYLVLNSSGRPLEFHCSLPLRPTRTQQILYGPSLGAYLVGDLIGKALLDRAKMKTQLVLADNVDALPLARRSGIPFACTEVSKRANIDDVIEVDGWQAIASPGQRDEVMEILQKLPATFDLNEPFDRIREAFSEARGTSRAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INU8</accession>
    <name>A0A518INU8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">GYF_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_07100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025640">
        <property type="entry name" value="GYF_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14237">
        <property type="entry name" value="GYF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GYF_2" evidence="1">
        <location>
            <begin position="17"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="149" mass="16833" checksum="253D128191388387" modified="2019-10-16" version="1">MPNSLSDKGVVFSMSQWFIQQDAETELGPLRPSELLDLVRQGVVTRETLCRKENSPWCHAQDVGGLFRAAESQVVGYRCPYCQKSVNEPPTYCKGCNKYVDEGIEILRDARGRKLEGKAQAFDTPKESTASWTSWVTKLKSQRSKRNNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INV9</accession>
    <name>A0A518INV9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Tetratricopeptide repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_07020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="244" mass="27145" checksum="917470574C7CF9CF" modified="2019-10-16" version="1">MLPFLLALTLLQPVKTIGQWEGEGYRALRDGNLDRVAEIAKKIEDQHPASFSAAMARGSLLLRAGMAKESLIAFDEAAKLQPAQIPYMWQRGIAQYYAGEFVAGRRQFVVHREVNAHDVENAVWHYMCVARVEGVDAARREYLPAPGDSRVPLQEVYDLFAGTATIQTVTDAIDAIPAQSRGAASAQFYGWLYLGMYEDAQGNLAEARKWLEKAVALKQTHYMADVANVHLQQVVARIEKPAEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INX9</accession>
    <name>A0A518INX9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_07620</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021705049" evidence="1">
        <location>
            <begin position="29"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="380" mass="41520" checksum="A153B6F21FE0A2F2" modified="2019-10-16" version="1" precursor="true">MMSKWRRNATLSPLASIPLSLLMFLHGATLCVGQQQDLAAFSKIGPEGAGHADAIAAAKRLSQLGPDRLIDVLAAIESATPLGRNWLRVIAADIADNGQVPVQPLAAFIKNTDGSRDARYVAFRLLKDADPDLADSLVDGMLNDPSLQLRYEAVAKVLEAAKAAEGDARVALYQQALESARYPGQLTEIAKSLREAGHPVDLAAHMGFIKQWQLVAPFDNTDGVGFAAVYAPEKEYLESPQHTVSQTSYAGKLDKVSWQSQSTDDELGMLDLNPVFKNEKAAVCYGYFEIESPAEQPAQLRLGSIVANKIWVNGKLATANEVYHARTGVDQYIAEVPLRKGKNTVLVKICQNAQTQSWAQVWEFQLRITDPNGNPLHFER</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
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    <name>A0A518IP35_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">FG-GAP repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Mal33_08220</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013517">
        <property type="entry name" value="FG-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013519">
        <property type="entry name" value="Int_alpha_beta-p"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028994">
        <property type="entry name" value="Integrin_alpha_N"/>
    </dbReference>
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        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
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    </dbReference>
    <dbReference type="InterPro" id="IPR011519">
        <property type="entry name" value="UnbV_ASPIC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13517">
        <property type="entry name" value="FG-GAP_3"/>
        <property type="match status" value="2"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0802">TPR repeat</keyword>
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        <location>
            <begin position="108"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="UnbV_ASPIC" evidence="5">
        <location>
            <begin position="921"/>
            <end position="985"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV54857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1007" mass="108354" checksum="92130E7B15A3FC77" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP58</accession>
    <name>A0A518IP58_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_08440</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
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            <taxon>Rosistilla</taxon>
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    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="103" mass="10802" checksum="A2B5BA9AEFA47BA6" modified="2019-10-16" version="1">METFFVACPSGHQVPVSINHSDAPVQCPQCDGMLESGMPRTSLSDTGAMRILEASELAPPAPKSATASRPCPICRTPVSEASAACAHCQTYLASPPDFLRDLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP69</accession>
    <name>A0A518IP69_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Lysophospholipid transporter LplT</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">lplT</name>
        <name evidence="7" type="ORF">Mal33_08600</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="47"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="104"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="144"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="175"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="230"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="267"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="295"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="333"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="365"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="398"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="9"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV54895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="442" mass="47278" checksum="8E8F8B2B1B6674BB" modified="2019-10-16" version="1">MKSNLIKRGFLSLLAAQFLGAMNDNVLKMLLTFMVIDGAWAGMLGDGGQGIVGICFTIPFILLSGYGGQIADRYSKREVTLWVKIAEVPIALIAMVGFYLGNLWITLLALVALTCQSSFFGPAKYGMIPELVDDTDLSRANGTINMMTNVAVIVGTLLGGVVADRYSPQDASLTPIQWLPGAALLVIAISGLISAVFMPRLEPGDRSMKFDWNPFATYLGSIQEMAQSRFLMVMMAWGYFYLLAGLALLILPEYTVVLGIDRTEASVLLGVMGVAIGVGCAVAGLISGHQINPKLVPIGAAGLVFFFLLLAFVTPTLPDQGPMVRVALSNTAGFVFGAGFFAGFYIIPLQSLLQKLSPDNERGRFLGTANALSFTFLTIASLMYWAIRPLFGDQPQRIFAVCAAMMAAGAAFFLWRLRGTGILIGSKSTDVESAPAVAESAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPI5</accession>
    <name>A0A518IPI5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Flagellar MS-ring protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Mal33_09480</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Bacterial flagellum basal body</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the FliF family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009431">
        <property type="term" value="C:bacterial-type flagellum basal body, MS ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003774">
        <property type="term" value="F:cytoskeletal motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013556">
        <property type="entry name" value="Flag_M-ring_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000067">
        <property type="entry name" value="FlgMring_FliF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006182">
        <property type="entry name" value="FliF_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043427">
        <property type="entry name" value="YscJ/FliF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30046">
        <property type="entry name" value="PTHR30046"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30046:SF0">
        <property type="entry name" value="PTHR30046:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01514">
        <property type="entry name" value="YscJ_FliF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08345">
        <property type="entry name" value="YscJ_FliF_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="13" id="KW-0966">Cell projection</keyword>
    <keyword evidence="13" id="KW-0969">Cilium</keyword>
    <keyword evidence="13" id="KW-0282">Flagellum</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="domain" description="YscJ_FliF" evidence="11">
        <location>
            <begin position="82"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="YscJ_FliF_C" evidence="12">
        <location>
            <begin position="251"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="270"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="376"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="273"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="387"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF08345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="QDV54980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="553" mass="60460" checksum="157E172509396302" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPJ9</accession>
    <name>A0A518IPJ9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF58 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_09930</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002881">
        <property type="entry name" value="DUF58"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01882">
        <property type="entry name" value="DUF58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF58" evidence="1">
        <location>
            <begin position="45"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="295" mass="33121" checksum="449C63CAF73474DB" modified="2019-10-16" version="1">MYQTFAKYLDHDAYTALNALRLKSRHRFAGSAAGEHRSFRMGQAIEFAQHRQYAPGDDLRYLDWKIYGRTDKYYLKQSEDETDLCCYVLLDNSESMSFAGTDSEISKLQYARRLAVALAFVTLAGQDRIGLGMLSDRLFDYLPPSSAISQLSRWDEVFEKTSAAGGTDLPSGVAQFVDQARQPGLVVLISDLLGPEQGLQGALTLLRGAGHDAIVLHVMDRQEREFRFDGELHFEGLESAGEVDVNGAQIRNAYLEELDNFIEKQRQNCWGLGFEFSTVLTDFPLAAALSSHFRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPT8</accession>
    <name>A0A518IPT8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RNA polymerase sigma factor SigY</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">sigY</name>
        <name evidence="3" type="ORF">Mal33_10620</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sigma70_r4_2" evidence="2">
        <location>
            <begin position="127"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="166"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="187" mass="21341" checksum="EF38970F5224C18E" modified="2019-10-16" version="1">MTLSDIDRQLLDRCLDNEPQSWEAFIDRFLGLVVHVVNHTATSRGVTLPVAERDDMVAEVFLTLVNNDRAVLRRFRRQSSLATYLTVIARRVIVHQLATAQRNAAQKNRIASEETLISPVEQQIEDRDQLEQLLSRLDPKEADVVRMHHLEGKTYREIGNHLGLPENSVGPMLSRARDKMRQSQPGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPU3</accession>
    <name>A0A518IPU3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">All-trans-phytoene synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">crtB_2</name>
        <name evidence="2" type="ORF">Mal33_10840</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004311">
        <property type="term" value="F:farnesyltranstransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016117">
        <property type="term" value="P:carotenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00683">
        <property type="entry name" value="Trans_IPPS_HH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002060">
        <property type="entry name" value="Squ/phyt_synthse"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019845">
        <property type="entry name" value="Squalene/phytoene_synthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044843">
        <property type="entry name" value="Trans_IPPS_bact-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033904">
        <property type="entry name" value="Trans_IPPS_HH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00494">
        <property type="entry name" value="SQS_PSY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01212">
        <property type="entry name" value="Phytoene_synthase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="SSF48576"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01044">
        <property type="entry name" value="SQUALEN_PHYTOEN_SYN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="320" mass="36293" checksum="4A5CA1472F4DCA5F" modified="2019-10-16" version="1">MNNAPASINASYAAAARVARRAASSFYPSFWLLPRPKRQAMCAFYAFARLTDDAADAPGEIAEKRHWLDAWRQTIEATLAGDPLPAASTFHSAGPESRKRSDLGMQILPALRHAQKRYAIDPTLLIEIIDGAIADQQERSITTQQQLDIYCYQVASTVGLVCLQIWEFQGEATRQAAIDCGKAFQLTNILRDVREDLGRGRCYLPQTDLQRFGVDLQRPADEQAAAWQGLLVDYCERAETLYQQGWRAWEGIDPDGQPMFSMMWHNYHALLQTIRQQPLLVLQQRIRLPWRQKLNIAASHFVPGYPRRLTLAQPRRDEGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPU6</accession>
    <name>A0A518IPU6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_10720</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="139" mass="15380" checksum="696EC2B45161CB97" modified="2019-10-16" version="1">MSDHREAFATFIKPFAEFPALQQRVLEVLESLPANVQLDFASDPRFDVAIEDYQPGKGSRLFIASPGAVGKGSRCVVLRPKLDRASEAFAKYVIAHEFAHAHLHNGGWGEITDIEQAADALAASWGFDRPEQTGWAWLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPV4</accession>
    <name>A0A518IPV4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_10940</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021898173" evidence="1">
        <location>
            <begin position="24"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="223" mass="24600" checksum="11BFCFF1AA065F94" modified="2019-10-16" version="1" precursor="true">MSPRYLFTAVVLLALGFASIASAQRPGRGARPTGDSSVSDPELLGLHKEFVSKAEKLAAEYERKKNLDGAREVYESMTRLIPEYEAAQLGLKRILNAQSTQDRKVVEVQANRDWQDTQIILVKGNPVHIEAKGTWFVVNETDANGLVIPKEIDPKNNKIKLGTLIGMIVSQPDVSKLKPFPIGNGTDFIAPETGRLVLRMFDVEPRDNKGSMSVLVQSTFGRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPX7</accession>
    <name>A0A518IPX7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Thiamine pyrophosphate-containing protein YdaP</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ydaP</name>
        <name evidence="7" type="ORF">Mal33_10890</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the TPP enzyme family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012000">
        <property type="entry name" value="Thiamin_PyroP_enz_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012001">
        <property type="entry name" value="Thiamin_PyroP_enz_TPP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011766">
        <property type="entry name" value="TPP_enzyme-bd_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00355">
        <property type="entry name" value="Rieske"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02775">
        <property type="entry name" value="TPP_enzyme_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00205">
        <property type="entry name" value="TPP_enzyme_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02776">
        <property type="entry name" value="TPP_enzyme_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="SSF50022"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
        <property type="entry name" value="RIESKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="Rieske" evidence="6">
        <location>
            <begin position="6"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV55120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="652" mass="70155" checksum="81656B39AB656186" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQ60</accession>
    <name>A0A518IQ60_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_11980</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="58" mass="6294" checksum="5750152B6EAE1668" modified="2019-10-16" version="1">MLTDQHEIKNSIAPFPSTKAPNCGESSAKKLLATIMQKSWSDKSTRSIAPPSIRPTPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQ74</accession>
    <name>A0A518IQ74_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Imidazole glycerol-phosphate synthase</fullName>
            <ecNumber evidence="5">4.3.2.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">IGP synthase cyclase subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">hisF_1</name>
        <name evidence="12" type="ORF">Mal33_11920</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + L-glutamine = 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate + H(+) + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24793"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58278"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58475"/>
            <dbReference type="ChEBI" id="CHEBI:58525"/>
            <dbReference type="EC" id="4.3.2.10"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 5/9.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Heterodimer of HisH and HisF.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the HisA/HisF family.</text>
    </comment>
    <dbReference type="EC" id="4.3.2.10" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000107">
        <property type="term" value="F:imidazoleglycerol-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd04731">
        <property type="entry name" value="HisF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006062">
        <property type="entry name" value="His_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004651">
        <property type="entry name" value="HisF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00977">
        <property type="entry name" value="His_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7 11" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="8 12" id="KW-0456">Lyase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QDV55222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="263" mass="28358" checksum="C8B4F6A578AAB12F" modified="2019-10-16" version="1">MLRSRIIPCLLIDNRGLVKTVGFKDPKYVGDPLNAVRIFNEKEVDELVVLDIRASAEKREPDFKMIENLAAECRMPLCYGGGITNADQAKRIVSLGVEKVAISSAVVRDSTLVTRVAEAVGRQSVVVVVDVKRSMFGRYALFTGNGKVKSKQDPFDFALLAQQAGAGEIVVNSIDNDGTMAGYDLKLAQRMREIVDLPITVLGGAGKLTDIASLVQRFGLVGAACGSFFVFKGKYRAVLISYPTAQQKEEILNPVASATTAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQ87</accession>
    <name>A0A518IQ87_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_12240</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011447">
        <property type="entry name" value="DUF1552"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07586">
        <property type="entry name" value="HXXSHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="451" mass="50084" checksum="E6E178342DD3ED65" modified="2019-10-16" version="1">MNRNAFSATTSSKRTQGVNRRLFLRGTGAALGLPFLASSKWLRGSETATPPLRNAFIYFPNGVWEKAWVPEKTGSDYQLTPSLEPIEAIRNKVLVLTGLDKKHSHGGDGHYAKTANFLTGMPVAKTTGKNISSGGVSVDQLIAQHNSGLTPIPSLELGTEPVISGIDSNVGYTRLYGSHISWQSPSRPVAKEINPRVVYERLFGQKQAKGALANSNLLDYVLEDARRVRKTLGRDDQFKMDEYLDSVRSVERRIEYAMREDPRQWQPTLDAAQIAARRPGAPAEFREHIDVMLDLMVLAFQTDSTRVCSMMFANDVSGRNFSFLDGVKGGHHELSHHENNEKKIDQYQRINRWHVEQFTKMIQKMDAIQEGEGTLLDHSMIMFGSSFSDGNRHDPDNLPILLAGGGSTGIQSGRHLAAEGQVPLCNLYLSMLRRNGIELESFGDSNAELSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQG7</accession>
    <name>A0A518IQG7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Ribitol 2-dehydrogenase</fullName>
            <ecNumber evidence="1">1.1.1.56</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rbtD</name>
        <name evidence="1" type="ORF">Mal33_13090</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.1.56" evidence="1"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050255">
        <property type="term" value="F:ribitol 2-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="315" mass="34477" checksum="7CE0EAD518840643" modified="2019-10-16" version="1">MTTKNSFGPQGWTPDRLGSLAGKTYVITGANAGAGFEATRVLLSKGATVVMMNRSADKSAAAIATLKQEFGSSADVTFVRMDLAVLDSVREAATELLEKVPRIDAFICNAAIAQVARQQITVDGFESQLGVNHFGHFLLSGLLFDRIEASAGRIVVVGSNAYKMGLKRIQFEDLNFDTNYTAWSSYAQSKLAQMMFAYELQRRVEAASKNVTVLVCHPGASRTNLLKDTASTFNKIVWSILSRIIAQSAEKGSWPEVMCATEEKVEPYKLYGPTKRSEMVGPIGECPLHECALNQEAAAKLWILSEQKTSRYWSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQK1</accession>
    <name>A0A518IQK1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_13370</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="131" mass="14060" checksum="A0D7BA15FF878F4F" modified="2019-10-16" version="1">MRLTKFIPLLPSGLLILGIYGCNSPEPDPKMPPATPASDTTEDHANHDHGDHATVDADSPMAKMMPGLKELSPEDYKSAMAQHVCPVSGEMLGTMGAPEKVDVNGKSVWICCDGCNDKLLANPEKYLAKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQP0</accession>
    <name>A0A518IQP0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_13770</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd08026">
        <property type="entry name" value="DUF326"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044543">
        <property type="entry name" value="YHJQ-like"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="110" mass="11888" checksum="4E9E677423493B04" modified="2019-10-16" version="1">MSTATASMKECLQNCQECQTTCADMLTSHCLSEGGDHVEQTHVKLMLDCIAACAACVDFMSRNSDHHALYCRACAEICKACADSCDKVGNMDKCVECCRKCHESCSSMAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQU8</accession>
    <name>A0A518IQU8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Choline-sulfatase</fullName>
            <ecNumber evidence="10">3.1.6.6</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">betC_3</name>
        <name evidence="10" type="ORF">Mal33_14390</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="PTM">
        <text evidence="7">The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sulfatase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.6.6" evidence="10"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047753">
        <property type="term" value="F:choline-sulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004423">
        <property type="term" value="F:iduronate-2-sulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16030">
        <property type="entry name" value="iduronate-2-sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035874">
        <property type="entry name" value="IDS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024607">
        <property type="entry name" value="Sulfatase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00523">
        <property type="entry name" value="SULFATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0106">Calcium</keyword>
    <keyword evidence="5 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021891987" evidence="8">
        <location>
            <begin position="33"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase" evidence="9">
        <location>
            <begin position="37"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="modified residue" description="3-oxoalanine (Cys)" evidence="7">
        <location>
            <position position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR600917-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV55465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="504" mass="55923" checksum="DD87837D61BE10F7" modified="2019-10-16" version="1" precursor="true">MHLPHFSALPRGRFLFLAIAGLVAAQAMRADADDSRPNVLFIVSDDLNNSLGCYGHPIVKSPNIDRLAARGVRFDRAYCQYPLCGPSRNSMLTGLYPNSTGIHANSLIFRQTIPRHHSLSQAFRLDGYFAGRIGKLYHYNVPKSVGTNGHDDPGSWELELNPAGCDRLEEEPQIFSLRKGSFGGTLSWLASSRPDEDHTDAMLADDAHWVLQRCAKRRDRPFFLAVGFYRPHTPYVAPKKYFEPYPLDQMPVVQGWEEDQKDIPKLGLGSHKKDHELLTDDLRRQAIQAYYASISFMDAQVGRLLDSLDELGLADNTIVVFTSDHGYHMGEHGLWQKMSLFEESARVPLIIAGPGVAQPGSVAKSPVGLIDLYPTLAKACDVPSPENLQGQDLQPMLADPSAKGRGWTISQVKRGGKPPVFGYTIRTPDWRYTQWGDKGANGEELYDHRSDPQELTNLANDSAHSATIADLKQKIEQAIGQTFPESGEIPSVRNAVWAPNLTDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRA2</accession>
    <name>A0A518IRA2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF1080 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_16040</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010496">
        <property type="entry name" value="3-keto-disaccharide_hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06439">
        <property type="entry name" value="DUF1080"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021769795" description="DUF1080 domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1080" evidence="2">
        <location>
            <begin position="27"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="391" mass="43013" checksum="C8A0699B68E08CF2" modified="2019-10-16" version="1" precursor="true">MHRSWIVALVLLLAPTANLWSQQKDDGFVPMFNGKDLSGWQLVNTDPRTWSVEDGMLICSGKPIGELRTDRMYQNFIMEVEWRHMVPKGNAGIFVWADDITAKGQPFHRGIEVQILENAYGKADWFTTHGDIFPIHGAKMTPVNDRGGSRAFPTEMRSLPTPQWNHYRIEAIDGAISLAVNGKVVTRGTDCNPRKGYLCIESEGGVVHYRNAKIKELPDTPIEANMVAIADRGYRCLYTGIDLTGWNVQQPEGAAKQTAEEAAGHWKPSDWVLSCTGATGENLPLATDEAFGDYGFVVDFRLNKDSGSPQIRLRGDAAAITIAGDHSPLTPHLDKVGKWNRIEGEVRGDKVSLTINGNEIEPFAATGSADAKGPLTLVPDGPVDFTNIFVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRE4</accession>
    <name>A0A518IRE4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATPase RavA</fullName>
            <ecNumber evidence="3">3.6.3.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ravA_2</name>
        <name evidence="3" type="ORF">Mal33_16390</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.6.3.-" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011703">
        <property type="entry name" value="ATPase_AAA-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041628">
        <property type="entry name" value="ChlI/MoxR_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07726">
        <property type="entry name" value="AAA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17863">
        <property type="entry name" value="AAA_lid_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_3" evidence="1">
        <location>
            <begin position="39"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="AAA_lid_2" evidence="2">
        <location>
            <begin position="232"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="313" mass="34553" checksum="3165BC6876EE977B" modified="2019-10-16" version="1">MIDVAFSTAQRLQANMEKVVLGKPEVVRSLLIAVLAGEHVLLDDVPGVGKTLAAKALARSLDGVFTRVQFTPDLLPSDIVGSNLYRTDLHEFEFNQGPVFANVVLADEINRAPPRTQSALLEAMSEGQVSIDGTTRPLPKPFTVVATQNPIEFEGTYRLPESQMDRFLLRTSVGYPQPDVERDVLRSHCDGEPVEQLSPVVSCEEVLQSQEAVRRVRFEDSLISYLLAVVDATRQSEDLQVGVSTRAALSFFRGCQARAVCMERDYVVPDDIKSLAVPVLSHRVVLKDSFMTGDRLRAEQIVGEIVHRVTVPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRH3</accession>
    <name>A0A518IRH3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Multidrug resistance protein D</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Mal33_16600</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="87"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="123"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="174"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="209"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="281"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="315"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="345"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="370"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="432"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="7">
        <location>
            <begin position="52"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="238"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV55681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="468" mass="49952" checksum="8ECE06D8B647FBA8" modified="2019-10-16" version="1">MSDSDLSLLGRASPVIAEGVCDIQPNELLALTTSIHTPALRVPQGFFYGYLMVPVASLAQICTAPGQTFAISAFIPAIRDSLQLSEISLTSAYMIGTLVAAFPLMLVGPIADRIGNRATITGIVLLLAGACFFASFVNSFATLLLAFLALRFLGQGSLSLLSSNTTSMWFRAKLGRVSAIMSIGMAGAFAVIPGWLLSSIESYGWRETYRGLGLVVAGIMLPLLAIVYRNRPEDVGQHLDGNRPDEPLPHAEGSRATGSQRTVAIEERSLSLRDAMRQPTFWILMTIMSAWAMIGTGLVFYLFAIGEARGIDKDATAAVFKTFALSMLAMQFSGGFLADRFALHHLLFAGVGLLSLGTLTLFFAQTSPQLHLFGLLFGAGQGITVAVNATVWVRYYGRAHLGKIRGTSWSASVAGSGAGPFLLGWAKDHSGHFEPAIIAFLCILIPLVLLALWVRPPARPDVLAPAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRI0</accession>
    <name>A0A518IRI0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_16850</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="530"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="104"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="338"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="478"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV55706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="575" mass="61269" checksum="55ACB62C75900F26" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRI8</accession>
    <name>A0A518IRI8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_16730</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="81" mass="9098" checksum="B536904F75D49FA6" modified="2019-10-16" version="1">MERSLPDAATSLYWSDPVRQLGLNGQRFPQNASKSGFDHVSRSRHPPSILQHLNPLPAGLLPHPFKVTHLPSDRQECLLHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRP9</accession>
    <name>A0A518IRP9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Polysaccharide deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_17470</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036278">
        <property type="entry name" value="Sialidase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50939">
        <property type="entry name" value="SSF50939"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="SSF88713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NodB homology" evidence="1">
        <location>
            <begin position="446"/>
            <end position="672"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="672" mass="75162" checksum="1A7BAFAE03A57BA9" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRR4</accession>
    <name>A0A518IRR4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_17500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="173" mass="19573" checksum="627EB98D7C767303" modified="2019-10-16" version="1">MVAFRSAKVRATILTFHPHFRGAKGDHLATLDSDQLTKEHDERHCNIQTSPCVTLNGDNGGTKAYQHEAQASVPSKITRSRFVRVWSPFAPRKCVHQSLFPSALSRSERRPSATLDSDRLTKEYDERYRNIQTSPSVTLNGDNDGAEAYQHEAQVLMLRVDGVASENWYCKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRT9</accession>
    <name>A0A518IRT9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_17700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010869">
        <property type="entry name" value="DUF1501"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07394">
        <property type="entry name" value="DUF1501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="467" mass="51092" checksum="23B7D0166B2BAAE4" modified="2019-10-16" version="1">MHTINRRESFFRLGTSLGSIAAAAMALDDAHANDSAAAPLAPKAGHFPAKARNCIFLMMEGGPSHIDTFDPKPSLSKLHLKEFTRQGEQKSAMESGKRYYVESPFRFGKHGESGADMADNWTHLSKLADDLCFYRGCQVDSVNHPTAMYQMNCGNRFGGDPGLGAWVTYGLGSENQNLPGFLVLPEVSYPQGGAANWSNGYLPAFYQGTPLRPKGSPILDLQPPPGVTAARQRANLDFLNKLNADHAAKHPAHDDLNARIESYELAFRMQMEVPDAIDLSGEDAKTLDLYGIGGEATDAFGRKCLLARKMVEKGVRFVQLYNGSWDSHDYIERAHGNLVRSVDQPIAALIQDLKQRGLLESTLIVWCGEFGRTPDNGVRGGVAYGRDHNPNAMTIWMAGGGCNAGHTIGATDELGMTAVENVHHVRDFHCTLLRLLGLDDNKLTYYHAGRFKQLSQFGGKVIDELIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRU7</accession>
    <name>A0A518IRU7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aminodeoxychorismate synthase component 1</fullName>
            <ecNumber evidence="3">2.6.1.85</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">pabB</name>
        <name evidence="3" type="ORF">Mal33_17890</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.6.1.85" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046820">
        <property type="term" value="F:4-amino-4-deoxychorismate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044249">
        <property type="term" value="P:cellular biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005801">
        <property type="entry name" value="ADC_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019999">
        <property type="entry name" value="Anth_synth_I-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006805">
        <property type="entry name" value="Anth_synth_I_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015890">
        <property type="entry name" value="Chorismate_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11236">
        <property type="entry name" value="PTHR11236"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04715">
        <property type="entry name" value="Anth_synt_I_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00425">
        <property type="entry name" value="Chorismate_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00095">
        <property type="entry name" value="ANTSNTHASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56322">
        <property type="entry name" value="SSF56322"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Anth_synt_I_N" evidence="2">
        <location>
            <begin position="35"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="Chorismate_bind" evidence="1">
        <location>
            <begin position="225"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="485" mass="53302" checksum="4AE08CECD5532E7F" modified="2019-10-16" version="1">MVIPTPADLHPATPDFTSAGDCPLVAPLPPQTDLREVFLRLCHLPHCLWLDSAKPMPDLGRYSFLTADPIEIVSATDDDADPLAKLQKFIPLLSQAAAPGLPPFQGGLAGVLGYELGRTLEPIPAPRFNDLPTPPLCVGLYDWTIAVDHQQNRGWIISQGWPETDPDRRRVVAARRMQQIQWWLGCTPTAMPRPPRSAPRAHDAMAPQFRTPIDPSLTSNFAPGEFRTAVGDVIDYIRRGDAFQVNLAQRLLYPDQHGAVAAYLRMRSRNAAPFAGYFDGGDWQVVSASPERFLQIDDRFVETRPIKGTCPRTGDAAVDQQLGAQLLSSLKDRAENVMIVDLMRNDLSRVCNDDSIDVAGLCELEQYECVQHLVSRVHGTLRDDVDVVDLLRASFPGGSITGAPKVRAMQIIAELEPTARGPYCGSLGYLSTGGRGDLNILIRTVTCRDGWLQMPVGGGITSRSKPDQEEQETWDKAEGMLRAVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRW5</accession>
    <name>A0A518IRW5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_18010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="200" mass="22295" checksum="9ADD2242FF0A52DF" modified="2019-10-16" version="1">MALESEATTTTAKPSRTRSYLLFGILGLMIIALAYDYKVARPNVEQAYEDLVAFNMQVNADPSDMVTPEMVAEMLGKTPTRTFKDMSDFVEVYSWRGGLFFKSHDLYVAYRVTPLGTLMARTSKFNYDAHREVYEEVYARMGVELPYVEAEDGRYESPVPSSMAAMPMDPQLAVDSGDASVIAVVQDAESIPTVELALQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRX7</accession>
    <name>A0A518IRX7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_18130</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="165" mass="18692" checksum="62BFDC82D763B6DD" modified="2019-10-16" version="1">MARDTHDREDLLAEATGLPVRGVIQMPDGNEVVVGFRDDGSPSWFFAADPVFQFDPSFQLRRIFCDGTRYAVAGGQILRLEQTASGGRLQLTKHPLNSEQTQQMLQRWEDRIRPLQAAMQNKTHRWQGTSVPIAEIEPRVLQWLADCPSPPTIAKVSRLPRRRSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IS35</accession>
    <name>A0A518IS35_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Thymidylate kinase</fullName>
            <ecNumber evidence="4">2.7.4.9</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">tmk_1</name>
        <name evidence="4" type="ORF">Mal33_18840</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.4.9" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008976">
        <property type="term" value="F:polyphosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004798">
        <property type="term" value="F:thymidylate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006797">
        <property type="term" value="P:polyphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016898">
        <property type="entry name" value="Polyphosphate_phosphotransfera"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022300">
        <property type="entry name" value="PPK2-rel_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022488">
        <property type="entry name" value="PPK2-related"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03976">
        <property type="entry name" value="PPK2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028756">
        <property type="entry name" value="PPK2_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03709">
        <property type="entry name" value="PPK2_rel_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PPK2" evidence="3">
        <location>
            <begin position="31"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV55905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="277" mass="32654" checksum="AFFA3F1182795C78" modified="2019-10-16" version="1">MDLYDEYRVKPDGKVQLKVIEPREDKPFKDREEAEQLTAENVEAIRQLQYRMFVEGKQSLLIVLQAPDAAGKDGLIRRVLGKMNPQGCRVHSFKKPTELELAHDFLWRVHPCVPARGQVSIFNRSHYEDVLIVRVHDLVPKSVWKERYDLINSFESLLASAGTRILKFYLHISPEEQLERFKERLDLPEKHWKLNAADYHERDRWDDYREAYQAAFEKCSPKHAPWFVIPADRKWYRNAVVSQIVRKTLEEMDPQLPPVTEDLAEIRRLYGMAEGED</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IS51</accession>
    <name>A0A518IS51_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Type III pantothenate kinase</fullName>
            <ecNumber evidence="6">2.7.1.33</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">PanK-III</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Pantothenic acid kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 7" type="primary">coaX</name>
        <name evidence="7" type="ORF">Mal33_19040</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>(R)-pantothenate + ATP = (R)-4'-phosphopantothenate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16373"/>
            <dbReference type="ChEBI" id="CHEBI:10986"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29032"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.33"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>NH4(+)</name>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
        </cofactor>
        <cofactor evidence="6">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
        <text evidence="6">A monovalent cation. Ammonium or potassium.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 6">Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 1/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the type III pantothenate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.33" evidence="6"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00241">
        <property type="reaction ID" value="UER00352"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004594">
        <property type="term" value="F:pantothenate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01274">
        <property type="entry name" value="Pantothen_kinase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004619">
        <property type="entry name" value="Type_III_PanK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34265">
        <property type="entry name" value="PTHR34265"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03309">
        <property type="entry name" value="Pan_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00671">
        <property type="entry name" value="baf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 6" id="KW-0173">Coenzyme A biosynthesis</keyword>
    <keyword evidence="4 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0630">Potassium</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="111"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="113"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="10"/>
            <end position="17"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>a monovalent cation</name>
            <dbReference type="ChEBI" id="CHEBI:60242"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="137"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV55925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="264" mass="28057" checksum="26228600D59BA5CA" modified="2019-10-16" version="1">MSSRFRVAVDVGNSSIKIAYHPPGMTADASDLRVVRVSLTGADWQAQLADLTSAFPQSDNTVQWLLASVNSVGCDRLSAWIETHRAADRVRVIDRSDVGIETDVRMPQRVGIDRLLAAQSAFRLAGDRSAIVIDAGTTVTVDLVASPGVFRGGAILPGLGLQFRALHEATDKLPRLEPPDDLASLESPGRDTQAAMELGVASGIVGAIDRLVESFQSTCDVSQIFLTGGDAGRLSPAIRSPHRVVVDMPLRGLYGIELADSSSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IS67</accession>
    <name>A0A518IS67_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_19250</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007825">
        <property type="entry name" value="Major_OMP_Legionella"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05150">
        <property type="entry name" value="Legionella_OMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022236631" evidence="1">
        <location>
            <begin position="26"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="382" mass="41082" checksum="C7A82045AC9D9843" modified="2019-10-16" version="1" precursor="true">MGIRNLFKGLALLCSVVLSIHAAQAQEVFQNHDVLPIASAIDDAGEIQQVGFNSMCCDGNCDSCDICQTSPCDDGFADALCTPPWWAHRTGVFGEFLYLRPGNTDTVYAIEQNDATAGAFPTGPIGTTAVDFSAGFRVGAMLANTYTTSLVVAYTHWEGDTQDSIARNGTNVLNSQIIHPSTFTTGGNSLQSSASSSISFDQIDGIYRHKLFCTDTTIFNWSGGFRYGQMEQGLLAQQDISVATGLVTVDTDIDFNGFGLLMGIDAERRSCKTGMLCYTKGVASFLGGEWTGTYRQSNQFGGGVVANQYEDFRITPVLEAGLGVGWQSDSGCIRATAGYTATCWYNALSTRSYVDAVRSGSYVDVDESIAFVGLTSQLEFRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISD8</accession>
    <name>A0A518ISD8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Na(+)-translocating NADH-quinone reductase subunit D</fullName>
            <shortName evidence="14">Na(+)-NQR subunit D</shortName>
            <shortName evidence="14">Na(+)-translocating NQR subunit D</shortName>
            <ecNumber evidence="14">7.2.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">NQR complex subunit D</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">NQR-1 subunit D</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14 15" type="primary">nqrD</name>
        <name evidence="15" type="ORF">Mal33_19700</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>a ubiquinone + H(+) + n Na(+)(in) + NADH = a ubiquinol + n Na(+)(out) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:47748"/>
            <dbReference type="Rhea" id="RHEA-COMP:9565"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="7.2.1.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="14">Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="14">Cell membrane</location>
            <topology evidence="14">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="14">Belongs to the NqrDE/RnfAE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="7.2.1.1" evidence="14"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016655">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006814">
        <property type="term" value="P:sodium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00428">
        <property type="entry name" value="NqrD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011292">
        <property type="entry name" value="NqrD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003667">
        <property type="entry name" value="NqrDE/RnfAE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30586:SF1">
        <property type="entry name" value="PTHR30586:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02508">
        <property type="entry name" value="Rnf-Nqr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006102">
        <property type="entry name" value="NQR_DE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01939">
        <property type="entry name" value="nqrD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="3 14" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10 14" id="KW-0406">Ion transport</keyword>
    <keyword evidence="12 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 14" id="KW-0520">NAD</keyword>
    <keyword evidence="15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 14" id="KW-0915">Sodium</keyword>
    <keyword evidence="13 14" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="6 14" id="KW-1278">Translocase</keyword>
    <keyword evidence="5 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 14" id="KW-0813">Transport</keyword>
    <keyword evidence="11 14" id="KW-0830">Ubiquinone</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="71"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="100"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="179"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="QDV55991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="208" mass="22533" checksum="EA751E2D8C58FE8D" modified="2019-10-16" version="1">MAAIKSKDVLLGPIFHNNPIALQILGICSALAVTNKMSTAFVMCLAVTCVVAASNAAVSSIRTYIPSNIRIIVQMTVIASLVILVDQLLKAYLYDISKQLSVFVGLIITNCIVMGRAEGFAMKNSVGMSFLDGIGNGLGYSMVLMVVAFFRELLGNGSLFGYQVMELTRNGGWYNPNNLMLLPPSAFFLIGFLIWAIRVARPEQVEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISP4</accession>
    <name>A0A518ISP4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Fatty acid desaturase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Mal33_20910</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016717">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03505">
        <property type="entry name" value="Delta9-FADS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015876">
        <property type="entry name" value="Acyl-CoA_DS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11351">
        <property type="entry name" value="PTHR11351"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00075">
        <property type="entry name" value="FACDDSATRASE"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="71"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="193"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="228"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="FA_desaturase" evidence="9">
        <location>
            <begin position="68"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV56112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="345" mass="39671" checksum="5165D6EBFA5EB9C1" modified="2019-10-16" version="1">MSSSPALTDAPSADEALESPDTPSLESELRLEHPSGVDLKDIQWGYSISFLVIHLAALLAFLPWFFSWAGVFAFAAGTVIFGQLGIPICYHRLLTHRSFKTPKWFERTLVTFALCSAQETPARWVAWHRIHHQHSDHREDMHSPLVNFLWAHVNWLVYRNKSTQNFSLYQKYARDILSDRYYMWMEKIPYPMTVFYIGHAILYFAISYAISVGIYGANMQALQLTASLFVWGVLVRTVWVWHITWSVNSLSHMFGYRNYATSDDSRNNWFVSLITGGEGWHNNHHADQSSASVQHRWWELDPNYYVIQLFGICGLATNIVPPMHQRRRGNVATAGADRQSSDAIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISR2</accession>
    <name>A0A518ISR2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">50S ribosomal subunit assembly factor BipA</fullName>
            <ecNumber evidence="2">3.6.5.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">GTP-binding protein BipA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">typA</name>
        <name evidence="2" type="synonym">bipA</name>
        <name evidence="4" type="ORF">Mal33_21110</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>GTP + H2O = GDP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="2">Binds to ribosomes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.-" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03710">
        <property type="entry name" value="BipA_TypA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.250">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00849">
        <property type="entry name" value="BipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035651">
        <property type="entry name" value="BipA_V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042116">
        <property type="entry name" value="TypA/BipA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006298">
        <property type="entry name" value="TypA_GTP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42908:SF8">
        <property type="entry name" value="PTHR42908:SF8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="SSF54980"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01394">
        <property type="entry name" value="TypA_BipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="2" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="Tr-type G" evidence="3">
        <location>
            <begin position="4"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="16"/>
            <end position="21"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="129"/>
            <end position="132"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV56132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="606" mass="67279" checksum="55F6081E77B6FD4A" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISU9</accession>
    <name>A0A518ISU9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phytanoyl-CoA dioxygenase (PhyH)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_21280</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008775">
        <property type="entry name" value="Phytyl_CoA_dOase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05721">
        <property type="entry name" value="PhyH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="294" mass="32834" checksum="0C2750C7484BDFE1" modified="2019-10-16" version="1">MATDYSTFHEPTSDLFERLAAVSDLSPFRLTDEQIAHYHEFGYLAGVRILDDAQIEHLRAELAELVQPDHDGRSLWYEYNSNESSDPDLVLFHALGAWRTRPGFHDMLWNPAFTVAASQLLGGAVRFWHDQLFCKPAHHGGVVAWHQDYSYWKRTQPMAHLTCWIGLDDATADNGCLQYVPGSHRWPLLPITGLAGDMQAIGEVLSEQQMHQLQNPTAIELKAGECAFHHPLMVHGSFANRTDRPRRAAVLNVVRDGVCSADDKPLLDGTDPVPAGQPLAGRYFPLLFDGEGSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISX7</accession>
    <name>A0A518ISX7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">S-adenosylmethionine synthase</fullName>
            <shortName evidence="11">AdoMet synthase</shortName>
            <ecNumber evidence="11">2.5.1.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">MAT</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Methionine adenosyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11 17" type="primary">metK</name>
        <name evidence="17" type="ORF">Mal33_21780</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>ATP + H2O + L-methionine = diphosphate + phosphate + S-adenosyl-L-methionine</text>
            <dbReference type="Rhea" id="RHEA:21080"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="EC" id="2.5.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
        <text evidence="11">Binds 1 potassium ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="11">Binds 2 divalent ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Amino-acid biosynthesis; S-adenosyl-L-methionine biosynthesis; S-adenosyl-L-methionine from L-methionine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Homotetramer; dimer of dimers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11 12">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11 13">Belongs to the AdoMet synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.6" evidence="11"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00315">
        <property type="reaction ID" value="UER00080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004478">
        <property type="term" value="F:methionine adenosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006556">
        <property type="term" value="P:S-adenosylmethionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00086">
        <property type="entry name" value="S_AdoMet_synth1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022631">
        <property type="entry name" value="ADOMET_SYNTHASE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022630">
        <property type="entry name" value="S-AdoMet_synt_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022629">
        <property type="entry name" value="S-AdoMet_synt_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022628">
        <property type="entry name" value="S-AdoMet_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002133">
        <property type="entry name" value="S-AdoMet_synthetase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022636">
        <property type="entry name" value="S-AdoMet_synthetase_sfam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11964">
        <property type="entry name" value="PTHR11964"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02773">
        <property type="entry name" value="S-AdoMet_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02772">
        <property type="entry name" value="S-AdoMet_synt_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00438">
        <property type="entry name" value="S-AdoMet_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000497">
        <property type="entry name" value="MAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55973">
        <property type="entry name" value="SSF55973"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01034">
        <property type="entry name" value="metK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00376">
        <property type="entry name" value="ADOMET_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00377">
        <property type="entry name" value="ADOMET_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 11 12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 11 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 11" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="10 11 12" id="KW-0630">Potassium</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11 17" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="S-AdoMet_synt_N" evidence="14">
        <location>
            <begin position="5"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="domain" description="S-AdoMet_synt_M" evidence="15">
        <location>
            <begin position="118"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="domain" description="S-AdoMet_synt_C" evidence="16">
        <location>
            <begin position="237"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Flexible loop" evidence="11">
        <location>
            <begin position="101"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="17"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="19"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="168"/>
            <end position="170"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="234"/>
            <end position="235"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="243"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="249"/>
            <end position="250"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="266"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <note>ligand shared between two neighboring subunits</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="270"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <note>ligand shared between two neighboring subunits</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="274"/>
        </location>
        <ligand>
            <name>L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU004462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF02773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="QDV56197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="394" mass="42097" checksum="18FB61ABEEDCF7D5" modified="2019-10-16" version="1">MSSGKYLFTSESVSMGHPDKLADQISDGILDALLEQDPHSRVACETMVTTGMACIAGEISSKANVKFSEVVRQVINEVGYTDDQMGINGSTCAVLVSLDAQSPDIAQGVDENSDSGKEIGAGDQGLMFGYACKDTPELMPLPIALSHRIINRITEVRQSGEIGWIRPDNKAQVTVEYEGNKPVRIDTVVVSTQHSPDVDHATIVKEVTEKVIAPCLPAELDKGDIKYHINPTGKFVVGGPHGDCGLTGRKIIVDTYGGWGRHGGGAFSGKDATKVDRSAAYMARHIAKTIVASGVAERCEVQLAYAIGVTEPVSVHVDTQGTGTLSDDQICAAIREFFPLTPGGIIDYLDLRRPIFRPTAAGGHFGRSGDGFTWEKTDRAEEFATVCKNTSVAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IT68</accession>
    <name>A0A518IT68_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_22610</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
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</entry>
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    <name>A0A518IT94_9BACT</name>
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
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                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
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                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
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            <begin position="1"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="68"/>
        </location>
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    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
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    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="191"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
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            <begin position="325"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="445"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="539" mass="58670" checksum="97B229764345B425" modified="2019-10-16" version="1"> </sequence>
</entry>
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                <person name="Pinto D."/>
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                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
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                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
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                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
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                <person name="Mueller R.-W."/>
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                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
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                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <source>
            <dbReference type="EMBL" id="QDV56436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="579" mass="64273" checksum="93687E2C1E9FAAAE" modified="2019-10-16" version="1"> </sequence>
</entry>
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            <authorList>
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                <person name="Boedeker C."/>
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                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
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                <person name="Galperin M.Y."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="1 2">Mal33</strain>
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            <dbReference type="EMBL" id="QDV56523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="265" mass="30463" checksum="40445B77DDD28C37" modified="2019-10-16" version="1">MRPRTVVYRPRKIYTTADVTIATTHFNPVGFRRARETYYEWLPTLGNLASQMVCYEAVLDGDAPEIDGSVRVYGTRAKHFMWQKESLLQIALDRCRTRLFCWMDHDIYYHYDRWLADGVALLSPAVHAVQLFDQFIRYDRNGVDTSFGGTVSGGYCPGGVWVGEVDWLRSIGGFPHHKIIGSGDDELYARMKGYCSHLPKPAHHIWHGDRGNRKYVERHKMLADLGFDDQRDVRVGASGLTEWCTDKPELHAGVRDYFEGRREDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITW0</accession>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
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    <reference evidence="1 2" key="1">
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            <authorList>
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                <person name="Rast P."/>
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                <person name="Jeske O."/>
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                <person name="Kallscheuer N."/>
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                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
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                <person name="Mueller R.-W."/>
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                <person name="Spormann A.M."/>
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                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="1 2">Mal33</strain>
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        <source>
            <dbReference type="EMBL" id="QDV56525.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="514" mass="55361" checksum="BEC117B285EE132B" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
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    <organism evidence="1 2">
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    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
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                <person name="Peeters S.H."/>
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                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
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                <person name="Jeske O."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
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    </reference>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
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    </evidence>
    <sequence length="208" mass="23545" checksum="6A522C82B2D44D0C" modified="2019-10-16" version="1">MTQPKPSSRLSPTLRATEIFRAHGGMMRMADAVRVGISRRTLYQMRDSGQLEQLARGLYRIADLPPLSEPDLVTVAKKVPQGVVYLISALAFHGLTTQIPHEVWIAIPRNSEPPRLAFPPTRAARLSDIAYHLGIERHNCDGVTVKVYSREKTLVDCFCRRNEIELDVAIEAVKAYRTQKQTNFDLVMDYAKKLRAAKTMRPYLEALL</sequence>
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<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
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    <protein>
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            <fullName evidence="2">Uncharacterized protein</fullName>
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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                <person name="Boedeker C."/>
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                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
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                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="213"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="322" mass="35480" checksum="CCB76EE483717930" modified="2019-10-16" version="1">MAVSCSVHGAPRRGLTGSIVGDDKGKLKVKNQLVYRVKVDDPDEAKDCTYFDAITASGLPIVNLSVYSIGNLWIPYSICRSKSAKQDQANIRYWDVTCDFESPKSEGGEQDHQPQEKPESVDDVQPKIEYSSETIEVVAWKDIDGNEILNPVGEHFAEPTMRPVTLVVANLTFYAETFAWSNIADHGSHANAGPWNGKPRYSWLITDVNRSPAKIPIAGDPGDPEAEPPVPPTPDSELEVVQVSYTVKYNPLEHGWRESKILNGTKFRSAVGAAPQIYMDDKNDMPTTGFLDADGLKSETAVYGEWEHIPTLNFSTALKLPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IU51</accession>
    <name>A0A518IU51_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">4-sulfomuconolactone hydrolase</fullName>
            <ecNumber evidence="3">3.1.1.92</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_26090</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.1.92" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102998">
        <property type="term" value="F:4-sulfomuconolactone hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018732">
        <property type="term" value="F:sulfolactone hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032465">
        <property type="entry name" value="ACMSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21240">
        <property type="entry name" value="PTHR21240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04909">
        <property type="entry name" value="Amidohydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="2">
        <location>
            <begin position="27"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="298" mass="33551" checksum="C2591AB7064D48BB" modified="2019-10-16" version="1">MGVIAAGLAVSSSLPVTHAASDASMVVDAHLHCFAGPDDARFPYHQNAPYRPGQAATPEFLLERMDGAGVDRAIVVHPEPYQDDHRYLEHCIEVGKGRLKGTCLFFADQPDSLQRLPQFLRQHEDHIVATRLHAYAPGRLPPWGTPELDRLWSIATDAGVALQIHLEPRYAERLDPYIRRYRETQVIIDHLGRPMQGTLEEHAVVLRWSELPNTVMKLAAIPDQNKYPHRDVKPVVRRLAELWGAERLIYGGGFNAKTTDASYRQYRQQIAQMLPAFSDEDRSKVFGGNAARLFGFDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUB0</accession>
    <name>A0A518IUB0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Metallophos domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_26820</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003993">
        <property type="term" value="F:acid phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008963">
        <property type="entry name" value="Purple_acid_Pase-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49363">
        <property type="entry name" value="SSF49363"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Metallophos" evidence="2">
        <location>
            <begin position="109"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="380" mass="43473" checksum="168E8C35564107B6" modified="2019-10-16" version="1">MRNVLFLLLLFVASDLAVATEIRRIWLTHKSNDPSRIVVNWMSESAGDSVVRFGLTTDYDKTVRVDETTTLHHVEIPLEHRDAVYHYSVSSGDQRSKDATFKAYPSDELRIAIVADWQSKPDLSAIQNDDVHLLMTAGDNIANLFPACGEGTKDCVKPYAALIDAYPDLFRSTPFMPALGNHDRQIRPRGKMPPEEAVYDIDATAFRRFFELPGDEWKWHFDIPQFDLRVIALDFNHISDFGTTWQTCHRFDEASPQFLWYQQQMANPPGFVVTLYNERNASIRNQANKQWHDLFRRGTCCVTGYGYFAERAEVDGFPYYNSSLSGSGAQYRDPHSKFLAGEDSYLLLTLQRSGEMAVKIKSLSGDELDHQSYKQRESTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUL3</accession>
    <name>A0A518IUL3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_27490</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011446">
        <property type="entry name" value="BBP7"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07585">
        <property type="entry name" value="BBP7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021996228" evidence="1">
        <location>
            <begin position="23"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="487" mass="53840" checksum="541FB8D784EE6859" modified="2019-10-16" version="1" precursor="true">MFKKRIIIVATFACLTAIQSFADEPRERVSSSAERIARARWQPIRQPVEDSLEELPSPEPEVISSEMVPFADGEVIVEEGDFYDYDDRYREGAYYGTAGDQGCDGCSNGCNSCRRGRVWNPLFCVGVPSDGWFSAEYLMWWQKGMRLPPLVTTSATTADAGVLERGTTQTLFGGNDDYVTDSLNGMRFRLGFWLDACHRWGIEAEHFGLDTERDSFSASGNGSPILARPFFNMEINGNDSELVSFPGVVNGTVGVNVTSSLEGTAVHLRRLWCCSTGCAELGGCCLPRAYSSRIEGLVGWRRLQLDETLQITENLDAADGSGSFDISDQFNTRTHFNGFNFGVLYQRQRGPWSLDLTGKLAIGSNRQTVDIAGSTVITTDTVQSFDSGILAGASNGGHYERDRFAIVPEVGITAGYNWTRNLRFTLGYTFIYWNNVVRPGDQVDLDLNPSQFPPAIAGAAASNRPGFQFNETDYWVQGWSVGAEYRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUN0</accession>
    <name>A0A518IUN0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Quinone oxidoreductase 1</fullName>
            <ecNumber evidence="2">1.6.5.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">qorA_1</name>
        <name evidence="2" type="ORF">Mal33_27950</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.6.5.5" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003960">
        <property type="term" value="F:NADPH:quinone reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKS_ER" evidence="1">
        <location>
            <begin position="10"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="330" mass="35585" checksum="2804FD5B17F2DC9F" modified="2019-10-16" version="1">MKQIRFEKFGPPSQVAKCVTVDAVGEPSAWEVVVDIEAFPINPADLATLAGRYGSLPKLPAAIGMEAVGRVARCGEAVKDLQVGDRVMVTANNNWAQQRKVPAAAVHKLPAEGDLHQFALMKVNPATALLLLEHDGQLKPKDWLIQNAPLSSVGRCIMQIARVQGLRTINVVRRPESIDHVKRFGGDVAVVDGPQLEQRAREAIKNQPLRLGLDAVAGTSTSRLAACLSEGGTVVNYGMLSGEECCVGGDQLIFRGIRLEGFWLSKRLNRMTLPQRTALYDAISEMIARKTLQFEVDSSFAMDEIAAALARAEEPGRSGKVIVSVAGQSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUR6</accession>
    <name>A0A518IUR6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Polyribonucleotide nucleotidyltransferase</fullName>
            <ecNumber evidence="6">2.7.7.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Polynucleotide phosphorylase</fullName>
            <shortName evidence="6">PNPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 9" type="primary">pnp</name>
        <name evidence="9" type="ORF">Mal33_28260</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>phosphate + RNA(n+1) = a ribonucleoside 5'-diphosphate + RNA(n)</text>
            <dbReference type="Rhea" id="RHEA:22096"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57930"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the polyribonucleotide nucleotidyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.8" evidence="6"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004654">
        <property type="term" value="F:polyribonucleotide nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006402">
        <property type="term" value="P:mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01595">
        <property type="entry name" value="PNPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001247">
        <property type="entry name" value="ExoRNase_PH_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015847">
        <property type="entry name" value="ExoRNase_PH_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036345">
        <property type="entry name" value="ExoRNase_PH_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012162">
        <property type="entry name" value="PNPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015848">
        <property type="entry name" value="PNPase_PH_RNA-bd_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036456">
        <property type="entry name" value="PNPase_PH_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11252">
        <property type="entry name" value="PTHR11252"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03726">
        <property type="entry name" value="PNPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01138">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03725">
        <property type="entry name" value="RNase_PH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005499">
        <property type="entry name" value="PNPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46915">
        <property type="entry name" value="SSF46915"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="SSF54791"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55666">
        <property type="entry name" value="SSF55666"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03591">
        <property type="entry name" value="polynuc_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 6 9" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 6 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="S1 motif" evidence="8">
        <location>
            <begin position="621"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="697"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="706"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="485"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="491"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV56825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="746" mass="81122" checksum="AD9B04005C324BB7" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUV3</accession>
    <name>A0A518IUV3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">D-ribose-binding periplasmic protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rbsB_2</name>
        <name evidence="3" type="ORF">Mal33_28580</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025997">
        <property type="entry name" value="SBP_2_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13407">
        <property type="entry name" value="Peripla_BP_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022241642" evidence="1">
        <location>
            <begin position="20"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="domain" description="Peripla_BP_4" evidence="2">
        <location>
            <begin position="46"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="349" mass="37844" checksum="D8AFE1525CF88455" modified="2019-10-16" version="1" precursor="true">MSKPTFFLLSLFACVSVLGTGCNKSSSDSAGGSDSGQRPSVAYVTNGVASFWVIAEAGVKQGGKDFDADVEVLMPAEGITAQKRMIEDLLTKGTDGIAISPIDPENQTELINKAAKYAKVITHDSDAPDSDRLCYIGVDNYVAGRMCGELVREAMPEGGKLAIFIGRLEQDNARRRRQGVIDAVLGRSEDPTRFDPPDAEIKEGDWHIVGTYTDQFDRAQGKANAEDAISRHPDLAGMVGLFAYNPPLMLEALTQSGHLGKIKVIGFDEAQETLQGIQDGNVYGTVVQNPFEYGRQSVKVLAGLARGENLQSLGIPEDGFLDIPARKIRKDNLDEFWTELKKNMGETPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IV67</accession>
    <name>A0A518IV67_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SGNH_hydro domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_29840</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="domain" description="SGNH_hydro" evidence="2">
        <location>
            <begin position="81"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="334" mass="36969" checksum="DF9433D26B589AC4" modified="2019-10-16" version="1">MNDPNSADGAAEHAHADVGRPRRRKRLRRLLLVGGCLTIVALAYIELTLRRPIGSGPAGPEVAREAFTEPWSSRQFKLLGIGDSVTAGLGAKSAAHSYFQRMLRNPEDEFAGMQGICLSRVLPNIEAENLAVSGSTSPMHWERVQRLPTHAVETFGIVVMTTGGNDLIHSYGRSPAREGAMYGATLDQAEPWIENFAARLDRMLNRIDESFPGGCEIFLANIYDPTDGIGDAPSIFLPPWPDGLAIHARYNAIIQDAAERRSNVTLVPMYEAFLGHGSHCRQFWRETYDSSDPHYWYFSNIEDPNDRGYDAIRRLFLNAIVARRDALPSGGSTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IV78</accession>
    <name>A0A518IV78_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_29910</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037401">
        <property type="entry name" value="SnoaL-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13474">
        <property type="entry name" value="SnoaL_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SnoaL-like" evidence="1">
        <location>
            <begin position="7"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="285" mass="31020" checksum="E7D563839B955D9B" modified="2019-10-16" version="1">MGSEEAVRTTIQDYVVAFNAKDFDAVSKAWSENATHLDHNLAQRTDGRDQIVGDIKTLFEDDAPIKISGTVEHVRMITDSVASVDGQVAVSNGADAPVFNHFSAILKKQGDQWLIDSMEEMPIPTPASAADAISQLEWLVGSWQDADTESPVRATVRRSIGGSFLIRSFQATAADGSVAQSTQIIGWDPIRQQLRSWTFDADGSFGEGMWSRNGDEWLIKATQTLADGRTASGTYILTPESNDAFAVQLVGREIEGELQPSTPSVMVRRVEVSDEPEATVTTTQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVD1</accession>
    <name>A0A518IVD1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Chromosome partition protein Smc</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">smc_2</name>
        <name evidence="3" type="ORF">Mal33_30450</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="48"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="279" mass="31097" checksum="5C31854215A8FB4E" modified="2019-10-16" version="1">MTFLGKIFSALIFVLSMSFLLLAIMVTATHKNWRDAAINPSTGLKQMVEAKERGIKQLQESLTRAEVALAHERAARRTALAALQTEAAELRSNLQNAVSEVQTLEGLKTALTQEVNTQTQELTRLTSENAGLRTQIRKEREDRDQLFYTAARVSDELNATKGVVSEMQERNTQLIAQNTRYKEVLTASDINPEDPIDNAPPKRNGVVLLVSQPSRLVQVSIGYDEGLREGHFLEVTRGGKYLGRLRVRKTEPNQSVAEILPELQSGIMKEGDRVDTSIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVF6</accession>
    <name>A0A518IVF6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_30640</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024524">
        <property type="entry name" value="DUF3800"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12686">
        <property type="entry name" value="DUF3800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="279" mass="32644" checksum="159E9D647BCD5B65" modified="2019-10-16" version="1">MATEFVIYTDESVKDGAYFSNFYGGVLVRSRDLLGVSGRLAACKAEQNLHGELKWTKVTENYLDKYKTVMDVFFDVIAADLAKVRIMFTNNTYVPQGLTSEQRQSEYHRLYYQFIKHGFGLAFSNTEHDGPKRVRLNMDQMPTSREETAKFKAFIEALSRNPEMRRADVNFDRRQIAEVDSKDHDLLQCLDVVLGAITFRLNNQHLIKPEGQRKRGKRTIAKEKLYKHICGRVRLIYTNFNIGESTGTQGDFANRWRHPYRHWKLVPRNHDRDMTRRKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVH7</accession>
    <name>A0A518IVH7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glutamine--tRNA ligase</fullName>
            <ecNumber evidence="8">6.1.1.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Glutaminyl-tRNA synthetase</fullName>
            <shortName evidence="8">GlnRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 12" type="primary">glnS</name>
        <name evidence="12" type="ORF">Mal33_30950</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln)</text>
            <dbReference type="Rhea" id="RHEA:20121"/>
            <dbReference type="Rhea" id="RHEA-COMP:9662"/>
            <dbReference type="Rhea" id="RHEA-COMP:9681"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78521"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.18"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8 9">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.18" evidence="8"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004819">
        <property type="term" value="F:glutamine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006425">
        <property type="term" value="P:glutaminyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006424">
        <property type="term" value="P:glutamyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.240.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00126">
        <property type="entry name" value="Gln_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004514">
        <property type="entry name" value="Gln-tRNA-synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022861">
        <property type="entry name" value="Gln_tRNA_ligase_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000924">
        <property type="entry name" value="Glu/Gln-tRNA-synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020058">
        <property type="entry name" value="Glu/Gln-tRNA-synth_Ib_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020059">
        <property type="entry name" value="Glu/Gln-tRNA-synth_Ib_codon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020056">
        <property type="entry name" value="Rbsml_L25/Gln-tRNA_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011035">
        <property type="entry name" value="Ribosomal_L25/Gln-tRNA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00749">
        <property type="entry name" value="tRNA-synt_1c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03950">
        <property type="entry name" value="tRNA-synt_1c_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00987">
        <property type="entry name" value="TRNASYNTHGLU"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50715">
        <property type="entry name" value="SSF50715"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00440">
        <property type="entry name" value="glnS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 8 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA-synt_1c" evidence="10">
        <location>
            <begin position="32"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA-synt_1c_C" evidence="11">
        <location>
            <begin position="342"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="8">
        <location>
            <begin position="38"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="8">
        <location>
            <begin position="270"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="39"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="45"/>
            <end position="51"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="215"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="234"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="263"/>
            <end position="264"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="271"/>
            <end position="273"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF03950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QDV57094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="561" mass="64141" checksum="649015F31A7B9AE0" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVZ0</accession>
    <name>A0A518IVZ0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_32490</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021756537" evidence="2">
        <location>
            <begin position="24"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="193"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="268"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="379"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="272"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="486" mass="52941" checksum="2875F801232B1093" modified="2019-10-16" version="1" precursor="true">MLRTLCVTILSTTVSILTTAAFAAGPVDEPYTVYVSEAGSYARCGPSGEHYRTDRLIEGEALEVYLETDDGWLGIRPPETSFCWVPADQVEIDADGTTGTILDPDAVAWIGTNLGRARKYRWQVQFQVGETVALIGNTSRETESGEQESWLRIVPPPGEFRWVHDSQIVKSREAMAKLQSERKNMLLAGAVPTAERASDEPADSANDVDAPPAPFDMEAAQREVVEAGGSVIGDAEIAQVSHVEVEPRGSFRSRMSVANDIRVRDMADQDSQVEQVEATDSSWTQAYRSAPPRERTASQNLPASAAFPGDRTGAGSGQLQQMQMELARLMASEASPRQAEALRSDVELLIQTSTDPVDRGRARLLIDRIDQYREIASRRSGQPMGLSTPAPAAPAVAPTTTSSRVASAPRYDREGWLVEVYSSRPEAPPFALTDRDGQTIAYLSPAVGINARRMLNQQVGIVGRLSTRSEGATPHYIGEQVVRLKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVZ9</accession>
    <name>A0A518IVZ9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">L-aspartate oxidase</fullName>
            <ecNumber evidence="4 10">1.4.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">nadB</name>
        <name evidence="13" type="ORF">Mal33_32590</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the oxidation of L-aspartate to iminoaspartate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-aspartate + O2 = H2O2 + iminosuccinate</text>
            <dbReference type="Rhea" id="RHEA:25876"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:77875"/>
            <dbReference type="EC" id="1.4.3.16"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:25877"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Cofactor biosynthesis; NAD(+) biosynthesis; iminoaspartate from L-aspartate (oxidase route): step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.4.3.16" evidence="4 10"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00326"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008734">
        <property type="term" value="F:L-aspartate oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044318">
        <property type="term" value="F:L-aspartate:fumarate oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.700.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003953">
        <property type="entry name" value="FAD-binding_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037099">
        <property type="entry name" value="Fum_R/Succ_DH_flav-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015939">
        <property type="entry name" value="Fum_Rdtase/Succ_DH_flav-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005288">
        <property type="entry name" value="NadB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027477">
        <property type="entry name" value="Succ_DH/fumarate_Rdtase_cat_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42716">
        <property type="entry name" value="PTHR42716"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00890">
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        <property type="match status" value="1"/>
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            <end position="538"/>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00004950"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00008562"/>
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    </evidence>
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        <source>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00029281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00890"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF02910"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="QDV57255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="544" mass="59426" checksum="2FA20D4994B178E8" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IW00</accession>
    <name>A0A518IW00_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_32630</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021870203" evidence="2">
        <location>
            <begin position="21"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="156" mass="16479" checksum="2E97B2986150A52B" modified="2019-10-16" version="1" precursor="true">MRRNTLVMVMLAVIALPAVAEEEKAGKGKAKKGGRNVATQILKQLADVDLTDEQTEKIKAAGKVASVEMAKIRDEAGITGELMKKRAEAAKSLADSDKKGKQRNDAINEAAGLTKPQAEDERSPLEVHPIGCGDADRCAEGKTAQAIAACGAARER</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IW72</accession>
    <name>A0A518IW72_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">pknD_5</name>
        <name evidence="13" type="ORF">Mal33_33440</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="G-protein_beta_WD-40_rep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011045">
        <property type="entry name" value="N2O_reductase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="17"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50974">
        <property type="entry name" value="SSF50974"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="SSF50978"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="13" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="13" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 8" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="256"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="925"/>
            <end position="965"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="1014"/>
            <end position="1046"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="1113"/>
            <end position="1154"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="1155"/>
            <end position="1188"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="1210"/>
            <end position="1244"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="1273"/>
            <end position="1305"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="1354"/>
            <end position="1395"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="1628"/>
            <end position="1661"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="1679"/>
            <end position="1720"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="1734"/>
            <end position="1756"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="1770"/>
            <end position="1805"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="1821"/>
            <end position="1852"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="163"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="678"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="164"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="285"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="QDV57340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1861" mass="203251" checksum="5DB5136E5910A6E8" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IW83</accession>
    <name>A0A518IW83_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative periplasmic serine endoprotease DegP-like</fullName>
            <ecNumber evidence="4">3.4.21.107</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">mucD_7</name>
        <name evidence="4" type="ORF">Mal33_33570</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S1C family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.107" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001940">
        <property type="entry name" value="Peptidase_S1C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00595">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00834">
        <property type="entry name" value="PROTEASES2C"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021890656" evidence="2">
        <location>
            <begin position="30"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="3">
        <location>
            <begin position="273"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV57352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="464" mass="50365" checksum="D98031224D38C7E9" modified="2019-10-16" version="1" precursor="true">MKLRPASMTTLLRSSVICLTTFCTLLAHTAQTAFGSNRDTPVVRVVREASPSVVNIHGHKTVRAGGLPGQGQSFQQVNGMGTGVVIDSRGYVVTNFHVVQDVNDIRVTLADGRPAVARVIAHDLRTDLAVLKIDAREPLPVIRIGTSEDLWVGETVIAIGNAFGYEHTVTQGIVSALHRDVPVNEEQSYTDLIQTSAEINPGNSGGPLLNLDGQMIGINVAVRVGAQGIAFTIPVDQVLDIVSGLIQQKTVNQISHGIRGVTKWKDDESIFEVTSVASGSSAEKEGVGKGDRILQVNGHTVRNHMDFEFSMLELTSRDSIEFEVADSKGDVTLVSLQSRPQTRTTDAISSPVAQRIWTSFGIQGEPVAEATMQDLNRRMETAYGAGLKITSVRPGSQADRQGMQSGDVLLGIRNWQTSNLNDLDYILRSDEFRSGSQSQFFIIRSNKTMIGYLQVAQASRRTTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWA4</accession>
    <name>A0A518IWA4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">5'-nucleotidase SurE</fullName>
            <ecNumber evidence="5">3.1.3.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Nucleoside 5'-monophosphate phosphohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">surE_2</name>
        <name evidence="5" type="synonym">surE</name>
        <name evidence="7" type="ORF">Mal33_33290</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>a ribonucleoside 5'-phosphate + H2O = a ribonucleoside + phosphate</text>
            <dbReference type="Rhea" id="RHEA:12484"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:18254"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58043"/>
            <dbReference type="EC" id="3.1.3.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="5">Binds 1 divalent metal cation per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the SurE nucleotidase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.5" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106411">
        <property type="term" value="F:XMP 5'-nucleosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1210.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00060">
        <property type="entry name" value="SurE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030048">
        <property type="entry name" value="SurE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002828">
        <property type="entry name" value="SurE-like_Pase/nucleotidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036523">
        <property type="entry name" value="SurE-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30457">
        <property type="entry name" value="PTHR30457"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01975">
        <property type="entry name" value="SurE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64167">
        <property type="entry name" value="SSF64167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00087">
        <property type="entry name" value="surE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SurE" evidence="6">
        <location>
            <begin position="3"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="8"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="9"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="95"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV57325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="250" mass="27393" checksum="652C77D373F89758" modified="2019-10-16" version="1">MRIMLTNDDGIFAPGLEAMEREFTPLGDVQTCAPTTEQSGVGHSITYLTPLTYKEVFRENDRLAFAVDGSPADCVKLGISELCEHRPDVVISGINSGLNAGINVLYSGTVAAAIEAAFFGVTSFAVSLEYDPHADYRRAAEIAREIVMKIVARDEAKAGLFNINIPTAATRQPAEVRVVPMGIGHYGSQYIKRQDPNNRDYYWATVDPPPAPTDHNTDLNALAEGFVTVSPLKFDLTRQELLSPMKTWEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWD3</accession>
    <name>A0A518IWD3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ABC-2 family transporter protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_34140</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="23"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="145"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="302"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
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    <sequence length="595" mass="64786" checksum="8E185E70B3A49044" modified="2019-10-16" version="1"> </sequence>
</entry>
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                <person name="Pinto D."/>
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</entry>
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Pinto D."/>
                <person name="Vollmers J."/>
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                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
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</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
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                <person name="Heuer A."/>
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                <person name="Bunk B."/>
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                <person name="Lage O.M."/>
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                <person name="Merkel B.J."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4 5">Mal33</strain>
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        <location>
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            <end position="536"/>
        </location>
    </feature>
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        </location>
    </feature>
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    </evidence>
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        </source>
    </evidence>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
    <sequence length="901" mass="98608" checksum="5C1E770E6F1CB94A" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWT6</accession>
    <name>A0A518IWT6_9BACT</name>
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        <submittedName>
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    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009010">
        <property type="entry name" value="Asp_de-COase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030948">
        <property type="entry name" value="MoCo_extend_TAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12838">
        <property type="entry name" value="Fer4_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50692">
        <property type="entry name" value="SSF50692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04519">
        <property type="entry name" value="MoCo_extend_TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="2">
        <location>
            <begin position="802"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="2">
        <location>
            <begin position="861"/>
            <end position="892"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="2">
        <location>
            <begin position="893"/>
            <end position="922"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1068"/>
            <end position="1115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1068"/>
            <end position="1102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1115" mass="120542" checksum="DEF8B286F6CA33B1" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWY9</accession>
    <name>A0A518IWY9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Carboxy-S-adenosyl-L-methionine synthase</fullName>
            <shortName evidence="1">Cx-SAM synthase</shortName>
            <ecNumber evidence="1">2.1.3.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">cmoA_2</name>
        <name evidence="1" type="synonym">cmoA</name>
        <name evidence="4" type="ORF">Mal33_36150</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>prephenate + S-adenosyl-L-methionine = 3-phenylpyruvate + carboxy-S-adenosyl-L-methionine + H2O</text>
            <dbReference type="Rhea" id="RHEA:51692"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:18005"/>
            <dbReference type="ChEBI" id="CHEBI:29934"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:134278"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.1.3.-" evidence="1"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016743">
        <property type="term" value="F:carboxyl- or carbamoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904047">
        <property type="term" value="F:S-adenosyl-L-methionine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002098">
        <property type="term" value="P:tRNA wobble uridine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01589">
        <property type="entry name" value="Cx_SAM_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005271">
        <property type="entry name" value="CmoA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43861:SF2">
        <property type="entry name" value="PTHR43861:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006325">
        <property type="entry name" value="MeTrfase_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00740">
        <property type="entry name" value="TIGR00740"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_25" evidence="3">
        <location>
            <begin position="59"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="1 2">
        <location>
            <begin position="63"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="1 2">
        <location>
            <begin position="116"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1 2">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1 2">
        <location>
            <position position="131"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR006325-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV57602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="241" mass="26529" checksum="50C80004C1F467E6" modified="2019-10-16" version="1">MSQDDIYALPLENVGDFQFDRRVVDVFPDMISRSVPGYGSILSMIGELAQQYAVADTNIYDLGCSLGAATRIISRRVPNSCTIQAVDSSSAMIARLRELLAAEAIQGCDVALHEADLAAVPVDRASFVVLNFTLQFVPAAERRSVLQTIFDGMLPGGALVLSEKISFDDPQEQLRLTELHHAFKRANGYSELEIAQKRTALEKMMVPETLATHRTRLADVGFATVVPWFQCFNFTSILAVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXC7</accession>
    <name>A0A518IXC7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Carbonic anhydrase</fullName>
            <ecNumber evidence="8">4.2.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">cynT</name>
        <name evidence="8" type="ORF">Mal33_37550</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the beta-class carbonic anhydrase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.1" evidence="8"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004089">
        <property type="term" value="F:carbonate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008271">
        <property type="term" value="F:secondary active sulfate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001765">
        <property type="entry name" value="Carbonic_anhydrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036874">
        <property type="entry name" value="Carbonic_anhydrase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011547">
        <property type="entry name" value="SLC26A/SulP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001902">
        <property type="entry name" value="SLC26A/SulP_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11814">
        <property type="entry name" value="PTHR11814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00484">
        <property type="entry name" value="Pro_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00916">
        <property type="entry name" value="Sulfate_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00947">
        <property type="entry name" value="Pro_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53056">
        <property type="entry name" value="SSF53056"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="17"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="73"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="112"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="165"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="201"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="261"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="300"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="335"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="360"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="397"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="7">
        <location>
            <begin position="434"/>
            <end position="552"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV57741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="758" mass="80159" checksum="4AB443BBC615CAF4" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXD0</accession>
    <name>A0A518IXD0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_37510</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008930">
        <property type="entry name" value="Terpenoid_cyclase/PrenylTrfase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48239">
        <property type="entry name" value="SSF48239"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="371" mass="41133" checksum="584532CCFA9ADDB7" modified="2019-10-16" version="1">MRVREAVRPLGNVVLWILVCCWFDGATAQEVVTFESVPEEREPITADEPMAAEFSAKQAAIYMDRAALTWQKEKNCVTCHTNMPYMFARPALASVQKDSGEVRQFFEEYRTVRWKEKGPNVNNGFWPIVVAAGLTFNDLQTTGHLSPVARDVLDILWTVQREDGGWAWPDCDYAPMEIDDHYGATVAALAIGIAPDGYSQTEQAVAGLEKLRGYFENSPPKSLHHRAMLAWCSVRIDGIVSDEERATTLEQLLGNQLPDGGWSTSGFLTDWKDLLHPDAPPLDTETSDSYGTGLVIVISRELGVPADDPRLQRGIQWLLTNQRESGKWFTRSPVNDAGNLISNTGTALAVLALQSCGKLPGWPLESQQPSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYY0</accession>
    <name>A0A518IYY0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_43110</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="145" mass="14927" checksum="B9E15391473082CE" modified="2019-10-16" version="1">MAESDEDPIVAETAEPPVLAELSVYGAPRRFDLATMLTVTTSYALMFAVLRGCGATDTMVLWGGGFVTLVGVAQAVLFAGTSPRAASILASVASVLATVWFADAASLGGLIAAAIFLGVPLGYLTGALIGGIFLIAHAVRRRIER</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ08</accession>
    <name>A0A518IZ08_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_43350</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039448">
        <property type="entry name" value="Beta_helix"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006626">
        <property type="entry name" value="PbH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13229">
        <property type="entry name" value="Beta_helix"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00710">
        <property type="entry name" value="PbH1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta_helix" evidence="2">
        <location>
            <begin position="392"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="domain" description="Beta_helix" evidence="2">
        <location>
            <begin position="473"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="237"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="240"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="776" mass="85277" checksum="6DAA866491054446" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZE9</accession>
    <name>A0A518IZE9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptide chain release factor 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">prfA_2</name>
        <name evidence="3" type="ORF">Mal33_44330</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the prokaryotic/mitochondrial release factor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003747">
        <property type="term" value="F:translation release factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000352">
        <property type="entry name" value="Pep_chain_release_fac_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045853">
        <property type="entry name" value="Pep_chain_release_fac_I_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00472">
        <property type="entry name" value="RF-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75620">
        <property type="entry name" value="SSF75620"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RF_PROK_I" evidence="2">
        <location>
            <begin position="22"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="172" mass="18883" checksum="B90BAC187C3C0773" modified="2019-10-16" version="1">MSQPSRSSSIPAVALDEQALIQECEVKFTRRGGPGGQHRNKVSSAVVLKHRPTGVTAEASERRSQAENRSVAIARLRVELAIQVREEVEEFAAPLVRQYGGSQFRVAIGNEVYPVILADVLNRTLANEGDVAAAAEFWSTTASQVVRFLRQEPQALSVVNQARQQAGRHRLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZG1</accession>
    <name>A0A518IZG1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Multidrug efflux system subunit MdtA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Mal33_45050</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="6 7">Mal33</strain>
        </source>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="entry name" value="PTHR30367:SF1"/>
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        <property type="match status" value="1"/>
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            <begin position="97"/>
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        <location>
            <begin position="226"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
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        <location>
            <begin position="224"/>
            <end position="289"/>
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    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
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    <evidence type="ECO:0000256" key="2">
        <source>
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        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="QDV58482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="519" mass="55798" checksum="D8FD38EBA116F538" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZG5</accession>
    <name>A0A518IZG5_9BACT</name>
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        <submittedName>
            <fullName evidence="9">MacB-like periplasmic core domain protein</fullName>
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        <name evidence="9" type="ORF">Mal33_45070</name>
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
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                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
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                <person name="Kaster A.-K."/>
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                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="9 10">Mal33</strain>
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    </reference>
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            <topology evidence="1">Multi-pass membrane protein</topology>
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    </comment>
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        <property type="protein sequence ID" value="QDV58484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="UniProtKB-KW"/>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <location>
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            <end position="273"/>
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            <end position="322"/>
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            <end position="371"/>
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            <begin position="16"/>
            <end position="218"/>
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            <end position="366"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV58484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="377" mass="40396" checksum="624BD282AED5368A" modified="2019-10-16" version="1">MLTYVLKTLWRHRARTLLTVTGAAVAMFVFCCVGSVQEGLERLTTGTDANRSLIVFQENRFCPTSSRLPEDYARKILKVDGVRDVMPIQVWTNNCRASLDIVVFNGADPKQIQASRPVKLVAGSWSDFESRRDAAIVGRNVAQRRGLGVGDQFSIGEISVQVAGVFSSTVPSEENLIYTSLQFLQYTRGLDNAGLVTQHEVMLDENAEPDRVAAEIDQVLRAGSVATTTRRKGAFQASTLSDLVDLIGFAHWLGYACVGLVLSLVATTTVMSVQDRIKEYAVLQTIGVRPLRAMRLVLTESTILCLIGGASGTLLAVTALAVGGYSIGAEGATIAFRPSLGLLWSGLVVSLGVGVAAGIAPAIQAATVPIVRALRQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZL5</accession>
    <name>A0A518IZL5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Outer membrane protein OprM</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">oprM_2</name>
        <name evidence="3" type="ORF">Mal33_45520</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
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    </reference>
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        <text evidence="1 2">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
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    <keyword evidence="2" id="KW-1134">Transmembrane beta strand</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="566" mass="62420" checksum="6B40CB9E9518FA15" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZW1</accession>
    <name>A0A518IZW1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative permease YjgP/YjgQ family protein</fullName>
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    <gene>
        <name evidence="7" type="ORF">Mal33_46570</name>
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        <lineage>
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            <taxon>Planctomycetia</taxon>
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    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005495">
        <property type="entry name" value="LptG/LptF_permease"/>
    </dbReference>
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        <property type="entry name" value="PTHR33529"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03739">
        <property type="entry name" value="LptF_LptG"/>
        <property type="match status" value="2"/>
    </dbReference>
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    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="31"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="80"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="123"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="341"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="371"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV58633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="399" mass="43838" checksum="9976A13068ACE8E6" modified="2019-10-16" version="1">MTLLGERPNDAADARVWKTVMTRIDRYLLATYLRTLLICFCSLAGIFVVFHAFNNMEEVAAYARAQGSFVDALSRYYGPYLLAIFDATNAILAVFALVFSVAVLKRNGEMTALLAAGLSHGRILRPMLFAALIVIILAVLNREFLMPNWKDQLGTKAQDLGGQVQRTLKPCYDRMTGIQFHGRGVIIIRKEIVAPALMIRSEMPGMGTQIVGESAVWMPASDEHPAGYLVSQVNQPAEIDTIPSAGFDGKQFVLTRSDHAWLEPGQCFVVSNIEFEHLVSGSQTDRLSSTLQLVRNIQNPSVYSGPDAEVLLHTRIVRPWLDISLVLLGLPLVVTRGDKNLFVVAGWGLGLIAMFFFVKTLFSGLGSSETLISPAMGAWGPIIVFAPMGYSRWKAAGRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J027</accession>
    <name>A0A518J027_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glycosyltransferase family 25 (LPS biosynthesis protein)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_47210</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002654">
        <property type="entry name" value="Glyco_trans_25"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01755">
        <property type="entry name" value="Glyco_transf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="410" mass="46285" checksum="324CD0D4D25EE57A" modified="2019-10-16" version="1">MINLDRDANRLQRFYQALPDEWPFPKPKRFLAIDGSRVPSPPWWVAGDAAWGCFRSHQCVIEQAINDGVESLLVLEDDAFCHEDFGSRFDSFVDELPADWQWVYLGGQHIQRERGLPIQISEHAYRPFNAHRAHAYAIRGLGTMQAIASHLLDRDAWGEKHHVDHRFGELHAEFDGGLYCPDRWLIGQEAGFSNIKQKHLETNFFPDARSFYDLSIDRPVVAVVGSDRRHRLIVVAVLHRLGVSFGTAQPPDSIADAPDSYCAPGFDAVCDHLVEGPRWHLASDKTFRVAHLKLWADRRVKAAKTELPIGATQPKLALLHQDVQAAWPETTFIAVAGDDERVGVEAVHDRQVESAINELASEAEVHRIERVDFHAPEQLVQRLVALVDWEFKPADVATAKQMAISLCRSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0J8</accession>
    <name>A0A518J0J8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RecBCD enzyme subunit RecD</fullName>
            <ecNumber evidence="5">3.1.11.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">recD</name>
        <name evidence="5" type="ORF">Mal33_48830</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.11.5" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008854">
        <property type="term" value="F:exodeoxyribonuclease V activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18808">
        <property type="entry name" value="SF1_C_Upf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045055">
        <property type="entry name" value="DNA2/NAM7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021754">
        <property type="entry name" value="DUF3320"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025103">
        <property type="entry name" value="DUF4011"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887">
        <property type="entry name" value="PTHR10887"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11784">
        <property type="entry name" value="DUF3320"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13195">
        <property type="entry name" value="DUF4011"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_11" evidence="3">
        <location>
            <begin position="691"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="domain" description="AAA_11" evidence="3">
        <location>
            <begin position="1472"/>
            <end position="1521"/>
        </location>
    </feature>
    <feature type="domain" description="AAA_12" evidence="4">
        <location>
            <begin position="1545"/>
            <end position="1743"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="355"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="961"/>
            <end position="988"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV58858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="2148" mass="237569" checksum="947BE68B201EFE95" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J103</accession>
    <name>A0A518J103_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_50420</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="244" mass="27267" checksum="3C3428D698DC1920" modified="2019-10-16" version="1">MSLQVFNYESGSVGSSTNSSGAHLQFVFEDHACPIGSTAYDLLYSLDVNDAHIDIAVPGVTRIPLIYKVRDPDFSELAYRVASDNEIVIVGDKAPVSLPCLDEQKSVKFGFKSEANDRSKADDALKWAGVFGLEHLSDSEMNRAVEIVDELWRGDWEGHCITPIHLYESKADVVRGEYLRPFYQSKWFSCGDFDRGCRYDESDATVRAFATYEQDRNAPLFGSMSPLLVFTFCPICRCISVGNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J159</accession>
    <name>A0A518J159_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Endonuclease/Exonuclease/phosphatase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_51060</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="SSF56219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="3" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021747824" evidence="1">
        <location>
            <begin position="24"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="Endo/exonuclease/phosphatase" evidence="2">
        <location>
            <begin position="32"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV59081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="266" mass="29359" checksum="22520B8612CC3350" modified="2019-10-16" version="1" precursor="true">MKQLIEYLVLAAMALSPVSASYASEPLRLRVLSYNIHHGAGVDSKLDLQRIANVILSVKPDVVALQEVDKNVKRSGDVDQPAELARLTDMNVVFGANIDLQGGHYGNAILSRFPIARNENHMLPNLDGGEQRGVIEVEISLPQSNQSLLLLATHLDHRPDESERLASAAFINKRLAAKPQLPALLAGDMNARPDSETLRRLQAMWTSANQTPMATYPVTQPTIQIDYILHSPAKRWKVIEVKVLDEAVASDHRAIFAVLELQTDLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J179</accession>
    <name>A0A518J179_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Arylsulfatase</fullName>
            <ecNumber evidence="6">3.1.6.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">atsA_35</name>
        <name evidence="6" type="ORF">Mal33_51210</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="PTM">
        <text evidence="3">The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the sulfatase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.6.1" evidence="6"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004065">
        <property type="term" value="F:arylsulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024607">
        <property type="entry name" value="Sulfatase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00523">
        <property type="entry name" value="SULFATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022026496" evidence="4">
        <location>
            <begin position="25"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase" evidence="5">
        <location>
            <begin position="65"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="modified residue" description="3-oxoalanine (Cys)" evidence="3">
        <location>
            <position position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR600917-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV59096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="233" mass="25864" checksum="CF9FB963CEAFF884" modified="2019-10-16" version="1" precursor="true">MRRFCFLQCLLVCGLLFNDSRCFAQQPDRTRLPIPFSPFEGKIGKTYEESKSDWQEPVAAPDGAPNVIVILLNDVGFGQTSTFGGLIPTPNLDKLASEGLRYNRFHTTAICGPSRAALLTGRNHHDTGNGFLMEWATGYPNYSTLIQPTTATIGRVLKGNGYATWWYGKNHNTPDWETTVAGRFDRWPTGMGFDYFYGFNAGETHQYSPVLFENTVPVAVPPTAKSNHAETSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1E7</accession>
    <name>A0A518J1E7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_51970</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022040329" evidence="1">
        <location>
            <begin position="32"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="285" mass="30040" checksum="233B62FF95CD134E" modified="2019-10-16" version="1" precursor="true">MRPQMINAHGKLQASVTAVAVFALLVGSSIATGTASAQSHDGSVQHCSCKLLTGLWAGYRGGKSGGCDACDAGHEPTCGCEQPSCGCEPATCGIEQPACGCEPTCDGGCDGCSGGKSGCGLLSGSSEFLSKFKSKMGKMLRPTPSDCNCCRANTPATKTCGCGKRSHSHSSTMHYRHNEPQPMFPPAAPMIVAPVAPEMHMEGTPHRHYEQQDLPAPKADAVNDPFRDDSVRVRRTPVPAKHASVGHLQPVQHRDEATLRPAVFQQAEAGDRWSAPLHVARLQVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1N9</accession>
    <name>A0A518J1N9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_52850</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="159"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV59257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="765" mass="83757" checksum="E9982579680AB778" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J200</accession>
    <name>A0A518J200_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DNA protection during starvation protein</fullName>
            <ecNumber evidence="4">1.16.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">dps</name>
        <name evidence="4" type="ORF">Mal33_53840</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the Dps family.</text>
    </comment>
    <dbReference type="EC" id="1.16.-.-" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008199">
        <property type="term" value="F:ferric iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016722">
        <property type="term" value="F:oxidoreductase activity, acting on metal ions"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01043">
        <property type="entry name" value="DPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002177">
        <property type="entry name" value="DPS_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023188">
        <property type="entry name" value="DPS_DNA-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008331">
        <property type="entry name" value="Ferritin_DPS_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42932">
        <property type="entry name" value="PTHR42932"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00210">
        <property type="entry name" value="Ferritin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005900">
        <property type="entry name" value="Dps"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01346">
        <property type="entry name" value="HELNAPAPROT"/>
    </dbReference>
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        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DPS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ferritin" evidence="3">
        <location>
            <begin position="45"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV59356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="191" mass="21652" checksum="4F9E0AE34512566A" modified="2019-10-16" version="1">MSTTTEPVNVNPQLSRVETEVRQTEELVDIPIGLPRDDREKTVYQLNQLLADSIMLKDMYKKHHWQVAGPTFYQIHLLLDRHYGQQVDIVDTVAERIQVLGGAARGMPADVAEKSQITHPPRGREVLTDQLTRLLQAHETICNYCRFIAKAIGERGDLGTEDMVVGDVLRINEFQAWFVAEHLAPVPLENS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J237</accession>
    <name>A0A518J237_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cyclic di-GMP phosphodiesterase response regulator RpfG</fullName>
            <ecNumber evidence="2">3.1.4.52</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rpfG_7</name>
        <name evidence="2" type="ORF">Mal33_54350</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.4.52" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071111">
        <property type="term" value="F:cyclic-guanylate-specific phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037522">
        <property type="entry name" value="HD_GYP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006675">
        <property type="entry name" value="HDIG_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00277">
        <property type="entry name" value="HDIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51832">
        <property type="entry name" value="HD_GYP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD-GYP" evidence="1">
        <location>
            <begin position="129"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="318" mass="35801" checksum="F10FB2810E9E04C0" modified="2019-10-16" version="1">MDNLASGFIPISVSMLAPASVVGVELFQAEHKSRRYVLYRASDYPLKQTDLTKLRHRGVHQLFIRKGAQASYQSYLRQMIDNPGDDVPVSARVGALNEVVRDLLDSAFRAGDTDATVSTANYLGQRTADIVCNDQFTRSDLFRVLHHDYATFTHSANVAFYAGMLAAELGFSQEDVAAISSGGLIHDIGKLKIPDKILCKPGRLSEMEFREIKMHPVTGLNQLVHREGLVEGQLMMVYQHHERVCGGGYPVGIGDDDIHPWAKLCAVVDVFEALTSNRPYRTPIPKRRAIELLEHEREGYEQEFLECWKKITSKLWQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J2G4</accession>
    <name>A0A518J2G4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ</fullName>
            <ecNumber evidence="1">4.2.1.59</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">fabZ_3</name>
        <name evidence="1" type="ORF">Mal33_55540</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="4.2.1.59" evidence="1"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008659">
        <property type="term" value="F:(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008693">
        <property type="term" value="F:3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047451">
        <property type="term" value="F:3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004317">
        <property type="term" value="F:3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013114">
        <property type="entry name" value="FabA_FabZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30272">
        <property type="entry name" value="PTHR30272"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07977">
        <property type="entry name" value="FabA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="177" mass="19954" checksum="FDE78035201D6784" modified="2019-10-16" version="1">MRWFWIDRFTYFKSRERAEAIKNISLTEEPVDEYLPAHPVFPNTLIIEGLAQTGGILVSECFDFQQRIVLAKVGKAKFHQPARPGDTLHYTATIDDLQNDGAVITGTSYCKGKLQAEVQMLFAFLDEERFGTGQLFNPANLLTMLRLMRLWEVAQDADGNPLPVSKNLLDDESTAAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ILY2</accession>
    <name>A0A518ILY2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_00250</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004155">
        <property type="entry name" value="PBS_lyase_HEAT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00567">
        <property type="entry name" value="EZ_HEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="169" mass="18200" checksum="4AB8B43AE1D3027D" modified="2019-10-16" version="1">MNPSEIKSMIGRLASPDGVVRERARQALVDSKGEEVMVALIASLDDRRHQVRWEAAKALSEIGDSAASSPLVHAMDDSDSDVAWVAAEGVAGMGEDGLSAVLGGLIRSSRSGEFHRVAHHALKEFSRRGIRRDVVKFVMNALEGAEPKLSGPVATYKAMRQMDVPRLAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ILZ2</accession>
    <name>A0A518ILZ2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">MurG-like transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_00420</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016758">
        <property type="term" value="F:hexosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007235">
        <property type="entry name" value="Glyco_trans_28_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04101">
        <property type="entry name" value="Glyco_tran_28_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_tran_28_C" evidence="2">
        <location>
            <begin position="265"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="180"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="180"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="394" mass="43882" checksum="556870BEF5A7B6A4" modified="2019-10-16" version="1">MIGPTIGFYVHYHGLGHKHRTEAILQHLQIPASVVTSRIDTLDWSGPTLQQVVGIACDIDDVSPRGLPYARDVYSLHYAPLWCEPITRRVAQYTAWLDEARPDVMVVDVSSEISMLTRLASIPQVVMRQHGDRNDPAHQDAYRAAHSLLAPFPKSMEDEQTPGWVQTKTIYLDGFCRQQTAQKNSQDSQNSQDSQNSQDSQDSQDSQIASLAAGESSDAPTIVVMFGRGGNADVHDRLRAAARRVPEYRWRVVGIAAPESAAMPDNLQYVGWVDDPMPYVREADIVVTAAGHNSVMEIGHARRRLIAIAQQRPFDEQIRKAAILDREGLAVGLSQWPDTDQWPELLERAGRLDPRRWDAIFAADGAAQAAAHLQRVATWSRNQRESNQQAVPCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IM71</accession>
    <name>A0A518IM71_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Arylsulfatase</fullName>
            <ecNumber evidence="5">3.1.6.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">atsA_1</name>
        <name evidence="5" type="ORF">Mal33_01350</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="PTM">
        <text evidence="3">The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the sulfatase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.6.1" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004065">
        <property type="term" value="F:arylsulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024607">
        <property type="entry name" value="Sulfatase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00523">
        <property type="entry name" value="SULFATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00149">
        <property type="entry name" value="SULFATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sulfatase" evidence="4">
        <location>
            <begin position="41"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="modified residue" description="3-oxoalanine (Cys)" evidence="3">
        <location>
            <position position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR600917-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV54186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="496" mass="54555" checksum="728559B9F08F1729" modified="2019-10-16" version="1">MAVTMQLLKFVVRDSLALLVLVSICVGFGGFARAADDARLPNVVVFLVDDLGYMDIGANNPDCFYETPNIDALSNTAMRFTDGYAANPVCSPTRYSMMTGKYPSRVDATNFFSGKRSGTFEPAPLNDNMPLEEVTVAEALKTKGYATFFAGKWHLGESEEYYPQNQGFDVNVGGHSKGGPYTGKKYFAPFKNPQMAVESPDGDHLPDRLARDTARFIDAHKAGPFFAYLSFYSVHTPLIGRPDLVAKYKAKAAKINGQEFGDEEQVFGDQPRKVRILQKHAVYAAMVEAMDEAVGKVLAQIEASGVADNTIVIFTSDNGGLSTSEGSPTSNLPLRGGKGWVYEGGIREPWIVRYPGVTEPGSVCNEPICSIDLFPTVAAAAGVEYQHAVDGVDLMPALRGGSLDRQSLYWHYPHYSNQGGIPAGAIREGNFKLIERYEDGRVQLYDLKSDIGERKDLAAEDPERVDQMRRRLHAWYKSVDAKFLQQKKNGPKPWAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMU4</accession>
    <name>A0A518IMU4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_03580</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="100" mass="10848" checksum="5E35E80ADA47269A" modified="2019-10-16" version="1">MRNEIITNAVVNVVDREDRVVVIGCLVVVRRLHLRLKQQLLSYAKAFASCGMPTGMPYPMTRCWRVCTETTSAMLMSGGTQGLSSSGLALMPAMAGSRNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMZ1</accession>
    <name>A0A518IMZ1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FecR protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_04070</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006860">
        <property type="entry name" value="FecR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012373">
        <property type="entry name" value="Ferrdict_sens_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30273">
        <property type="entry name" value="PTHR30273"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04773">
        <property type="entry name" value="FecR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="FecR" evidence="2">
        <location>
            <begin position="165"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="551" mass="60377" checksum="274654DA6B965BB4" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IN06</accession>
    <name>A0A518IN06_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Trehalose utilization</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_04170</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029010">
        <property type="entry name" value="ThuA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06283">
        <property type="entry name" value="ThuA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022193143" evidence="1">
        <location>
            <begin position="25"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="domain" description="ThuA" evidence="2">
        <location>
            <begin position="44"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="310" mass="34569" checksum="1F6F1DBBEF694910" modified="2019-10-16" version="1" precursor="true">MNASLFRRLSALFLIAAVTIVAVADDHRLVLVAGKPSHPPRLHEFNAGVQLLAKCLQDVPGLQTDVVLNGWPKDESILEQADAIVFYMDGGARHEVVQEEGRRLKMLDALAKKGVGLGFMHYGVEILADQASDEFKRWIGGHYENMFSCNPIWEPQFASLPEHPITRGVKPFAIQDEWYFNMRFVADIPGNESREVEDLKFVPILVAAPNDAVRDGPYVYPKGPYPHIQASKGRAEAMLWTVERPDGGRGFGFTGGHFHDNWGNDDFRKVVLNTMLWTAKVEVPAEGVVSAVSEEQLNANLDPKPSRKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IN11</accession>
    <name>A0A518IN11_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dienelactone hydrolase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_04180</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002925">
        <property type="entry name" value="Dienelactn_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01738">
        <property type="entry name" value="DLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DLH" evidence="1">
        <location>
            <begin position="57"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="282" mass="30333" checksum="DC2989B10D823944" modified="2019-10-16" version="1">MCDQDHFEDDLKKYSRRDLGTMAAAGVGAAMLLPRAADAAEVSGSDVTIKTPDGDCDAYFVAPKTGAHAAVLIWPDIFGLRPAFRQMAQRLAESGYSVLVVNPFYRTMKAPTAEKGANTPIPEVRPLAQSLNATTQTTDAKAFIAWLDAQPQVDKSKKIGTTGYCMGGPIVMRTAAAVPNRVGAAATFHGGGLATDSPDSPHRLIPQMKAQFLIAVAENDDQRDPEAKNVLEKSFAAANLPAEIEVYPAGHGWCPPDTRVHNQEQAEKAWKRMLVLFDKALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IN22</accession>
    <name>A0A518IN22_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Probable transcriptional regulatory protein Mal33_04370</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_04370</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the TACO1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.980">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00693">
        <property type="entry name" value="Transcrip_reg_TACO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017856">
        <property type="entry name" value="Integrase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002876">
        <property type="entry name" value="Transcrip_reg_TACO1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026564">
        <property type="entry name" value="Transcrip_reg_TACO1-like_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029072">
        <property type="entry name" value="YebC-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12532">
        <property type="entry name" value="PTHR12532"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01709">
        <property type="entry name" value="Transcrip_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75625">
        <property type="entry name" value="SSF75625"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01033">
        <property type="entry name" value="TIGR01033"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 4" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV54483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="250" mass="27048" checksum="27C4AAB4A1BFB514" modified="2019-10-16" version="1">MAGHSHWAGIKHKKALVDNKRGKLWSRLSKAIIVAAKLGGGDTDTNIRLRKAIDDAKAVSMPKDNIERAVKRGTGELDGGNLEEILYEGYGPGGVAILCDVLTDNRNRTAPEMRVLFERNGGNLGTINSVAYLFDRKGLMLFAAETDEERLTEVALEGGADDIQRSDSGGWEVTCPPESFSDLLAAFEAAELQPELSEVTRLPQTTVEVEGSVAQQAMRLLELLDEHDDVQSVSTNLNITDDALGDEANG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IN65</accession>
    <name>A0A518IN65_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Serine/threonine-protein kinase PknB</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">pknB_4</name>
        <name evidence="2" type="ORF">Mal33_04790</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="11"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="304" mass="34786" checksum="59851063D63001D1" modified="2019-10-16" version="1">MAKARDFFGSYRLTRLIRMGSACQVWEAINETDQKRYALKVLRDELRGDKAEVAGLKYEYDVATQVGPSPRLIKIHDFVTDPKSAYLVLELFSELNMKQALRHGPDSLAYMLNKVVEQSAEGLYFMHTKGWLHCDIKPDNFLVSREGVVKLIDFQISQKKKTGLSKLFGKKSQIQGTRSYMSPEQIRGKNMDERSDIYSYGCVLYEVATGKPPYTGESPNDLLNKHLSAPIPTPLTSNENVSQDFADLIKRMLSKKPEHRPESMWEFLKLVRGMRLFKKQPKKLDVDVFDVASGFKSPEDLLKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INA5</accession>
    <name>A0A518INA5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_05100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="PSCyt2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021843705" evidence="1">
        <location>
            <begin position="33"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="domain" description="PSCyt2" evidence="2">
        <location>
            <begin position="43"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="domain" description="PSD1" evidence="3">
        <location>
            <begin position="308"/>
            <end position="530"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV54555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="559" mass="63473" checksum="931C56565FD8DC28" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IND6</accession>
    <name>A0A518IND6_9BACT</name>
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        <recommendedName>
            <fullName evidence="2">SHD1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_05640</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
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            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="377" mass="42026" checksum="8CC6493D099BC807" modified="2019-10-16" version="1">MKDALSAVFGFLAILFFGSVFGVFFGKSSPTPNATRSDSSFAHDKDSIASSRIEKSTDDGQSEDVQEATSQINKAANQIFLQRTEQFVSQLATWKSEANAIPNTKEELARLKSEVAVHESKQPTPPVHTVREWSTIDEKYKATASLVETDNVKVTLEKVDGKQITVSKAVLIAEDRVYIDKAISLLSAYSAAHSEWQLERDEALVKISETEARILLGEGPAPVPPNRSEVVAELIAAEEKRELAAKFAEEKREMAAMFAEEQRRKREKLAEAKLKSVSRVRRQYAANAYTTILRIFDPEKVLIASVDAQDKKLILTVTNAWHFQPYQIRLQTAQSLWQGWANLSNPDEARISLVDFQGNAVGGSRIWGGSQIWVQDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INE9</accession>
    <name>A0A518INE9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_05650</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="107"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="175" mass="19144" checksum="BCFFBB75CC443C25" modified="2019-10-16" version="1">MKEQLSCPECRHSLSSSRTTLLPDTRKVGCKRCGSHNSLGVWRASNSSLDEFESTPPNPATLAPRDPVADAIAGSSRNAESENPEAKKASSAVKVSKKKLEPKSKNVLTGCLLVGVATVLLCCGCPLMIGDSGGSRYDSVDRDIDKFDRHFPNASEEERRLTRELYEQDSQRRGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INT3</accession>
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        <submittedName>
            <fullName evidence="4">ATP-dependent helicase HepA</fullName>
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            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140658">
        <property type="term" value="F:ATP-dependent chromatin remodeler activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
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        <location>
            <begin position="164"/>
            <end position="326"/>
        </location>
    </feature>
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        <location>
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            <end position="571"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV54747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="599" mass="67717" checksum="058C2C5F3ED876DE" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP37</accession>
    <name>A0A518IP37_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_08030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="62" mass="6768" checksum="EA33BF3CD4C7CDF5" modified="2019-10-16" version="1">MNRVKLISEIVAFHREEDGPTSVEYAIMLAMILGVCILSIQVLSDKTRDSFDQSAAAIDAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP38</accession>
    <name>A0A518IP38_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_08280</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="301" mass="32161" checksum="135D0B7BFF0141DE" modified="2019-10-16" version="1">MIARNPLTLLATTLLMLESVAVGQYAQDAWGSRNAAPAAQANPSSAIRPIDAPSIVDRYRPRGFQSNPQPAAPVNVASAQMGQYPAQQYPVQPSPIQQTAYQVPGDQQQLAQPALPSGQYQVPANPFSNQQNLSAQGQPPQNFQNPQQPIAPSIAPPPTLAQPQYGQTQPTYPQTLYPQPQQQYPLPQQQVSGQPFASMGTSTAISPASTWTAGGAWDCGNVAQTSAVSPQVYVPPNTYTPPVITPDLAPNAYAPNNAGYRPLVALGSPYPNVQVGRGIIGQPTVYVPNQPVRNFFRYLSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP79</accession>
    <name>A0A518IP79_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative major pilin subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_08550</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011453">
        <property type="entry name" value="DUF1559"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07596">
        <property type="entry name" value="SBP_bac_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="331" mass="36099" checksum="B587515BA884974C" modified="2019-10-16" version="1">MIRRRGFTLVELLVVIAIIGILVGLLLPAVQAAREAARRMQCSNNLKQIGLAIHNYHDTYRCIPPGAMPQSTGYQRQTSWLVRLFPFIEQGPAYDQAIFAGTDWTGQHIVDLNWELKNTVVIDSFICPSTDMELKRTETPSSGTQGLGAPTSIQVQLPCYAGIAGTYVNPYDMTSAPSPNYSSYGRGTFNGVMASVGGSGKSSPVRFADITDGTSNTICVGEQSSFYTDSTNTKRDCRAGNHAGGMWTCGPGGDADWWLNITVLRYPVNWNGAATEYCPGYYKHTIMRSNHPGGAQVVLSDGAVRFLPETMDFSNLMRISSRNDGLPVDPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPB5</accession>
    <name>A0A518IPB5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_08960</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="63" mass="6944" checksum="48AC58F28ED1ABE5" modified="2019-10-16" version="1">MESGRVGASTVSRSSARWLGLPSYRIDYFPYHASTFFSGGQQLVGEAQQFSAAIWGQRPNDTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPF3</accession>
    <name>A0A518IPF3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_09370</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="501" mass="55369" checksum="1D912F065750D251" modified="2019-10-16" version="1">MEPVRKNRQQKRRNAFNFGAWIASRQWSKLLPAAPAVITALAIGGACVWTRSRSQALQPRYLKALSTAVESDQTEVAERYASKLVALGAENRPEVQWIQTVIDLRVGRLQNAQEKLIKLAPADTIGYPYAHLFVAKQIVQRNNIDPQTAAKLKHHLIAASSISVERQWTASTLSKIYVAENDLKSATRELEKVVQSKPEVWLLIANLKKQQGDEKGEQQAFAAAADHFSEQLKNDPNDNKNRLALAQATFQTEGFRATETILLEGLKRSPDAAEFRSALASLYVQHADDLRAKSSLQKLELSGVLELIERAIQLVPNHPIALQRLMLFLDESGIAEDKASQVLGDLLASGQANASVHLLVATRAMLTGDDATAKVHMDLGYQKNPNLPVLLNNMAWLVARQDPPQLDAAKSYADRALNLVGNKGEIANRFRDTRGHILVKMERWEEAIADLETAVPQLNDRAKAITLRALAKAYRALDQNEIAAAYEKQASTIGLDSPAID</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPJ2</accession>
    <name>A0A518IPJ2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Tetratricopeptide repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_09600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021921479" evidence="1">
        <location>
            <begin position="27"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="344" mass="37146" checksum="33BE0171162E6FB0" modified="2019-10-16" version="1" precursor="true">MNRILHQAIAVGVFAISLHVSPAAFAQLDRVYPTQGPVVSGSIIQTQPDGVVIQVGGAERKFTLDKIDRVVFDREPGPLTEGRSLVRQEQYEAALTQLGQINMAQISRAEIKADAMFYRAFSQAQVALAGQGNKNAAVKEMYGFVTSVGKNSFHFYDAAKTLGDLALAVGSYDNAVKYYGALARSSDANLQLQSRYLVGWSYLQQKKLDEADKAFAAVTSASVSSPDQLRYQKLALAGQAAIAAGKGDPDKGLESLNKLIEESDAADAELFGRLYNAQGACLAAKSDPEGAVLAYLKTHLLFPSDPDSHAEALAELVQLWPQVGHPERANEARTILQTRYPGRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPK9</accession>
    <name>A0A518IPK9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_10030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="214" mass="23826" checksum="CC0D0869C94ECEEF" modified="2019-10-16" version="1">MLTKGIAAFCVATVLTQLLVVGVLAVRGNLNAASTTKIVGLMNGIDISGDRVADSIRAAKTEPIPSFEEVLDERARDGLEMDLRRRAQENYYNQLQVIQERLRSKESRFDTRKDAFYRKLAELSQGVQEEAMKSLQSTLESLPPATSKDQLIRMLDGGDLNDVVAIVKAMQADKRKKILREFVSPEEADKLQQILNHIGAGEPEKTVIDKARDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPP3</accession>
    <name>A0A518IPP3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">7-cyano-7-deazaguanine synthase</fullName>
            <ecNumber evidence="1">6.3.4.20</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">7-cyano-7-carbaguanine synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">PreQ(0) synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Queuosine biosynthesis protein QueC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1 2" type="primary">queC</name>
        <name evidence="2" type="ORF">Mal33_10350</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>7-carboxy-7-deazaguanine + ATP + NH4(+) = 7-cyano-7-deazaguanine + ADP + H(+) + H2O + phosphate</text>
            <dbReference type="Rhea" id="RHEA:27982"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:45075"/>
            <dbReference type="ChEBI" id="CHEBI:61036"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Purine metabolism; 7-cyano-7-deazaguanine biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the QueC family.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.20" evidence="1"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00391"/>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016879">
        <property type="term" value="F:ligase activity, forming carbon-nitrogen bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008616">
        <property type="term" value="P:queuosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01995">
        <property type="entry name" value="ExsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01633">
        <property type="entry name" value="QueC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018317">
        <property type="entry name" value="QueC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42914">
        <property type="entry name" value="PTHR42914"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06508">
        <property type="entry name" value="QueC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006293">
        <property type="entry name" value="ExsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00364">
        <property type="entry name" value="TIGR00364"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 2" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1" id="KW-0671">Queuosine biosynthesis</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="9"/>
            <end position="19"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="203"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="206"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="209"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="228" mass="24448" checksum="7FC00F8C6A8DC008" modified="2019-10-16" version="1">MTKPAVVLLSGGLDSATCLALARRDGFDPHAISFRYGQRHENELDCARRVADHLGVAKHVVVDINLGQFGGSALTSEIAVPKHDSIDQIDDAIPVTYVPARNTVFLSLALAWAETLDARDIYIGVNALDYSGYPDCRPAFIEQFQRLANLATKVGVESADDAIKIHAPLIDLTKAEIIAQGLKLGVDYGLTLSCYDPADGQPCGHCDACLLRNKGFAENDLTDPSLAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPR0</accession>
    <name>A0A518IPR0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Phthiocerol synthesis polyketide synthase type I PpsC</fullName>
            <ecNumber evidence="9">2.3.1.41</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ppsC</name>
        <name evidence="9" type="ORF">Mal33_10430</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.3.1.41" evidence="9"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05235">
        <property type="entry name" value="SDR_e1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensatn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013120">
        <property type="entry name" value="Far_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032821">
        <property type="entry name" value="PKS_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020807">
        <property type="entry name" value="PKS_dehydratase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042104">
        <property type="entry name" value="PKS_dehydratase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013968">
        <property type="entry name" value="PKS_KR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010080">
        <property type="entry name" value="Thioester_reductase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16197">
        <property type="entry name" value="KAsynt_C_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08659">
        <property type="entry name" value="KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07993">
        <property type="entry name" value="NAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14765">
        <property type="entry name" value="PS-DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00826">
        <property type="entry name" value="PKS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="SSF55048"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01746">
        <property type="entry name" value="Thioester-redct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="B_KETOACYL_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="1 6" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Carrier" evidence="8">
        <location>
            <begin position="2114"/>
            <end position="2191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="442"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1244"/>
            <end position="1273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="443"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1246"/>
            <end position="1273"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="6">
        <location>
            <position position="2151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV55074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="3099" mass="338825" checksum="F751B4C778920BE4" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPS5</accession>
    <name>A0A518IPS5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">pknB_6</name>
        <name evidence="10" type="ORF">Mal33_10530</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="405"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="439"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="470"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="502"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="93"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="11"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV55084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="546" mass="61042" checksum="BD52DAE69A08DDC4" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPT3</accession>
    <name>A0A518IPT3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BPL_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_10670</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019197">
        <property type="entry name" value="Biotin-prot_ligase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015834">
        <property type="entry name" value="UCP016642"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09825">
        <property type="entry name" value="BPL_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016642">
        <property type="entry name" value="UCP016642"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BPL_N" evidence="1">
        <location>
            <begin position="73"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="251" mass="26825" checksum="73AE183A96C5701E" modified="2019-10-16" version="1">MLFCGLVATGIVRAESLPGTDRDTLIRVAIYDHSDGSANGPKNLKRILVRDAGFDAVRVTPEEIQKGILEKFDVLIMPGGSGSKQAEKLGEEGRAVVKSFVRSGGGYVGICAGSYLASSQYTWSLGIVNARVWDRSHWARGTGTVSLGLSPSGRKVLKSKASELDVYYGQGPLLIPHDNPELPGYEVLATYETEIAKKGAPVGAMVGTHAIVRTMFHDGRVLCFSPHPESSGGPNSIMVEGIRWAGSKPRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPU2</accession>
    <name>A0A518IPU2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glutamate--tRNA ligase</fullName>
            <ecNumber evidence="8">6.1.1.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Glutamyl-tRNA synthetase</fullName>
            <shortName evidence="8">GluRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">gltX_1</name>
        <name evidence="8" type="synonym">gltX</name>
        <name evidence="12" type="ORF">Mal33_10770</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + L-glutamate + tRNA(Glu) = AMP + diphosphate + L-glutamyl-tRNA(Glu)</text>
            <dbReference type="Rhea" id="RHEA:23540"/>
            <dbReference type="Rhea" id="RHEA-COMP:9663"/>
            <dbReference type="Rhea" id="RHEA-COMP:9680"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.17"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.17" evidence="8"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004818">
        <property type="term" value="F:glutamate-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006424">
        <property type="term" value="P:glutamyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00808">
        <property type="entry name" value="GluRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00022">
        <property type="entry name" value="Glu_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045462">
        <property type="entry name" value="aa-tRNA-synth_I_cd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020751">
        <property type="entry name" value="aa-tRNA-synth_I_codon-bd_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008925">
        <property type="entry name" value="aa_tRNA-synth_I_cd-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004527">
        <property type="entry name" value="Glu-tRNA-ligase_bac/mito"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000924">
        <property type="entry name" value="Glu/Gln-tRNA-synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020058">
        <property type="entry name" value="Glu/Gln-tRNA-synth_Ib_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033910">
        <property type="entry name" value="GluRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19269">
        <property type="entry name" value="Anticodon_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00749">
        <property type="entry name" value="tRNA-synt_1c"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00987">
        <property type="entry name" value="TRNASYNTHGLU"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48163">
        <property type="entry name" value="SSF48163"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00464">
        <property type="entry name" value="gltX_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 8 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA-synt_1c" evidence="10">
        <location>
            <begin position="2"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA-synt_1c" evidence="10">
        <location>
            <begin position="292"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="domain" description="Anticodon_2" evidence="11">
        <location>
            <begin position="367"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="8">
        <location>
            <begin position="8"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="8">
        <location>
            <begin position="250"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="253"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF19269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QDV55108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="517" mass="58301" checksum="8C2A94B17F0F1F36" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQ04</accession>
    <name>A0A518IQ04_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Arylsulfatase</fullName>
            <ecNumber evidence="11">3.1.6.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Mal33_11220</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="PTM">
        <text evidence="7">The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sulfatase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.6.1" evidence="11"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004065">
        <property type="term" value="F:arylsulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004423">
        <property type="term" value="F:iduronate-2-sulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16030">
        <property type="entry name" value="iduronate-2-sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032506">
        <property type="entry name" value="DUF4976"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035874">
        <property type="entry name" value="IDS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16347">
        <property type="entry name" value="DUF4976"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0106">Calcium</keyword>
    <keyword evidence="5 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021970665" evidence="8">
        <location>
            <begin position="21"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase" evidence="9">
        <location>
            <begin position="26"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4976" evidence="10">
        <location>
            <begin position="386"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="modified residue" description="3-oxoalanine (Cys)" evidence="7">
        <location>
            <position position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR600917-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF16347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QDV55153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="493" mass="55092" checksum="A5BDC5ED8A773E35" modified="2019-10-16" version="1" precursor="true">MKQTVILLCVALATSVATEAADPPKPNVLFIAIDDLNDYISPLDNQAGVKTPNFERLAKRSVTFANAHCAAPVCHASRVATMTGVHPITSGLYNNLFGAHGPRWRDESPALKDAIVLSQHFRNHGYHAAGGGKIFHTLQWTRGDSQNDPDAWDTYRGDPLDPISADWPRPRIIPDARAGISPGRPVGGRNLFGAQPLLVPDAQTGDHMVVDWATEQLNAKHDKPLFLAVGLFRPHIPFEVPKKYFDMHPIDQITLPPTLDNDLDDARVPERQSWHRWVVKNRLWRKMMQGYLASISYTDHQLGRLLDALDASPIKDNTIVVLWSDHGFHIGEKQNWEKFCLWDQTTRVPMFIHAPGVSADGQATRQPATLTDLYPTLCELAGLPIPSQCDGLSLVPQLKDPGLKRDRLSLTSYAFGPEPSHAVSDERYRYIRYADGFEELYDLENDPHEFTNLAASEAHAETKARLAEGLPKVTAPRREIPSDSKYNLRRTNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQB8</accession>
    <name>A0A518IQB8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Formylmethanofuran--tetrahydromethanopterin formyltransferase</fullName>
            <shortName evidence="3">Ftr</shortName>
            <ecNumber evidence="3">2.3.1.101</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">H4MPT formyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">fhcD_1</name>
        <name evidence="3" type="synonym">ffsA</name>
        <name evidence="6" type="ORF">Mal33_12200</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>5,6,7,8-tetrahydromethanopterin + H(+) + N-formylmethanofuran = methanofuran + N(5)-formyl-5,6,7,8-tetrahydromethanopterin</text>
            <dbReference type="Rhea" id="RHEA:18061"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57727"/>
            <dbReference type="ChEBI" id="CHEBI:58018"/>
            <dbReference type="ChEBI" id="CHEBI:58103"/>
            <dbReference type="ChEBI" id="CHEBI:58151"/>
            <dbReference type="EC" id="2.3.1.101"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">One-carbon metabolism; formaldehyde degradation; formate from formaldehyde (H(4)MPT route): step 4/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the FTR family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.101" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00562">
        <property type="reaction ID" value="UER00704"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030270">
        <property type="term" value="F:formylmethanofuran-tetrahydromethanopterin N-formyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046294">
        <property type="term" value="P:formaldehyde catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.520">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00579">
        <property type="entry name" value="FTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014053">
        <property type="entry name" value="ForMFR_H4MPT_ForTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002770">
        <property type="entry name" value="ForMFR_H4MPT_ForTrfase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023447">
        <property type="entry name" value="ForMFR_H4MPT_ForTrfase_fd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022667">
        <property type="entry name" value="ForMFR_H4MPT_ForTrfase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01913">
        <property type="entry name" value="FTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02741">
        <property type="entry name" value="FTR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006414">
        <property type="entry name" value="Ftr_formyl_trnsf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55112">
        <property type="entry name" value="SSF55112"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03119">
        <property type="entry name" value="one_C_fhcD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FTR" evidence="4">
        <location>
            <begin position="6"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="FTR_C" evidence="5">
        <location>
            <begin position="148"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV55250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="298" mass="31642" checksum="07F02A1D9F0C92E3" modified="2019-10-16" version="1">MNALPKIDDTFAEAFPMKATRLIITAIDAELAKIAAQEFCGNASSVIGCDAEAGIERILVADQTPDGRPGVSVLAFAFNRKSLEKAVASRIGQNVLTCPTTACYAGMTSESKEDRIKIGAQLRFFGDGYQFSKKLADRRFWRIPVMDGEFVCEDVTGTVKGIGGGNLLVCGRSQIETLAAVRAAVAAIQSLDDVILPFPAGIVRSGSKVGSKYDKLPASTSHTWCPTLIGQCDSDLEAGERAVYEIVIDGLSEQAVAMAMAVGLRAASLPGVLRISAGNYGGKLGPHHFHLHRLPTID</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQC3</accession>
    <name>A0A518IQC3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Serine protease HhoA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">hhoA_2</name>
        <name evidence="4" type="ORF">Mal33_12650</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001940">
        <property type="entry name" value="Peptidase_S1C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13180">
        <property type="entry name" value="PDZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00834">
        <property type="entry name" value="PROTEASES2C"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022003768" evidence="2">
        <location>
            <begin position="23"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="3">
        <location>
            <begin position="221"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="335"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV55295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="572" mass="61692" checksum="0183DCF4CC95D6F3" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQJ9</accession>
    <name>A0A518IQJ9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Metal-binding domain of cation transport ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_13350</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="277" mass="29095" checksum="2FABD3CD1EEA5FFB" modified="2019-10-16" version="1">MFAQEAAAPHNHAGHDHAGHSHATEATGPHGGTVQSVGDRRIETVIADKGIMFMILGKNDQPIAPPDATGTLKLQVGDSEKEYTYQLKTLKNPAIGVGVDLSKVVDQTLHMNVEITNIGTDPLTFHAMGKLASGKLSDELLISLQATCPVSGQPLGSMGKPPKITIGDKSLFVCCAGCTKKVEVSPDQYLTKYYTAKGEQVREGVFKSTLADAAAIAAQKTCPVMDEPLGGMGVPGKVNVNGKAVYICCPGCAKKLVAEPDKYLADLKAKGITPPAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQL9</accession>
    <name>A0A518IQL9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_13310</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="25"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="163" mass="18749" checksum="5925E4F16B57049F" modified="2019-10-16" version="1">MPFNRINGFYVGAFQMPEKPEMTIDERNEELNEALTARLEQLKAAIEEQETQLNAMRLARDAMHAYRSEGMEDDQRNCIGEINWYVGMIKLKGGWRLCYAKDHEHYSWPGESIDWKPLVDCSIEERIDAVPHIGALREAIVKSKESLVPELEKAIEAVAKLTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQP8</accession>
    <name>A0A518IQP8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">D-tagatose 3-epimerase</fullName>
            <ecNumber evidence="2">5.3.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_13940</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="5.3.1.-" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013022">
        <property type="entry name" value="Xyl_isomerase-like_TIM-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01261">
        <property type="entry name" value="AP_endonuc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="SSF51658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AP_endonuc_2" evidence="1">
        <location>
            <begin position="22"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="273" mass="30155" checksum="4445C4BEBF890399" modified="2019-10-16" version="1">MASFRYGICNETFQDWPLDKALELAKRVGYTGWEVAPFMLADDARSITPQQRSDYRSQVEAAGFEVIGLHWLLAKTEGFYLTTDNAEVRKATTEYFCELAGLCKDLGGKVMVLGSPQQRNVPEGASMEQAYEFAAEVLRGVVPALEENGVRIALEPLGHEEGNFMNTQAQGRQLREMIGSEHVGLHLDVKAMSDETEDIAGLIRENADLMLHFHANDPNRQGPGMGDVDFAPIFEALGAVDYQGWVSVEVFDYAPGVETLVTESMRNMLAAQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQR9</accession>
    <name>A0A518IQR9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF1998 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_13820</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018973">
        <property type="entry name" value="MZB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09369">
        <property type="entry name" value="DUF1998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1998" evidence="2">
        <location>
            <begin position="474"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="317"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="320"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="618" mass="69130" checksum="9BB6E7ED1DE95283" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQX6</accession>
    <name>A0A518IQX6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">FAD_binding_3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_14820</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_3" evidence="1">
        <location>
            <begin position="16"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="405" mass="43533" checksum="5D26976D9645D71E" modified="2019-10-16" version="1">MDSTTDSTTAGRRIWDVVVVGAGVAGATAAIGIARGGASVLLVDRKEFPRDKVCGACLNRDAVSGLEALGVLEPIMRAGALPLSHYDLRSGSRRVTLPLPGGLSISRSAMDAVLVEQAIEAGCEFLSGVTLRLDDDSALPTDAQQEYRQLSDPAGNVTLRGRIVVMATGLASDHLIPQSQMQVAAKPDSRVGFGMSTADFPSDYCEGTIYMAVAKDGYVGASRTEHGQLNIAAAIDRQALRGRTSAEVCGAILQEAGFPVSQRMLAGTWRGTTTLTRRRQNVACERLFVVGDAAGYIEPFTGEGMAWAIRGGRAVAPLVVAAAKHWDAAYIDRWGDLTEDLVITQQYWCHAFARTLRYPKLVRGLLKVVTVVPSLGRFVVRQINRERQHDVFNHWPGNGAGTRNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IR30</accession>
    <name>A0A518IR30_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Polyvinylalcohol dehydrogenase</fullName>
            <ecNumber evidence="3">1.1.2.6</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">pvadh</name>
        <name evidence="3" type="ORF">Mal33_15220</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.2.6" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047059">
        <property type="term" value="F:polyvinyl alcohol dehydrogenase (cytochrome) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025666">
        <property type="entry name" value="PQQ-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018391">
        <property type="entry name" value="PQQ_beta_propeller_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002372">
        <property type="entry name" value="PQQ_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13360">
        <property type="entry name" value="PQQ_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13570">
        <property type="entry name" value="PQQ_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00564">
        <property type="entry name" value="PQQ"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022016404" evidence="1">
        <location>
            <begin position="26"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="domain" description="PQQ_3" evidence="2">
        <location>
            <begin position="69"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13570"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="435" mass="46910" checksum="DBC98F6C9E7781A2" modified="2019-10-16" version="1" precursor="true">MGRLKNFAPICLLISLSLLSQPAAALEPAGLSGLQFPASDWPFWRGPDQNGVASAKQTPPTSWSETENVLWRAEVPGRGHSSPVVIGDRVFITSADHEREVQIVLGLDRATGKQLWETIVHRGGFETRGKKMNLKATLASSTIASDGSRLFINFLNDNAVWTTALDLDGKQLWQTRLTDYQVHQGYGSSPTIYKNLVISSADNKAGGAIVAMDRTNGEIVWRRERPELPNYPSPVVVKAAGRDQLIMTGCDLVTSLDPLTGQTIWEIEGATTECVTTTVTDGKVILTSGGYPDNHISAVAADGSGKIVWENTDREYVPSMLIAKGHVFAILDAGIATCLNVETGEQIWKERLGGTFSSSPVLVGENIYVTSESGKTHIFKASVEGFESVATNSLGSKVFATPAICGGQIFTRVSLTADEKTQEYVYCLADSAATR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IR83</accession>
    <name>A0A518IR83_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">D-arabitol-phosphate dehydrogenase</fullName>
            <ecNumber evidence="4">1.1.1.301</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_15690</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.301" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="PKS_ER" evidence="3">
        <location>
            <begin position="14"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV55592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="342" mass="36687" checksum="242FFE6A69300FC8" modified="2019-10-16" version="1">MKSPAIVNFAPDPGSVEIREFQRPTIGTDDVLVEVAAVGVCGSDLHQWTATHSWPVNYPVVLGHEFAGTIVETGANVASWREGDRIASETAAIIDVDNPMSRRGLYNLDPTRKGFGYGVDGAMTRFVRVPSRCLHRVPDALAFEHAAVTEPCCVAYNAVVKNSRIEPGDRVLVIGPGTIGILCAAVAKLVGADVAVLGLESDTHRFAVAQKYGVTTLTDASEWARQGDGLGVDVVIDAAGVSSTLQLAIELVRPAGWITKVGWGPKPLGFSIDPLVQKNVTLQGSFSHNWPIWERVIGLLTSKQLDVQPIVGGTFGIGQWQQAFERMHHGEIVKSVILPGQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRE2</accession>
    <name>A0A518IRE2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9 10">Multifunctional fusion protein</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="9">Protein translocase subunit SecD</fullName>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="10">Protein-export membrane protein SecF</fullName>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="10" type="primary">secF</name>
        <name evidence="9" type="synonym">secD</name>
        <name evidence="12" type="ORF">Mal33_16370</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the SecD/SecF family. SecD subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the SecD/SecF family. SecF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015450">
        <property type="term" value="F:protein-transporting ATPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0065002">
        <property type="term" value="P:intracellular protein transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043952">
        <property type="term" value="P:protein transport by the Sec complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01463_B">
        <property type="entry name" value="SecD_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01464_B">
        <property type="entry name" value="SecF_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005791">
        <property type="entry name" value="SecD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022813">
        <property type="entry name" value="SecD/SecF_arch_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022645">
        <property type="entry name" value="SecD/SecF_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022646">
        <property type="entry name" value="SecD/SecF_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005665">
        <property type="entry name" value="SecF_bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30081">
        <property type="entry name" value="PTHR30081"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07549">
        <property type="entry name" value="Sec_GG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02355">
        <property type="entry name" value="SecD_SecF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01755">
        <property type="entry name" value="SECFTRNLCASE"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00916">
        <property type="entry name" value="2A0604s01"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00966">
        <property type="entry name" value="3a0501s07"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01129">
        <property type="entry name" value="secD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="56"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="395"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="417"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="443"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="485"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="516"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="577"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="890"/>
            <end position="907"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="914"/>
            <end position="939"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="951"/>
            <end position="970"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1005"/>
            <end position="1023"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1029"/>
            <end position="1057"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="728"/>
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        <source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="QDV55658.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1066" mass="114008" checksum="99C3D15E029AFA16" modified="2019-10-16" version="1"> </sequence>
</entry>
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                <person name="Boedeker C."/>
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                <person name="Vollmers J."/>
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                <person name="Rast P."/>
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                <person name="Bunk B."/>
                <person name="Jeske O."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">Mal33</strain>
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            <begin position="3"/>
            <end position="99"/>
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            <dbReference type="PROSITE" id="PS51502"/>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
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    </evidence>
    <sequence length="102" mass="11692" checksum="3556E9675AC3C0D2" modified="2019-10-16" version="1">MKFAHCVFFTLNDKSDVQCESLIAAGLKYLKPHDGIVSYAMGRREPEMQRPVNDQEFDVCLAIVFADRAAHDAYQVSDPHNEFIAEQKENWKQVRVFDSNVA</sequence>
</entry>
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                <person name="Boedeker C."/>
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                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">Mal33</strain>
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            <dbReference type="SAM" id="MobiDB-lite"/>
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    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55722.1"/>
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            <dbReference type="Proteomes" id="UP000316770"/>
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</entry>
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            <fullName evidence="1">Uncharacterized protein</fullName>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="1 2">Mal33</strain>
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    </dbReference>
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            <dbReference type="EMBL" id="QDV55737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
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    </evidence>
    <sequence length="168" mass="18374" checksum="9B2C86DA89FAD02A" modified="2019-10-16" version="1">MAVDYFLKIDGIKGESEDDKHKDEIELIDFEWAEQQSGSFGQGGGGGAGKVKMENFKFRTYLNAASPALMQSCAEGAHIKDATFTCRKAGGGQKEYYKVTMEDIIVASCHISGGSGEIEEGAWVEGHPVEEVTLNFAKIKWEYHPQKADGSLNSAKTGGYDLKKNKRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IS49</accession>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <location>
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    <evidence type="ECO:0000259" key="1">
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            <dbReference type="Pfam" id="PF04168"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="QDV55904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
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    </evidence>
    <sequence length="859" mass="96013" checksum="B015EBCBB938D465" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IS50</accession>
    <name>A0A518IS50_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
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    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
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                <person name="Meyerdierks A."/>
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                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
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                <person name="Overmann J."/>
                <person name="Amann R."/>
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                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024977">
        <property type="entry name" value="Apc4_WD40_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12894">
        <property type="entry name" value="ANAPC4_WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="8"/>
    </dbReference>
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        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PROTEIN_KINASE_ST"/>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="4" id="KW-0853">WD repeat</keyword>
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        <location>
            <begin position="110"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="1407"/>
            <end position="1448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV55901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1995" mass="219571" checksum="4C5D9807FE88753C" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IS77</accession>
    <name>A0A518IS77_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_19110</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">Mal33</strain>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
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            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="138"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="757" mass="83835" checksum="52CA57CF7FD14409" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISB6</accession>
    <name>A0A518ISB6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Efflux pump membrane transporter BepE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">bepE_2</name>
        <name evidence="3" type="ORF">Mal33_19580</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2090.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82714">
        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
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        <location>
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            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
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            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
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    </feature>
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    </feature>
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    <feature type="transmembrane region" description="Helical" evidence="2">
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
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    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
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            <end position="903"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
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            <end position="932"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
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            <end position="976"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="982"/>
            <end position="1008"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1033"/>
            <end position="1052"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1052" mass="113313" checksum="04336D4B6ADC10C1" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISE3</accession>
    <name>A0A518ISE3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="12 13 14">UvrABC system protein B</fullName>
            <shortName evidence="13">Protein UvrB</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Excinuclease ABC subunit B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13 20" type="primary">uvrB</name>
        <name evidence="20" type="ORF">Mal33_19830</name>
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    <organism evidence="20 21">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetia</taxon>
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            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
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                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10 13">The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11 13 14">Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13 14">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="13">The beta-hairpin motif is involved in DNA binding.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 13 14">Belongs to the UvrB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
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        <property type="term" value="C:cytoplasm"/>
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        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="term" value="C:excinuclease repair complex"/>
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        <property type="project" value="InterPro"/>
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        <property type="term" value="F:ATP binding"/>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
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        <property type="project" value="InterPro"/>
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    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009381">
        <property type="term" value="F:excinuclease ABC activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00204">
        <property type="entry name" value="UvrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001943">
        <property type="entry name" value="UVR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036876">
        <property type="entry name" value="UVR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004807">
        <property type="entry name" value="UvrB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041471">
        <property type="entry name" value="UvrB_inter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024759">
        <property type="entry name" value="UvrB_YAD/RRR_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24029">
        <property type="entry name" value="PTHR24029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02151">
        <property type="entry name" value="UVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12344">
        <property type="entry name" value="UvrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17757">
        <property type="entry name" value="UvrB_inter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46600">
        <property type="entry name" value="SSF46600"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00631">
        <property type="entry name" value="uvrb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50151">
        <property type="entry name" value="UVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="15" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 13 14" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6 13 14" id="KW-0228">DNA excision</keyword>
    <keyword evidence="9 13 14" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8 13 14" id="KW-0267">Excision nuclease</keyword>
    <keyword evidence="4 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13 14" id="KW-0742">SOS response</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="18">
        <location>
            <begin position="32"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="19">
        <location>
            <begin position="436"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="domain" description="UVR" evidence="17">
        <location>
            <begin position="627"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="661"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="258"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Beta-hairpin" evidence="13">
        <location>
            <begin position="98"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="16">
        <location>
            <begin position="682"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="45"/>
            <end position="52"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00026033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00029504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU003587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="QDV56004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="697" mass="78799" checksum="B94F5A197AAEBFCE" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISE7</accession>
    <name>A0A518ISE7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 4">30S ribosomal protein S1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rpsA</name>
        <name evidence="7" type="ORF">Mal33_19790</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the bacterial ribosomal protein bS1 family.</text>
    </comment>
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        <property type="protein sequence ID" value="QDV56000.1"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="term" value="F:RNA binding"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="F:structural constituent of ribosome"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:translation"/>
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        <property type="project" value="InterPro"/>
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        <property type="match status" value="6"/>
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        <property type="entry name" value="NA-bd_OB-fold"/>
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        <property type="entry name" value="Ribosomal_S1"/>
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        <property type="entry name" value="S1_dom"/>
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        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10724:SF7">
        <property type="entry name" value="PTHR10724:SF7"/>
        <property type="match status" value="3"/>
    </dbReference>
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        <property type="entry name" value="S1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002111">
        <property type="entry name" value="RpsA"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00681">
        <property type="entry name" value="RIBOSOMALS1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="6"/>
    </dbReference>
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        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="6"/>
    </dbReference>
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        <property type="entry name" value="S1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="S1 motif" evidence="6">
        <location>
            <begin position="46"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="6">
        <location>
            <begin position="135"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="6">
        <location>
            <begin position="221"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="6">
        <location>
            <begin position="306"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="6">
        <location>
            <begin position="393"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="6">
        <location>
            <begin position="481"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="558"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="558"/>
            <end position="576"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR002111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV56000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="590" mass="66046" checksum="5F2A993D9FEB9C98" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISI4</accession>
    <name>A0A518ISI4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7 10">Phosphoglycerate kinase</fullName>
            <ecNumber evidence="2 7 10">2.7.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 12" type="primary">pgk</name>
        <name evidence="12" type="ORF">Mal33_20310</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7 10">
            <text>(2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:14801"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57604"/>
            <dbReference type="ChEBI" id="CHEBI:58272"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7 11">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7 11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7 10">Belongs to the phosphoglycerate kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.3" evidence="2 7 10"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00185"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004618">
        <property type="term" value="F:phosphoglycerate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00318">
        <property type="entry name" value="Phosphoglycerate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1260">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00145">
        <property type="entry name" value="Phosphoglyc_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001576">
        <property type="entry name" value="Phosphoglycerate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015911">
        <property type="entry name" value="Phosphoglycerate_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015824">
        <property type="entry name" value="Phosphoglycerate_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036043">
        <property type="entry name" value="Phosphoglycerate_kinase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11406">
        <property type="entry name" value="PTHR11406"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00162">
        <property type="entry name" value="PGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000724">
        <property type="entry name" value="Pgk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00477">
        <property type="entry name" value="PHGLYCKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53748">
        <property type="entry name" value="SSF53748"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00111">
        <property type="entry name" value="PGLYCERATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 11" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="5 7 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 10" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="7 8">
        <location>
            <begin position="21"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7 8">
        <location>
            <begin position="60"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7 8">
        <location>
            <position position="37"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 8">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 8">
        <location>
            <position position="153"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="205"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="293"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="324"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <begin position="350"/>
            <end position="353"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000724-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000724-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QDV56052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="394" mass="41207" checksum="A8865D7462E0862F" modified="2019-10-16" version="1">MAKKSIEDIDVAGKRVFMRVDFNVPLDDSLKITDDRRIRMALPSIQSIVNRGGRVILGSHLGRPSGDASDSKYSLAPAAARLSELLGKPVAFATDTVGDDAKAKVAAMGDGDVVLLENLRFNPGEKKGDETFAGQIAAMADIYCNNAFGTCHRTDASMYAVAQKIDGPKVVGNLVAKEIQYLADAISSPERPFVAILGGAKVSDKINVINNLLSVCDKILIGGAMAYTFSLARGGAVGGSLVEKDKVDLARELIEKGGDKLVLPVDTHCGDAFSGDCNKQVVDAGQIPDGWEGFDVGPKTAVMYAEIIKSAKTVVWNGPMGVFEMPPFDAGTRVVAQAVADCPGTTIIGGGDSAAAIEQFGLADKVSHVSTGGGASLEMLEGKAFKAVDILDEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISV6</accession>
    <name>A0A518ISV6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nicotinamide-nucleotide amidohydrolase PncC</fullName>
            <ecNumber evidence="2">3.5.1.42</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">pncC</name>
        <name evidence="2" type="ORF">Mal33_21390</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.5.1.42" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="F:nicotinamide-nucleotide amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036653">
        <property type="entry name" value="CinA-like_C"/>
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        <property type="entry name" value="CinA_C"/>
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    <dbReference type="Pfam" id="PF02464">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142433">
        <property type="entry name" value="SSF142433"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00199">
        <property type="entry name" value="PncC_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CinA" evidence="1">
        <location>
            <begin position="5"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="168" mass="17856" checksum="FF279B7CB1E2D537" modified="2019-10-16" version="1">MTDMNQIAQQVADRLTARQTKVVFAESCTAGLVAASLASIPGISQWLCGSVVTYRESMKIAWLGVSPADLQRFTAVSQTVTDQMADGVLRRTEDADIAAAVTGHLGPNAPPQLDGAVFVSIARRAADGTLAVQSTRHQLKATGRIDRQREAVDCVFSELLNALADADD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISW3</accession>
    <name>A0A518ISW3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RNA recognition motif (RRM, RBD, or RNP domain)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_21560</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="SSF54928"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RRM" evidence="2">
        <location>
            <begin position="4"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="101" mass="10589" checksum="A458EE8E26FB53E4" modified="2019-10-16" version="1">MVGKKLYCGNLVFGASSSDLEQLFGQFGVVESAQVISDRETGRSKGFGFVEMSSSEEAAAAIEGLNEKDFEGRSLVVNEARPREDRGGGGGGYRGGGGGRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IT30</accession>
    <name>A0A518IT30_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_22280</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="261" mass="29779" checksum="54F2B58CD83E788D" modified="2019-10-16" version="1">MRSDGPWTADFGCYGISLENGRLLWASHGSGYWGHIVRLLDFVPGFTNELRDTPRYVEDGKVFCNSGRVLDVKTGKLLRKVAPEDVRSHEKPLSIGAKFAGSGVDRHHPRVRVANDLFLRHAQEAEGWQRGTLEIAAETEMGDSLWRFSIKQLGRHIGSYRLVPPFIYMLVSDEPNSKPHPTKKHYALPNPTRWHFVTLTIETGEVIQDFSLGDEKHSECRIEDVDTEGLLIRRENKKLTYYRRIQPIKAETQPSDNADVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITC6</accession>
    <name>A0A518ITC6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_23260</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="56" mass="6007" checksum="6910631C9C14194B" modified="2019-10-16" version="1">MTELEVGQEGEMGVVKMATSPRFAAKRGSNLGCRIGRLCGFALVRGLAVFMIGGWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITK9</accession>
    <name>A0A518ITK9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_24110</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021516">
        <property type="entry name" value="DUF3179"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11376">
        <property type="entry name" value="DUF3179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="330" mass="36672" checksum="9558979C33F7B467" modified="2019-10-16" version="1">MRIQSGLIRSLLLFIPLAIAGAWSLQRHIDSDQLTVQPVQLRAQGGIGFDLRQATIPVQEIRSGGPPKDGIPSLSNPRMVSAAEATYLRANDRVIGVVSGRETRAYPLAILNYHEIINDRIGELPIAVTYCPLCDSAVVFDRRTPLGELEFGVSGLLYNSNVLMYDRSATESLWSQLKGEGVSGPGARMKLTVLPMELTTWAAWKNRNPMTTVLSPETGHRRNYQGSPYTRYFNQPNLMFPVKPISNSLPLKESVLGVWDDANAIAIPISAFGGKSVQIEKSLGSRKFTVAFDVEDQTIRVIKADAGIQWMNMFWFAWYAFRPETEIASR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITL8</accession>
    <name>A0A518ITL8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_24000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="331" mass="37155" checksum="68A32A305B5A7522" modified="2019-10-16" version="1">MMPTTREWIKHLDLTERVESISRICPDFPELVVERFRSTWDSNERNKNRAANRLEAFRDDSKPALPLPAHLGWEHELFEFAFQEALDEVEARVSRQGKSDLTLSDHLIANAVAPVHLDVGLELSIGQRPDLPNPSDLSDSIHEPVVCEEPGSHFDQWLRLGFYESHLTNESFDKGFDTAYTDIFSSLVSLDDDGDVAKVRIPLTTVDSAEAWSESIDCDMATLVGFRGALTAGFNHCGYSSHRFLLAVNPVLISALGLRAGPWPGPLTLMDNSNEPAVVMRAWKSQRIQADSVGSVFRLNGCELLLRPDILSELEDQNEGKLRYVQRRIEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITV7</accession>
    <name>A0A518ITV7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_25090</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="86" mass="9492" checksum="09CFFE670C3D234C" modified="2019-10-16" version="1">MPRESVDLLLRYYSIEPFGDPWRQTAEIVAAVLNSAGLLDRNQKPIHVDPEDIVPIHPPGWQPKSARRVTLSASESAARSRAAAGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITY7</accession>
    <name>A0A518ITY7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Signal transduction histidine-protein kinase BarA</fullName>
            <ecNumber evidence="9">2.7.13.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">barA_5</name>
        <name evidence="9" type="ORF">Mal33_25460</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.13.3" evidence="9"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029151">
        <property type="entry name" value="Sensor-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103190">
        <property type="entry name" value="SSF103190"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="387"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="8">
        <location>
            <begin position="771"/>
            <end position="891"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="5">
        <location>
            <position position="820"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV56554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="892" mass="98952" checksum="98072DA9F6974273" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUA5</accession>
    <name>A0A518IUA5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">MotA/TolQ/ExbB proton channel family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Mal33_26740</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the exbB/tolQ family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002898">
        <property type="entry name" value="MotA_ExbB_proton_chnl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01618">
        <property type="entry name" value="MotA_ExbB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="44"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="163"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="201"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="MotA_ExbB" evidence="8">
        <location>
            <begin position="131"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV56676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="427" mass="47056" checksum="5EA4C2AD31DBBD31" modified="2019-10-16" version="1">MAGRNNLASNSWSGLASVALGPLVAAIFYSVLYVSPVPFLHRYFMGHPVAYAATVLFFVALVGLIVRHLDTRRQLGIVAGLADSELKPAERTSSDLGEHVTHWLDHLAQLPRSERGCQLVHRLEDLLGRQQRRKTTRFLNDDLRDVSDREADQSHDSLQLVRIIVWAIPMLGFLGTVVGITQTLGGLDFSDGQNAVDNLKAGLYVAFDTTALGLVLSVIAIFLQFPVEKKMNHLMATLDQRSIEILSGGFPEESTADQPLQAIAEMNRAVLASVNQLVETQAELWKKTVDSAHDHWTSVVGNAGDQVQSALTEAIELTLQSHAEHVDKTHQNASQQIEQRWKQWQTALSDNARVLMVQQQTLAQQNELLIGTADRAKELAEVRELLQTNTAGLSAMPEMSDAMRSLARAIDLIVDRVPSQSNRSKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUH7</accession>
    <name>A0A518IUH7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Carboxy-terminal processing protease CtpB</fullName>
            <ecNumber evidence="6">3.4.21.102</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ctpB</name>
        <name evidence="6" type="ORF">Mal33_27430</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the peptidase S41A family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.102" evidence="6"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07560">
        <property type="entry name" value="Peptidase_S41_CPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041489">
        <property type="entry name" value="PDZ_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004447">
        <property type="entry name" value="Peptidase_S41A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005151">
        <property type="entry name" value="Tail-specific_protease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17820">
        <property type="entry name" value="PDZ_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03572">
        <property type="entry name" value="Peptidase_S41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00245">
        <property type="entry name" value="TSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00225">
        <property type="entry name" value="prc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 6" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="PDZ" evidence="5">
        <location>
            <begin position="80"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="408"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="408"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV56745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="477" mass="52034" checksum="FCFF88E3D3A4A682" modified="2019-10-16" version="1">MPVRNTYVIVAVMIVSIACYLKADRMKHAGPVGDAISMIDRYYVDPVDHRALVDGAMQGVVSQLDPYSQFIDPSSYGHFQDALQQRFAGIGIIVEQPDKEDRVRVVTPLFATPAFKAGLRPGDRIMEVDGTTTEGLEIGKVSDLLRGPEGTVVSILVQRGDETLEVEVQRAWIPLESVLGDYRDSENNWVFRLREEPRIAYIRVTTFAEQTVEEVTAALEQLDNDFDSLIIDLRQNQGGLLSAAVDIADMFLEDEVIVTTRGRGGKLEAEFSATSGVLVDDDKPLVIMIDGDSASASEIVAASLKDHRRATVIGERTFGKGTVQNVLPLESGRSALKLTTARYYRPNGENIHRLEGSTDEDAWGVRPSDGFEVKMSDDQRMAAMKRLQSAAYPIMPGGTEVPVVKTATEEEAEQPAEAKADTPDAADTAESPDEAASAADTGKEPPADRHAIEQDPQLMRAVEFLKQTAAKSLKVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUN4</accession>
    <name>A0A518IUN4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tetratricopeptide repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_28010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="68"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="99"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="138"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="170"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="374"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="432" mass="47884" checksum="9C92BFDBBE6E664D" modified="2019-10-16" version="1">MEEAVVFGSETCLLKMNALRNIRDPNRSLFRRWTLSFVVGAAMLGWGWSLVSSRLAGGILLPFAWRDVAAVHIACGLPIAWMLRQWFWRSRFAAKHSVAADLIIGASLLAGFRLLFWSEVDGDAPTEMLVRSNAVTRTAASLVAAFGIVSLASVWGAAGKRGSASDAFPLQGSHWLCGCLVVLLVPAVYELARCQSETKRAFEYVEQSRLGEAAELLRHCLVLRPHLQHEGQEIQLSLQSLAAAIERVRLQTKSSLPREASESQQIRRAVQFAILGQRDRAIALLQPLSDSNSFAFNGGDELLGTLYQDRRDWKQSIAHFHRAADAWSVAPESPTRQSHLAKSIQGVAFGLRKQGEVEQAAAAYRKLLQVAPTAETYFLLAQFYEDIQETARATRHARLAIELSPEQYASAGQQLLAKMQTNHFGCFQLLRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IV49</accession>
    <name>A0A518IV49_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">TPR repeat-containing protein YrrB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">yrrB</name>
        <name evidence="5" type="ORF">Mal33_29590</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001440">
        <property type="entry name" value="TPR_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="1 2" id="KW-0802">TPR repeat</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022244366" evidence="4">
        <location>
            <begin position="32"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="144"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="214"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="248"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="282"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="405"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="408"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV56958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="444" mass="49123" checksum="C666A58225395CB6" modified="2019-10-16" version="1" precursor="true">MSNPKYRLARTLALLATSFFLGSLFASLVMAQESSEPVVARAQMQLQVGEKLVDTIEKGDLLTVLEDRGDTYLIVTYNGHRGVVEKVNAVKIIESADIYTELIQKNPTDGRLFTLRASAWWALKQHQKALDDFDRAIKLGYDAPHAYSSRGMFHAAMGDFDEAIQDYTTALKRDKEKEDFSPLLNRAAVYMTLQKFPDAIADYDEVIQRKPDLASAYQQRAVAHKLSGNLEKAVADFDKAIELSPKNVSALMSRGFVHFQQSDHKRAVEDFAAVIEIEPRAAAAYNNRGFNLQKLGKTTEALADYNKAIELAPDYALAYQNKAWLLITANDPQLGNASVAIQAATKAGELNNFAIISDLAAMAAALAADEQFEEAIGWQEKVLEMAPEDRKPYAEKVLALYQQHEPFDPKLAEGDAEDAATDKTEADAKPEPPTAKKPSESEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IV59</accession>
    <name>A0A518IV59_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cyclic di-GMP phosphodiesterase response regulator RpfG</fullName>
            <ecNumber evidence="2">3.1.4.52</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rpfG_5</name>
        <name evidence="2" type="ORF">Mal33_29740</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.4.52" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071111">
        <property type="term" value="F:cyclic-guanylate-specific phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037522">
        <property type="entry name" value="HD_GYP_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51832">
        <property type="entry name" value="HD_GYP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD-GYP" evidence="1">
        <location>
            <begin position="216"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="428" mass="47409" checksum="338CFE6951627236" modified="2019-10-16" version="1">MADPALASRTRCIDDPHFDPDALIQQVESLEHEVQSLTEQVTHDFEELALLQSLAVSMELRNSTPEPIALMLDFLPKLPLSTMCQAVALVPNMEMFADQQASLSNAATLWSGDPLVEDEVCRKIIDTFGENAQVDPVVINDLAADQIDSRIRDIILVEIRHADRLAGWLIACNHVKPEGCLPGVRDGFTTIEANLILTAGSILATQLHNTRLLRQKEQLFTDVVRAMVNAVEARDDYTCGHSERVALFAQELAKQAGLTVTDCDRIYLTGLLHDVGKIAVPDAVLQKPGLLNAEERSVIETHPDVGWRILYPLVNQLSEVLPGVLFHHERIDGKGYPDGLVGEEIPLDGRILAISDAYDAMTSDRPYRGGMPQEKAEEILRSGAGSQWDADLIGHFFDAMPRMIAIRESYNRREPQARQHGSYMPVEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IV80</accession>
    <name>A0A518IV80_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Arylsulfatase</fullName>
            <ecNumber evidence="7">3.1.6.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">atsA_23</name>
        <name evidence="7" type="ORF">Mal33_29950</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="PTM">
        <text evidence="3">The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the sulfatase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.6.1" evidence="7"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004065">
        <property type="term" value="F:arylsulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032506">
        <property type="entry name" value="DUF4976"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024607">
        <property type="entry name" value="Sulfatase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16347">
        <property type="entry name" value="DUF4976"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00149">
        <property type="entry name" value="SULFATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sulfatase" evidence="5">
        <location>
            <begin position="23"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4976" evidence="6">
        <location>
            <begin position="364"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="158"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="464"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="467"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="modified residue" description="3-oxoalanine (Cys)" evidence="3">
        <location>
            <position position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR600917-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF16347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV56994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="515" mass="57208" checksum="E3E42C025E9F1E2D" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVG4</accession>
    <name>A0A518IVG4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_30730</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021947236" evidence="1">
        <location>
            <begin position="27"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="408" mass="42035" checksum="4CFF3A0930D16219" modified="2019-10-16" version="1" precursor="true">MRSCLPILSLCVGFSAFFTTSPSSFAVGFSATDGQFPAQHWVVLDASGSLTGTVAIGEAEASQAASDTQVILVPLADPEQRVCTRTDAEGNFSIANPQVGVYGLVAYGRQGMASYTIHVLPPISVDSLSPLPQSHLQIALAGADQNLSKRMVRSYGPVVTTQPTKHRYQLASVKSNVADDPTLRRVELLPSGDLEGQLRLPATDLGESQSLDSLNVMLVQNSKVVARTTVDSDGHFRIAELKPGSYGLIASGAAGFASFGFDAVISAARTTQMPSRALFRQASTQIRHGQSVICCPPLVCEICPSPVITVVESCVEHVDSCDCCQEEEFDVEDESVVTEDEFASADAGFGGGYGGGYGGGFGGGGGGSGGFGGLGGIAGLAGLAAVLANDSNSGSGFGLPVVTSPFLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVK7</accession>
    <name>A0A518IVK7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ribosomal protein S6 modification protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rimK_1</name>
        <name evidence="3" type="ORF">Mal33_31220</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013651">
        <property type="entry name" value="ATP-grasp_RimK-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025839">
        <property type="entry name" value="RLAN_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08443">
        <property type="entry name" value="RimK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14401">
        <property type="entry name" value="RLAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="2">
        <location>
            <begin position="287"/>
            <end position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="491" mass="56309" checksum="1A23F5E432C82DF2" modified="2019-10-16" version="1">MAVVIVTEAEQDWIRNIPGVEIVDPHEYLTSQDWNRRRNIKLYNLARSYRYQSLGYYVSLLAEARGHRPFPSVVTIQDLEQRQAIRLVPLELEGLINQCLAPLHSDKFSMSVYFGRNLATRYNRLARELSTMFQAPLLRFEFVRRKKWRLSSAHAIGLEDIPASHQPFVAEQAQRHFNHGSSGKTKRTSYRFDLAILHNPNEAENSPSDEKALQKMVKAAASVGINAELVTIEDAGRLLEFDALFLRETTAVNHYTYRLARRAEREGLVVIDDPKSILQCTNKVYLAELLHKAKIATPETIVAHRGNAQRIAAELGFPCVLKRPDSAFSQGVVKVESLQELTDQLELYFADSELVVAQKYMRTDFDWRIGILDRRPLYACKYHMARGHWQIIKQDSEEKNGKYGKCETMPVEIAPRKAVALAQKAADLIGDGLYGVDIKEADGHFFVIEVNDNPNLDSGIEDKYLRDDLYRRIMESFLRRIERIKSMDLTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVL0</accession>
    <name>A0A518IVL0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_31270</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021912876" evidence="1">
        <location>
            <begin position="21"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="60" mass="6362" checksum="E356090A449E8DA4" modified="2019-10-16" version="1" precursor="true">MNATKDLMRAFLLISAFAMSCLLVGCDNEETLLDVDTPDGGGVEIERSLDTGALDIDVGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVL3</accession>
    <name>A0A518IVL3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">N-formylglutamate amidohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_31240</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007709">
        <property type="entry name" value="N-FG_amidohydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05013">
        <property type="entry name" value="FGase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="231" mass="26855" checksum="602B7576F7186E63" modified="2019-10-16" version="1">MELILTCEHATNHIPSQYEHLFVDARSVLQGHRGWDPGTLALGRMLQRRFSAVLFRTTVSRLLVEVNRSANHRQLFSQYSRSLDQRDKAAVLQRYYWPYRQRIEEWIEDRVAAALPVLHLSLHSFVPELDGQVRTAELGLLYDPRRPAEKAFCDRWRDALKISRPDLRTRRNYPYLGRSDGLTTALRQRFPDPYYIGIEVEVNQALVGPASGWQRLKRDLAATLQATLEKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVU8</accession>
    <name>A0A518IVU8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Site-specific DNA-methyltransferase (adenine-specific)</fullName>
            <ecNumber evidence="2">2.1.1.72</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_32110</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2'-deoxyadenosine in DNA + S-adenosyl-L-methionine = an N(6)-methyl-2'-deoxyadenosine in DNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:15197"/>
            <dbReference type="Rhea" id="RHEA-COMP:12418"/>
            <dbReference type="Rhea" id="RHEA-COMP:12419"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90615"/>
            <dbReference type="ChEBI" id="CHEBI:90616"/>
            <dbReference type="EC" id="2.1.1.72"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.1.1.72" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008170">
        <property type="term" value="F:N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009007">
        <property type="term" value="F:site-specific DNA-methyltransferase (adenine-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022749">
        <property type="entry name" value="D12N6_MeTrfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003356">
        <property type="entry name" value="DNA_methylase_A-5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038333">
        <property type="entry name" value="T1MK-like_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12161">
        <property type="entry name" value="HsdM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02384">
        <property type="entry name" value="N6_Mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HsdM_N" evidence="4">
        <location>
            <begin position="13"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="domain" description="N6_Mtase" evidence="3">
        <location>
            <begin position="64"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF12161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV57207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="146" mass="16290" checksum="2452556232C55E27" modified="2019-10-16" version="1">MSEADGQKFLKNLDKKLWTAADRLRANLDAAVYKHAVLGLIFLKYVSDAFELRQRALEDHLRDAGHDIPGFCKSASLDEIAEHGYVLTPGRYVGAEEVEDDGVPFAEKMEGLTRELATQFHESEKLQSAIRGTGTIFQHRSITVVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IW40</accession>
    <name>A0A518IW40_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase</fullName>
            <ecNumber evidence="8">1.1.1.18</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">iolG_9</name>
        <name evidence="8" type="ORF">Mal33_33070</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.18" evidence="8"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016798">
        <property type="term" value="F:hydrolase activity, acting on glycosyl bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050112">
        <property type="term" value="F:inositol 2-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008152">
        <property type="term" value="P:metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019546">
        <property type="entry name" value="TAT_signal_bac_arc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01409">
        <property type="entry name" value="TAT_signal_seq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0520">NAD</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021707012" evidence="6">
        <location>
            <begin position="41"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="domain" description="GFO_IDH_MocA" evidence="7">
        <location>
            <begin position="47"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV57303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="464" mass="50791" checksum="13E1EBBA2268CBE9" modified="2019-10-16" version="1" precursor="true">MSNQSKTPESQDTRRGFIKATGTVAAAATFAATAAPQVHAAEDNTIQVALVGCGGRGTGAAVNALSVDNGPIKLVAMADVFPKNLERSQKNISNAFKDQEGKVDVPEERQFVDFDAYKKAMDVLRPGDVVILATPPAFRWVHFSYAIEKGLNVFMEKPVTVDGPTTVRIMELNKKAKEKNLKVAVGLMCRHCKARQELFERIQGGEIGEINMLRAYRMAGPTGTAACGPKPEGTSELMYQIANFHGFLWLSGGAVSDFLIHNIDETCWMKNDWPVKVHASGGRHYRGDDVDQNFDSYAMEYTFADGTKMYIGGRTMPGCRSEFASYAHGSKGMAVISTASHTPAKSRIYRGQVADKANLAWEFGQPEPNPYQLEWDDLIAAIREDSEYNEVDRGAMASIVTSMGRMAAHTGQEITLDQMMAHKHEFAPGIDKLTLDSPAPLQAGDDGRYPIPLPGIVKKQEYLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IW41</accession>
    <name>A0A518IW41_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_33150</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021748331" evidence="2">
        <location>
            <begin position="20"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="237"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="241"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="268"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="284" mass="30241" checksum="076141EBEB1EBC80" modified="2019-10-16" version="1" precursor="true">MSHISRLLIIALFTQVAVATTWGQNQLISVEGQFVGVRGQLMQVKGSDAQMYLVLLPKEPNKIQYSGTAAAGWLRPGVFVRFSGMFDDRGVGQEPILEMEAFTPNPRRPPRPDQLADVTPGIYPAEAGGGGGAAALFGGEAKVQPKQVGPSKYRIVGRVAGLGRKGELGVMTGPRQIVQVQLTEETRIKLEMEGAQFAMPGDRVVVEGYANPPTLTNVTANSVQIEAAELLGQVAAKPVRKTAKQRREEAAAKKAEADKPAAEMEADENEAAPAEAPAEADDAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IW62</accession>
    <name>A0A518IW62_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_33330</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="216" mass="24219" checksum="01F33C901F702008" modified="2019-10-16" version="1">MPTATPSPHDRQAAWRQPTNPFATRCVRPAALRFRFDQTGVDLESLVEKLRSQSAVGSVIVGPHGSGKSTLVAHLSGKLQDDFSSVQTKTLRIGDPTRGFIRWAIRQPAGSLLIVDGLEQLDSFRRWALLFVCRLRRIRCLATAHAPLPGFCELHRTAATIDLAKQLASELLSQDKLRIAAAHDFIDQIWDDLDGNLRELWFAMYDWYQAEALASR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWM3</accession>
    <name>A0A518IWM3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Regulator of nucleoside diphosphate kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rnk</name>
        <name evidence="3" type="ORF">Mal33_35010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070063">
        <property type="term" value="F:RNA polymerase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032784">
        <property type="term" value="P:regulation of DNA-templated transcription, elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036953">
        <property type="entry name" value="GreA/GreB_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029462">
        <property type="entry name" value="Rnk_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001437">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023459">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30437">
        <property type="entry name" value="PTHR30437"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01272">
        <property type="entry name" value="GreA_GreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14760">
        <property type="entry name" value="Rnk_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006092">
        <property type="entry name" value="GreA_GreB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Rnk_N" evidence="2">
        <location>
            <begin position="4"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="domain" description="GreA_GreB" evidence="1">
        <location>
            <begin position="54"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="144" mass="15973" checksum="A71262C5D36F5899" modified="2019-10-16" version="1">MAVRKIVVTRQDCQRLESLLASDFTQALCNKENIKNLRGELALARIVEPEKVPPDVVTMGSTVRLLDLDCDELETFTLVYPDEANIAEGKLSVLAPIGTAILGYRVGDMVCWKVPSGESRTRIEEVLFQPERDQPAENPTSLTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWP4</accession>
    <name>A0A518IWP4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cypemycin methyltransferase</fullName>
            <ecNumber evidence="2">2.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">cypM</name>
        <name evidence="2" type="ORF">Mal33_34950</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.1.1.-" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_25" evidence="1">
        <location>
            <begin position="43"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="260" mass="30199" checksum="14CCE01BC85CD8FF" modified="2019-10-16" version="1">MQKSLYDYPQYYDLAFRDETDDEADFIEAAWAKFGDGPLKHLLEPGCGSGRLVVELARRGYDVTGFDLSEPALRYTRSRLRRIDRTAEVLNADMIDFSLPRKFDMAYCTMNTFRHLLTENDARSHLQMVADHLRPGGLYLLGFHLMPPDADEECIERWRGSSGKTSVCFTLRVLDFCRRTRLESLRISMLAKTPRGEIRGRSEFQLRLYKAAQFKTLIAKVPDLELLEVFDFDYDIDEPQRLDNELADAVFVFRRRDSNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWY0</accession>
    <name>A0A518IWY0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Chromosome segregation protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_35860</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1010"/>
            <end position="1030"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="24"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="237"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="303"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="540"/>
            <end position="827"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="852"/>
            <end position="1008"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1030" mass="116448" checksum="89003C31BEE86351" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IX16</accession>
    <name>A0A518IX16_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_36280</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="116" mass="12233" checksum="C4DDD6D63B9E08E1" modified="2019-10-16" version="1">MPDDETAGASSRMQDPGCVTVATAHTASFKRWNGKANGRWGFGLLRIANDLKQTSKPLECVALFATSGKRCGVGLSNGQSTIEGGLWGALPQQVLACRGSFSFQSSMLNACLAFAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IX98</accession>
    <name>A0A518IX98_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Carboxymethylenebutenolidase</fullName>
            <ecNumber evidence="2">3.1.1.45</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">clcD</name>
        <name evidence="2" type="ORF">Mal33_37200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.1.45" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008806">
        <property type="term" value="F:carboxymethylenebutenolidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002925">
        <property type="entry name" value="Dienelactn_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01738">
        <property type="entry name" value="DLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DLH" evidence="1">
        <location>
            <begin position="18"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="246" mass="27042" checksum="F0FBF5F7A7F22187" modified="2019-10-16" version="1">MRIEPTSHVDVQTPSGAMRTHLFRPAAEGKFPAVILYSEIYQMTAPIARTAALIAGHGFVVAVPDVYHEYTELGEAFAYDKAGTDRGNALKTTKELASYDADTRAVIDFLKSDPGCSGRIGAIGICLGGHLAFRAAMNPEVETGVCFYATDIHKGSLGKGMADDSLARIPEIHGELMMIWGRQDPHIPLEGRRIIYDALTAAETRFTWHEFNGEHAFMRDEGHRYDPALAMTLYAMVCQHLASQLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXA1</accession>
    <name>A0A518IXA1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">kinA_2</name>
        <name evidence="9" type="ORF">Mal33_37210</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="162"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="8">
        <location>
            <begin position="185"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="254"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV57708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="457" mass="49893" checksum="BCE07B487F849B2A" modified="2019-10-16" version="1">MTFRSLRIRLLAPLVVCSLLAAVGVAAASYGLAERWATRDLQARWVGIQRTLSQSNFPLNSAVLRLLAELTQSELVTFASDGEVLQQTIDAPAATLVDLQQDLAASDSASETAAVQTLKLPDRRYLAYRFETRNPSLRSDRVGSVLILFDESLLRDARRRAAILPLATGLSTIVALASITLVVTERMVRRIAALQRRVELVAAGDFESSVSDNNGDELGRLGAAVEAMARQLKQLWATVHRQEGQKLLHQIAGGMAHQLRNSLAGARMAIELHADECGQSNDEGVQVAIGQIEQAEDYVRRLLMVASGRQDKDQPADAMTCLQDVRTSLSPIARHLNVNVGWDLESQIATHRVKDGATLSAAVSNLVLNAMQTADDVQVLATIRNQQWLHVSVSDNGPGVAEELIDQLFEPFVTSKPEGLGLGLPVVSRAAEHLDGRVVWMRRGDRTVFDFYARIVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXF9</accession>
    <name>A0A518IXF9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_37880</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="84" mass="9156" checksum="BA714A6577615CF5" modified="2019-10-16" version="1">MTNATNQSPQSTTQFALDRLAKAIATAKRLGFVVRSEWLGGSATGWCELGGKRILFVDLSLSVHEQLEQVEAAIEALQAERNKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXG3</accession>
    <name>A0A518IXG3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 13">Membrane protein insertase YidC</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12 13">Foldase YidC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11 13">Membrane integrase YidC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Membrane protein YidC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13 16" type="primary">yidC</name>
        <name evidence="16" type="ORF">Mal33_37960</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Cell membrane</location>
            <topology evidence="13">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.</text>
    </comment>
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        <property type="protein sequence ID" value="QDV57782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032977">
        <property type="term" value="F:membrane insertase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01810">
        <property type="entry name" value="YidC_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019998">
        <property type="entry name" value="Membr_insert_YidC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028055">
        <property type="entry name" value="Membr_insert_YidC/Oxa1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041489">
        <property type="entry name" value="PDZ_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001708">
        <property type="entry name" value="YidC/ALB3/OXA1/COX18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038210">
        <property type="entry name" value="YidC_periplasmic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038221">
        <property type="entry name" value="YidC_periplasmic_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12428">
        <property type="entry name" value="PTHR12428"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02096">
        <property type="entry name" value="60KD_IMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17820">
        <property type="entry name" value="PDZ_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14849">
        <property type="entry name" value="YidC_periplas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03592">
        <property type="entry name" value="yidC_oxa1_cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 13" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10 13" id="KW-0143">Chaperone</keyword>
    <keyword evidence="9 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 13" id="KW-0653">Protein transport</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 13" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="551"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="681"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="720"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="15">
        <location>
            <begin position="136"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="26"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="775"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="43"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="60"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00033245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00033342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="QDV57782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="804" mass="88665" checksum="03F65359546B5827" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXJ7</accession>
    <name>A0A518IXJ7_9BACT</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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    </gene>
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        <lineage>
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            <taxon>Planctomycetia</taxon>
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    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
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    </dbReference>
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        <property type="entry name" value="DUF3365"/>
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    </dbReference>
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        <location>
            <begin position="1"/>
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        </location>
    </feature>
    <feature type="chain" id="PRO_5022028789" evidence="1">
        <location>
            <begin position="32"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="180" mass="19336" checksum="D443F2BE68D3B11A" modified="2019-10-16" version="1" precursor="true">MKRISLKVRLATLAVAAIGGFQVITSPNAPAQAPAPNAKAVQRSRQTVQTLDNIFKQTIVLVTDKYVNDDDDFAAGSAAVLLFKNISEGSDNTIRLIDATGDPYDSDNVAKDDFEKSGIKKLKAGAKTVDQVVVRDGKHYLRALTPVPVVMQKCVMCHAHYADAKPGEPIGAISYTVPIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXK1</accession>
    <name>A0A518IXK1_9BACT</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_38230</name>
    </gene>
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        <lineage>
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            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="entry name" value="DUF309"/>
    </dbReference>
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        <property type="entry name" value="TTHA0068_sf"/>
    </dbReference>
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        <property type="entry name" value="DUF309"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF140663"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="202" mass="21808" checksum="D797187F257731C3" modified="2019-10-16" version="1">MNKSEPSALPLLPARLTSLPFPCYAFVPGMHPHPISDPRGHSWGSSDDSLDPADAAVCHNVYCWAVDLFNHGYVWEAHEAWESLWIAAGRVGPAATFLKGLIKLAAAGVKARQGKLVGVRRHARRAAELFQQAADDRSFSSELQFGLSCQLMRQNSMNVLDAAASTIDPTPQPVLRVLPVVLHPIFPGDAAESPPPTANDQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IY49</accession>
    <name>A0A518IY49_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Long-chain-fatty-acid--CoA ligase</fullName>
            <ecNumber evidence="3">6.2.1.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">lcfB_2</name>
        <name evidence="3" type="ORF">Mal33_40290</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="1">
        <location>
            <begin position="25"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding_C" evidence="2">
        <location>
            <begin position="466"/>
            <end position="541"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="566" mass="62829" checksum="6A09BBC9AFD043A2" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IY99</accession>
    <name>A0A518IY99_9BACT</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_40830</name>
    </gene>
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        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
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            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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            <begin position="1"/>
            <end position="22"/>
        </location>
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    <feature type="chain" id="PRO_5021820865" evidence="1">
        <location>
            <begin position="23"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="119" mass="12451" checksum="7464274657C64441" modified="2019-10-16" version="1" precursor="true">MRMIAVLGLVGISAALSLSAVAEDAEPKHSIKECMKTCFKGPLIKKVAGGEATDEEKAKLHEMMVAMAKATPKKGDAESWKTKTEALVKASKAAVEGDANAAGMLKKAANCKACHSVHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYF6</accession>
    <name>A0A518IYF6_9BACT</name>
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        <submittedName>
            <fullName evidence="2">Methylthioribulose-1-phosphate dehydratase</fullName>
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        </submittedName>
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        <name evidence="2" type="primary">mtnB</name>
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        <name type="scientific">Rosistilla oblonga</name>
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        <lineage>
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            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
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                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
    <dbReference type="Pfam" id="PF00596">
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53639">
        <property type="entry name" value="SSF53639"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldolase_II" evidence="1">
        <location>
            <begin position="9"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="290" mass="32137" checksum="FF0E016C313346A0" modified="2019-10-16" version="1">MQNIHKIKQDICEIGKRIYAKGFAAANDGNITVRVSENEVLCTPTMHCKGYLKPEDISVVDMTGKQLSGNKKRSSEALLHLEIYKQRPELKSVVHCHPPHATAFAVAREPIPQCVLPEVEVFLGDVPITKYETPGGQAFADTVIPYIHKSNVIILANHGTVSFGENVERAYWWTEILDAYCRILLLSRQLGHVQYLSGDKSRELLELKDKWGFTDPRLTKEFENCDICANDVFRDSWEANGVSRRAFDAPPAAGSMTGGAAPAAAAGKNVDEEQLVKLITAEVMRQMGKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYM6</accession>
    <name>A0A518IYM6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PDZ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_42010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
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            <taxon>Rosistilla</taxon>
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    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="LRR_dom_sf"/>
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        <property type="entry name" value="PDZ"/>
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        <property type="entry name" value="PDZ_sf"/>
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        <property type="entry name" value="PDZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <location>
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            <end position="23"/>
        </location>
    </feature>
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        <location>
            <begin position="24"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="2">
        <location>
            <begin position="307"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
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    </evidence>
    <evidence type="ECO:0000259" key="2">
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
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        </source>
    </evidence>
    <sequence length="418" mass="46014" checksum="77A01C285EB909E2" modified="2019-10-16" version="1" precursor="true">MSLKLYTCSTLLFSIVAAVSVCRGDEADSATVDPVESSQPAADKDAAEQMQRWVSQLSSPQYRLRELATTRLRLAGLAAVPALEAGLQDGDLETTSQILSVLRQLSIQFDPQHQERDLAWESLQQVATAGASSAATRAQLAMDEVRDDRKRRAVEVLTAAGVFIGFGEFHLASSVRNGYHMRIPKDWQGNVAAFSWLKWLHGVETVILSGDKITADVVRQVASVPDLKNLDIRDTTVDVEDLQGLTDLKRLDLFQLVNVPAGDELIDTLAQLPLRRELILFGTDISLEGSERLKTLFPNLNIQCRGGFLGVRCSPLNPNCEVGTVEPNTAAAEAGVQSGDVIIKFGQYDVKSFADLQSAIAKHTAAEKSIPMQINRIVEEQVEVELPQEEGEPTPKLIRTIRRQKTFTLTVKLKRQFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYN1</accession>
    <name>A0A518IYN1_9BACT</name>
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        <submittedName>
            <fullName evidence="3">Outer membrane biogenesis protein BamB</fullName>
        </submittedName>
    </protein>
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        <name evidence="3" type="ORF">Mal33_42130</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018391">
        <property type="entry name" value="PQQ_beta_propeller_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002372">
        <property type="entry name" value="PQQ_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13360">
        <property type="entry name" value="PQQ_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00564">
        <property type="entry name" value="PQQ"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022059983" evidence="2">
        <location>
            <begin position="21"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="428" mass="46533" checksum="8194B8FCE93EEEBB" modified="2019-10-16" version="1" precursor="true">MKLLLPTGLALLLMLPLHQADGEQWPGWRGPRGDGSSQETAPPTDWDGATGKNILWTKDLPGTGHGSPIVWNDKLFLVTCIEDQHDRQLLCISTATGETLWKSTVFNAPLETKHSLNSFASTTPATDGEQVVAVFLEVDGSKAPAKNVGKARNLTPGKIVVAAYDLAGKQRWLARPGVFSSVHGFCSNPVLFGDLVIINGDHDGDSFLVALDRNTGKTVWKVPRRHQTRSYATPLIREVDGADQLVLPGSMAVTSFNPRDGSTLWTVEGPTEQFVASPVYDGKHFFVTAGYPTHHVVAIRPDGREDVSDSHVTWHSTDVRSYVPSPVLAGQFLIVADDRGTANCYDTATGERFWNVRLGRKFSASPVMAAGKVFLLAEDGTMHIVQPGKEFQQIAEPQLGERAFASPAIADGRIYIRGEQRLFAIGAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYR9</accession>
    <name>A0A518IYR9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_42410</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021974738" evidence="2">
        <location>
            <begin position="22"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="325"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="336"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="389" mass="39331" checksum="EEFCAFD257850743" modified="2019-10-16" version="1" precursor="true">MTNSRLFTCLLVVACTSIASAQNDAASPFGGSDSSIAQQWVQVDSAGTLHGRVDVPVAGGLRRADLVRIALLPLGGGEAATTVYGKTTLEGSFTIPQVSKGTYAMLVHSTDVLACYTVHVLPANGSETPDHLHVLAARTNSDFVMQRIRSYIPMQPSLPYAIKQFDTDPVSDRKPSSEGQVFADSTGAINGRLSLPAGSDGKSPAIRNMNVIVVQGDKSVAMAAVDGDGNFSVPKLTPGSYGLIAAGESGFAAVGFELTAPTTTSHSTRTTRFVSFNAAAAGETELNVEVVPGFAVESIQKELQPSENGDQEVIGEGVALDEFGWPVDPNAVPRGPTASSMGSAQAGSSGGGGGGSGGGGGLGGLGAIGLAAAALAAQDNNSVASPANP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ33</accession>
    <name>A0A518IZ33_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA polymerase sigma factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpoE_7</name>
        <name evidence="5" type="ORF">Mal33_43580</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000838">
        <property type="entry name" value="RNA_pol_sigma70_ECF_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01063">
        <property type="entry name" value="SIGMA70_ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="3">
        <location>
            <begin position="35"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="4">
        <location>
            <begin position="146"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV58340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="222" mass="25171" checksum="DD29B52BFDDF93F5" modified="2019-10-16" version="1">MPVSPSTALRYQQLDPDVRLMLRVRNDDATAFEELVHRYQNRLVQLLEHLAPRRDMAEDLAQDVFLRVYRARKSYEPGAKFSTWLFTIAGNVAKNSLRSASRRREVRATDAPVRNSGESDATLESLALAASGLMPARQIEGLERAEIVRMAIQSLNERQRMALWLSRFEELSYAEIADVMKMTPQAVKSLLSRARVNLKEILEPYVNQGAQLAASNRTEDPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ67</accession>
    <name>A0A518IZ67_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Conjugal transfer protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_43980</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GSP E family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001482">
        <property type="entry name" value="T2SS/T4SS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00437">
        <property type="entry name" value="T2SSE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T2SP_E" evidence="2">
        <location>
            <begin position="88"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="441" mass="49230" checksum="6DEB48CA44AA3089" modified="2019-10-16" version="1">MSRTMNPTAGRTELSRQEQFEQIKGRIHSKLVDKLDLSKVGDLKGDTLKREIRMVVEHLCDAEETLLNRQERERIVDEVLDETFGLGPLEIILKDKKVSDILINGPKNIYVEKEGQLQKSEVEFRDNKHLLQIIDRIVSKVGRRVDETCPMVDARLEDGSRVNAIIPPLALDGAAVSIRRFGSNPLKLEDLLNYKAFTPEMVMLLEGCIKARMNMIISGGTGSGKTTLLNTLSSFIPHDERIVTIEDAAELQLQQDHVVRLETRPPNIEGNGAVTATDLVKNALRMRPERIIIGECRGGETLDMLQAMNTGHDGSLTTIHSNNPRDAIARLETLVMMAGFEMPVKAIRSQIAGAVDVMIQASRLQGGKRRVTYITEIVGMEQDTIVMQDIYRYDQQGIGADGKAKGRFICTGVRPTFMDKLEGKGIRLPASAFRERVMMEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZG0</accession>
    <name>A0A518IZG0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Stress responsive A/B Barrel Domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_44990</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013097">
        <property type="entry name" value="Dabb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07876">
        <property type="entry name" value="Dabb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00886">
        <property type="entry name" value="Dabb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51502">
        <property type="entry name" value="S_R_A_B_BARREL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Stress-response A/B barrel" evidence="1">
        <location>
            <begin position="6"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="101" mass="11523" checksum="AFDB2BA0FF52F4D4" modified="2019-10-16" version="1">MTQLPIEHTVTFQLSHPAGSAAESEFLAAAAELASIPNVHNFQIRRQTSPKNPHRFGISMWFETAEHFAAYCDHPAHVEFVQERWLKEVTDFQESDFEPLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZW8</accession>
    <name>A0A518IZW8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC transport permease subunit MlaE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">mlaE_2</name>
        <name evidence="8" type="ORF">Mal33_46600</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the MlaE permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003453">
        <property type="entry name" value="ABC_MlaE_Proteobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030802">
        <property type="entry name" value="Permease_MalE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30188">
        <property type="entry name" value="PTHR30188"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02405">
        <property type="entry name" value="MlaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00056">
        <property type="entry name" value="TIGR00056"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="32"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="67"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="188"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="218"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV58636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="291" mass="31309" checksum="3DFD718CB3246222" modified="2019-10-16" version="1">MPSAASRSQRHSVSPQGMRAGLRDWASDWGKIVVSGVSTVGGIANFTLQMLRWIFTSLPRRETILPNFYQVGVLSLPVVALTGTFIGMVLAENSYYQFQSIGLESRLGGVINMTLVRELGPVLAATMLAGRVGSAMAAVLGTMRVTEQIDALATMGADPIHYLVVPRFLACIMLIPALTIMADFMGIVGGYFYSVVILGIDHAAYLNHSRQFVTGFDLFTGIFKSLFFGAVIAVVSCYRGFQAEAGAEGVGKAATSAFVHSFVMILVLDLVLGRLLNMVYFAFWPSGASLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZX3</accession>
    <name>A0A518IZX3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_46680</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="184" mass="19162" checksum="F10D2E8BF05FA9F6" modified="2019-10-16" version="1">MNETSSCCAGMKGFYGALAACLLCGIGYLVGSQNRDPGFSLPPHLINATASDSTDEFSIATGRVSGDAEGLFVLDHATGQLQCYVMYPRTAKFGAVFTTNVGEALAGRGEKGSKYVMVTGDASFPGGGRNGPAGTVLYVLDATSGAFVAYGLPFDRTMLTANRPQQGMLTPLDAGQVRQLAIRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZX8</accession>
    <name>A0A518IZX8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">2-oxoglutarate carboxylase large subunit</fullName>
            <ecNumber evidence="5">6.4.1.7</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">cfiA</name>
        <name evidence="5" type="ORF">Mal33_46720</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="6.4.1.7" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034029">
        <property type="term" value="F:2-oxoglutarate carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001882">
        <property type="entry name" value="Biotin_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003379">
        <property type="entry name" value="Carboxylase_cons_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000891">
        <property type="entry name" value="PYR_CT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00682">
        <property type="entry name" value="HMGL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02436">
        <property type="entry name" value="PYC_OADA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00188">
        <property type="entry name" value="BIOTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50991">
        <property type="entry name" value="PYR_CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0092">Biotin</keyword>
    <keyword evidence="5" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyruvate carboxyltransferase" evidence="4">
        <location>
            <begin position="6"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="Lipoyl-binding" evidence="3">
        <location>
            <begin position="532"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="522"/>
            <end position="544"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV58648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="609" mass="64934" checksum="922B1BDD9747138E" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J000</accession>
    <name>A0A518J000_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_46390</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015209">
        <property type="term" value="F:cytosine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030191">
        <property type="entry name" value="CodB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30569">
        <property type="entry name" value="PTHR30569"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="148"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="180"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="233"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="266"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="309"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="351"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="377"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="420"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="443"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="512"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="542"/>
            <end position="563"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="574" mass="62397" checksum="E426C8785A8880BD" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0F6</accession>
    <name>A0A518J0F6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glucosamine-6-phosphate deaminase</fullName>
            <ecNumber evidence="1">3.5.99.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">GlcN6P deaminase</fullName>
            <shortName evidence="1">GNPDA</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Glucosamine-6-phosphate isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">nagB_3</name>
        <name evidence="1" type="synonym">nagB</name>
        <name evidence="3" type="ORF">Mal33_48510</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:12172"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:75989"/>
            <dbReference type="EC" id="3.5.99.6"/>
        </reaction>
    </comment>
    <comment type="activity regulation">
        <text evidence="1">Allosterically activated by N-acetylglucosamine 6-phosphate (GlcNAc6P).</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-sugar metabolism; N-acetylneuraminate degradation; D-fructose 6-phosphate from N-acetylneuraminate: step 5/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.5.99.6" evidence="1"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00629">
        <property type="reaction ID" value="UER00684"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004342">
        <property type="term" value="F:glucosamine-6-phosphate deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006044">
        <property type="term" value="P:N-acetylglucosamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019262">
        <property type="term" value="P:N-acetylneuraminate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01399">
        <property type="entry name" value="GlcN6P_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01241">
        <property type="entry name" value="GlcN6P_deamin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006148">
        <property type="entry name" value="Glc/Gal-6P_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004547">
        <property type="entry name" value="Glucosamine6P_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018321">
        <property type="entry name" value="Glucosamine6P_isomerase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11280">
        <property type="entry name" value="PTHR11280"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01182">
        <property type="entry name" value="Glucosamine_iso"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00502">
        <property type="entry name" value="nagB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01161">
        <property type="entry name" value="GLC_GALNAC_ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="1" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucosamine_iso" evidence="2">
        <location>
            <begin position="10"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for enolization step" evidence="1">
        <location>
            <position position="67"/>
        </location>
    </feature>
    <feature type="active site" description="For ring-opening step" evidence="1">
        <location>
            <position position="136"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for ring-opening step" evidence="1">
        <location>
            <position position="138"/>
        </location>
    </feature>
    <feature type="active site" description="For ring-opening step" evidence="1">
        <location>
            <position position="143"/>
        </location>
    </feature>
    <feature type="site" description="Part of the allosteric site" evidence="1">
        <location>
            <position position="146"/>
        </location>
    </feature>
    <feature type="site" description="Part of the allosteric site" evidence="1">
        <location>
            <position position="153"/>
        </location>
    </feature>
    <feature type="site" description="Part of the allosteric site" evidence="1">
        <location>
            <position position="155"/>
        </location>
    </feature>
    <feature type="site" description="Part of the allosteric site" evidence="1">
        <location>
            <position position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="262" mass="28443" checksum="7FABBB84D047FFDD" modified="2019-10-16" version="1">MRIIIEKDAVAAAKRCAELIVEQIQKKPNSVLGLATGGTPVACYQVLIEMYREKTVSFAGCKSFNLDEYVGLAGDHPQSYRHFMQKNLFDHIDIDPAATHVPNGLAKDYEAYGEVYEQQIADAGGIDLQLLGIGSDGHIAFNEPGSSLGSRTRLKTLMPETVQDNARFFDSIDEVPRLAVTMGVGTILESRQCLLMATGGHKADAIAGAIEGPVTCQNTASALQLHRDAVYVLDEAAAQGLTRQAYYRSSEEMHRKVLAEGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0R5</accession>
    <name>A0A518J0R5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycerophosphoryl diester phosphodiesterase</fullName>
            <ecNumber evidence="2">3.1.4.46</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">glpQ</name>
        <name evidence="2" type="ORF">Mal33_49490</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.4.46" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008889">
        <property type="term" value="F:glycerophosphodiester phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030395">
        <property type="entry name" value="GP_PDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03009">
        <property type="entry name" value="GDPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="SSF51695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51704">
        <property type="entry name" value="GP_PDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GP-PDE" evidence="1">
        <location>
            <begin position="11"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="326" mass="36477" checksum="03846AB71532D01A" modified="2019-10-16" version="1">MGNGSPTEHAKIVIAHRGASGYLPEHTLPAKAFAYAVGSDFLEQDVVLSKDDVPLVLHDVHLDTVTDVRQRFPERARDDGRFYAIDLTLDELKSLSVSERFDPVTGQAVFPNRFPMGLSQFRIATLAEELELIQGLNDSTGRDVGIYTEIKRPVWHRQQGKDISQITLAVLNKYGYANRSDNVYVQCFDAVENRRLRDELGCQIRLVQLLEDDDWGRATAEYDLAAAESDLQTIAQYADAIGPSMNVVVVPHANRQGYLCTPLVELAHRCGLKVHPWTLRADALPQYVDSFERLIEIALFEADADGVFSDFPDVTVATRDRLFQAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0W4</accession>
    <name>A0A518J0W4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Aspartoacylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_50020</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016811">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007036">
        <property type="entry name" value="Aste_AspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043795">
        <property type="entry name" value="N-alpha-Ac-DABA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04952">
        <property type="entry name" value="AstE_AspA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039012">
        <property type="entry name" value="ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV58977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="305" mass="32517" checksum="AEEEBB799ABADE3E" modified="2019-10-16" version="1">MDLKQIEIVGRHPGPRLLILAGVHGDEYEPIAAVRRLADQIDREDLNGSVTLVPIANQPAYRRHSRIGADKLDLARTFPGSPNGTPTEQIAHAITKLIQQSDLMIDLHTGGLAMEISPLVGYMLVSDPATLQKQRRMATAFGLPIVWGTSAKLEGRSLSAARDANVPTIYAEWGGGGGCQADGVAAYTTGCLQVMADCKMASAPTAAAPVDRCVIEDDRDTSGHLQLNYPAPHGGFYEPTLALDSAVRPGDELGRLFDPFTSQATSICSTQTGRLITRRVLPPVEAGDCLAVILEDPAKTGTNNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J192</accession>
    <name>A0A518J192_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_51320</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007825">
        <property type="entry name" value="Major_OMP_Legionella"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05150">
        <property type="entry name" value="Legionella_OMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="38"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="372" mass="41275" checksum="5B9304C4696140B0" modified="2019-10-16" version="1">MKVWASICLGLVSVSFCNADSGQPIEAGILGAEDGGLWQQHLQRMEQLDQKMESLSQRLAAEEAESSVRYQPKRSRVPSSSLTRPGWNASVDYLNWTVRRRGLDYAITTDDSTRAVGAGDVHNVEYGSDSGIRAGLHYTTATGWEIGFRYTYLDIDATSSAESPAAGNMWATRSHPNENEEARRASASANLDYDVFDLELRRWFLINRVAAIQFLGGLRWASIDQNLRIDYDGDDFSDGQVFNDGQMDGFGVRLGALGQWQMSHGLSLFARGAGTLAYGKFENHLLETNRDGADTIVDVTDRYEQALPAIEAAVGLSWRSDHIELACGYELTNWFDLSDRSMFVDSAHEGAYSPKSTDLLLDGLFARMAFQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1B0</accession>
    <name>A0A518J1B0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Chaperone protein ClpB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">clpB_2</name>
        <name evidence="2" type="ORF">Mal33_51560</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001270">
        <property type="entry name" value="ClpA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00300">
        <property type="entry name" value="CLPPROTEASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="1">
        <location>
            <begin position="335"/>
            <end position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="612" mass="68219" checksum="8AA510A97E03F674" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1B1</accession>
    <name>A0A518J1B1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_51440</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="507" mass="55680" checksum="57ECCBFAEBFFE390" modified="2019-10-16" version="1">MQIPQRRQFFKTVGATGAVLALHELDFLGRLPVVSAAESQLPSTAVQFSPDIEPLVRLLEETPQEKVIERFAAQIQSGTSYQEVLAALLLAGVRNIQPRPSVGFKFHAVLVVNSAHLASVAAPDTDRWLPIFWALDYFKSAQARDVREGDWTMAAVDEAKLPPSHRANQAFREAMDGWDVEAADVAITSLCRSASAAEVFDLLSHYGCRDYRSIGHKAIYVANAYRTLQCIGWRYAEPVLRSLAYALLNHNGEPNPADHELGPDAAWRVTQQRLSSLDESWNHGRLDSAETLSLLDTLRSASPDEAVDASVQMLAEGIAPQSIADAIFLSAGEMIGQQPGIIALHSATTTNAMQYAYRTAFRDKTRRELLLQNAAFVPYFRESMRSRGKIADLRIDATPEKVDANGDTDLETIFQTVSNDRKQAATQMLGYLNGGGPPEAVINAARRLVFLKGNDSHDYKFSSAVLEDFYAVSPAFRNAFLANAAFLLPGSEDRDNGLVTKVRDALG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1F2</accession>
    <name>A0A518J1F2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Archaeal TRASH domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_51730</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011017">
        <property type="entry name" value="TRASH_dom"/>
    </dbReference>
    <dbReference type="SMART" id="SM00746">
        <property type="entry name" value="TRASH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021794962" evidence="1">
        <location>
            <begin position="22"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="domain" description="TRASH" evidence="2">
        <location>
            <begin position="174"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="domain" description="TRASH" evidence="2">
        <location>
            <begin position="241"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV59145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="387" mass="40290" checksum="9981BD2FF5102D31" modified="2019-10-16" version="1" precursor="true">MKRTLIITAFSLAISTSSVFGQTIQSQDHHAGHNHATTGTTKAREINQAGPHGGSLKQTDNLQIETIVSQGGLRMFVYDRTGHPVSVDKGRGAASVRVEGHAKRYRYDLLPDGKGALTAPVNLSQLAGRQIDVAIQLVGMKAAGRSVVSFNEVATVPASEQQLAAAAIARQKICPVSGKPLGSMGDPVTVDINGQKLYVCCAGCVGAVKSNPAKYATGRPQITVTTATQADAAAIAAQKVCPVMDEPLGGMGTPIKVMVGDKPTYLCCKGCIKKVQAEPAKYLAMVHGKQMGSGGTEESGNVVAAGTEQVREGIFKVVAADAPFIAAQKKCPVMDEPLDAMGGPYKVNAAGKAIYICCPGCAKKIAAEPNKWLAVLKSQGVEAPLIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1G5</accession>
    <name>A0A518J1G5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CDP-paratose 2-epimerase</fullName>
            <ecNumber evidence="2">5.1.3.10</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rfbE</name>
        <name evidence="2" type="ORF">Mal33_52190</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="5.1.3.10" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047732">
        <property type="term" value="F:CDP-abequose epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="5"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="349" mass="38984" checksum="87EFF7D38ECC67D0" modified="2019-10-16" version="1">MKKLLVTGSSGLIGSEVCLYFAAAGWKIHGVDNNQRAVFFGPQGDTRWNQQRLAGRIEGFEHHEVDIRDREAVLALVDKVRPDAIVHTAAQPSHDRAAAIPFDDFDTNAVGTLNLLEATRRACPESPFAHMSTNKVYGDRPNSIALEELETRWDYADPQYANGIPESFSIDQSKHSLFGASKVAADVMVQEYGRYFNLPTCCLRGGCLTGPNHSGVELHGFLSYLVKCNLEGKPYTVFGYKGKQVRDNIHSEDVARFIAAFIETPRVAEVYNIGGGKANSCSILEAFQITQRFTGREQQYSYSDENRIGDHICYYSDLGKMRTDYPGWDITISLEDTIEQIVAAWKQRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1R4</accession>
    <name>A0A518J1R4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Bacterial type II secretion system protein F domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Mal33_53010</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.81.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018076">
        <property type="entry name" value="T2SS_GspF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042094">
        <property type="entry name" value="T2SS_GspF_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00482">
        <property type="entry name" value="T2SSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="58"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="223"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="255"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="domain" description="T2SSF" evidence="7">
        <location>
            <begin position="116"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV59273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="283" mass="30724" checksum="6D943F87EA0087EB" modified="2019-10-16" version="1">MTSVLIPASGLIAAIAGLAIYWVHAARRESILHRLSAADAVVRPAVVSEAPFARRHRLIPWGIAIPIGIALGWLGNWPWNIAVGIAIIISFIASEADAWIYQWRLARIESQLADAIDVLVASVSAGASLQAALQQASEYTPRPLRDEITEMVARLRLGDAPPDVFDLLRQRVPTETFRLFSMTLTVNWQVGGALAETLSAIGGTIRDRLAIARQIRTLGTQGTLTTLTVLAVVWLMAAMMWQADPPRFLGFVHSTVGSWLVAVSLFLQGIGVALVSRISRPKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IM17</accession>
    <name>A0A518IM17_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">2,3-bisphosphoglycerate-independent phosphoglycerate mutase</fullName>
            <shortName evidence="8">BPG-independent PGAM</shortName>
            <shortName evidence="8">Phosphoglyceromutase</shortName>
            <shortName evidence="8">iPGM</shortName>
            <ecNumber evidence="8">5.4.2.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8 14" type="primary">gpmI</name>
        <name evidence="14" type="ORF">Mal33_00850</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>(2R)-2-phosphoglycerate = (2R)-3-phosphoglycerate</text>
            <dbReference type="Rhea" id="RHEA:15901"/>
            <dbReference type="ChEBI" id="CHEBI:58272"/>
            <dbReference type="ChEBI" id="CHEBI:58289"/>
            <dbReference type="EC" id="5.4.2.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="8">Binds 2 manganese ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 3/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the BPG-independent phosphoglycerate mutase family.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.12" evidence="8"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00186"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046537">
        <property type="term" value="F:2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006007">
        <property type="term" value="P:glucose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
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            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
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                <person name="Peeters S.H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
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    <sequence length="962" mass="107722" checksum="82100454C536C262" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMK3</accession>
    <name>A0A518IMK3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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    <organism evidence="1 2">
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            <taxon>Planctomycetia</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="60" mass="6331" checksum="9DC8A6E686485913" modified="2019-10-16" version="1">MSPANPPTAATMKPGDLLHDLDRRQDDVLTQLDELQAKLDGVLAELGITAMGDGDLDAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMU6</accession>
    <name>A0A518IMU6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Mal33_03600</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0382 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006696">
        <property type="entry name" value="DUF423"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43461">
        <property type="entry name" value="PTHR43461"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04241">
        <property type="entry name" value="DUF423"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="14"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="60"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="85"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="113"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV54406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="140" mass="14794" checksum="B9139666386237F2" modified="2019-10-16" version="1">MNANQASGIAVRRVLMIAGFLGASGIMAGAFTAHGLETWLIDQGYEEVAAKRVGQADVSVRYHLLHAVALVAMAAVAGHYNRGKYLTIITLMTLGTLLFSGSLYLLVALNLPVMGAITPLGGLAWIAAWIMVALPRKSND</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMV3</accession>
    <name>A0A518IMV3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_03740</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="71" mass="8153" checksum="7CF994696033A6A9" modified="2019-10-16" version="1">MPTIAEEWKEEGRQEGRQEGRQEGAMIGQVLAYQQFLGRPTSGEEALLAMESGELRALFQQLDAEFRKLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMX7</accession>
    <name>A0A518IMX7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_04020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="150" mass="15070" checksum="ED894EC941C84DC3" modified="2019-10-16" version="1">MKPTSLTAGRSTRLRSTVSIAIVSALLLSTAGCGPTGKRIATAPVKGKVTYKGAPVTTGTVMFIPTTGGPPATAEIQPDGTYSLKTYDPGDGAVLGDHTVAVTAMDLPAGTPEDPVAAPTMLVPPEFGNPSTSGLTATVVEGDNALDFDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMX8</accession>
    <name>A0A518IMX8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_03910</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022220025" evidence="1">
        <location>
            <begin position="21"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="135" mass="15201" checksum="E53738799C895612" modified="2019-10-16" version="1" precursor="true">MLARIACLSLLALSAVPAFADHPYGSLDLPRVELFDWVERIEPLSYRARYNRPRYVGGKIAFYIAPSSQGAMSWHENVHNGNYRNHAGPTIKKYYYPKPWEALQVGPRSATQGQYKVLEVSPAEVESVIIEPPAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IN16</accession>
    <name>A0A518IN16_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Transcription termination/antitermination protein NusA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">nusA</name>
        <name evidence="10" type="ORF">Mal33_04330</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Participates in both transcription termination and antitermination.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the NusA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006353">
        <property type="term" value="P:DNA-templated transcription, termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031564">
        <property type="term" value="P:transcription antitermination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1480.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00945_B">
        <property type="entry name" value="NusA_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010995">
        <property type="entry name" value="DNA_repair_Rad51/TF_NusA_a-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025249">
        <property type="entry name" value="KH_dom_NusA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009019">
        <property type="entry name" value="KH_sf_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030842">
        <property type="entry name" value="NusA_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036555">
        <property type="entry name" value="NusA_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013735">
        <property type="entry name" value="TF_NusA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010213">
        <property type="entry name" value="Tscrpt_termination_fac_NusA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22648">
        <property type="entry name" value="PTHR22648"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13184">
        <property type="entry name" value="KH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08529">
        <property type="entry name" value="NusA_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47794">
        <property type="entry name" value="SSF47794"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54814">
        <property type="entry name" value="SSF54814"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69705">
        <property type="entry name" value="SSF69705"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01953">
        <property type="entry name" value="NusA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6 7" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 7" id="KW-0889">Transcription antitermination</keyword>
    <keyword evidence="5 7" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="1 7" id="KW-0806">Transcription termination</keyword>
    <feature type="domain" description="S1 motif" evidence="9">
        <location>
            <begin position="104"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="378"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="382"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="454"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="477"/>
            <end position="491"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV54479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="511" mass="55575" checksum="A287CDD5EB54190D" modified="2019-10-16" version="1">MNPQDLLRYVDSLHREKNIDPSLLFSAIEAALATAARRHYGEEADIVVRIDHDSGKIHAEIDGAPLDQDQVGRIGAQTAKQVIIQKVREAERDALMAEYREQIGQMVSGVIQRADGGVATVQLGNVEAILPRSEQISGESLHANERVRAVVFEVRATGNRVRVVLSRTRPQLVKCLFEQEIPELSEGVIAINSISREPGYRSKVAVSSTDSQVDPIAVCVGYRGSRIKSVREELAGEHIDVVRYSDDPQILIPNALQPAEIEQVLLCNMIGRAIVLVQEDQLSLAIGRRGQNVRLASKLCGWDIEIMTGGELEEQIERAVTGFSQLEGMTEDLAQQLVEQGYLSYDDLSVIEPETLMQMGGLTAEQVDVIVEQAETQAEEAEAAATEERKKRKQEREAAANAAASGEQPPAAEEQVVEGTEAEESEDSVAEVSEETQHGDGAESPAADEAGADGEAEASVEEVENVIVESEPIDESTEQDSDNKNVAVENINEEGEAEQLASDNVEDPDKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IN36</accession>
    <name>A0A518IN36_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_04460</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="415" mass="45748" checksum="C5551DCB9D3206F4" modified="2019-10-16" version="1">MKPPQRAQGATILYLDPSLRSHQGHHANVGEAITSAARAQEHRVHVAVSQSKSDVCEGEKVFSRNVYSDMKRNPDRLIDRIRLKMATATVCKEVRPLLRRIQPNLIYANSVNAVVCEGILQALRTTYLPGRAPFLIAELPFRCEPGPRHFYGQQLAAMFRRLKRSAARQNTAVASNPLDRFAPITVDQQTASLLAQTVDAEIGVLPSPYAVRTRRQLVAGQPPQPLRIGSVGHQRESKGFHYLPAIFETLSNLKNSIQWVVQHQNDSDPTTLEKLRQMQSQGFQIELIDEELTRDAYEQLLLGLDIILLPYKPEHYQSMISGICYEGLSQGNIVVAPRHTSVGKIIGEFQPLSPQFDEWTVDSISTALDAAIDSAASLNAAAIQGASLFAQAHGPDAFASAIASKAVDDVAFKAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IN40</accession>
    <name>A0A518IN40_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Elongation factor 4</fullName>
            <shortName evidence="5">EF-4</shortName>
            <ecNumber evidence="5">3.6.5.n1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Ribosomal back-translocase LepA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">lepA_1</name>
        <name evidence="5" type="synonym">lepA</name>
        <name evidence="7" type="ORF">Mal33_04480</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>GTP + H2O = GDP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="3.6.5.n1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Peripheral membrane protein</topology>
            <orientation evidence="5">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.n1" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045727">
        <property type="term" value="P:positive regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03709">
        <property type="entry name" value="lepA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00071">
        <property type="entry name" value="LepA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006297">
        <property type="entry name" value="EF-4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038363">
        <property type="entry name" value="LepA_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013842">
        <property type="entry name" value="LepA_CTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035654">
        <property type="entry name" value="LepA_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
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    <name>A0A518INJ8_9BACT</name>
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Boedeker C."/>
                <person name="Pinto D."/>
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                <person name="Rast P."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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</entry>
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    </dbReference>
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        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="13"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-Casp" evidence="2">
        <location>
            <begin position="234"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="444" mass="49805" checksum="7CA92B139831D64B" modified="2019-10-16" version="1">MKLIHHGGHLGVTGSCHQLWTDDEHSLLVDCGTFQGDDARDHPNPEIKFSLRGIESLLLTHVHIDHCGRIPHLIAAGFEQPIYCSGPTARLLPLVMQDALKIGFTRNQRLIDKFNDKIAKLLQPLPYHQWHPIQGGCKLRLRPAGHVLGSTIFEVELPNGQMAVFSGDLGPRHAPLLTEFSSPERADLLVMESTYGNRIHEGRADRQSRLEAVLRKTLDDKGVTIIPAFSLGRTQDILFEMNGIFEAIQKQQGRSLMKQVDVIVDSPLASRFTQIYDDLQEFWSAEAQGVLKTDDQPLVFENLTTVGDHQAHLATLDQLVKHKLPAVVVAGSGMCTGGRVMNYLRRLIGEPTTDIVFCGYQARGTPGSYIQRGSDWVRLDGRKYQIRADVHQLSGYSAHADQRDLLRFVAGFTEKPYQIRLVHGEYHVRKALEAELDQRGYHVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INM2</accession>
    <name>A0A518INM2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cysteine desulfurase</fullName>
            <ecNumber evidence="3">2.8.1.7</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">iscS_1</name>
        <name evidence="3" type="ORF">Mal33_06420</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="2.8.1.7" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031071">
        <property type="term" value="F:cysteine desulfurase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010969">
        <property type="entry name" value="Cys_dSase-rel_unknwn_funct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016454">
        <property type="entry name" value="Cysteine_dSase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005572">
        <property type="entry name" value="NifS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01977">
        <property type="entry name" value="am_tr_V_EF2568"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_5" evidence="2">
        <location>
            <begin position="5"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="379" mass="39556" checksum="59A0E4E7B4B7E49C" modified="2019-10-16" version="1">MNQRIYLDNAATSWPKPPGVAEAIAAEITEIGAAAGRGAYAAAMSAEQVVANCRAAVAQMINAQAAEIALTCNGTHSLNIAIQGVLRRGDHVVTTQIEHNSVLRPLAWLQESRDVSVTVVPCDRFGFVDVDAIAAAIRDDTRLVAVSHASNVTGAVQDLAAIGAIVRQHPALFLVDAAQSLGHLPIDVQAMAIDMLASPGHKGCLGPLGTGVLYLENSIQSQVQPLMYGGTGTDSDRMEMPAGMPGRHEAGNLNVPAIAGLLAALRWSAGNETEDSSGPLADRLADALAELPGVEVFRDRARSHVAVVSVAIDGWQPTDAAGVLDAQFGIQSRAGLHCSPRIHEALGTSAGTLRFSLGRFTRQAEIDRAIDAVGQLVGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INU4</accession>
    <name>A0A518INU4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_07150</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="207" mass="23050" checksum="8484563556D1331C" modified="2019-10-16" version="1">MTWTLTDDIAEKNAGVWTLRGPLQAPENGWQIGCGESSELDRLLALTSSVAMPVFQEADRPLEDLVARYRPSAEAGISLDIRYQLLNVSPSRLVLQATYAIQTREFETHPSLQIAIPGLPETELATINRAHVGAMHLAVLMQPCDLAQARRVDAPQDGGIQFYGDFMERGVIRKCRLRLILSPLSQQELQAEEEFEALMREPLPLVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP13</accession>
    <name>A0A518IP13_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">prkC_2</name>
        <name evidence="10" type="ORF">Mal33_08010</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="533"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="84"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="388"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="390"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="440"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV54836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="571" mass="60933" checksum="B6E0D8421F2D3F14" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP74</accession>
    <name>A0A518IP74_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_08290</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="46" mass="5405" checksum="EF6A535BCD25647F" modified="2019-10-16" version="1">MTKRRGFTSRTPLPEHRFARSTLPYKLRLGRVKCSDHCTGVKSDWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP94</accession>
    <name>A0A518IP94_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_08620</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="352" mass="38819" checksum="CCA1739E372799D3" modified="2019-10-16" version="1">MVSVRRLGCNGFLLGLISLVGVACGNDPIRVDADLLPGIGGYSTAEADLGWLPAGKKVDVEVRVVNRLSDVVQFDRLKLDGSLNKAEATGNSIPVGGELTIRAALTIPNYSHEVDQSIAIYLQRDGKRSARETVRLRFQVSELLRFHTKTAQFSRDSSDNQCVERIPVTITKPIDAAKVSVTGTGDFRNARGAIVHWQDRDWLQFEVDREDPIQAELAGTLTIEDPVSKRKDMITCLVRYRVPVTVRPGLLFARLASDEKSYAVTAFVRLYPTEESAARFAETKTATQAPAVVAAHLGEHPMDVTTHPLGAGVYRVEAVVPERFVEEAESIQWQVKTDGKVYYVNTRVGFPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPP6</accession>
    <name>A0A518IPP6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_10080</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="74" mass="7924" checksum="9E7EC3C11536237E" modified="2019-10-16" version="1">MAEEKLRGGFECWGTWGWCGGWAVSGAPAAQSPVASNGELLASPLPLRFRAIGRTPTQLTRAGPTNRKKCESFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQ23</accession>
    <name>A0A518IQ23_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_11420</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="30"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="420"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="491" mass="54363" checksum="DB830E08CCB1A3EF" modified="2019-10-16" version="1">MEIVIQILLGLSVIGFGVLMWKSAERWTWVPLVIAPIVFIEAVVFMGLVAMSSKSRVAWQKISVELEERLDKATVEEEELKYGVIGLEGDQRAVVPIELALQKLRVEAGRVWRGLSPQGAAQGQFTLNMPQNQAAAAAVDPAAEPADPAAAPADGAESSAIPVDTIVFAFSEVMDPNQNRVPQTFLGQYLVTQSSPQSLTLQPLRALSALSKRQQQGISQAQSWAIYEVMPLDGHEPFFVEASRKRDEAIFGDADEEFLNAALAGKIPAEVLQSYLKDGKQAQSDDPPEAKWRKIKLLKDHSVIVDGSGQRTATEGSYFDLLGQAVDSRLQLADGDEVQFKAGTELVFKYEEATELISTGVAELIDEIYVRPLNDYDEIERHVFERLDVLAEKVVVLNREIAIMKKVKEANDTMLVSGQEDKLKLEAELAQHRVEKAAIEAYAKELQQRKAAMRTQLAALYQDNVKIVRNLERVQMQLKQQIDQRTAAAGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQ97</accession>
    <name>A0A518IQ97_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Flagellar biosynthesis protein FlhA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">flhA</name>
        <name evidence="9" type="ORF">Mal33_12030</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044780">
        <property type="term" value="P:bacterial-type flagellum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.540">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042194">
        <property type="entry name" value="FHIPEP_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042193">
        <property type="entry name" value="FHIPEP_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042196">
        <property type="entry name" value="FHIPEP_4"/>
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        <property type="match status" value="1"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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            <end position="28"/>
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            <end position="53"/>
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        </source>
    </evidence>
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        </source>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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        <source>
            <dbReference type="EMBL" id="QDV55233.1"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <sequence length="701" mass="76158" checksum="9E7F26FDFBF25B20" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQL1</accession>
    <name>A0A518IQL1_9BACT</name>
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        <submittedName>
            <fullName evidence="5">Cation efflux system protein CusB</fullName>
        </submittedName>
    </protein>
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        <name evidence="5" type="primary">cusB_1</name>
        <name evidence="5" type="ORF">Mal33_13390</name>
    </gene>
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        <dbReference type="NCBI Taxonomy" id="2527990"/>
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            <taxon>Planctomycetes</taxon>
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    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
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                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5 6">Mal33</strain>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="775" mass="85476" checksum="B69948086D3A44E1" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
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    <name>A0A518IR40_9BACT</name>
    <protein>
        <submittedName>
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        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rhaB</name>
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    </gene>
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        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="project" value="UniProtKB-EC"/>
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    </dbReference>
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    </dbReference>
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            <dbReference type="ARBA" id="ARBA00023308"/>
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        </source>
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            <dbReference type="Pfam" id="PF02782"/>
        </source>
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            <dbReference type="EMBL" id="QDV55555.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="496" mass="53595" checksum="37A07B74DBA2C05D" modified="2019-10-16" version="1">MASAPVHLAVDLGASSGRVLAGCIEDGQLKLSELHRFANDPVHVQGRMYWNLLGLWQEIRKGLSLAAAGEAKVLSVGVDTWGVDYVFLDANGDLIGPGYHYRDARTRGMFPKAFERVGREEIFAETGLQFMELNTAYQLLAARLENSPVLDIANQMLMIPDFFHWLLTGKAAIEYTNATTTQLYNTQQQGWSQKLLKAFDLPTRVFSDVVQPGTVLGPILGGQGGVPGLEGVPVVLPATHDTGSAVVAVPADNFAPAQPDWCYISSGTWSLMGCEIPEPLINDRCAELNFTNEGGVQGSTRLLKNIGGLWIFQQIKASLERRGQTLDWPSMVQAAADAKPFQLLIDPDCPDFAAPACMVDAIAAFANRTGQPAAADNGVLFRGALEGLALRYRTCLGWLESLTGTTINTIHILGGGAQNALLCQMTADACRRRVLAGPVEATAIGNIVMQMVGLGQIGSIQEGRQLIRDSFQPVVYEPQDPDPWDAAAERFEKLDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRD4</accession>
    <name>A0A518IRD4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_16170</name>
    </gene>
    <organism evidence="4 5">
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        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021721977" evidence="3">
        <location>
            <begin position="21"/>
            <end position="1066"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="950"/>
            <end position="968"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="975"/>
            <end position="991"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="997"/>
            <end position="1015"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1031"/>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV55639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1066" mass="118019" checksum="40428DD392B3597B" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRQ1</accession>
    <name>A0A518IRQ1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Polyhydroxyalkanoic acid system protein (PHA_gran_rgn)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_17560</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013433">
        <property type="entry name" value="PHA_gran_rgn"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09650">
        <property type="entry name" value="PHA_gran_rgn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="100" mass="11391" checksum="41D3C625E7DE5574" modified="2019-10-16" version="1">MPKVNSQVANTLGKEKAKEKLDYMAERMERDYGDKVKNMQRVWDEDTLTISFEAMGFKIKSLLSVGEDVVDVESQLPLAAMPFKGMVQTRMVDTLQKMLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRV2</accession>
    <name>A0A518IRV2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_18060</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011446">
        <property type="entry name" value="BBP7"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07585">
        <property type="entry name" value="BBP7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021840646" evidence="2">
        <location>
            <begin position="27"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="527" mass="58399" checksum="6E39A9704FAEB1D5" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRZ0</accession>
    <name>A0A518IRZ0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 10">ATP-dependent Clp protease proteolytic subunit</fullName>
            <ecNumber evidence="5 8">3.4.21.92</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Endopeptidase Clp</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">clpP_1</name>
        <name evidence="5" type="synonym">clpP</name>
        <name evidence="11" type="ORF">Mal33_18200</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 9">Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 10">Belongs to the peptidase S14 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.92" evidence="5 8"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07017">
        <property type="entry name" value="S14_ClpP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00444">
        <property type="entry name" value="ClpP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001907">
        <property type="entry name" value="ClpP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023562">
        <property type="entry name" value="ClpP/TepA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033135">
        <property type="entry name" value="ClpP_His_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018215">
        <property type="entry name" value="ClpP_Ser_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10381">
        <property type="entry name" value="PTHR10381"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00574">
        <property type="entry name" value="CLP_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00127">
        <property type="entry name" value="CLPPROTEASEP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00493">
        <property type="entry name" value="clpP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00382">
        <property type="entry name" value="CLP_PROTEASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00381">
        <property type="entry name" value="CLP_PROTEASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5 8" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 8" id="KW-0720">Serine protease</keyword>
    <feature type="active site" evidence="6">
        <location>
            <position position="98"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="5">
        <location>
            <position position="98"/>
        </location>
    </feature>
    <feature type="active site" evidence="5 7">
        <location>
            <position position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QDV55841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="197" mass="21853" checksum="CC3D9A3941C8605D" modified="2019-10-16" version="1">MPLIPYVVEKSGREERVYDIYSRLLKDRIIFLGSQVNDDVANSLVAQMLFLQSDDPKADIHLYINSPGGSVSAGLAIYDTMQFVSCDVATYCIGQAASMGAVLLTAGAKGKRYALPNARIMIHQPLAGMQGTAEEIRIHAEEFRRIKRKLNEILIHHCGKSMEEIEKDTDRDRFMSADEGVEYGLIDKVVASVADKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IS04</accession>
    <name>A0A518IS04_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_18300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.620.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012348">
        <property type="entry name" value="RNR-like"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="498" mass="56489" checksum="B3EA3A8572AFB9DC" modified="2019-10-16" version="1">MNGCSDCAVCVIASHGEIDAGKLHALRFHIIDENDVVESCSKLQIPSRSSIAYLPHDPIMKNPIRMLMLTLSLAVVCSQAMATNVMCPVLRDREATDEYVTTYQGKTVRFCCNECRQEFEQNAELYASEVPQLQNLAWSDRLRDFFDTNTRYVAIGLLLTLLIGLRAYGYQATNRIGDDPPTEAAIDVAEQFAQPASLPSERLPLRQRLLTAKVSPVIPLVILCGYLGYEIWSLRDHIASTALAEEIHFATFYDFGTPPVPERPADLENRLSGSYYRGNDERSPRLFNEGNYRTATFHIQLVDAQGTPLVAGDDISDREVFLNLDIDRPPFTPDFLYLPRVMETMFLTRKSEIFLGRDGPVEDAVMLETVEPMQRWNARFSLGKISCCSKELRGVVYVCEQRFYKPHWWSSSEQVGGARMHYGIRYDLATEDGRLTDASDMYMGALYRTRKFPKWKVPMTEWFSHEPIPELPGPNVEDKELLGIDDHEADRGVIAETL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IS22</accession>
    <name>A0A518IS22_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_18770</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="42" mass="4579" checksum="BB4D822F7C9D53AA" modified="2019-10-16" version="1">MHQGGKDQPSLIRSFLLEGFRIFKAGAGGTCRCVNRSGQLKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IS90</accession>
    <name>A0A518IS90_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">50S ribosomal protein L27</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">rpmA</name>
        <name evidence="7" type="ORF">Mal33_19020</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the bacterial ribosomal protein bL27 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00539">
        <property type="entry name" value="Ribosomal_L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001684">
        <property type="entry name" value="Ribosomal_L27"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15893">
        <property type="entry name" value="PTHR15893"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01016">
        <property type="entry name" value="Ribosomal_L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00063">
        <property type="entry name" value="RIBOSOMALL27"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00062">
        <property type="entry name" value="L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV55923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="82" mass="8818" checksum="C2E96ED453B0B396" modified="2019-10-16" version="1">MAHKKGQGSSRNGRDSNAQRRGVKKFGGEKVAPGNIIIRQVGTKVHPGRGVGMGNDYTLFALIDGVIKFDREGRRVNVVDAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISC6</accession>
    <name>A0A518ISC6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_19600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="PTHR14614"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="240" mass="27029" checksum="4AD3701AD1AA857B" modified="2019-10-16" version="1">MTPSVLNRPANQVDGDNAAWIRKLEARASARYAWHYEPVMAAGKRRRFASATCPDDLLVAATKRQEAGEQGVEEPFWATVWQAAVGLDWFIETLDLPGRQVLELGAGTGRAGLAAALRGAEVTITDGMTDPLLLAQLSTWDLPNCHVRRLRWGEEQLDRKFSLILGSDVTYNRQFWAELEVAMRQHLEPGGVILFSDPCRLIANEFRDWIGPRGWLYSESHVPHCQDAHRSIRIMQLRLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISF9</accession>
    <name>A0A518ISF9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_20010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022173605" evidence="2">
        <location>
            <begin position="28"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="155"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="174"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="541" mass="57903" checksum="5663871CB1C0853C" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISX5</accession>
    <name>A0A518ISX5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">BNR/Asp-box repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_21420</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011040">
        <property type="entry name" value="Sialidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036278">
        <property type="entry name" value="Sialidase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13088">
        <property type="entry name" value="BNR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50939">
        <property type="entry name" value="SSF50939"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sialidase" evidence="2">
        <location>
            <begin position="226"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="503"/>
            <end position="524"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="524" mass="56277" checksum="93E514B90C1ED394" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IT04</accession>
    <name>A0A518IT04_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptide methionine sulfoxide reductase MsrA</fullName>
            <shortName evidence="4">Protein-methionine-S-oxide reductase</shortName>
            <ecNumber evidence="4">1.8.4.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Peptide-methionine (S)-S-oxide reductase</fullName>
            <shortName evidence="4">Peptide Met(O) reductase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">msrA3</name>
        <name evidence="4" type="synonym">msrA</name>
        <name evidence="6" type="ORF">Mal33_21900</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>[thioredoxin]-disulfide + H2O + L-methionine = [thioredoxin]-dithiol + L-methionine (S)-S-oxide</text>
            <dbReference type="Rhea" id="RHEA:19993"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:58772"/>
            <dbReference type="EC" id="1.8.4.11"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 4">
            <text>[thioredoxin]-disulfide + H2O + L-methionyl-[protein] = [thioredoxin]-dithiol + L-methionyl-(S)-S-oxide-[protein]</text>
            <dbReference type="Rhea" id="RHEA:14217"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="Rhea" id="RHEA-COMP:12313"/>
            <dbReference type="Rhea" id="RHEA-COMP:12315"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16044"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:44120"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.8.4.11"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the MsrA Met sulfoxide reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.8.4.11" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033744">
        <property type="term" value="F:L-methionine:thioredoxin-disulfide S-oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008113">
        <property type="term" value="F:peptide-methionine (S)-S-oxide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01401">
        <property type="entry name" value="MsrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002569">
        <property type="entry name" value="Met_Sox_Rdtase_MsrA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036509">
        <property type="entry name" value="Met_Sox_Rdtase_MsrA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01625">
        <property type="entry name" value="PMSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55068">
        <property type="entry name" value="SSF55068"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00401">
        <property type="entry name" value="msrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PMSR" evidence="5">
        <location>
            <begin position="5"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV56209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="169" mass="19135" checksum="7D5F0E86F29948D6" modified="2019-10-16" version="1">MNERAVLAGGCFWGMEDLFRKQPGVVATRVGYTGGEVPNATYRNHGQHAEAIEVIFDPSQTNFRKLLEFFFQVHDPTTPNRQGNDIGSSYRSAIYYTNDDQKRVATETIADVDASGIWPGQVVTEVEPAGDFWEAEPEHQDYLLRNPNGYTCHFLRPDWVLPQRPEASQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IT27</accession>
    <name>A0A518IT27_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_22210</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="102" mass="10915" checksum="C23C32C01D50F407" modified="2019-10-16" version="1">MNQMTSIADGNNLAVKTAAQDANAVQDAVNLIAIVGCFHRHLLALRQAGLCGDDLNNHPASLAFVSKLNSLCRMTTEREMAAFSAIDKLAEGESVEYDVIPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IT36</accession>
    <name>A0A518IT36_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cupin domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_22290</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin_2" evidence="2">
        <location>
            <begin position="37"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="105" mass="11329" checksum="9CB6846D1A140B04" modified="2019-10-16" version="1">MSEHNFQIRQLSDELQPPESGKQNVVLTDDDNTKVVLFAFAAGDGLKEHVAPLPAIIQIIKGEAELTVGEETVAGKPGTWIQMAAKTPHSIKASTPLVMLLTLLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITI1</accession>
    <name>A0A518ITI1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_23890</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="157" mass="17607" checksum="34F425687AB0CEE9" modified="2019-10-16" version="1">MSTVLRLQLQNNRIARLTESDWAKAPSPAPMPKPVQPKPHWIKGQDFADQLACFAMLLDISKRQPEEDAKRTILAALESILLLWWRVETRRPNVSPLPENCPKKLYDHGCIRLAELHDLQVAFKPAATAAHLFQVADSCGKTMTVQFQDLLDGGAAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITJ3</accession>
    <name>A0A518ITJ3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_23950</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="124" mass="13874" checksum="7E73581AF403013C" modified="2019-10-16" version="1">MKSDLDITVVDPVDEIGRPRNIEPYLYDNIERTWLRHRFPSVKTNLQELGAALLAYRMNPVSPKPVKRFEQLGVAQYEIGALDAEVAFGEMLDFTLKCEGEAVQVSAQNDAILDQIAIIGAIEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITK0</accession>
    <name>A0A518ITK0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_24040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="118" mass="13188" checksum="474E3100B36036BC" modified="2019-10-16" version="1">MNRQKLIDEISEQLAILTHKIKLQNGLNLTDLNIHAENFFRDFLNLLHGFSLCNCNADNQNAATIDLRDDENRIAIQVTSNSQRAEGDTHNTSRRTFKAWLSPNAPPGGDLAVINFGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITK7</accession>
    <name>A0A518ITK7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acetolactate synthase isozyme 1 large subunit</fullName>
            <ecNumber evidence="3">2.2.1.6</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ilvB_2</name>
        <name evidence="3" type="ORF">Mal33_24150</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TPP enzyme family.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.6" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003984">
        <property type="term" value="F:acetolactate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012001">
        <property type="entry name" value="Thiamin_PyroP_enz_TPP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045229">
        <property type="entry name" value="TPP_enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18968">
        <property type="entry name" value="PTHR18968"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02776">
        <property type="entry name" value="TPP_enzyme_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TPP_enzyme_N" evidence="2">
        <location>
            <begin position="1"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="179" mass="19386" checksum="6AB485666ADE0032" modified="2019-10-16" version="1">MKASDLFVKALENEGVEFVFGIPGEENLDFLDSLSRSNIRLILTRHEQAAGFMAATYGRLTGKSGVCLSTLGPGATNLVTAAAYAQLGGMPMLMITGQKPVKTSKQGQFQIIDIVDMMRPLTKYTRQLVSGANIPSRVREAMRLAQEEKPGAAVDYPQVAAKTARFGTVFALVVFHFAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITL7</accession>
    <name>A0A518ITL7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_24240</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="114" mass="12717" checksum="4CC6D764C465247F" modified="2019-10-16" version="1">MDDLSSESVNLQPWLLLSDAGPACWQMQDDRIALAMFTDQAKAQQYANDAQLQNSQCLQPSPIDLVRTMAMCVEGAIEVAVLDPDQNSARRVFDLPVILKKVRDDLRAGKPLTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITT8</accession>
    <name>A0A518ITT8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_24920</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="104" mass="11588" checksum="5603026EE54B9757" modified="2019-10-16" version="1">MTRVTKAQLSRLVEAIGRKRTIDSESRALESEIKNLRKIAYDDLRSTGNPTAKRSGFLLRWSTAKGRVAWKEEFIREVGSEKATQLAENVGTVQSIDVVPAEVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IU00</accession>
    <name>A0A518IU00_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GDP-mannose-dependent alpha-(1-6)-phosphatidylinositol monomannoside mannosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">pimB_2</name>
        <name evidence="3" type="ORF">Mal33_25580</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="61"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="185"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="748" mass="83883" checksum="E7E2093812724C20" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUR4</accession>
    <name>A0A518IUR4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_28320</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021798457" evidence="2">
        <location>
            <begin position="24"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="384"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="413" mass="46222" checksum="DDE158461F5C37EA" modified="2019-10-16" version="1" precursor="true">MSTRCLTTCILLAILCNNRPVVAQEGSFLDAIRQRIQSAADNQTEEEKEQTRKKLESLFSIVTEGAREIYRTLPDDSQKAIDQRRQAWMDAMASGVDDLTGDDIERWLDNSDNVILRSLSRGGDAPSVNAQSRTDLLPEQWWYGKQNRTLAQLLTQPPETIIRREDLPGPPIWFVNGITTKKAEAIAMADEIAEQLGRRVHLLHNPTFMEPPNHSGLDVEGYGTDDLSECLHDRLWPATVFNKLNRMDAEQLQAMLDDGQTLQGNPTTRQLAYVLLTAREPISLITHSQGCIIARNAMFTMAMLGRREQAEKQIAWIAAGIPLNDKELSPLPLQTTILDVGDDPIAKIVGMRGGSREYRGTDHSFSDHYCRQIQAEQLWHDALPATDKPAVPPAPETSTETKPDAKSPKRVKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUS2</accession>
    <name>A0A518IUS2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Bifunctional protein PutA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">putA</name>
        <name evidence="9" type="ORF">Mal33_28420</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003842">
        <property type="term" value="F:1-pyrroline-5-carboxylate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004657">
        <property type="term" value="F:proline dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010133">
        <property type="term" value="P:proline catabolic process to glutamate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025703">
        <property type="entry name" value="Bifunct_PutA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029041">
        <property type="entry name" value="FAD-linked_oxidoreductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002872">
        <property type="entry name" value="Proline_DH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01619">
        <property type="entry name" value="Pro_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000197">
        <property type="entry name" value="Bifunct_PutA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51730">
        <property type="entry name" value="SSF51730"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pro_dh" evidence="8">
        <location>
            <begin position="161"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="domain" description="Aldedh" evidence="7">
        <location>
            <begin position="567"/>
            <end position="1007"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="492"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="active site" evidence="2 3">
        <location>
            <position position="783"/>
        </location>
    </feature>
    <feature type="active site" evidence="2 4">
        <location>
            <position position="817"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000197-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV56841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1242" mass="138020" checksum="0D7558BD3704D376" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IV14</accession>
    <name>A0A518IV14_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glucans biosynthesis protein G</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">mdoG</name>
        <name evidence="4" type="ORF">Mal33_29240</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Periplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016051">
        <property type="term" value="P:carbohydrate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014438">
        <property type="entry name" value="Glucan_biosyn_MdoG/MdoD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007444">
        <property type="entry name" value="Glucan_biosyn_MdoG_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30504">
        <property type="entry name" value="PTHR30504"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04349">
        <property type="entry name" value="MdoG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006281">
        <property type="entry name" value="MdoG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="SSF74650"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022092151" evidence="2">
        <location>
            <begin position="24"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="domain" description="MdoG" evidence="3">
        <location>
            <begin position="37"/>
            <end position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV56923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="525" mass="58718" checksum="F8CAFFDEB50C33D3" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IV66</accession>
    <name>A0A518IV66_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Periplasmic chaperone</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_29880</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Skp family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005632">
        <property type="entry name" value="Chaperone_Skp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024930">
        <property type="entry name" value="Skp_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03938">
        <property type="entry name" value="OmpH"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="OmpH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111384">
        <property type="entry name" value="SSF111384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
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    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022004006" evidence="4">
        <location>
            <begin position="25"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="46"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV56987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="195" mass="21786" checksum="7E82D7E12F90B8BF" modified="2019-10-16" version="1" precursor="true">MRITKATTIILGTLLSIAMVPALASAQQAAGGKIAVIDVAYIFKNSDAIKSEVAQIENSMKAYEQEMANVRKSMQKEAELLKTYKPGSPEYAGQEEKLAGMESKVKLETIRKRKELADAEARIYFDNYQKIRAVVKQVSEYNGIDLVLRYNSEEMELEKQDSVLRGVMKGVVYHSPKLDLTQMVMQAMGTKVATR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IV85</accession>
    <name>A0A518IV85_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_30000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetia</taxon>
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            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="266" mass="30052" checksum="C9EAC411111D6565" modified="2019-10-16" version="1">MTTSSESIRASELQEWLVFGELEERSKAMFSNSLLETGSLQRAAKETERFLEGDAVFEIDDDGSFEAMVSARCGLRYFSGVDAERASNIAHATCRALDNQIKRAYDTLPPREALHTIDNVWNMVEKTCELAAARSRLLLSKLPKLESVKLPTWFEDSVSRWDNDDREMLNPGSLDAARKIVCCVAAEFPGLTARVSVGILGRVTLDWYMNDLRCCWMIEPTDLPFPATRVYEARQEPHGKMQTRIIHDMHSVINALRDSAKESNDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IV87</accession>
    <name>A0A518IV87_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Multidrug resistance protein MdtA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">mdtA_2</name>
        <name evidence="4" type="ORF">Mal33_30040</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="domain" description="HlyD_D23" evidence="3">
        <location>
            <begin position="126"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV57003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="507" mass="56562" checksum="FFDC8C04AE9B376A" modified="2019-10-16" version="1">MKFRIPQSKKLAQWAWLGGLSLVVLVAGFTWQRWFPATQSWVGRTVAVFRSGGPESEHEGESAADPHAGHDHSGHAHAGHDEASSLELSAQAIRNIGLSDETIQPIRLETYRKSITVPAVVVERPGRSRVQVATPMTGVVTHVHAVQGEAIEPGALLFQVRLTHEDLVQAQTEFVQTLGEWDVEKREIARLQDVTRSGAVAGKVLLEREYAKDKLEAALSAQRESLRLHGLSDKQVEQIASERRLLRELQIYAPSVDNHPEEELRLSMNPIQAAAYTHNRQAAQPADGLPAVAGPLILQELAVHKGQSVSAGETLCILAEYDELFIEGLAFEQDIDQLRRASQNDWTVDAVFDQPNDKKQIVAGLRIVYLDNRVDPDSRTLNFYVRLTNQVTKDQRADGNRYIEWRYLPGQRLQLRVPVEEWPQQIVLPVEAVAREGAEFFVFQQNGNHFDRIPVHVKYRDQYSAVIDNDGSLFPGDVVAMRGAHQMQMALKNKAGGGVDPHAGHNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVC9</accession>
    <name>A0A518IVC9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_30360</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="87" mass="9519" checksum="9D35A36B2D8CA2A7" modified="2019-10-16" version="1">MGTRLNKIPNAPPHSFNRVGNAPRVQAQDQPKTRGPMGTRLNEIPNARLTRLTARATPRASSHQTDKNARPDGHAVKQNPQRPAALV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVM4</accession>
    <name>A0A518IVM4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_31390</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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    <dbReference type="InterPro" id="IPR017039">
        <property type="entry name" value="Virul_fac_BrkB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30213">
        <property type="entry name" value="PTHR30213"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03631">
        <property type="entry name" value="Virul_fac_BrkB"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="yihY_not_rbn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="99"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
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            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
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            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
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            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="294"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="326"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV57138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="379" mass="41245" checksum="53B1685CEEECF06C" modified="2019-10-16" version="1">MFRQPASNRAAAATGRDLRSTSLALAYKLRSKMPEVLPGGERPIRFAALPRTMSWHVGILQCRDRRRGDQSIGWRVFKVIKKTFTGFVDDQCTTLSAALAYYTIFALPPVLYLLLTVLVFGFSLAYTDGEAETEARMLLEDQAAQLLGNEAATEQITSILQRESDAGGHWWKTLLSFAGILVGATGVVGAIQSSLNRVWSVRPDPARSSMKTVVVKRLLSLAMILGLGFLLLVSLVVSTILSAIGARLSSVFGMDEVFARGINDGVQFVVTFVIFAAVFKFMPDAKVLWRDVAVGAFITTLLFLAGRFGLQWYLSNSDPGAQLGSAAASLVVILVWVYYSSMIFLLGAEATQAFASVYGGGIQPDRHAVRVVESIQRTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
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    <name>A0A518IVP0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_31570</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetia</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008930">
        <property type="entry name" value="Terpenoid_cyclase/PrenylTrfase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48239">
        <property type="entry name" value="SSF48239"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="157"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="679" mass="74417" checksum="8317A07CF13C5B8C" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVR7</accession>
    <name>A0A518IVR7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_31880</name>
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    <organism evidence="1 2">
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            <taxon>Planctomycetia</taxon>
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    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="818" mass="89127" checksum="095D1116091F423E" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVS9</accession>
    <name>A0A518IVS9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ammonium transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">amtB</name>
        <name evidence="10" type="ORF">Mal33_31850</name>
    </gene>
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        <name type="scientific">Rosistilla oblonga</name>
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            <taxon>Planctomycetia</taxon>
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            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the ammonia transporter channel (TC 1.A.11.2) family.</text>
    </comment>
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        <property type="protein sequence ID" value="QDV57184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008519">
        <property type="term" value="F:ammonium transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029020">
        <property type="entry name" value="Ammonium/urea_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001905">
        <property type="entry name" value="Ammonium_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018047">
        <property type="entry name" value="Ammonium_transpt_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024041">
        <property type="entry name" value="NH4_transpt_AmtB-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43029">
        <property type="entry name" value="PTHR43029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00909">
        <property type="entry name" value="Ammonium_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00836">
        <property type="entry name" value="amt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01219">
        <property type="entry name" value="AMMONIUM_TRANSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0924">Ammonia transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="57"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="90"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="163"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="189"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="230"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="264"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="294"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="327"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="351"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="380"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="423"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="domain" description="Ammonium_transp" evidence="9">
        <location>
            <begin position="57"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV57184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="479" mass="50477" checksum="69854FDD894EA1E0" modified="2019-10-16" version="1">MIRFPQQILCFLMLSCVATICVGQEAVPPPDTTAYSTATLDEMQASIDAAALAGHNAWMLTSCALVLFMTAPGLALFYGGLVRRKNVLSVMMQCIFLMGLMTVIWSLYGYSLAFGGTPGESYLSHLIGNGEYLMMNNVSRTWDEAAGAPFTPMEGEIPRLTHMLFQGMFFIITPALICGAFAERMKFSAMVVYSVLWGTFIYCPLAHWVWDGGILAYDGDQAVLGGALDFAGGTVVHISSGVSALVAAIMIGPRMGFGKLPLPPHNLTFTAVGSAMLWFGWFGFNAGSELASDALTSSAFAVTHFSAAAGAVAWAACEWLLRGKPTVLGACSGAVAGLVCITPAAGFVNPMPALIMGAIAGVACYWSCAKLKHIFRYDDALDAFGVHGVGGTVGAVLTGLFATRACWDIGEGAKLGLFEGGNVLAGQVAAVVVTYVYAGIGSIVLLLLIKMTIGLRVEANDEEQGLDISLHGEEAYVLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IW30</accession>
    <name>A0A518IW30_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Inositol 2-dehydrogenase</fullName>
            <ecNumber evidence="8">1.1.1.18</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">iolG_8</name>
        <name evidence="8" type="ORF">Mal33_32930</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.18" evidence="8"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016798">
        <property type="term" value="F:hydrolase activity, acting on glycosyl bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050112">
        <property type="term" value="F:inositol 2-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008152">
        <property type="term" value="P:metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043906">
        <property type="entry name" value="Gfo/Idh/MocA_OxRdtase_bact_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019546">
        <property type="entry name" value="TAT_signal_bac_arc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19051">
        <property type="entry name" value="GFO_IDH_MocA_C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01409">
        <property type="entry name" value="TAT_signal_seq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0520">NAD</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GFO_IDH_MocA" evidence="6">
        <location>
            <begin position="48"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="GFO_IDH_MocA_C2" evidence="7">
        <location>
            <begin position="220"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="GFO_IDH_MocA_C2" evidence="7">
        <location>
            <begin position="362"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF19051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV57289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="434" mass="47847" checksum="A7FE84063331ECB0" modified="2019-10-16" version="1">MQSSPENSRRQFLKRSAATSALAVAAPLVVAPHVLGKTRVAPSDKISLGVIGIGPRCRYDLKSMLSLDDVQCVALADVQQSRRVEGKKFIDGHYGNDDCAVYDDFRELLSRDDIDTVIVATGDRWHASASMLAAEAGKDVYSEKPCGITIELCQQLAETMKRTGRVFQAGTQRRSVPNFQQAVQLAQSGALGKLHTLYASVYIPSLDNSWLPGEPTPDRETCDWNMWLGPAPWRPYNSKYVSGGWRGYHDFDSGARLLDWGAHTVDLCQMANGSDDTLPVEYTPSETNITCRYANGVKLVIDFLKDPFGDRGPKWITRLGTCPVRFVGSEGSVETGDSGEIVVKPADLQTRVGDYKRVVGLDVTAHARDFFDCVKSRKAPVANGEVMRRSHVACHAAALAWILQRKLTLDPKTEAFIGDDEANRLRSRPARDWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IW95</accession>
    <name>A0A518IW95_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 9">Quinolinate synthase</fullName>
            <ecNumber evidence="2 9">2.5.1.72</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9 10" type="primary">nadA</name>
        <name evidence="10" type="ORF">Mal33_33670</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>dihydroxyacetone phosphate + iminosuccinate = H(+) + 2 H2O + phosphate + quinolinate</text>
            <dbReference type="Rhea" id="RHEA:25888"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29959"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:77875"/>
            <dbReference type="EC" id="2.5.1.72"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="9">Binds 1 [4Fe-4S] cluster per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 9">Cofactor biosynthesis; NAD(+) biosynthesis; quinolinate from iminoaspartate: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the quinolinate synthase family. Type 3 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.72" evidence="2 9"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00327"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008987">
        <property type="term" value="F:quinolinate synthetase A activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10800">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00569">
        <property type="entry name" value="NadA_type3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003473">
        <property type="entry name" value="NadA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036094">
        <property type="entry name" value="NadA_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023515">
        <property type="entry name" value="Quinolinate_synth_A_type3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30573">
        <property type="entry name" value="PTHR30573"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02445">
        <property type="entry name" value="NadA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142754">
        <property type="entry name" value="SSF142754"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00550">
        <property type="entry name" value="nadA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 9" id="KW-0408">Iron</keyword>
    <keyword evidence="8 9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="6 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 9" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9 10" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Iminoaspartate binding" evidence="9">
        <location>
            <begin position="150"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Iminoaspartate binding" evidence="9">
        <location>
            <begin position="267"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="44"/>
        </location>
        <ligand>
            <name>iminosuccinate</name>
            <dbReference type="ChEBI" id="CHEBI:77875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>iminosuccinate</name>
            <dbReference type="ChEBI" id="CHEBI:77875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>iminosuccinate</name>
            <dbReference type="ChEBI" id="CHEBI:77875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="241"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="284"/>
        </location>
        <ligand>
            <name>iminosuccinate</name>
            <dbReference type="ChEBI" id="CHEBI:77875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="331"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV57362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="379" mass="42316" checksum="B22A921EFA86863C" modified="2019-10-16" version="1">MSVSIQPSEALPLKPYKSLSNTELSQRIQTVRQQLGDSLLILGHHYQQDEVIEHSDLRGDSYQLSQMAAESAACKTIVFCGVHFMAETADILANRPEKLEQRDGQRVSVILPDMAAGCSMADMAAIDQVENAWADMGEVIDTKSVIPVTYINSAASLKAFCGKHGGIVCTSSNARAVLEWAFERGQRVFFFPDQHLGRNTALTMDITNDQMPVWDPYEDELGGNDEQAIRNSKVILWKGHCSVHQMFRPEHVDAFRKNHPGIKILVHPECPQDVNDLADVSGSTGKIINTVKESPAGTKWAIGTELHLVNRLKQEHPEQEIHFLSPVICMCATMYRIDLAHLCWCLENLVAKENVNVIEVDEETSRWSLVALERMLAVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWL9</accession>
    <name>A0A518IWL9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Na(+)/H(+) antiporter NhaA</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Sodium/proton antiporter NhaA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">nhaA_1</name>
        <name evidence="7" type="synonym">nhaA</name>
        <name evidence="9" type="ORF">Mal33_35020</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>2 H(+)(out) + Na(+)(in) = 2 H(+)(in) + Na(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:29251"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015081">
        <property type="term" value="F:sodium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006885">
        <property type="term" value="P:regulation of pH"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01844">
        <property type="entry name" value="NhaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023171">
        <property type="entry name" value="Na/H_antiporter_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004670">
        <property type="entry name" value="NhaA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30341">
        <property type="entry name" value="PTHR30341"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06965">
        <property type="entry name" value="Na_H_antiport_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00773">
        <property type="entry name" value="NhaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0050">Antiport</keyword>
    <keyword evidence="3 7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0915">Sodium</keyword>
    <keyword evidence="7" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="34"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="91"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="120"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="154"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="180"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="209"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="326"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="353"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="388"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="427"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV57492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="454" mass="48820" checksum="A0951C8A1DDD5EA7" modified="2019-10-16" version="1">MHVQLPVDHSGSDSENQSGPLLPRRPIDRLARPLARFLHIEATSGIVLMICTAVAIGLANSPWAETYLGFWKTKVNLQFGSFQFEHSLQHIINDGLMALFFFVIGLEVKRELVHGSLSDIRRATLPIAAALGGMIVPAGIYLSMQYGQPAVRGWGIPMATDIAFVVGCLALLGSRVPNSLRVLLLSLAIVDDIGAIIVIAIGYTDHLDVRFLGMAAVVIGVVQLFSYLGVRRFPPYIVAGMIAWYAFHESGVHATLAGVILGLMTPAKASIVPERFRVYLNQTSKSYEADESDVRVRRGEQVRMLQRISRETISPLEYLETALHQWSSYLVIPIFALANAGVAFQLSNVNDPVALAVILGLVVGKPLGVLAFSLLAVKSGLARLPEGLNWSVLAAGSFLAGIGFTMALFIEGLAFGGDSFNNAKTGILVGSGVSAVLGMTFLLWTLPKPTAQSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWS5</accession>
    <name>A0A518IWS5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Arylsulfatase</fullName>
            <ecNumber evidence="6">3.1.6.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">atsA_26</name>
        <name evidence="6" type="ORF">Mal33_35260</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="PTM">
        <text evidence="3">The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the sulfatase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.6.1" evidence="6"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004065">
        <property type="term" value="F:arylsulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024607">
        <property type="entry name" value="Sulfatase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00149">
        <property type="entry name" value="SULFATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sulfatase" evidence="5">
        <location>
            <begin position="30"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="343"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="modified residue" description="3-oxoalanine (Cys)" evidence="3">
        <location>
            <position position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR600917-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV57516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="568" mass="63935" checksum="BD5B96690B4062E0" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWU0</accession>
    <name>A0A518IWU0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Pyrrolidone-carboxylate peptidase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">5-oxoprolyl-peptidase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Pyroglutamyl-peptidase I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">pcp</name>
        <name evidence="9" type="ORF">Mal33_35720</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C15 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016920">
        <property type="term" value="F:pyroglutamyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00501">
        <property type="entry name" value="Peptidase_C15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000816">
        <property type="entry name" value="Peptidase_C15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016125">
        <property type="entry name" value="Peptidase_C15-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036440">
        <property type="entry name" value="Peptidase_C15-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23402">
        <property type="entry name" value="PTHR23402"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01470">
        <property type="entry name" value="Peptidase_C15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015592">
        <property type="entry name" value="Prld-crbxl_pptds"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00706">
        <property type="entry name" value="PYROGLUPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53182">
        <property type="entry name" value="SSF53182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0788">Thiol protease</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00030836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV57562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="195" mass="21698" checksum="79F5E60243A05FB8" modified="2019-10-16" version="1">MPRVLLTAFEPYEEWRENSSWLTLIELTRWFDGGDDVVTRRYPVDFQAVKHRLAIDMQQDFDLILHLGQAPGASVIRLESFAVNMGSNHCELVDGGPAAYKSPLPLTAWGKKLHDRGVPAQVSYHAGTYLCNATLYMSHHYAACEGLQTQSTFLHLPVAPNQVAARQKPMPSMSVPLMAAGVAMLLEEFLQRSSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWX6</accession>
    <name>A0A518IWX6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peptidase family M50</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_35980</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001193">
        <property type="entry name" value="MBTPS2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13325">
        <property type="entry name" value="PTHR13325"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="151"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="189"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="228"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="255"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="285"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="359"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="387"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="427"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="713" mass="79178" checksum="D79D7A1CCB053D58" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IX51</accession>
    <name>A0A518IX51_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_36780</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="110" mass="11717" checksum="BAD4B94A6164C6AA" modified="2019-10-16" version="1">MASTITEYLKENPEITWKAAAETLEPKGISESYFSNQKSKLRKEGILPSSGRKKAGRKPAAAKSATAKKPVAKKSAVVGGELASAAEFARTAGGLDEARRLLDQLSEVQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IX77</accession>
    <name>A0A518IX77_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphodiesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_36990</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallophosphoesterase superfamily. YfcE family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024654">
        <property type="entry name" value="Calcineurin-like_PHP_lpxH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011152">
        <property type="entry name" value="Pesterase_MJ0912"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12850">
        <property type="entry name" value="Metallophos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000883">
        <property type="entry name" value="Pesterase_MJ0912"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos_2" evidence="2">
        <location>
            <begin position="5"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="249" mass="28099" checksum="6C6EA972D8B0E2AD" modified="2019-10-16" version="1">MPRQAIVSDIHGNLVALQAVLADIAEQNVDSIACLGDVVGYGPQPCECLDVVAGFEFTILGNHDLSALFDPEGFNAAAEQAIFWTRRQLENGTDKEASRRRLDLLCNLPRTYRRGGMLYVHGSARGPTTEYVFPEDTYNPRKMEKIFSMVPEVCFQGHTHVPGVFTHENQFVRPDETGHVYELSGKKAMVNVGSVGQPRDGDPRSCYVIVEDRRLEFRRVEYDIEKTVRMIEAEADLDNFLGYRLREGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXB7</accession>
    <name>A0A518IXB7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF4129 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_37450</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025403">
        <property type="entry name" value="DUF4129"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13559">
        <property type="entry name" value="DUF4129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="141"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4129" evidence="3">
        <location>
            <begin position="231"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="171"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV57732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="309" mass="34532" checksum="CF8048EF9ACA7D44" modified="2019-10-16" version="1">MTCHRDSAIDRTASCRFAATQFEDRCGDCRAAIRCSLMLLCQLLLWLIGLPSPTLADSPASPAAAEASDSSDAIGRSALESLGNVPWFDRDEDRVKAVPVEKTDAADDDVAARTVGYEAAKKPNTQGTGNYQSVLEMIGQVISWSILAVLVLLIVAAIAYAFMLHERDRAPRRAATAERGDRESETAERLQRLPVQIDQPASNLLSEARRLMEAGRYNEAIVYLFSHELVQLDRHQLLRLARGKTNRQYLREIRQSYDLQEILHNTIHAFEDAFFGDHTLTRQRFQSCWEQLDRFHAAVEQTAGKGASV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXS9</accession>
    <name>A0A518IXS9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_39040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010985">
        <property type="entry name" value="Ribbon_hlx_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014795">
        <property type="entry name" value="Vibrio_phage_ICP1_Orf50"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35401">
        <property type="entry name" value="PTHR35401"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08681">
        <property type="entry name" value="DUF1778"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47598">
        <property type="entry name" value="SSF47598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="92" mass="10119" checksum="9ADAA7CB6BC7D312" modified="2019-10-16" version="1">MATTKNDARINVRLASELKQVIEEAATALGQSVSEFTVSTVVREARQVIQEAQFTRLSTRDRDAFLGALRAADAKPNDALKAAARRYKKRVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXU2</accession>
    <name>A0A518IXU2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">N-acetylglucosamine repressor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">nagC</name>
        <name evidence="3" type="ORF">Mal33_39110</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ROK (NagC/XylR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000600">
        <property type="entry name" value="ROK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18964">
        <property type="entry name" value="PTHR18964"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12802">
        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00480">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="2">
        <location>
            <begin position="16"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="392" mass="42718" checksum="D9550F666D577A09" modified="2019-10-16" version="1">MNVSHSTQPKLLSQLNERAVLRVLQTNGPSSRAEVTRLAGVTRPTVSKAVSSLLKSGFLEEFDAPENNRGRPAKLLRLGGATSQVVGLVIDSPVCRIVTAGLDGSLRSDVYREFKTPETYDELIAIITDQIETLSSARDLRTLGVGVSMPGLYDYKEGCSILSPNVPLTNGHCLGRDLSQRLNMEVTVLQESDALCLAERHFGLASRMTDFAMLDASTGIGLGILNDGRLLKGSCGLAGELGHLPMVRDGIQCGCGRTGCLETLASDTAFTRRVSQKQSRDLTFTQIAERVAAGKLCVAEELEQVLEHLVFALVTTINLFNPQTLFVHSRMFDLDDRLLERLIRQTESRALQPSFRQCRIQRARGSKREGAVAGIIEYLTHSRVSPLAPVGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IY58</accession>
    <name>A0A518IY58_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">3-oxoacyl-[acyl-carrier-protein] synthase 2</fullName>
            <ecNumber evidence="4">2.3.1.179</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">fabF_5</name>
        <name evidence="4" type="ORF">Mal33_40390</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.179" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00834">
        <property type="entry name" value="KAS_I_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000794">
        <property type="entry name" value="Beta-ketoacyl_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11712">
        <property type="entry name" value="PTHR11712"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PKS_KS" evidence="3">
        <location>
            <begin position="5"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV58023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="437" mass="46256" checksum="7F1B62F7942732F0" modified="2019-10-16" version="1">MYRRVVITGMGVVTPLGHQLDNFWQNLTSGRSGVGPISTFDASNFPVRIAAEVPSSWSLESVGENPRQWAGAPRQSSFALAAGISAVRDSGIELDRFDPLLSGVYLGCGEPFTPFAPLVGSISQAMADQKFNSAAFTDTALRLFDPKSQRQFDPKMPAISLAARFNLQGPSVNCIAACVSSSQAIGQAVRMIRRGEVNTMLCGGAHSCVNELGVTGFSRLSALSQQNDSPTQASRPFDRNRDGFVIGEGGAVFVAEEYEQARRRGAHIYAEVTGYGSAQDAFRVTDTHPQGRGSVQAISRALKDAGIDGGDLSYINAHGTGTVLNDKVETHSIKTALGSAAYDVPVSSSKSMLGHATTACGAIELAVALLAMQSNTLPPTINFDDPDPACDLDYVPNVARDVQCQHILSNNIGFGGQNAALIVSRVSEPRTCCQHAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IY95</accession>
    <name>A0A518IY95_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_40690</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011453">
        <property type="entry name" value="DUF1559"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07596">
        <property type="entry name" value="SBP_bac_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="337" mass="36055" checksum="9DA7C5E83D33AB27" modified="2019-10-16" version="1">MHRQKPKSAFTLVELLVVIAIIGILVGLLLPAVQAAREAARRMQCGNNLKQLGLALHNYHDTFKTFPPALLGSGRYNNASYHAAHGGIKNTTGWALLLPFFEQSTIADKYDYDVCSSSSSPYGGVVAGDDSINDGLYNTRIDVLECPSDPSAGRVISVGAGTTDFYSRRDAIQTSYLFSTGGFTDYSAPWESYSADIRQGVFGNDGAARFASMSDGTSTTIAIGEATGGPFKTSTSYGPWGLTGTHTSCHGYIPGGSSTVLTQAYAASYTQNWSINGAYNNDSLGRTYAWVFGSKHPGGASFVFSDGSVHLLTETINYMTLQQLAYIRDGQPVPSDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYA5</accession>
    <name>A0A518IYA5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Sensor histidine kinase YycG</fullName>
            <ecNumber evidence="5">2.7.13.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">yycG</name>
        <name evidence="5" type="ORF">Mal33_40860</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.13.3" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="35"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="4">
        <location>
            <begin position="117"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="3">
        <location>
            <begin position="237"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV58069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="466" mass="51699" checksum="67780E05C785C633" modified="2019-10-16" version="1">MLRALWKALLIAGLIGLLLGGITIASVPLEYRSQLAIRFAVAYGVIATLVSIWLVQRSTRHTKAESDLMWWANDLANGDLASRVRTPMFSGEQAQLLQHLNRLQESTRGQIEQLQADRRRSFMVLAHMVEGIVAIDDERRVLLVNEAACRFLKLNKETAVGRKLLEVIRVPEVTNLVNQTLSTNEDSEVELQSTDMRQLLVKSSTLPSESRRGVLLTIHDQTQLKQLEAMRREFVANVSHELKTPLAAVKGYAETLQLGAIDDKEIAPHFVDQILSQADRLERLIADMMHLARAQDRSQPAAPVDVLVFPVIQECCETYQPVAAQKEIELILEPFDEACTILGEREALLTVVNNLVGNALRYTQVGGHVRVSCQPGEEQVSIAVTDDGLGIPHEDQERIFERFYRVEKARDQQYGGTGLGLAIVKNIVQSFGGSMRLQSEPGKGSTFEAVLPCSPATVPLQTAKSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYC9</accession>
    <name>A0A518IYC9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_41050</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="143" mass="14584" checksum="7488684B90BE6454" modified="2019-10-16" version="1">MRNTAARCCANVTWIMALHVTLTTLGCGSDTGGRVDVSGKVTLGGAPLESGTIEIVAADGSSQSGATVTNGEFSIPAERGLKPGDYIVKIFAGDETVAAVEAAPGDSSAAPVSKERIPPEYNVESTLTAKIEASDNVLSFDIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYT8</accession>
    <name>A0A518IYT8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Universal stress protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_42740</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal stress protein A family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006015">
        <property type="entry name" value="Universal_stress_UspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01438">
        <property type="entry name" value="UNVRSLSTRESS"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Usp" evidence="2">
        <location>
            <begin position="2"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="Usp" evidence="2">
        <location>
            <begin position="152"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="302" mass="33363" checksum="031470F066FD2B34" modified="2019-10-16" version="1">MRVLLASDRSESSDAAAEYLHQLQFSEPIELNVLSSVPVTASVGFSGLPAVVQSVMQEEEVALRKHLDAVCSRFENRTASTVSNLVVGPPGYEIRSEADKWNADLIVMGAVGKSMMERVVLGSVSDFVATHTASSVLVVRPPKPEAAEQPPRRIMVALDGSKDDTQLIDLLRAIQWPADAELHLVHVIEDLTLYRQDLIEHMDQHWQQERDTSQQHADEILKLAEGTIDNIQTAILVDGHTGEALVKYADRHQCDLIIAGDHHRNILNRILLGSVSRYVLRYAHCSVAIARRKEADEAAATT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYV6</accession>
    <name>A0A518IYV6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Tetratricopeptide repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_42930</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="224" mass="25275" checksum="C496AAF9E76A88F8" modified="2019-10-16" version="1">MSQPATRTSRIVNQYRRYLDASDSLDFFRTVNESYTVDTLLTLLRRGDSESRRASALALSMVGDVRATEALGHRLSDRDRGVRLIADDAFRAILVRDAAPSHHQNLLQVMHLNDGGEFAAALTPAMVLVQQAPRYAEAHHQLAIAYLGLQEYASADCAFRNCLWHCRFHYLAWSGLADCRRAIGDQREALKHLHRAIAICPDFESARIQARAIRRSLNRNPPTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYX7</accession>
    <name>A0A518IYX7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">AP2 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Mal33_43090</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006334">
        <property type="term" value="P:nucleosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001471">
        <property type="entry name" value="AP2/ERF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005819">
        <property type="entry name" value="H1/H5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00847">
        <property type="entry name" value="AP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00624">
        <property type="entry name" value="HISTONEH5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="AP2/ERF" evidence="5">
        <location>
            <begin position="79"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="163"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV58291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="246" mass="27137" checksum="598DA884D0A8A555" modified="2019-10-16" version="1">MNLTRMDHEGCRGWWVRIQRGDQHVSKLFSDGVYGSTRKAEIAATKFRDEQLKELPARVFKGSKGPRLNAAGYYLRTRVRRGKDEQAWVAIWTEDGRQLEKSFSINQHGNAAAKKLAKAYRQEMVEKLIGGGGETKATKNAPVKKKAAVKKTTTKKAAAKKSVKKAPVKKTAKKKAAVKKTAVKKSPVKKATKKAAVKKKAAVKKAAVKKKAPVKKTATKKAPVKKVAKKAAVKKKVAKKKATKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYZ3</accession>
    <name>A0A518IYZ3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">p-hydroxybenzoic acid efflux subunit AaeA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_43150</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="167"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="333" mass="36966" checksum="84E7B39A56EA2472" modified="2019-10-16" version="1">MQQHLFNLKRRLINIRETQHIHAPSQPQSLPKRTAFFKLSFGLLGFAVAFASQPANAQPTSTLIVVEDCAVRFAEEIRVPAVEAGRVVEVKVKLNDTVAAGHSIARQDDAAALLRRRAAVWQQTAAREETSDEVDLDYAKALYAEAVAQRDADKGIYQKGGGSLRTVRQSELGVERARLEIARAEKALRLAQIQYELRSAELSAIDDQLERLQIKSPIAGVILSIERRAGEWIKEGETIATVARMDQLRIDAFLSAQQLPQQQAVGSPVSVVWQNAGQTHQLSGVIDSVDPQILTGQRYRLHATIDNKRLGNSWLLLPGTEVEMRVHPPQRGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ22</accession>
    <name>A0A518IZ22_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_43520</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="103" mass="10920" checksum="1F9F1B04BAD4252A" modified="2019-10-16" version="1">MTIQPSAAVTGLAGTARAQQRGSDTETVNNQQAALNQSQSPGQAEGADQLTLEASGKTGDRDGDGRRPFELQEREHTEDDEADVESVGKAVDDDQGEHLDLEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ59</accession>
    <name>A0A518IZ59_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="12 13">DNA primase</fullName>
            <ecNumber evidence="12">2.7.7.101</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12 17" type="primary">dnaG</name>
        <name evidence="17" type="ORF">Mal33_43900</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12 13">RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12 13 14">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="12 13 14">Binds 1 zinc ion per monomer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Monomer. Interacts with DnaB.</text>
    </comment>
    <comment type="domain">
        <text evidence="12">Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.</text>
    </comment>
    <comment type="similarity">
        <text evidence="12 13">Belongs to the DnaG primase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.101" evidence="12"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990077">
        <property type="term" value="C:primosome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003896">
        <property type="term" value="F:DNA primase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03364">
        <property type="entry name" value="TOPRIM_DnaG_primases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.980.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00974">
        <property type="entry name" value="DNA_primase_DnaG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013264">
        <property type="entry name" value="DNA_primase_core_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037068">
        <property type="entry name" value="DNA_primase_core_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006295">
        <property type="entry name" value="DNA_primase_DnaG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036977">
        <property type="entry name" value="DNA_primase_Znf_CHC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030846">
        <property type="entry name" value="DnaG_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034151">
        <property type="entry name" value="TOPRIM_DnaG_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002694">
        <property type="entry name" value="Znf_CHC2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08275">
        <property type="entry name" value="Toprim_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01807">
        <property type="entry name" value="zf-CHC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002811">
        <property type="entry name" value="DnaG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00493">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00400">
        <property type="entry name" value="ZnF_CHCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01391">
        <property type="entry name" value="dnaG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 12 13" id="KW-0235">DNA replication</keyword>
    <keyword evidence="10 12" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1 12 13" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 12 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 12 13" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="2 12 13" id="KW-0639">Primosome</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 12 13" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 12 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 12 13" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 12 14" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Toprim" evidence="16">
        <location>
            <begin position="264"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="CHC2-type" evidence="12 14">
        <location>
            <begin position="40"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="430"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="432"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRNR" id="PIRNR002811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR002811-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="QDV58372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="617" mass="69059" checksum="8E8D9A8A1BF43DE9" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ93</accession>
    <name>A0A518IZ93_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Membrane protein YdgH</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ydgH</name>
        <name evidence="8" type="ORF">Mal33_44250</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004869">
        <property type="entry name" value="MMPL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03176">
        <property type="entry name" value="MMPL"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="310"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="334"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="376"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="417"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="449"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="824"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="848"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="883"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="922"/>
            <end position="948"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="968"/>
            <end position="990"/>
        </location>
    </feature>
    <feature type="domain" description="MMPL" evidence="7">
        <location>
            <begin position="262"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="domain" description="MMPL" evidence="7">
        <location>
            <begin position="795"/>
            <end position="947"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV58407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1008" mass="111893" checksum="E1FCD9D5C138A255" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZF1</accession>
    <name>A0A518IZF1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Arsenical pump-driving ATPase</fullName>
            <ecNumber evidence="3">3.6.3.16</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">arsA</name>
        <name evidence="3" type="ORF">Mal33_44960</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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            <begin position="7"/>
            <end position="226"/>
        </location>
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            <begin position="327"/>
            <end position="521"/>
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    <feature type="region of interest" description="Disordered" evidence="1">
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            <begin position="579"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
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            <begin position="581"/>
            <end position="598"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="598" mass="63478" checksum="81A74F94B6393488" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
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            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
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    </dbReference>
    <proteinExistence type="predicted"/>
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            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
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        <location>
            <begin position="62"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
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            <begin position="64"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="101" mass="11162" checksum="8F6302A75B01EF40" modified="2019-10-16" version="1">MPTYDYECDACGHEFEHFQGINDPHLKKCPECKKLKLRRLFGTGAAVVFKGSGFYQTDYRSESYKKGAAADKKSSKSSSDSKSSDKKPAAKSESKPKKAAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
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    <name>A0A518IZF4_9BACT</name>
    <protein>
        <submittedName>
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
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                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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        <property type="entry name" value="DUF3467"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11950">
        <property type="entry name" value="DUF3467"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="175"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="214" mass="23194" checksum="8D6FFF83F87397EA" modified="2019-10-16" version="1">MNDTPSEGQPAPGESGQNLRARIPDHVGEGVFSTGAIVVTGPTEFVLDFVQNISRPHRVATRVILPHPVLPQFLDALRKNLEIYKGRFGAPADPPKPPADARRPTPQEIYDDLKMSDAILSGAYANGVMIGHGAAEFSLDFITSFFPQSAVSARVYMAAGQIPRLIESLDNAMKQLQMRTGQLPPPKQNPPSTQSPGDDLLPPNENRPDPEEPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
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    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Boedeker C."/>
                <person name="Pinto D."/>
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                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
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                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
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                <person name="Spormann A.M."/>
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                <person name="Overmann J."/>
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                <person name="Mascher T."/>
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                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="component" value="Chromosome"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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    </dbReference>
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        <property type="entry name" value="Class_I_gatase-like"/>
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        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="927" mass="102336" checksum="F7B53C1A5893ECB0" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZQ5</accession>
    <name>A0A518IZQ5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hemin uptake protein hemP</fullName>
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    <organism evidence="2 3">
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    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019600">
        <property type="entry name" value="Hemin_uptake_protein_HemP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10636">
        <property type="entry name" value="hemP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="63" mass="7201" checksum="204329B92856B1DC" modified="2019-10-16" version="1">MPDDNERFPPADPAEKPLGKSDDRPRMVSSSDLLCGRREVWIQHGDAVYRLRVTSADKLYLTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZU8</accession>
    <name>A0A518IZU8_9BACT</name>
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        <submittedName>
            <fullName evidence="14">Sensory/regulatory protein RpfC</fullName>
            <ecNumber evidence="14">2.7.13.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">rpfC_3</name>
        <name evidence="14" type="ORF">Mal33_46370</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="14"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000156">
        <property type="term" value="F:phosphorelay response regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008984">
        <property type="term" value="F:protein-glutamate methylesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902531">
        <property type="term" value="P:regulation of intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035909">
        <property type="entry name" value="CheB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022642">
        <property type="entry name" value="CheR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000780">
        <property type="entry name" value="CheR_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022641">
        <property type="entry name" value="CheR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000673">
        <property type="entry name" value="Sig_transdc_resp-reg_Me-estase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01339">
        <property type="entry name" value="CheB_methylest"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01739">
        <property type="entry name" value="CheR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03705">
        <property type="entry name" value="CheR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00996">
        <property type="entry name" value="CHERMTFRASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00138">
        <property type="entry name" value="MeTrc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52738">
        <property type="entry name" value="SSF52738"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50122">
        <property type="entry name" value="CHEB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50123">
        <property type="entry name" value="CHER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CheB-type methylesterase" evidence="12">
        <location>
            <begin position="12"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="CheR-type methyltransferase" evidence="13">
        <location>
            <begin position="208"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="10">
        <location>
            <begin position="1006"/>
            <end position="1077"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="11">
        <location>
            <begin position="1084"/>
            <end position="1135"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="10">
        <location>
            <begin position="1303"/>
            <end position="1375"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="11">
        <location>
            <begin position="1379"/>
            <end position="1432"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="10">
        <location>
            <begin position="1433"/>
            <end position="1507"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="11">
        <location>
            <begin position="1511"/>
            <end position="1561"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="8">
        <location>
            <begin position="1579"/>
            <end position="1799"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="9">
        <location>
            <begin position="1834"/>
            <end position="1953"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="472"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="632"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="5">
        <location>
            <position position="1888"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="QDV58613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1956" mass="218667" checksum="57E8E5FC2E5CB73B" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J002</accession>
    <name>A0A518J002_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_46760</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
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            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021944681" evidence="1">
        <location>
            <begin position="23"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="109" mass="12357" checksum="B0C69E40A74A812B" modified="2019-10-16" version="1" precursor="true">MKRITSIAMLAVVALASSHATAQDNELPAPGRIVLEESKPYSSQPQALTVAQLRQQIAMEKSRQRRARMEYNAWRGYSPLRPTASDMPMMRSSIVYPQYRVSFVPVYAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J011</accession>
    <name>A0A518J011_9BACT</name>
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            <fullName evidence="2">SHOCT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_47050</name>
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    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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        <property type="entry name" value="SHOCT"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
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        <location>
            <begin position="258"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="209"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="227"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="287" mass="30217" checksum="D608F5E8380A4AA4" modified="2019-10-16" version="1">MQNLSPAGIELVQRLSQQHGLSTDAVTHMLIAVQNGNGSMAQFNHPAFGGAGQWMRGGMTMVSDLFNHQLKNCVNNLCAEISDALNNHQLVPFSGSFQSQSQGGSGGQTQAAGQIGSANSLFVPDPSKNWWPQEMGSPNAIGSQNNVRYAYFANIHRLAVNTGGGTWVYDALNHQIGGFSQQQGSGGSITFTSQFGVVDLSTLPVISRDGVPAAPQQAPPASPPPSHTDHSSSQPSNPAPMPASHPSSNASGNDIIETLDRLGGLLEKGYISEQEFAAKKADLLSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J023</accession>
    <name>A0A518J023_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Recombinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_47180</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000150">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR038109">
        <property type="entry name" value="DNA_bind_recomb_sf"/>
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        <property type="entry name" value="DNA_bind_recombinase_dom"/>
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        <property type="entry name" value="Resolv_N"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="SSF53041"/>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="11"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="Recombinase" evidence="2">
        <location>
            <begin position="193"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="602" mass="68034" checksum="86B9D214120B06CD" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0B3</accession>
    <name>A0A518J0B3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Adenylate cyclase 2</fullName>
            <ecNumber evidence="2">4.6.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">cyaB</name>
        <name evidence="2" type="ORF">Mal33_48110</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="4.6.1.1" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009190">
        <property type="term" value="P:cyclic nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
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        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00044">
        <property type="entry name" value="CYCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Guanylate cyclase" evidence="1">
        <location>
            <begin position="361"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="613" mass="67324" checksum="DB8721515CF2E8B1" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0J2</accession>
    <name>A0A518J0J2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Isoaspartyl peptidase</fullName>
            <ecNumber evidence="5">3.4.19.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">iaaA</name>
        <name evidence="5" type="ORF">Mal33_48770</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.4.19.5" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008798">
        <property type="term" value="F:beta-aspartyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000246">
        <property type="entry name" value="Peptidase_T2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10188">
        <property type="entry name" value="PTHR10188"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01112">
        <property type="entry name" value="Asparaginase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="194"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="249"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="272"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="221"/>
        </location>
    </feature>
    <feature type="site" description="Cleavage; by autolysis" evidence="3">
        <location>
            <begin position="220"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR600246-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR600246-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR600246-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV58852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="357" mass="37954" checksum="316E22BF847F1D5D" modified="2019-10-16" version="1">MKRTVPTCLSLCIKAIGFLAVFLACGTLSAEKPRWAIALHAGAGSVSKDISAERLQEYKTSIRKALETGEAVLRSGGTALDAVERTVMVLEDAAGFNAGKGAVFNAEGFHQLDASIMDGNDLSCGAVAAVETIRNPIQAARLVMERTPHVLLVSKGAERLAKLHNIEIVTPDYFYDATRWQQLQKKLKATGRKELDNPCYPVPPEANQTGDRTDQEISRGTVGCVALDMHGNLAAGTSTGGLTGKMVGRVGDSPIIGAGTYADNRGCAISATGSGEEYIRHGIAAQVNWRMRFANQSLSEATQACINDVLKPGDGGVIAVDHDGNLSLEFNTTSMSRAWADSKGNSGIAIWEERFAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0Y2</accession>
    <name>A0A518J0Y2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">D-3-phosphoglycerate dehydrogenase</fullName>
            <ecNumber evidence="5">1.1.1.95</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">serA_2</name>
        <name evidence="5" type="ORF">Mal33_50220</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.95" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004617">
        <property type="term" value="F:phosphoglycerate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006139">
        <property type="entry name" value="D-isomer_2_OHA_DH_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029753">
        <property type="entry name" value="D-isomer_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00389">
        <property type="entry name" value="2-Hacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00671">
        <property type="entry name" value="D_2_HYDROXYACID_DH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2-Hacid_dh" evidence="3">
        <location>
            <begin position="4"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="domain" description="2-Hacid_dh_C" evidence="4">
        <location>
            <begin position="104"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV58997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="324" mass="35783" checksum="C12808E80D66CCEB" modified="2019-10-16" version="1">MRIVLCYPVEPHHIAQIQAAAPDFEVVDAGQERIDELLPTADIFIGHAKVPVDWDRVLKANRLRWIQSSAAGLDHCLVPGVIDSDIVVSSASGLFAPQVAEQTMTLLLDLIRSQGRFNRANSRHEFIRLPTDDLRQKKVGIVGLGGNGRRIAKVLKPFDVSIVATDYFSFDPPPEVDRLLPADAVDEMLAEVDIAILALPLNAQTRGMFDADRFAKMRPGSYFINVARGQVVVESALVDALDSGHLRGAGVDVTEVEPLPDKSPLWDRENVIITPHVGAQSRWRVDDTTVMVCENLRRFQAGESIYNTVDKQLGFPSPEVVWHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0Y5</accession>
    <name>A0A518J0Y5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA topoisomerase (ATP-hydrolyzing)</fullName>
            <ecNumber evidence="4">5.6.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">gyrB</name>
        <name evidence="7" type="ORF">Mal33_50170</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP-dependent breakage, passage and rejoining of double-stranded DNA.</text>
            <dbReference type="EC" id="5.6.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the type II topoisomerase GyrB family.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.2" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003918">
        <property type="term" value="F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03366">
        <property type="entry name" value="TOPRIM_TopoIIA_GyrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.670">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002288">
        <property type="entry name" value="DNA_gyrase_B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001241">
        <property type="entry name" value="Topo_IIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013760">
        <property type="entry name" value="Topo_IIA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013759">
        <property type="entry name" value="Topo_IIA_B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013506">
        <property type="entry name" value="Topo_IIA_bsu_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018522">
        <property type="entry name" value="TopoIIA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034160">
        <property type="entry name" value="TOPRIM_GyrB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00204">
        <property type="entry name" value="DNA_gyraseB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00986">
        <property type="entry name" value="DNA_gyraseB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01751">
        <property type="entry name" value="Toprim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00433">
        <property type="entry name" value="TOP2c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56719">
        <property type="entry name" value="SSF56719"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00177">
        <property type="entry name" value="TOPOISOMERASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Toprim" evidence="6">
        <location>
            <begin position="439"/>
            <end position="553"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV58992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="833" mass="93182" checksum="72C86EC16899ADEE" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J151</accession>
    <name>A0A518J151_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Hva1_TUDOR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_50850</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021331">
        <property type="entry name" value="Hva1_TUDOR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11160">
        <property type="entry name" value="Hva1_TUDOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hva1_TUDOR" evidence="2">
        <location>
            <begin position="9"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV59060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="72" mass="7980" checksum="E2A0F230FBA35DE4" modified="2019-10-16" version="1">MSQEFQKNQSVQWNFGSGVGKGKIKDAFRSNVTRTIKGSEVTRNATAEEPAYLIEQDDGDEVLKSQSELTKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J190</accession>
    <name>A0A518J190_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_51390</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="80" mass="8873" checksum="E50E5F66FECCBC1B" modified="2019-10-16" version="1">MSTISVNVPDQIMPAIAKRARNSGFADVNEYVTQYVLRLSERQSEVEELAIEGLQSGPSLPWDKTEVEDMRAALKSKYGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1E0</accession>
    <name>A0A518J1E0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_51840</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="65"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="125"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="154"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV59156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="178" mass="19584" checksum="63F8CA5A5EF9C1F9" modified="2019-10-16" version="1">MGINMARKSRNGRRHNRSKRNGKRQRKRSESPASWKWHILVILLALLGFGAFIMSEFEPIDQLCMAGFSFLCAGLGLLMIGSFTACGEGLPQLIEGSRFEKAFESLARFVIQRARSPLFRLVAKPLSTVFTLALLIVAIPTGVIVAIARPKQTWPSIVYIGGTVLSFLVGILILIIAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1E2</accession>
    <name>A0A518J1E2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">(S)-2-haloacid dehalogenase</fullName>
            <ecNumber evidence="3">3.8.1.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_51800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.</text>
    </comment>
    <dbReference type="EC" id="3.8.1.2" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018784">
        <property type="term" value="F:(S)-2-haloacid dehalogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd02588">
        <property type="entry name" value="HAD_L2-DEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006328">
        <property type="entry name" value="2-HAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00413">
        <property type="entry name" value="HADHALOGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01493">
        <property type="entry name" value="HAD-SF-IA-v2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01428">
        <property type="entry name" value="HAD_type_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021731886" evidence="2">
        <location>
            <begin position="25"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV59152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="273" mass="29707" checksum="62B1F7A6E4F9E603" modified="2019-10-16" version="1" precursor="true">MKRTLFTIALTFCALALTSNTTRAQDAPTDKSSSTANESGAEMPRPKVIIFDVNETLLDLSPLKISVGKALGGREDLLPLWFSTMLHYSLVETLTDNYHHFGEIGTAALMMVAKTQGIELDYDTAKAAIVTPLRSLPPHADVVAGITSLSKSGYKIVSLTNSSAAGVETQFNNAGLTELFEKRYTVETLKKYKPHPDTYRMVLKDLGVRPEEVLMVAAHAWDIAGATNVGLQTAFVARPGKTLYPNAPRPDYVVKDLSELVQVLQKTKPVAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1F6</accession>
    <name>A0A518J1F6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">GLOBIN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_51850</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019825">
        <property type="term" value="F:oxygen binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01040">
        <property type="entry name" value="Mb-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.490.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000971">
        <property type="entry name" value="Globin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009050">
        <property type="entry name" value="Globin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012292">
        <property type="entry name" value="Globin/Proto"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044399">
        <property type="entry name" value="Mb-like_M"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46458">
        <property type="entry name" value="SSF46458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01033">
        <property type="entry name" value="GLOBIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GLOBIN" evidence="2">
        <location>
            <begin position="89"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS01033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV59157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="135" mass="15632" checksum="E4544C0C9B1C1E3D" modified="2019-10-16" version="1">MDDLPPKDLFLQSVARCTASAAFIPAFYDRFTSASDEIRAKFRFTDFEQQNKALKRSLEMCAFAIAGTPEALAELTARAKTHDRDHLNIEPRFYDIWVDTIIETAAEYDDQWSDAIEAAWRRVLSHVVKHMIRKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1T8</accession>
    <name>A0A518J1T8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_53300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="48" mass="5529" checksum="15AEE2D75EF9405C" modified="2019-10-16" version="1">MVELPLEWYYHADRKANHPSQSLHPACPAADKTFIPEKVTHFLKKIVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J299</accession>
    <name>A0A518J299_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">4,5-dihydroxyphthalate dehydrogenase</fullName>
            <ecNumber evidence="3">1.-.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">pht4</name>
        <name evidence="3" type="ORF">Mal33_54990</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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    </dbReference>
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        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="2"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="GFO_IDH_MocA_C" evidence="2">
        <location>
            <begin position="105"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV59464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="306" mass="33920" checksum="71282CEF34091629" modified="2019-10-16" version="1">MAFCDPMKDRRLEVSQRYGINGYPSWEQALENEPLSAAVIASPAPMHIPMARGLAELGLDLLIEKPLSLKTDGISELLETVQQKKLRVGVGFVYRALPALQNMRAAVQSGQFGRIVQVQVTSGQNFPFYRPAYRDIYYADPAQGGGLIQDSLPHQLNAVEWFAGPATKVVVDASHEVLDGVEVEDTLNLIARHGSVMSSISVNQHQYVNEFVITVLCTEGAVRWELKGQRWLAAREIGGDWTEMESFIHERDDYYIRQAEAFLDLLAGKADPLCSLDDGISTLMSTLAILKSRETGGWETVQPVNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J2A2</accession>
    <name>A0A518J2A2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_54940</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013406">
        <property type="entry name" value="CHP02574_addiction_mod"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09720">
        <property type="entry name" value="Unstab_antitox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="72" mass="8125" checksum="1EF77A9FBF4488DD" modified="2019-10-16" version="1">MNLETIIDGFSRDQQSIAMEMLWKRLSQSPDAAAPPSWHQDIVAERVAGLQDGTESLSDWADAKKRLADRLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J2A7</accession>
    <name>A0A518J2A7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sodium/glucose cotransporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">sglT_5</name>
        <name evidence="8" type="ORF">Mal33_55020</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1730.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038377">
        <property type="entry name" value="Na/Glc_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001734">
        <property type="entry name" value="Na/solute_symporter"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00474">
        <property type="entry name" value="SSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50283">
        <property type="entry name" value="NA_SOLUT_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="77"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="117"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="152"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="185"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="228"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="271"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="316"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="376"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="411"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="435"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="477"/>
            <end position="498"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV59467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="503" mass="54039" checksum="B123F11593F61216" modified="2019-10-16" version="1">MAIIDWIILLLYASSTIGLGWYCSRKQEDTSAYFVGSGKMNPVLIGVSLFATLLSTISYLAIPGEVLGKGPIYLTNYLAYPFVYLFVAFVLLPVYMRQRVTSAYELLETQLGLSIRLLGATMFLLLRLVWMALLVYLTAKALAIMIGVGDEMVPWIVLVTGIFAVTYTSLGGLQAVVITDLMQTLLLYGGALLVLGIVTWEMGGLGWFPTEWPDDAWDTQPIFSLDPATRVTVFGSALSVFLWTVCTSAGDQVSVQRFMATKDVKAARRAIAIQLIVAMVVGVTLGLVGIALLGYFQAHPEFMPKDLSLKAQADGLFPHYIASHLPPVVTGLVVSGLFAAAMSSIDSGVNSITAVVMTDFLDRFGLKPTTEKKHLLFARLLAVGIGTTVVLISTFMEYIPGNFMAVTNKTVNLLSVPIALLFFFALFVPFSNAIGVWVGTVASVAVAVTIAFSGVIFGADPDTGLDPISFQWISPAALLTGLIVGTAACVLFAPLYSAKNASR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J2E3</accession>
    <name>A0A518J2E3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Bicarbonate-binding protein CmpA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">cmpA</name>
        <name evidence="1" type="ORF">Mal33_55430</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd13553">
        <property type="entry name" value="PBP2_NrtA_CpmA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044527">
        <property type="entry name" value="NrtA/CpmA_ABC-bd_dom"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="386" mass="43230" checksum="4481B5A6EFFF6A83" modified="2019-10-16" version="1">MSSVGKLALSCLCLLGTVTILHAHFNLGMFDRPQHIAGDENGAVRKSLRVGHLPVTCHLTCPVTSWVSKHSQQHSEFVSWRYTSWPAMTEDIDAGNLDAAFILAPLAMVMQRQGTPVKIVHLGHRDGTAIVVNKDSPYKTFADLRGKRIAIPHRYSNQRILIEKLKDEFGLTNAEITLIDYPPPEMPAGLKSGQFEAYIVGEPFAAKAEMDGFGRVLYFTKDIWPNFISCVLVVTERLIERDPELVTELVQGISASGKWIDQGDDRLMAGLAVEGTPSADGDAIPEQFGRSPRMQAAWIAARQEYYNQDPELLKFVLTRPLDRVSYSRLDLAREDFAEIQDYAQRLGFFSFRPVTADDPFGFDDYCDPSFEQSGMWSLPLESEEPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IME0</accession>
    <name>A0A518IME0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pseudouridine synthase</fullName>
            <ecNumber evidence="3">5.4.99.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rluB</name>
        <name evidence="6" type="ORF">Mal33_01850</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the pseudouridine synthase RsuA family.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.-" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120159">
        <property type="term" value="F:rRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000455">
        <property type="term" value="P:enzyme-directed rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1560">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042092">
        <property type="entry name" value="PsdUridine_s_RsuA/RluB/E/F_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000748">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluB/E/F"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018496">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020094">
        <property type="entry name" value="TruA/RsuA/RluB/E/F_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00093">
        <property type="entry name" value="TIGR00093"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01149">
        <property type="entry name" value="PSI_RSU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S4" evidence="5">
        <location>
            <begin position="24"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="260"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV54235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="389" mass="41692" checksum="39217AB0AE64329A" modified="2019-10-16" version="1">MPNPPRKKKSPQTKVASESETSMVRLQRVLASAGFGSRRKCEELITEGRVDIDGQPVIELGTRVDPRASKIRVDGVSIRPAKLVYFALNKPVGIVTTNRDPQGRPRVIDLINEHQRVFPVGRLDRNSEGLILMTNDGDLSEMLAHPRHGVRKTYQVTVAGLVQAETLKQMREGVHFHEGRFQVEGVSIKRTRGKATELEIVLREGKNREIRRILARLGHKVVQLKRTAIGTLKLGDLPTGAYRPLNSREVKKLRDEVVASQAAAEADQPPRPRKGGARKGVARKTGPATGRPTAGRPAAGKPSAGGKMGAGRGKGVGRSAQAKPAGRRPGSSDIIISSESTGGSAGTVIGAPELAAPPAKPKRPAAGRRGTKKGATRGGAAARGKRKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMF1</accession>
    <name>A0A518IMF1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_02180</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011486">
        <property type="entry name" value="BBP2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07642">
        <property type="entry name" value="BBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021934524" evidence="1">
        <location>
            <begin position="24"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="454" mass="49343" checksum="8DC849B02DF7B11D" modified="2019-10-16" version="1" precursor="true">MKISKLALLAAFACGIHAGSATAQQINTNYFGDVAQVGCFDNEPDCGLDASCCEPACECEAGCDSYGCDSCGGASGGGVFFQDGSLPSLACAGCGTCDLGDPWQLCGNHWGWDKGGWLQLGYTTAGRNGTNFNNHPDRINLHQAWFYMEKVADGSDGLDWGGRVDYVYGVDAQDTQAFGNDGSHWDNGWDNGIYGHALPQAYGEVAYGDLSVKVGHFYTIIGYEVVTAPDNFFYSHAFTMFNSEPFTHTGALATYNLSDNTTIYGGYTSGWDSGFENNGDNFIGGISQQLDDTTNITFAYVAGRFGNISQPGYGGEKGNMFSIVTQKELTNKLTYVNQIDYLKTSIEGAAGKLNQRDTFDINNYLIYQINDCWAVGGRFEWWNVEGNGYNLAPGDNNDIYDLTLGVNYRGNANWVIRPEVRWTWDKDANINGLAVNENAAASQTTFGIDGIYTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMJ1</accession>
    <name>A0A518IMJ1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_02590</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022190876" evidence="2">
        <location>
            <begin position="21"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="155" mass="16212" checksum="45B9E03BB0EF641B" modified="2019-10-16" version="1" precursor="true">MNLQKLASKSAAIAATFALAMMTGCGSGGLPDDAAAVEGVVTYQGSPVADAVVTFRSQDGFSAVGKTAPDGRYQLSSASIPGGTKIGDYQVTVVKREKLDNAMLTEEDPNYSSQQQVAPQKPKHLVPERYSRPTTSGLEATVATGPNEINFDLTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMJ9</accession>
    <name>A0A518IMJ9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">30S ribosomal protein S21</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 7" type="primary">rpsU</name>
        <name evidence="7" type="ORF">Mal33_02710</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the bacterial ribosomal protein bS21 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00358">
        <property type="entry name" value="Ribosomal_S21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001911">
        <property type="entry name" value="Ribosomal_S21"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038380">
        <property type="entry name" value="S21_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21109">
        <property type="entry name" value="PTHR21109"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01165">
        <property type="entry name" value="Ribosomal_S21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00976">
        <property type="entry name" value="RIBOSOMALS21"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00030">
        <property type="entry name" value="S21p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV54320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="64" mass="8030" checksum="802B340D91B018F0" modified="2019-10-16" version="1">MVKLVVRDRETIQEAVRRFRKLVERSGIKKEMRRREFYEKPSEINRRNRLRAERRSRRNRMISG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IML8</accession>
    <name>A0A518IML8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Methyltransf_11 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_02800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="1">
        <location>
            <begin position="185"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="355" mass="38682" checksum="205E7FE00300D8F5" modified="2019-10-16" version="1">MIETLDAPLQDTLSREAEVASSASLPSESDRAGAGETAAASLRIGREAIEILQCPGCGGALSVAADAMQCDACERTYPVADGVPVLVVPEKSLFDIETFTNAEPTFFRPVGKVRELISGCLPDVTLNVSSDKVYARMLQQMLEKSEHPVVLVIGGGVIGGGMDCLVDDPRITLIETDAAIAPRTSLVCDGHDLPFADQSVDAVIVQAVLEHVVDPHRCVQEIHRVLKPGGLVYSDTPFMQQVHGRQFDFTRFTRLGHRRLFRMFDEIESGISCGPGTALAWSLRYFLLSFFASDRMRAAVSLASRLMFFPLKYCDRYLVNKASASDAASAFYFYGSRIETPLSDRELVASYHGGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INP9</accession>
    <name>A0A518INP9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Carbon starvation protein A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">cstA</name>
        <name evidence="11" type="ORF">Mal33_06760</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009267">
        <property type="term" value="P:cellular response to starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025299">
        <property type="entry name" value="CstA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003706">
        <property type="entry name" value="CstA_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02554">
        <property type="entry name" value="CstA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13722">
        <property type="entry name" value="CstA_5TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="85"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="130"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="161"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="186"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="224"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="256"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="302"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="350"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="415"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="481"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="512"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="544"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="581"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="domain" description="CstA" evidence="9">
        <location>
            <begin position="2"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="domain" description="CstA_5TM" evidence="10">
        <location>
            <begin position="421"/>
            <end position="561"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QDV54719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="621" mass="65888" checksum="5BE1CBA8CB5CABAD" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INR3</accession>
    <name>A0A518INR3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Double zinc ribbon</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Mal33_06910</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025874">
        <property type="entry name" value="DZR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001876">
        <property type="entry name" value="Znf_RanBP2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12773">
        <property type="entry name" value="DZR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00547">
        <property type="entry name" value="ZnF_RBZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="21"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="51"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="RanBP2-type" evidence="5">
        <location>
            <begin position="123"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="RanBP2-type" evidence="5">
        <location>
            <begin position="151"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV54731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="177" mass="18703" checksum="5BAA33A4A7EB0DA8" modified="2019-10-16" version="1">MSDEERINPGHLKTRQLLRKIGPLIFGVGALFTIVGMASFFMSFGSFGPPRFFWCCFVGMPLMFVGSAMSGYGFMGAITRYQAGEIAPVGKDTFNYMAEETRGGVQAVASAIGAGLNQSARQSSVACPSCGTANDQDAKFCDSCGTAMLSTCGSCGAVNDSDAKFCDRCGTQLSQNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INV8</accession>
    <name>A0A518INV8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CAAX amino terminal protease self-immunity</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_07200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071586">
        <property type="term" value="P:CAAX-box protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003675">
        <property type="entry name" value="Rce1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02517">
        <property type="entry name" value="Rce1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="164"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="189"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="246" mass="26606" checksum="B8C449FB67210E07" modified="2019-10-16" version="1">MMVLVVTVVRIIRPFRNKPCSKMDDPDLDDNFEPPVLESSDRFFMAAVGFEVGLGVVAVVVGSFLGPSANELVPPLSDVWAILWGVGLGALLALPMVAMVQGLQKLRIPQVEEINRLGRDRMLPLMENLSNWELAILSICAGVGEELLFRGWLQTWITGSESEWSVTSMAIGIFVASLVFGLAHAITKLYVIVVFAMGILFGIMLVATGNLLVPIAAHAVFDFIQLKLAVSELKKEAAGGEVSAPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INX0</accession>
    <name>A0A518INX0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Amidohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_07500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032465">
        <property type="entry name" value="ACMSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21240">
        <property type="entry name" value="PTHR21240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04909">
        <property type="entry name" value="Amidohydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="2">
        <location>
            <begin position="81"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="410" mass="47189" checksum="EB8F617253A3E47D" modified="2019-10-16" version="1">MSLARILSFCCAIGLTTVWWVALVDAQQPATTPVETASPQEQLLMPLDGRDGRELLLRNFRPKSRLRVPENPRDAAKFPVVDVHTHLSYRLKDDPEALDAFVELMDRNNIAVCCSLDGRLGDKLQQHMRYLWTKYRDRFVIYANVDWQGSGDANDPATWACNQPGFVRQTVMQLEAAAEQGVSGLKIFKGFGLGYRGEDRNLLAIDDLRWDPIWEACGRLGLPIIMHVADPAAFFDSIDPQNERWEELSRHPDWSFHGDDFPSREALLEARNRVIERHPKTKFIGAHVANNSEDLETVAAWLDRYPNLSVEFASRIGELGRQPYSARDFIIKYADRVMFGTDGPWPETRIRLYWRFLETRDQYFPYSEKEFPPQGLWQIYGLYLPDDVLRKVYSENAARLIPGVRQRLGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP80</accession>
    <name>A0A518IP80_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5 6">50S ribosomal protein L19</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">rplS</name>
        <name evidence="7" type="ORF">Mal33_08370</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6">This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the bacterial ribosomal protein bL19 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00402">
        <property type="entry name" value="Ribosomal_L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038657">
        <property type="entry name" value="L19_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001857">
        <property type="entry name" value="Ribosomal_L19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018257">
        <property type="entry name" value="Ribosomal_L19_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15680">
        <property type="entry name" value="PTHR15680"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01245">
        <property type="entry name" value="Ribosomal_L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002191">
        <property type="entry name" value="Ribosomal_L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00061">
        <property type="entry name" value="RIBOSOMALL19"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01024">
        <property type="entry name" value="rplS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01015">
        <property type="entry name" value="RIBOSOMAL_L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 7" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV54872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="117" mass="13429" checksum="277C9BA818DECE4B" modified="2019-10-16" version="1">MSQQVMDLVEKTCLKSDVPQFDIGDTVDVHTKILEGAKERIQVFTGVVIARSGSGTREMFTVRRMVAGEGVERKFPLHSPRVERVEVKRSSVVRRAKLYFLRDRVGKAVRLKERRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP95</accession>
    <name>A0A518IP95_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_08750</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011453">
        <property type="entry name" value="DUF1559"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07596">
        <property type="entry name" value="SBP_bac_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="311" mass="33649" checksum="DBD4718893C3C96B" modified="2019-10-16" version="1">MNISKHRMGFTLVELLVVIAIIGILVGLLLPAVQAAREAARRMQCTNNQKQLGIALHNYHDTHRTFPFGNGGTKSLSGGPGYSAVSLMLPFMEQTPLYDSINFSLPLTDPFNDTARLAEVAGFLCPSDRENPQPQTGGAINYMGNKGSLHLWNDPSQTGIFLSDKSFRFRDITDGTSNTSAFSERLLTDGNNGVSDLRSDVFLGTGDPATPDEAIQMCYATDATNLANQFPLFMGAPWINGQHTYTHVDVPNRRSCGFFPTKATMPASSRHPGGANSGLCDGSVRFISENIDRTLWRAIGTRSGGEITSGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPB7</accession>
    <name>A0A518IPB7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_08990</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="175"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="205"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="233"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="263"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="296"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="459" mass="50780" checksum="D43888B479F97D25" modified="2019-10-16" version="1">MKNRVDRRRQTRPSRSLPWWRVGPCLLAIAALAWLPSFGTPISTATPAGQSPPIEATLVAHWQQPAAPPISLPEIDLSDLEADELGDGEPLSAAGIEKNLKGSMTKEQISAADLAAANQMVEQLTPVDWLGPLAPVALSPFFGITCLSGLALWSPEWMPGNGLLDAATPLKNPNLFWAFAALTIITSLPRLSKVSKPIAVAVDKVEAYAGIITLIAIRYIASPNEVLDESPEIVEAGIVSGTVGALLSVAMVINVLVINSVKFFFEFLIWLTPIPFLDACFEFANKTMCAGLMALYALSPTLATLLNLAVFIVCLLVLRWINRRVHFYRHMVFDSLWPMFQKTYGRPSRAELVVFPKTDWNGFQDKACITLCRHDRGWTMRQRRWFRTPLSSDLPADAKLKITRGWLTNTLEIRTTEPVVMIFSRRYHGDLHTVAELIGAEVEVVEETPQPKPAKTEFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPC3</accession>
    <name>A0A518IPC3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Y1_Tnp domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_09210</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002686">
        <property type="entry name" value="Transposase_17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036515">
        <property type="entry name" value="Transposase_17_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM01321">
        <property type="entry name" value="Y1_Tnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143422">
        <property type="entry name" value="SSF143422"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Y1_Tnp" evidence="1">
        <location>
            <begin position="43"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="209" mass="24540" checksum="EB299073483E3E89" modified="2019-10-16" version="1">MPTNPETMYRWRKMSPEQRREVLAERRRYGRPPHSPPHIESDTTSCYLITAACFEHRPFIGYASQRMSAFEQELVDLLGTQCSHVYAWTILPNHYHSLVDTPSVKGLLKKLGQLHGRNSYLWNRVEDCRGRQVWCNAAETAMKSEGHFYATWNYVLNNAVRHGYVTQWIEWPYCNAVEYLQAIGRDLALKRWQAYPPYDFGKGWDPPEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPE8</accession>
    <name>A0A518IPE8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Holliday junction ATP-dependent DNA helicase RuvA</fullName>
            <ecNumber evidence="7">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">ruvA</name>
        <name evidence="9" type="ORF">Mal33_09130</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="7">Forms a complex with RuvB.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the RuvA family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="7"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009378">
        <property type="term" value="F:four-way junction helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00031">
        <property type="entry name" value="DNA_helic_RuvA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003583">
        <property type="entry name" value="Hlx-hairpin-Hlx_DNA-bd_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000085">
        <property type="entry name" value="RuvA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="SMART" id="SM00278">
        <property type="entry name" value="HhH1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="SSF47781"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6 7" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 7 9" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 7 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0742">SOS response</keyword>
    <feature type="domain" description="HhH1" evidence="8">
        <location>
            <begin position="107"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="HhH1" evidence="8">
        <location>
            <begin position="141"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV54947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="235" mass="25971" checksum="8CFA97A90F005D63" modified="2019-10-16" version="1">MSLCYVPWLRWGRCGQRVSNYAEFCTLITKITGKLASLNDESAVLDIPPFEYEVFIPDFTRRQLQGKIGSDIALHTLNYIDGNAAQGGRLSPRLVGFIAPVEKQFFELFCSVDGVGVKKALRAMVRPVKEMAVMIEQQDAKSLSSLPGIGPATAERVIAKLRRKMPRFALLVGRDATPEDGDDQSDVVRDTFDALLALGHGEADARQLIDDAMASKKKFKDTESLLTAIYQKSSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPG8</accession>
    <name>A0A518IPG8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_09590</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="420"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="614"/>
            <end position="674"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1017" mass="111682" checksum="F408238B174AEC5A" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPY8</accession>
    <name>A0A518IPY8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Bifunctional phosphatase/peptidyl-prolyl cis-trans isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_11120</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000413">
        <property type="term" value="P:protein peptidyl-prolyl isomerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044666">
        <property type="entry name" value="Cyclophilin_A-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625">
        <property type="entry name" value="PTHR45625"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="SSF50891"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="2">
        <location>
            <begin position="305"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="475" mass="52219" checksum="90F70C329FA80E19" modified="2019-10-16" version="1">MGAWDRAADWILKMRVEMSLRILAAPLLLAICLTNLAAAQESDGDQTAAAETPAAAEQPPAEDAKPAAEENPAEEKPAAEKPAEEKPAAEEKPAAEEKPAAEKPAAEDEKTVASPEEVKKLQAVFDQRVKEWRKATQEFWAEVNEFHTAGGDVKFSEQIRWAERESATRDAMQAAFLAASDLVFVDHENRDARTFMAQSILYHAQNDWYEGLKDAALAMLEVGIKDVQLNVIAGVAAAATGDFEVAKENLKLTPAEGDEGLLKVARRMNFMLDPLQEAWEKEQKIRQAEAEADDLPRVLLKTTRGDVLVELFENEAPNTVASFISLVEDGFYSNVPFYQVVEHEFAQTGDRDGDGSGTADYRVRDEATGERGIFRGSLVLAKIPNPNAAHNPDVPGTIPDTGSSQFLITLLPFNPDYKELCCFGRVISGMGAISTLNRAKVEKEKDAPVVLPDSIIEAEVVRKRDHEYKPETLPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPZ0</accession>
    <name>A0A518IPZ0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Amino_oxidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_11160</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amino_oxidase" evidence="1">
        <location>
            <begin position="22"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="477" mass="53759" checksum="4D821ED2A215EEBB" modified="2019-10-16" version="1">MPKDFLAKAADEYDVIVIGSGLAGLTTANILGRHGHRVLLLEQHYKLGGLATWFRRPGGHIFDISLHGFPAGMIKSCKRYWNDDISDRIVQLKNVRFENPMFSLTTTFNRKDFTKLLTEQFAVEQSAVEGFFDTARSMNFYDDQTTTTRQLFDRFFPGREDVIRLLMEPITYANGSTLEDPALTYGIVFSNFMSKGVFIYEGGTEDLIARMQKELKKNNVDICINCPVDKINVKNGQVESVEVHNRTIRTKSVISNSNLRSTIFNMVGSEHFDPSFVEEAEAVRLNNSSTQVYMAMKPGVEIDESCGDLLFTSTAPLFRTEALLSRDITSRTFSFYYPRTRPEGKRRYAVVSSTNARWEDWSGLSETQYEASKQELIETTVAALDKFVPNVREKIDWVEAATPRTFNHYTRHQLGASFGTKFEGLAVSRKLPEQIGGLYHAGSVGIIMSGWLGAINYGVIVANDVDQRLMKQEAAPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQ29</accession>
    <name>A0A518IQ29_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">General stress protein 18</fullName>
            <ecNumber evidence="3">3.2.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">yfkM</name>
        <name evidence="3" type="ORF">Mal33_11640</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C56 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.-.-" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016798">
        <property type="term" value="F:hydrolase activity, acting on glycosyl bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008152">
        <property type="term" value="P:metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006286">
        <property type="entry name" value="C56_PfpI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42733">
        <property type="entry name" value="PTHR42733"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01382">
        <property type="entry name" value="PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51276">
        <property type="entry name" value="PEPTIDASE_C56_PFPI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DJ-1_PfpI" evidence="2">
        <location>
            <begin position="4"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="195" mass="20604" checksum="851235A09DFD8501" modified="2019-10-16" version="1">MAAKKILMLVGDFVEDYEAMVPLQILLCVGHQVDTVCPGKQAGQTVATAIHDFEGHQTYSEKPGHNFAINADFDSADAAAYDALVIPGGRAPEYLRMNSKVIDLVKAFHAADKPIAAVCHGPQILVAAGLLEGRKCSAYPAVAAEVTVAGGQFVPASDGFDNAHVDGNLVTAPAWPAHPAWMRAFLELLGSEIKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQ37</accession>
    <name>A0A518IQ37_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_11530</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021727">
        <property type="entry name" value="DUF3299"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11736">
        <property type="entry name" value="DUF3299"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="199" mass="21952" checksum="4E0373FE6D3EBF8E" modified="2019-10-16" version="1">MLSHSPASSMLRIATCWIFASTVVLPLTAAPIEKEKGQEEQAAAATTERPARGVRPTPTDAKPAAPPRRMPPKRKGEISFDTILFEMDKEADYDPSMVTPEIKALQGKEVTIRGFILPASVFQQVGIKQFVLVRDNQECCFGPGAALYDCIMVKMTGDNSANFSTRPVAVKGKFQLTDKYKYPDGKYLAIYEMEATKVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQ73</accession>
    <name>A0A518IQ73_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Formyltransferase/hydrolase complex Fhc subunit A</fullName>
            <ecNumber evidence="2">3.5.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">fhcA</name>
        <name evidence="2" type="ORF">Mal33_12190</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.5.1.-" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013108">
        <property type="entry name" value="Amidohydro_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012027">
        <property type="entry name" value="Formylmethanofuran_DH_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07969">
        <property type="entry name" value="Amidohydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006453">
        <property type="entry name" value="FwdA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03121">
        <property type="entry name" value="one_C_dehyd_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Amidohydro_3" evidence="1">
        <location>
            <begin position="38"/>
            <end position="482"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="544" mass="60052" checksum="FF70C8567726BD96" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQI9</accession>
    <name>A0A518IQI9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_13320</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="305" mass="34014" checksum="CCBF9C4411838C2D" modified="2019-10-16" version="1">MDPTATYPLCLLFGIHYPSFISEEEPAIGHLRTRFSGDTTGLVEPVQLLAVLSTNSAQFLWCELSREVVGGWGQIVLTGSEDNHEVWYDSRVDNVLDAFRTVSERQPPDFVPMPAPDSCLVSISLDDLPSDPFPGYKIEYEDVSPTRQGKWAYEMKKHLRAGRIGTQTSRERVILRKDLRRIDPSMFKGQVGSTIPETGFSSKPGRTSLQVAGQFESGVCLDIDIYWIDFIREELAEDLSSKIIASFRDTPFDADLESASKWTLDLPYFNVPIAESLAAASTRCTPSRTAAQSPRLLRTSVSAIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQJ7</accession>
    <name>A0A518IQJ7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">zf-HC2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_13380</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041916">
        <property type="entry name" value="Anti_sigma_zinc_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027383">
        <property type="entry name" value="Znf_put"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13490">
        <property type="entry name" value="zf-HC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="zf-HC2" evidence="1">
        <location>
            <begin position="6"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="308" mass="33027" checksum="7E5D193A2E10B911" modified="2019-10-16" version="1">MSTNDCKTVQPYLSAYYDGELAAGQATTVAEHVESCELCAVELSSFESIGSDFAQTPIPANPSDLWERIERELPTAAEPETLSRRFATFATWVRASPYGGGLVSMAASALVMLGAALWFGGDNNPDMAGGGSMAMHGSHGHQHDGKEAMSAEHMAEFAGVMDDYLQKLPSDPDGAEQMLLTKYDGETVDSDGAVKLVGYRPIVSSGLPEGYSLASTSVLKMPCCTCVKAVCKRSDGSTLVLFEHDDEETAWFGDRRQSMAMCGDKDCCLVDLDSSIAATWKQGSRSVTAVGVRDQDEVTKLVTWLDKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQW4</accession>
    <name>A0A518IQW4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Site-specific tyrosine recombinase XerC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_14620</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyr recombinase" evidence="3">
        <location>
            <begin position="184"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV55487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="376" mass="41923" checksum="66AB94ABD1059F2D" modified="2019-10-16" version="1">MAKSTAARRQRKDLKLSVHKASGYWCKVIAGHRYYFEKVADDPDGVESTDQLIEVRKGNPKPPRSGAFLIKDACEAWIQHKKQKLDAGEIVQDTWNEYHHTCEMTIAALGKETEVESLSPADFGKLRTSLAKRYGPTALGKHIGQVRSLFKHAYTEGLIDRPAKFGANFVKPKAKVLRKTRLEKGRQDFTAAEILAMLKVADPKWKSMILLGVQSGFGNRDVAELTPEVVDLKTGWIEYARSKTAIHRRVPLWPETIAAIAETIKSHPGGSPYLFVGDRGRDFTTENRTGGNRVSGAFKSVLNAAKLPTTGRTFYALRRTFQTQAEESGDLVAVRALMGHADGENDMSARYRQRVSDARLRRVVDTVHGWLYGGAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IR04</accession>
    <name>A0A518IR04_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative major pilin subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_14980</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011453">
        <property type="entry name" value="DUF1559"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07596">
        <property type="entry name" value="SBP_bac_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="298" mass="32857" checksum="9A74BA2CAB3E36CC" modified="2019-10-16" version="1">MNHASHLYRGGRRRRGFTLVELLVVIAIIGILVGLLLPAVQAAREAARRCQCMNNITQLGLAMHHHEFSTEHLPAGVINPDGPIRSAESGDHISWVVQILPFIEQNALYNHFDQAAGAYAAVNREARQQTIPTMHCPSYPGNYRRGRHSEPEIVSGNYSGCHHDVEAPIDADNNGLLFLNSDIRYSQIPDGSTQTILLGESLPFANDLGWASGTRATLRNTGTLLAAYNRLNQLPDQAEPDPSEEPLYVGGFGSTHPGGALFSFADGSTRFLSQNIDPELFRRYGNRQDGELTGWEYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IR86</accession>
    <name>A0A518IR86_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Thiol-disulfide oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_15400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012336">
        <property type="entry name" value="Thioredoxin-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13905">
        <property type="entry name" value="Thioredoxin_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="2">
        <location>
            <begin position="371"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="533" mass="56636" checksum="80521CD891DE37C5" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRG6</accession>
    <name>A0A518IRG6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="11">ABC transporter ATP-binding/permease protein</fullName>
            <ecNumber evidence="11">3.6.3.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Mal33_16670</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="3.6.3.-" evidence="11"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="FHA"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC_2_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="FHA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SSF49879"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 7 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="617"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="649"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="679"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="742"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="domain" description="FHA" evidence="9">
        <location>
            <begin position="22"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="FHA" evidence="9">
        <location>
            <begin position="135"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="215"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="260"/>
            <end position="267"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QDV55688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="769" mass="83566" checksum="D4816F43098EE7CB" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRI7</accession>
    <name>A0A518IRI7_9BACT</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_16700</name>
    </gene>
    <organism evidence="2 3">
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        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
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    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032287">
        <property type="entry name" value="DUF4838"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029018">
        <property type="entry name" value="Hex-like_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16126">
        <property type="entry name" value="DUF4838"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="672" mass="75750" checksum="514F8AEDFCCC07D5" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRN3</accession>
    <name>A0A518IRN3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cell division protein FtsQ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ftsQ</name>
        <name evidence="2" type="ORF">Mal33_17270</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0131">Cell cycle</keyword>
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    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="300" mass="32732" checksum="EED5EBDAA5CB4BDD" modified="2019-10-16" version="1">MGGKKHKQVKSTASDSGRSSLGGAIGGMIKAPAALAFLWPVLLVTGGYLAWHRWGADQINRNYNSLQIEKVQISPLPSYIRSNVIESVFRATDLTKISLLDPQATAQIANAFATSPWIDSVRRVQKTSTGNVDVHVAYRRPVAMVKVVSRHPEVDGMSFFPVDGHSVLLPTDDFSRADTLNYIHIIVQRDTYPISGVGSKFGDTKVADAALLALLLCPHRETLGIEAITITQRPPHDERPQLLNLVLKSGKQIVWGSAPGKELNNEPHASVKLQALLNDSNRSLHDLHVAQPLAADPARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRT3</accession>
    <name>A0A518IRT3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase DDE domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_17710</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025161">
        <property type="entry name" value="Put_IS4/IS5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002559">
        <property type="entry name" value="Transposase_11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01609">
        <property type="entry name" value="DDE_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13340">
        <property type="entry name" value="DUF4096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_1" evidence="1">
        <location>
            <begin position="95"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="272" mass="31350" checksum="7FF61F096CF5EDC6" modified="2019-10-16" version="1">MPRHRLTDREFNAIRHLLPKQCPGKPGRRWSNHRTVIDGILWITKTGSPWRDLPEQLGKWQTVYARFRRWTKEGLWARIYQTLLKRLDALEKIDRSLWCVDGSVIRAHRSASGMIPQSEKNDELVALGRSRGGYSTKIHVLCDGEGTLLGITATGGQRHESTELENLIASCELSLHRYDSRPEVIAGDKGYSSNAIRQFIRDRQIKPVIGSKANESRDANFDREAYRRRSIIERLIGWLKESRRVATRYDKLACSYLAFVQLAATRRVLKLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IS23</accession>
    <name>A0A518IS23_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pup deamidase/depupylase</fullName>
            <ecNumber evidence="2">3.4.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">dop_2</name>
        <name evidence="2" type="ORF">Mal33_18740</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.4.-.-" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019941">
        <property type="term" value="P:modification-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010498">
        <property type="term" value="P:proteasomal protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004347">
        <property type="entry name" value="Pup_ligase/deamidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42307">
        <property type="entry name" value="PTHR42307"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03136">
        <property type="entry name" value="Pup_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="156"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="233"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="560" mass="63020" checksum="F6767A711FF6DA69" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IS52</accession>
    <name>A0A518IS52_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Methionine--tRNA ligase</fullName>
            <ecNumber evidence="16">6.1.1.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">Methionyl-tRNA synthetase</fullName>
            <shortName evidence="16">MetRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16 21" type="primary">metG</name>
        <name evidence="21" type="ORF">Mal33_18620</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 16">Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 16">
            <text>ATP + L-methionine + tRNA(Met) = AMP + diphosphate + L-methionyl-tRNA(Met)</text>
            <dbReference type="Rhea" id="RHEA:13481"/>
            <dbReference type="Rhea" id="RHEA-COMP:9667"/>
            <dbReference type="Rhea" id="RHEA-COMP:9698"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78530"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="16">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="16">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 16">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 16">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 16">Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.10" evidence="16"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004825">
        <property type="term" value="F:methionine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006431">
        <property type="term" value="P:methionyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07957">
        <property type="entry name" value="Anticodon_Ia_Met"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00814">
        <property type="entry name" value="MetRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02800">
        <property type="entry name" value="tRNA_bind_EcMetRS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00098">
        <property type="entry name" value="Met_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041872">
        <property type="entry name" value="Anticodon_Met"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004495">
        <property type="entry name" value="Met-tRNA-synth_bsu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023458">
        <property type="entry name" value="Met-tRNA_ligase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014758">
        <property type="entry name" value="Met-tRNA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015413">
        <property type="entry name" value="Methionyl/Leucyl_tRNA_Synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033911">
        <property type="entry name" value="MetRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029038">
        <property type="entry name" value="MetRS_Zn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002547">
        <property type="entry name" value="tRNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45765">
        <property type="entry name" value="PTHR45765"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09334">
        <property type="entry name" value="tRNA-synt_1g"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01588">
        <property type="entry name" value="tRNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01041">
        <property type="entry name" value="TRNASYNTHMET"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57770">
        <property type="entry name" value="SSF57770"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00398">
        <property type="entry name" value="metG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00399">
        <property type="entry name" value="metG_C_term"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50886">
        <property type="entry name" value="TRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15 16 18" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="12 16 18" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 16" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 16 18" id="KW-0436">Ligase</keyword>
    <keyword evidence="9 16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 16 18" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14 16 18" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13 16 17" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="7 16 17" id="KW-0820">tRNA-binding</keyword>
    <keyword evidence="11 16" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="TRNA-binding" evidence="20">
        <location>
            <begin position="579"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="541"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="16">
        <location>
            <begin position="12"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="16">
        <location>
            <begin position="329"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="146"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="156"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="332"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="RuleBase" id="RU363039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="QDV55883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="681" mass="76130" checksum="D66C9670DF322754" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IS59</accession>
    <name>A0A518IS59_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SGNH_hydro domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_18930</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021709431" description="SGNH_hydro domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="domain" description="SGNH_hydro" evidence="2">
        <location>
            <begin position="126"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="379" mass="41922" checksum="AB74A0A44A3B5B68" modified="2019-10-16" version="1" precursor="true">MIRSVCTLLLFCLVVPAWGQQTETDLQLTLPPEIYVVPGVPTNIYFDNIVLTQSPDKYRFDVVCDFGQSEQHHWTWTPTAGDVGVYPIRVDLYSADDTLLDSAASVLRVTAGAASPSSEPIQILIIGDSLTHASAYPNEIARLMTEDAKQPWKMLGTHKPASAAADVAHEGYGGWTWWNFVNKYEPNPDGTHRKRSSPFVYLNDESKPVLDMPRYFKEQCDGQLPDYVVIKLGINDLFSAPAGDVAGTDAKIDTVFGYADQLVAAIRAAAPNATIGICLTTPPNARQEAFEANYKGRYSRWGWKQIQHQLVQRQMQYIADKSDPQILIVPTQLNLDPVDGYPDNNSVHPNKSGYQQIGSSIYAWLQHQLAGKSPAPAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISF5</accession>
    <name>A0A518ISF5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">VWFA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_19980</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VWFA" evidence="2">
        <location>
            <begin position="213"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="673"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="674"/>
            <end position="688"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="710" mass="79173" checksum="0AF37CC708926B9C" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISG6</accession>
    <name>A0A518ISG6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Quercetin 2,3-dioxygenase</fullName>
            <ecNumber evidence="5">1.13.11.24</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">yhhW_1</name>
        <name evidence="5" type="ORF">Mal33_19820</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the pirin family.</text>
    </comment>
    <dbReference type="EC" id="1.13.11.24" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008127">
        <property type="term" value="F:quercetin 2,3-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012093">
        <property type="entry name" value="Pirin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003829">
        <property type="entry name" value="Pirin_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041602">
        <property type="entry name" value="Quercetinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43212">
        <property type="entry name" value="PTHR43212"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02678">
        <property type="entry name" value="Pirin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17954">
        <property type="entry name" value="Pirin_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006232">
        <property type="entry name" value="Pirin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pirin" evidence="3">
        <location>
            <begin position="7"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="Pirin_C_2" evidence="4">
        <location>
            <begin position="146"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV56003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="232" mass="25666" checksum="E9EBE1589AA88E0B" modified="2019-10-16" version="1">MIKVRKADDRGHADHGWLDAHHTFSFASYRDPTQMGFRALRVMNEDRIAAGQGFGTHPHRDMEIVTYVLEGALEHKDSLGNGEVLRPGEFQRITAGTGITHSEFNPSADEPTHLYQIWLHPNRSGIEPSYEQKRFDDDKLSNALRLVASPDSSDGSLLIHQDARIYLSKLDAKHSVQTPLAAGRHGWLQVLRGSITLNGEALDTSDGAAISDEPTLELTATTDAEIMLFDLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISJ9</accession>
    <name>A0A518ISJ9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_20380</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="85" mass="9462" checksum="8403C890354307FC" modified="2019-10-16" version="1">MTEYRFRVVINHRVVNEHQMLELADRLAAAGCDDGHLGGHSDGIEVVFDREAASRDEAMRSAIEQIEGCGLVVKRIELDREVLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISK4</accession>
    <name>A0A518ISK4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_20560</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="32" mass="3650" checksum="8FBF98747132C14A" modified="2019-10-16" version="1">MDSDIRRSQRPLADGTIVQIDGDSLNHHPLEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISP5</accession>
    <name>A0A518ISP5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 4">Orotate phosphoribosyltransferase</fullName>
            <shortName evidence="4">OPRT</shortName>
            <shortName evidence="4">OPRTase</shortName>
            <ecNumber evidence="2 4">2.4.2.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 5" type="primary">pyrE</name>
        <name evidence="5" type="ORF">Mal33_20520</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>diphosphate + orotidine 5'-phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + orotate</text>
            <dbReference type="Rhea" id="RHEA:10380"/>
            <dbReference type="ChEBI" id="CHEBI:30839"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57538"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="EC" id="2.4.2.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1 4">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.10" evidence="2 4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00119"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004588">
        <property type="term" value="F:orotate phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01208">
        <property type="entry name" value="PyrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023031">
        <property type="entry name" value="OPRT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004467">
        <property type="entry name" value="Or_phspho_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00336">
        <property type="entry name" value="pyrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 4" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="5-phosphoribose 1-diphosphate binding" evidence="4">
        <location>
            <begin position="126"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>orotate</name>
            <dbReference type="ChEBI" id="CHEBI:30839"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>orotate</name>
            <dbReference type="ChEBI" id="CHEBI:30839"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV56073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="187" mass="19572" checksum="62F33B0DA0537995" modified="2019-10-16" version="1">MSAEYDREALKALLREFALQTGTFTLASGKTASYYLDCRQITLHPQGANQIAAGMLAMLGDRVNQISAVGGMAIGADPITASIVTLAGQQGLPLRGFMVRKEPKGHGAGRQVEGPVAEGQSVYIVEDVITSGGSALQAVDAAEAFGLKVLGVLGIIDRLAGGEAKFAERGLKLETLLTIRDFGIEPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISZ0</accession>
    <name>A0A518ISZ0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_21930</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011486">
        <property type="entry name" value="BBP2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07642">
        <property type="entry name" value="BBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022147283" evidence="1">
        <location>
            <begin position="28"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="414" mass="45109" checksum="4B973BFA894BD4B9" modified="2019-10-16" version="1" precursor="true">MLRSTVGLWSLSIAVMFIAAARQPAAAAECTPVTAECDALQCDADTVAQTGSLASLLNDCRETSGVAMGGWISAGLTLNGDGNRSGTGNAPYGYNNVSDGVVVNQIWMFAERQIAEDGLDWGFRIDALFGTDGPDNQAFADQTWDFGWDSGRDYGAAIPQLYADVRIDDLAIRAGYFLTPIGWESVRAPLNFFYSHSYTFYYSEPNTHSGFLATYDVNDRLTLSGGWTMGMDSSFANDLHASTFLGGATLAISEQTTLTWSLLAGDWGDGTGRDGVPSDEGDIYIHSLILEHQVSDRCSYVLHNDLGANTNQATAPDAHWYAIVQYLMVEINDAWQAGTRVEWFRDDGGVRVGDSAADAGDYFEVTLGLNWHHESQWIVRPEVRWDAAGGGLQPFDDGSEDDFFTYAVNAVRTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IT45</accession>
    <name>A0A518IT45_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">EcoKI restriction-modification system protein HsdS</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_22390</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the type-I restriction system S methylase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="REBASE" id="355347">
        <property type="entry name" value="S.PbaMal33ORF22380P"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.220.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000055">
        <property type="entry name" value="Restrct_endonuc_typeI_TRD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044946">
        <property type="entry name" value="Restrct_endonuc_typeI_TRD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01420">
        <property type="entry name" value="Methylase_S"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0680">Restriction system</keyword>
    <feature type="domain" description="Methylase_S" evidence="4">
        <location>
            <begin position="89"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="Methylase_S" evidence="4">
        <location>
            <begin position="238"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV56257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="446" mass="49911" checksum="E84C0A4AC554FEE7" modified="2019-10-16" version="1">MNDRVSGYDVEIPAEWTLERVRDLTSRVGSGITPRGGSDVYQTEGVLFIRSQNVRFEGLNLSDVAYIDRKTHRSMDGSKAMPFDVLLNITGASIGRCCVLPSGLGDVNVNQHVCTVRLEQVTQQDAEFLSSALASPIGQNQIFRLNAGGNREGLNYEQLRAIEVPWPRPNERRKIARILTTVDNLIEKTEALIAKYQAIKQGMMHDLFTRGVDSSGQLRPTQQQAPDLYKQSELGWIPKEWDEDTLGNICTWMSGGTPSKSNESFWRGTIPWVSPKDMKVFEISDSEDHISEEAARVGTRRVPAGTVLIVIRGMILAHSFPVAITTRDVTFNQDMKSLCFDDAETGRFVAHWFVAHRAKMVALATASSHGTKRFDLADVYSIPIGMPTKTERKRIVERIDSLDSNRKAEEQYLSKLRTQKSGLMQDLLTGRVRVKVDETEEVAAHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IT50</accession>
    <name>A0A518IT50_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lipase (Class 3)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_22480</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002921">
        <property type="entry name" value="Fungal_lipase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01764">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lipase_3" evidence="1">
        <location>
            <begin position="115"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="340" mass="37900" checksum="AE52CBE134256623" modified="2019-10-16" version="1">MLFGGIGGFLAVLLVIIVGLFASPSNDSVDIEDRTDWEPPTEEELTPKELLALGWSSHDPIAHWPVASLMLELSDIAYLPPATAREKIRELGWESESINAGSMQGYVIDAGDDSIVTFRGTEGHEYDIVQDLRFIGVNTEQGAMHGGFAKGYDSMHDQVVELLERYQTKRVWLTGHSLGGGLAVVCAYRLLEGTTYPIAGMMTFGQPKVVRSQLVEYLGPKLIGKYVFFVNDMDPVTRVISPYEHFGHMVRWNDNDIERSQMLLMSAGADSPAAGQEAGYIEGMTQADFQELLRSVEESNTPKFDENGNQLVQGFVPNVFDHYLDAYREMLEQLRTHSNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IT54</accession>
    <name>A0A518IT54_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_22250</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="67" mass="7705" checksum="68400ECF04441F4C" modified="2019-10-16" version="1">MPRTPPMSGEFFDCADHALMAFQIWRRMGRNNESTGAAWRRMMESDCPTQDVMALVAFHVFYGMGNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IT55</accession>
    <name>A0A518IT55_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_22510</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="79" mass="9012" checksum="66C2EB7D4272D87A" modified="2019-10-16" version="1">MPNFDGQNRGSMTDQISHNLFADLPTSLTEELVNVLAENPQVRIERIVSTGQFTKPGFWYDQDEHEWVVVLKGPRKVAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITF7</accession>
    <name>A0A518ITF7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">stkP_2</name>
        <name evidence="8" type="ORF">Mal33_23560</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036410">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57938">
        <property type="entry name" value="SSF57938"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="28"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="57"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV56367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="446" mass="51138" checksum="B82486820B8E1459" modified="2019-10-16" version="1">MVSNRPKATWIFDCCTWMIKSRQKLGKYQIEKKLGEGGFAGVYRALDTIEGVRVALKIPYSQSLSSDTLEECLKEVRMMASLDHPHILSLKNAEFIEGHFVLAFPLAEQTLGDRITKRMSMAQGISYTEQMLEAVSYAHQRRIIHCDLKPENMVLFANGDLRLTDFGIAKIAMRTLRASGSGTVGYIAPEQAMGRPSFRSDVFSLGLVLYRVFSGKLPEWPFAWPPPNYRALCDRVSPEFVEMLRRSLQMEPQRRYRNATQMLSAFRRLKARAILNNEATANAGKKKKTGRDWRTLRYQQFLRNYGKVIDVNGSCKKCKGPVAESMIACPWCSSDRQMHVRETRFPQVCPRCEGGMKLDWSFCPWCEGPEFELGSTRSFTDKRYTTSCDNEECGGRLMPFMRFCPWCDTRVQRTWNLTGSKDKCRSCGWGVSREFWSCCPWCATDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITM6</accession>
    <name>A0A518ITM6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acetylornithine deacetylase</fullName>
            <ecNumber evidence="3">3.5.1.16</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">argE_2</name>
        <name evidence="3" type="ORF">Mal33_24340</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.5.1.16" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008777">
        <property type="term" value="F:acetylornithine deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001261">
        <property type="entry name" value="ArgE/DapE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00759">
        <property type="entry name" value="ARGE_DAPE_CPG2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="M20_dimer" evidence="2">
        <location>
            <begin position="178"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="384" mass="41620" checksum="4E42363C008BFD49" modified="2019-10-16" version="1">MSPVVDLTSDLIRFPSVSHRCNEDVAAFIQQRLDRLDFTTERVSYIDPAGVTKVSLVARRGEGVGGLAYFAHNDVVPVDDWQGPGSNDPFDPIIDGGRLYGRGSCDMKGSLAAMLIAAQSVTAAQQQAPLWIVVTADEETGFGGARNVVDQSQLYRQMVEQQPVAVIGEPTSLDIVHAHKGIDGFRLTSRGKAGHSSSRDGVNATLPMISMLQLLKSIHERTQSDPTLQDSRFDPPDLSWNIGITGGGTAINVTPAKCQAWGSLRTMPGIDGSELVAQVQAKADELGIVFQRINGCGPMWIDPDAPFVREMVELTGSEKSKTVCYGTDAGIFNSFKQMVVCGPGDIAQAHTVDEWIDLQQLDRGVEVYRQVIQRWCCATSSRQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITN2</accession>
    <name>A0A518ITN2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_24350</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="SSF46565"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="198"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="233"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="527" mass="56250" checksum="CB3B6A3ED1CA5779" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITN7</accession>
    <name>A0A518ITN7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Serine endoprotease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_24440</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13180">
        <property type="entry name" value="PDZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDZ" evidence="2">
        <location>
            <begin position="103"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="339"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="398" mass="43820" checksum="3DB61C7EDC228D66" modified="2019-10-16" version="1">MLIMKIAATSHVLRVEWDDQSLRFSGVQPMKNAFLHRLNLDPHRSTIRSTAALRKASSSGRVLSGALLLCLAPLTIAQEIETPQVIPTPSVQLPPKPVDSTLLNDLQPAKKPRLGLVVEDLTPQLAKHLRTDRGVYVASVEQDGPADVAGVRSGDVIVRVGETEVASITDLMAAVAKIDGETISLTLEGEKGRRTAEVKPVMVAEEPIELMDLDEFEDSAPGDRDPLITGDLIRQLMNEFGQSLDGRTLRDLGGLADQLLNDNLGQNQPLMDRQLKITIDRRGDDPAEIFVELDGEQYKTDAKHLDQLPQELRATIAELVGAPRTGKSFRFGGIHIDLDGQRPRSIDPPSLKQPKAPRGFEPLDEESAAPSQIDELRRELNELRRKLDRIQPNPGDFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITU2</accession>
    <name>A0A518ITU2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_24700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="224" mass="23729" checksum="E104CF2C4A6D61D4" modified="2019-10-16" version="1">MCPYSFCPIGNTQRSVSDSPGLTMIAGSMKNEQSDVKSHREKSIVCDRLRSAAITVRCGGIDPPLFDVTCGTVRCSPNPNNTRSRPPVFWMMQLALSSAIRIVRSTTSCGDSRHCLTVSSSIVNAFSLLAMNCAHCEALSAAALPALICHAAITTATTAPIAAIAHCTTHPKLSLSFIESGSICIASVGESASRLLFSRESKTIAIPGRLNLLQMVKKGCARGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITU3</accession>
    <name>A0A518ITU3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phage portal protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_24970</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006944">
        <property type="entry name" value="Phage/GTA_portal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006427">
        <property type="entry name" value="Portal_HK97"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04860">
        <property type="entry name" value="Phage_portal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01537">
        <property type="entry name" value="portal_HK97"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="408"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="517" mass="57247" checksum="2B7B8025501E7E24" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IU56</accession>
    <name>A0A518IU56_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FHA domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_26160</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd00060">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SSF49879"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="1">
        <location>
            <begin position="148"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="FHA" evidence="1">
        <location>
            <begin position="233"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="317" mass="34631" checksum="CAACD277A0FBF0F5" modified="2019-10-16" version="1">MNDYDVYHQWLGIPPEDQPPTLYDLLGVACFERDLDVIRRAAGHQSMQVRRLAEGEFAELGCRLLNEIAEARLCLINPARREAYDLALITGGTVPAGTVLPTAKSKSAKMLAKGSVKGTVEEIVPTSMEAIYINIAPMLAGQPRQNRWVIGYDPKCDFRIDSPVVSSIHCEVIYTSEGAAIADLNSTNGTYVNQKRIHSPHSVRRQDLITLGRDKRILLPGHLMAGEDSHGAIFVGKGAGNEIQLESPTVSLFHARIIPSGTAATVEDLHSKNGTFLQRGDGKPIRIQRCRLHVDDTLYFGSVSVQAHRLLTACGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IU80</accession>
    <name>A0A518IU80_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_26350</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021889">
        <property type="entry name" value="DUF3500"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12006">
        <property type="entry name" value="DUF3500"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="320" mass="35349" checksum="43C5D0F094951646" modified="2019-10-16" version="1">MTRQPNAIDRRSFVRIASAATVAVPLAGSIARFAHGAPAARQPAESAVGELYASLSEAQRGEICFDFNHSKRSEISANWHVTKHKIGDTFYSDKQRDLIDRVIRGVTSEDGYERFQRQMTSDHEGVHNYAIAIFGDPSTDQFQWELTGRHLTMRADGNSVPGAAFGGPLVYGHGVGNPKRSLFGYQTAVANEVFKSLDADQAKAALLEGFPGEWEVELQGSEGKFEGVAVADLSGEQKQLVEQTLRTIIAPYRETDVEEAMSILNTNGGVDQLRMAFYQDEDLLNDKVWDLWRIEGPNLVCHFRGAPHVHAYINIGVKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IU85</accession>
    <name>A0A518IU85_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">BFD-like [2Fe-2S] binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_26310</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007419">
        <property type="entry name" value="BFD-like_2Fe2S-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041854">
        <property type="entry name" value="BFD-like_2Fe2S-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04324">
        <property type="entry name" value="Fer2_BFD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fer2_BFD" evidence="2">
        <location>
            <begin position="8"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="88" mass="9979" checksum="41D43EFE73420073" modified="2019-10-16" version="1">MELDDELCLCFHVTKRKVVNFIRIRKPVKASQLSECFGAGTGCGWCRPFLQRLLEQSAQQIEQPDDGLPDTDAYASGRQQHRKNKGLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUA6</accession>
    <name>A0A518IUA6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Undecaprenyl-phosphate mannosyltransferase</fullName>
            <ecNumber evidence="2">2.4.1.54</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_26510</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.4.1.54" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047267">
        <property type="term" value="F:undecaprenyl-phosphate mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="37"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="267" mass="28851" checksum="6D612F04FB71781F" modified="2019-10-16" version="1">MRRPNTMSQVTAINQAESAAVSAAANPIASHLQSVVVVIPALNEERSLPLVLGDLPDVGQVIVIDNGSTDRTADVARAGGAVVVNESQRGYGAACLRGLATIEQQVNDGRAAPDIVVFLDADYSDHPDLLPRLVAPIFMGQADFVLGSRLLGEREKGAMPPQSVYGNRLACFLMRLLFGARYTDLGPFRAIDYGKLCDLKMADENFGWTIEMQIKAIFAHLRYLEIPVPYRNRVGTSKISGTVSGTIKAGSKILYTVARYGLRRGSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUD0</accession>
    <name>A0A518IUD0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative transcriptional regulatory protein TcrX</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">tcrX</name>
        <name evidence="3" type="ORF">Mal33_27020</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13581">
        <property type="entry name" value="HATPase_c_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="7"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="332" mass="36353" checksum="41E1C1823935CF0B" modified="2019-10-16" version="1">MPDEPRLILVVDDSATQLAQMRMLLEKAGYRTLTADDGEQALSVAREHNPDLVVTDLEMPGMSGLDLVMMLNMESPQLPVVLTTSRGSEELAVEALQAGAASYVPKRNLAKDLADTIERTISVADSERQRLSFAKYIRTVAIELELTNDDTLLSQILARLEAPLVELGIVTEATRMHIGIALDEALRNAMIHGNLEVPSSLRDESCGQAYIDLIQARLKDEQYASRRVFVSLTANPEQAVFVITDQGPGFDVNSLPDPTDPENWEAVSGRGLLLIRSFMDEVQHNDAGNQITMVKLRVDPNAVDDDDDDCCDDDDCCGGEDCCSEPSDGQCD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUL5</accession>
    <name>A0A518IUL5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Mal33_27830</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005599">
        <property type="entry name" value="GPI_mannosylTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03901">
        <property type="entry name" value="Glyco_transf_22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="53"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="86"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="116"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="158"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="234"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="264"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="367"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="433"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="462"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="488"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="515"/>
            <end position="533"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV56784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="684" mass="74639" checksum="E7018BCD91DB525E" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUN7</accession>
    <name>A0A518IUN7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Hydrogen peroxide-inducible genes activator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">oxyR</name>
        <name evidence="4" type="ORF">Mal33_28060</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="3">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="298"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV56806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="320" mass="35526" checksum="D143DEF5628AF206" modified="2019-10-16" version="1">MQIRALRVFCDIASQRSFSRAAAAHGMTQSAASQIVHHLEQDLSVQLIDRSKRPLVLTAAGQLYFEGLQRVLFDLHTLDQEVRSFGKRLAGQVAVASIYSVGLSYMPSAKSEFAERHPDVDLHIEFVIPERVHESVMEGTADLGLISYPKSTRTLNCVTWQREPMKLISAPDHPFANRREVRLAELNGQLMMGFDPSLKVQREIAAYLTRNGIRPKFDTGFDNIDSLIRAIQLNSGIGILPEPAIRREVANDSLRVIQCPDLEITRPLGIIWRRGARLGPAALEFGALLLGRPLKPDESSAELRRRADAESKQPASSAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUQ1</accession>
    <name>A0A518IUQ1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_28220</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="272" mass="30017" checksum="49956EFA0AF5630A" modified="2019-10-16" version="1">MLMALLVFVGFFVFFMFMIWLLDRLNFRTGEVVVAIVEEAAGRGENAEGFERDFEPPGEEEVSELTEPTLTDTLQAVTDAVSSVAASLDSMNTDASASTTGSGQGDSRPPGPEGEGEDIIPRFERWNLKFQAKSMVAYAEQLDFYQIELGAIGGSTEGVDYASNLAKSPKKKHNPDTSTEKRLYFRFTQAGPLERWDKSLLGKAGVGVGAGRHVLKFIPPNLENILAHTELEYAKEKGYQSVTQIAKTIFESQPGGDGHHFVVIEQRYRKPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUQ9</accession>
    <name>A0A518IUQ9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Bacterial extracellular solute-binding protein, family 5 Middle</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_28170</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039424">
        <property type="entry name" value="SBP_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000914">
        <property type="entry name" value="SBP_5_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30290">
        <property type="entry name" value="PTHR30290"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00496">
        <property type="entry name" value="SBP_bac_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SBP_bac_5" evidence="1">
        <location>
            <begin position="496"/>
            <end position="611"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="804" mass="90235" checksum="E7CF6D7AE5171DAB" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUU9</accession>
    <name>A0A518IUU9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">barA_8</name>
        <name evidence="17" type="ORF">Mal33_28720</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00088">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036641">
        <property type="entry name" value="HPT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029151">
        <property type="entry name" value="Sensor-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008207">
        <property type="entry name" value="Sig_transdc_His_kin_Hpt_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01627">
        <property type="entry name" value="Hpt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00073">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103190">
        <property type="entry name" value="SSF103190"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47226">
        <property type="entry name" value="SSF47226"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50894">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 17" id="KW-0418">Kinase</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 17" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="15">
        <location>
            <begin position="321"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="13">
        <location>
            <begin position="420"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="14">
        <location>
            <begin position="657"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="14">
        <location>
            <begin position="797"/>
            <end position="915"/>
        </location>
    </feature>
    <feature type="domain" description="HPt" evidence="16">
        <location>
            <begin position="982"/>
            <end position="1079"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="919"/>
            <end position="944"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="10">
        <location>
            <position position="706"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="10">
        <location>
            <position position="846"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphohistidine" evidence="9">
        <location>
            <position position="1021"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="QDV56871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1084" mass="119437" checksum="72DC0ECAB8FC2013" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IV23</accession>
    <name>A0A518IV23_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NHL repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_29420</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001258">
        <property type="entry name" value="NHL_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01436">
        <property type="entry name" value="NHL"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51125">
        <property type="entry name" value="NHL"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="NHL" evidence="2">
        <location>
            <begin position="228"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="repeat" description="NHL" evidence="2">
        <location>
            <begin position="278"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="364" mass="40071" checksum="6A30F2482B0A7B3F" modified="2019-10-16" version="1">MRRIIHLFLPAERPGPIAKTMQTPAANRYVPPPQTPQSAGAASLGLPSRRKFVGQLAAIASAAVALPVAGCIDPPGASGAVDLVWGRRGLSEGRFQKPRAIAIDAEDQLYIVDTTGRIQVFSADGEYLRGWKTPDATNGRPTGLQVDDASRRLLVADTHYFQLLSYSLDGDLIESETLGGTQGTGPGEFSFITDAVRDSAGNYYTGEYSDIDRIQKFSPAGEFLMQWGSTGSEPGQFVRPQSLAIDRRDHLWVADSCNHRIQVFETSGPEPTLVRAWGEFGHQPGQLYYPYGITLGEESDCIYVCEYGNDRIQKFDLDGRSLEVWGRSGHAEGELFQPWGVVRDSRGRLHVLDSNNNRVQRVWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVA3</accession>
    <name>A0A518IVA3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_30180</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="34" mass="3426" checksum="1E80B575FB19A033" modified="2019-10-16" version="1">MGRRPSEIVTPRPEGAAICIAQGEALGAGKAFNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVA4</accession>
    <name>A0A518IVA4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Histidine--tRNA ligase</fullName>
            <ecNumber evidence="8">6.1.1.21</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Histidyl-tRNA synthetase</fullName>
            <shortName evidence="8">HisRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 10" type="primary">hisS</name>
        <name evidence="10" type="ORF">Mal33_30240</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + L-histidine + tRNA(His) = AMP + diphosphate + H(+) + L-histidyl-tRNA(His)</text>
            <dbReference type="Rhea" id="RHEA:17313"/>
            <dbReference type="Rhea" id="RHEA-COMP:9665"/>
            <dbReference type="Rhea" id="RHEA-COMP:9689"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78527"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.21"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3 8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.21" evidence="8"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004821">
        <property type="term" value="F:histidine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006427">
        <property type="term" value="P:histidyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00773">
        <property type="entry name" value="HisRS-like_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00127">
        <property type="entry name" value="His_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015807">
        <property type="entry name" value="His-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041715">
        <property type="entry name" value="HisRS-like_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004516">
        <property type="entry name" value="HisRS/HisZ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13393">
        <property type="entry name" value="tRNA-synt_His"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001549">
        <property type="entry name" value="His-tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00442">
        <property type="entry name" value="hisS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 8 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="9">
        <location>
            <begin position="1"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV57023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="445" mass="49079" checksum="ADF9B408359E00C7" modified="2019-10-16" version="1">MSLITPRTLRGFRDYLPEVMMPRERCMEIAREVFRSFGFAPIDTPALEYLEVLTGKGSDETDRQLYQFTDQGNRQVGMRFDLTVPFARFAAQHINELGTPFKRYHIAPVWRGEKSQAGRYREFIQCDFDTIGTQSVAADIETPLVIHSLMLALGFEAFKIHINDRRVLTGLLEHLGIAEHSVLVLRALDKLAKIGADKVAQEMQDTAGVSESQARSVLALAEIDVDADDLYAQLSKITGENATAALGIERLQQMREGLAAAGVPASRVKLDLTIARGLDYYTGVIFETFLDALPSIGSVCSGGRYDNLAELFTKQHLPGVGASLGLDRLLAAMEQLEILPQVRTPAPVFIPYFDKGQLNAYLQLAATVRAAGIGVEVFPEPKKLGQQLKYADGRGFTLALIAGNQEFEAGTCQVKDLRDKSTTDVQWSADQPEPLLDAIRSKLKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVD8</accession>
    <name>A0A518IVD8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_30460</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="70" mass="7714" checksum="27DFB598EAA80510" modified="2019-10-16" version="1">MSTQASNNIKQKQALSVYTVMLIASALALLIACILLYYELKAYGDFPYWNTRDAQPASASIAPVLRTFLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVQ6</accession>
    <name>A0A518IVQ6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_31650</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1174" mass="131175" checksum="B09A9D03F585D186" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVW3</accession>
    <name>A0A518IVW3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Dna-J like membrane chaperone protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Mal33_32280</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3680.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029024">
        <property type="entry name" value="TerB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012430">
        <property type="entry name" value="TMEM43_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13416">
        <property type="entry name" value="PTHR13416"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07787">
        <property type="entry name" value="TMEM43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158682">
        <property type="entry name" value="SSF158682"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="9"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="261"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="295"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="322"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV57224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="493" mass="55070" checksum="F581E4F34E9C800D" modified="2019-10-16" version="1">MAHTQEDRWAMMLMGPALVLLTLPVLWQNETRFDYYRAAAATQAVDSLDDVAAGTLISLTGPMESGSAIPGEYVEAFPGFLTVNREAEIYSWYQPDFSRNTHYEMKWKSSVQNSADNAGVKQECKSKSFYRAEYQVGELPIQTSLIEFFDDYDTIAPKTLRLKPTGMQLHLKPGSEYFHLTKKASDGLGNERVRYTGIPVPRVATYFGKYESGHGVADQSHHQSGIVYQMIQDSGNLHCIVAGDRPAALAKIKSHLQQLKWIIRGLGTAAIIMGFAILFSSITGFMYHLPLIGPLAGWGSFLAAVIIGLTVAILNIAAAYLVAHPLLLAIIATGIVATIYLMRKRGKASQQTLRRDLIQRYGHSLGTDELKELEFLELAQMAMSDAQLDDNETKILQKWAKKHRWDQAKYDAMIARARSERASSDSVPADDEHLRNVVRLAMADGTLTGYEIRTIRAVSKRLGFDDTTIREMIDRVRRDIARNRAEAQSHPTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IW18</accession>
    <name>A0A518IW18_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5 7">50S ribosomal protein L16</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 10" type="primary">rplP</name>
        <name evidence="10" type="ORF">Mal33_32840</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 7">Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 7">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uL16 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01433">
        <property type="entry name" value="Ribosomal_L16_L10e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01342">
        <property type="entry name" value="Ribosomal_L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016180">
        <property type="entry name" value="Ribosomal_L10e/L16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036920">
        <property type="entry name" value="Ribosomal_L10e/L16_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000114">
        <property type="entry name" value="Ribosomal_L16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020798">
        <property type="entry name" value="Ribosomal_L16_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12220">
        <property type="entry name" value="PTHR12220"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00252">
        <property type="entry name" value="Ribosomal_L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00060">
        <property type="entry name" value="RIBOSOMALL16"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54686">
        <property type="entry name" value="SSF54686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01164">
        <property type="entry name" value="rplP_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00701">
        <property type="entry name" value="RIBOSOMAL_L16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 7" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="5 7" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L16" evidence="9">
        <location>
            <begin position="5"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV57280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="138" mass="15341" checksum="97D4A8C1A58E64B8" modified="2019-10-16" version="1">MALMPKRVKHRKSQRGRIKGSATRGNTVVFGDFGLQSLEPGWIRAQTIEAGRIAAQQYVRGEGTLYIRLFPHRSITSTPLETRMGKGKGEPEAWVAVVKPGTILYELGGVTEQQAKVCFARLASKMPVKVRFVSRRAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IW21</accession>
    <name>A0A518IW21_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">30S ribosomal protein S19</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">rpsS</name>
        <name evidence="7" type="ORF">Mal33_32870</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uS19 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00531">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020934">
        <property type="entry name" value="Ribosomal_S15/S19_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002222">
        <property type="entry name" value="Ribosomal_S19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005732">
        <property type="entry name" value="Ribosomal_S19_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023575">
        <property type="entry name" value="Ribosomal_S19_S15_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11880">
        <property type="entry name" value="PTHR11880"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00203">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002144">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00975">
        <property type="entry name" value="RIBOSOMALS19"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54570">
        <property type="entry name" value="SSF54570"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01050">
        <property type="entry name" value="rpsS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00323">
        <property type="entry name" value="RIBOSOMAL_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV57283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="88" mass="9909" checksum="7CFDC27CD013A6C9" modified="2019-10-16" version="1">MSRSSKKGPFVDPKVFAKVQKQLEGGKKEPIKTWARACTIVPEFVNLTFMVHDGRKHMKVLVSEDMVGHKLGEFAPTRTFRGHGGKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IW57</accession>
    <name>A0A518IW57_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Enamine/imine deaminase</fullName>
            <ecNumber evidence="2">3.5.4.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">yabJ</name>
        <name evidence="2" type="ORF">Mal33_33200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.5.4.-" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02199">
        <property type="entry name" value="YjgF_YER057c_UK114_like_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013813">
        <property type="entry name" value="Endoribo_LPSP/chorism_mut-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14588">
        <property type="entry name" value="YjgF_endoribonc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="SSF55298"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YjgF_endoribonc" evidence="1">
        <location>
            <begin position="5"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="154" mass="16175" checksum="29A09C90DE75C828" modified="2019-10-16" version="1">MSAEANLEKLNLELPPAPKPAGVYKPCVIVGNMAYLSGHGPLKPDGNLIVGRLGEDMDLEAGYAAARQVGLTLLASIKANLGSLDRVKRVVKALALVRCTDAFDQQPAVVNGFSELFREVFGEEFGVGARSAMGTNALPGGIAVEIEVILEIEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWH7</accession>
    <name>A0A518IWH7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_34150</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="185" mass="20257" checksum="AA5C9F9FE38B6B4F" modified="2019-10-16" version="1">MPGACAARLYAIAAPRLRRNGNRWLGKTVVRRDSPFAWGLRHQALRDRRSAAENRASAVTRFFKLRSSDRIKPGGASPRIPRRQYVSTCPGIQIAHTDTPTSTPPQPRSGGRIKPGGASPRLPRRQCVSTRPGMQNAHTDTPTSTPPQPRSGGRIKPGGASPRFANRQCASTRRDSQIPHSQARD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWI7</accession>
    <name>A0A518IWI7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_34690</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="474" mass="53423" checksum="FDF21EEEC50B64A8" modified="2019-10-16" version="1">MHLSPRIPTSEPIDTHQKALQVNLDPRRYGTFAEIGAGQEVVRWFFRVGGGAGTIAKSMSAYDMKVSDAIYGRASRYVCRERLQAMLDYEHKLNLDRLKDVRGDTTAFFAFADTVSARNFQGTNDCHGWIGVKFQAHPRDDDSQIIIHVRMLDNEAALQQEALGIVGVNLVHGAFALNHEPELLVDSLLDGLSTSRIEIDMIEFSGIAFRHVDNRLMSLKLVELGLTGAAMFAANGDVLQPSEFFHRKPILVERGSFRPVCNVNLDMLHCAHEKFTQLPSVQGKEVAQVMEITMRNLKAEGEIDLRDFLARADVMSACGMTVLISDYFQYYRLASYLSRYTKESIAITMGAASLLDLFDEKYYAGLEGGILESFGRLFKNDLKIYCYPLRDQTTGEMTTCENLEIKPELQKLYGYLKDRGGINDLDNFNSDCLNIFSRDVLCKIKQGDMSWETMVPPPVADVIKSRSYFEYQAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWI9</accession>
    <name>A0A518IWI9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_34720</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041916">
        <property type="entry name" value="Anti_sigma_zinc_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="147" mass="15987" checksum="44E2BC208E73BD1B" modified="2019-10-16" version="1">MNRPQTSSDDWQPCEPGTLQRLADRQRRGRRIAATKRIAVPVAAVALLFVVGLSFTRRDQPAHQPHGGLSCAEFARHIHAYAENQVDATLAGQMHQHALDCPRCQQKLDALRDAAATRFPAAAPGLPLPLGPITDGGRDLLALTESR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWX5</accession>
    <name>A0A518IWX5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative adenylyltransferase/sulfurtransferase MoeZ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">moeZ</name>
        <name evidence="2" type="ORF">Mal33_35870</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Rhodanese" evidence="1">
        <location>
            <begin position="24"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="116" mass="13001" checksum="4E6F3944EC7C15CB" modified="2019-10-16" version="1">MQSPEHEALPIEVDVATVKSMLDQNADFVLIDCREADEYQVAKIDGSILIPLSELQEKGAELEAHRDRHIIVHCHHGGRSMRLTQILLANGFPRVQNMAGGIDVWSQQIDSSVPRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IX31</accession>
    <name>A0A518IX31_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Flagellin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Mal33_36480</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Secreted</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Bacterial flagellum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the bacterial flagellin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009288">
        <property type="term" value="C:bacterial-type flagellum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001492">
        <property type="entry name" value="Flagellin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046358">
        <property type="entry name" value="Flagellin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010810">
        <property type="entry name" value="Flagellin_hook_IN_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001029">
        <property type="entry name" value="Flagellin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42792">
        <property type="entry name" value="PTHR42792"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00700">
        <property type="entry name" value="Flagellin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07196">
        <property type="entry name" value="Flagellin_IN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00669">
        <property type="entry name" value="Flagellin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="6" id="KW-0966">Cell projection</keyword>
    <keyword evidence="6" id="KW-0969">Cilium</keyword>
    <keyword evidence="6" id="KW-0282">Flagellum</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Flagellin_N" evidence="4">
        <location>
            <begin position="18"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="Flagellin_C" evidence="5">
        <location>
            <begin position="570"/>
            <end position="650"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV57635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="650" mass="67906" checksum="7FABF7FF97D5D866" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IX63</accession>
    <name>A0A518IX63_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MMPL family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Mal33_36950</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004869">
        <property type="entry name" value="MMPL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000731">
        <property type="entry name" value="SSD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03176">
        <property type="entry name" value="MMPL"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50156">
        <property type="entry name" value="SSD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
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    <sequence length="751" mass="80921" checksum="B60D7BDBC1FB4910" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
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                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
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        <subcellularLocation>
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            <topology evidence="1">Multi-pass membrane protein</topology>
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    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0187 family.</text>
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    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
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</entry>
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    <name>A0A518IXT0_9BACT</name>
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        <lineage>
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            <taxon>Planctomycetia</taxon>
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Boedeker C."/>
                <person name="Pinto D."/>
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                <person name="Kohn T."/>
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                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
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        <location>
            <begin position="3"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
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    </evidence>
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            <dbReference type="EMBL" id="QDV57893.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="231" mass="26034" checksum="4C656F0BE9F0F1CB" modified="2019-10-16" version="1">MEQTLAERSYDYIRNKLACGDLAPGMRLVNRVLASEIGVSVIPVREAIHRLASEGLIEHVPGSGAFVRKSDPQAIDDLYVLRDALESCAAGEAALHITEFQIDELVSILDEALELAKQITQSRKQHATKTQMIAWLATEQRFHELVFEAARNQLLAKVAQEHRAIGQIFDAQRDNPQLLTSDVANQTCAGKSELIKAFRQRDQRKARELMSEQIQRGRKEVMRHIRAATKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYH3</accession>
    <name>A0A518IYH3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">PEGA domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_41410</name>
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    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
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                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013229">
        <property type="entry name" value="PEGA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08308">
        <property type="entry name" value="PEGA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="domain" description="PEGA" evidence="3">
        <location>
            <begin position="31"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="131"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV58124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="174" mass="19075" checksum="05112EF46C55E300" modified="2019-10-16" version="1">MNGLGPRYYLSINLLVLGIVLACSGCVRRRLMVRTDPPGALVSVDNQVIGNSPAASPFVYYGTREIRVDRDGYETQTLRHKINAPWYQLPGIDFIAETLWPFEIRDERVIDTKLVPRVSEPADVIAGRADQLREQSRTGVATPLPPTAMPPTAVPLPPNSQTLPFGGVPAQVSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYS8</accession>
    <name>A0A518IYS8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Hydrogenase transcriptional regulatory protein hupR1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">hupR1_2</name>
        <name evidence="4" type="ORF">Mal33_42610</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013976">
        <property type="entry name" value="HDOD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014626">
        <property type="entry name" value="Sig_transdc_resp-reg_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08668">
        <property type="entry name" value="HDOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036883">
        <property type="entry name" value="RR_HD-GYP_mod"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51833">
        <property type="entry name" value="HDOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="2"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="HDOD" evidence="3">
        <location>
            <begin position="138"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV58243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="395" mass="42893" checksum="2CFB3D1A52DA8467" modified="2019-10-16" version="1">MRVMFVDDEPQILRAISRMLDCADIDWDFETASGGREAIGALQQEDVDILVTDMRMPGMDGAALLDHVSHEHPATSRIILSGQADRDTMYRAVLPMHQFLSKPCDAQTLRDVLTRTYSIRSLFGNDETHRIVCGISSLPTTPGLLERVVAEANSRNGSIQKLGGLIACDPGLTAKTLQLANSAMFGYNGGEYSATQAARALGIEAMQALVAMLEHSSSIESAPLPDFSFDSYVAHAQRVARVACKIAIKEGWSLQLQREVYTAGLLHDIGRLVSSNHAHTKSPLVAAGPASGNDHFWESDPAIDEISDQKLGAYLLGLWGLPEEIVQAVALHRQPTACPSDRTSAAAVVCAADCIAHEETDPWDDGEIQDCENLFSKLGLPGRLETWRTAVTEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYU8</accession>
    <name>A0A518IYU8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Amylosucrase</fullName>
            <ecNumber evidence="4">2.4.1.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ams</name>
        <name evidence="4" type="ORF">Mal33_42790</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 13 family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.4" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047669">
        <property type="term" value="F:amylosucrase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11324">
        <property type="entry name" value="AmyAc_Amylosucrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.400.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044077">
        <property type="entry name" value="Amylosucrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022567">
        <property type="entry name" value="DUF3459"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="Glyco_hydro_13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045857">
        <property type="entry name" value="O16G_dom_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11941">
        <property type="entry name" value="DUF3459"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aamy" evidence="3">
        <location>
            <begin position="123"/>
            <end position="555"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV58261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="668" mass="76936" checksum="70FE11E6F3A3380E" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYV3</accession>
    <name>A0A518IYV3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_42760</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="78" mass="8920" checksum="BF2EC911E999DE4E" modified="2019-10-16" version="1">MTLEFQSRLDSDEVFHHVANATRLATAAIANDRLYDAPRTGMTGITRNPLANLSQLCIYRTIKVKQCRLRLTRLRCDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZB1</accession>
    <name>A0A518IZB1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Prolyl oligopeptidase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_44420</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="SSF53474"/>
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    </dbReference>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021842960" evidence="1">
        <location>
            <begin position="20"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S9" evidence="2">
        <location>
            <begin position="215"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="681" mass="76153" checksum="2A78953DF9D3E0AA" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZK6</accession>
    <name>A0A518IZK6_9BACT</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">Mal33_45510</name>
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    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetia</taxon>
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            <taxon>Rosistilla</taxon>
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    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="51" mass="5841" checksum="31BFF81534048B11" modified="2019-10-16" version="1">MCVDPKSENGYEVRRFQAARFASNLLHFSSESAQSVRPEVVGRRWPNQTSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
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    <name>A0A518IZM3_9BACT</name>
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        <submittedName>
            <fullName evidence="7">Putative sulfoacetate transporter SauU</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">sauU_1</name>
        <name evidence="7" type="ORF">Mal33_45650</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
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    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
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        <property type="protein sequence ID" value="QDV58542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
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            <end position="95"/>
        </location>
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        </location>
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        </location>
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        </location>
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        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
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            <dbReference type="EMBL" id="QDV58542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="431" mass="46266" checksum="0C7998F479DDBEB0" modified="2019-10-16" version="1">MLQQPTTIRYRTMAWLTIASGLAYLCRNAIGVAESSVREDLGLTLQQSGWFLGAFFWSYALFQVPCGWFAQRRGTRFALTLFAVGWSIAAFGLGVAPGFALLIIAQLIMGISQAGIFPAACNSIGHWFPMSRRTLACGILCAGMQVGAIAASGLTGVLLQSIDWRWVFILFSLPGIVWATGFAISFRDRPEQLEKVNDEELKLIHAHKTQRPDGTHAPIGEHKNDLGPPRTSAIIFLCGQQICRASGYMFFASWFPTFLQATRGVSIETSGFLQSLVLCGTLAGSLSGGFITDWIWQRTGSQRLSRSGMGSMALCVCGLLVLSAWLVSDVSLAIALLSLGSFFAALAGPPTFASTIDLGGTKVPQLMGLVNMCGNLAAAACPVLVGMLFEWTANWNLVLLLFAGIYLLGGVCWALVAPHAPSPRQPDASLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZX0</accession>
    <name>A0A518IZX0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative oxidoreductase YdgJ</fullName>
            <ecNumber evidence="3">1.-.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ydgJ</name>
        <name evidence="3" type="ORF">Mal33_46670</name>
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    <organism evidence="3 4">
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        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.-.-.-" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
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        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="11"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="GFO_IDH_MocA_C" evidence="2">
        <location>
            <begin position="155"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="398" mass="43474" checksum="98F3877379FEA527" modified="2019-10-16" version="1">MGINAPLNRKLRMGMVGGGQGSFIGRVHSIAACLDNRAVVTAGALSSNPERSKASAPDYAISEDRAYGSYEDMLDAESKLPDDQRIDFVSITTPNHTHFEVALAAVEAGFNVVCDKPMTFDLAQAEQLAKAVDQSDVIFALSHNYTGYPLIRQAREMIANGDLGEIQAIRSNYIQGWLRTRLEDSDQKQAAWRTDPTKSGAAGCFGDIATHAYNLGRYMTGLLPEQISCHLKTFEPGRKLDDYGTAVIRYENGALGTVTASQISHGRENDVTIEIDGTKGALQWRQENPNEMIVRANGQPHKIYTRDPNAPHTTAGAAAACRLPSGHPEGFFEAFANVYASAFDAMVARAEGGPIERVNTVYPNVNDGVEGMYFIQQCVESSKQDAAWLPMKHERARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZZ2</accession>
    <name>A0A518IZZ2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NAD(P)-bd_dom domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_46290</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="1">
        <location>
            <begin position="7"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="239" mass="26289" checksum="CB3B65662CE7C7EF" modified="2019-10-16" version="1">MTSLVVGASGATGKLLVEQLLLRGDRVRAIVRSSNKIPPSLLEHPLLSVIEARISDATDEDIAEYVDGCDAVVSCLGHNLTLRGIFGHPRQLVTRAVQRLSEAAMKKGASKPTKFVLMNTAGNSNRDLDERISFAEQCVLTLLRRAVPPHLDNELAAEYLRTAIAQNHSSIQWVVVRPDTLTDEADVSDYHPHASPTRSAIFNAGKTSRINVAHFMAELISNEDSWNRWKGQMPVIYNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J057</accession>
    <name>A0A518J057_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_47510</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="270"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="388" mass="43463" checksum="B544B0F1092C30CF" modified="2019-10-16" version="1">MSEYQYVVFRAIDRPLDDKQLAFAEKQSSRSELSRWEMSVEYHYSSFRGDVDGLLRRGFDLHLAYTNYGDREIRLRLPSGLPFPQSTITPFLTCGSFEWEQDAKGIGGILSVAPFHESGDIEEVWDFDDYLDSLAKVREQLIVGDLRALYLLWLCAAYDDNEDPEETIEPPVPHGLDNLPALSTSLLPFFGHDPLILKAAAKGVPGFDSNANGEDPIQDWSQSIPEARSRGLLQRFLKEDPVSVKAELLAEIRASGSVVDWPTTVRGRTLDELLDATVELREEANRIQEQKQQAKAKREAAKAEKERLARMEKMKAAPKTWLAEAEKTVNARGTANYKAAADILADLREAVGGEKGNQLARDCATKLAKAHPTLNMLKSALRKRGLFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0I0</accession>
    <name>A0A518J0I0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_48640</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the YjdM family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004624">
        <property type="entry name" value="YjdM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013988">
        <property type="entry name" value="YjdM_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013987">
        <property type="entry name" value="YjdM_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30305:SF3">
        <property type="entry name" value="PTHR30305:SF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03831">
        <property type="entry name" value="YjdM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08274">
        <property type="entry name" value="YjdM_Zn_Ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00686">
        <property type="entry name" value="phnA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YjdM_Zn_Ribbon" evidence="4">
        <location>
            <begin position="4"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="domain" description="YjdM" evidence="3">
        <location>
            <begin position="46"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV58839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="113" mass="12267" checksum="D4E98AB3BDB7B024" modified="2019-10-16" version="1">MSDLPNCPECDSEYTYEDGILLICPSCAHEWTANQAEDDQQQEPGVRDANGNALQSGDTVTVIKDLKVKGTSLVVKVGTKVKNIRIVDGDHDIDCKIDGVGAMQLKSEFVKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0L0</accession>
    <name>A0A518J0L0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Quercetin 2,3-dioxygenase</fullName>
            <ecNumber evidence="5">1.13.11.24</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">yhhW_2</name>
        <name evidence="5" type="ORF">Mal33_49060</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the pirin family.</text>
    </comment>
    <dbReference type="EC" id="1.13.11.24" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008127">
        <property type="term" value="F:quercetin 2,3-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012093">
        <property type="entry name" value="Pirin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003829">
        <property type="entry name" value="Pirin_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041602">
        <property type="entry name" value="Quercetinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43212">
        <property type="entry name" value="PTHR43212"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02678">
        <property type="entry name" value="Pirin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17954">
        <property type="entry name" value="Pirin_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006232">
        <property type="entry name" value="Pirin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pirin" evidence="3">
        <location>
            <begin position="20"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="Pirin_C_2" evidence="4">
        <location>
            <begin position="157"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV58881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="243" mass="26998" checksum="4CD2A133A3949949" modified="2019-10-16" version="1">MTTPILYRPETMITLRKSNERGRADLGRLKSYHTFSFASYHDQAHMGFRALRAMNEVCVAAGHGFGRHAHANMEIVSYVLDGTLELKDWMEEGEVVQAGELQRISAGTGISHSEINPSENQSAHFYQVWLLPKVRDVRPSSERRRFDDGEMKNSLRVVASPDGRDGSLSIQQDALLYLSKLESGATLDFAIDAGRYAWLQVLRGSVALNSNHLETGTGAAIENESLLRIDATSDAEIMLFDLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0L1</accession>
    <name>A0A518J0L1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ribosome biogenesis GTPase A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rbgA</name>
        <name evidence="5" type="ORF">Mal33_48930</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023179">
        <property type="entry name" value="GTP-bd_ortho_bundle_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019991">
        <property type="entry name" value="GTP-bd_ribosome_bgen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016478">
        <property type="entry name" value="GTPase_MTG1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006230">
        <property type="entry name" value="MG442"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03596">
        <property type="entry name" value="GTPase_YlqF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1 2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G" evidence="4">
        <location>
            <begin position="115"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="292"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="122"/>
            <end position="127"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR006230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR006230-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV58868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="318" mass="35320" checksum="D8F406EFDD2EBEF7" modified="2019-10-16" version="1">MPIQWFPGHMHQARLEMQAILPKVDLVIEVLDARIPYSSENPLLAELRGDKPCLKVLAKSDLADEAMTETWLSHFEQTVGVRAHAVTTDDVPTIRKLKQIAIRMLPHRRGQKINAMIVGIPNVGKSTIINFLAGRKIAKTGNTPAVTKHQQRVTIGDGFALLDTPGMLWPNVHNVNSGFRLALLGSVKETAMDYAEVGFFAAGFLGAHYPDRLAERYNLESIPTTELEIIEAIGRKRGCLGKMNLVDIDRASRILVTEVRSGGLGLLTLETPETMEEEKVKTAAAIAAKAEATKAKDAQRKKRFRDKQRAQRKSREME</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0L3</accession>
    <name>A0A518J0L3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_49050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="72" mass="7897" checksum="51BC568FF064D667" modified="2019-10-16" version="1">MPGFNRAGRESVKFSWPPMSTPNAYIGGIISGGLRLLRQLCRARLPRDSFALGRPATFAARCDDMPGGRDCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0R8</accession>
    <name>A0A518J0R8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_49200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51831">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD" evidence="1">
        <location>
            <begin position="28"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="206" mass="22814" checksum="744DAA57A771EE13" modified="2019-10-16" version="1">MNSEQAKQVEAVRRIVCQRMQGQGAGHDVDHVLRVHRVAREIQAEVGGNLFVIELAALLHDIGDAKFHDGKERSGEFSREILGELLVDPASIERVAEIVDTISFRKAADRATLSLEAQVVQDADRLDAMGAVGIVRTIEYGASVGQPFHIGEHADASERTGLGHFEDKLFRLAALMNTEPARRIASQRHDFMKQFVDQYLAECGQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0T3</accession>
    <name>A0A518J0T3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Na(+)/H(+) antiporter subunit B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">mrpB_2</name>
        <name evidence="9" type="ORF">Mal33_49750</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007182">
        <property type="entry name" value="MnhB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04039">
        <property type="entry name" value="MnhB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="35"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="68"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="113"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="MnhB" evidence="8">
        <location>
            <begin position="5"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV58950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="137" mass="14591" checksum="B1646F93DC188188" modified="2019-10-16" version="1">MDSVILKTAIRFLMPLILLSSVFLFLRGHNEPGGGFVGGLMASGAIVLYAITHSAAAARQVVRVPHRVLIGSGLLMSLCSGLLPLFLGRPFLTGMWTTITTTGFGEIHLGTPLLFDLGVFCVVTGVTLVFVFSLLEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0X4</accession>
    <name>A0A518J0X4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">2-acyl-glycerophospho-ethanolamine acyltransferase</fullName>
        </submittedName>
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        <name evidence="2" type="ORF">Mal33_50120</name>
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    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PlsC" evidence="1">
        <location>
            <begin position="32"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="201" mass="22921" checksum="8EE2FBD05BE64F36" modified="2019-10-16" version="1">MQLTSHAIVLLAKMFSGFTVRWVDCQPETCQRVYFANHTSHLDAAVLWSALPKEIRALTRPVAAKDYWDSSRFRRHIAESFNALLIDRKEIKVHQSPVQIMIREMGDVYSLIVFPEGSRSITGEMGSFKSGLYYLSKKRPDLELVPVYIDNVNRILPRGEFLPVPLLSCITIGAPMWLESGEPKNEFLARARDAVRALKDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1C4</accession>
    <name>A0A518J1C4_9BACT</name>
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        <submittedName>
            <fullName evidence="2">Cobalt-zinc-cadmium resistance protein CzcA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">czcA_7</name>
        <name evidence="2" type="ORF">Mal33_51720</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
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        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
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        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
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            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
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            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
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            <end position="483"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="495"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="529"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="562"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="613"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="990"/>
            <end position="1007"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1014"/>
            <end position="1036"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1042"/>
            <end position="1066"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1096"/>
            <end position="1118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1124"/>
            <end position="1146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1189" mass="129359" checksum="EF9BC76119D8BBC0" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1E6</accession>
    <name>A0A518J1E6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Copper-sensing transcriptional repressor CsoR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">csoR_2</name>
        <name evidence="1" type="ORF">Mal33_51750</name>
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    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
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            <taxon>Bacteria</taxon>
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            <taxon>Planctomycetia</taxon>
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    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <property type="project" value="InterPro"/>
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        <property type="evidence" value="ECO:0007669"/>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="92" mass="10399" checksum="5042ACA7AEEC362E" modified="2019-10-16" version="1">MLSDDEKKKLNNRLRRVIGQVEAVGRMIEDEEYCVDILMQLSAATGALNKVGQIVLEQHVKSCVSDAIQGGSAKDRDEKIEELMKVFRKYSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1S7</accession>
    <name>A0A518J1S7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Bifunctional protein MdtA</fullName>
        </submittedName>
    </protein>
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        <name evidence="3" type="primary">mtdA</name>
        <name evidence="3" type="ORF">Mal33_53200</name>
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    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Pirellulaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Aminiacid_DH-like_N_sf"/>
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        <property type="entry name" value="Methyl-teptahyd_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037089">
        <property type="entry name" value="Methyl-teptahyd_DH_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09176">
        <property type="entry name" value="Mpt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="SSF53223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mpt_N" evidence="1">
        <location>
            <begin position="18"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="2">
        <location>
            <begin position="126"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV59292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="281" mass="29393" checksum="BD928F44EA589622" modified="2019-10-16" version="1">MTKPKILLQFDTDSHASSFDAVVATDAGVDTLLQYGNVNTENVEGLVHGAMFTRGPEDLHRTAIFVGGSDVAAGEAVFERIEKCFFGPMRVSVMLDSNGANTTAAAAVLRAAKHLDLSQTTALVLGGTGPVGQRVARLLLQAGATVRLSSRQIDRARAVCDAIAARIDCGQRLSAVVGSEAIDGCDAVFACGAAGVQLLSADELAGSNVRLAIDLNAVPPVGIEGIDVMDRGKSRQDRIDYGAIGVGGTKMKIHRAAIQRLFESNDQQLDAEAIYAIGQTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1X1</accession>
    <name>A0A518J1X1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transposase DDE domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_53630</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002559">
        <property type="entry name" value="Transposase_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032806">
        <property type="entry name" value="YbfD_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01609">
        <property type="entry name" value="DDE_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13808">
        <property type="entry name" value="DDE_Tnp_1_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_1_assoc" evidence="2">
        <location>
            <begin position="12"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="DDE_Tnp_1" evidence="1">
        <location>
            <begin position="127"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV59335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="229" mass="24906" checksum="CB1F90A5E1FC9977" modified="2019-10-16" version="1">MKVPAAGSLLAILAAIPDYRGRKGRRHSLAAMLAAIICGLLTGAKRCTAIAQWLHDQEPEFWHSIGFTRKPPTSNCFRDVLLGLPPETLENAVRAWVTEYLAAVPGELRPVALDGKTLCGTLQPHGQSIHLLAMFDTATGGVIAQARMPGHTNEHKAAMRLLRSVVLKGRLVTGDAMFCQRDICRQITDSGGDYLVAVKDNQPELKETIESEFRSGRSPLQRTRSATAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J2C6</accession>
    <name>A0A518J2C6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_55240</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="179" mass="19491" checksum="69A93A0D7DEB3C22" modified="2019-10-16" version="1">MMSHNKVIGSTQWMLVTLVAVGMLSSLVILRAYGQEPTSPDADQKIQDSIRSALQGESSTAPAEEPLLGDVLDLIRRQGSILDGSTLDTEDDPKPEQAESNAVSDAHYRVAEMLLKTSRMLAALPGQDDLERQQLVRQMRREAAKCLQSGEPTPPGDVFFQPAGDQVAPLQFGDDTNEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J2F6</accession>
    <name>A0A518J2F6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_55520</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="69" mass="7694" checksum="9717A3E2F1339632" modified="2019-10-16" version="1">MSPIYSNPKNGTATTLPIEATWAELSERTDKADTSALAQWIEADLERIENQLSDFITPNTLKKSLRSGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J2F7</accession>
    <name>A0A518J2F7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_55580</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="131"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="372" mass="41023" checksum="9DB57CEB62329CBD" modified="2019-10-16" version="1">MLRLIAPRPGDGLCIARCTPDESERRSIAVPAIDPAATHGSGFHDLIQKNLSQADTWNMLANRSEIDSLVWGRSNRVCFPVGGPNRLRTMPDRPNMEVDLALTASVRCFGVLLLASNGFRDFAMRRLLKTLGLVLVFIATGLGAFTWWAARAAQQAPAFYKTAVASAPLALQHKEELQAQFEQLSQQVQIVGDWHATFTTDQINAWLASELANQFPNVLPPGTEDPRVSVEDGKVIVAARYRRGRIDSVISFELHAQLTDEPNVIALQIHRLRAGALPIPLQHFSDKISIAASRGDLEVRWENEEDDLIALVTVPSEHDRYVETPVVIETLELLDGEIVLAGRTGAKAHTAWIPDGPIYKLAKASTREISHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J2G3</accession>
    <name>A0A518J2G3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Segregation and condensation protein B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">scpB</name>
        <name evidence="5" type="ORF">Mal33_55590</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051304">
        <property type="term" value="P:chromosome separation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005234">
        <property type="entry name" value="ScpB_csome_segregation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34298">
        <property type="entry name" value="PTHR34298"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04079">
        <property type="entry name" value="SMC_ScpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00281">
        <property type="entry name" value="TIGR00281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0132">Cell division</keyword>
    <keyword evidence="2" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="223"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="270"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="20"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="284"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV59524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="384" mass="43509" checksum="34499C12F54C4067" modified="2019-10-16" version="1">MRPWGPRRGGWQDRNLFRPLESSATRRRRSTTRDAEASQTSSSSPAEDDDPKHKLQRTEAILVLSRGSLTTRKLAALAGLADATEARTLIRQLNQLYDQRGRAFRAEEIAGGYQLLTRPQFAPYLRRLGHVPQAVRLSSPMLETLAIVAYRQPVLRADIEAVRGVQSGELLRQLMEKDLVRISGRSDELGRPYLYSTTKRFLQVFGLRNTDALPCSQWFKEQPVDVPTTGTPDNLDPVLDSPDKESDVSIAIASSHHDASPEHTDAIVAVSSTESSVSNPPAAIIEDEEDEQWNDDDDDDDWDDEDDDWDDEDPDDDDDSDDDDDDWDEEEEADEDDDDDSKDDDWEEVDDDDDDDLEEADGEGDEWVDDEDDDDWDDDDEDEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ILX5</accession>
    <name>A0A518ILX5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycogen synthase</fullName>
            <ecNumber evidence="2">2.4.1.11</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_00410</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.4.1.11" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004373">
        <property type="term" value="F:glycogen (starch) synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="173"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="356" mass="38662" checksum="DF9B159DD4036017" modified="2019-10-16" version="1">MKIGIIGHLKFPMAKPFAGGLEAFTHGFVDALVARGHDVTLFAAGDSDPRLPLEPILPHATIPESLRRLGRVHDGWIDATEDEAYASLMTRLAAADFDLIHNHSLNPIPLRFASTLPTQMITTLHAPVLPRVDAELTSRPWQQCGRFVNISHANAMAWGRLVGDQTVIYNGIDTDFWKGRTTAEQPRAVWFGRIVPEKGTHLAIAAARRAGLPIDVVGPVSDQAYFDEFVAPSLGADCSYLGHKTHEQLSEIISSAAVAIITPCWDEPFGLVVAEALACGTPVAAFARGALPEIIAPSVGRLAYPGDVDDLALAIGEAIELNGEVCRRVAQERYSMDRMMNDYEALYRRVQLGVAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IM13</accession>
    <name>A0A518IM13_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">EcsC protein family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_00780</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024787">
        <property type="entry name" value="EcsC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41260">
        <property type="entry name" value="PTHR41260"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12787">
        <property type="entry name" value="EcsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="271" mass="28672" checksum="3C1810C7BFF374C7" modified="2019-10-16" version="1">MTNELIDNRLPDSAADELREAKRILEHHGIADRLTEMIGAPITASLRLLPDVAENAVYAAIDKSLNVALDVALRTLGDDAGKTGKPRLLTHKLLAGLSGAAGGAMGGATVAAELPVSTVLILRSVADIARSEGEDLSSVESRLACLQVFALDPGAKSEVDDDTEIGYFAVRAAMAKQIRDASQYVLKNGFADSAAPPLVKLVAQIGKRFGVVVSEKIAAQAIPVIGAVGGALINSYFIDHYQDLARAHFTIRRLERAYGQAVVREAYGTLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IM23</accession>
    <name>A0A518IM23_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_00920</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="128"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="178"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="261" mass="28831" checksum="ECDFA61111692F67" modified="2019-10-16" version="1">MVIGRRIDQVLEALKWPIGVFAVLMLGPLCYATLLFAARIWQHPWSLIWFVAGILAYAFAWRPFMRRWLKTDWMLTVEHELTHALFALLTGHRVKSFQVTRKGGRVEVVGGSNWLIALAPYFFPTAPLILLLFAILMPLGTLLPWTGLFLGFSMAYHVRSTWTETHGAQTDFDQAGRWFSLIFLPSANLCAIGLVASFAVGGWDGMQRFSSDASAAIQWLVMLVPSALTWPAENPPLLDPVPGIDPAATPPVAIGPDSAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IM39</accession>
    <name>A0A518IM39_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transposase for transposon Tn5</fullName>
            <ecNumber evidence="3">3.1.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">tnpA_1</name>
        <name evidence="4" type="synonym">tnpA_2</name>
        <name evidence="3" type="ORF">Mal33_01080</name>
        <name evidence="4" type="ORF">Mal33_01130</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.-.-" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.740.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038215">
        <property type="entry name" value="TN5-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003201">
        <property type="entry name" value="Transposase_Tn5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014737">
        <property type="entry name" value="Transposase_Tn5-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014735">
        <property type="entry name" value="Transposase_Tn5-like_N"/>
    </dbReference>
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        <property type="entry name" value="Dimer_Tnp_Tn5"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tnp_DNA_bind" evidence="2">
        <location>
            <begin position="8"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="domain" description="Dimer_Tnp_Tn5" evidence="1">
        <location>
            <begin position="378"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV54166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="474" mass="53364" checksum="6980BBA576395439" modified="2019-10-16" version="1">MQPTSIAYEFQDIQLGDKRLNDRAEALLASLAANPSASINEACSGWDETKAAYRLFDNPNVDPEAILGAHTEKTLQRIKAQDTVCIAQDTTELDYTAHPPEGVRNLDRLGRRGLYDHSHIAFTPEKLCLGVVGVKFYDRDKEALGTSKKREGQPLHTGEGQRWLDGYRKACEIAGKCPETQIVSLADREGDIYDIFVEADQHETPAQFVIRSQRKRSLPEKDPDGGPAAYKKMRAEIASAQPVAYREVQLPQTPERTKGSGNKQYPGREARTAKLEIRAKRMTLRAPHNKQSSMPPVEISVVWVSEIDGPGDGTEVDWLLLSSLPVDTIAQTLRIVDLYVARWPIEVFFRVFKTGCRVEEIQLEARDRLIRALMFYKVIAWRIMFVTFLGRECPELPCDVVFSEAEWKSVWKVVEKTAPPKQAPELSQFIPVLATLGGYNHREGDGPPGAEVIWRGTRRMLDFALCWQAFGPDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IM61</accession>
    <name>A0A518IM61_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_01140</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021870201" evidence="2">
        <location>
            <begin position="23"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="335"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="355" mass="40133" checksum="221FA86847CFEC3C" modified="2019-10-16" version="1" precursor="true">MKVLVCPQLLLMSMLMAAPVFAQVVPGTGTKIDYVGDDFEEPGWEFVHNMPKGSHENNERRNGPSGYSKNRRFIEGPERGQPDHMQIIPTPAGGLPHSKNALWVSTLHSGIPGQNTRTVEQDDLIVSCPSRLGTSFRPSESPNCMVRIYFPEADRWEKRNGPHFGFRLGCSTTAEQEREGFLAFGTEMGPEPYWPGIWVHYRHTADQRGPAGSAYLAVRGDNRGRDFRVAEMEQFGWWTFGISVTPDGRIHYYASPGVDPLTPQDLLTSQTPYGFNAERITSFFFNFCNVNDGRTWSTPVVIDDPEMYLVNASRVMQFVQRKEAAEAKRQAYAKRRAEMMAERNARSQNNSRSSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IM95</accession>
    <name>A0A518IM95_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Superoxide dismutase [Cu-Zn]</fullName>
            <ecNumber evidence="7">1.15.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">sodC</name>
        <name evidence="7" type="ORF">Mal33_01550</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.15.1.1" evidence="7"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004784">
        <property type="term" value="F:superoxide dismutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00305">
        <property type="entry name" value="Cu-Zn_Superoxide_Dismutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036423">
        <property type="entry name" value="SOD-like_Cu/Zn_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024134">
        <property type="entry name" value="SOD_Cu/Zn_/chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018152">
        <property type="entry name" value="SOD_Cu/Zn_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001424">
        <property type="entry name" value="SOD_Cu_Zn_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10003">
        <property type="entry name" value="PTHR10003"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00080">
        <property type="entry name" value="Sod_Cu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00068">
        <property type="entry name" value="CUZNDISMTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49329">
        <property type="entry name" value="SSF49329"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00087">
        <property type="entry name" value="SOD_CU_ZN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0186">Copper</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021770452" evidence="5">
        <location>
            <begin position="19"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="domain" description="Sod_Cu" evidence="6">
        <location>
            <begin position="92"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="116"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="119"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV54206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="226" mass="23516" checksum="AD388EFE5E0D3B5D" modified="2019-10-16" version="1" precursor="true">MKMRIYSCAALVALAVVGCEEPGDYTTPNAASPTSTDALPVDPITVDPVAVDPAANVPATNNPKTGDSAARVEQSTSAVAICELVPVGDSKVRGAVRFTQEGDVVKVRGEVTGLTPGKHGFHVHEKGDLSDKETGKSTGGHFNPTDQPHGKMTDEKRHVGDLGNIEANEEGIAMIKIDDSVISLKGEHSIVGRAIVIHAEADQFTQPTGDAGARVAFGKIENASAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMG1</accession>
    <name>A0A518IMG1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_02320</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="26"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="53"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="177"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="179"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="236" mass="26397" checksum="AD2595347130BC27" modified="2019-10-16" version="1">MPLSHYVYCMWPGLPEIWFRGRMSGLPAAICFAIAINTLLVSRFIYPQWLEPLMVRSVCWAFVGIWVVLFVRAVRGLPMLLAPRHASGEEDRYDAARTEFLKGRWFEAEALLVHCLEVDPRDALSLLLLASVYRKTDRFAAAAQTLDALAALETGDAWWLERDIEERRLKRMVDDLVAQQEDSETEEESESPADSEGSQTADAAKASSSTEENRPSDPTAEVAESPQMATAEGKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMJ0</accession>
    <name>A0A518IMJ0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_02350</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010869">
        <property type="entry name" value="DUF1501"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07394">
        <property type="entry name" value="DUF1501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="479" mass="53090" checksum="A0E0D03A44205790" modified="2019-10-16" version="1">MTNNNSDMQSSRRHFLASSAMRGGPLALACLMAQKASAEPKKPKMGTEGFDLKPKQPPLKPRATAMISMFMQGGPSQMDLLDPKPILNELHMQKFPGKIKYDNAAQASSKVFGSPWKFKKYGEHGTDVSELLPEFSTIVDDALVIRSMHTGVNNHGQSIYAMNGGRPLAGRPALGSWLTYALGTQSESLPAYIAMTDPKGLPVAGVLNWSNGWLPSLFQGTVIRPVKPRILNLQPPPHLDGEIQSNYLDLLQSLNRRHAEQRTGEHELQARIANFELAERMQFAADEATDLSRESKATHAMYGLDQPETREFGERCLIARRLVERGVRFVQLFTKNQYWDHHGGIVKALPASCKKIDKPAAALVKDLKQRGLLDSTVVHWGGEMGRLPVIQNEANIGRDHNTYGFTMWVAGGGFRSGMHGATDEFGHHAVEDQVNHFDYHATLLHLFGLEAENLTYEQNGREQSLIDGQPAKVIEKLLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMS8</accession>
    <name>A0A518IMS8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Malate-2H(+)/Na(+)-lactate antiporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">mleN</name>
        <name evidence="8" type="ORF">Mal33_03390</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018461">
        <property type="entry name" value="Na/H_Antiport_NhaC-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03553">
        <property type="entry name" value="Na_H_antiporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="66"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="108"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="147"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="187"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="238"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="287"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="336"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="374"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="412"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="504"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="527"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="domain" description="Na_H_antiporter" evidence="7">
        <location>
            <begin position="196"/>
            <end position="514"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV54385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="553" mass="58801" checksum="95CF8C77E5B5F9B2" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IN67</accession>
    <name>A0A518IN67_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Aspartoacylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_04840</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016811">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007036">
        <property type="entry name" value="Aste_AspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043795">
        <property type="entry name" value="N-alpha-Ac-DABA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04952">
        <property type="entry name" value="AstE_AspA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039012">
        <property type="entry name" value="ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV54529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="361" mass="39356" checksum="451CC694CBE70BD9" modified="2019-10-16" version="1">MSAAETQNWFGHDIAPGESLSTELVVSESYSSRNVSIPVNIRRGLQPGPTVFVTAALHGDELNGTGAIRTMLSDKEWSLQSGTVLMIPVLNMLGFERHSRYLPDRRDLNRCFPGSASGSMASRLAKVIFESLIARCDFGIDLHTAAVRRTNFPNVRADLSHPDCRRMAEAFGSGIILQTKGPKGSLRREATRAGCPTIIVEGGEVWKVESSVVECMTRGIFNVLMELKMMSGEPDIPDTQATIRETKWIRAERGGFLAMHVSPGDSIVKGQAIATNSNLLAEDQNRLEAPFSGIIIGMTTLPAVQPGEPVVHIGRLSNPKSVRRHEKQVAGDEVQRTAHEHLATNIQVVDAPAEDNNENVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INK6</accession>
    <name>A0A518INK6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Protease 3</fullName>
            <ecNumber evidence="6">3.4.24.55</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ptrA_1</name>
        <name evidence="6" type="ORF">Mal33_06230</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the peptidase M16 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.55" evidence="6"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001431">
        <property type="entry name" value="Pept_M16_Zn_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="SSF63411"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00143">
        <property type="entry name" value="INSULINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021699015" evidence="3">
        <location>
            <begin position="19"/>
            <end position="909"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M16" evidence="4">
        <location>
            <begin position="48"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M16_C" evidence="5">
        <location>
            <begin position="205"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M16_C" evidence="5">
        <location>
            <begin position="657"/>
            <end position="836"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF05193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV54668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="909" mass="101948" checksum="3BCF4F699B07747C" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INN5</accession>
    <name>A0A518INN5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 13">Dihydrolipoyl dehydrogenase</fullName>
            <ecNumber evidence="3 13">1.8.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">lpd</name>
        <name evidence="16" type="ORF">Mal33_06550</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>(R)-N(6)-dihydrolipoyl-L-lysyl-[protein] + NAD(+) = (R)-N(6)-lipoyl-L-lysyl-[protein] + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:15045"/>
            <dbReference type="Rhea" id="RHEA-COMP:10474"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="EC" id="1.8.1.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11 13">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="11 13">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="13">The active site is a redox-active disulfide bond.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.4" evidence="3 13"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004148">
        <property type="term" value="F:dihydrolipoyl dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006258">
        <property type="entry name" value="Lipoamide_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001100">
        <property type="entry name" value="Pyr_nuc-diS_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012999">
        <property type="entry name" value="Pyr_OxRdtase_I_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000350">
        <property type="entry name" value="Mercury_reductase_MerA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="SSF55424"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01350">
        <property type="entry name" value="lipoamide_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00076">
        <property type="entry name" value="PYRIDINE_REDOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5 11 13" id="KW-0274">FAD</keyword>
    <keyword evidence="4 13" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7 11 13" id="KW-0520">NAD</keyword>
    <keyword evidence="11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 13 16" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9 13" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="15">
        <location>
            <begin position="6"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="domain" description="Pyr_redox_dim" evidence="14">
        <location>
            <begin position="343"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="441"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="117"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="181"/>
            <end position="188"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="204"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="268"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="309"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="315"/>
            <end position="318"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="12">
        <location>
            <begin position="44"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012608"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="QDV54698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="463" mass="49124" checksum="F224357013C8D9FC" modified="2019-10-16" version="1">MNTAQHDLVVLGGGPGGYVAAIRAAQLGMNVACIDENERYGGTCLRVGCIPSKALLESSHLYHDAKTSFSNHGLKIGDVELDLPTMMNRKEKVVDTLTGGINMLLKKNKVTTYNGRGRFISSDTIEIEGKTPARVKAAKTIIAVGSRPMSFPSIEEDGVRIGNSTMALSFPEVPERLVVIGGGYIGLELGSVWNRLGSKVVVLEALDRILTGIDNELASIAKRTFTKQGLEFKMSTFVESAKVQGDLCVIKTKAGETIEADRVLLATGRVPSTDKIGLDAAGVATDKRGFLEVDANYQTSVPGIYALGDCIGGAMLAHKAMEEGVVCVERMTGMGSHFNYDVIPAIVYTHPEIAAVGKTEEQLKEAGIEYKKGMAPYGANGRAHTLGETEGRVKVLADAKTDRVLGVHIIGARAGDLIAEAGAAMEFGASAEDIARCCHAHPTLSESLHEAALGVDGRALHTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INR5</accession>
    <name>A0A518INR5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative subtilase-type serine protease</fullName>
            <ecNumber evidence="2">3.4.21.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_06940</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.4.21.-" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007280">
        <property type="entry name" value="Peptidase_C_arc/bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04151">
        <property type="entry name" value="PPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPC" evidence="1">
        <location>
            <begin position="115"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="510" mass="54211" checksum="EC894BEE43A91391" modified="2019-10-16" version="1">MDSLFPAGAGREATRTVTAAGTFSNWPPKVWVDREGLTVTPAKDKGKLEIAAGADAAGVYFIRLFDAEGASVVRPFLVDSLPAVDEVEPNNTPEQAQPIDGNAVVDGVLHKTGEVDRFAIPMKKGQTLVASLQAHNRLGSPMDAVLQVADPRGFVVAQNDDNVGNDPQIVFEAPADGTYSVGLFAFPATPNSTINFSGSKSYIYRLTLTTAGFVDHCSPMAIDTETDSAIQLHGWNIPDTAASVTPSAIPGERQFVAHPELASFVEVVRSNIPVFDPATHTEGAPIAWPVVISDQISAAGEVDKFAFDAKKGQTLRCRVESDSLGYLLDPVVTLFDEKGKQLAEVDDSSGRRDSELRHTIPADGRYELAVRDLYGNGGPRFAYRMTIDDSPPGFALTVAADSFVVKGKEKLTLPITVARERGCSDEIAVSIEGLPETLTATTATSAAKGATAKEVKLEISVSGEESLAFSGPIRVVGRIAGDKPREIAATFTVAGTEQTLDQIWLTAVKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INZ6</accession>
    <name>A0A518INZ6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Arylsulfatase</fullName>
            <ecNumber evidence="5">3.1.6.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_07650</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="PTM">
        <text evidence="1">The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.</text>
    </comment>
    <dbReference type="EC" id="3.1.6.1" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004065">
        <property type="term" value="F:arylsulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022160616" evidence="3">
        <location>
            <begin position="33"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase" evidence="4">
        <location>
            <begin position="39"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="modified residue" description="3-oxoalanine (Cys)" evidence="1">
        <location>
            <position position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR600917-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV54800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="464" mass="52000" checksum="56D1C0B0F3A831C1" modified="2019-10-16" version="1" precursor="true">MKPQTRWRRPILLALITFAAVGSFGLTRSSHAADTTTPPNIVMLISDDQAWGDYSFMGHDAIQTPNLDRLAKQSVLFRRGYVPTALCRPSLLTLINGRYASQHGVTGNDPSPKYSKPGTPENDQQRAQLISYLDRFPTVPQILGGDGYLSMQSGKWWEGNYKHGGFTHGMTRGFPQPGGRHGDDGLKIGRAGMKPVTEFIDMAVEEKKPFYLWYAPFLPHTPHNPPKRLLDKYTQAGRPASVAKYYAMCDWFDETCGQVIDHLDAKGLRENTLIVYVTDNGWIQDPNSSKYAARSKQTPYEGGIRTPIMFSWPGKLKPADREELCSSLDIVPTVLAAAGAEVPADLPGLNLMPGMTSGEKIDRQRIFGESFAHDIADIENPEASLLYRWCIEGRWKLLLTYDGEVNRYQTTHPRTERRPQLFDLIADPAEEKNLAAENPAVVKRLADAIEAWYPVTQRKTQTTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP10</accession>
    <name>A0A518IP10_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Planctomycete cytochrome C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Mal33_08080</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011429">
        <property type="entry name" value="Cyt_c_Planctomycete-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07635">
        <property type="entry name" value="PSCyt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021960680" evidence="5">
        <location>
            <begin position="25"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="6">
        <location>
            <begin position="23"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV54843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="579" mass="65070" checksum="12A91D31845CB520" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP27</accession>
    <name>A0A518IP27_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_07950</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="275"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="294" mass="33870" checksum="38A29D3DCA9163B0" modified="2019-10-16" version="1">MQMFFDWLSTLQWERLFPELLGKALGFLSGFAASWFLLFRKRLNALQRMQAGDSDDFIFQMHQLTPVDDASPATGSSDKYVLLFRNVAPKTTLNDLYDNIAVRDEINKLADQTTLSNPILQTDGTLGFEMLNDALGHIAGLLATTPFERQTWLFAMTCEDRQFVRKKCVRCFLIRPADLQRFADWNWCRDHLSVEKPWHWFRVVALHRIACVWQEEQKLAAEEAKSSRDKDMPLVDRQVRHDRVRMLSVGLHDGERPIDAPYQIDWSQHLPSLEKMGLPLAPATPPTDPPSDPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP57</accession>
    <name>A0A518IP57_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Riboflavin biosynthesis protein</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="11">Riboflavin kinase</fullName>
                <ecNumber evidence="11">2.7.1.26</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="11">Flavokinase</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="11">FMN adenylyltransferase</fullName>
                <ecNumber evidence="11">2.7.7.2</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="11">FAD pyrophosphorylase</fullName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="11">FAD synthase</fullName>
            </alternativeName>
        </domain>
    </protein>
    <gene>
        <name evidence="13" type="primary">ribF</name>
        <name evidence="13" type="ORF">Mal33_08170</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2 11">
            <text>ATP + FMN + H(+) = diphosphate + FAD</text>
            <dbReference type="Rhea" id="RHEA:17237"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <dbReference type="EC" id="2.7.7.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>ATP + riboflavin = ADP + FMN + H(+)</text>
            <dbReference type="Rhea" id="RHEA:14357"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57986"/>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.26"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 11">Cofactor biosynthesis; FAD biosynthesis; FAD from FMN: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 11">Cofactor biosynthesis; FMN biosynthesis; FMN from riboflavin (ATP route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the ribF family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.26" evidence="11"/>
    <dbReference type="EC" id="2.7.7.2" evidence="11"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00276">
        <property type="reaction ID" value="UER00406"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00277">
        <property type="reaction ID" value="UER00407"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="term" value="F:FMN adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
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    <dbReference type="GO" id="GO:0008531">
        <property type="term" value="F:riboflavin kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006747">
        <property type="term" value="P:FAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009398">
        <property type="term" value="P:FMN biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02064">
        <property type="entry name" value="FAD_synthetase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004821">
        <property type="entry name" value="Cyt_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015864">
        <property type="entry name" value="FAD_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023468">
        <property type="entry name" value="Riboflavin_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002606">
        <property type="entry name" value="Riboflavin_kinase_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015865">
        <property type="entry name" value="Riboflavin_kinase_bac/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023465">
        <property type="entry name" value="Riboflavin_kinase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22749">
        <property type="entry name" value="PTHR22749"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06574">
        <property type="entry name" value="FAD_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01687">
        <property type="entry name" value="Flavokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004491">
        <property type="entry name" value="FAD_Synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00904">
        <property type="entry name" value="Flavokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82114">
        <property type="entry name" value="SSF82114"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00125">
        <property type="entry name" value="cyt_tran_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00083">
        <property type="entry name" value="ribF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 11" id="KW-0274">FAD</keyword>
    <keyword evidence="5 11" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6 11" id="KW-0288">FMN</keyword>
    <keyword evidence="11 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="8 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Flavokinase" evidence="12">
        <location>
            <begin position="183"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR004491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="QDV54852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="307" mass="33293" checksum="A116761538606FA5" modified="2019-10-16" version="1">MTLIRDLDQASQVARGGAISIGNFDGVHRGHAVLLKQLRQLADEVGGPAVVLTFDPHPASLLRPDQAPVPLTWIERRADLLYRLGVDRVIACRPTAELLGLSATDFFQQVIRERLDCQAMAEGPNFYFGKDRQGDVEMLGQLCQRAAIPLRIVEPLDNQGQMVSSTMVRASIADGQIEAANAMLTAPYRISGLVAVGSQRGAGLGFPTANLSDLQVLAPAAGVYAGQTWVGGTAYHAAIHIGPNLTFDEGQCKVEVHLLDFTGDLYGERLEVQFNRRVRGIVKFASVDDLRNQLGRDIATVRNEPLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP86</accession>
    <name>A0A518IP86_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_08810</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="62" mass="6837" checksum="A4B5F9BE9E7ACB1D" modified="2019-10-16" version="1">MMEPPAPDGVDEAEEEALVANRRAYHRNKLATEAEAAEAAAKENFKVATAADWDTFGRRFAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPA7</accession>
    <name>A0A518IPA7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ECF RNA polymerase sigma-E factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rpoE_1</name>
        <name evidence="3" type="ORF">Mal33_08670</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014326">
        <property type="entry name" value="RNA_pol_sigma-70_Plancto"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02984">
        <property type="entry name" value="Sig-70_plancto1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="1">
        <location>
            <begin position="11"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="2">
        <location>
            <begin position="127"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="184" mass="20746" checksum="59EEBF7AECBC97A3" modified="2019-10-16" version="1">MNESEDVDRLQQYAPYLTALARAQLSPRYRAKVGVSDIVQQSMIQAYQAIDDFRGTTDVELRAWLRQILARNLIHVDRDLHRDKRNIDRERSLEDRLGQSSLCLEKLLAGSDPTPSQNIATSERVVQLAAALETLPEAQREAVRMHYLEGKKLSEVAGLLDRSTGAVAGLLHRGLKALREGMRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPG1</accession>
    <name>A0A518IPG1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_09540</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="834" mass="93105" checksum="3569EC4EF2B913E1" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPH2</accession>
    <name>A0A518IPH2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_09400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011453">
        <property type="entry name" value="DUF1559"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07596">
        <property type="entry name" value="SBP_bac_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="104" mass="10985" checksum="64541285E67A9ECB" modified="2019-10-16" version="1">MSITGRLNSTVDCCPAAASASGGVGFPALVGYAWGGRSSNSVSLDRTTERSIDERELCFSSRHRGGVQAVLVDGHVKFFAETIDPQIWSALGTRNNGEVIPDSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPR6</accession>
    <name>A0A518IPR6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Deoxyribodipyrimidine photo-lyase</fullName>
            <ecNumber evidence="2">4.1.99.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">phrA</name>
        <name evidence="2" type="ORF">Mal33_10360</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="4.1.99.3" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003904">
        <property type="term" value="F:deoxyribodipyrimidine photo-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036134">
        <property type="entry name" value="Crypto/Photolyase_FAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036155">
        <property type="entry name" value="Crypto/Photolyase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006050">
        <property type="entry name" value="DNA_photolyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48173">
        <property type="entry name" value="SSF48173"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52425">
        <property type="entry name" value="SSF52425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51645">
        <property type="entry name" value="PHR_CRY_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Photolyase/cryptochrome alpha/beta" evidence="1">
        <location>
            <begin position="22"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="493" mass="56431" checksum="3DBD752132A850D4" modified="2019-10-16" version="1">MTRIPELRIRDLNAKSVRPDGQFVLYWMIANRRTRYNFSLQHAASLAQELGRPLIVLEALRCDYPWASDRLHRFVLQGMADNRAALADANLRYYAYVEPSVGDGRGLIQQFARDACAIVTDDFPCFFIPAMLRLVSRQVDVAMQAVDSNGLLPIRATEKVFARAHDFRRFLQKNLKPHLSEMPKLAPLQGFRLSPPPPIPDAILERWPEATDAMLEASPEQLSALPIDHDVGPPAFDGGSVAAAATLDSFISQRLPRYGEGRNQPESDASSGLSPYLHFGQISTHDVFAAIVEREQWSPDRLAAKASGSREGWWGMSEEAESFLDELITWREVGFNFCVHRRDYDRYESLPDWAQQTLGEHADDEREFIYSLEEFEAAKTHDELWNAAQRQLVREGRMHNYLRMLWGKKILEWTPTPQAALQVMLELNNKYAVDGRDPNSYSGIFWVLGRYDRAWQERDVFGKIRFMSSENTARKLKVKKYLQRYAADASTAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPU0</accession>
    <name>A0A518IPU0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_10780</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="59" mass="6379" checksum="6AE7D20CB9A1235E" modified="2019-10-16" version="1">MQDVGLIGRGTLGGLADLRPIDQANGANRLGIDADAGGRGNAHRRELRFTILMLFDVRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQ30</accession>
    <name>A0A518IQ30_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Tyrosine-protein kinase wzc</fullName>
            <ecNumber evidence="11">2.7.10.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">wzc_2</name>
        <name evidence="11" type="ORF">Mal33_11760</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.7.10.-" evidence="11"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045226">
        <property type="term" value="P:extracellular polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009103">
        <property type="term" value="P:lipopolysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005702">
        <property type="entry name" value="EPS_synthesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003856">
        <property type="entry name" value="LPS_length_determ_N_term"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033756">
        <property type="entry name" value="YlxH/NBP35"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10609">
        <property type="entry name" value="ParA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02706">
        <property type="entry name" value="Wzz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01007">
        <property type="entry name" value="eps_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="11" id="KW-0418">Kinase</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="41"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="domain" description="Wzz" evidence="10">
        <location>
            <begin position="31"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="330"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QDV55206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="773" mass="84501" checksum="05F109D7E7E58819" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQ38</accession>
    <name>A0A518IQ38_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MurJ-like flippase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Mal33_11740</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029303">
        <property type="entry name" value="Polysacc_synt_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002797">
        <property type="entry name" value="Polysacc_synth"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01943">
        <property type="entry name" value="Polysacc_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14667">
        <property type="entry name" value="Polysacc_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="64"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="138"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="170"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="198"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="240"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="289"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
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    <feature type="transmembrane region" description="Helical" evidence="6">
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            <end position="382"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="394"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="419"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="452"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="domain" description="Polysacc_synt_C" evidence="7">
        <location>
            <begin position="366"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF14667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV55204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="520" mass="56735" checksum="3A77B371CEE17C6C" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQ47</accession>
    <name>A0A518IQ47_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_11840</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="47" mass="5594" checksum="B035A8C6B1BC25D6" modified="2019-10-16" version="1">MAATFTTVRYKEYWFTHKSELQVCQHQNDKHGHADLEFRSVLLALSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQ65</accession>
    <name>A0A518IQ65_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">prkC_3</name>
        <name evidence="5" type="ORF">Mal33_12040</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="4">
        <location>
            <begin position="63"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV55234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="543" mass="59846" checksum="676E2D60E7523A08" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQ86</accession>
    <name>A0A518IQ86_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glucose--fructose oxidoreductase</fullName>
            <ecNumber evidence="2">1.1.99.28</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">gfo_3</name>
        <name evidence="2" type="ORF">Mal33_12290</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.99.28" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047061">
        <property type="term" value="F:glucose-fructose oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GFO_IDH_MocA" evidence="1">
        <location>
            <begin position="7"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="372" mass="41086" checksum="6E748430CD697362" modified="2019-10-16" version="1">MHGNICRWGILSAAAIAKKNWDSIRNSGNGQVVAVASRSAEKAQAFIAACQASAPVPHEVDALGSYDDLLARSDIDAVYIPLPTGLRTDWVVKAANAGKHVMVEKPCGVTVDDVQRMIDACNANNVQFMDGVMYMHSKRMAEMRRVLDDGSSVGTIRRITSQFSFCAPEDWVQSNIRTGSDLEPAGCLGDLGWYTIRFILFAMNYQMPTEVRGRILHSVCRDESGQAVPMEFQGELHFEGGASASFYNSFRTNHQQLGHISGDKGYLQVNDFVLPFLGNTSSFEVANHNFVEDGCRFTMEQHSRQVGIAEYSNNAADAQETQLFRKFSELVLSGTRDPFWPKVSLKTQAILDAALRSANHEGRAETVPMFND</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQA7</accession>
    <name>A0A518IQA7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NPCBM/NEW2 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_12440</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.1060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013222">
        <property type="entry name" value="Glyco_hyd_98_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038637">
        <property type="entry name" value="NPCBM_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08305">
        <property type="entry name" value="NPCBM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00776">
        <property type="entry name" value="NPCBM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NPCBM" evidence="1">
        <location>
            <begin position="272"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="412" mass="44304" checksum="03D06AFC4E6106B1" modified="2019-10-16" version="1">MHRGVLAFCMAISLADIVPAEDLLLNSGLVAASFSDFESPDQLTFRDDKNQPLVVAADQLIRYGHEPIADFASGLMMVDGSWVVGRIERVSKDQVAIAGRYFRTTLSLTNVRAIALQLPTQPLARASILKTFTDADGGDDRLLNVSGDEIAGVLQFPPTIADAPLAFGATWKLRRGERTDAIAASTLRGIVLSPLLHPIRAAESGFWFGLDDGTRLAIRSIQRTDGAIELELASGESLAFAGDWDQFSAAVETIQPVRGATRWLSPQPALAFKQQASLSELQWPLATDSGLRGEPLTIAGYRYRHGLSMHANAQAAYRIPPDATRFQATVGMATDDDQSTATGSVVFQVLTADTTKAVRTQYTSPTLRPGDAPISLDIQLGDAKLIVLMVRDAGDGSSGDHAVWADARFLLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQF0</accession>
    <name>A0A518IQF0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Tryptophan synthase alpha chain</fullName>
            <ecNumber evidence="5">4.2.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">trpA</name>
        <name evidence="7" type="ORF">Mal33_12830</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + L-serine = D-glyceraldehyde 3-phosphate + H2O + L-tryptophan</text>
            <dbReference type="Rhea" id="RHEA:10532"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
            <dbReference type="ChEBI" id="CHEBI:58866"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="4.2.1.20"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 5">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 5/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Tetramer of two alpha and two beta chains.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the TrpA family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.20" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00044"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004834">
        <property type="term" value="F:tryptophan synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04724">
        <property type="entry name" value="Tryptophan_synthase_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00131">
        <property type="entry name" value="Trp_synth_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002028">
        <property type="entry name" value="Trp_synthase_suA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43406">
        <property type="entry name" value="PTHR43406"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00290">
        <property type="entry name" value="Trp_syntA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00262">
        <property type="entry name" value="trpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4 5" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="5 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="49"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV55312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="269" mass="29470" checksum="8B4A7A065D087D74" modified="2019-10-16" version="1">MSLLDETFAKLRSEGRKALLPFITAGYPDLDFTGDLLKDFGKAGVAACEVGVPYSDPVADGPVIQASYQRALESGFRLQQLFEMRKRIAAEVTIPTLTMASYAIIYRVGLERYIEQSQEAGFCGAIVPDLLVEEAAEFSKLCADRDFNLIQLVTPTTPRERQVRIAESSSGFLYFVSVTGITGERNELPPQLIDNVGWLREQTDVPVCIGFGISQPEHVAKLGPVADGLIVGSAIVRRIAQANAENRGEVRGEIDRYVREMLAAINAVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQJ5</accession>
    <name>A0A518IQJ5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cobalt-zinc-cadmium resistance protein CzcA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">czcA_2</name>
        <name evidence="5" type="ORF">Mal33_13420</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="AcrB_DN_DC_subdom"/>
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        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
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        <property type="entry name" value="CzcA/CusA/SilA/NccA/HelA/CnrA"/>
    </dbReference>
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        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82714">
        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00914">
        <property type="entry name" value="2A0601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="355"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="390"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="449"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="480"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="535"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="873"/>
            <end position="892"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="898"/>
            <end position="918"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="925"/>
            <end position="949"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="969"/>
            <end position="990"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="1002"/>
            <end position="1028"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1036"/>
            <end position="1073"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1036"/>
            <end position="1065"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV55371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1073" mass="118634" checksum="3929082E3E283746" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IR01</accession>
    <name>A0A518IR01_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">5-formyltetrahydrofolate cyclo-ligase</fullName>
            <ecNumber evidence="3">6.3.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_14910</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>(6S)-5-formyl-5,6,7,8-tetrahydrofolate + ATP = 5,10-methenyltetrahydrofolate + ADP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10488"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57455"/>
            <dbReference type="ChEBI" id="CHEBI:57457"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.3.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.3.2" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030272">
        <property type="term" value="F:5-formyltetrahydrofolate cyclo-ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002698">
        <property type="entry name" value="FTHF_cligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024185">
        <property type="entry name" value="FTHF_cligase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23407:SF1">
        <property type="entry name" value="PTHR23407:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01812">
        <property type="entry name" value="5-FTHF_cyc-lig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006806">
        <property type="entry name" value="FTHF_cligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02727">
        <property type="entry name" value="MTHFS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="12"/>
            <end position="16"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="142"/>
            <end position="150"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR006806-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV55514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="201" mass="22599" checksum="13FCAE75E4231E1F" modified="2019-10-16" version="1">MNLSANEIAERKDAIRKQAHANRKGQADKEAVSQRITDRLHQMSQYQNATAVMYYVDVRDEVRTRHALPEALASGKKIVVPFCVDGELELFHLESIDELETGMYKILEPRADLRQLAAKRVEVAELDLVIVPGVAFDQNGGRTGHGKGYYDKLLEHARADTPLISLAFECQMFPEIPVAQHDIYMDFVVTEDAVYAGRGRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IR05</accession>
    <name>A0A518IR05_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_15040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="162"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="308"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="347" mass="37794" checksum="3CF33F83F5D57755" modified="2019-10-16" version="1">MPESPLTKIVDFHKELLSMQRLGLPMELGFEGPPNALGSQLEQIQRRLALRIERQGDLIQAIASDPDLPKPYRSALSTWVQCEHPTEVLDQLSAAASARRDLHGQMGIALIGPLILVVVVYFGLISLCLVVAPRLEAIYAQMWLPVSGSLRLVGMLRDAMPIWVPGVPVLAILAIVWWSLRRGRSRFGWLFGGRRYFKSLQTAAYARHVAALLDVGCSTGKALASVGPLPLQSHDLGGELATANVYLSTAEEIGQQVPPDDPTIAALPPMLRWGLVGQLDGQSRSQVLREVAAIYSDAATSQARRWRVVLPMLLSGGIGGLLVLAYGLGLMLPYVDLLYKIATQITE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRQ5</accession>
    <name>A0A518IRQ5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase DDE domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_17490</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002559">
        <property type="entry name" value="Transposase_11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01609">
        <property type="entry name" value="DDE_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_1" evidence="1">
        <location>
            <begin position="90"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="459" mass="53386" checksum="3AA45D1C4BE31D3B" modified="2019-10-16" version="1">MAIMEDSLPAIKSFLPNTQVSAHFRSMLLRFLIAILTRHGRNSCMSAASAIEGKPRHRAQPGRFLKRYRQAIADLLTAITLKMLRDQDWNGRYLLLLDSTLVATAGQTVENTFSTGNSKRRPAKNRRYTKYKYQRKSCHCFVFALLLTPDGLRVPMWLPYYTKPYAKVHKIKHRTQAQLAAQLICDAQVPAGIELIVLGDTAFDAKCVRAACRERGYFWIVPVNTNRVFSAKKHGKRPRVSSRIEQLSASRFQTIRLAIGSGPYAAQRRASCHRTALRRDGTKSTRTYHVHSERSEVHNVGMVMLVFSSSKPIGKKIQREGTKLLMTNAKHLSARQVCELYSLRWQIELFFKELKSTLGMNQYSFKDFEAVESWMGSVLITFCYLEWTRRRKLADRRIDDRQRKCWKHARSYTVREALLLGIRYREHQWHLRRLKTNHGLRTLRKRYTELLSQEYRCLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRR7</accession>
    <name>A0A518IRR7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Imidazole glycerol phosphate synthase subunit HisF</fullName>
            <ecNumber evidence="9">4.3.2.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">IGP synthase cyclase subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">IGP synthase subunit HisF</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">ImGP synthase subunit HisF</fullName>
            <shortName evidence="9">IGPS subunit HisF</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">hisF_2</name>
        <name evidence="9" type="synonym">hisF</name>
        <name evidence="11" type="ORF">Mal33_17670</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8 9">IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + L-glutamine = 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate + H(+) + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24793"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58278"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58475"/>
            <dbReference type="ChEBI" id="CHEBI:58525"/>
            <dbReference type="EC" id="4.3.2.10"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 5/9.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 9">Heterodimer of HisH and HisF.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9 10">Belongs to the HisA/HisF family.</text>
    </comment>
    <dbReference type="EC" id="4.3.2.10" evidence="9"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000107">
        <property type="term" value="F:imidazoleglycerol-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04731">
        <property type="entry name" value="HisF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01013">
        <property type="entry name" value="HisF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006062">
        <property type="entry name" value="His_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004651">
        <property type="entry name" value="HisF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00977">
        <property type="entry name" value="His_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00735">
        <property type="entry name" value="hisF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9 10" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9 10" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="7 9 11" id="KW-0456">Lyase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="9">
        <location>
            <position position="11"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QDV55788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="261" mass="27701" checksum="2691F75BCA891018" modified="2019-10-16" version="1">MLAKRVIPCLDVSLGRVVKGTNFVNLRDAGDPVEVAARYEREGADELVFLDITASHEERDIIIDVVQRTAEQIFMPLTVGGGIRSLEDIRALLSAGADKVSINSAACKDPELVRAAADRFGSQCIVVNIDPKRVVVDGETKFEVFINGGRKPTGLQAVAWAQEVQRLGAGEIVLTSMDADGTCDGYDLEITAAVSNAVSIPVVASGGAGKPEHLADAIEIGRADAALAASIFHFGQFTIEETKRVMADRGIPVRLGSGVCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IS20</accession>
    <name>A0A518IS20_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Legionella pneumophila major outer membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_18750</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011446">
        <property type="entry name" value="BBP7"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07585">
        <property type="entry name" value="BBP7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021901034" evidence="1">
        <location>
            <begin position="28"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="322" mass="35491" checksum="55DC8C3C6384FC1B" modified="2019-10-16" version="1" precursor="true">MLKFRRKRFQVAAWFLLSMGITSIAQGQVECADPSLDDVVGGCETTRWSFGAKALFLERADDDNRIFWGPNGNFDSDELDLGFQAGYELNGRYNLNDSNALTVRWMSVDQWSDSHRDLVGPASNATLNAALPFTFPGVTSIDGIRTSDLHSLELGISRRFNDAIRFTAGFRYLEIDDRIGFRLDSFSTTTIDTAAQNRLYGGQIGLESELFRSGKWSLDGFGQVGLFGNAAKQSTLLDTGLVQLRDAGDRGKLSFLAELGLNARRSLTSQLDLVAGYQVMWITSVAVASDELVHSNILVPHGVDASDSLFYHGATVGLEYHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IS95</accession>
    <name>A0A518IS95_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_19440</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021811738" evidence="2">
        <location>
            <begin position="20"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="110"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="155" mass="16724" checksum="E323DAD569BB6999" modified="2019-10-16" version="1" precursor="true">MRLAAVALAFLTVSNFAAAAEDALRFSETEFATAQEGYLTLRWNEIAGAAEYQVIDDRDVTLYQGLFPEAFVSGLADGMHSFRVRALDANGDALAESEVPAQVEVKHWSVAFAMTLMTCGLVVFLAIISLIAVGTWRTRPAHASASEPHSEGSRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISC7</accession>
    <name>A0A518ISC7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="10">FG-GAP repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Mal33_19590</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.130">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002327">
        <property type="entry name" value="Cyt_c_1A/1B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013517">
        <property type="entry name" value="FG-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013427">
        <property type="entry name" value="Haem-bd_dom_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028994">
        <property type="entry name" value="Integrin_alpha_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013428">
        <property type="entry name" value="Membrane-bound_put_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011041">
        <property type="entry name" value="Quinoprot_gluc/sorb_DH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11961">
        <property type="entry name" value="PTHR11961"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00034">
        <property type="entry name" value="Cytochrom_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13517">
        <property type="entry name" value="FG-GAP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50952">
        <property type="entry name" value="SSF50952"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69318">
        <property type="entry name" value="SSF69318"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02603">
        <property type="entry name" value="CxxCH_TIGR02603"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02604">
        <property type="entry name" value="Piru_Ver_Nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 6" id="KW-0349">Heme</keyword>
    <keyword evidence="5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021845255" evidence="8">
        <location>
            <begin position="22"/>
            <end position="1566"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="9">
        <location>
            <begin position="1272"/>
            <end position="1404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="404"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="404"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV55980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1566" mass="172290" checksum="DC6CCCC31C977737" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISH8</accession>
    <name>A0A518ISH8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Translational regulator CsrA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">csrA</name>
        <name evidence="4" type="ORF">Mal33_20350</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CsrA/RsmA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048027">
        <property type="term" value="F:mRNA 5'-UTR binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044781">
        <property type="term" value="P:bacterial-type flagellum organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006402">
        <property type="term" value="P:mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045947">
        <property type="term" value="P:negative regulation of translational initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902208">
        <property type="term" value="P:regulation of bacterial-type flagellum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006109">
        <property type="term" value="P:regulation of carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00167">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003751">
        <property type="entry name" value="CsrA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036107">
        <property type="entry name" value="CsrA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34984">
        <property type="entry name" value="PTHR34984"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02599">
        <property type="entry name" value="CsrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117130">
        <property type="entry name" value="SSF117130"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1005">Bacterial flagellum biogenesis</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0810">Translation regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="49"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV56056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="154" mass="16505" checksum="8AF665B9B06E75E9" modified="2019-10-16" version="1">MLVLTRKAKQQIRLGDDIIVTVLQVKGNSIRLGIEAPRETRVVRGELEFYEEQPKSEGASGSRKQPEPAAVEAKPVAAKPTTAAGRSSVRGASKSNAAAVQVLGPTKLKIQQNSAVATRFPRTTERGQTVVSEVSPLKRFMPKSMVEAVGNVSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISZ2</accession>
    <name>A0A518ISZ2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_21950</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="92" mass="10485" checksum="474F48E337053883" modified="2019-10-16" version="1">MSNAQRLDEVRAFLQAWFSKSHPSNVWSATESILISDGHYCGRRFAFGPYTAIWFVEENQVKIFDPDGSVAVRQDCSELFGEEPTIEIRRAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IT21</accession>
    <name>A0A518IT21_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_22180</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
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        <source>
            <dbReference type="EMBL" id="QDV56236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="141" mass="16887" checksum="94BA84C433BA7FD8" modified="2019-10-16" version="1">MGWLFRQDITRKDLIAERTESWERQSGETIVQSECLAHCFRGCGFSGVLWAVWERRFVKDGEDTEQRQRWITCDLIQYRRNSGWGYKDMDESMGPYYYSCPMKYLELVPIDEYGGNASWRKEVIEHHQRQREKRNPPAIIV</sequence>
</entry>
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
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                <person name="Spormann A.M."/>
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                <person name="Jetten M.S.M."/>
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                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">Mal33</strain>
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    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <location>
            <begin position="163"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="290" mass="31957" checksum="1042C9BC1580CE87" modified="2019-10-16" version="1">MSKYPTRPRFFAHRFVRLLAKSGAANELGVNVCWMLTTIAMLEDSKRYRSHVTFYNEQLMGLCAFGGRKRLVEARDRAVAAGWLHYEQGGKSIPGKYWVLIPSHFEEIEDSGFDDSDVCRSETEQETVCRSDLIAQPEQQGDSNRNSKGTLSGAPSLPIPAPNPITVETSSTTKEKPRSQAKQSGRDCPMFQAFYAAYPRHIKPEAAAKAFASVAKKIAKKSGGDVTAAQKFLIDRAKAFAKSDSGQAGKFCPHPSTWLNAGDYDTDPAEWSATNGTPQRHETFDPSDAI</sequence>
</entry>
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                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
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                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
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                <person name="Mascher T."/>
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                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
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        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022146073" evidence="2">
        <location>
            <begin position="41"/>
            <end position="333"/>
        </location>
    </feature>
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        <location>
            <begin position="39"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="284"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="287"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="318"/>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="333" mass="35817" checksum="20285C384D45DC61" modified="2019-10-16" version="1" precursor="true">MLANLIQLRHGNQKSAVWVPRSLACLLLTLVSLGSATAQPADTSKPIADLPASEDPDRPQRPSTPEESESPTIKGVIAAFDAPKGATRLAPDARLWIDKPNRRVIVDGYVAVQEGLLEMFACPAGTKEHESAVAVLARSQYVHAALLAVGATPGRPVQFQPKFSPPTGDRIAIWVLWRDKEGKRHRAKAQEWICKTGTKEQLNTDFVFAGSQWWTDPRSGRDFYSADDGDLICVSNFASATLDVPIESSKDAEYLEFSACTENMPPRGTPIRMVMIPVSPALNAKPADKEKAGEAKPADKPAADAKLDADLDSLGPKDSPATQPTTPDAGSDS</sequence>
</entry>
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
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                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
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                <person name="Lage O.M."/>
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                <person name="Merkel B.J."/>
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                <person name="Devos D.P."/>
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                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="51"/>
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    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="51" mass="5089" checksum="63154B68756762EC" modified="2019-10-16" version="1">MTKNNEGAKPGTGKSGGSTNNTGGRVNAGYKGPTNVAKPTNLPPPPPKKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IU06</accession>
    <name>A0A518IU06_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
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    <gene>
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    <organism evidence="2 3">
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    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
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                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
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                <person name="Jeske O."/>
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                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
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                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
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                <person name="Mascher T."/>
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                <person name="Ovreas L."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
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        </location>
    </feature>
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    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
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    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="51"/>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="QDV56577.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="162" mass="16824" checksum="2D77B637A74A5FBF" modified="2019-10-16" version="1">MPKKSPRREDAASASTTSASESSTAAAPESSDAADAATATEDQTDAPLSDEDKPSDDEAEAGGDENLPSESDEVEATEPVDGGGSGSLLDDVQAFFDQREQLAQRLTDEIEATQAKLAELQETLAQLHPERGGSAGKERRPKKAKKPAVRNSGSAAEAKPDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
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    <name>A0A518IUC0_9BACT</name>
    <protein>
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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                <person name="Peeters S.H."/>
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                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
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                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
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                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
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            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011453">
        <property type="entry name" value="DUF1559"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07596">
        <property type="entry name" value="SBP_bac_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="334" mass="36085" checksum="9B918008FEA0A4D0" modified="2019-10-16" version="1">MRRRNGFTLVELLVVIAIIGILVGLLLPAVQAAREAARRMQCSNNMKQLGLALHNYVDTYQKFPASARGYGGCVGNAVNGEIKNANGLVALLPYIELQNVYDQFNHDEAFSVNPGGYQRATGTVVGDPITNGNAALAELELDVFLCPSDPNPAKGRLVGSAYGPGGSFSGAATNYDFIVKCGTEFGTCNSYATTSSTEKRMFGGDVNSRMAEVTDGLTNTFMVGETTKYHSNGAAFAWSYRAWVMTGIDPYYTTANGGINVWHQPWVAPTWQNPPYIPQRGRPRSWWVPAASLHPGGCHFVMGDASVQFINETIDKPTLLNLTVMSDGQVVTLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUC3</accession>
    <name>A0A518IUC3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA helicase</fullName>
            <ecNumber evidence="3">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">recQ_3</name>
        <name evidence="12" type="ORF">Mal33_26930</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the helicase family. RecQ subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004589">
        <property type="entry name" value="DNA_helicase_ATP-dep_RecQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006293">
        <property type="entry name" value="DNA_helicase_ATP-dep_RecQ_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029491">
        <property type="entry name" value="Helicase_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010997">
        <property type="entry name" value="HRDC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002121">
        <property type="entry name" value="HRDC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044876">
        <property type="entry name" value="HRDC_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032284">
        <property type="entry name" value="RecQ_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018982">
        <property type="entry name" value="RQC_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00570">
        <property type="entry name" value="HRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14493">
        <property type="entry name" value="HTH_40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16124">
        <property type="entry name" value="RecQ_Zn_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09382">
        <property type="entry name" value="RQC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00341">
        <property type="entry name" value="HRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00956">
        <property type="entry name" value="RQC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47819">
        <property type="entry name" value="SSF47819"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01389">
        <property type="entry name" value="recQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00614">
        <property type="entry name" value="recQ_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50967">
        <property type="entry name" value="HRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 12" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="10">
        <location>
            <begin position="36"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="11">
        <location>
            <begin position="225"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="domain" description="HRDC" evidence="9">
        <location>
            <begin position="531"/>
            <end position="611"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QDV56695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="733" mass="81030" checksum="2B5F3D805E2511EE" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUF4</accession>
    <name>A0A518IUF4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Neutral zinc metallopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Mal33_26880</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007343">
        <property type="entry name" value="Uncharacterised_pept_Zn_put"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30168">
        <property type="entry name" value="PTHR30168"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04228">
        <property type="entry name" value="Zn_peptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV56690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="293" mass="32628" checksum="BC58205C18E7839E" modified="2019-10-16" version="1">MRWRGRRESENIEDRRAMGAGPAVAGGGGLMILVVIVLGLMMGKDPQQLIQQVQQQQAQQQAGAPQNVPVEDSEAERELKQFVSVVLADTEDVWNKLFTEQIGKRYPEPKLVLFRDQVSSACGMASSATGPFYCPGDDQVYLDMSFFEQLQNQFGAKGDFAMAYVIAHEVAHHVQNTLGISDQVHRSQQSADKVAANRLSVRLELQADFLAGVWAHHGQKMKSFLDAGDVEEAMKCAEAIGDDRLQQQMQGRVVPDAFTHGTSKQRAYWFRKGLETGQIEVANELFELPYNQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUF7</accession>
    <name>A0A518IUF7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">mRNA interferase HigB</fullName>
            <ecNumber evidence="1">3.1.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">higB</name>
        <name evidence="1" type="ORF">Mal33_27170</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.-.-" evidence="1"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110001">
        <property type="term" value="C:toxin-antitoxin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018669">
        <property type="entry name" value="Toxin_HigB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09907">
        <property type="entry name" value="HigB_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="97" mass="11378" checksum="09E06E4FB758A664" modified="2019-10-16" version="1">MRIIARKTLVEFWTKYPRAEEQLKAWYAEADAASWTSPADVKAKYGNASILKDGRVVFNICGNEYRLVAWIKYEYYTVYIRFIGTHAEYDKIDAQKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUL4</accession>
    <name>A0A518IUL4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peptidase family M50</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_27800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="110"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="153"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="205"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="235"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="331" mass="36012" checksum="0E1DB9DF9E2797DB" modified="2019-10-16" version="1">MRSPSQIFDFTPSGLRLGRWRGTTYAIGWSYLGLGAVLFVAAWWLKVWPGNQDLPWLALVVWLAIGIVGGLQESAHAVTAWLLGGKSRLMMIAGHGGAGQYRIFGGPRQAIVAAAGPTSSCLFALLVAGILMFRGEASLWQMLDPLRPPELVGRLNLVSIGKVVAWIAITLSVVQMLPLWRCDGRTLLDGLVATFRPHYTPSARAHAATVAIGWIAFAMVGLSLAVAMFEDRQGVPRWPVLAAVGLVLWMSGQKVDPRIRVIDAKHQPIGWLGARRIRQAHHREIREASDIAKLDAILDRMTQHGADSLSHADRAVLKRASAALKKHSGKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUQ5</accession>
    <name>A0A518IUQ5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Biopolymer transport protein ExbB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">exbB_3</name>
        <name evidence="9" type="ORF">Mal33_28210</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the exbB/tolQ family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002898">
        <property type="entry name" value="MotA_ExbB_proton_chnl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01618">
        <property type="entry name" value="MotA_ExbB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="126"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="166"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="MotA_ExbB" evidence="8">
        <location>
            <begin position="105"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV56821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="218" mass="23868" checksum="D0B98E69E1FF8AB2" modified="2019-10-16" version="1">MSAMLLAKADVYTMIANSIYFALAAVALWGIYCVVIVWTRVAAKRFKSEDIQNDYLDDMAEPLEAGDFEAVLELVEGDARAIPQMVELAVENRELGYQKVKALVIERFQRDVIADLEHRLSWISTVIKSAPMIGLFGTVFGMMGAFKTLATAESVDPTMLAADINVALRTTACGLAIAVPLIIATASVNIRISKMEDLVGAGLNRFFEAFRSGLSRPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUZ9</accession>
    <name>A0A518IUZ9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_29190</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="403" mass="45220" checksum="AA8B070AD42146CC" modified="2019-10-16" version="1">MTHTFASPTSLSAWLFAIASLTCDPSRALSAEDLVEPVEQRLDLQIDRLGASSYRMRERTSRAFVAAGDAAIEPLRLGLDNDDAEIRLQCQRLLIEIRERRTAWELQHLLTQYDPERSYRLAGWQPFVEACGDDASARGLFKRLLDRDAAFMAWLQRVYDDPGYDIENQLEDQQRYLSPDTQRLNSGDLVSWSMLLLAGTNAKICQVPVLGSHIRCGLQCSPAIHSLTRGNNRVATMRLVRSWLQRQASTAATRSTLRIAMLYQCDQIAEQLASATLSSDHASPASVQTALFFLVAHDPQTARPRLVDALQDHRVCQVWQIASRRRRAIQTQVRDTALALLLHLQGIDPRTVGFRDLQADPVTIYSEQTLGFETEQARAEAHDAGQRLIAEFDPNAIAHSSSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVB0</accession>
    <name>A0A518IVB0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GDSL-like Lipase/Acylhydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_30190</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="492" mass="54869" checksum="AFA8DD0921C86502" modified="2019-10-16" version="1">MYPINKASKHIARAGSWRVCRARGIAFRLIALAIGLLPLLMIESTLWVLDFPRAESRIEAIGEANGTRRLFVLNRATGRYEIAPDRLNLFRPDSFVAEKPADLRRVFVLGGSTVQGRPYQIETAFSTWLGLALQSCDPRHRWEVVNCGGVSYASYRVAAILDEVLDYQPDAIILYIGHNEFLERQSFGQLQRLPDWLVPSLSAVERMRTFQLLRSQIFADAALEPSTRELLTHNVEALLDNQGGLAEYHPDAPPRGAVEEAFAENLDAMIAYCRQRNVPVIVCCPARNLVDCPPFKSEPLVPLDDSDQRAFDAAMATATDEQAAAADRIAALRAAQALDPQNPSVAFRLGRLMLQAGEIETARQQLTLAADNDSCPLRIRSSMQSHIRAIAAQRQVPLLDVDRLMQSHSRNGLVGAKWMVDHVHPTVHGHQIIADALLEILVDQRLTTSDVDCQSNREAAYADHLRSLDESYFVRGQQRLEGLKQWAAGRAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVL4</accession>
    <name>A0A518IVL4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Chemotaxis protein CheY</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">cheY_3</name>
        <name evidence="3" type="ORF">Mal33_31300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="9"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="167" mass="18408" checksum="2C9540D5D28A37F9" modified="2019-10-16" version="1">MPNSEQPKRCVIADDVRASREILKSWLSDCNFECSLATDGNEAWEMIQRAPTDMLITDIEMPNCCGLELLQRIRADPSPQIQSIPVLMITSLHDGQIQQTIRRLGGNGLLAKPLDQYSTYSIVLAVLAAGDDRDSLLVSDPNGKINGDGLVSPTFRRLLKPLFASEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVT7</accession>
    <name>A0A518IVT7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_31960</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021945984" evidence="1">
        <location>
            <begin position="24"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="330" mass="36527" checksum="10D27DB929CB0C2F" modified="2019-10-16" version="1" precursor="true">MRTKFSIWLILLVAIMNQSTNHADEPVPESAGFVANLKLPTLGGVQFWTDLRWWYGWRIQQNKLTDQCRLLNPSNIRHFSGSREACDARLAEIVSDGPWPEPPQRVVICLHGLMRTHRSFASLGKRIEKETPATVIHFGYASTRAPVSQHARALRGLIESLPGQPQIDLVGHSMGNIVARHAIGDWQTEGDPAGVLDRLGRFVMQGPPNQGAQIAKRLQSTTVFEIITGTSGVQLGINWDELQQHLATPPCEFGIIAGAFEMGRFRNPLVDGDSDLIVSVEEAKLSGANDFVIVPVLHSFLMDDKDVQELTLRFLETGAFADDGQRNPLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVZ8</accession>
    <name>A0A518IVZ8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Hydroxypyruvate isomerase</fullName>
            <ecNumber evidence="4">5.3.1.22</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">hyi_2</name>
        <name evidence="4" type="ORF">Mal33_32640</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the hyi family.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.22" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008903">
        <property type="term" value="F:hydroxypyruvate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026040">
        <property type="entry name" value="HyI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013022">
        <property type="entry name" value="Xyl_isomerase-like_TIM-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01261">
        <property type="entry name" value="AP_endonuc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006241">
        <property type="entry name" value="HyI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="SSF51658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AP_endonuc_2" evidence="3">
        <location>
            <begin position="27"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="2">
        <location>
            <position position="140"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="2">
        <location>
            <position position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR006241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR006241-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV57260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="256" mass="28158" checksum="C45DCD4E5ADF9DBB" modified="2019-10-16" version="1">MKFESGLHPSVCIDAVFESLPAPQAIQQVADCGLKAFEFWGWWDRDLDAIAAARDQHDMTISACCTRFISLVDPTLRDDYLAGLEASIAAAQRLQCKTLISQVGDLIPGVDREDQFRSLVDGLTQAAPMLEAAGITLVIEPLNELVDHPGYYLIRSDEAFAAVDQVGSDRVKVVFDIYHQQISEGNVIANIAKNIDKIGHFHAAGNPGRHELTRGELHYPSIFAAIADAGFDGFVGLEYWPQDDPATGLRQITDWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IW17</accession>
    <name>A0A518IW17_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">50S ribosomal protein L5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 9" type="primary">rplE</name>
        <name evidence="9" type="ORF">Mal33_32790</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uL5 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01333_B">
        <property type="entry name" value="Ribosomal_L5_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002132">
        <property type="entry name" value="Ribosomal_L5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020930">
        <property type="entry name" value="Ribosomal_L5_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031309">
        <property type="entry name" value="Ribosomal_L5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020929">
        <property type="entry name" value="Ribosomal_L5_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022803">
        <property type="entry name" value="Ribosomal_L5_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031310">
        <property type="entry name" value="Ribosomal_L5_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11994">
        <property type="entry name" value="PTHR11994"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00281">
        <property type="entry name" value="Ribosomal_L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00673">
        <property type="entry name" value="Ribosomal_L5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002161">
        <property type="entry name" value="Ribosomal_L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55282">
        <property type="entry name" value="SSF55282"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00358">
        <property type="entry name" value="RIBOSOMAL_L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="5" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L5" evidence="7">
        <location>
            <begin position="28"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal_L5_C" evidence="8">
        <location>
            <begin position="89"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV57275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="195" mass="21837" checksum="FAFE6065FEDE7D34" modified="2019-10-16" version="1">MADYVPRLQTMYQNEIRSALQEKHGLKNPMTVPRLEKITLNMGVGSATQDKKNLETAYAAMTEIAGQKPIFTKARKSIANFRLREGMAIGCMVTMRGARMYEFLDRLVSVVLPRVRDFRGISRKAFDGRGNYSMGLSEIMVFPELNPDKFTKPQGLNITIATTATNNDHGRDLLEMFGMPFREDPKKAAEAAAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWD9</accession>
    <name>A0A518IWD9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DoxX</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_34030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="246"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="284"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="325" mass="36423" checksum="E4D9A7112AD80EDC" modified="2019-10-16" version="1">MVSEKIPSAAPSRLATLCIPLRLATGWGPYPKKLSLLAALMLILLRLSIGWQFYSEGTDKIQNGFDSSRFLSAARGPFAEHFHAVVWDRDGGLRLDDEATERRWQWYRNTAGSHFGFDDAQQKQADQVLKRTLNQYQFVLDNNVDELAEIDFGRQRLADLAARPERNDVTSLIGQKETIEREWRQKLDPILSEVDNAWENLERDMNAVASDDQLRRHGHLELPPLRNQRIDTTVMDKFVPWFDCTIGVLLILGLFTPVAALAAAGFLFSVFLSQFPPATGPTSTYYQLIESMACLVIASTGAGRFAGLDSIIHAAFNRGGSHEQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWH5</accession>
    <name>A0A518IWH5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NADP oxidoreductase coenzyme F420-dependent</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_34580</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028939">
        <property type="entry name" value="P5C_Rdtase_cat_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03807">
        <property type="entry name" value="F420_oxidored"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F420_oxidored" evidence="1">
        <location>
            <begin position="3"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="210" mass="22557" checksum="9C64D4A9B34BE0A6" modified="2019-10-16" version="1">MDIAVLGTGNVGATLGRRLAGLGHNIVFGSRLPQSERVQQLIEENPHAHAAETIAEAARQCDTILFAAPWTAARETLTNAGDLTGKTLIDCTNPLNETFDGITLGHTESAAEKIAHWAVGAHVVKAFNTASLATMENPDFDGQRATMFYCGDDVTAKATAGTLIDELGFEAIDAGDLQSARYLEPMAMLYIQLAIHQKMGSQFALKMLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWI5</accession>
    <name>A0A518IWI5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RNA polymerase sigma factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rpoS_2</name>
        <name evidence="8" type="ORF">Mal33_34250</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the sigma-70 factor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000943">
        <property type="entry name" value="RNA_pol_sigma70"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009042">
        <property type="entry name" value="RNA_pol_sigma70_r1_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007624">
        <property type="entry name" value="RNA_pol_sigma70_r3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007630">
        <property type="entry name" value="RNA_pol_sigma70_r4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00140">
        <property type="entry name" value="Sigma70_r1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04539">
        <property type="entry name" value="Sigma70_r3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04545">
        <property type="entry name" value="Sigma70_r4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000770">
        <property type="entry name" value="RNA_pol_sigma-SigE/K"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00046">
        <property type="entry name" value="SIGMA70FCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00715">
        <property type="entry name" value="SIGMA70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00716">
        <property type="entry name" value="SIGMA70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="4 5" id="KW-0804">Transcription</keyword>
    <keyword evidence="1 5" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="RNA_pol_sigma70" evidence="6">
        <location>
            <begin position="95"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_sigma70" evidence="7">
        <location>
            <begin position="264"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV57415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="304" mass="33869" checksum="6FB89D1B5B07EC96" modified="2019-10-16" version="1">MVEELVAVDPGLEDIKAARSRTTVRAKDPAVQSPLETYLREINETALLSAEEEQQLAGGIAQGDVMARDRMVRANLRLVVNIARGYTGKGLGLQDLIEEGNLGLLRAVEGFDPNVGTRFSTYASYWIKQSIKRALINSAKTIRIPAYMVELLSKWRRATARLTEELGRTPTNEEVARVLGLPKKKLPIIKKAIRINNSTPQSDQSESGWSLGEMVMDEKQKSPDDAMQDDDIMHHALQMLGRLESREATVIKMRFGLDGSEPHTLKEIGAELGLTRERVRQIETEALNRMADALKDPKERIGLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWL2</accession>
    <name>A0A518IWL2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_34830</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2310.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035093">
        <property type="entry name" value="RelE/ParE_toxin_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="104" mass="11516" checksum="A67DEF202F045472" modified="2019-10-16" version="1">MDVHLRPEAVDDIYRAAQFFNNKSDGWGDHFVARIQEDLVALRTTAGSHGTRFGVSCAFSRKFPFAIYYRTEGGTAVVYAILSCRQSTGVQRSIIRGRSGPGND</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWU4</accession>
    <name>A0A518IWU4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative efflux pump membrane fusion protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_35670</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039562">
        <property type="entry name" value="MFP_biotin_lipoyl_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13533">
        <property type="entry name" value="Biotin_lipoyl_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Biotin_lipoyl_2" evidence="3">
        <location>
            <begin position="84"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="113"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="184"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV57557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="455" mass="48648" checksum="06E2D3AD9CC78CE6" modified="2019-10-16" version="1">MTSARTRSMTILVAVPVAGLAIFFAANNWTGASQGPPDAAAIIASSAGSRPLPVTTLQLGQLAAPPRIDDYRGTIQASKEADLAFRRSGRVLSIAVEEGDIVRRGQTLAQLEVDDLDAIVEATEARIAEAEAMLAELEAGPRKQTIAAAAAEVSRLSAAVELAQITTARELELQRSNSSSIQSYDNARFQAAQQESALEAADQQLKELQAGTRPEQLAAQRARVAMLHAELKGYQVDLRDGRIVAPFDGVVGRRFLDEGTIASPDRIVLRVIQTDPLEARFGVSPEDARTLSPGQEVAVTVGPTTIQAIIGRIEPELDRSTRTQAVLVTIPREQQRPDGSYADGIVPGRTASLSLGVARTSDSDSYWVPITSLARSTRGLWSLMLVVEDSPGHFAVQRRDVQVLETDTRLARICGGMIAAGDHVVAAGLHRLTPGMAVAPVDRKPPHIVETFSLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IX06</accession>
    <name>A0A518IX06_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Serine-aspartate repeat-containing protein D</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">sdrD_2</name>
        <name evidence="4" type="ORF">Mal33_36350</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041033">
        <property type="entry name" value="Prealbumin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033764">
        <property type="entry name" value="Sdr_B"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17210">
        <property type="entry name" value="SdrD_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17802">
        <property type="entry name" value="SpaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="SpaA" evidence="3">
        <location>
            <begin position="483"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="domain" description="SdrD_B" evidence="2">
        <location>
            <begin position="573"/>
            <end position="642"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV57622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="879" mass="91692" checksum="5F8F5D17511A47D8" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IX60</accession>
    <name>A0A518IX60_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Calx-beta domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_36840</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
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                <person name="Galperin M.Y."/>
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            <strain evidence="5 6">Mal33</strain>
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</entry>
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                <person name="Rast P."/>
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</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
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        <submittedName>
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    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
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                <person name="Peeters S.H."/>
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                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <dbReference type="EMBL" id="QDV57703.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
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    </evidence>
    <sequence length="117" mass="12784" checksum="FAD67A60FB61A803" modified="2019-10-16" version="1">MNRHEKINYVEFPARDLAATKAFFTAAFGWTFVDYGPQYTAFSDQGLDGGFYQAELAANAELGSALIVLYSDSLEATQAKVEQAGGAVVKPIFSFPGGRRFQFTEPSGNELAVWSDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
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    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
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                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
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                <person name="Devos D.P."/>
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                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </dbReference>
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        <property type="entry name" value="PYRIDINE_REDOX_2"/>
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    <proteinExistence type="predicted"/>
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    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="3">
        <location>
            <begin position="7"/>
            <end position="336"/>
        </location>
    </feature>
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        <source>
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    </evidence>
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    </evidence>
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    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="354" mass="37978" checksum="8A6B4A86B2C9A8BA" modified="2019-10-16" version="1">MSDTIEKTVIIGSGPAGWSAAIYAARANLNPVVYEGTVRPEMIPLGQLAFTTEVENFAGFPAGNIRAFVESAVDKSRHWNLPPAPEGHEKDGQPHYAVQGVELMELMKQQALNFGTRVVSDDIASVDFSGDVHTLTAGNGDTVKAHTVIIATGARANYIGLESEDAYKNKGVSACAVCDGALPLYRSKPLAVVGGGDSAVEEATYLANLKGADKIYLIVRRDEMRASKVMQERALNHPNIEMCWNTVVDEVLGDGKLVNALRLRSTVDDSTRELKVGGMFVAIGHTPNTAFLGGAVTMNDKGYIQWTKPFRTNTNVEGVFAAGDVADDYYRQAITSAGTGCMAALDAERYLAEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXH1</accession>
    <name>A0A518IXH1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RNA polymerase sigma factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_38070</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014331">
        <property type="entry name" value="RNA_pol_sigma70_ECF_RHOBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02989">
        <property type="entry name" value="Sig-70_gvs1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="2">
        <location>
            <begin position="18"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="3">
        <location>
            <begin position="113"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV57792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="178" mass="20957" checksum="FA23D2E23EA13C9E" modified="2019-10-16" version="1">MDDKPSDPDDYELFLRLFARDQLRVLAYIRSLIYQPCAVDDVYQETCLELWRSFSTFRRDQDFTAWALGVTRHQVLKHWRTRDRDRHVFSEALVDELSATALKLGPEINVRQEAIDQCVQLLSERQRELVQLFYGENHSAAAIAQRWQRSVHAVYKSLKVMRRSLADCVESKLQNEPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXM2</accession>
    <name>A0A518IXM2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">EamA-like transporter family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_38420</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="17"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="125"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="155"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="181"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="221"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="249"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="288"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="329"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="357"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="218"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="383" mass="41731" checksum="3F491D608D4F459E" modified="2019-10-16" version="1">MRNLSVLQASRLGNNSAIVKIGTFAIPCLPASWVPTMLAPVQPSDRRRAIVALVLVNSMWGLSFPMMKCLNMQVDEHFSVTHLTASPMLRSSAAAWMIGIRFTAAMLLYLLFFHRTLRQVQMPHLLAGAAIGAMFVMGLILQVIGLGTIPASRSGFLTSLVVVVTPIISAIAQRRMPRPTVIAGAMLALFGVAVLAEVIQLRDGRIGFAADMRQTWTTGDWLTLLSVFFFSGQILLLDQLGKRYHSIAFTPSMFATTALLAFCTFAWLQFHVPESAVGGWTSLAVKPSFYLMLILLCSIPSLIAFAWMNKYQPMISAGQAAVIYTLEPVFASLWAMTLPAALSLCCTVAYANETFSTPLVIGGALVLTANALVLWPQRRADSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXQ3</accession>
    <name>A0A518IXQ3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">3-isopropylmalate dehydrogenase</fullName>
            <ecNumber evidence="13">1.1.1.85</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">3-IPM-DH</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Beta-IPM dehydrogenase</fullName>
            <shortName evidence="13">IMDH</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13 16" type="primary">leuB</name>
        <name evidence="16" type="ORF">Mal33_38710</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13 14">Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13 14">
            <text>(2R,3S)-3-isopropylmalate + NAD(+) = 4-methyl-2-oxopentanoate + CO2 + NADH</text>
            <dbReference type="Rhea" id="RHEA:32271"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:17865"/>
            <dbReference type="ChEBI" id="CHEBI:35121"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.85"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13 14">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="13 14">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="13 14">Binds 1 Mg(2+) or Mn(2+) ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 13 14">Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 3/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 13 14">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.85" evidence="13"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00048">
        <property type="reaction ID" value="UER00072"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003862">
        <property type="term" value="F:3-isopropylmalate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01033">
        <property type="entry name" value="LeuB_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019818">
        <property type="entry name" value="IsoCit/isopropylmalate_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024084">
        <property type="entry name" value="IsoPropMal-DH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004429">
        <property type="entry name" value="Isopropylmalate_DH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42979">
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="12 13 14" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 13 14" id="KW-0432">Leucine biosynthesis</keyword>
    <keyword evidence="9 13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="13" id="KW-0464">Manganese</keyword>
    <keyword evidence="8 13 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 13 14" id="KW-0520">NAD</keyword>
    <keyword evidence="10 13 16" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="4"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="76"/>
            <end position="89"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
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        <location>
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        </location>
        <ligand>
            <name>substrate</name>
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        </location>
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    <feature type="binding site" evidence="13">
        <location>
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        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
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    <feature type="binding site" evidence="13">
        <location>
            <position position="251"/>
        </location>
        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
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    <feature type="binding site" evidence="13">
        <location>
            <begin position="281"/>
            <end position="293"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalysis" evidence="13">
        <location>
            <position position="141"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalysis" evidence="13">
        <location>
            <position position="190"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00000624"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
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        <source>
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        <source>
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    </evidence>
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        <source>
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        </source>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU004445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM01329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="QDV57856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="356" mass="37886" checksum="A8CBFC2C537D9F0A" modified="2019-10-16" version="1">MKANIVLLPGDGIGPEIVLQGQRVLDAIATKFNHQFTYQSCLIGGIAIDQTGDPLPQPTIDACLASDAVLLGAVGGPKWDDPSAKTRPEVGLLKIRKELGLFANLRPIQTFPELVGASPLRREIVEGTDILFFRELTGGIYFGPSGRETIDGVEHAMATMVYSVPEVERVVRLAAEAARGRDGRLTSVDKANVLEPSRLWRQVAERVVREEFPDVKYDVVLVDAMAMHLISRPKDFDVVVTSNMFGDILTDEASMLPGSLGMLPSASIGADGPGLYEPIHGSAPDIAGKGIANPLATILACAMLLRHSLKLEDEAAAIEAAVRKVLAAGHRTPDIAAGEASIGTEAMGDEVLKVLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXQ6</accession>
    <name>A0A518IXQ6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_38830</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="347" mass="38514" checksum="8C1EF52AB7F92BD6" modified="2019-10-16" version="1">MRFVNIPRSSNVVDAVHSMSSRSIATLGVVLLLTVLSSSVSHAALLREGDEYWVLNSRCISSVACRANLENPNLKVYRYHQGQGLQHDSVNGLYTRVDEDHSFLNVIYVHGNRFTSQEAIDRSLKIYRSVNRRCHDQTRIRWILWSWPSDPIFNPLTDVRTKAQRADTQALYVGWLLQHFPAPDRLEMIGYSFGGRIVTGALHTAAGGEMKGRTLSGPPLRGSRIGIHLVAPALDRHWLASGSRHGLAAENIGSMNLFYNSRDRVLKLYSMVSKYYNPVALGFAGLGQLAARSDHLPIQIRARDCGGAVGLLHDELKYFEPCCNVAETIATTLDASDSEVIQLTAAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXR7</accession>
    <name>A0A518IXR7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Anaphase-promoting complex, cyclosome, subunit 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_38930</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="255" mass="27861" checksum="40E4FD42A30567A1" modified="2019-10-16" version="1">MLHSTEISVAEYQAGNYHRAIQFARYALARDDENAAAWRCLARALVQTYSIVAAIDAFENAALLQPLEPQDSISLAIAYGAAGRRGLSRDLLMTVANSDSIDVEGLLQVATGLEALDEPRLAMEACRRAGKLAPDSAQVHYQMGYYAQLAGQPVSIGEALVRHAINLEPRNLHYRIGLASMLIRLGRKCEAIAVIDHLIPKQLHEVSCLCCLKRIANLFFDGDDLHRARLCAQRIAELTAAASEKGHSPDATVMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXY0</accession>
    <name>A0A518IXY0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ATP synthase epsilon chain</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">ATP synthase F1 sector epsilon subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">F-ATPase epsilon subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 9" type="primary">atpC</name>
        <name evidence="9" type="ORF">Mal33_39590</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Produces ATP from ADP in the presence of a proton gradient across the membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6 7">F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the ATPase epsilon chain family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045261">
        <property type="term" value="C:proton-transporting ATP synthase complex, catalytic core F(1)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12152">
        <property type="entry name" value="F1-ATPase_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00530">
        <property type="entry name" value="ATP_synth_epsil_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001469">
        <property type="entry name" value="ATP_synth_F1_dsu/esu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020546">
        <property type="entry name" value="ATP_synth_F1_dsu/esu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036771">
        <property type="entry name" value="ATPsynth_dsu/esu_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13822">
        <property type="entry name" value="PTHR13822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02823">
        <property type="entry name" value="ATP-synt_DE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51344">
        <property type="entry name" value="SSF51344"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01216">
        <property type="entry name" value="ATP_synt_epsi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6 7" id="KW-0139">CF(1)</keyword>
    <keyword evidence="6" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="3 6 7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6 7" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ATP-synt_DE_N" evidence="8">
        <location>
            <begin position="4"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV57943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="130" mass="14064" checksum="41905E7715B0C2C0" modified="2019-10-16" version="1">MAKLKCVVVTPEKTEIDREVDSLVLPLYDGAMGVLPGRAPLIGRLGFGQLELTDGSSTETYFVDGGFAQVENNVVSILTGRAMPVSDIVYADAEKELAAALQLPANTEEQRQVRDASALRARGQMRISRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IY33</accession>
    <name>A0A518IY33_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HDOD domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_40110</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013976">
        <property type="entry name" value="HDOD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08668">
        <property type="entry name" value="HDOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51833">
        <property type="entry name" value="HDOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HDOD" evidence="1">
        <location>
            <begin position="19"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="295" mass="32363" checksum="F2FD399CEA78B621" modified="2019-10-16" version="1">MTTATATTKLSEVLTAAQLPALPQSAITLLQLSQDPNNGPAEFARPIEADPGLLGQVLKFVNSAYFGFSREIASVQQALTLVGVRAITNFALWSAVFSLVPNPKFGAFDLKGLWQDSLRRGLFARLLGRQLKLREAEDLFAGALLQDMAIPLLLKELPEQYAPLLERRISENARLSSLEKEFFGWDHAEAAGVLARKWNLPEEFAGLMENHTQLDQLLAGGESLRGRACVALASLLPSCNDPNWNEKDLFVAGYRQLVGSTNDLKSLLQDVDESAEKFAPLLKLPVPQIRLADIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYH6</accession>
    <name>A0A518IYH6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">YcfA-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_41560</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HicA mRNA interferase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.920.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012933">
        <property type="entry name" value="HicA_mRNA_interferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038570">
        <property type="entry name" value="HicA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07927">
        <property type="entry name" value="HicA_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-1277">Toxin-antitoxin system</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006620"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV58139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="62" mass="6786" checksum="60EF447AA9B2C4D7" modified="2019-10-16" version="1">MTVREVVHIIEGDGWVMVAQKGSHRQFKHPTKTGRVTVAGHPKDDIAPGTLNSILRQAGLKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYI0</accession>
    <name>A0A518IYI0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Cyclic nucleotide-gated potassium channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Mal33_41660</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008076">
        <property type="term" value="C:voltage-gated potassium channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005249">
        <property type="term" value="F:voltage-gated potassium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028325">
        <property type="entry name" value="VG_K_chnl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027359">
        <property type="entry name" value="Volt_channel_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11537">
        <property type="entry name" value="PTHR11537"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10 13" id="KW-0407">Ion channel</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0630">Potassium</keyword>
    <keyword evidence="5" id="KW-0631">Potassium channel</keyword>
    <keyword evidence="3" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="46"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="76"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="140"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="170"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="201"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="domain" description="Ion_trans" evidence="12">
        <location>
            <begin position="17"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="QDV58149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="234" mass="26432" checksum="CB11C23226F332C7" modified="2019-10-16" version="1">MPTLKDIVERSDTPIGRVFDLSIQFFIILSLIAFSVETLPGLDPGWARLLHFFEIASITVFSVEYLVRLLVADRKIAFMTSFFGVVDLLAILPFYLSFGVDLRSIRALRLLRLFWMLKLVRYSRAIQRFHRAFLISREEIILFFFVTVILLYLASVGIYHFEHAAQPEAFASVFHCLWWAVVTLTTVGYGDVYPITAGGRIFTFAILLIGLGVVSVPAGLVASALAQAREMESE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYQ5</accession>
    <name>A0A518IYQ5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">Ribonuclease H</fullName>
            <shortName evidence="5">RNase H</shortName>
            <ecNumber evidence="4 5">3.1.26.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rnhA_2</name>
        <name evidence="5" type="synonym">rnhA</name>
        <name evidence="7" type="ORF">Mal33_42360</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>Endonucleolytic cleavage to 5'-phosphomonoester.</text>
            <dbReference type="EC" id="3.1.26.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="5">Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 5">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the RNase H family.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.4" evidence="4 5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004523">
        <property type="term" value="F:RNA-DNA hybrid ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006401">
        <property type="term" value="P:RNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09278">
        <property type="entry name" value="RNase_HI_prokaryote_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00042">
        <property type="entry name" value="RNase_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002156">
        <property type="entry name" value="RNaseH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022892">
        <property type="entry name" value="RNaseHI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00075">
        <property type="entry name" value="RNase_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50879">
        <property type="entry name" value="RNASE_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase H type-1" evidence="6">
        <location>
            <begin position="11"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="20"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="149"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV58219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="160" mass="17871" checksum="2F5EB310B178BE14" modified="2019-10-16" version="1">MDAATSTPSQPTRMIHLFTDGACSGNPGPGGWAYVLRDLQSGTEKECSGGLVETTNNQMEMLAVIRGLEALKRPCKVTLYSDSSYVGQGLSKWMAGWKRNGWRRKVGTKFAELKNAELWKELDRQLQIHAVTFEHVKGHSGHEENERCDQLAVAAYQRFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYT0</accession>
    <name>A0A518IYT0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glucokinase</fullName>
            <ecNumber evidence="1">2.7.1.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">glcK_2</name>
        <name evidence="1" type="ORF">Mal33_42590</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.1.2" evidence="1"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004340">
        <property type="term" value="F:glucokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000600">
        <property type="entry name" value="ROK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18964">
        <property type="entry name" value="PTHR18964"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00480">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01125">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="347" mass="36413" checksum="D43B8D5DF9A10642" modified="2019-10-16" version="1">MPSSAPATTLDDATKPLFWGIDIGGTNIKIGLVDDAGKTLHFDHIPTQESEGPQSAVDRTAAFLAKIEQELGLSHEDVPVIGLGSPGSMDIPRGYLLDPPNLPHWWNFPIRDAFAEATGRPVAFINDANAAAYGEFWVGTGQRQDNMVLLTLGTGVGGGIVVADELVDGENSFGGECGHMIVDPSPTARLCVWGGGRGQLEAYASASAVVDRTRERLTAGGESSLSGLLGGSNTELSAKAVYLAAEEGDALALEIVDETAFWLGIGITTIIHMIDPGLVVLGGAMDFGGEASQVGQRFLEGIRKEFHARTFAHVAKGTKIGFASLGGDAGYLGAAGYARKAYRKRMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ25</accession>
    <name>A0A518IZ25_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_43640</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="126"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="155"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="181"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="208"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="300"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="336"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="364"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="390"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="432"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="464"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="504"/>
            <end position="525"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="535" mass="56981" checksum="A3857E7E65FBC595" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ36</accession>
    <name>A0A518IZ36_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Creatinine amidohydrolase</fullName>
            <ecNumber evidence="5">3.5.2.10</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">crnA_2</name>
        <name evidence="5" type="ORF">Mal33_43660</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the creatininase superfamily.</text>
    </comment>
    <dbReference type="EC" id="3.5.2.10" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047789">
        <property type="term" value="F:creatininase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024087">
        <property type="entry name" value="Creatininase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003785">
        <property type="entry name" value="Creatininase/forma_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35005">
        <property type="entry name" value="PTHR35005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02633">
        <property type="entry name" value="Creatininase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102215">
        <property type="entry name" value="SSF102215"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV58348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="259" mass="28783" checksum="5F5AE349B2FB334F" modified="2019-10-16" version="1">MKSILEEMTLADVRDADFRVAVLPFGATEPHNLHLPYGTDTLEGRCIGQAICDAANAQGGRVVLLPTIPYGTETNMNQLPLAMNLNPSTVLMVVKDLVESIQRAGIRKIVFLNSHGGNELKPVLRELHGQTNSQLFLCNWFQMVRDRYHEIFEVAEDHAGEMETSLALAYFPEFVVHNDDDTLRADAGSRRPMRFEALNEGWVSITRPWHLLTTNSGSGNPHAASADKGRAVMDLIVQRIAPFLAELSQAELDDEFPFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ62</accession>
    <name>A0A518IZ62_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fatty acid desaturase</fullName>
            <ecNumber evidence="3">1.14.19.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">des</name>
        <name evidence="3" type="ORF">Mal33_43950</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.14.19.-" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012171">
        <property type="entry name" value="Fatty_acid_desaturase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19353">
        <property type="entry name" value="PTHR19353"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="160"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="187"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="212"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="FA_desaturase" evidence="2">
        <location>
            <begin position="58"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="335" mass="37528" checksum="82E3432AD67B0667" modified="2019-10-16" version="1">MTFDKPTDQRGEPRSPKQLLIASKEFASEHRLLSWWHLWSTLAVCFALIGVSVSDLSLWLRIPASIAVGLVTVRLFIIYHDFQHSAILAKSVLARWIMATYGMLVLAPTSVWKHSHDVHHRKNSQTFGANVGSYPIMTTHAYANAMASEKFSYAASRHPLTIVLGYFTVFIWRMCLQAFISNPREHFDGGVSILLHIALAIGLLMFGVDIMMLGLIVPLFVASGLGAYLFYAQHNYPSAKMHPSSEWSHVDAALQSSSFIPMNPLMNWFTGNIGYHHVHHLNARIPFYRLPEAMAALPELQTPGVTTLRPGDIAACLRLKLWCPDQEKFVGFNGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZD4</accession>
    <name>A0A518IZD4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aminodeoxychorismate synthase component 2</fullName>
            <ecNumber evidence="2">2.6.1.85</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">pabA_2</name>
        <name evidence="2" type="ORF">Mal33_44770</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.6.1.85" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046820">
        <property type="term" value="F:4-amino-4-deoxychorismate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071704">
        <property type="term" value="P:organic substance metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd01743">
        <property type="entry name" value="GATase1_Anthranilate_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006221">
        <property type="entry name" value="TrpG/PapA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00566">
        <property type="entry name" value="trpG_papA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GATase" evidence="1">
        <location>
            <begin position="25"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="225" mass="25016" checksum="E2769E749C7330EB" modified="2019-10-16" version="1">MCQRRRGISWLERMQNVRIAAMLLVLDNYDSFVHNLARYVRRQGHHTLVVRSDKISVDEVEALSPAAIILSPGPKAPDQAGACLEITRRFAGRLPILGVCLGHQIIAQAFGGRIVRSEPMHGVPSSIEHRGDGLFRGLPNPFPAARYHSLVADAAQIPDVLEVTAWTEREPGDPGDRLVMGLQHREFPIFGVQFHPESILTEHGDEMLKNFLDRLPAVEATVANR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZK0</accession>
    <name>A0A518IZK0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Holliday junction DNA helicase RuvB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_45390</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011703">
        <property type="entry name" value="ATPase_AAA-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041628">
        <property type="entry name" value="ChlI/MoxR_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07726">
        <property type="entry name" value="AAA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17863">
        <property type="entry name" value="AAA_lid_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_3" evidence="1">
        <location>
            <begin position="48"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="AAA_lid_2" evidence="2">
        <location>
            <begin position="257"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="336" mass="37569" checksum="6B73E58256495481" modified="2019-10-16" version="1">MSETFSDPERAEQLVQACEKIRAQVGRVVVGQETVVEQILIAILARGHCLLEGVPGLAKTLMVKSLADAMHLAFHRIQFTPDLMPADITGTDIIQESDAGHRELVFDKGPIFTQMLLADEINRTPPKTQAALLEAMQEHEVTVGGTTYKLQEPFFVLATQNPIEQEGTYPLPEAQRDRFLFLVNVEYPTRDQEAMIIDRTTGSFDSKVEPVVTGDEIIAFQKTVRMVPLPEHVRNFVLDIVRSVRPREESCLPWVRQLVEWGPGPRACQQLVLASKARALLHGRYHVTIDDIEALALPVLRHRIVPTFNAEAEGISVADLVKRLLADVPRPKAQLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZU4</accession>
    <name>A0A518IZU4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Mannitol 2-dehydrogenase</fullName>
            <ecNumber evidence="3">1.1.1.67</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">mtlK</name>
        <name evidence="3" type="ORF">Mal33_46400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.1.67" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050086">
        <property type="term" value="F:mannitol 2-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019594">
        <property type="term" value="P:mannitol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000669">
        <property type="entry name" value="Mannitol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013118">
        <property type="entry name" value="Mannitol_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023027">
        <property type="entry name" value="Mannitol_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013131">
        <property type="entry name" value="Mannitol_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01232">
        <property type="entry name" value="Mannitol_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08125">
        <property type="entry name" value="Mannitol_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00084">
        <property type="entry name" value="MTLDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00974">
        <property type="entry name" value="MANNITOL_DHGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mannitol_dh" evidence="1">
        <location>
            <begin position="32"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="Mannitol_dh_C" evidence="2">
        <location>
            <begin position="224"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="500" mass="55645" checksum="6362DBA9E1B3BDBE" modified="2019-10-16" version="1">MNRQLPLTQQNLDQLPSQIARPTYDRSRLTTGIVHVGVGGFHRAHEAFYTDQLLESGGDPQWGICGVGLREPDRKMATILRDQDYLYTLIVKRPDGGIETRVIGSIVDFLMGCDDPAAVIDRMADPATKIVSLTITEGGYNVDPATGKFNASNPDAQHDIDHPLQPRLVFGFMTAALAKRRQQGLPAFTVQSCDNIQHNGELTRKMLIGFARLQDPQLADWIEQEVSFPNAMVDRITPVTSDADIDFLRTEFGLDDKWPVACEPFCQWVVEDDFSAGRPDWQDVGVQFVPDVTPYEKMKLRLLNAGHSVLGILGSVFGHETIDQAIGDDLFAQYLRQFFDREATPVLDAVAGIDLDEYKQTLIERFGNPKIRDSLSRICLESSSKLPVFLIPTIRENLASGGSIRYATLVLAAWCYYSDKQVDRHGKALEITDGLKAELHAAAKKTGDDPLAFLKVQSVFGDLAENERFTNTYTELIDRIYSNPDVTATMQAILSDESNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZZ6</accession>
    <name>A0A518IZZ6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Inositol 2-dehydrogenase</fullName>
            <ecNumber evidence="3">1.1.1.18</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">iolG_17</name>
        <name evidence="3" type="ORF">Mal33_46840</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.1.18" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050112">
        <property type="term" value="F:inositol 2-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043906">
        <property type="entry name" value="Gfo/Idh/MocA_OxRdtase_bact_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19051">
        <property type="entry name" value="GFO_IDH_MocA_C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GFO_IDH_MocA" evidence="1">
        <location>
            <begin position="34"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="GFO_IDH_MocA_C2" evidence="2">
        <location>
            <begin position="201"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="GFO_IDH_MocA_C2" evidence="2">
        <location>
            <begin position="366"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="438" mass="48576" checksum="07EEDB3F80F27327" modified="2019-10-16" version="1">MPIDRRNFIASAAAAGALSAAPAIHGAQKNATYRTALIGSGWWGMNILREAVASQRVKVVAICDVDEDKRDLAAEEIEDLCGDQAKTYGDFREMLDREEIDIVIIATPDHWHALNAIAALEKGCHVFVEKPTGHTIGESRAMVDVAQATGRIVQVGLHRRSGPHHVAANQFLRDGNVGTIGAVRMFVNSRGGPERPSRNSEPPETLDWDMYCGPAPLRPFNRKIHPGGFRHFLDFANGTLGDWGVHWLDQMLMWSEEKSPKSVYSTGGRPVFGPAVLSESEQTTDAPDSQVAVYQFESFTATWEHRKFAGHGPERHNVGCYFYGDRGTLHIGWRDGWTFYPSDSKKAIQHQDAQLQEPDGHNMQLLWADFLQAIESGKQPACSALIGHQATNLSLLGMLSLKLGRSIAWDGETETIPGDEEANRLLRREYRGPWQYPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J034</accession>
    <name>A0A518J034_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NPCBM/NEW2 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_47140</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.1060">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010496">
        <property type="entry name" value="3-keto-disaccharide_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013222">
        <property type="entry name" value="Glyco_hyd_98_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013428">
        <property type="entry name" value="Membrane-bound_put_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038637">
        <property type="entry name" value="NPCBM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011041">
        <property type="entry name" value="Quinoprot_gluc/sorb_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029010">
        <property type="entry name" value="ThuA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06439">
        <property type="entry name" value="DUF1080"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08305">
        <property type="entry name" value="NPCBM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06283">
        <property type="entry name" value="ThuA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00776">
        <property type="entry name" value="NPCBM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50952">
        <property type="entry name" value="SSF50952"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02604">
        <property type="entry name" value="Piru_Ver_Nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022171204" evidence="2">
        <location>
            <begin position="23"/>
            <end position="1336"/>
        </location>
    </feature>
    <feature type="domain" description="NPCBM" evidence="3">
        <location>
            <begin position="606"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="511"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="513"/>
            <end position="533"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV58690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1336" mass="145993" checksum="B8C5A867F2F190CC" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
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    <name>A0A518J0I1_9BACT</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
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    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="61" mass="6613" checksum="661BFE5A65AE8E1E" modified="2019-10-16" version="1">MPAQTNAGFVPPSLALVCEVNLRIRPLEIRGVVLSLSITASTINRHGYFPPLHKIKLSDGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0K8</accession>
    <name>A0A518J0K8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF1080 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_48600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="DUF1080"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="1" id="KW-0732">Signal</keyword>
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        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021756011" description="DUF1080 domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1080" evidence="2">
        <location>
            <begin position="148"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="325" mass="35368" checksum="1B7F575BBB4F6946" modified="2019-10-16" version="1" precursor="true">MNRIFALTISIAMLNVAVFADDNDLKDTYLDPATAPIDYKIQGEYEGTAGPEAVKFGVQVIALGDGKFRMVSYTGGLPNADRSHKDVKVEIDGELEGDAAVFANDLFKIEIANGELAVSTVADGILRGTLYKVQRESDTLGAKPPAGAVVLFDGSSADAFEGGKLQGDLLAANCFSREKFGDHTLHLEFRTPFKPKARGQARGNSGVYMQSRYELQVLDSFGLAGKNNECGGIYSIAEPNVNMCFPPLQWQTYDIDFTAARYDDQGNKTKNARATIRHNGVVIHDDLELPHGTPGRHPEGPEADALYLQGHGNPVVYRNIWVVKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0P2</accession>
    <name>A0A518J0P2_9BACT</name>
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            <fullName evidence="2">Uncharacterized protein</fullName>
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    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="48" mass="5160" checksum="47E7C8517A051C3B" modified="2019-10-16" version="1">MKAEAKRARRIAAKDAPPVVYDTEPEDDEASVADDDASNEDPIDAVDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0Q0</accession>
    <name>A0A518J0Q0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cysteine desulfuration protein SufE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">sufE</name>
        <name evidence="3" type="ORF">Mal33_49480</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
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            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SufE family.</text>
    </comment>
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        <property type="protein sequence ID" value="QDV58923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003808">
        <property type="entry name" value="Fe-S_metab-assoc_dom"/>
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    <dbReference type="PANTHER" id="PTHR43597">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02657">
        <property type="entry name" value="SufE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SufE" evidence="2">
        <location>
            <begin position="11"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="143" mass="15992" checksum="FAE177B4ED371B59" modified="2019-10-16" version="1">MQTITPDELREEFQEINDYDERLEYIIEFADGLPQMAAEHRVEPNRVQGCVSNVWLVASQRPTESADDSPILDFEADSDAVITRGLIAIIVALLSGKPAKEILAIDIDGLFTELDLQGHLTRSRSNGLRSMVRRVRELAEAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0W0</accession>
    <name>A0A518J0W0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">HTH-type transcriptional regulator LutR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">lutR</name>
        <name evidence="5" type="ORF">Mal33_49990</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011711">
        <property type="entry name" value="GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008920">
        <property type="entry name" value="TF_FadR/GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07729">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00895">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48008">
        <property type="entry name" value="SSF48008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="4">
        <location>
            <begin position="12"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV58974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="217" mass="24448" checksum="4E4681C146EEB1FD" modified="2019-10-16" version="1">MTTETSSNDVRNTARQKCYDALRRLLICGQITPGSRLPEVEWSERLEVHRGALREAMVLLEHDGLLTLGKKGGFFAPMLGDFEFEELMHARCVLESGAIKMAAQRRLKKEAFKPLLDLCETMQTLHDADMELGFCEADYLFHQALVALSGNSRLMKMYSHSAQLIFSLSAVEDLQTVRRKRLQTLGDHRELCRMIMSGETDAAIALLEKHMSASLSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0Y4</accession>
    <name>A0A518J0Y4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_50250</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="119"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="163" mass="17641" checksum="B35C6156D8ABD611" modified="2019-10-16" version="1">MMRFITLATLLAISWVAMTFTHEMGHIIGGWLGGATLIRYDIAPWSLPFSLHNPDPIPVLTLWAGPVFGVVFPVGLAALIRRPAAWFVADFCILANGTYLAAAWISGDQFLDTPRMLDAGVPRVAIALYCVLTIGGGYFRFRADCAAILQSPSSNDPKTNSAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J160</accession>
    <name>A0A518J160_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_50700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="84" mass="8989" checksum="4C3DBDEC812E55F4" modified="2019-10-16" version="1">MEQANATAGAPVHSMVTRRRCPECDGDNLEWGDSMRNTSGVVDGRLRMHDVACEFFLGCCDCSETVLVVAAGDVAAFLTAETYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1E1</accession>
    <name>A0A518J1E1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">zf-HC2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_51630</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041916">
        <property type="entry name" value="Anti_sigma_zinc_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027383">
        <property type="entry name" value="Znf_put"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13490">
        <property type="entry name" value="zf-HC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="zf-HC2" evidence="2">
        <location>
            <begin position="6"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV59137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="305" mass="32757" checksum="E2754CCF1880D4E9" modified="2019-10-16" version="1">MSTIDCKTVQPFLSAYHDGELAAGQAATVANHVESCESCAAELRAFESLGAAFAKAPIPAKPAELWLQIERELPSAPGPVTLSHRFGIWIRESPYGAGLVSMVASILLVLGFGLWYGGDSRGVKEMGGQGAMVMHGSKGHTHDGEMSAEHMDEFVSVMDDYLRQLPRDPEGAERMLQAKYDGEDVDADGAVRLVGYRPIVSGGLPEGYSLASTSVLKMPCCTCVKAVCKRSDGSTLVLFEHDDEETAWFGGRQQSMAMCGDKNCCLVDLDSSIAATWKQGSRSVTAVGVRDQDEVAKLVTWLDKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1I7</accession>
    <name>A0A518J1I7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Tryptophan--tRNA ligase</fullName>
            <ecNumber evidence="8">6.1.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Tryptophanyl-tRNA synthetase</fullName>
            <shortName evidence="8">TrpRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 10" type="primary">trpS</name>
        <name evidence="10" type="ORF">Mal33_52290</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the attachment of tryptophan to tRNA(Trp).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + L-tryptophan + tRNA(Trp) = AMP + diphosphate + H(+) + L-tryptophanyl-tRNA(Trp)</text>
            <dbReference type="Rhea" id="RHEA:24080"/>
            <dbReference type="Rhea" id="RHEA-COMP:9671"/>
            <dbReference type="Rhea" id="RHEA-COMP:9705"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78535"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.2"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8 9">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.2" evidence="8"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004830">
        <property type="term" value="F:tryptophan-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006436">
        <property type="term" value="P:tryptophanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="entry name" value="TrpRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00140_B">
        <property type="entry name" value="Trp_tRNA_synth_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002305">
        <property type="entry name" value="aa-tRNA-synth_Ic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002306">
        <property type="entry name" value="Trp-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024109">
        <property type="entry name" value="Trp-tRNA-ligase_bac-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00579">
        <property type="entry name" value="tRNA-synt_1b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01039">
        <property type="entry name" value="TRNASYNTHTRP"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00233">
        <property type="entry name" value="trpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 8 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="short sequence motif" description="'HIGH' region" evidence="8">
        <location>
            <begin position="9"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="8">
        <location>
            <begin position="189"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="8"/>
            <end position="10"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="16"/>
            <end position="17"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="131"/>
        </location>
        <ligand>
            <name>L-tryptophan</name>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="143"/>
            <end position="145"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="189"/>
            <end position="193"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV59201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="320" mass="35506" checksum="8AD3E0A068F179DE" modified="2019-10-16" version="1">MRVLSGIQPTGRFHWGNFFGAIRQYIDLQHTHDGFYFIADLHALTTVRDPQVLRQNVRDAALDLLALGLDPEKATLFLQSDVPEVSELSWLLMTGTPMGLLERCHAYKEKKERGIKADAGLFTYPVLMAADILAYDSDLVPVGADQIQHIEVCRDLAGSFNHAYGETFVLPKAKVLEDSAKVPGTDGQKMSKSYDNTLPLFGETKAIRKQIMRITTDSRPMEDPKDPEGDHLFDLLRLVGSQSDIDAMAETYRRGGFGYGEVKKAVAAASEEYFAAARQRRSDLEQNLDYVDQVLRGGAEKARGTAADVLSRAQHACGLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1L4</accession>
    <name>A0A518J1L4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_52560</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022066003" evidence="2">
        <location>
            <begin position="28"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV59228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="368" mass="38953" checksum="C26E46D8781C092C" modified="2019-10-16" version="1" precursor="true">MSIRNGRFGVMLAALLAISLGSATSYAASGLSPGPVELQSLGPMTFATSGVLIVGDPKAAAVYAIATEDKQVDGDLQKALPKDLRGQLAAAIGAESDALEIGDMAVNPETGNVTFSVKANNRCGLVRMNRDGQFQKINLDKIDHGRKQLPNPPADKISGEGRRKRNLRDQSITDVAYFDGKVIVSGLSAGDSPSAVVEFPFPFADNTIVSNVEIFHAAHGRVEDAAIQTFVPLNIDGEPSLLAGFTCTPLVNFPIGKLDGGEKVRGKTVAELGNRNRPIDMIVYEKEGVTHLLLSNTARGVMKVSTEKIDDGPGLTEPVRGGGTAGQPFEKIESLVDVTQMDKLSETHGIALIGKPGDAQRLQIFELP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1L5</accession>
    <name>A0A518J1L5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Selenocysteine synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_52470</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018319">
        <property type="entry name" value="SelA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03841">
        <property type="entry name" value="SelA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="468" mass="50404" checksum="09B628E325F75567" modified="2019-10-16" version="1">MNQPKQNLSEWASEFLEERLSQAAATMRKPELVNDLKLKIGDVMNHLPGSAAREVERLLDAARQHAAALADLIHPDNSINTASINASGTLFSGDCGVPSSVAVQHPLMFHATHQNQTARKGVQRALQTVAMKLSGQHALAADSVEAAIVAVAKAERPSVKIVVPRCQAIGLPSGISLPDLLRSAGCEVIEVGTVDGWSVDGLRRELGDDLGHCALVTADRIVDGAVRDPNPDGRPNQIMPELRRLMHVTSYVAPRSLEELVQPCLMTLQEACRDTLLVTGGDGLLGGPPLGILFGENARLQEITQTRDWCWLQADLTSQATMTLAMNSWGDGPAPEGSLLAMLETTHANLTDRAMRLKNRLEQAGYQATVRSDEVEARLWPVGNWTLPSVEIAIQRAADAEESAEEFADRLKRSRPMLLAKSGGETLVIDLRWVAPALDAKLAKTIIGTCESPTEDSATENVAESATT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1T4</accession>
    <name>A0A518J1T4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Formaldehyde-activating enzyme</fullName>
            <ecNumber evidence="2">4.3.3.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">fae</name>
        <name evidence="2" type="ORF">Mal33_53190</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="4.3.3.-" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016840">
        <property type="term" value="F:carbon-nitrogen lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016051">
        <property type="term" value="P:carbohydrate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014826">
        <property type="entry name" value="HCHO-activating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037075">
        <property type="entry name" value="HCHO-activating_enzyme_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08714">
        <property type="entry name" value="Fae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03126">
        <property type="entry name" value="one_C_fae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fae" evidence="1">
        <location>
            <begin position="5"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="164" mass="17231" checksum="103F2D66D0DFB71F" modified="2019-10-16" version="1">MQFYIGEALDGDGNEIAHIDLMIGSKDGPVGVAFANALANQSEGHTNLLAVLAPNVAVKPATVMVTKVTIKGMKQAVQMFGPAQAAVAKAVADSVGDGVIPADQAENLVIVCGVFIHPEAEDNKKIYDYNYSATKMAIVNAMGNKPSADEMLAQKDVDHPFKGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1X9</accession>
    <name>A0A518J1X9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Transmembrane exosortase (Exosortase_EpsH)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Mal33_53660</name>
    </gene>
    <organism evidence="10 11">
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            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="10 11">Mal33</strain>
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            <topology evidence="2">Multi-pass membrane protein</topology>
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</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
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                <person name="Rast P."/>
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            <dbReference type="EMBL" id="QDV59447.1"/>
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</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
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    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
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                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
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                <person name="Spormann A.M."/>
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                <person name="Amann R."/>
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                <person name="Ovreas L."/>
                <person name="Rohde M."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5 6">Mal33</strain>
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        <source>
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    </evidence>
    <sequence length="624" mass="68008" checksum="65B05047F6A25123" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
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                <person name="Rast P."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <comment type="subcellular location">
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        <property type="entry name" value="HTTM"/>
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        <property type="entry name" value="VKG_COase"/>
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    <dbReference type="Pfam" id="PF05090">
        <property type="entry name" value="VKG_Carbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00752">
        <property type="entry name" value="HTTM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="33"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="89"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="142"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="237"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="HTTM" evidence="6">
        <location>
            <begin position="24"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV54140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="318" mass="36520" checksum="4DFDC184C5024035" modified="2019-10-16" version="1">MNKPRRWIASYFAELTTLWDRFWFTPTAPHTLAAIRIAIGLMLLYTHLVLAYQLLAFVGTDAWVTTDTVRQLHENDYAWSYLWYVDSPAILWTHHLVTIAVTICFACGIFTRLTAPAAWFLQLMYMHRLTGALFGLDQMTTMITMYLMLTPCGSVWSVDAWLRRRREAAGRPSRWWLPSASPSIAANIGTRLLQLHLCVIYLFGGVSKMRGEMWWDGTATWFAVSNYEYQSMDMTWIVHYPILFAALSHATVLWETFYCALVWPRLTRPWVLLTAVMVHGGIALFLGMITFGVTMIIANAIFIPPAILQTLCRRHPKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMT1</accession>
    <name>A0A518IMT1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_03460</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010869">
        <property type="entry name" value="DUF1501"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07394">
        <property type="entry name" value="DUF1501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="435" mass="46832" checksum="CC71702D6BAA1385" modified="2019-10-16" version="1">MGISKTCDGVSRRDVLRVGALAAGGFSLTNYLSIAEAGEVQAGAKATSAIFINLPGGPSHIDTFDLKPEADDKVRGPFQPIKTNVPGIEFSEHLPKLAGCADKFAILRGVSHTLAAHALGQEYVNTGSRPLPSLEYPGFGSVVSMERPGDREIPGFVAVPNINQRPGFLGVQYAPLNTNATPRAGQPFAVRGIKLANGMTVDQMRRRQDLLSSLDRRMASIEKSSSLLQGLDRFSEQAYSMITSTRTRQAFDISKESENITKMFDDQTFSQSCLLATRLVESGVRFVGLTLGGWDTHVDNWTKLKTGLLPQFDAGLSGLLNSLAAKGLLESTAVFVTGEFGRTPKINTRSAEGGRDHYPRCMFMLMAGGGVRGGQVIGESDDTASAPRHEAITPDDVAASFYHNLGIDPTKEYHTETGRPITLVRDGNVIPQLFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INA6</accession>
    <name>A0A518INA6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cold-shock DNA-binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_05340</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04458">
        <property type="entry name" value="CSP_CDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002059">
        <property type="entry name" value="CSP_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00313">
        <property type="entry name" value="CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51857">
        <property type="entry name" value="CSD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CSD" evidence="2">
        <location>
            <begin position="13"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="119" mass="14189" checksum="C26FD71298D7F66E" modified="2019-10-16" version="1">MNIRYDDEYIQRKRVGEIRNIDPVKNFGFISGEDFRGDVFFHMSVWESDRNMLPEIGMIVEFEINQVHLQETDSLRATVVRRTDRPYTKQLDLKADESLTVKHHPNARKRKPVWRGKKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IND3</accession>
    <name>A0A518IND3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Response regulator PleD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_05590</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="122" mass="13361" checksum="AE8C7069F92637DB" modified="2019-10-16" version="1">MQTVLDIGNCSPDHSAIRTLIEGNFDARVVQAHGAADAMEILGRQEVALITVNRKLDRDYSDGMEIIRQLKNDPKTQAIPVMLITNFPEHQDAAMAIGAERGFGKLQLRAAETKQSLAAFLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INU0</accession>
    <name>A0A518INU0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_07190</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="420"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="485"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="518"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="228"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="333"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV54759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="539" mass="58693" checksum="1F0CEF384BED4F30" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP31</accession>
    <name>A0A518IP31_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ASCH domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_07930</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007374">
        <property type="entry name" value="ASCH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04266">
        <property type="entry name" value="ASCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="SSF88697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ASCH" evidence="1">
        <location>
            <begin position="8"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="115" mass="13226" checksum="F0BA78EDF138B235" modified="2019-10-16" version="1">MSQPTRALSIRQPHAEAIMRGIKQIEYRSSATKIRERIYIYAGLGRYDANDEAEWMDDYGITDVACDDLPRGVIVGTVELHDSNGGEWYLRRPQRATTLRKPENRANPVWFKPFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP32</accession>
    <name>A0A518IP32_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative S-adenosylmethionine-dependent methyltransferase/MSMEI_2290</fullName>
            <ecNumber evidence="2">2.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_07890</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.1.1.-" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="297" mass="32464" checksum="989E090653276024" modified="2019-10-16" version="1">MSTITEIESSADPKPTSADSATEANALGGESSFEKRDRELFDTIAGKYAAKDRSPSARPARRQRLLQTLAALPERSLHGKRILEVGCGAGYSVDYLPADYACYLGIDYSEMLIDLARAERQTDRATFATTNARDLKTDEPFDIIFMIGVLHHMDQMDEVVENLVSLLAPGGWLVVNEPQPSNPIVGIARRLRKQVDASYSDEQLELTGREMESCFADAGLTSLRQRPQGLLSTPFAEVPMNPSWLTAPASRIACGLDRGIEAIAGRLLTPLTWNVIVAGQKPIDPQSTTQNSRTPAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP47</accession>
    <name>A0A518IP47_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">4-hydroxy-tetrahydrodipicolinate reductase</fullName>
            <shortName evidence="9">HTPA reductase</shortName>
            <ecNumber evidence="9">1.17.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9 12" type="primary">dapB</name>
        <name evidence="12" type="ORF">Mal33_08380</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>(S)-2,3,4,5-tetrahydrodipicolinate + H2O + NAD(+) = (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:35323"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16845"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:67139"/>
            <dbReference type="EC" id="1.17.1.8"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>(S)-2,3,4,5-tetrahydrodipicolinate + H2O + NADP(+) = (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:35331"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16845"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:67139"/>
            <dbReference type="EC" id="1.17.1.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="9">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 4/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the DapB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.</text>
    </comment>
    <dbReference type="EC" id="1.17.1.8" evidence="9"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00018"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008839">
        <property type="term" value="F:4-hydroxy-tetrahydrodipicolinate reductase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016726">
        <property type="term" value="F:oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019877">
        <property type="term" value="P:diaminopimelate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00102">
        <property type="entry name" value="DapB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022663">
        <property type="entry name" value="DapB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000846">
        <property type="entry name" value="DapB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022664">
        <property type="entry name" value="DapB_N_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023940">
        <property type="entry name" value="DHDPR_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20836">
        <property type="entry name" value="PTHR20836"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05173">
        <property type="entry name" value="DapB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01113">
        <property type="entry name" value="DapB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000161">
        <property type="entry name" value="DHPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00036">
        <property type="entry name" value="dapB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01298">
        <property type="entry name" value="DAPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 9" id="KW-0220">Diaminopimelate biosynthesis</keyword>
    <keyword evidence="8 9" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="7 9" id="KW-0520">NAD</keyword>
    <keyword evidence="4 9" id="KW-0521">NADP</keyword>
    <keyword evidence="6 9 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DapB_N" evidence="10">
        <location>
            <begin position="1"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="DapB_C" evidence="11">
        <location>
            <begin position="114"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="(S)-2,3,4,5-tetrahydrodipicolinate binding" evidence="9">
        <location>
            <begin position="153"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="9">
        <location>
            <position position="143"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="9">
        <location>
            <position position="147"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="83"/>
            <end position="85"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="107"/>
            <end position="110"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="144"/>
        </location>
        <ligand>
            <name>(S)-2,3,4,5-tetrahydrodipicolinate</name>
            <dbReference type="ChEBI" id="CHEBI:16845"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF05173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QDV54873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="253" mass="26713" checksum="A03D494C8BA8FC64" modified="2019-10-16" version="1">MGRRVVALATADEAFQVIAAIDHQQHPLLGQDSGGLAGCDLNEVPLSADWPAECDAAIDFSLPDAVGSAVANCLESKTPLVIATTGLSDETQAAIAEAVKQISIVWAPSMSLAVNLTMKLAEQAAAALKNVPGGVDIEIIERHHRYKVDAPSGTALKFGELIADQLDGETKHVHGREGETGQRSLNEIGYHAVRVGDNTGEHTIVYGMLGETMELRVASSNRDCYASGALAAARWIQGRPPALYSMFDVLGLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP90</accession>
    <name>A0A518IP90_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Inositol 2-dehydrogenase</fullName>
            <ecNumber evidence="3">1.1.1.18</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">iolG_3</name>
        <name evidence="3" type="ORF">Mal33_08490</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.1.18" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050112">
        <property type="term" value="F:inositol 2-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043906">
        <property type="entry name" value="Gfo/Idh/MocA_OxRdtase_bact_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19051">
        <property type="entry name" value="GFO_IDH_MocA_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GFO_IDH_MocA" evidence="1">
        <location>
            <begin position="39"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="GFO_IDH_MocA_C2" evidence="2">
        <location>
            <begin position="196"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="445" mass="48547" checksum="55D3F41201EEC377" modified="2019-10-16" version="1">MKKNNSRRTFLKATTVASAGYWVAGGIAPKESLAANEEIRFACIGVGGKGSSDSADAGKAGKVVAICDIDDERLNKAGERFTDASKYYDFRKMLDEKDKSIDAVTVSTPDHCHGVATAAALALGKHCYTQKPLTRTIWESRRLGELAAENKCQTQMGNQGTANSGVREAAAMIKAGAVGDVKEVHVWTNRPVWPQGIGQPAAEEVPSYIHWDEWIGPAEKRPYSSAYHPFKWRGFWDFGTGALGDMACHTLNMPYMGCDLQNPTSVQATTSGHNKITYPSWSQIVFEFPANDWRGATQLYWYDGGKLPAQSLFAGSESFAKKGLSSSGCLVVGSKGSLYSPNDYGATFEMLGGAETKEVDYDRSPGHFRELAMAIKTGKEAKSNFPNYAGPLTETILLGNLAVFAADENEKQGEKISWNAKEMKVLGTDKYDWMVKPDLKNGYTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPB0</accession>
    <name>A0A518IPB0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_08840</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="64" mass="7126" checksum="EF28ACE7914EBEDD" modified="2019-10-16" version="1">MRKHRVTITLVISDDASANALILLLKALLKRLGRNQPVAVMASVARNQRHSVFCPHVENDDNHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPC6</accession>
    <name>A0A518IPC6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative oxidoreductase CzcO</fullName>
            <ecNumber evidence="1">1.-.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">czcO_1</name>
        <name evidence="1" type="ORF">Mal33_08930</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.-.-.-" evidence="1"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="523" mass="59514" checksum="841B0DE3699B8E0F" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPD0</accession>
    <name>A0A518IPD0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Type II secretion system protein G</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">pulG_1</name>
        <name evidence="1" type="ORF">Mal33_09040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011453">
        <property type="entry name" value="DUF1559"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07596">
        <property type="entry name" value="SBP_bac_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="299" mass="32983" checksum="436E3D97A1B9771A" modified="2019-10-16" version="1">MKRIHPLHGPRRGFTLVELLVVIAIIGILVGLLLPAVQAAREAARRMQCSNNMKQLGIALHNYHDINKRFPPCSIDGNGKIGIFVRLLPFMEQQAMFDQVRYDGNYVQNLPISLNRLDTLLCPSGPQLYSTSTAANEADCYTSHYYGNSGPVGTNGQTGQTYTRDTTRENASFGEYATDGIFQLRSNLRFADILDGTTNTIGIGELSYQKYGFYRAWTRGLYWYNGVALLSSKNHKWPINAAVNGGFTMTFNNGGYGSQHPGGCMMGMMDGSVRFLSETIDMTTYRAAASRASGEVQGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPL8</accession>
    <name>A0A518IPL8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Nitrogen regulatory protein P-II 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">glnK</name>
        <name evidence="1" type="ORF">Mal33_10140</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030234">
        <property type="term" value="F:enzyme regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006808">
        <property type="term" value="P:regulation of nitrogen utilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002187">
        <property type="entry name" value="N-reg_PII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011322">
        <property type="entry name" value="N-reg_PII-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015867">
        <property type="entry name" value="N-reg_PII/ATP_PRibTrfase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30115">
        <property type="entry name" value="PTHR30115"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00543">
        <property type="entry name" value="P-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00340">
        <property type="entry name" value="PIIGLNB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00938">
        <property type="entry name" value="P-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54913">
        <property type="entry name" value="SSF54913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51343">
        <property type="entry name" value="PII_GLNB_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="113" mass="12534" checksum="CC7659BC83EDEF9C" modified="2019-10-16" version="1">MKRIEAIIDAEHLEEVNAALEEIGVHRILVTEVRGFIRKQIQASGLDRSGSFFFVPKCKLDISVVDAHLRRAAHAIFAASNTRVLVDGKLFLEDMESEFTPQWGSAQLNGVAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPM9</accession>
    <name>A0A518IPM9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Spermidine synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_09950</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="248" mass="27740" checksum="AA628D2EED611FCC" modified="2019-10-16" version="1">MERPNFEILAYEDSPLGPLCLRRRELLSQPGTIVTEVTLNHEFLMSSLNTDSERQISNRAVEIHGGPNLKTLVGGLGLGYTAQELLKHENVASVDVIEYLPQVVDWLRQGLVPLSSELNAAEQLKIIAGDVYQRLTESPKDRYDLIVIDVDHSPSDQLGEEENGFYTRDGLLAAKAHLAEDGVLAVWSYAQSSQFSVALRETFESVHVEPVKTFNALVDHWQTDWLFFATDRQLDPAELPQPEQDAAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQF7</accession>
    <name>A0A518IQF7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Magnesium transporter MgtE</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">mgtE</name>
        <name evidence="9" type="ORF">Mal33_12880</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Acts as a magnesium transporter.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the SLC41A transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015095">
        <property type="term" value="F:magnesium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.60.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006668">
        <property type="entry name" value="Mg_transptr_MgtE_intracell_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038076">
        <property type="entry name" value="MgtE_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006669">
        <property type="entry name" value="MgtE_transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006667">
        <property type="entry name" value="SLC41_membr_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036739">
        <property type="entry name" value="SLC41_membr_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01769">
        <property type="entry name" value="MgtE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03448">
        <property type="entry name" value="MgtE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00924">
        <property type="entry name" value="MgtE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161093">
        <property type="entry name" value="SSF161093"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00400">
        <property type="entry name" value="mgtE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0129">CBS domain</keyword>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="285"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="359"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="386"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="424"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="8">
        <location>
            <begin position="137"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="8">
        <location>
            <begin position="202"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV55317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="448" mass="48001" checksum="876B0660212BCF67" modified="2019-10-16" version="1">MNQLQLDPATEDEAPEDAGIAEIANLVATGEMADAVVALDRLSPDSQAEAVASLSPELAANLMEHVVEASAVEIIDHLPTNVAALILDEVTSDHRADLIAELSEANAAEIIDQMTPEEAADARTLMQYASDTAGGLMITEYVSFQADQTVRDVIEDLAENADEYRHYDIQYSFVCDGERLVGVLPLLDLLLSKRATPLRDIMVANPISVLDTMSLDDVEDLLESHAFLGVPVIDAQGDLLGVVQRAAVEYARSEQQRSDYLKSQGIVGGEEVRSLPLLDRSKRRLSWLSVNILLNIMAASVIAFFQDTLESVIALAVFLPIISDMSGCSGNQAVAVSMRELSLGLVKPNEALRVWFKEISVGILNGFTLGLLIATAAMLWKGDAMLGFVVGFALCMNTMIAVSFGGVVPLILKRAGVDPAIASGPLLTTITDMCGFFLVLGLASLLLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQR6</accession>
    <name>A0A518IQR6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ECF sigma factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_14010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011517">
        <property type="entry name" value="RNA_pol_sigma70_ECF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07638">
        <property type="entry name" value="Sigma70_ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02999">
        <property type="entry name" value="Sig-70_X6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="115"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="187" mass="20558" checksum="FEDE4A7D95B59DC4" modified="2019-10-16" version="1">MPDVTRILHQLEAGDASAADELLPLVYAELRKLADQRLAQEKPGQTLQATALVHEAYVRLVDVDQSQDWDGRGHFFAAAAEAMRRILVENARSKQCIKRGGGMQRLDVDQVPLVAKEVKEDLLALDEALQRLAAVDAEAAKLVNLRYFGGFSNAQAASMMDISPRTADRIWAFARAWLFQALGGSNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IR81</accession>
    <name>A0A518IR81_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_15760</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021857">
        <property type="entry name" value="DUF3467"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11950">
        <property type="entry name" value="DUF3467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="128" mass="13764" checksum="D7DB5800060316DF" modified="2019-10-16" version="1">MTKDAETPEAPAAEAAAAPAAPAAQAQSQPVQVQVTDENAQACYANFCRVTGSPEELIIDFGLNPQPIGVPKDPINVNQRIIVNFFTAKRLLAALQMSVARHEAVFGVLETDINKRVRPAQQKQGENK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IR95</accession>
    <name>A0A518IR95_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ATP-dependent zinc metalloprotease FtsH</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ftsH_2</name>
        <name evidence="1" type="ORF">Mal33_15880</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037219">
        <property type="entry name" value="Peptidase_M41-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140990">
        <property type="entry name" value="SSF140990"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="166" mass="18575" checksum="9FBEF395B309F343" modified="2019-10-16" version="1">MSEISAYHEAGHAMMAMIAGARILSVTIEPDWDDGPQRHADIQIQWPTERFDSRELSEKLAMVALAGPAAEMIHTGDPYHPGLIAEWKSDWELAWEAAAPRFPDPRKRLAYLEQITARAYRILAQDDFWAALATIVDNLLAHETLEGEEVEEIVQQWIAVGGQAAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRB0</accession>
    <name>A0A518IRB0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transglutaminase-like superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_15810</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002931">
        <property type="entry name" value="Transglutaminase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01841">
        <property type="entry name" value="Transglut_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00460">
        <property type="entry name" value="TGc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TGc" evidence="1">
        <location>
            <begin position="183"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="302" mass="32982" checksum="7086071870B97BDE" modified="2019-10-16" version="1">MRDSLACASARLRVCRYNKAVSMKTIYVGCQLKYYVHTPTSFLLNISAAMNDFQRICNERIEVTPDQPLEQCQVGPLGNRLFRLIGQPGPLSIGYQAEVELRSAAVDSNNVGESNYSSLPPEVLIFLNPSRYCESDKLNRFAMNEFGWLLPGYSRVTAICNWTFDHLTYTPGSTGPSTTACDVLLQRAGVCRDYAHVAISLCRAMGIPARYVAGYAVHLQPPDFHGFFEAFLDGRWFLFDATRMAPVGGFVRIGTGRDAADVAFATLVGAAESVEMSVWANDSDSFGGGPGPDDVRSGLSSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRD3</accession>
    <name>A0A518IRD3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Phenylalanine--tRNA ligase beta subunit</fullName>
            <ecNumber evidence="11">6.1.1.20</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Phenylalanyl-tRNA synthetase beta subunit</fullName>
            <shortName evidence="11">PheRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11 14" type="primary">pheT</name>
        <name evidence="14" type="ORF">Mal33_16260</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + H(+) + L-phenylalanyl-tRNA(Phe)</text>
            <dbReference type="Rhea" id="RHEA:19413"/>
            <dbReference type="Rhea" id="RHEA-COMP:9668"/>
            <dbReference type="Rhea" id="RHEA-COMP:9699"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58095"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78531"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="11">Binds 2 magnesium ions per tetramer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 11">Tetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.</text>
    </comment>
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        <property type="protein sequence ID" value="QDV55648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="term" value="F:ATP binding"/>
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        <property type="term" value="F:magnesium ion binding"/>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004826">
        <property type="term" value="F:phenylalanine-tRNA ligase activity"/>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:phenylalanyl-tRNA aminoacylation"/>
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        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
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        <property type="entry name" value="B3/B4_tRNA-bd"/>
    </dbReference>
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        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005121">
        <property type="entry name" value="Fdx_antiC-bd"/>
    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR045060">
        <property type="entry name" value="Phe-tRNA-ligase_IIc_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004532">
        <property type="entry name" value="Phe-tRNA-ligase_IIc_bsu_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020825">
        <property type="entry name" value="Phe-tRNA_synthase-like_B3/B4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041616">
        <property type="entry name" value="PheRS_beta_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005147">
        <property type="entry name" value="tRNA_synthase_B5-dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10947">
        <property type="entry name" value="PTHR10947"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03483">
        <property type="entry name" value="B3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03484">
        <property type="entry name" value="B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03147">
        <property type="entry name" value="FDX-ACB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17759">
        <property type="entry name" value="tRNA_synthFbeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00873">
        <property type="entry name" value="B3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00874">
        <property type="entry name" value="B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00896">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="SSF54991"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00472">
        <property type="entry name" value="pheT_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51447">
        <property type="entry name" value="FDX_ACB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="7 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 11 14" id="KW-0436">Ligase</keyword>
    <keyword evidence="8 11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 11" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="B5" evidence="13">
        <location>
            <begin position="288"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="domain" description="FDX-ACB" evidence="12">
        <location>
            <begin position="578"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="342"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="348"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="351"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="352"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="HAMAP-Rule" id="MF_00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="QDV55648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="673" mass="73326" checksum="E6444D0ACD7FEA03" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRG4</accession>
    <name>A0A518IRG4_9BACT</name>
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        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">pknD_3</name>
        <name evidence="7" type="ORF">Mal33_16590</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="13"/>
    </dbReference>
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        <property type="entry name" value="SSF48452"/>
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    </dbReference>
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        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="147"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="123"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="327"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="512"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="123"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV55680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1603" mass="177515" checksum="09070A4D0C54C902" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRP4</accession>
    <name>A0A518IRP4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">MR_MLE_C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_17300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036849">
        <property type="entry name" value="Enolase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029017">
        <property type="entry name" value="Enolase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029065">
        <property type="entry name" value="Enolase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034593">
        <property type="entry name" value="Mandelate_racemase_DgoD-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48080">
        <property type="entry name" value="PTHR48080"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13378">
        <property type="entry name" value="MR_MLE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51604">
        <property type="entry name" value="SSF51604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54826">
        <property type="entry name" value="SSF54826"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MR_MLE_C" evidence="1">
        <location>
            <begin position="222"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="447" mass="48441" checksum="1C5A7A46BA5BF51D" modified="2019-10-16" version="1">MLSNIRICDLQTNITKHPYRTPMKFGGRVVSGVDVLEVRCTVETKSGRRAEGLGSMTMGNAWSWPSQVVSSDQTLAAIETLAQRHAAAAMEAKVEGHPLEICHTLAKLLRPIAAEVTQEAGLEEAMPQLACLLAASPLEAALFDAQGKALGTSSYRLLGKDYVGSDLQPYLGNDFAGHYLDEFVSPQPQSSMPIYHLVGALDPLTDADVDQPVGDGHPETLAAWIEADGLTHLKIKLAGDDLDWDIDRVARVSRVASESSRGATTDWRFSLDFNERCANQQYVIDMLQGVAKVSDDANGRIQYVEQPTHRDLARFPENTMHEVTKMLPVVIDESLVDLESLHLSRELGYSGIALKACKGHAEALLMGAAAQHYKLFLCVQDLTCIGANFLHSASLAAHIPTVAAIEGNGRQYCPAGNEGWEKKFPGMFEITDGTVETGLLNGPGLGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRU2</accession>
    <name>A0A518IRU2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_17810</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="361" mass="38712" checksum="A2429074D3BFBAB5" modified="2019-10-16" version="1">MHLDTNRSLLGDLHLAPPPTGPRSTSDREVPASEVRRAHGPAIPLRCPLFAYDLPWALLPPTTCALLARELTESAVVTSLLDLDVDEDRPADLVMCPYRPERYGVTIDDLSRAAFVDLRLNSEVGDGSVYTMDQLRRWDHRADSLPDSTVITGSRWPADVASPDKLGRKVEQLRTLAPQAAIFVAISPFHLQQDLPNLLAARPDGIVLRFDLDPTSPSVGNLIAAQTAACRRMIDASEAAGIALWVSAPTTSPLDLVKLLALGASAVSIDYLVLHNWPAADPAPASGDPHASYAHASALGHPSAGAATATRMISPIIDTLLNEALTYVHGLGVAHYSQLRPHMLACIDPTLAKRTGAMLVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IS36</accession>
    <name>A0A518IS36_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Inner membrane permease YgbN</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ygbN</name>
        <name evidence="2" type="ORF">Mal33_18860</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015128">
        <property type="term" value="F:gluconate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003474">
        <property type="entry name" value="Glcn_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30354">
        <property type="entry name" value="PTHR30354"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02447">
        <property type="entry name" value="GntP_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="5"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="163"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="201"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="257"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="308"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="337"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="373"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="461"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="487" mass="50726" checksum="11B329949C88C52D" modified="2019-10-16" version="1">MSIWWIVAIAVAVVLISILWLRLHAFLALAMAGFLVAVLTPDAALVDYADLQMEKSKGAWTQQEAASFVSSSGAQRLAQSFGEYAGKIGILIALASVVGSCLMHSGAAAVIIRRMLAIVGEARASYALAGSSFLLGIPVFFDTVFYLMVPLAKSLRRQVGKDYVLYILAILAGGSLAHSLVPPTPGPLAVAAELHIEIFDMMVGGLAICCCSSVLSLSAAAVINRFVDVPLRDDETPADEKSAGGPPSIDEVEGPPFWLALLPIALPVLLIAGGTAWNMWIGSFDSGAAPAWTDSLGRIVKLASDKNVALGIAAAMAMGLLRWAPVASDRNQLIGKALASGGVIILITSAGGAFGTMLRYAGIAEAVAEMTGSLPGLMLLPLAFLVTASIRTLQGSATVAMITAAGVLQGFANPEILPYHPVYLATAIGAGSKPIMWMADSGFWVICKMSGMTESEGLRTLAPMSIAMGISALIFTVLGAWLLPMNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IS91</accession>
    <name>A0A518IS91_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_19200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="99" mass="10913" checksum="4D47382052743817" modified="2019-10-16" version="1">MSNETLLNVFPTDDERRRLVVAIQRCEGDVDRLVLRQESFSQDVGWFTQSSMAIEPEQLPGLKMALTSNTARKLQRPCRSGGASPAVLSFSEAATSRVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IS99</accession>
    <name>A0A518IS99_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Aspartate carbamoyltransferase</fullName>
            <ecNumber evidence="3">2.1.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">pyrB_2</name>
        <name evidence="10" type="ORF">Mal33_19410</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>carbamoyl phosphate + L-aspartate = H(+) + N-carbamoyl-L-aspartate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20013"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:32814"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="EC" id="2.1.3.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the aspartate/ornithine carbamoyltransferase superfamily.</text>
    </comment>
    <dbReference type="EC" id="2.1.3.2" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00116"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016597">
        <property type="term" value="F:amino acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004070">
        <property type="term" value="F:aspartate carbamoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1370">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006132">
        <property type="entry name" value="Asp/Orn_carbamoyltranf_P-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006130">
        <property type="entry name" value="Asp/Orn_carbamoylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036901">
        <property type="entry name" value="Asp/Orn_carbamoylTrfase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002082">
        <property type="entry name" value="Asp_carbamoyltransf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006131">
        <property type="entry name" value="Asp_carbamoyltransf_Asp/Orn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11405:SF16">
        <property type="entry name" value="PTHR11405:SF16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00185">
        <property type="entry name" value="OTCace"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02729">
        <property type="entry name" value="OTCace_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00100">
        <property type="entry name" value="AOTCASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53671">
        <property type="entry name" value="SSF53671"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00097">
        <property type="entry name" value="CARBAMOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="OTCace_N" evidence="9">
        <location>
            <begin position="48"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="OTCace" evidence="8">
        <location>
            <begin position="205"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV55962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="358" mass="39481" checksum="314D646F24AD1216" modified="2019-10-16" version="1">MNTEQLRSLALQPNASNSKGQLLDPQRLLDATDGKIDREALEALAGQSILNPRQFDRRTVVALAQLAALLETRNVEMEKPLDGKIAITAFFEASTRTRLSFESALLRLDGKVLSVPDGQVTGIAKGESLADIGEMFNTYGDIVIMRHPDTNSIEEIQKNLQRPLINAGNGSGHHPTQALIDWYALLKWRPELCRPDCPPERRIHLGIIGTPGSMRAVKSFLRLSLMFAGAVSKITLVSEMADPVGLDLTEPIEQSPIPIEVTNDVQKVLKELDVVYVNSIAFLGDSYRNLDGRYKLELASDLKPGAVVMHPLARNDELSEDLDDTDHNLYFAQAAGAVFVRQALLVSVLQRLNRISDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISB1</accession>
    <name>A0A518ISB1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Asparagine synthetase [glutamine-hydrolyzing] 1</fullName>
            <ecNumber evidence="9">6.3.5.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">asnB_1</name>
        <name evidence="9" type="ORF">Mal33_19400</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the asparagine synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.4" evidence="9"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004066">
        <property type="term" value="F:asparagine synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006529">
        <property type="term" value="P:asparagine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01991">
        <property type="entry name" value="Asn_Synthase_B_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00712">
        <property type="entry name" value="AsnB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006426">
        <property type="entry name" value="Asn_synth_AEB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001962">
        <property type="entry name" value="Asn_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033738">
        <property type="entry name" value="AsnB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00733">
        <property type="entry name" value="Asn_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001589">
        <property type="entry name" value="Asn_synthetase_glu-h"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01536">
        <property type="entry name" value="asn_synth_AEB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0061">Asparagine biosynthesis</keyword>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 5" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="9" id="KW-0436">Ligase</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="8">
        <location>
            <begin position="2"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="active site" description="For GATase activity" evidence="5">
        <location>
            <position position="2"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="296"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for beta-aspartyl-AMP intermediate formation" evidence="7">
        <location>
            <position position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001589-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001589-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR001589-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV55961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="639" mass="72375" checksum="315AE48CDA7007D2" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISB3</accession>
    <name>A0A518ISB3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Arylsulfatase</fullName>
            <ecNumber evidence="4">3.1.6.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">atsA_14</name>
        <name evidence="4" type="ORF">Mal33_19640</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="PTM">
        <text evidence="1">The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.</text>
    </comment>
    <dbReference type="EC" id="3.1.6.1" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004065">
        <property type="term" value="F:arylsulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021844204" evidence="2">
        <location>
            <begin position="26"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase" evidence="3">
        <location>
            <begin position="31"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="modified residue" description="3-oxoalanine (Cys)" evidence="1">
        <location>
            <position position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR600917-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV55985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="485" mass="54090" checksum="6097FC67D97712EE" modified="2019-10-16" version="1" precursor="true">MINRVTIWASSIAIMLAVTGDVVQAADDRMPNIVFIMADDLGWADVGYNGAEFYETPNIDALCRSGMEFTDAYPGAANCMPSRSCIMSGMYTPRTKMWTPGMVSKGEQRYMRLLVPSRQKPKGDGKIPTVGSLEPETFSLARLLKQVDYKTLHLGKWHLGSGSGLGFDRNDVDGRGADLKKDHKFYGNKNVAQWLTDAAVEYIAENKDDPFFIYLNHFDVHTPINARAAVVDKYKRKLASKKWSRNWNPVYAAMIEAVDRSVGRLRHAIEENGIQQETLVIFTSDNGGYGRATWNTPLKGSKGGFYEGGIRTPLVMSWPGKIKPGSVCDTPVTGVDYMPTFAELTGAPLAKDQPLDGVSIVPLMMGNAIAPRAIYWHYPLYLNGEVQVKPIYGTDRMYWRGTPCSVVRMGDWKLMEFFETGSIELYNLRDDLGESTDLADQHPEKAAELLKVLKKWQVETDADIPRTLNPDFDPDYVPAGKKGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISD9</accession>
    <name>A0A518ISD9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_19840</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026405">
        <property type="entry name" value="Chlam/Ver/Plancto_rRNA"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04137">
        <property type="entry name" value="Chlam_Ver_rRNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="68" mass="7813" checksum="7C08ABC1D7C8C356" modified="2019-10-16" version="1">MTMDKSLKVQAGAIKSRNVLTRAERISRLQELDKWTEDSAVVGMAKVRVQKVSLKKKKKVKKEDDKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISG0</accession>
    <name>A0A518ISG0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Pyruvate carboxylase</fullName>
            <ecNumber evidence="3 8">6.4.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">cfiB</name>
        <name evidence="16" type="ORF">Mal33_20070</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>ATP + hydrogencarbonate + pyruvate = ADP + H(+) + oxaloacetate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20844"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.4.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>biotin</name>
            <dbReference type="ChEBI" id="CHEBI:57586"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <dbReference type="EC" id="6.4.1.1" evidence="3 8"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00138"/>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004736">
        <property type="term" value="F:pyruvate carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006090">
        <property type="term" value="P:pyruvate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005481">
        <property type="entry name" value="BC-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001882">
        <property type="entry name" value="Biotin_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011764">
        <property type="entry name" value="Biotin_carboxylation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005482">
        <property type="entry name" value="Biotin_COase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003379">
        <property type="entry name" value="Carboxylase_cons_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CbamoylP_synth_lsu-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000891">
        <property type="entry name" value="PYR_CT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005930">
        <property type="entry name" value="Pyruv_COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02785">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00289">
        <property type="entry name" value="Biotin_carb_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02786">
        <property type="entry name" value="CPSase_L_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00682">
        <property type="entry name" value="HMGL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02436">
        <property type="entry name" value="PYC_OADA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001594">
        <property type="entry name" value="Pyruv_carbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00878">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="SSF51246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01235">
        <property type="entry name" value="pyruv_carbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50979">
        <property type="entry name" value="BC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00188">
        <property type="entry name" value="BIOTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00866">
        <property type="entry name" value="CPSASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00867">
        <property type="entry name" value="CPSASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50991">
        <property type="entry name" value="PYR_CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 8 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 8" id="KW-0092">Biotin</keyword>
    <keyword evidence="4 8 16" id="KW-0436">Ligase</keyword>
    <keyword evidence="11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 8 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Biotin carboxylation" evidence="14">
        <location>
            <begin position="3"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="13">
        <location>
            <begin position="123"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="domain" description="Pyruvate carboxyltransferase" evidence="15">
        <location>
            <begin position="535"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="domain" description="Lipoyl-binding" evidence="12">
        <location>
            <begin position="1069"/>
            <end position="1146"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="296"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="203"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="238"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="544"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="616"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" description="via carbamate group" evidence="11">
        <location>
            <position position="713"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="742"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="744"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="877"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004742"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00013057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR001594"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR001594-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR001594-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
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    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="QDV56028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1147" mass="124578" checksum="00B08FF804FC4A25" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISZ4</accession>
    <name>A0A518ISZ4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phospho-2-dehydro-3-deoxyheptonate aldolase</fullName>
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        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">aroF</name>
        <name evidence="3" type="ORF">Mal33_21810</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
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            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
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            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.5.1.54" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003849">
        <property type="term" value="F:3-deoxy-7-phosphoheptulonate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016832">
        <property type="term" value="F:aldehyde-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006218">
        <property type="entry name" value="DAHP1/KDSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041071">
        <property type="entry name" value="DAHP_snth_FXD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006268">
        <property type="entry name" value="DAHP_syn_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18152">
        <property type="entry name" value="DAHP_snth_FXD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00793">
        <property type="entry name" value="DAHP_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01361">
        <property type="entry name" value="DAHP_synth_Bsub"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DAHP_snth_FXD" evidence="2">
        <location>
            <begin position="26"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="DAHP_synth_1" evidence="1">
        <location>
            <begin position="115"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="371" mass="38952" checksum="AB745D4EE392CEB3" modified="2019-10-16" version="1">MSRFNRAGRTALPRFVCSAPTATVLILILKSDATEPQIQHVIERVESLGFGAHLSRGTFRTIIGLIGDEQRLQAEPLSAIPGVAEVLPVMPAYKLASLDAHPLPSVIDVGGVPVGGGQLAMIAGPCAVEEPDRMLRIAKAVKAAGANIFRGGAYKPRTSPYSFQGLGEEGLKILRDVGDECGMPIVTEVTDPRNVETVAKYADLLQIGARNMQNFVLLTEAGQSSKPVLLKRGMSATIVDWLMSAEYVLAQGNPNVILCERGIKSFDPSTRNLFDVAAVPVVKGLSHLPVIVDPSHATGKPALIPPCALAGVAAGADGVHIEVHDQPEVAKSDGPQALLPDQYAEVAQQIAKLAALLGKTIAPLPAGKSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITD5</accession>
    <name>A0A518ITD5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Type II secretion system protein G</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">xcpT_4</name>
        <name evidence="1" type="ORF">Mal33_23150</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011453">
        <property type="entry name" value="DUF1559"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07596">
        <property type="entry name" value="SBP_bac_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="315" mass="34447" checksum="058F70EEA9DF790A" modified="2019-10-16" version="1">MLSSKHARPRGGFTLVELLVVIAIIGILVALLLPAVQAARAAARRTQCKNNCKQIGLALHNYHDSFRQFPAGWISYQGEFEPGWGWAAAILPFAEQNNVYEQIDFRLPIEDSVHDAVRETVLSMYICPSDIAPDQFLIAEGSGGHVHSHSASVVAPTSYAMSSAIVESVDHDGPHLFTVSKSNYVGVFGSFEIHDNPYRGDGAFFADSRLRFRDFVDGTSSTMMVGERFGRLGSAIWHGVIPEAAEPEARVVGVTDHSPNSDHMHFEDFSSEHVTGAHFTLADGSVRMISDTIDLDVYRALSTRQGGEPIQNASF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITG0</accession>
    <name>A0A518ITG0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alkyl hydroperoxide reductase AhpD</fullName>
            <ecNumber evidence="2">1.11.1.15</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ahpD</name>
        <name evidence="2" type="ORF">Mal33_23520</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.11.1.15" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051920">
        <property type="term" value="F:peroxiredoxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029032">
        <property type="entry name" value="AhpD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004675">
        <property type="entry name" value="AhpD_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003779">
        <property type="entry name" value="CMD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02627">
        <property type="entry name" value="CMD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69118">
        <property type="entry name" value="SSF69118"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00778">
        <property type="entry name" value="ahpD_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CMD" evidence="1">
        <location>
            <begin position="41"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="178" mass="19207" checksum="E0D5C8E0DC4BC8BD" modified="2019-10-16" version="1">MPRLKTIGPNEAQPPLKEIYDDLTSQMGKVVNIFQGMGNSPAALKAYLSMSAALAEGDLSPEDREIIYLAVSEQNGCHYCVSAHAMLAKRVGLADDAIRAARQFQSSDPKHESLLTFVRRVIASKGFVSDEELQAVKSAGYSDGQIAEAVGYIGLATFSNLFNHVNGTELDFPAAEKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITH5</accession>
    <name>A0A518ITH5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_23760</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="73" mass="8256" checksum="B28DF3CD5EAC6588" modified="2019-10-16" version="1">MLIQRNPRYGDVVQLLHMVLDRCGRKVLGKPKAWARWTLCSGRGIRTDCTDVGGAGEDRPPPQEREAPRRTGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITS3</accession>
    <name>A0A518ITS3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_24770</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="132" mass="14833" checksum="5F4568703F3B7A14" modified="2019-10-16" version="1">MQLNYGIESTIFEVKEMSKRERSLIGNPGSRDPLGDRSKASDEVERWVVVKYGPIETEHVDMPQFVDGIIVAAAVPLLRGVQIGMGPSRQLAIHDLYLRLTTNPELETSLPTWWQNHIEGARQRLAQPGRNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITZ5</accession>
    <name>A0A518ITZ5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_25470</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010869">
        <property type="entry name" value="DUF1501"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07394">
        <property type="entry name" value="DUF1501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="455" mass="49594" checksum="6A70E9DCCBD3A75A" modified="2019-10-16" version="1">MLTILGRSGGAGQYCDGVSRRNFIKVGGMTLGTLSLPQLLQAEAAKGEGHRSHKAVINVFLPGGPPHQDMWDLKQDAPSEIRGEFRPIGTSVPGIEICELFPKLAKQMEHCAIIRSVVGAKGPHYSDQCVTGWDARNNEPAGGWPSMGAWVSKLQGPAGNAMPPHVSLMYKTSHTPWGEPGAGGFLGLAHAPFRLMGGKGETSKIDNMVLKDITLERLQDRAGLLKSIDSLRRDLDSSGAMDGMDAFTSQALGILTSSKLADAMDLSKEDPATVERYGKGDPQFRADGAPKMVENLLIARRLVEAGARVVSLNFSRWDWHGQNFQRARQDMPMLDQALAALIQDLVERNLDKDVSVVCWGEFGRTPKINANAGRDHWPRVSTALLACGGMRTGQVIGSTNRLGEYAVDRPIQFQEVLATLYHNLGIDLNTVREFDLRGRPQYPVAQGIEPIRELV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITZ7</accession>
    <name>A0A518ITZ7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Neutral/alkaline non-lysosomal ceramidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_25530</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031329">
        <property type="entry name" value="NEUT/ALK_ceramidase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04734">
        <property type="entry name" value="Ceramidase_alk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021967057" evidence="1">
        <location>
            <begin position="24"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="domain" description="Ceramidase_alk" evidence="2">
        <location>
            <begin position="27"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="484" mass="52286" checksum="83534A4B62E8334B" modified="2019-10-16" version="1" precursor="true">MPLPTKLLRVAAFLFLVTTTCVADDLRVGVADVDITPLESYPMAGYFHERLSTGQRDPLRAKAIVMRDGETSCAVAFCDMLGVSRDLYEEVRDQAAKATGIDPDQTVVSATHAHTAPDYFAELYRVQQQPDSEASKKSYAKYLSNQIVAAIVQANAAAVPVSIACGQTNQETPVSFNRRFVMRDGSVATWQNHRNPKVVRAAGPIDPEIGLLMFRSAADDQPLGVMSNFALHLDTVGGTQWSADFPFYIEQALRKHLGEQTISLFGAGTCGDINHSNPNQKERNKCDMIGGSLATTIVDALPTLTKIESPRLQVSHAVVQLPLQEVSPLEIERAQQLIPAAEAGEKIAMMDRVAAYRALHLYQLRHGEPVPDITPRRQVHSLRGVGASLPVDVTTIALGDQAAIVFLPGEVFVDIGLAIKRGSPYPTTLVVELANSNETMYIPTRGAFAGGGYEVINSAVAPGSGEMLIESALTQLRQLATPGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IU60</accession>
    <name>A0A518IU60_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator rcp1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rcp1_1</name>
        <name evidence="3" type="ORF">Mal33_26100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="1"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="134" mass="15083" checksum="044DD14165FA2360" modified="2019-10-16" version="1">MFLLVEDDEVDVERFRRAMNSHRITAELLVANDGAEAIELLHNQAAGTQKLIVFLDLNMPGVNGFEFLQMLRADAGLRRTLVFILTSSNHQRDKQQAYDKNVAGYFVKSNLDALMNTVKSYSDSVEYPPPAYAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IU64</accession>
    <name>A0A518IU64_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Outer membrane efflux protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_26020</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="599"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="599"/>
            <end position="617"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="625" mass="67787" checksum="063BFC595C6BF186" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IU77</accession>
    <name>A0A518IU77_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Carboxypeptidase G2</fullName>
            <ecNumber evidence="7">3.4.17.11</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">cpg2_1</name>
        <name evidence="7" type="ORF">Mal33_26320</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="5">Binds 2 divalent metal cations per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase M42 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.17.11" evidence="7"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010162">
        <property type="entry name" value="PepT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008007">
        <property type="entry name" value="Peptidase_M42"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42994:SF2">
        <property type="entry name" value="PTHR42994:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001123">
        <property type="entry name" value="PepA_GA"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="2 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="M20_dimer" evidence="6">
        <location>
            <begin position="191"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="150"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="117"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="151"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR001123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR001123-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001123-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV56639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="397" mass="41701" checksum="67C0871431735E72" modified="2019-10-16" version="1">MSRSIPLDTQQAVDRVIRLMAIPGISGCETAVSEAIIAELTDAGAAIAQFSYDDANTRTRLAGEVGNLIFHLPGKSDLPARLLTAHMDTVPICEGAQPAREGDQIVSTDPATGLGADDRAGCAAILTAALEALKLKGDHPPLVFGWLIQEEVGLQGARNLDVGKIGDVGLAFNFDGGTVDKLTVGATGGERMEIKITGRPSHAGVAPEQGISAIAIASLAIARLHNDGWHGRIEKPEGRGTSNVGVIQGGQATNVVTPEVNLRVEARSHDSAMRTRIVDEIRSAFQWAATQVTAADGSVGQIEFSSHLDYDSFRIDDDAPSVRMAAAAVEQLGRKPYTELAGGGLDANWLYKHGIPAVTLGCGQRNIHTANETLEIDDYLDACRVAIALACDTTSGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUD4</accession>
    <name>A0A518IUD4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acetoacetate decarboxylase (ADC)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_27040</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.400.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010451">
        <property type="entry name" value="Acetoacetate_decarboxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023375">
        <property type="entry name" value="ADC_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06314">
        <property type="entry name" value="ADC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160104">
        <property type="entry name" value="SSF160104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0704">Schiff base</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV56706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1055" mass="117231" checksum="BEC82C473390B3A1" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUH6</accession>
    <name>A0A518IUH6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_27420</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="194"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="226"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="258" mass="28982" checksum="44C18F33FB67FBAF" modified="2019-10-16" version="1">MSPTKPKRQLLPPMWQLPEEFRHRLGSTAGRQRAMLADGHLLLVLHVVPGADDTTRTGRFFWRETSGTWHSSDSGAGPAALHKHLDQYAAALDASEQRETEALHADQYLQLLERLSPLLRASRNMLQVLEEARKEVPQDRDLIECRDRAYEISRTAELLYGDAKNAMDVAVVRRAEQQAEASDRMARASHRLNVLLAMFFPIATLAAMFSTVFTEGWRLSDSPVPFVMFVGVGLVSGLLLTLFITRPGGPEIGWKRPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUI3</accession>
    <name>A0A518IUI3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_27470</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="69" mass="8077" checksum="54C433ACA100EB01" modified="2019-10-16" version="1">MCGVDRWIRDRCQASVHPLRGKQRGGPNKCLTYPEYLYKLSPIGHRGDMRKFRIRLPPLAGGAIWHCWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUJ2</accession>
    <name>A0A518IUJ2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SnoaL-like domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_27630</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037401">
        <property type="entry name" value="SnoaL-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011944">
        <property type="entry name" value="Steroid_delta5-4_isomerase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12680">
        <property type="entry name" value="SnoaL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02246">
        <property type="entry name" value="TIGR02246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021740683" evidence="1">
        <location>
            <begin position="25"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="SnoaL-like" evidence="2">
        <location>
            <begin position="52"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="320" mass="34666" checksum="235C6E9C5976102D" modified="2019-10-16" version="1" precursor="true">MNHRFLTFIVVAMLGAIHSTAGFAQQPAIAPTGQKSAAPPTPSEAAIRAESEAFVAAFNKADAKAIAAFWTEEGEYIDASGRQMVGREAIEQDYSKFFAANPNVKIQIAIDSLRFLSDSIAIEDGRAIVDPLPQGAPGVSKYTAVHTKVDGKWLMASVRETWSETPITRQSMADFEWLIGAWVAEEHGNQSESVYSWVADKSFVQRIYTTTHADGTKTSGVQLIGWNPVQGRVQSWSFSPDGGHASGLWSPNERGWTAEMIGMTGDGTPTTSLIRIARLDDNACVWQSVQRTLGGVAIPDTDEVVIKRQSPPVASQPTAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUK5</accession>
    <name>A0A518IUK5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">HIRAN domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_27700</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016818">
        <property type="term" value="F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014905">
        <property type="entry name" value="HIRAN"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08797">
        <property type="entry name" value="HIRAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HIRAN" evidence="3">
        <location>
            <begin position="16"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV56771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="246" mass="27472" checksum="59C71943831FEB23" modified="2019-10-16" version="1">MASKTLRRHLDGPELFQLEVVGESHFQKNLQAILSRYESHRIPDRVTQRATARIVSEPTNKHDPNAVQVLIEDLLIGYLDRETAARIRKQLAHAGFDSIDATCSSLIVGGFNLQFGHVLYGVKLDIFTKSQRRRKAQDVPVTELTFFTETPAALAPNELLAYVGNAVKFWSSPDTPSRIHIYCRGGVGGDGKLGTVPKDYIIPIQRHLSAGLEFDATIIAQSDQRWQIRCRLIQGYSVFEFVGLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUM0</accession>
    <name>A0A518IUM0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_27850</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032307">
        <property type="entry name" value="PepSY_TM-like_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40115">
        <property type="entry name" value="PTHR40115"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16357">
        <property type="entry name" value="PepSY_TM_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="149"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="180"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="202" mass="22188" checksum="5A568B3EA0726FC2" modified="2019-10-16" version="1">MPPDPKPSRWLYRKSAAAFRWLHIYLSMLSFASLMFFALTGITLNHPTWFGGSVQNVVDQSGQLPTQLLAGEVDELEIAETLRAEHRLKGRVKEFETDDYECMLVFKSPGYAADVFIDRETGNYSLTVTSSNAVAIMNDLHKGRDSGPAWSLLIDGSAILMAIMSLSGFGLLFYLKKRRVAGVLTALAGTIAVLAAWILGVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUS9</accession>
    <name>A0A518IUS9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">Dihydrofolate reductase</fullName>
            <ecNumber evidence="3 4">1.5.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">folA</name>
        <name evidence="6" type="ORF">Mal33_28400</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>(6S)-5,6,7,8-tetrahydrofolate + NADP(+) = 7,8-dihydrofolate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:15009"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57451"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.5.1.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 4">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 5,6,7,8-tetrahydrofolate from 7,8-dihydrofolate: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the dihydrofolate reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.3" evidence="3 4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00077">
        <property type="reaction ID" value="UER00158"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004146">
        <property type="term" value="F:dihydrofolate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006545">
        <property type="term" value="P:glycine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00209">
        <property type="entry name" value="DHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012259">
        <property type="entry name" value="DHFR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024072">
        <property type="entry name" value="DHFR-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001796">
        <property type="entry name" value="DHFR_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48069">
        <property type="entry name" value="PTHR48069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00186">
        <property type="entry name" value="DHFR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000194">
        <property type="entry name" value="DHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53597">
        <property type="entry name" value="SSF53597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51330">
        <property type="entry name" value="DHFR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="4" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="4 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DHFR" evidence="5">
        <location>
            <begin position="1"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR000194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV56839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="156" mass="17473" checksum="8B19F0D7A2053C79" modified="2019-10-16" version="1">MIIISAMSEDRVIGSQNGMPWNVPAEYQQYLDFVAGQTVIMGRKTFEIFGKDVAPETSLIVVSRSAELDDVPVATTFDKAVAMAKDLGKQIFIAGGSSIYEQALAVADQMYLSTIHGEYRGDAYFPAFDADNWQIVETREQPQFTFRRWKRTTASQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUW9</accession>
    <name>A0A518IUW9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Peptidase_M78 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_28780</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010359">
        <property type="entry name" value="IrrE_HExxH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06114">
        <property type="entry name" value="Peptidase_M78"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M78" evidence="1">
        <location>
            <begin position="37"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="327" mass="36564" checksum="66BBAAE754DFAAF7" modified="2019-10-16" version="1">MRQPGDQTITVGHVVVSLDEAIELTRSHYPNGPEKLAEHLGVPVLEASLVGAAGWCIKGRKPRIRIDNSTSPSRRRFTLAHELAHLVLGTDSELESKPFQTDIKEEREADRLASQFLVPDDRLEQFVGGHLPVDAKTLQRIAKDAKVSPVMAACRVASASERLGLLNAAVAYFENEKEVWQYSENLQFDEGEPSDLMREAIAAKPQLARSDNGDGKINVCSLLETQYYQLLLVQLLSPEDAVIESAEETRRRLAERVFGSDESFQQSVAALLGNVKKKCSGKTLNEAVAWFEETYVGTKYTGDRYERLSSDEGREYVRIHLSRWFSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IV28</accession>
    <name>A0A518IV28_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">cheA</name>
        <name evidence="10" type="ORF">Mal33_29500</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00088">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.560">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004105">
        <property type="entry name" value="CheA-like_dim"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037006">
        <property type="entry name" value="CheA-like_homodim_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036061">
        <property type="entry name" value="CheW-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002545">
        <property type="entry name" value="CheW-lke_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036641">
        <property type="entry name" value="HPT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008207">
        <property type="entry name" value="Sig_transdc_His_kin_Hpt_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01584">
        <property type="entry name" value="CheW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02895">
        <property type="entry name" value="H-kinase_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01627">
        <property type="entry name" value="Hpt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00260">
        <property type="entry name" value="CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01231">
        <property type="entry name" value="H-kinase_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00073">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47226">
        <property type="entry name" value="SSF47226"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50341">
        <property type="entry name" value="SSF50341"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50851">
        <property type="entry name" value="CHEW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50894">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HPt" evidence="9">
        <location>
            <begin position="1"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="6">
        <location>
            <begin position="258"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="domain" description="CheW-like" evidence="8">
        <location>
            <begin position="499"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="domain" description="CheW-like" evidence="8">
        <location>
            <begin position="670"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="7">
        <location>
            <begin position="817"/>
            <end position="935"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="132"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="222"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="234"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphohistidine" evidence="3">
        <location>
            <position position="50"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="4">
        <location>
            <position position="868"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV56949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="951" mass="102608" checksum="138C67E4C0906337" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IV58</accession>
    <name>A0A518IV58_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Fumarate hydratase class II</fullName>
            <shortName evidence="2">Fumarase C</shortName>
            <ecNumber evidence="2">4.2.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Aerobic fumarase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">Iron-independent fumarase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2 5" type="primary">fumC</name>
        <name evidence="5" type="ORF">Mal33_29690</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>(S)-malate = fumarate + H2O</text>
            <dbReference type="Rhea" id="RHEA:12460"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="EC" id="4.2.1.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate metabolism; tricarboxylic acid cycle; (S)-malate from fumarate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="2">There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.2" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00223">
        <property type="reaction ID" value="UER01007"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045239">
        <property type="term" value="C:tricarboxylic acid cycle enzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="F:fumarate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="term" value="P:fumarate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01362">
        <property type="entry name" value="Fumarase_classII"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00743">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005677">
        <property type="entry name" value="Fum_hydII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018951">
        <property type="entry name" value="Fumarase_C_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020557">
        <property type="entry name" value="Fumarate_lyase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000362">
        <property type="entry name" value="Fumarate_lyase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022761">
        <property type="entry name" value="Fumarate_lyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11444">
        <property type="entry name" value="PTHR11444"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10415">
        <property type="entry name" value="FumaraseC_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00206">
        <property type="entry name" value="Lyase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00149">
        <property type="entry name" value="FUMRATELYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="SSF48557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00163">
        <property type="entry name" value="FUMARATE_LYASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Lyase_1" evidence="3">
        <location>
            <begin position="12"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="domain" description="FumaraseC_C" evidence="4">
        <location>
            <begin position="419"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="106"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding (B site)" evidence="2">
        <location>
            <begin position="138"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="148"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="333"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="2">
        <location>
            <position position="197"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="327"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="328"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="2">
        <location>
            <position position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV56968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="474" mass="51289" checksum="6F4C4984772022EB" modified="2019-10-16" version="1">MSEYRVERDSMGEVQVPAEAYYGAQTQRAVENFPISGWRLPGPMIQAMGLVKFAAARANYDLGKLTGSGMNPLTEHDVECLSKACREVADGGLADQFPIDVFQTGSGTSSNMNVNEVISNRAIELAGGDRFAEKKTIHPNDHVNMGQSTNDTFPTAIHVAVGIEIKERLIPALQRLRDSLQEKATAWDQLIKIGRTHLMDATPLRLGQEIGGFVRQIDLSIGRAQSAIAAVCELPVGGTAVGTGINTHPEFGRRVSEILASETNIDFVEAENHFEANAQRDGLVECHGQLKCIAQTLFNVSNNIRWLGSGPRCGFFELKLPSRQPGSSIMPGKVNPVMCESMMQLNARVVGNDACITMSGATGGNFQLNIMMPVMAQTTLESIHLLSAGTEAFVDFCVAELEANPEACEAAVEQSLSMCTSLNPLIGYDMAAKLAKEAFATGKTIRELCREKGILPEETLTEALDPMSMTEPHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVG8</accession>
    <name>A0A518IVG8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Sensor histidine kinase RcsC</fullName>
            <ecNumber evidence="7">2.7.13.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rcsC</name>
        <name evidence="7" type="ORF">Mal33_30850</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.13.3" evidence="7"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004673">
        <property type="term" value="F:protein histidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.160">
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
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        <property type="entry name" value="HPT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008207">
        <property type="entry name" value="Sig_transdc_His_kin_Hpt_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01627">
        <property type="entry name" value="Hpt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00073">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47226">
        <property type="entry name" value="SSF47226"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="16"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="42"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="5">
        <location>
            <begin position="169"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="domain" description="HPt" evidence="6">
        <location>
            <begin position="325"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="141"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="218"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphohistidine" evidence="1">
        <location>
            <position position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV57084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="426" mass="46482" checksum="653568B2A9478A03" modified="2019-10-16" version="1">MNETPPDPIAHLRHRCLISIGAIVVISLIAQTAVAWGTAASIGLIETIFALTMLAVLIEVFFVFEPAVRTLQTQFLDLQRMLATAQEHSNPPSTDQVKPQEVFAVYREANETPRQPSQQIAAILIPQAAEATVSENVQADHPTSNALSTNTLSTNALPAPREDNAMTPKILLVEDNQINQMLAQEVLVSNDWQCDIAENGVEALDAIGVKTFDLILMDCQMPVMDGFSLTREIRARQLDGRLTSRCPIIAVTANALTGDRQKCIDAGMDDYLAKPFNPNQLTEIVEQWLPASTPRNPPRAIAADPAPEAPLPFVRQEFMERCMGDLGFAESLLESFQSDSLARVDEIVQHARQRNATAAGNAAHTLKGMAGILAAHPLQSIAADIEQAGRQDQLDQIDDLIDDLQNEVARCLAYIPKLTQGELESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVL1</accession>
    <name>A0A518IVL1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4261 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_31180</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025357">
        <property type="entry name" value="DUF4261"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14080">
        <property type="entry name" value="DUF4261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4261" evidence="2">
        <location>
            <begin position="220"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="292"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="340" mass="38095" checksum="F6D0E23BBAA3EFB4" modified="2019-10-16" version="1">MPKGFFSQGLCILLSEPVSLDRIAQALRGFEIVGQPTGGDDELIDLPSLLLGFRPDVDGQVLLSVVENRWPDEMGDPQEQPDVFVAWSLGQFGPLAYPGCLERATEQAWAWEECREATQKHTCFIRVLCSYVIGVADEDAPLLPEDYDAIDEMEYLTKIAAALLTIPEAICYFNPGGEVLRDEDGLREGLNYAWSHHLPPLDMWTNVRLFRATDEWSLMDTVGNGQFDLPDVEAAYLADKYEATEVEGFLRNASLYMLKEGDVIEEDDTADGPGDIVWRAILCDDALTDPPRPTVRWFPDDGSEAPTELTDTGLSDDEIEEQLDELMDFEDPEDDNEMPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVN2</accession>
    <name>A0A518IVN2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_31380</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="119" mass="13325" checksum="79D74DA40444B764" modified="2019-10-16" version="1">MSNEKNIEVEGQLAELTKLCCDSLEADRESLPERIEPLLKSLLMSGFERQKKQPLGVELEARILDACEGRSTQRGAEIRGVANQVQRKYDYLVRWESSHPKDPQAEPAQPANISSATDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVT1</accession>
    <name>A0A518IVT1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_31860</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022152122" evidence="1">
        <location>
            <begin position="23"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="323" mass="36279" checksum="B50B7311298C85A8" modified="2019-10-16" version="1" precursor="true">MRWSIAKAVIIGLVLLSNVAVAQPLAEESLILSTQCGRFQLVLGRIKLDCFHYKKVRLHQATAAPSEDEEFLFVTANHGTPSLHYVRHLGQSKVTIDTTQNDCIRIEAKHQLPTDRTETLLIQQQASGPIEITHEIGEQSRQIQTASFWHLIAEEPELFETAVAPLLSLMFDRYRMDEFSDAIDQRLRAQAARSPEITKASVEQAVGQLADPDRRQRLAAQRQLASAGVGILPLLNQIDNKRLDAEQRQLIGKLKQRLTIDRHDTPDRVAAWLATDRGYWLRVSQDWTPQQRSDAHRYLVATCGRGLDVDPSAVAVRAPIAGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVW6</accession>
    <name>A0A518IVW6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thioredoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">trxA_4</name>
        <name evidence="6" type="ORF">Mal33_32360</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the thioredoxin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005746">
        <property type="entry name" value="Thioredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000077">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01068">
        <property type="entry name" value="thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2 4" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="5">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="4">
        <location>
            <begin position="33"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR000077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000077-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV57232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="108" mass="11550" checksum="551C3ECFA5416233" modified="2019-10-16" version="1">MAGNVAEFTDQNFDTEVLQSDAPVLVDFWAPWCGPCRQIAPMIEELAGENPDLKIGKVNIDENPGAAQKYGVSSIPTILVFKNGEISESFVGVRPKGSLQAALDTAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWG1</accession>
    <name>A0A518IWG1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_34480</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="415" mass="44509" checksum="8B36F64A69B7AD2A" modified="2019-10-16" version="1">MPSSHDLPASGDPDPQVIPWLSSPEALEAIDRAEAAGQATVARTAALRRKIGPDRAAAVLSAAAARGKAIDKWGTGPWLVTDRGIQQATDRAIARYKSRRVPAGLEIFDWCCGVGGEAMQLSDRGPLTAIDRDPKIAEMARHNLGVHREQQAASDVAGWEFRSTVICDDVFAHHPPAAAWLNLDPDRRSESNTAGTSRATHCDYLQPPLSDWLPVAKQVAGASIKLAPATQLPEECHELGEREWISHRGSCRQQVLWLGEASPPGTIRATVVTGDDSATSFAVDQPQLCDETDTCEAFAFDLDPAVRAAGLSESYAAAKGLRALGGPAGFFTAQQNDVDALAQPFEVLWHGVADMKKLRQAIAAIDGCVSEVKIRGLDWKPPTIIKKLGRREGKKLTLLASRIGSYCGAILAVRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWH6</accession>
    <name>A0A518IWH6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 7">6,7-dimethyl-8-ribityllumazine synthase</fullName>
            <shortName evidence="7">DMRL synthase</shortName>
            <shortName evidence="7">LS</shortName>
            <shortName evidence="7">Lumazine synthase</shortName>
            <ecNumber evidence="4 7">2.5.1.78</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 8" type="primary">ribH</name>
        <name evidence="8" type="ORF">Mal33_34430</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>(2S)-2-hydroxy-3-oxobutyl phosphate + 5-amino-6-(D-ribitylamino)uracil = 6,7-dimethyl-8-(1-D-ribityl)lumazine + H(+) + 2 H2O + phosphate</text>
            <dbReference type="Rhea" id="RHEA:26152"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15934"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58201"/>
            <dbReference type="ChEBI" id="CHEBI:58830"/>
            <dbReference type="EC" id="2.5.1.78"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Cofactor biosynthesis; riboflavin biosynthesis; riboflavin from 2-hydroxy-3-oxobutyl phosphate and 5-amino-6-(D-ribitylamino)uracil: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the DMRL synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.78" evidence="4 7"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00275">
        <property type="reaction ID" value="UER00404"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009349">
        <property type="term" value="C:riboflavin synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000906">
        <property type="term" value="F:6,7-dimethyl-8-ribityllumazine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09209">
        <property type="entry name" value="Lumazine_synthase-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.960">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00178">
        <property type="entry name" value="Lumazine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034964">
        <property type="entry name" value="LS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002180">
        <property type="entry name" value="LS/RS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036467">
        <property type="entry name" value="LS/RS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21058">
        <property type="entry name" value="PTHR21058"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00885">
        <property type="entry name" value="DMRL_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52121">
        <property type="entry name" value="SSF52121"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00114">
        <property type="entry name" value="lumazine-synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0686">Riboflavin biosynthesis</keyword>
    <keyword evidence="6 7 8" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="5-amino-6-(D-ribitylamino)uracil binding" evidence="7">
        <location>
            <begin position="58"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="5-amino-6-(D-ribitylamino)uracil binding" evidence="7">
        <location>
            <begin position="82"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="1-deoxy-L-glycero-tetrulose 4-phosphate binding" evidence="7">
        <location>
            <begin position="87"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="90"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="24"/>
        </location>
        <ligand>
            <name>5-amino-6-(D-ribitylamino)uracil</name>
            <dbReference type="ChEBI" id="CHEBI:15934"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>5-amino-6-(D-ribitylamino)uracil</name>
            <dbReference type="ChEBI" id="CHEBI:15934"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>(2S)-2-hydroxy-3-oxobutyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58830"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV57433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="167" mass="17849" checksum="C7CBD282AF184208" modified="2019-10-16" version="1">MKTEINGTQGPLPEGKVAIVVSRYNESITGQLLQGARETLQAAGLAEEDIQVIWVSGAWELPLPTSYAARRKETLAVITLGAVIKGETTHDEHINRSVCNALMDIGLGTGKPVLLGLLTCNTVDQAIQRAGGNMGNKGSECAEAALEMIRVVDQMQDQGTPRVGFHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWS1</accession>
    <name>A0A518IWS1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AP_endonuc_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_35370</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013022">
        <property type="entry name" value="Xyl_isomerase-like_TIM-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01261">
        <property type="entry name" value="AP_endonuc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="SSF51658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022127485" description="AP_endonuc_2 domain-containing protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="domain" description="AP_endonuc_2" evidence="2">
        <location>
            <begin position="115"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="303" mass="33757" checksum="0A115EBECE3EA6DD" modified="2019-10-16" version="1" precursor="true">MKYNRRVALGALAAGLTAGWTQADENKASADSPSPWGPLCVFAKPLQMLSFSELADLLVKQQWDGIEATVRKGGQVEPAKVADQLPKLVDALAAKEKQVVLFASDVNSVDQRLTEPTLRAAAKAGIRYYRMAYYRYDLDQPILPQLDKFTRQVEQLVQLNRELGITALYQNHAGTRYCGAGLWDLYRIAADQPKEQLAVAFDIRHATVEAGMSWPIHWSMLRAHVGALYCKDFRWNEAKVENVPLGSGLVASSFYDALRKDPIAGIPVSVHMEYIDHRDPQLAAQRIAAVADDRRAIRRLLGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWV4</accession>
    <name>A0A518IWV4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_35810</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021781782" evidence="2">
        <location>
            <begin position="31"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="393" mass="42108" checksum="FA46ABCD3EB2AEC7" modified="2019-10-16" version="1" precursor="true">MKNTLYRSQAFRILGLVGLLSIAISSVASAASDDVTPTVREAMVKLSDEIARYIAADPDTKGQVAIGAFQGPSSSGAGARIVQSLKENLKSKCEIVDVGAAYTVSGRFMGQKLDGQFVTIIEAEIGDALGNTVQKLRRKVVTAIEEGLAFFGPSSVDLSAQPQAAKADKPASEKPESDSTAATEMLVSSIVKPETHLDANRKTRMNPADGSPYGLEIALKQADGKYHSLPITETDGVATVDLQADQIYAVRLFNDSARPVGCRLTIDGINTFALSLDANYRGKETIMELQPNAKFLIKGWHHTGDLSHEFRISNYADTPAAQFGVFDGVGMLTATFFETTAAQGYSATREFATAVGDEVEMRYRDGQSKFGKPIAAVSVRYVRPVAPTDLPLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IX29</accession>
    <name>A0A518IX29_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Coenzyme A disulfide reductase</fullName>
            <ecNumber evidence="3">1.8.1.14</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">cdr</name>
        <name evidence="3" type="ORF">Mal33_36570</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="1.8.1.14" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050451">
        <property type="term" value="F:CoA-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF55424"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="2">
        <location>
            <begin position="463"/>
            <end position="550"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="550" mass="59085" checksum="0FD69B6B47F68AE5" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IX39</accession>
    <name>A0A518IX39_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Fatty-acid--CoA ligase fadD21</fullName>
            <ecNumber evidence="5">6.2.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_36670</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="6.2.1.-" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008610">
        <property type="term" value="P:lipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05931">
        <property type="entry name" value="FAAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001917">
        <property type="entry name" value="Aminotrans_II_pyridoxalP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040097">
        <property type="entry name" value="FAAL/FAAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AA_TRANSFER_CLASS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="4">
        <location>
            <begin position="603"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="582"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="582"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="2">
        <location>
            <position position="641"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV57654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1117" mass="122011" checksum="949193751857B943" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXH3</accession>
    <name>A0A518IXH3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 8">DNA-directed RNA polymerase subunit beta</fullName>
            <shortName evidence="6">RNAP subunit beta</shortName>
            <ecNumber evidence="6 8">2.7.7.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">RNA polymerase subunit beta</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Transcriptase subunit beta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 15" type="primary">rpoB</name>
        <name evidence="15" type="ORF">Mal33_37910</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 8">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6 8">
            <text>a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="6 8">The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the RNA polymerase beta chain family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="6 8"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032549">
        <property type="term" value="F:ribonucleoside binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00653">
        <property type="entry name" value="RNA_pol_B_RPB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.270.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01321">
        <property type="entry name" value="RNApol_bact_RpoB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042107">
        <property type="entry name" value="DNA-dir_RNA_pol_bsu_ext_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019462">
        <property type="entry name" value="DNA-dir_RNA_pol_bsu_external_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015712">
        <property type="entry name" value="DNA-dir_RNA_pol_su2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007120">
        <property type="entry name" value="DNA-dir_RNAP_su2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037033">
        <property type="entry name" value="DNA-dir_RNAP_su2_hyb_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010243">
        <property type="entry name" value="RNA_pol_bsu_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007121">
        <property type="entry name" value="RNA_pol_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007644">
        <property type="entry name" value="RNA_pol_bsu_protrusion"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007642">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037034">
        <property type="entry name" value="RNA_pol_Rpb2_2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007645">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007641">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014724">
        <property type="entry name" value="RNA_pol_RPB2_OB-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20856">
        <property type="entry name" value="PTHR20856"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04563">
        <property type="entry name" value="RNA_pol_Rpb2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04561">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04565">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10385">
        <property type="entry name" value="RNA_pol_Rpb2_45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00562">
        <property type="entry name" value="RNA_pol_Rpb2_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04560">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02013">
        <property type="entry name" value="rpoB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01166">
        <property type="entry name" value="RNA_POL_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6 8" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="3 6 8" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RNA_pol_Rpb2_1" evidence="12">
        <location>
            <begin position="29"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_Rpb2_2" evidence="11">
        <location>
            <begin position="299"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_Rpb2_3" evidence="13">
        <location>
            <begin position="462"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_Rpb2_45" evidence="14">
        <location>
            <begin position="540"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_Rpb2_6" evidence="9">
        <location>
            <begin position="667"/>
            <end position="1160"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_Rpb2_7" evidence="10">
        <location>
            <begin position="1162"/>
            <end position="1236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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    </evidence>
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        </source>
    </evidence>
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    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="RuleBase" id="RU363031"/>
        </source>
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        <source>
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        </source>
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        <source>
            <dbReference type="Pfam" id="PF04560"/>
        </source>
    </evidence>
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        <source>
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        </source>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF04565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF10385"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="QDV57777.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1240" mass="138304" checksum="90AD1974CB1F2737" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IY50</accession>
    <name>A0A518IY50_9BACT</name>
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        <submittedName>
            <fullName evidence="6">Planctomycete cytochrome C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Mal33_40360</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="6 7">Mal33</strain>
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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        <property type="entry name" value="DUF1549"/>
    </dbReference>
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        <property type="entry name" value="DUF1553"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
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            <begin position="26"/>
            <end position="125"/>
        </location>
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        <source>
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        </source>
    </evidence>
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        <source>
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    </evidence>
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    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="QDV58020.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="876" mass="98614" checksum="81A03F5FAABABB40" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
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    <name>A0A518IY78_9BACT</name>
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        <submittedName>
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        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">Mal33_40600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="146"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="193"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="253"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="281"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="358"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="396"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="430"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="748" mass="84579" checksum="8AC976B0CECAE716" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYD1</accession>
    <name>A0A518IYD1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Acyl-CoA dehydrogenase</fullName>
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        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">mmgC</name>
        <name evidence="10" type="ORF">Mal33_41010</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the acyl-CoA dehydrogenase family.</text>
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    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003995">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
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    <dbReference type="InterPro" id="IPR046373">
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    </dbReference>
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        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
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        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
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        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
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        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00072">
        <property type="entry name" value="ACYL_COA_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="3 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA_dh_N" evidence="9">
        <location>
            <begin position="135"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_M" evidence="8">
        <location>
            <begin position="245"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="7">
        <location>
            <begin position="350"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="26"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="27"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV58084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="684" mass="75243" checksum="49F0AB5F12F9D299" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYK0</accession>
    <name>A0A518IYK0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_41900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="SSF53633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="207" mass="23135" checksum="854A7E2494432795" modified="2019-10-16" version="1">MTDKRPAMRVVKLGGSLLINPDLAVAVRRWLTAQTQRKTAIIVGGGELVDVMRAMDRRFELDLVAMHWRCIRLLRHTFEIVSELMPELVPIGDAKALERWSHDRGDRSAALVAVDAFYDSQARGPISLPTNWATTTDSIAALLARQLEATELVLLKSCSVAETIDWQEAARREIVDAAFPQFIEGIPDVRLVNLKDHLPGTTLQQED</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYK5</accession>
    <name>A0A518IYK5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Thiol-disulfide oxidoreductase YkuV</fullName>
            <ecNumber evidence="3">1.8.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ykuV</name>
        <name evidence="3" type="ORF">Mal33_41840</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.8.-.-" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016209">
        <property type="term" value="F:antioxidant activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021760849" evidence="1">
        <location>
            <begin position="21"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="2">
        <location>
            <begin position="208"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="361" mass="41061" checksum="5EE13AB72D0147CA" modified="2019-10-16" version="1" precursor="true">MKSLFAIAIVAVAAATAARADDSPTAAADDLVPRYFLAMVHAPEVHAELELSEAQIADLENVFQSVDSTWFQSRLLPADQQNKIIDQTELPVRKWFADNTSAKQQQRLKQLECYSQGVRMLLTDEMATQLDIDRGQQTKLIALAKTCRDLEQRLQKAVAAKQPTDDLTEKLQKAVAAEREGYKLVLKPQQIQKLGQVLGEPFDTGQLKRTYPMAPEFVAVEHWLNSPPLQIRELKGKVVLVHFYAFQCHNCHANFAHYQRWHRELRDKGVVVVGIQTPETSRERDPKAVRAAAVDRQLEFPILVDLGSQNWRAWGNTMWPTVYVVDKQGYIRHWWQGELNWQGATGDKTIEDLVEQLLQEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYK8</accession>
    <name>A0A518IYK8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_41810</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011486">
        <property type="entry name" value="BBP2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07642">
        <property type="entry name" value="BBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022044782" evidence="1">
        <location>
            <begin position="25"/>
            <end position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="470" mass="51257" checksum="C70E53B84AC430A8" modified="2019-10-16" version="1" precursor="true">MRKNILGALSIALAIATHQNVLLAGSPSCLSSLRCDDGMLCDSAAHYRGGSDCDARMICGDECNDGCLGGCSDLCGAGCDHGGFGCDAGMDSCCDGGLFGLGLLGQASSGWNVSGWVDAGFIGNTSSPNSKFNGPYNAVDRSNEGMLNQLYMIVEKRLPRYGAGIGGRVDILYGEDYLLAQSNGLERRDDGAARWNGEYYGLALPQAYVSMGNEDVSLQVGHFYSVVGYEGVMAPDNFFYSKSYSYQFAGPFTHWGAQLNVRPTDALSFNLGIHNGWDSLDRESDKPGFIGKVRYDSQSSKAWTSFAITTGDSSNDLAGVALNPDFTNRTRYSWLVALPVTKRLDYVFHHWLGFQEEGAPDGGRADWYGIDQYLTYCFTDRLKGAVRFEWFRDEEGTRVGLNRPSNPNNPPFVGDFYSLSAGFNMAVSKNLTIRPELRADWFDGTAASQPFDDGNDDNQFMLGIDAIFRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYL5</accession>
    <name>A0A518IYL5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acyl-CoA thioester hydrolase YbgC</fullName>
            <ecNumber evidence="3">3.1.2.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ybgC</name>
        <name evidence="3" type="ORF">Mal33_41970</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.2.-" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006684">
        <property type="entry name" value="YbgC/YbaW"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003230">
        <property type="entry name" value="YbgC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00051">
        <property type="entry name" value="TIGR00051"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4HBT" evidence="2">
        <location>
            <begin position="19"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="132" mass="15381" checksum="B973D3986FC529E9" modified="2019-10-16" version="1">MSQQHTLTIRVNYHETDGQGRVHHANYLNYFERGRVELLRSLGSSYKQFEADGRMLVVAEMNVKYHQMAEFDDELTLTTTVLEAHGARIRHRYEIFRDDQLLVFAESVIACVRSDGRATRLPAELQQGRRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYM3</accession>
    <name>A0A518IYM3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_42100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="72" mass="7904" checksum="70110A18BE851D66" modified="2019-10-16" version="1">MLDADDSDYLVTGSAGQKRPWERELGSSAVAVAAILYTKSGFQTYPLNIGHKLGVSDFRAHLIDSDDEHHTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYN5</accession>
    <name>A0A518IYN5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">MMPL family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Mal33_42180</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004869">
        <property type="entry name" value="MMPL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000731">
        <property type="entry name" value="SSD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03176">
        <property type="entry name" value="MMPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50156">
        <property type="entry name" value="SSD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="430"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="456"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="482"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="526"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="556"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="620"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="990"/>
            <end position="1014"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="1026"/>
            <end position="1052"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="1106"/>
            <end position="1129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="1135"/>
            <end position="1159"/>
        </location>
    </feature>
    <feature type="domain" description="SSD" evidence="8">
        <location>
            <begin position="463"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="domain" description="SSD" evidence="8">
        <location>
            <begin position="1033"/>
            <end position="1160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1177"/>
            <end position="1234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1217"/>
            <end position="1234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV58201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1234" mass="134645" checksum="1D977EB3D09C37C2" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYR5</accession>
    <name>A0A518IYR5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Succinate-semialdehyde dehydrogenase [NADP(+)]</fullName>
            <ecNumber evidence="3">1.2.1.79</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">gabD_2</name>
        <name evidence="3" type="ORF">Mal33_42530</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.2.1.79" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036243">
        <property type="term" value="F:succinate-semialdehyde dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="2">
        <location>
            <begin position="6"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="490" mass="52693" checksum="95A5530BD495FE4C" modified="2019-10-16" version="1">MTLVDGSNCRAALDNAAAAQKQWARLSVRQRGLRMHAVQTRIAQVADDLCDLITLPQRRSKTETLSAELIPLCEALRYLQRDAAKVLATRKLPLSGRPLWLWGTRAEVQRVALGRVLIIAPWNYPLFLAGVQAAQALVAGNAVLLKPAPGCEAATATLVDCFQAAVGTDLIRQVGSDPEVATRLIQAGVEKVVLTGSSTTGRRVGSVAADALTPATMELSGCDAMVVLPEADRGRVVESLLFGLSFNSGATCIAPRRIFLCQRQSDHYRKLLKQRLVQMPSIPVHPAVQTRMIEAVEDAIARGARVVGGLWDREAFERTGATPPLVLFGAQPDWPIMSADLFAPLAAVCDYASPDELADLVARAPYALAASIFGPQKEARQLADLLDVGTVTINDLIVPTADPRIPFGGRRASGFGTTRGAEGLLAMTCPRVIATQRLRHPKHLAAPTAGDEAILAGLLQLKFAAGWRLRLRGLGQMVRGIRQSRNNDSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYZ1</accession>
    <name>A0A518IYZ1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF2384 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_43190</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024467">
        <property type="entry name" value="Xre/MbcA/ParS-like_toxin-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09722">
        <property type="entry name" value="DUF2384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2384" evidence="1">
        <location>
            <begin position="84"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="132" mass="14712" checksum="5DB5534142F48EE7" modified="2019-10-16" version="1">MTKKTPNNHSTATSRTGGLAIVEDTRGRRALQLRSKLGMSREVFARLVPTSVRNLASLESGQPPSPVIQKNLTELQRVISALEDVVKQEAIGPWMDQPNAAFEGLKPIEVIERGEIDRIWRMLYQLQSGDAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYZ8</accession>
    <name>A0A518IYZ8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glutamate 5-kinase</fullName>
            <ecNumber evidence="8">2.7.2.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Gamma-glutamyl kinase</fullName>
            <shortName evidence="8">GK</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 10" type="primary">proB</name>
        <name evidence="10" type="ORF">Mal33_43320</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>ATP + L-glutamate = ADP + L-glutamyl 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:14877"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58274"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.11"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-glutamate: step 1/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the glutamate 5-kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.11" evidence="8"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00098">
        <property type="reaction ID" value="UER00359"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004349">
        <property type="term" value="F:glutamate 5-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055129">
        <property type="term" value="P:L-proline biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04242">
        <property type="entry name" value="AAK_G5K_ProB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00456">
        <property type="entry name" value="ProB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041739">
        <property type="entry name" value="G5K_ProB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001057">
        <property type="entry name" value="Glu/AcGlu_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011529">
        <property type="entry name" value="Glu_5kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005715">
        <property type="entry name" value="Glu_5kinase/COase_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019797">
        <property type="entry name" value="Glutamate_5-kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002478">
        <property type="entry name" value="PUA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036974">
        <property type="entry name" value="PUA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01472">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000729">
        <property type="entry name" value="GK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00474">
        <property type="entry name" value="GLU5KINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00359">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="SSF53633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="SSF88697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01027">
        <property type="entry name" value="proB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00902">
        <property type="entry name" value="GLUTAMATE_5_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 8" id="KW-0641">Proline biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PUA" evidence="9">
        <location>
            <begin position="288"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="20"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="181"/>
            <end position="182"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV58314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="386" mass="40964" checksum="CDCF342914218CAE" modified="2019-10-16" version="1">MSTDINRIEALAAAETLVVKVGTRVLTSPDGCLDRERIAILAEQLCKVMDTGRTVVLVSSGAVGAGIGKLGLTERPRMLADLQAVAAIGQTDLMQAYQHAFAQHGRHAAQVLLTAEDLRNRSSFLNLRNALRQIAAYKAVPIINENDSVAVEELMTTFGDNDRLAASVASLINDAMLVILTDIDGLHTCHPSDPNSKRMSTVETINHEVIAMACDTQNSVSKGGMSSKLVAAQIATSHGHSVIIGPGRDDRVLEKILAGESIGTLFQPEEKAIRGRLRWIDSAAALAGELHVDAGAARAVGDRGKSLLAIGIRRVEGVFDRGEVVAIIDPQGAEIARGLINYTSEEATKIIGLPSGQIADVLGHCPYDTVIHCDNIATNSGLPLPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ68</accession>
    <name>A0A518IZ68_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Bacterial type II secretion system protein F domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Mal33_43970</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.81.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018076">
        <property type="entry name" value="T2SS_GspF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042094">
        <property type="entry name" value="T2SS_GspF_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00482">
        <property type="entry name" value="T2SSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="96"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="266"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="299"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="domain" description="T2SSF" evidence="7">
        <location>
            <begin position="155"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV58379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="322" mass="34872" checksum="65B4266E150F51ED" modified="2019-10-16" version="1">MITLIIVIAVGVGIAALIAGAWLMVDSEAGGPSTAENRLDTLARLKKDVDDPSQSTALYAGGFDESKDRLDALLKSLPGMGLYLEQADLSLNAGKFFALVGGLFAAGIGLCFVTPIPVLLGPILGGMLASIPFLYVMFMRNRRLAKFGNQMPEALELLSRSLRAGHSLAAGFGLIASEMRDPIRKEFARCFEEQNLGIALEEALDDMTGRVPNMDLKFFAMAIILQRETGGDLAEILDKISHLVRERLQIQGQVAALTGEGRMSGIVLLAMPPTLFLTMLYLNYDYAMMLFTDPMGRKMMAGALVMQLLGAVVIRKIITIRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZF8</accession>
    <name>A0A518IZF8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_45010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022100413" evidence="1">
        <location>
            <begin position="32"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="487" mass="53493" checksum="DBD6EF03D3430735" modified="2019-10-16" version="1" precursor="true">MLLLVSQLQRPLVMLAATASILLATASPLLAAELHIGGASVSITPEQPVALTGQMRTRISANVESEVTATALALESRDGDNVVDQAIMVSCDLIAIREGLLDAVRQRLQDQIPDFDPSKLVMNATHTHTAPVLREGIYQLPDEGIMRPSEYVEFLADRVAGAAATAWKARQPGQVGWGLGHAVVAQNRRTVYSNGTAAMYGATAKDNFLEIEGYEDHGVEVLFFWDAKDQLIATCVNVACPAQEVEGRSAVNADFWHPVRNTLREKYGEDLHVLAWTGAAGDQSPHLMYSKPAEERMRKLRGLTRLEELSRRIVVAWEEALQGASQERHSDVPFVHSVKTIELPERMVTHEESFAIKAKVAELATDPKQKRRMQWHQAAVDRFDRQQAGELQPYEMELHAIRLGDIAIATNDFELFTDFGIQMKARSPALQTFVIQLAGPGTYVPSARAARGSGYSAIVESNLVGPEGGQALADQTVEQLKSLWSDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZI4</accession>
    <name>A0A518IZI4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD dependent epimerase/dehydratase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_44680</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="8"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="351" mass="39213" checksum="8E01A78044FE23E8" modified="2019-10-16" version="1">MSERRPAVIVTGSSGLLGRPVCTQLAQLGYEVYGFDRVGLPEPPKRHPHVHDVECDISSYENVRGAVDDVRRRCDAKLASVVHMAAFYDFSGEPSPLYEEITVNGTDRLLNALSDFELEQFVFTSTMLVHQPCSPGERIAEDDPLQAKWPYPESKIATERLIREGHPGVRSVMLRIAGVYTDYGRQPTIVQQIKRIYESDFQSHFFPGDTAAGQAAVHCDDAIAAIVATVQKRSDIEPKTAILIGEPEPPSYETLQDAIGQRLHGKDWKTLYVPPALAKVGASVTDTLSGGEAFIKPFMVDMADDHYALDISRAKQLLDWEPRHRLIDSIPKMLDALQDDPDRWYRQNGLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZI5</accession>
    <name>A0A518IZI5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Endo/exonuclease/phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_45220</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="SSF56219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endo/exonuclease/phosphatase" evidence="1">
        <location>
            <begin position="7"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="241" mass="27339" checksum="39DF74C98D194936" modified="2019-10-16" version="1">MQFRLTTYNIHKGIGGVDRRYDPDRIVQAVGHCNPDILFLQEVDDGVPRSRHDRQVEVLGEALGLKHHVYQRNVKLKVGHYGNAILSRFPLTDHQDIDLTIPMKKKRRALAAHCRMQIDGHSRTVLLLNVHLGLAGFERKMQLRRLLATELVRRTHQETAVLLAGDFNDVWGNLGRGILDTGGFQSATGLHKTFPAFMPMRPLDRVYFRGNMSIDHGFASRTDIARRASDHLPLVADCILQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZP6</accession>
    <name>A0A518IZP6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 12">Adenine DNA glycosylase</fullName>
            <ecNumber evidence="3 12">3.2.2.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">mutY</name>
        <name evidence="14" type="ORF">Mal33_45900</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Adenine glycosylase active on G-A mispairs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolyzes free adenine bases from 7,8-dihydro-8-oxoguanine:adenine mismatched double-stranded DNA, leaving an apurinic site.</text>
            <dbReference type="EC" id="3.2.2.31"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="12">Binds 1 [4Fe-4S] cluster.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the Nth/MutY family.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.31" evidence="3 12"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000701">
        <property type="term" value="F:purine-specific mismatch base pair DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03431">
        <property type="entry name" value="DNA_Glycosylase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00056">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1670.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005760">
        <property type="entry name" value="A/G_AdeGlyc_MutY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003265">
        <property type="entry name" value="HhH-GPD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023170">
        <property type="entry name" value="HhH_base_excis_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000445">
        <property type="entry name" value="HhH_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044298">
        <property type="entry name" value="MIG/MutY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029119">
        <property type="entry name" value="MutY_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42944">
        <property type="entry name" value="PTHR42944"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00633">
        <property type="entry name" value="HHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00730">
        <property type="entry name" value="HhH-GPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14815">
        <property type="entry name" value="NUDIX_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00478">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="SSF48150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01084">
        <property type="entry name" value="mutY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6 12" id="KW-0227">DNA damage</keyword>
    <keyword evidence="10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="11 12 14" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 12" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ENDO3c" evidence="13">
        <location>
            <begin position="55"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU365096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="QDV58567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="367" mass="41768" checksum="A834E55AF91016DC" modified="2019-10-16" version="1">MSSAAESIDHDPRWRDSAWRSRLRRRLLQWFETNSRTLPWRQSRDPYRVWISEIMLQQTQVATVIPYFERFTESFPTVAELAAASEQEVLRHWEGLGYYRRARQMHAAAQKIVEEHDGEFPEVFADVLALPGIGRYTAGAILSISRDQRLPVVEANTLRLYSRLIGLRSPPTIAASQRVLWEFAESILPQRGSGHLNQAAMELGSLVCTPRAPTCTHCPLANGCVAREMGLQETIPGKVKKIQYEDRREVAVVVRDDKRFLVRQCQPGERWAGLWDFPRCEIAGDADASLVAADHLRDAFNQTIEPPQPLMRIKHAVTKYRITLEVLSAKLLDEPQPIDAPGTRWLTRGQIGKLPLSTTGRKIFLKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZR5</accession>
    <name>A0A518IZR5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">p-hydroxybenzoic acid efflux pump subunit AaeB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">aaeB</name>
        <name evidence="2" type="ORF">Mal33_45480</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="PHBA_efflux_AaeB/fusaric-R"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04632">
        <property type="entry name" value="FUSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="117"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="146"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="392"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="436"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="464"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="513"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="544" mass="61108" checksum="AAA7BDC26CD78B76" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZS6</accession>
    <name>A0A518IZS6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF5077 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_46140</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="entry name" value="DUF3472"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031712">
        <property type="entry name" value="DUF5077"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11958">
        <property type="entry name" value="DUF3472"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16871">
        <property type="entry name" value="DUF5077"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022061658" description="DUF5077 domain-containing protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="domain" description="DUF5077" evidence="2">
        <location>
            <begin position="41"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="437" mass="47986" checksum="636B507B455AF8F8" modified="2019-10-16" version="1" precursor="true">MTNYFASLFRPLGLAARVAFAGVVISIATAAVGADWTVPLAGNAYRAPVDRGGRLFSPDGALRVSEGDATDSVYFHVDRPGVISLALRARAVDGDAAIEARVGDQRLATKVRGAEENEYPLGEVSVAAAGYVRVDLQASGGKAEVSQLVVQSDVDGMTLDYVKNNEGDMYYWGRRGPSVHLQYQTPTKIDLTYAYSEITVPEGQDVLGAYYMANGFGEGYFGIQVNSPRQRRVLFSVWSPFRTDNPKEIPADQRVVTLAKGEGVKAKDFGNEGSGGQSYLVYPWTAGTTYRFLTEVKPDGNGNTIYTSWFGDKAEGRWRLIASFRRPKTDRHLTGFHSFLENFIPDFGALPRTANYGNQWVCDVDGSWHEVTRARLTGDNTARGRHRLDYAGGAVGDHFFMKHCGFFSPHVALDQTFQRESDAGSKPAIEFDRLPRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZT3</accession>
    <name>A0A518IZT3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_46240</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025711">
        <property type="entry name" value="PepSY"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13670">
        <property type="entry name" value="PepSY_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PepSY" evidence="1">
        <location>
            <begin position="24"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="domain" description="PepSY" evidence="1">
        <location>
            <begin position="89"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="154" mass="17576" checksum="7D584E4C75B76AFA" modified="2019-10-16" version="1">MKALILCAIPGILALIPIQFTDAQSTGGSRMPLIEIVRQLEADGYKPFSEISMDDGNWEVEVRQNDVAYELTVDSFTGKILSQHRDDPDDHPAKDSLPLSEVLKSLAERDGYSDIDEVSFERRYWEVEAFRNRQKRELHVDPRTAKIIADRIDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J007</accession>
    <name>A0A518J007_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">barA_12</name>
        <name evidence="10" type="ORF">Mal33_46860</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
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        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
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    </evidence>
    <sequence length="618" mass="70368" checksum="9BC6D9EF9523F7F7" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
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    <name>A0A518J079_9BACT</name>
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        <submittedName>
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
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                <person name="Kallscheuer N."/>
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                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
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                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
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                <person name="Bruemmer F."/>
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                <person name="Devos D.P."/>
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                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 4">Mal33</strain>
        </source>
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        </location>
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        <source>
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    </evidence>
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    </evidence>
    <sequence length="368" mass="41657" checksum="409656DEFEFF0845" modified="2019-10-16" version="1">MRIAQVAPLIETVPPKTYGGTERVVHYLTEELVRQGHDVTLFASGDSRTEADHVAVVKESLRCSRETRDPVVWHQRQLMEVLRMADKFDIIHFHTDFSHFSAMRYLNTPHVTTLHGRLDLPDFQTVFDEFPDMPVVSISDSQRRPIPHANWVGTVYNGTPGENYMFQPTPDPVEYFAFLGRFSPEKGPERAIEIAKRLGVKLKMAAKIDRVDEQYFAERIQPHLSDPLIEYIGEVDEEGKNELLGGAKALLFPIDWPEPFGLVMTEAMACGTPVVAFRNGSVDEVMKPGVTGYIVESIDEAVAAAENIDKISRRGCRLYFQDRFDVEPMTHGYVQVYEKLIAPQPTIRIPSRRAIAKSNDQPLTMETA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0D8</accession>
    <name>A0A518J0D8_9BACT</name>
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Pinto D."/>
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                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
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                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
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        <property type="entry name" value="Transptr-assoc_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03471">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01091">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="64"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
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        </location>
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    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
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        </location>
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    <feature type="domain" description="CBS" evidence="5">
        <location>
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        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="5">
        <location>
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        </location>
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    <evidence type="ECO:0000256" key="1">
        <source>
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        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="QDV58792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="432" mass="48258" checksum="22333DA389004EB1" modified="2019-10-16" version="1">MLDLQLVVVIAITGFAMGTTGGLGAELLERFIGRSLEAYCRLQGRRGRFGEVLDRQEDATRGALYLRIIGNVLFLSCGTIAVIAPSVSENGVDGSRLLTWLAIASGLVMFTHLWLPAAVTRFASAPVLYRTWPFWNGLAVVMHPLSIPGVLVEWFARRLSGQQEDASEEEELLEDEIRTIITAGTRDGHFGPGVREMIQGVMDMHDDSVSHIMTPRSDVDAIEIDTPWPEILKVVVESGRTRLPVYRDNLDNVVGVLYVKDLLSELSILKDPNVPLEKLLRRTWTVPASKRVDELLQEFLHSRSHMAIVLDERHQFSGVVTIEDSLEEIVGEIVDESDDEEQTDFHIVDAQTADMSGRIMVDEVNERLGWELAESDDYETIAGYVLHHAGYMPRQDEAIELGPLEIKVLRATSRQLERLRLRHIGSSALEAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0H1</accession>
    <name>A0A518J0H1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Planctomycete cytochrome C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_48660</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011429">
        <property type="entry name" value="Cyt_c_Planctomycete-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011444">
        <property type="entry name" value="DUF1549"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022655">
        <property type="entry name" value="DUF1553"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07635">
        <property type="entry name" value="PSCyt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07583">
        <property type="entry name" value="PSCyt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07587">
        <property type="entry name" value="PSD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021838210" evidence="1">
        <location>
            <begin position="29"/>
            <end position="1012"/>
        </location>
    </feature>
    <feature type="domain" description="PSCyt1" evidence="4">
        <location>
            <begin position="52"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="PSCyt2" evidence="2">
        <location>
            <begin position="178"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="domain" description="PSD1" evidence="3">
        <location>
            <begin position="721"/>
            <end position="979"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV58841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1012" mass="113561" checksum="C939CA8D4374592E" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0V0</accession>
    <name>A0A518J0V0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sialidase</fullName>
            <ecNumber evidence="3">3.2.1.18</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">nedA_3</name>
        <name evidence="3" type="ORF">Mal33_49980</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.2.1.18" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052794">
        <property type="term" value="F:exo-alpha-(2-&gt;3)-sialidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052795">
        <property type="term" value="F:exo-alpha-(2-&gt;6)-sialidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052796">
        <property type="term" value="F:exo-alpha-(2-&gt;8)-sialidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008152">
        <property type="term" value="P:metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011040">
        <property type="entry name" value="Sialidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026856">
        <property type="entry name" value="Sialidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036278">
        <property type="entry name" value="Sialidase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10628">
        <property type="entry name" value="PTHR10628"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13088">
        <property type="entry name" value="BNR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50939">
        <property type="entry name" value="SSF50939"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021893824" evidence="1">
        <location>
            <begin position="23"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="domain" description="Sialidase" evidence="2">
        <location>
            <begin position="105"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="371" mass="41314" checksum="A787473E8BDEC81F" modified="2019-10-16" version="1" precursor="true">MNVRTLLFLLLACSSFGTHLLAQSPQTVMTLPTGPDNPRNTEGGFVTLKDGRILYIYSRFLGESGGDNAHGYLTACTSDDGGKTWTNHDEPIFPREGKENDMSASLLRLADGRIALFYLVKHSIMDCRLRMRTSSDEAKTWSDPVDCMPGETNYFVVNNDRVIQTRSGRLIAPAAVHVRDGKWTRESDIACYLSDDAGKTWRRGKQTFHGINEAGTRYLTQEPGVVELKDGRILLWCRANIGTQAYAYSEDGGETFSPMKAWNFSSPVSPASIKRIPSTGDLLLVWNEGTGRRTPLNAAISSDDGATWTHNAAIETDPKGWFCYTAIHFVDDRVLLAYWLTEQLKRPLKIGTKIVSVPVEWFYQNDAGVSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0Z9</accession>
    <name>A0A518J0Z9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">IS1 transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_50390</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="318" mass="36015" checksum="DFCB2EDD5DF32AF3" modified="2019-10-16" version="1">MIAPCEHENRKKHGTDRYGNQRFRCKDCGQTFQEYRVRPIGTMQIDLDRACMALSMLLEGMSIRATARITNIDQNTIGNLILTAGEQCGRLLDSISGISVTDIQIDEIWTFVGMKQRTANLRNLGDDSSVGDNWTYIAVERYTKMVLAHHVGRRDTNDTNVFLGKVRRAIDASLPFQVSTDGLSNYRYGVPFALGSNANFGMLIKKYAAQQQETRYSPAAIIGTEKKAVFGSPDPDSICTSHIETLNQKIRMHLRRFTRLTAGHSKSVEHHVAMQNIFFAWYNWCRKHHTLRQTPAMECGIAMTKWSIRELLESSATC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J135</accession>
    <name>A0A518J135_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_50780</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="54" mass="5850" checksum="1765947448E16BF3" modified="2019-10-16" version="1">MKLLQNFAHTNLASPSGPKVHSNHAVAMLASDQNCLQGHHRSGKTLKTTTAKNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1A3</accession>
    <name>A0A518J1A3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Arylsulfatase</fullName>
            <ecNumber evidence="4">3.1.6.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_51450</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="PTM">
        <text evidence="1">The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.</text>
    </comment>
    <dbReference type="EC" id="3.1.6.1" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004065">
        <property type="term" value="F:arylsulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022209854" evidence="2">
        <location>
            <begin position="26"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase" evidence="3">
        <location>
            <begin position="32"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="modified residue" description="3-oxoalanine (Cys)" evidence="1">
        <location>
            <position position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR600917-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV59119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="499" mass="55384" checksum="C675232BBE8C8D59" modified="2019-10-16" version="1" precursor="true">MKSNSTLLVATLFLFAMFSGVNLNAADPNVPPNIVWIIPDDMSAEFSCYGETAIETPNVDSLATAGVKFTNAYVTAPVCSTCRSAFITGMYQTSIGAHHHRSGRGTKKIELPDGVAMVPKLFQEAGYHTSITGWPMNGKLGKTDYNFQWDKSIYDSNDWGDRKPGQPFFAQIQTQGGKLRGKDARGWEKIATAAEKQLGSRTPISAVALPPYYPNHPDIVRDWAAYLDSVRMTDAMVGEVVARLESEGVRDNTLILFMTDHGISHARGKQFLYDEGLHLPLVIAGPGIAAGTVREDLVEHIDIAALSLAAAGIPIPANMQARDILAADYQPRTAVLAARDRCDETVEHIRSVRTEDFKYIRNFLPNRPYLQPCAYKDAKQILIALRQWHAAGKLNATQELLFRETRPPEELYDLKSDTHEIDNLADDPAFAQQLKSLRGQLDQWMETTGDQGRQPESAAMYDSDMAVYLDSVQRRGTAEYLKTLQENIALMKRWAAEGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1K9</accession>
    <name>A0A518J1K9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Penicillin acylase</fullName>
            <ecNumber evidence="5">3.5.1.11</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_52400</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C59 family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.11" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008953">
        <property type="term" value="F:penicillin amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029132">
        <property type="entry name" value="CBAH/NAAA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02275">
        <property type="entry name" value="CBAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021778221" evidence="3">
        <location>
            <begin position="24"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="domain" description="CBAH" evidence="4">
        <location>
            <begin position="24"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV59212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="346" mass="38047" checksum="64263D43B7B20104" modified="2019-10-16" version="1" precursor="true">MNGIYLTCLSILALAMAAGTVQACTRVLWNNNKLAVVVSRTMDWPTTTEPILTLLPRGLQHDGGKIGPEVLVKENPARWTSKYGSLVTTVYGIGTADGFNEKGLGVHMLYLTATNFGERDENKPAVHAGLWGQYLLDNAASVKEALQLQEAIQIVMVEAKGRMATVHLAIEDASGDSAILEFIDGKLVVHHGRQFQVMTNDPTYDQQLELLDKLDFSNPSSETPLPGNVKPTDRFQRASYYTALLPEPKDERQAVAGVLAIARNVSVPFGAPYKGFGIYNTEYRTVMNLTKLRYFFELTTSPNVIWADLLKFDLNPGAPVKVLDPDNIDLSGDVSSQFKTLETPPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1N2</accession>
    <name>A0A518J1N2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">DNA ligase</fullName>
            <ecNumber evidence="8">6.5.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Polydeoxyribonucleotide synthase [NAD(+)]</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ligA_2</name>
        <name evidence="8" type="synonym">ligA</name>
        <name evidence="10" type="ORF">Mal33_52680</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="8">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the NAD-dependent DNA ligase family. LigA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.5.1.2" evidence="8"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003911">
        <property type="term" value="F:DNA ligase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01588">
        <property type="entry name" value="DNA_ligase_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041663">
        <property type="entry name" value="DisA/LigA_HHH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001679">
        <property type="entry name" value="DNAligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013839">
        <property type="entry name" value="DNAligase_adenylation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013840">
        <property type="entry name" value="DNAligase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004150">
        <property type="entry name" value="NAD_DNA_ligase_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00533">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01653">
        <property type="entry name" value="DNA_ligase_aden"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03120">
        <property type="entry name" value="DNA_ligase_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12826">
        <property type="entry name" value="HHH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001604">
        <property type="entry name" value="LigA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00292">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00532">
        <property type="entry name" value="LIGANc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="SSF47781"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="SSF52113"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7 8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="2 8" id="KW-0235">DNA replication</keyword>
    <keyword evidence="1 8 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0464">Manganese</keyword>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 8" id="KW-0520">NAD</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="BRCT" evidence="9">
        <location>
            <begin position="637"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="active site" description="N6-AMP-lysine intermediate" evidence="8">
        <location>
            <position position="155"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="42"/>
            <end position="46"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="85"/>
            <end position="86"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="211"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="351"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="440"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="443"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="462"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="467"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV59240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="720" mass="78715" checksum="0E7677FEE61193EA" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1Q7</accession>
    <name>A0A518J1Q7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Conjugal transfer protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_53020</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GSP E family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001482">
        <property type="entry name" value="T2SS/T4SS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00437">
        <property type="entry name" value="T2SSE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T2SP_E" evidence="2">
        <location>
            <begin position="121"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV59274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="467" mass="52239" checksum="DCBEC12028EF0183" modified="2019-10-16" version="1">MNDRRTLRERLQRKSIEVPKDRLRRNVEESLQNDSKAATPRRVNRNIEYQAIKGDLHERLIDELNRQGALTRSDAELRPLIEAFVADVLTREDWPLNATERDRLASDLLEETLGTGPLAPLMADPAVTDILVNRFDSVYVERFGVLEETDVRFRDDEHLVRIIGRIASRVGRRVDTSSPMVDARLPDGSRVNATLPPVTIDGPTLSIRRFGRRRLTRQDLVRLGMFSPAMDRFLEVLVRHRKSVIVTGGTGSGKSTLLGAIAEAIPDNERIITIEDAAELMLSQTHVIRMETRAPNTEGKGTIAQRDLVVNALRMRPDRIVMGEVRAGEALDMLQAMNTGHDGSLTTIHANSPRDAFARLETMVMMSGMELPSQAIREQAVSAVDYIVHVRRYEDGGRRVAQISEVVGIEGKTPQLQDVFVFQPTGRSEGRLTGTFQATGVVPRIVDELASRGIHEIDRGWFGSPAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1X2</accession>
    <name>A0A518J1X2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tetratricopeptide repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_53670</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="22"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="55"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV59339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="489" mass="54655" checksum="64E0970BCD0D795E" modified="2019-10-16" version="1">MMTDLFSALRAFTSDWFTTRNYVSLLAGVPALLGVACVGLIVGMSAPKSVQLKRYDQYQRAGVAAMQVDDYARAKLWFERALQIRPDEPRVQLALAEATHHDGEPEVAIKILQDVIAKGDRGTAAKAALLAVKIRINALPDAENDAQRGALLQSSEAFARIALEKAPESRDAAGALAQILAQTGRVDVAIETLEPIATQHRDFYVTLAHLAAANRDPGSAKRYAENAVQFLKPQIAIQPNNFNVRSALANMLQQTGDFNEATRLLNDGMRLANDEQKELLSEVYVGIALREFDRLSDETYSLQILQKQLALLDQMLKFRPDNLKVMARLARMVGAYEFLDEKYEAHLKQSLTETPYPETIHLILGTYYAKAEQFDEALFHLEAAYRSELKSATLMNNLAWVIIATQPQEADRALTLVEAAIKLRPTDPDLISTRAEILFKQQRWDAARNDFESILGRVENQKQVHERLAVIYDKLGKGDIAELHRSKSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1Y0</accession>
    <name>A0A518J1Y0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Valine--tRNA ligase</fullName>
            <ecNumber evidence="8">6.1.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Valyl-tRNA synthetase</fullName>
            <shortName evidence="8">ValRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 13" type="primary">valS</name>
        <name evidence="13" type="ORF">Mal33_53720</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + L-valine + tRNA(Val) = AMP + diphosphate + L-valyl-tRNA(Val)</text>
            <dbReference type="Rhea" id="RHEA:10704"/>
            <dbReference type="Rhea" id="RHEA-COMP:9672"/>
            <dbReference type="Rhea" id="RHEA-COMP:9708"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57762"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78537"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.9"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="8">The C-terminal coiled-coil domain is crucial for aminoacylation activity.</text>
    </comment>
    <comment type="domain">
        <text evidence="8">ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.9" evidence="8"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA editing activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004832">
        <property type="term" value="F:valine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006438">
        <property type="term" value="P:valyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07962">
        <property type="entry name" value="Anticodon_Ia_Val"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.740.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02004">
        <property type="entry name" value="Val_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033705">
        <property type="entry name" value="Anticodon_Ia_Val"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010978">
        <property type="entry name" value="tRNA-bd_arm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037118">
        <property type="entry name" value="Val-tRNA_synth_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019499">
        <property type="entry name" value="Val-tRNA_synth_tRNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002303">
        <property type="entry name" value="Valyl-tRNA_ligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11946">
        <property type="entry name" value="PTHR11946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10458">
        <property type="entry name" value="Val_tRNA-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00986">
        <property type="entry name" value="TRNASYNTHVAL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46589">
        <property type="entry name" value="SSF46589"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="SSF50677"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 8 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA-synt_1" evidence="10">
        <location>
            <begin position="18"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="domain" description="Anticodon_1" evidence="11">
        <location>
            <begin position="742"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="domain" description="Val_tRNA-synt_C" evidence="12">
        <location>
            <begin position="958"/>
            <end position="1023"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="998"/>
            <end position="1025"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="8">
        <location>
            <begin position="46"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="611"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF10458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="QDV59344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1027" mass="115788" checksum="9C1D95E9A9F48DCC" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J281</accession>
    <name>A0A518J281_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 10">Phosphoenolpyruvate carboxylase</fullName>
            <shortName evidence="10">PEPC</shortName>
            <shortName evidence="10">PEPCase</shortName>
            <ecNumber evidence="5 10">4.1.1.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10 13" type="primary">ppc</name>
        <name evidence="13" type="ORF">Mal33_54740</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 10">Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>oxaloacetate + phosphate = hydrogencarbonate + phosphoenolpyruvate</text>
            <dbReference type="Rhea" id="RHEA:28370"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="4.1.1.31"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the PEPCase type 1 family.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.31" evidence="5 10"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008964">
        <property type="term" value="F:phosphoenolpyruvate carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015977">
        <property type="term" value="P:carbon fixation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006107">
        <property type="term" value="P:oxaloacetate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00595">
        <property type="entry name" value="PEPcase_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021135">
        <property type="entry name" value="PEP_COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022805">
        <property type="entry name" value="PEP_COase_bac/pln-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018129">
        <property type="entry name" value="PEP_COase_Lys_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033129">
        <property type="entry name" value="PEPCASE_His_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30523">
        <property type="entry name" value="PTHR30523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00311">
        <property type="entry name" value="PEPcase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00150">
        <property type="entry name" value="PEPCARBXLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00781">
        <property type="entry name" value="PEPCASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00393">
        <property type="entry name" value="PEPCASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0120">Carbon dioxide fixation</keyword>
    <keyword evidence="8 10 13" id="KW-0456">Lyase</keyword>
    <keyword evidence="7 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="13" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="10 11">
        <location>
            <position position="148"/>
        </location>
    </feature>
    <feature type="active site" evidence="10 12">
        <location>
            <position position="577"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="QDV59439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="912" mass="102612" checksum="0A5F290B9DEDD581" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J285</accession>
    <name>A0A518J285_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator SlyA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">slyA_2</name>
        <name evidence="2" type="ORF">Mal33_54850</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01047">
        <property type="entry name" value="MarR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="3"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="153" mass="17019" checksum="FDD2D2C00AE5DA33" modified="2019-10-16" version="1">MTESSLSDTLHRLMHAYKRQLRAGIETQQISLPITQLRVLKCIGRIPECTARSIAQRMNQDKGQLARLLNELTDVALIDKMANPQDRRSHFLVLTSAGKQILAKLEVVEKQAAGQMTRGLSSKEIKTFIRIAAAMMENSDDGGTSKRGTQRDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ILZ1</accession>
    <name>A0A518ILZ1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">FtsK-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_00380</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4 5">Mal33</strain>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <source>
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    </evidence>
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</entry>
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            <authorList>
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                <person name="Boedeker C."/>
                <person name="Pinto D."/>
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                <person name="Kohn T."/>
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                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
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                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
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                <person name="Bruemmer F."/>
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                <person name="Spormann A.M."/>
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                <person name="Overmann J."/>
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<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
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                <person name="Lage O.M."/>
                <person name="Pohl T."/>
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                <person name="Devos D.P."/>
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                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <source>
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        <source>
            <dbReference type="EMBL" id="QDV54348.1"/>
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    <evidence type="ECO:0000313" key="4">
        <source>
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        </source>
    </evidence>
    <sequence length="901" mass="97839" checksum="91BECC330E5DDBA2" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMP8</accession>
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    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_03240</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021721976" evidence="2">
        <location>
            <begin position="21"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="187"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="228"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="298" mass="28715" checksum="1C3C8B62BBDF59E7" modified="2019-10-16" version="1" precursor="true">MRCRIVTWNRVAVASIAVMAIGSTGCKTTMPGKNLFSWGKKPSAETLAGSGPSATYPAPPSENHTPTAIASAATGKSGQSANTQVAASTTTAPASPYGSASPYGTPGGSSPYGTPTAAAQANGYNSTAAASPYGGVTPTSPYGGAAPGAAPSSPYGAAAPYAATPSTPPTYTASAANNPAYGAATPASPYATPASSTSPYAAPSPAGYTAPAAPGGYAAPPATQATYANPAAPATPATQVASSPSGYRPGSTSSATAYPGMNSSVAPSTYTTPATQSPGSSYSMPTATSPNNSGSIYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMQ2</accession>
    <name>A0A518IMQ2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_03090</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017504">
        <property type="entry name" value="CHP03067_Planctomycetes"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03067">
        <property type="entry name" value="Planc_TIGR03067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="160" mass="17091" checksum="92BFEC06D5FB9A31" modified="2019-10-16" version="1">MHCRGVLLLLIVLSGCGAESTPVTSQPDSFDTTDVDVMPLVGDTGIEGRWRIVSLLKNGQEAIDSSGVPIEIEFVNGRQIMTQGGMLLDDSGYVIDPGTTPNSIDIIHNAGGGKTATTQGIYEVNGDETRLCMGSQQSRPKEFASTSEYNVTVLKRITSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMW9</accession>
    <name>A0A518IMW9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GDSL-like Lipase/Acylhydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_03900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SGNH_hydro" evidence="1">
        <location>
            <begin position="41"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="549" mass="61768" checksum="90BB1CB0DF408F40" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IN59</accession>
    <name>A0A518IN59_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha</fullName>
            <shortName evidence="10">ACCase subunit alpha</shortName>
            <shortName evidence="10">Acetyl-CoA carboxylase carboxyltransferase subunit alpha</shortName>
            <ecNumber evidence="10">2.1.3.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10 13" type="primary">accA</name>
        <name evidence="13" type="ORF">Mal33_04800</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>acetyl-CoA + N(6)-carboxybiotinyl-L-lysyl-[protein] = malonyl-CoA + N(6)-biotinyl-L-lysyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:54728"/>
            <dbReference type="Rhea" id="RHEA-COMP:10505"/>
            <dbReference type="Rhea" id="RHEA-COMP:10506"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:83144"/>
            <dbReference type="ChEBI" id="CHEBI:83145"/>
            <dbReference type="EC" id="2.1.3.15"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Lipid metabolism; malonyl-CoA biosynthesis; malonyl-CoA from acetyl-CoA: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the AccA family.</text>
    </comment>
    <dbReference type="EC" id="2.1.3.15" evidence="10"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00655">
        <property type="reaction ID" value="UER00711"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009317">
        <property type="term" value="C:acetyl-CoA carboxylase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003989">
        <property type="term" value="F:acetyl-CoA carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016743">
        <property type="term" value="F:carboxyl- or carbamoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001295">
        <property type="term" value="P:malonyl-CoA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00823">
        <property type="entry name" value="AcetylCoA_CT_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001095">
        <property type="entry name" value="Acetyl_CoA_COase_a_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011763">
        <property type="entry name" value="COA_CT_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42853">
        <property type="entry name" value="PTHR42853"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03255">
        <property type="entry name" value="ACCA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01069">
        <property type="entry name" value="ACCCTRFRASEA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00513">
        <property type="entry name" value="accA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50989">
        <property type="entry name" value="COA_CT_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 10" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="6 10" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="13" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 10" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8 10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CoA carboxyltransferase C-terminal" evidence="12">
        <location>
            <begin position="32"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="6"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="QDV54525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="324" mass="36035" checksum="417813AFEDCFF855" modified="2019-10-16" version="1">MDAGTTLDFEKSVAELQQQLAAIEKQTDRSDAAETEIRNLRRQINEELRQIYANLDPWQTVQVARHKDRPYTNDYLKLAFDEFVELHGDKQFGDDRALLTGFAKIDRFKVIVAGHQKGRTYKERAACHFGCAHPEGYRKAMSKMKMAEKYRLPLICFIDTPGAYPGVGAEERGQAQVIAESMFQMSRLKTPIICVVIGEGGSGGALGIGVGDRVAVMENAYYSVISPEGCAGILWKSHEHAPKAAKALKFTSKDLPGLGVVDDVLPEPLGGAHRDHHQAASRLRSYLTRTLTQLESLPVEELLAQRYEKFRRMGVFLEAAEAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INF7</accession>
    <name>A0A518INF7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Maltodextrin phosphorylase</fullName>
            <ecNumber evidence="6">2.4.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">malP_1</name>
        <name evidence="6" type="ORF">Mal33_05840</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[(1-&gt;4)-alpha-D-glucosyl](n) + phosphate = [(1-&gt;4)-alpha-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:41732"/>
            <dbReference type="Rhea" id="RHEA-COMP:9584"/>
            <dbReference type="Rhea" id="RHEA-COMP:9586"/>
            <dbReference type="ChEBI" id="CHEBI:15444"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="EC" id="2.4.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycogen phosphorylase family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.1" evidence="6"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008184">
        <property type="term" value="F:glycogen phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102250">
        <property type="term" value="F:linear malto-oligosaccharide phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102499">
        <property type="term" value="F:SHG alpha-glucan phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011834">
        <property type="entry name" value="Agluc_phsphrylas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000811">
        <property type="entry name" value="Glyco_trans_35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024517">
        <property type="entry name" value="Glycogen_phosphorylase_DUF3417"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11897">
        <property type="entry name" value="DUF3417"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00343">
        <property type="entry name" value="Phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000460">
        <property type="entry name" value="Pprylas_GlgP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02094">
        <property type="entry name" value="more_P_ylases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DUF3417" evidence="5">
        <location>
            <begin position="23"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="4">
        <location>
            <position position="611"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000460-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF11897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV54629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="850" mass="95723" checksum="6A9364528EBBB8F7" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INF9</accession>
    <name>A0A518INF9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_05760</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="211" mass="23718" checksum="D4E6A3C5624CF941" modified="2019-10-16" version="1">MQRFTILLFVFVAGCREQPGAPTAATPQVERVDEVVGTEGHSANGPQLSEAIVGGIVLKPNVVIDGKLSLLLPEDFSEMDEERLKLKYPNELRPTLVYTNESAAINVAINHTTKRMRRSEIDAFHKQMEGTYRKFHPTATWFHSGVVDIDGRDWIKLDLRTPASDTEIRNIMVGTSVDGRLLLVSFNVTMQLEDQWLEAAETIIQSLRVRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INR6</accession>
    <name>A0A518INR6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_06960</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011444">
        <property type="entry name" value="DUF1549"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022655">
        <property type="entry name" value="DUF1553"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07583">
        <property type="entry name" value="PSCyt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07587">
        <property type="entry name" value="PSD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022197657" evidence="1">
        <location>
            <begin position="24"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="domain" description="PSCyt2" evidence="2">
        <location>
            <begin position="237"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="domain" description="PSD1" evidence="3">
        <location>
            <begin position="471"/>
            <end position="693"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV54736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="730" mass="81293" checksum="4B06D32E7ED98CE2" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INW3</accession>
    <name>A0A518INW3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">pknB_5</name>
        <name evidence="9" type="ORF">Mal33_07490</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="310"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="689"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="34"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="63"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV54784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="741" mass="82313" checksum="EBA275F50514D753" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPA4</accession>
    <name>A0A518IPA4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein ArsC</fullName>
            <ecNumber evidence="3">3.1.3.48</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">arsC_1</name>
        <name evidence="3" type="ORF">Mal33_08920</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.3.48" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036196">
        <property type="entry name" value="Ptyr_pPase_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52788">
        <property type="entry name" value="SSF52788"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021696761" evidence="2">
        <location>
            <begin position="25"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="239"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="262" mass="28120" checksum="1966B03EA1F13AAF" modified="2019-10-16" version="1" precursor="true">MNPKLSISILAATIVSAFGFPANAQLIDPVRSFVGGVEESVTSLTDDRKQLLNGVVDYVLTRAKGGTHAKLVFICTHNSRRSHLAQIWCQTAAAHYSVPGVETYSGGTEATACNIRTVHALRRAGLSAVASSQGDNPTYLVQYSDLHPPIRAFSKIFSARCNPTSGFAAILCCSQADKQCPVVSGADGRFSLQYEDPKLADGTPEEAMRYDDRSFQIAQEMFYVMLEVSKRLNGCNGDSKQCATPAPPKGDLDNGELVPAGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPC8</accession>
    <name>A0A518IPC8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_08880</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="218"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="241" mass="27151" checksum="4C9F5FB6C163DAE2" modified="2019-10-16" version="1">MSSYPTDRTGCGYAIRYIKTLLDSDAIRNHGYEAVLLAIFIASREDKLHYTKPPQFWRAELMDRFGHGSPKGFIRIRTAAVDAGLLHYVEGTRIKPGKYWTLVPDWMRPKFEAFRKRNGSNAKRSENGTANGTANGTANGTANGTLSNTHNPTPKKKRPSAFVPPSVEDVRVYCVERKNIIDAEHFVNHYTANGWVQGQGKGRPIRDWKATVRTWEKRDFAGGRSSEAPQRHETFDPSDAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPG6</accession>
    <name>A0A518IPG6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Biopolymer transport protein ExbD/TolR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Mal33_09630</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the ExbD/TolR family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003400">
        <property type="entry name" value="ExbD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30558">
        <property type="entry name" value="PTHR30558"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02472">
        <property type="entry name" value="ExbD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV54995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="162" mass="18300" checksum="BCE46C5F1DCDB042" modified="2019-10-16" version="1">MKIRNKSEGIKNELQMTSMIDIVFLLLVFFIMTFKIVEQEGDFNIKMPLASQDQQSQSDDLNIPLKVRMEADANGELQRIRLNEIDLGTDFAKLRETVVGLVGAGGGPSEGEDGQEVEIDADYNLRYEYTIEAITMVTGEKRGKETVKLIDKIKFAPTRRPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPZ8</accession>
    <name>A0A518IPZ8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_11380</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012808">
        <property type="entry name" value="CHP02453"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015996">
        <property type="entry name" value="UCP028451"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36452">
        <property type="entry name" value="PTHR36452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09365">
        <property type="entry name" value="DUF2461"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028451">
        <property type="entry name" value="UCP028451"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02453">
        <property type="entry name" value="TIGR02453"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="229" mass="26491" checksum="E00F2AF543ECA96B" modified="2019-10-16" version="1">MSSRSIYTDDCLLFLEELRHNNDRAWFAENKERYEASVREPSLRLIEAIGPRLEKLSPFFPAVPKRVGGSLMRIHRDTRFAKDKTPYKTNVGIHFRHEVGKDVHAPGFYIHIEPERCFVGAGCWRPASPALLAIRRKIDDEPTRWKRARDAKAFRDNYQLEGERLKTTPRDFAKDHPMIDDLRRKDFIGLSPLVESDVTSSDLVSTIIARFRAARSLMQFLCESACVPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQ40</accession>
    <name>A0A518IQ40_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Bicarbonate transport ATP-binding protein CmpD</fullName>
            <ecNumber evidence="5">3.6.3.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">cmpD_1</name>
        <name evidence="5" type="ORF">Mal33_11600</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.6.3.-" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="2"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="34"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV55190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="246" mass="27279" checksum="D04AF11E1734E23B" modified="2019-10-16" version="1">MIVADSLNLSIDGQSIIETLDLQIAAGEFVAIVGPSGCGKTSLLRMVADLQRPSGGSLKLSVADRDRPPIAYVFQDPTLLPWRTVLENIALPLELAGKSRREATAAATGVLSMVGLRDDDRNKLPAMLSGGMRMRVSLARAVVMQPQIMLFDEPFAALDDLLRSRLNEQILQLWRQQRWTGLFVTHNVSEAIFLSNRVLVMTDRPARIAEIVDVPFDHPREASLRSSIEFNRLTEHLTQLLRGEAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQ98</accession>
    <name>A0A518IQ98_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Probable 2-phosphosulfolactate phosphatase</fullName>
            <ecNumber evidence="3">3.1.3.71</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">comB</name>
        <name evidence="8" type="ORF">Mal33_12390</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>(2R)-O-phospho-3-sulfolactate + H2O = (2R)-3-sulfolactate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:23416"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15597"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58738"/>
            <dbReference type="EC" id="3.1.3.71"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ComB family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.71" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050532">
        <property type="term" value="F:2-phosphosulfolactate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005238">
        <property type="entry name" value="ComB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036702">
        <property type="entry name" value="ComB-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37311">
        <property type="entry name" value="PTHR37311"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04029">
        <property type="entry name" value="2-ph_phosp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142823">
        <property type="entry name" value="SSF142823"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00033711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV55269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="247" mass="25682" checksum="6ECD2E8C64FE4E24" modified="2019-10-16" version="1">MKSVSVALLPSLIQRESLADCTAVVIDVLRATSVIATALCNGAAGVIACESIDQAQRQAADLPGAYKLCGERGGLPIDGFDLGNSPAEYPREVIADKTVVMTTTNGTRALAAVDTAADVLTASFLNLSAASDYCAQSADVLLVCAGTDGQISGEDVLLAGAIAKRLIGGHGFETTDDSALLAIAAWEAAEPVAADPARLADFLALSKGGRNLQRIGFADDLQRVARIDSVSLVPRRESRNPLWLRCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQH6</accession>
    <name>A0A518IQH6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Isoprenylcysteine carboxyl methyltransferase (ICMT) family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Mal33_13080</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007318">
        <property type="entry name" value="Phopholipid_MeTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04191">
        <property type="entry name" value="PEMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="29"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="95"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV55337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="141" mass="15616" checksum="D942AA3E400FC170" modified="2019-10-16" version="1">MSRLLVAIQVVASAAIVLSARPTGEYPIGMTIAAAGIALGAWAIASMGIRSVSVMPELKSQTQLTTTGPYRFIRHPMYTALLTFTAGLAFSPFAIWKLVLWAIILAVLIAKAKIEEQQLRDRFPEYDRYAQQTKRFLPYIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQJ2</accession>
    <name>A0A518IQJ2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_13250</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="314"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="342" mass="37676" checksum="3580B3142DF28CFD" modified="2019-10-16" version="1">MKNEIKQDYRTAAEIVQALQGVRTPAQLSALDSSIEQCKRWRRRLAIASERNWHAAARDSADRLCGALDILRIRSEHAIEELKRPKNTGLEPTASSIFLDIEGLRGEFEGVSIDRANQRLTVRTSGIVLESVELGSFEIRLNWKHVKDSSPFDVIAVDSKCCAANDSVTHPHVQADSLCEGEGADAIRRALDEGRLFDFFCIVDHVLRNYNPDSAYVQLDDWNGVNCKACGDNVDRDEVIGCCKCETELCPDCSTSCESCMDRFCSECISSCESCGDDVCQTCLKSCDDCGESLCPSCLSEGTCDDCITKQNEANEDDDESTNEQPKPAVHSVRNGKVAVPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQN0</accession>
    <name>A0A518IQN0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Copper-sensing transcriptional repressor CsoR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">csoR_1</name>
        <name evidence="1" type="ORF">Mal33_13730</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003735">
        <property type="entry name" value="Metal_Tscrpt_repr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038390">
        <property type="entry name" value="Metal_Tscrpt_repr_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33677">
        <property type="entry name" value="PTHR33677"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02583">
        <property type="entry name" value="Trns_repr_metal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="92" mass="10442" checksum="12296627BFEC2B9E" modified="2019-10-16" version="1">MLSDDEKKKLNNRLRRVIGQVEAVGRMIEDEEYCVDILMQLSAATGALNKVGQIVLEQHIRTCVSEAIKSGSAKDRDEKIEELMTVFRKYGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQU6</accession>
    <name>A0A518IQU6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">GDT1 family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">mscS_1</name>
        <name evidence="9" type="ORF">Mal33_14400</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Membrane</location>
            <topology evidence="1 8">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the GDT1 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MscS (TC 1.A.23) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008381">
        <property type="term" value="F:mechanosensitive ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001727">
        <property type="entry name" value="Gdt1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045275">
        <property type="entry name" value="MscS_archaea/bacteria_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011066">
        <property type="entry name" value="MscS_channel_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011014">
        <property type="entry name" value="MscS_channel_TM-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023408">
        <property type="entry name" value="MscS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30221">
        <property type="entry name" value="PTHR30221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01169">
        <property type="entry name" value="UPF0016"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="SSF50182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82689">
        <property type="entry name" value="SSF82689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82861">
        <property type="entry name" value="SSF82861"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="50"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="91"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="119"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU365102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV55466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="323" mass="34369" checksum="1971C7B5B8A8806A" modified="2019-10-16" version="1">MQNEEPANAGEAAANGVNENLEVLKEEASNAFSSAMAGDFSQLIDMSMVYLPKAVLVILGVIVAYFVAKFVSRIAGTPVRRRVDETLGRFVSKVVFYAIMICVLLGVAGSVGINVTSFAAILGAAGFAVGLAFQGTLGNFASGILLLVFRPFKVGDVISAAGIVAKVNEIDLFTTTFDTPDNRRIIVPNSQIAGGTIENISFHKERRVDVSVGTEYSASLDLTRETLSKAAESLSDKMLTGEGRGYQIVLGELGDSAVAWTVRFWTRAEDFWGVKESLTRAVKNGLDEAGIGIPFPQLDVNLNGGPADTEAAGDGKIKPRLRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQV0</accession>
    <name>A0A518IQV0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_14060</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011467">
        <property type="entry name" value="DUF1573"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07610">
        <property type="entry name" value="DUF1573"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021770887" evidence="1">
        <location>
            <begin position="26"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="331" mass="35995" checksum="F61AC26151D7E6A7" modified="2019-10-16" version="1" precursor="true">MYRKASISSVLAVGFLVLLCGRANAQQSWAKGLFAETQHDFGAVSRGSNAEFHFDFKNTLDKDILITKLQTSCGCTQPSIAKGRIAPGETGTVVAKFNTTSFTGQKSAVVTVVFAEPQHAEVQLNVSGFIRTDVVVEPAEVNFGSFRDGDAKPVTLKISYTGNSAWRIEDVRSQFSQLQVSLERRDTSARGISYLMKVGLKKDSPVGEFRERMTLITNEQKTPTIALDVIGRVEPDLILTPASLNLGSVPKGGMISKRLVLRGPEAFEVKDIKCKDLRFQFTKPEGKKKLHFVNVQFASGQAAGKIFDSIEIQTDLNGGSNATCPVSGEVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQX7</accession>
    <name>A0A518IQX7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_14440</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="380" mass="42840" checksum="A4578986CAFF0477" modified="2019-10-16" version="1">MAQNIDFLEPRLVGDRFNGHSIPLEVLKDLSALEELLVEVAKWHYRNENPERKRIPKGFADDVSLKVTEIGDGSAIPKIVLCVSSATGTLFPVDHREYFAKAKESVVTAIDNAHHQRSVAGILLDSHLAYFDRIGRSLRDNEALELNYPDTKRPAQINRTTRRYLTLAASSAGGFTEEVTLRGSVCEADQRKDRFQLRLIDGRIIGAPIQSEHRETILDAFHRFRHGVRVIIDGVGRYNRRNRLDGLESVEHISLLDPLDVGARLEEFTSLSNGWLEGRGIAPKADDLDWLTDQFEANYSDRLPAPYLYPTGEGGVQAEWSLDQWEATLDIDLKSKSAYWHALNQSNDEESEHEIDLSSLDGWKWLADQLTQLVPGDSDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IR09</accession>
    <name>A0A518IR09_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative voltage-gated ClC-type chloride channel ClcB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Mal33_15050</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015299">
        <property type="term" value="F:solute:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006812">
        <property type="term" value="P:cation transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0129">CBS domain</keyword>
    <keyword evidence="3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="93"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="119"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="151"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="192"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="219"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="292"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="331"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="6">
        <location>
            <begin position="501"/>
            <end position="560"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV55528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="561" mass="60431" checksum="F96CB5EE9ECE4ADC" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IR36</accession>
    <name>A0A518IR36_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF2344 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_15170</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018768">
        <property type="entry name" value="DUF2344"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10105">
        <property type="entry name" value="DUF2344"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03936">
        <property type="entry name" value="sam_1_link_chp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2344" evidence="1">
        <location>
            <begin position="5"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="223" mass="25148" checksum="BB958F0401F13B4E" modified="2019-10-16" version="1">MTRARYHIRFSKTGPLRWISHRDLLRLWERLFHRIDLKLAMSEGFHPKPRMNFPSALALGTASLDELLELELTEPLDPQELAGRLQADQQPGLGILQVTAVPEGSAKAKLKSTTYNLPIPESDRAALLAEIEALRSRDTIEIKRKDKTLVFSLAAEIEHLAVEDGVLVFRCTPDQGASLRPTDLIQELKITHVTDSGQFLTRTRVELEHEFESSRCVTGQMTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRC7</accession>
    <name>A0A518IRC7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Diacylglycerol kinase</fullName>
            <ecNumber evidence="3">2.7.1.107</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">dagK_1</name>
        <name evidence="3" type="ORF">Mal33_16290</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.1.107" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004143">
        <property type="term" value="F:diacylglycerol kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003951">
        <property type="term" value="F:NAD+ kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017438">
        <property type="entry name" value="ATP-NAD_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001206">
        <property type="entry name" value="Diacylglycerol_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045540">
        <property type="entry name" value="YegS/DAGK_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00781">
        <property type="entry name" value="DAGK_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19279">
        <property type="entry name" value="YegS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00046">
        <property type="entry name" value="DAGKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="SSF111331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50146">
        <property type="entry name" value="DAGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DAGKc" evidence="2">
        <location>
            <begin position="3"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="304"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="308"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="328" mass="35861" checksum="BE9B0C23CA24528D" modified="2019-10-16" version="1">MNESPEVVLICTSPKAGSGQRRDLVPKLAHALTDRGLEVRSTSNIDQLAADAKSLTAAGRLKGVVAAGGDGTLSLVVSRLPAESPVMPLPLGTENLMARYLGHRPSAEDAADTIMRQRTVVMDAALAGERLFLIMCSCGFDAEVVRRLHTTRSGHIWKLSYLAPVLRSMIGYHFPSLRLIDRQSDEQPVPARWAFVFNVPRYAVGLPIAAWADGTDGWLDSVTFDKGSVYRALHYLAHIFRRSHHTLDGTIIGRSRRFTIEPTDPAAKIPYQLDGDFVGYLPVEIAVQPSRVTMLLPQHCPVEFKTDTGGHHSTNAQPSREPAGQPLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRK5</accession>
    <name>A0A518IRK5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L13</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 6" type="primary">rplM</name>
        <name evidence="6" type="ORF">Mal33_16990</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL13 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00392">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01366">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005822">
        <property type="entry name" value="Ribosomal_L13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005823">
        <property type="entry name" value="Ribosomal_L13_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036899">
        <property type="entry name" value="Ribosomal_L13_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11545">
        <property type="entry name" value="PTHR11545"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00572">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002181">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52161">
        <property type="entry name" value="SSF52161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01066">
        <property type="entry name" value="rplM_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="131"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="133"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV55720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="153" mass="17476" checksum="31821B90EA2FB7F7" modified="2019-10-16" version="1">MPSQRTYNAKPGEVEKSWYIVDATDQTLGRLASDIAVVLMGKHRPEYTPHIDVGDFVIVTNVESIKMTGRKMEQRHYTWYTGHPGLRLESYQGRQERKPEDLLYHAVRRMLPKNKIARHMLTKLKIYTGGEHPHQAQQPQPLTGAGKVIASSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRM0</accession>
    <name>A0A518IRM0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Phosphoglucomutase</fullName>
            <ecNumber evidence="10">5.4.2.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">pgcA</name>
        <name evidence="10" type="ORF">Mal33_16720</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the phosphohexose mutase family.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.2" evidence="10"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004614">
        <property type="term" value="F:phosphoglucomutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005844">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016055">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I/II/III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005845">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005846">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005843">
        <property type="entry name" value="A-D-PHexomutase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036900">
        <property type="entry name" value="A-D-PHexomutase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016066">
        <property type="entry name" value="A-D-PHexomutase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02878">
        <property type="entry name" value="PGM_PMM_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02879">
        <property type="entry name" value="PGM_PMM_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02880">
        <property type="entry name" value="PGM_PMM_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00408">
        <property type="entry name" value="PGM_PMM_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53738">
        <property type="entry name" value="SSF53738"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55957">
        <property type="entry name" value="SSF55957"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00710">
        <property type="entry name" value="PGM_PMM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PGM_PMM_I" evidence="7">
        <location>
            <begin position="72"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_II" evidence="8">
        <location>
            <begin position="240"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_III" evidence="9">
        <location>
            <begin position="352"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_IV" evidence="6">
        <location>
            <begin position="551"/>
            <end position="588"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV55693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="611" mass="66214" checksum="63E5FD933109E884" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRS5</accession>
    <name>A0A518IRS5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">EF hand</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_17780</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13202">
        <property type="entry name" value="EF-hand_5"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="SSF47473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022008264" evidence="2">
        <location>
            <begin position="26"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="74"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="155"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV55799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="241" mass="26048" checksum="AF62F2B475B381E5" modified="2019-10-16" version="1" precursor="true">MRYRHFAATAALLVSVGVSAGIAVAQDGPGDGDRPRPRDGGPRDRGPRDGAPRLPPIPVLEALDSNGDGMLDATEIEQAAKALKSLDRDNDGVLSFQEMMPAPRGDRGPGGPQGRGDRPEMRDGQGRPDGEGRPRRPDGEGRRPRPEGEGNRRGGNPEQFVERIMKLDKDGDGKLSGEELPERMRAMLSRADVDGDDALSKEELMKMAERRGRQGGGEGRRRPDGEKPTEGGERPRRPPAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRY1</accession>
    <name>A0A518IRY1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 7">ATP-dependent Clp protease proteolytic subunit</fullName>
            <ecNumber evidence="5">3.4.21.92</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Endopeptidase Clp</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">clpP_2</name>
        <name evidence="5" type="synonym">clpP</name>
        <name evidence="8" type="ORF">Mal33_18210</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 7">Belongs to the peptidase S14 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.92" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07017">
        <property type="entry name" value="S14_ClpP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00444">
        <property type="entry name" value="ClpP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001907">
        <property type="entry name" value="ClpP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023562">
        <property type="entry name" value="ClpP/TepA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033135">
        <property type="entry name" value="ClpP_His_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10381">
        <property type="entry name" value="PTHR10381"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00574">
        <property type="entry name" value="CLP_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00127">
        <property type="entry name" value="CLPPROTEASEP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00382">
        <property type="entry name" value="CLP_PROTEASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5 8" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0720">Serine protease</keyword>
    <feature type="active site" description="Nucleophile" evidence="5">
        <location>
            <position position="100"/>
        </location>
    </feature>
    <feature type="active site" evidence="5 6">
        <location>
            <position position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV55842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="206" mass="22633" checksum="A160839B8E93EFBE" modified="2019-10-16" version="1">MNQEIWNSHSYQSVQRQRQLTLGDLLLENRIVFLQGEIHTGNANEVVMKLLYLQSENRRKDVHFYINSPGGDVIATLAIYDTMQMLSCPIATYCVGQAASGGAVLLVGGTKGKRYALPHSRVMMHQPAGGVGGQISDIEIHANEILRYRDVLNGILAEHTGQTVEKIAHDTDRDFFLTAQAAKEYGIVDDILTKPPVGAEDEAAKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IS39</accession>
    <name>A0A518IS39_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Calx-beta domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Mal33_18790</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007154">
        <property type="term" value="P:cell communication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2030">
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013425">
        <property type="entry name" value="Autotrns_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006644">
        <property type="entry name" value="Cadg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015919">
        <property type="entry name" value="Cadherin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038081">
        <property type="entry name" value="CalX-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003644">
        <property type="entry name" value="Calx_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002105">
        <property type="entry name" value="Dockerin_1_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036439">
        <property type="entry name" value="Dockerin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043710">
        <property type="entry name" value="DUF5650"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040853">
        <property type="entry name" value="RapA2_cadherin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17803">
        <property type="entry name" value="Cadherin_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03160">
        <property type="entry name" value="Calx-beta"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00404">
        <property type="entry name" value="Dockerin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18888">
        <property type="entry name" value="DUF5650"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="SMART" id="SM00736">
        <property type="entry name" value="CADG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00237">
        <property type="entry name" value="Calx_beta"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141072">
        <property type="entry name" value="SSF141072"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49313">
        <property type="entry name" value="SSF49313"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63446">
        <property type="entry name" value="SSF63446"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02601">
        <property type="entry name" value="autotrns_rpt"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Calx-beta" evidence="4">
        <location>
            <begin position="3389"/>
            <end position="3484"/>
        </location>
    </feature>
    <feature type="domain" description="Calx-beta" evidence="4">
        <location>
            <begin position="3500"/>
            <end position="3595"/>
        </location>
    </feature>
    <feature type="domain" description="Calx-beta" evidence="4">
        <location>
            <begin position="3611"/>
            <end position="3706"/>
        </location>
    </feature>
    <feature type="domain" description="Calx-beta" evidence="4">
        <location>
            <begin position="3722"/>
            <end position="3819"/>
        </location>
    </feature>
    <feature type="domain" description="CADG" evidence="5">
        <location>
            <begin position="4078"/>
            <end position="4177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="4292"/>
            <end position="4322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="4292"/>
            <end position="4307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="4308"/>
            <end position="4322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV55900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="4334" mass="439328" checksum="CCC901B120F22571" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISA1</accession>
    <name>A0A518ISA1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Arylsulfatase</fullName>
            <ecNumber evidence="6">3.1.6.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">atsA_13</name>
        <name evidence="6" type="ORF">Mal33_19300</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="PTM">
        <text evidence="3">The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the sulfatase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.6.1" evidence="6"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004065">
        <property type="term" value="F:arylsulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024607">
        <property type="entry name" value="Sulfatase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00523">
        <property type="entry name" value="SULFATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022141782" evidence="4">
        <location>
            <begin position="21"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase" evidence="5">
        <location>
            <begin position="32"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="modified residue" description="3-oxoalanine (Cys)" evidence="3">
        <location>
            <position position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR600917-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV55951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="478" mass="52620" checksum="92E7761E9B1E3C6A" modified="2019-10-16" version="1" precursor="true">MQRRPIRWMLLSLFFTPWLAAAGADDSATTKPNIILVMADDQGWGDMAYNGHPIVQTPNFDDAAATGLRFDRFYAAAPVCSPTRASVLTGRHPNRSGVFQWGFPLRPQEITIAEALKTAGYTTGHFGKWHLGSVRSGSPANPTAHGFDEWFSAPNFYDNDAIMSHRGKAVKTVGESSAIAVDAAMQWIDDVRKKPEPFLAVVWFGSPHVPHQAAPEDSALYKDQNKRMREFLGEVTGMDRAFGKLRDGLGERGLRENTILWYCSDNGALPRVGSTGGHRGLKGKVYDGGLLVPAILEWPTKIPRPRTTSVRCNTTDIYPTLLDVAGVKMENQPIVDGISLLPLIEEKVTERAKPMGFWNYAIKGIITPSAVWMGELYAAQQAGNDLPPDPASANAATLPSEPVVHAQGHSAWIDGDWKLHRIENDGKAKFELYDLASDPKEENDLYAKQSKSPRATEMQQALEAWLTSVDASYLGKDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISE5</accession>
    <name>A0A518ISE5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_19800</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017039">
        <property type="entry name" value="Virul_fac_BrkB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30213">
        <property type="entry name" value="PTHR30213"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03631">
        <property type="entry name" value="Virul_fac_BrkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF035875">
        <property type="entry name" value="RNase_BN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00765">
        <property type="entry name" value="yihY_not_rbn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="21"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="94"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="142"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="185"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="218"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="250"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV56001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="304" mass="32863" checksum="EFB22F9687F2472B" modified="2019-10-16" version="1">MDFLKQTFSEFSKDRCTTLAAALAYYTTFALPPLLYLLLTVLTYGLSVAYESDRAHDKAEAVLEDQAADMLGNPAAAEGITTILQQNRESSGTWWKTAISFVGIIVGATGVVGALQDALNRVWEVKPNPNASTLWTIISKRLLSFAMILGLGFLLLVSLVVSSVLSTAGQQLGELIGISGIVARTINYSVQAAVVFTIFAAIFRFMPDADVRWRDVMVGAAITTALFLVGRWGMQIYFGFSEPGAQLGSAAASLAVILVWVYYSAMIVLLGAEATQVYAARFGHGIQPEKHAVQVVEQVRHSRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISE8</accession>
    <name>A0A518ISE8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_20050</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="247" mass="28661" checksum="06084F41865D8B2F" modified="2019-10-16" version="1">MSGYDAFSDDYYMNMHLSTELDMPRDRESVMHFFEQIQRRYRSMQNFYAREKNEFVLEEDKEAGQYNWASVEPRRVSCGAVNPKSLDDVVARHRTILETAPYALSISPLECESLSVMFGFDFTYRGNQNELLAEALGVLPAFDKALEVPGISLLSHEPSIQFALDDQCRTQCRIGFETRTTAYQIRTTEFSEDQLSVYLTIRRFDSLSVGENFVEEYDRLARLGRNLVEDYLIENVLRPLQQTIALH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISI6</accession>
    <name>A0A518ISI6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF2760 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_20300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021212">
        <property type="entry name" value="DUF2760"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10816">
        <property type="entry name" value="DUF2760"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2760" evidence="2">
        <location>
            <begin position="62"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="186" mass="19815" checksum="FA8D1EF5C7259860" modified="2019-10-16" version="1">MSIGLAIQAFFKILFNREAAAAYQRLTSGEAVDQPTPAAAESTPAEAPAKAQAPAPPKPTRSDAIGLLAALQREARFVDLVQESLDAYSDEQVGAAARDVLRDTKKVLDRMFAIAPLTESEEGDSMQTPAEVDPGQIRLTGNVHGDAPFSGTIAHHGWKAAKCELPRWSGSPESDRVIAPIELEIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IT42</accession>
    <name>A0A518IT42_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_22400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011089">
        <property type="entry name" value="DUF1524"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004919">
        <property type="entry name" value="DUF262"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07510">
        <property type="entry name" value="DUF1524"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03235">
        <property type="entry name" value="DUF262"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF262" evidence="1">
        <location>
            <begin position="17"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1524" evidence="2">
        <location>
            <begin position="438"/>
            <end position="597"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="611" mass="71219" checksum="C6BE718EECB0DAD0" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IT81</accession>
    <name>A0A518IT81_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cellulase (Glycosyl hydrolase family 5)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_22730</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071704">
        <property type="term" value="P:organic substance metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00150">
        <property type="entry name" value="Cellulase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cellulase" evidence="3">
        <location>
            <begin position="98"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV56291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="396" mass="45005" checksum="781C808FBD337061" modified="2019-10-16" version="1">MSNCIAANTRPLLAVLVRTLLLRRISRKVVQFGLLVVFFATHATAQPFQRVRVSDDGNYFAIGESQQRFVVWGVNYDHNSEGELLDEYWIERWEEVVEDFAEMKALGANCVRIHLQFGKFMNAADQPNQTALDQLAKLLKLAEETGLYLDITGLACYHKANVPEWFDRLSEQDRWKTQALFWGSIAQVCRNSPAVFCYDLMNEPILPGKRKSGEPAESQWLGGELGGKFFVQRLALDLAGRTRQQVAKAWVDQMVDAIREQDELHMITVGVIPWVFVFGGGKPLFYSSEVGERLDFVSVHFYPEKGQVEEAITALRAYDIGKPLVVEEMFPMKCSVAELEEFVSQSSEFTDGWISFYWGKTADQLNQKSNPTIAEAITASWLQRFQSMAEQVTKTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IT96</accession>
    <name>A0A518IT96_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator PleD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">pleD_3</name>
        <name evidence="3" type="ORF">Mal33_22970</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="5"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="148" mass="16747" checksum="99FAA53A79915C6F" modified="2019-10-16" version="1">MPADRILIADDNEANRELLDAYLANVECEIEHAVDGADCMAKVESFSPDLILLDVMMPQLSGFEVCKKIKQNPATQQIIVLMVTALNELGDIERAVESGTDDFLTKPVNKFQLLKRVENMLKLKGTRDELERLRAYIREMEEQSEPHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITE9</accession>
    <name>A0A518ITE9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phosphate-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">pstS_1</name>
        <name evidence="6" type="ORF">Mal33_23480</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the PstS family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042301">
        <property type="term" value="F:phosphate ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035435">
        <property type="term" value="P:phosphate ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005673">
        <property type="entry name" value="ABC_phos-bd_PstS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024370">
        <property type="entry name" value="PBP_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12849">
        <property type="entry name" value="PBP_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002756">
        <property type="entry name" value="PstS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00975">
        <property type="entry name" value="3a0107s03"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021861997" description="Phosphate-binding protein" evidence="4">
        <location>
            <begin position="25"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="domain" description="PBP_domain" evidence="5">
        <location>
            <begin position="32"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR002756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF12849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV56361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="349" mass="37448" checksum="389B5CEDCEE2D4B3" modified="2019-10-16" version="1" precursor="true">MNVRIKLMLVIAAMAVFVGCNKPASDNPVDETLGIRGAGATFPAPLYKKWIQEYQAAFPDRHVAYAATGSGDGVDQFIAGTVDFGGSDAGLLPDEEAKVSRGAVTIPVTGGVLVLAYNLPGLSEPLKLSRDVYVDIFLGEIKRWNDSRIVADNPNLQLPALDIVVVARQDGSGTTYAFTNHLSTISEQWKTEGPGTGKLIDWPGSTMLANGNGGVAGQIQRSHGSIGYVQYGIAEHAKLQMASLENRAGKFVAPTGQSGMQTLEHAELPENLQAFFPDPKGDDSYPIVTLTWLLLYENYASSEKGEAVEHFVAWCLEEGQGFSESLGYIKLSPRVLEAATKALNRVSSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IU43</accession>
    <name>A0A518IU43_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">YHS domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_26070</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.620.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012348">
        <property type="entry name" value="RNR-like"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022198321" evidence="2">
        <location>
            <begin position="30"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="234" mass="25320" checksum="5894CECFEE27E739" modified="2019-10-16" version="1" precursor="true">MLNQRFGLRSLSAAVTLSMCLVITSQVDAQSGTRAPRPAQPPASGGSQNRAPQPAAGGSQSRAAQAKIAMDGYCPVCVIDMKKWVRGTTQHQVAYDGKVYLFPGEEQKQVFLADPAKYVPALGGDCTVCSVNMSQRMPGKVQHAALYGGRLYLFPGEEQKEVFRADPAKYANVDLAMKGLCSVCRVEMQQDVPGKPEIATVHQGLRYLFPSDEQRQMFLANPAKYAVPANAPLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IU72</accession>
    <name>A0A518IU72_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Phosphate transport system permease protein PstA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">pstA_1</name>
        <name evidence="6" type="ORF">Mal33_26380</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="24"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="75"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="125"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="254"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="303"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="374"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="79"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV56645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="405" mass="44000" checksum="E27B99FBF83D4EA6" modified="2019-10-16" version="1">MSEADYQVPAVDPQRAKNRHTISAIFRVACMLVAVQAVVILIVLLTTVFVRGVDQLSWDFLTGVHRDDNPDGSGLWPAIIGSIVICLICGAAALPIGIGTAIFLEEFKPRNKALAVLHNLVQLNITNLAGVPSIVYGILGLTAFVYMFGLFGTYEANKAADLEFGAQRYYQVRTAAKTFVWIPVTDKTLRVLEIEEPIAARYPDGGDFTLNVIDRGATKPTDPTLLGQTVYRGSKASIFAKHPWHYLRLPFHKSVLSAGLTLALVVLPIVIISSQESIRAVPDTMRDAGLGLGCTRWQMVRTIVLPASIPGIMTGAILAMSRAVGEAAPLLAVMGGVVGKRNAPENLMDNAAAMPITIYNWARDDNPGFWELSATAIIVLLCLLLTMNSIAILLRYWAEKKFASR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUC6</accession>
    <name>A0A518IUC6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Asparagine synthetase [glutamine-hydrolyzing] 1</fullName>
            <ecNumber evidence="10">6.3.5.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">asnB_2</name>
        <name evidence="10" type="ORF">Mal33_26870</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the asparagine synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.4" evidence="10"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004066">
        <property type="term" value="F:asparagine synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006529">
        <property type="term" value="P:asparagine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01991">
        <property type="entry name" value="Asn_Synthase_B_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00712">
        <property type="entry name" value="AsnB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006426">
        <property type="entry name" value="Asn_synth_AEB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001962">
        <property type="entry name" value="Asn_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033738">
        <property type="entry name" value="AsnB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00733">
        <property type="entry name" value="Asn_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13537">
        <property type="entry name" value="GATase_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001589">
        <property type="entry name" value="Asn_synthetase_glu-h"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01536">
        <property type="entry name" value="asn_synth_AEB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0061">Asparagine biosynthesis</keyword>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 5" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="10" id="KW-0436">Ligase</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="9">
        <location>
            <begin position="2"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="active site" description="For GATase activity" evidence="5">
        <location>
            <position position="2"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="298"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="370"/>
            <end position="371"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for beta-aspartyl-AMP intermediate formation" evidence="7">
        <location>
            <position position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001589-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001589-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR001589-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV56689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="635" mass="73050" checksum="C54B52ABFADADE86" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUF3</accession>
    <name>A0A518IUF3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_27240</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="71" mass="7833" checksum="C41122826A4C3C2E" modified="2019-10-16" version="1">MSKDSRASIPGIVKDGVIVPQASQQLAEGTHVEIVVEPESIPAELRAEMLAWDQASDEAWAMIEKWEAEEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUG0</accession>
    <name>A0A518IUG0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type II secretion system protein G</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">xcpT_5</name>
        <name evidence="2" type="ORF">Mal33_27200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011453">
        <property type="entry name" value="DUF1559"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027558">
        <property type="entry name" value="Pre_pil_HX9DG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07596">
        <property type="entry name" value="SBP_bac_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04294">
        <property type="entry name" value="pre_pil_HX9DG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="297" mass="33281" checksum="07C5F6F00208A500" modified="2019-10-16" version="1">MKMNNTRRAGFTLVELLVVIAIIGILVGLLLPAVQQAREAARRMQCKNRLKQIALALHNYADTYRETMIPYVVEDQARINYLATYSGAQGKAQFWFGTVDYDQPDPNQQLDYTQGPLAPFIETSYTSFQCPDFGPGQMDTVKYGFPASGFGFNGYNLSRSSGVDWLPPTYAAVPNPEPMVRRFAEVRSMSATVAFADSAQVKLVSFSPPAYSFEENWLLDPPSHNFPNVHFRHHGAANVAFLDGHVESRQRHFKIDVPGTNYMSAEQAALIDEKKLGYVSDGHLDDPALQDELYDRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUM5</accession>
    <name>A0A518IUM5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">FAD:protein FMN transferase</fullName>
            <ecNumber evidence="3 9">2.7.1.180</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">apbE_2</name>
        <name evidence="10" type="ORF">Mal33_27860</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>FAD + L-threonyl-[protein] = AMP + FMN-L-threonyl-[protein] + H(+)</text>
            <dbReference type="Rhea" id="RHEA:36847"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11061"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:74257"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.7.1.180"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the ApbE family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.180" evidence="3 9"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017013">
        <property type="term" value="P:protein flavinylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024932">
        <property type="entry name" value="ApbE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003374">
        <property type="entry name" value="ApbE-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014469">
        <property type="entry name" value="DUF2271"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30040">
        <property type="entry name" value="PTHR30040"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02424">
        <property type="entry name" value="ApbE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10029">
        <property type="entry name" value="DUF2271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143631">
        <property type="entry name" value="SSF143631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0274">FAD</keyword>
    <keyword evidence="5 9" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="10" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="8 9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="6 9" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
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            <end position="496"/>
        </location>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001219"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00011955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363002"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="QDV56787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="496" mass="54793" checksum="03D7D341D6AB00FF" modified="2019-10-16" version="1" precursor="true">MFRIPLTLIAAIFLSASLSADEHRFQHENVLGTSLTLDVHVASPQLARTIESESLTEIGRLDAIFSSYRDDSELSRWLKQPVGVDAALSVELIAVLQRAEHVRRESHGAFDIRAAAIAELWKSEAKAGRSPSDASRNQMVQSLAEPVVSFSNERVRRLTDHRINLDSLAKGYILDRVCEVVSKHLSPGDRFSINVGGDLRTIGDGATKIVITDPRRPSENAKPLVEFTAHGEVAVATSGTYRRSLQIGEREVSHLFDPRSALPVGHTISASVIAADAITADALATTISVLPTHEAIQWIDAKPGCECLIVDEKGKVHRSANWPAANPSPASRLIAAADAKQAGIHVWFKLERPSGSSYRRPYLAVWLEDEDGFPVKTAVLWMQTEQPGPRWHRDLTRWYRNDRMRKIVEKTDLIEAISGATRGPGEYEAHFDGTDNSGEPLPTGRYTLCLEAARENGTYKIIRQRIDWGTDTVEKTQLKGNIEIPQAAYQIVPAVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUM6</accession>
    <name>A0A518IUM6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nickel and cobalt resistance protein CnrA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">cnrA_1</name>
        <name evidence="2" type="ORF">Mal33_27920</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82714">
        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="333"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
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            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="387"/>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
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        </location>
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        <location>
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            <end position="487"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
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            <end position="545"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="866"/>
            <end position="883"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="890"/>
            <end position="911"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="917"/>
            <end position="942"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="969"/>
            <end position="989"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="995"/>
            <end position="1018"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1034" mass="111017" checksum="15E171DE33AF3750" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUY9</accession>
    <name>A0A518IUY9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lipopolysaccharide export system ATP-binding protein LptB</fullName>
            <ecNumber evidence="3">3.6.3.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">lptB_2</name>
        <name evidence="3" type="ORF">Mal33_29030</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.6.3.-" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
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        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="2">
        <location>
            <begin position="21"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="243" mass="28025" checksum="99465F5BF52AEEB3" modified="2019-10-16" version="1">MSSLEKNDPAPAEADPRREILVLEDLSFRDLTRQSVTLRDANLTIFENDLVTLTLPPSMESRAFTSMLLGLRMPQQGRVLFDGNEWTGEDYALHDRMRSQIGRVFDGKAWVENMNIYENVVLPHQHHNHRTVKELDREIQYWSRRFEIESMKNQRPAFVGKTFLRICEWIRALIGSPRLLLLEHPMRSVPRARFPALLQAVVSATEAGAAALWIAPSSDLQRDKFPTSARHYQIHDFHLTPVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IV35</accession>
    <name>A0A518IV35_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_29390</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="64" mass="6434" checksum="C0C0BD959C0AA8E3" modified="2019-10-16" version="1">MSSVNGIAQTATAIANAQLHSKVDFAVLQKQQEASQQAGGAAVQLIEAAAAVGQPVDTLELSEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IV61</accession>
    <name>A0A518IV61_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Xanthan lyase</fullName>
            <ecNumber evidence="6">4.2.2.12</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">xly_2</name>
        <name evidence="6" type="ORF">Mal33_29770</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="4.2.2.12" evidence="6"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047492">
        <property type="term" value="F:xanthan lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011429">
        <property type="entry name" value="Cyt_c_Planctomycete-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011444">
        <property type="entry name" value="DUF1549"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022655">
        <property type="entry name" value="DUF1553"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07635">
        <property type="entry name" value="PSCyt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07583">
        <property type="entry name" value="PSCyt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07587">
        <property type="entry name" value="PSD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022158320" evidence="2">
        <location>
            <begin position="20"/>
            <end position="937"/>
        </location>
    </feature>
    <feature type="domain" description="PSCyt1" evidence="5">
        <location>
            <begin position="40"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="PSCyt2" evidence="3">
        <location>
            <begin position="164"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="domain" description="PSD1" evidence="4">
        <location>
            <begin position="661"/>
            <end position="912"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="401"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="577"/>
            <end position="604"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV56976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="937" mass="103884" checksum="8DC7C889A4A0C0C5" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IV70</accession>
    <name>A0A518IV70_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Prolyl endopeptidase</fullName>
            <ecNumber evidence="6">3.4.21.26</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Mal33_29790</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S9A family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.26" evidence="6"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002471">
        <property type="entry name" value="Pept_S9_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023302">
        <property type="entry name" value="Pept_S9A_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002470">
        <property type="entry name" value="Peptidase_S9A"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02897">
        <property type="entry name" value="Peptidase_S9_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00862">
        <property type="entry name" value="PROLIGOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00708">
        <property type="entry name" value="PRO_ENDOPEP_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021834797" evidence="3">
        <location>
            <begin position="26"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S9_N" evidence="5">
        <location>
            <begin position="38"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S9" evidence="4">
        <location>
            <begin position="500"/>
            <end position="712"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV56978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="713" mass="80086" checksum="3A3DA5FBBDA580AF" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVA8</accession>
    <name>A0A518IVA8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nitrogen regulatory protein P-II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">glnB_3</name>
        <name evidence="3" type="ORF">Mal33_30230</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the P(II) protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030234">
        <property type="term" value="F:enzyme regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006808">
        <property type="term" value="P:regulation of nitrogen utilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002187">
        <property type="entry name" value="N-reg_PII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011322">
        <property type="entry name" value="N-reg_PII-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015867">
        <property type="entry name" value="N-reg_PII/ATP_PRibTrfase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017918">
        <property type="entry name" value="N-reg_PII_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30115">
        <property type="entry name" value="PTHR30115"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00543">
        <property type="entry name" value="P-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00340">
        <property type="entry name" value="PIIGLNB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00938">
        <property type="entry name" value="P-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54913">
        <property type="entry name" value="SSF54913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00638">
        <property type="entry name" value="PII_GLNB_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51343">
        <property type="entry name" value="PII_GLNB_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="O-UMP-tyrosine" evidence="1">
        <location>
            <position position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR602187-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="122" mass="13493" checksum="A96EAF730888FDBB" modified="2019-10-16" version="1">MDDRVHTPIVAYGFPFVKQVIAVVKPYLAQKVLGSLERAPIEAITVTEVKGFGRQKSYLDQYGDSEYSEAFLPKVEITAWVEDARVEEILAKLVSVARSGRMGDGKIFVMPVLGFLEEPSGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVC5</accession>
    <name>A0A518IVC5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_30380</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010869">
        <property type="entry name" value="DUF1501"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07394">
        <property type="entry name" value="DUF1501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="431" mass="46972" checksum="407CB7485471A5DD" modified="2019-10-16" version="1">MNIDCGSHDHLSRRSLLQSAGALSMTALANQLARGSEQSSKPARPKSIIILWLKGAPSQYETFDPHAGTKYGGEVAAIDTTARDVQISEFLPQTAEQMHRVALVRSVTSKEGDHERAFYNIQTGWRPDPTVVHPSIGSIVCHELPGGADIPRHISILPDNSAGRGGYLGAKYDAFKVYDPANKVPDIRPYVGEKRFQRRVDGLMDVVESNFRKGRLRDLDRDRTLHGIATKSALTMMDSDQLAAFEVDKESKALRAQFGETAFGRGCLAAARLIEVGVRCVEVGLSGWDTHADNHNGQRTQCEILDPAYATLLQVLADRDLLDSTLVVCGGEFGRTPKINPVGGRDHWPHGFSIALAGCGLRQGIVHGATSPDPKLDKEDLLTNVADPVTVQDIHATILKALDVRFERELITPIGRPLKLSEGTPIESILS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVG3</accession>
    <name>A0A518IVG3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_30700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="203" mass="22683" checksum="60447CF053C274C4" modified="2019-10-16" version="1">MSARNLSNVSKKSHEGAKKHPNQSQQSPTKAGFKNQVFERVASLVRESDCEEAVEVLRAAGFDIQIRNALGVCLMRAGRPEEAVAVFRQFVLQSDGVSERKELSNAYKRNFATALLMKGSPSGAVSVLTETHELDHPMAVRISGAIRSWAKSLSWWRRFDWKINGIEPANCHVPLDFEPGEFDFETVVRQQDLPRDGRFGLAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVG5</accession>
    <name>A0A518IVG5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Amino-acid carrier protein AlsT</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">alsT</name>
        <name evidence="9" type="ORF">Mal33_30810</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
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            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015655">
        <property type="term" value="F:alanine:sodium symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001463">
        <property type="entry name" value="Na/Ala_symport"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30330">
        <property type="entry name" value="PTHR30330"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="NAALASMPORT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00835">
        <property type="entry name" value="agcS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0769">Symport</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
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            <end position="108"/>
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        <location>
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            <end position="188"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="8">
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            <end position="248"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="8">
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            <end position="290"/>
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    <feature type="transmembrane region" description="Helical" evidence="8">
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        </location>
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    <feature type="transmembrane region" description="Helical" evidence="8">
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            <end position="408"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
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            <end position="503"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
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            <end position="541"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="547"/>
            <end position="566"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV57080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="586" mass="62715" checksum="883121FFF15F276D" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVQ2</accession>
    <name>A0A518IVQ2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_31610</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
    <dbReference type="InterPro" id="IPR035069">
        <property type="entry name" value="TTHA1013/TTHA0281-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143100">
        <property type="entry name" value="SSF143100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="81" mass="8872" checksum="20947F271740E780" modified="2019-10-16" version="1">MNAAARYVKIVEWSDEDNCYVGSCPGLFYGGCHGDDEKSVFAELCQIVEETVKLHEAENRPLPPATSGYDWANTIANATTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVR4</accession>
    <name>A0A518IVR4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Trk system potassium uptake protein TrkG</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">trkG</name>
        <name evidence="8" type="ORF">Mal33_31790</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003445">
        <property type="entry name" value="Cat_transpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02386">
        <property type="entry name" value="TrkH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="51"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="85"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
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            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
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            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
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            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
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            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
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            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
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            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
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            <end position="548"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV57178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="551" mass="60090" checksum="CFB9C7EF4B8D47B5" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVR5</accession>
    <name>A0A518IVR5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative glycerophosphoryl diester phosphodiesterase 1</fullName>
            <ecNumber evidence="3">3.1.4.46</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">glpQ1</name>
        <name evidence="3" type="ORF">Mal33_31830</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.4.46" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008889">
        <property type="term" value="F:glycerophosphodiester phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030395">
        <property type="entry name" value="GP_PDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03009">
        <property type="entry name" value="GDPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="SSF51695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51704">
        <property type="entry name" value="GP_PDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021922570" evidence="1">
        <location>
            <begin position="24"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="domain" description="GP-PDE" evidence="2">
        <location>
            <begin position="24"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="275" mass="30765" checksum="A88C91C3EE6BEC20" modified="2019-10-16" version="1" precursor="true">MLNGRWLLAALFVCGSLNTTLWAQMIVAHRGASYDAPENTVAAFEEAWRQQADGVEGDFYLTTDGQIVCIHDRDTQRTGGRRLKVSDSSLEQLRELEYGAWKDARFAGEPLPTFADVWKAIPAGKLFVVELKVGPEIVMPLKRQLEELNVPLDQVLIICFNSDTVARCKELLPTVRAHWLTSYKKDASSGKWRPSVDQIAQTIRDCGADGLGTQGNRQVVTPEFIAQLKSRGLEEFHVWTIDSPDDARYFQKLGAMGITTNRPALIRESLATETR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVU7</accession>
    <name>A0A518IVU7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pyridoxamine 5'-phosphate oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_32200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019595">
        <property type="entry name" value="DUF2470"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037119">
        <property type="entry name" value="Haem_oxidase_HugZ-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10615">
        <property type="entry name" value="DUF2470"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2470" evidence="1">
        <location>
            <begin position="182"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="269" mass="29749" checksum="C0B5F5B04F630613" modified="2019-10-16" version="1">MAQPRKHAYTTASEDPNPAAETTFAERARTMLSLSQVGVISTHSVHCKGFPFGSTMPYALDAIGRPLFLISAMAMHTKNLREDPRASLFVTDPSADRDPLGAGRLTLVGSAEPVPDEELDETRALYLSRHENASYYVDFADFSFWRLNPTELYFVGGFGVMGWIQADDFQHAVADPLAESATGILQHMNDDHAAAMLDIAFAEKEIVASEAKMTAVDRLGFHLRLKTPERVQSVRIGFPQEVRSSDECRQAIVAMVKQARSDKESKNEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWC7</accession>
    <name>A0A518IWC7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_33990</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021731353" evidence="1">
        <location>
            <begin position="27"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="69" mass="6925" checksum="EF4AC1FD03ABF88D" modified="2019-10-16" version="1" precursor="true">MFKLMFIGLALVGGIAVAPFAQSSAAAPCVCCGEACTCESCACDENQCACDVGGPCQCSDQCNATCCTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWM9</accession>
    <name>A0A518IWM9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_35120</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010869">
        <property type="entry name" value="DUF1501"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07394">
        <property type="entry name" value="DUF1501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="480" mass="52795" checksum="BA6632C4B4A8D804" modified="2019-10-16" version="1">MNMLPKTRRQFLQSTGMGVGSLALQWMLAQETATAKPPVLKATPHNDLLPRQTHFQPRAKAMISLFQHGGPSHMDLTDPKPELTKYDGTEYSGDIHFSFVNDASKKLLGSPFKFKAHGQCGMELSELLPHTAGVADELCLIRSMHTGANGHEVSIRYFHGGIPAVLGRPTFGSWLTYALGSETQDLPAFMVLADPGGHPVDGATNWSNGFMPSMFQGTVLRPKEPRILNLQPPSHLAGDYQRQNLDFLQELNRQHLDAHPGESDLEARIASYELAARMQTAATEALDISQETAATHKMYGLDNPKSREYGTRCLLARRLVERGVRFVQLFHSGQPWDNHSNLKGGLTSVCEKTDQPTAALVADLRQRGMLDSTLVHWGGEIGRLPVTQGQGAADKAGRDHNGQGFSIWMAGGGVRGGMTFGKTDEFGHRAVENIVTPNDFQATVMHLFGLDHEQVVFPHRNQQQIVTAHRPARVVKEVIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IX57</accession>
    <name>A0A518IX57_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_36820</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
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            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
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                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
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        <source>
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        </source>
    </evidence>
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</entry>
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    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
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                <person name="Overmann J."/>
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                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
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                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
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    </evidence>
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        <source>
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    </evidence>
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</entry>
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        <submittedName>
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                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
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                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
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        <property type="project" value="UniProtKB-KW"/>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
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    <feature type="transmembrane region" description="Helical" evidence="1">
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        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
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    </evidence>
    <sequence length="312" mass="35513" checksum="F79BCC04F09401A3" modified="2019-10-16" version="1">MQLDRTHVVVRPRSSSELCDLALLLMRQYFFPLCVAFFVGVLPFALLNALLIGWLPIESEFEGLADDETLAWRTEYVVLMASLIFLEAPLAGIFATLYIGQAVFEQRPTWRQVAQDAWATCRRWVWILGILRGPLPALLILMWCWWLGDADGLAVLFMMLILIFVCSFRAFRPHAPEILLLERCPLRSDKSGAVTFARRSHLFHTPVVGDSVNRFVTMMLLSVLLTVSLFFAMIFLQGVFAQRWSFNLVAQLVYVPVAMWIVAGYSVLFRFLCYLDNRIRLEGWDVELGLRAEVQRQFGVPESEAIAPGVGS</sequence>
</entry>
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Boedeker C."/>
                <person name="Pinto D."/>
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                <person name="Rivas-Marin E."/>
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                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 4">Mal33</strain>
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</entry>
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
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                <person name="Storesund J.E."/>
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                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
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                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
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                <person name="Spormann A.M."/>
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                <person name="Devos D.P."/>
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                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
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            <strain evidence="1 2">Mal33</strain>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="111" mass="12535" checksum="55E2A8FD4B9DEDF4" modified="2019-10-16" version="1">MSTATFDRETLAHWYAAEHLQTDPGIAKVIYLPQGAGPREIRFLEINTSIDEGPSNRPLLPIDFGVDTGQQSAHKLYVVDLTPQQWDQVLQRKLALPEGWSLDSKEEFPCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXU7</accession>
    <name>A0A518IXU7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Quaternary ammonium compound-resistance protein SugE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">sugE_2</name>
        <name evidence="6" type="ORF">Mal33_39270</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000390">
        <property type="entry name" value="Small_drug/metabolite_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045324">
        <property type="entry name" value="Small_multidrug_res"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30561">
        <property type="entry name" value="PTHR30561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00893">
        <property type="entry name" value="Multi_Drug_Res"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="29"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="59"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="84"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV57911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="105" mass="11090" checksum="0630797E5C4D43F7" modified="2019-10-16" version="1">MSWVILVIAGLLEAGWAIGLKYTEGFTKLVPSVLTIAGIIASMYLLALAARTLPIGTAYAVWVGIGTFGAIVLGMTFLGEPVNAGRIFFLILLMVSIIGLKLTAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXU9</accession>
    <name>A0A518IXU9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Methylthioribose-1-phosphate isomerase</fullName>
            <shortName evidence="2">M1Pi</shortName>
            <shortName evidence="2">MTR-1-P isomerase</shortName>
            <ecNumber evidence="2">5.3.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">S-methyl-5-thioribose-1-phosphate isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2 3" type="primary">mtnA</name>
        <name evidence="3" type="ORF">Mal33_39230</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>S-methyl-5-thio-alpha-D-ribose 1-phosphate = S-methyl-5-thio-D-ribulose 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:19989"/>
            <dbReference type="ChEBI" id="CHEBI:58533"/>
            <dbReference type="ChEBI" id="CHEBI:58548"/>
            <dbReference type="EC" id="5.3.1.23"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 1/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.23" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00904">
        <property type="reaction ID" value="UER00874"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046523">
        <property type="term" value="F:S-methyl-5-thioribose-1-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019509">
        <property type="term" value="P:L-methionine salvage from methylthioadenosine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019284">
        <property type="term" value="P:L-methionine salvage from S-adenosylmethionine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01678">
        <property type="entry name" value="Salvage_MtnA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000649">
        <property type="entry name" value="IF-2B-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005251">
        <property type="entry name" value="IF-M1Pi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042529">
        <property type="entry name" value="IF_2B-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011559">
        <property type="entry name" value="Initiation_fac_2B_a/b/d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027363">
        <property type="entry name" value="M1Pi_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01008">
        <property type="entry name" value="IF-2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00524">
        <property type="entry name" value="eIF-2B_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00512">
        <property type="entry name" value="salvage_mtnA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="1 2 3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="53"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="254"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="244"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="203"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="2">
        <location>
            <position position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="355" mass="38080" checksum="D3701C3C44CD4B4A" modified="2019-10-16" version="1">MSTPAKIEPLSWQQETSGYLRLIDQTRLPTELVEIDCRSVEQVWTAIKRLSVRGAPAIGVAAAYGVCIGAAETTRQSVDQAKQQAHAAADYLATSRPTAVNLFWALDRMRKVIDRDGFGKTDAFLEALLAEARAIHQQDRETCHAIGRHGAPLIAAAKNVLTHCNAGALATAEYGTALAVIYSAHDSGQTLHVFADETRPLLQGARLTAWELQQHGVPVTVICDSMAACVMKEGRVDAVIVGADRIAANGDACNKIGTYGLSVLAKHHNIPFYVAAPCSTFDLSLASGDLIPIEQRAAYEIAEAFGKRTVPEGVEVYNPAFDVAPAELITAIITDRGVIDPVDEANVRRVVQDAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYJ9</accession>
    <name>A0A518IYJ9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_41650</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="104" mass="11229" checksum="2238E3727D85DEC5" modified="2019-10-16" version="1">MPNHSFPNERLSVPASGRSPWLRRLLWYSGWLVWLPVAGYGISTGNLWLTMGVGGPLFLASLYFSLQTLVCPECGHAIRTVGASVSNCMQCGAAFARPKSGSDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYP4</accession>
    <name>A0A518IYP4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Carbohydrate-selective porin, OprB family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_42260</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the OprB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015288">
        <property type="term" value="F:porin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008643">
        <property type="term" value="P:carbohydrate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007049">
        <property type="entry name" value="Carb-sel_porin_OprB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038673">
        <property type="entry name" value="OprB_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04966">
        <property type="entry name" value="OprB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022260456" evidence="2">
        <location>
            <begin position="37"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU363072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="464" mass="49686" checksum="7DC915247150B2FD" modified="2019-10-16" version="1" precursor="true">MKKRTWMFAFKSTTTRFVLGFLVVSFSALVVGPSQAGAECADCDCHLAAGCDSCCDSGCDGIGGCDTSCGCLSCEGLEKCELCQSLARIRKSFADCGITMENNVTQFYMGTPSGGLNNDWGYARHGDYVMNFDFGKMGIQEGLFLKLRAEHRMGDSVSQNTGALMPATVAADLPVSDSEHVYLTNVLLTQALSENFILFAGKMDTLDGDMNAFAHGRGIRQFSNMAFVSSSIALRTVPYSTLGAGFAFLHEGSPLLTFLVLNATDTANSSGFSELFANGVTLLSELRVPTNFFGLPGHQLLGGTWSSRKYVSFGQDPRIVLPNIPVAEQDGSWSLYWNCDQYLVADSQNPKRGWGYFARAGIADQGANPIGYFLSAGLGGSSPIACRKADSFGVGYYYSGTSDKVGALLEAVAGPIGDGQGIEMFYNVALTRAITLTPDLQYLSQARENVDDAFVAGARMNIAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYR1</accession>
    <name>A0A518IYR1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_42430</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="74" mass="8477" checksum="401B535EC22AED13" modified="2019-10-16" version="1">MTVCKNVFEAILRYGHDEDFVPQDWNDFKETDAPAGSSEKIEVLRKRVELGQPLWHGSDRVDYSGLTGAIRPRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ48</accession>
    <name>A0A518IZ48_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Long-chain-fatty-acid--CoA ligase</fullName>
            <ecNumber evidence="2">6.2.1.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">lcfB_4</name>
        <name evidence="2" type="ORF">Mal33_43800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="6.2.1.3" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004467">
        <property type="term" value="F:long-chain fatty acid-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="1">
        <location>
            <begin position="21"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="553" mass="60623" checksum="05B261260DB9749B" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZB2</accession>
    <name>A0A518IZB2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FeS cluster assembly protein SufB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">sufB_1</name>
        <name evidence="3" type="ORF">Mal33_44510</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0051 (ycf24) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000825">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037284">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011542">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045595">
        <property type="entry name" value="SufBD_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43575">
        <property type="entry name" value="PTHR43575"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01458">
        <property type="entry name" value="SUFBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19295">
        <property type="entry name" value="SufBD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101960">
        <property type="entry name" value="SSF101960"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01981">
        <property type="entry name" value="sufD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SufBD_N" evidence="2">
        <location>
            <begin position="25"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="435" mass="48508" checksum="7EB3016EFFBDBA74" modified="2019-10-16" version="1">MTQTATQTKFDTEGFEAFLATKSQPQWVVDARRKAWESYQQMEWPHRRHEEWIRSDLRLFNLDKFSVPTDTPAAAETHPLLNVGVDLAGHVDTLDCHTVSESLDPELAAKGVIFGSLDRLVSEHPEIIQPLLFSAVDPTYDRFAALHAAFWSGGSILYVPRGVVIDKPLHMSSFMNDGATDLSHTLVVLEEGAEATVLQESNSFDRKAGGFHCGAIELIQRPGSHLRFVTLQDWGYKTFHFAHQQAIVDRDATLQWTISAMGAGFAKVNQQVQLVGPGADSQVNGVMFTEGRQHLAYHTLQHHSAPNCHSDFLYKSAQQDNSQTVWKGMIKVDKIAQKTDGYQRNDNLLLSGSARADSIPGLEIEADDVRCTHGSTSSQVDAEQIFYARCRGFTQKEAVRMIVTGFFQQIFDRISIESVRDALGDAIAKQVRDYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZP0</accession>
    <name>A0A518IZP0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">RNA 3'-terminal phosphate cyclase</fullName>
            <shortName evidence="8">RNA cyclase</shortName>
            <shortName evidence="8">RNA-3'-phosphate cyclase</shortName>
            <ecNumber evidence="2 8">6.5.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8 11" type="primary">rtcA</name>
        <name evidence="11" type="ORF">Mal33_45820</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 8">Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 8">
            <text>a 3'-end 3'-phospho-ribonucleotide-RNA + ATP = a 3'-end 2',3'-cyclophospho-ribonucleotide-RNA + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:23976"/>
            <dbReference type="Rhea" id="RHEA-COMP:10463"/>
            <dbReference type="Rhea" id="RHEA-COMP:10464"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:83062"/>
            <dbReference type="ChEBI" id="CHEBI:83064"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.5.1.4"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.5.1.4" evidence="2 8"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003963">
        <property type="term" value="F:RNA-3'-phosphate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.65.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00200">
        <property type="entry name" value="RTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013791">
        <property type="entry name" value="RNA3'-term_phos_cycl_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023797">
        <property type="entry name" value="RNA3'_phos_cyclase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037136">
        <property type="entry name" value="RNA3'_phos_cyclase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000228">
        <property type="entry name" value="RNA3'_term_phos_cyc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017770">
        <property type="entry name" value="RNA3'_term_phos_cyc_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013792">
        <property type="entry name" value="RNA3'P_cycl/enolpyr_Trfase_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036553">
        <property type="entry name" value="RPTC_insert"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11096">
        <property type="entry name" value="PTHR11096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11096:SF0">
        <property type="entry name" value="PTHR11096:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01137">
        <property type="entry name" value="RTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05189">
        <property type="entry name" value="RTC_insert"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005378">
        <property type="entry name" value="RNA3'_term_phos_cycl_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52913">
        <property type="entry name" value="SSF52913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55205">
        <property type="entry name" value="SSF55205"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03399">
        <property type="entry name" value="RNA_3prim_cycl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 8 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RTC" evidence="9">
        <location>
            <begin position="9"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="domain" description="RTC_insert" evidence="10">
        <location>
            <begin position="181"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-AMP-histidine intermediate" evidence="8">
        <location>
            <position position="307"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="282"/>
            <end position="286"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF05189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QDV58559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="338" mass="35967" checksum="A43E864F1DCDE9D7" modified="2019-10-16" version="1">MIEIDGSRGEGGGQILRTSLALSMVTGQPVRFVNIRAARSRPGLLRQHLTGVKAAAAVSGAKVDGDRLGSMTLTFEPSKIQAGDYHFAIGSAGSCLLVLQTILPALMIADGPSRVDLEGGTHNPFAPPFEFLELSFLPLLKEIGPEVRMTLDRPGFYPAGGGRCSAAITPAEKLQPIELIQRGTLLNREALAIVSRLPAKIAARELETAARTLGWPKSTLKVEQVTTSPGPGNALLLSVSYENVTEVVTGFGDVKVSAERVAKRAAGELKKYLNGTAPVGSHLADQLLLPLAMAGGGQFRCQQTTQHTLTNIETIKMFLDLEIDVQPQDDESVLIRVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZQ1</accession>
    <name>A0A518IZQ1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Helicase ATP-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Mal33_45870</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016818">
        <property type="term" value="F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006555">
        <property type="entry name" value="ATP-dep_Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010614">
        <property type="entry name" value="DEAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045028">
        <property type="entry name" value="DinG/Rad3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014013">
        <property type="entry name" value="Helic_SF1/SF2_ATP-bd_DinG/Rad3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006554">
        <property type="entry name" value="Helicase-like_DEXD_c2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11472">
        <property type="entry name" value="PTHR11472"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06733">
        <property type="entry name" value="DEAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13307">
        <property type="entry name" value="Helicase_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00488">
        <property type="entry name" value="DEXDc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00491">
        <property type="entry name" value="HELICc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51193">
        <property type="entry name" value="HELICASE_ATP_BIND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="5">
        <location>
            <begin position="13"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV58564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="673" mass="75608" checksum="78CCEABDEF1DCAB2" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZR0</accession>
    <name>A0A518IZR0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Inner membrane protein YbaL</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ybaL_2</name>
        <name evidence="6" type="ORF">Mal33_45950</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015299">
        <property type="term" value="F:solute:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003148">
        <property type="entry name" value="RCK_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02254">
        <property type="entry name" value="TrkA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51201">
        <property type="entry name" value="RCK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
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        <location>
            <begin position="30"/>
            <end position="48"/>
        </location>
    </feature>
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        <location>
            <begin position="60"/>
            <end position="79"/>
        </location>
    </feature>
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        <location>
            <begin position="91"/>
            <end position="112"/>
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    </feature>
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        <location>
            <begin position="118"/>
            <end position="138"/>
        </location>
    </feature>
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        </location>
    </feature>
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            <end position="201"/>
        </location>
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        <location>
            <begin position="221"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
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            <end position="261"/>
        </location>
    </feature>
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        <location>
            <begin position="273"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="298"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="333"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="domain" description="RCK N-terminal" evidence="5">
        <location>
            <begin position="407"/>
            <end position="529"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV58572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="543" mass="57831" checksum="905E8A924E00F68F" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZX6</accession>
    <name>A0A518IZX6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_46710</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="135" mass="14508" checksum="481306B3DC36BBAA" modified="2019-10-16" version="1">MQLNAQRMMTNPIRCSGRASDGPNSNSPFAIVYVEVAAAADPASEFTIDYDEPECIDQAGAKYANEEEVGYFVSGAARGVKDAAEHYEALGVSLRGLHARIVKLVAHQVDSTERAFWSAAKHATAACLVNVPRSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZZ0</accession>
    <name>A0A518IZZ0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 7">Histidinol-phosphatase</fullName>
            <shortName evidence="7">HolPase</shortName>
            <ecNumber evidence="4 7">3.1.3.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">hisK</name>
        <name evidence="9" type="ORF">Mal33_46880</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>H2O + L-histidinol phosphate = L-histidinol + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14465"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57699"/>
            <dbReference type="ChEBI" id="CHEBI:57980"/>
            <dbReference type="EC" id="3.1.3.15"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 8/9.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the PHP hydrolase family. HisK subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.15" evidence="4 7"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00013"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004401">
        <property type="term" value="F:histidinol-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010140">
        <property type="entry name" value="Histidinol_P_phosphatase_HisJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004013">
        <property type="entry name" value="PHP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016195">
        <property type="entry name" value="Pol/histidinol_Pase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21039">
        <property type="entry name" value="PTHR21039"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02811">
        <property type="entry name" value="PHP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89550">
        <property type="entry name" value="SSF89550"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01856">
        <property type="entry name" value="hisJ_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 7" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="7 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PHP" evidence="8">
        <location>
            <begin position="49"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU366003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV58664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="314" mass="35493" checksum="F468CF74AE0B8504" modified="2019-10-16" version="1">MSVCPYSAKSLRSARVAAALPAEVYGLIDTKPQSHAFHTAHDNRMLYESHSHTPLCKHAQGTPQEYAAAAHRAGMPGITITCHNPMPDKFSAHVRMEPEQWDEYKRIVAEAAEEWRGKVDVRLGLEADYYPGHVDFVRQQIADNPLSYVIGSVHPQTPEYRRDYRTDNPLQDQITYFNMLADAAETKLFDCISHPDLIKNETPEDWQTERLIDTIASVLDRIAASGTAMELNTSGRYKRITEMNPFPQMLQMIREREIPVVIGADAHVPERVGEGYPEALAILKQAGFDEVVYFVDRQPQGVSIDEALQFAWVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZZ1</accession>
    <name>A0A518IZZ1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_46820</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="321" mass="34931" checksum="136CE27AD9B2CA78" modified="2019-10-16" version="1">MNQRLIATDEAGYGPQLGPLVIASTCWDLDGSEDPAALFAGIEEGFELPGLGRVRIGDSKKLFSPKKSGGLRGLEIAMLSVAALVSSKRVDSLAKWLDLISPESSQTLAKTRWFANLNEAFPIDLDSPADMVPVRDAVSSFWQTEAVHLQAASATILPAAAFNTICDAVGNKATLLSEQTVSLVMPQILQCDAEQVEVFSDKHGGRAYYGGLLQHFFPDGQVAIELETRQVSSYRIELGSRTIRWHFTAKGDSFAPVALASMVAKYTRERLMDVFNAYWQAQVPGLRPTAGYPGDAGRFIGEIGEAITRQKLADHELVRSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J021</accession>
    <name>A0A518J021_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Extracellular serine protease</fullName>
            <ecNumber evidence="5">3.4.21.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_47130</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.4.21.-" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007154">
        <property type="term" value="P:cell communication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2030">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006644">
        <property type="entry name" value="Cadg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015919">
        <property type="entry name" value="Cadherin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038081">
        <property type="entry name" value="CalX-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003644">
        <property type="entry name" value="Calx_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002105">
        <property type="entry name" value="Dockerin_1_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036439">
        <property type="entry name" value="Dockerin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025592">
        <property type="entry name" value="DUF4347"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033764">
        <property type="entry name" value="Sdr_B"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03160">
        <property type="entry name" value="Calx-beta"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00404">
        <property type="entry name" value="Dockerin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14252">
        <property type="entry name" value="DUF4347"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17210">
        <property type="entry name" value="SdrD_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00736">
        <property type="entry name" value="CADG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141072">
        <property type="entry name" value="SSF141072"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49313">
        <property type="entry name" value="SSF49313"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="CADG" evidence="4">
        <location>
            <begin position="2504"/>
            <end position="2605"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="2708"/>
            <end position="2746"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="2710"/>
            <end position="2725"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV58689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="2760" mass="277669" checksum="D16CDD85A9FB7DE7" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J061</accession>
    <name>A0A518J061_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_47090</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="282" mass="29896" checksum="17E3811564CAA669" modified="2019-10-16" version="1">MSKIIAAMLISIALVAGLVGWLIVGDGVSPRTVSSAAKTPGGGSIDSPESKEDLRIYCAASNLAVMERIRQDYEQSTGTRISVQYGPSQSLLAQLQLTQTGDLYLPADDSYLVLAEDAGLLSLTLPIATMQVGLAVKRGNPKRIADFPALLTNEIRVVQANPDAAAVGMLTRACLLPSGKWSRLADATTAFRGTVIEVANDVHVGAADVGIVYDAVLHSYPDLEFVAIEALRPAKAQVAIGILKSSRTPGQALDFARYLTAPDRGLKVYAEHGFHVAEQVLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0F0</accession>
    <name>A0A518J0F0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ribonuclease Z</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_48330</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12706">
        <property type="entry name" value="Lactamase_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="24"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="254" mass="27958" checksum="51C6DBCDDDD8F2DF" modified="2019-10-16" version="1">MVYSASMKLHCLGTAGYHPSETRQTSCYFLPESGIVLDAGSGLFRLPSLIQTDHLDILLSHSHLDHICGLTFLLSVLYQHPVQRVRVWGDEAKLTAIKKHLFCESIFPVPLDVQWNRIVPGEAFSLGNDANVVPFALPHPGGSIGFRIDWPSASMAYVTDTTADPKADYVPIARGVDLLLHECNFRTSQDEWAIKTGHSSTRRVAETAAAIDAKQTWLVHLNPLETTDDPVGIADAKPYLSKIGVAQDLQVIDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0F1</accession>
    <name>A0A518J0F1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">Argininosuccinate lyase</fullName>
            <shortName evidence="5">ASAL</shortName>
            <ecNumber evidence="3 5">4.3.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Arginosuccinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">argH</name>
        <name evidence="8" type="ORF">Mal33_48370</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>2-(N(omega)-L-arginino)succinate = fumarate + L-arginine</text>
            <dbReference type="Rhea" id="RHEA:24020"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:32682"/>
            <dbReference type="ChEBI" id="CHEBI:57472"/>
            <dbReference type="EC" id="4.3.2.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 5">Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 3/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.3.2.1" evidence="3 5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00114"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004056">
        <property type="term" value="F:argininosuccinate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042450">
        <property type="term" value="P:arginine biosynthetic process via ornithine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01359">
        <property type="entry name" value="Argininosuccinate_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00006">
        <property type="entry name" value="Arg_succ_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029419">
        <property type="entry name" value="Arg_succ_lyase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009049">
        <property type="entry name" value="Argininosuccinate_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020557">
        <property type="entry name" value="Fumarate_lyase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000362">
        <property type="entry name" value="Fumarate_lyase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022761">
        <property type="entry name" value="Fumarate_lyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43814">
        <property type="entry name" value="PTHR43814"/>
        <property type="match status" value="1"/>
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        </source>
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        <source>
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        <source>
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        <source>
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        <source>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF14698"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="QDV58812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="458" mass="51041" checksum="8BDE2013AF0C57B9" modified="2019-10-16" version="1">MASPSRSGVFDAASDSRLEQFCESISFDRRLYEVDIEGSSAHAEMLAVQGLISGKECDQILEALAAIRVELDEDTLPMRTELEDVHMHVEQALIDRLGDVGRKLHTARSRNDQVSTDFRLWIRGQLDLVDGLLADLQRAFLGRCEGDFDVILPAYTHLQRAQPVLASHYWLAYIEKLARDRQRIADCRSRVNICSLGVAAVAGTSMDIDRKLTAEKLGFDDVTRNSLDTSSDRDFVVEAAFVLTMIAQHLSGWSEEWILWSTEEFGFLKIPHAFCTGSSIMPQKVNPDVLELTRGKTARVVGNLQTLLVLIKGLPLAYNRDLQEDKPPLFDSFDTVIACLQLAIPIVSGSTLQRDRIASRLEHGYLDATTLMEYLMKKGLPQRTAHHLVGSLVGEAMKRKIPLSEMPLDAMIEAGVSVDNSIFDVLGTANAVRAYVSFGSSAPEQVRQQMQYWKTLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0N1</accession>
    <name>A0A518J0N1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_49310</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
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            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="213" mass="23001" checksum="E23C3281C017F55A" modified="2019-10-16" version="1">MSYWRTPNSNQRARAFRGIERLESRSLMAGLVNVCDTMMKPPTQPGAVVAGVQSRADLDQSDLVTFESQKPAAKAARAPKAEPCCDDKAIWGSDCDWLDFQGDLDLGQPKSDGNDCDCECDDPNHHDDSGDEPLVPSESQPDTSFIGSTEDASTAELDRTNDPAPGPMFGPIYARPNATSSTPANPAANRASANSVAFRNFRNPAQRLLLGER</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0Q5</accession>
    <name>A0A518J0Q5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Multidrug efflux system subunit MdtC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Mal33_49390</name>
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    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
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            <taxon>Planctomycetia</taxon>
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            <taxon>Rosistilla</taxon>
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    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004869">
        <property type="entry name" value="MMPL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000731">
        <property type="entry name" value="SSD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03176">
        <property type="entry name" value="MMPL"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50156">
        <property type="entry name" value="SSD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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            <end position="357"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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        </location>
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    <feature type="transmembrane region" description="Helical" evidence="6">
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            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="605"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="638"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="664"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="706"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="737"/>
            <end position="761"/>
        </location>
    </feature>
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        <location>
            <begin position="276"/>
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        </location>
    </feature>
    <feature type="domain" description="SSD" evidence="7">
        <location>
            <begin position="674"/>
            <end position="763"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV58914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="769" mass="83657" checksum="A288D487A4E15564" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0S5</accession>
    <name>A0A518J0S5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Inner spore coat protein H</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">cotH</name>
        <name evidence="3" type="ORF">Mal33_49630</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
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                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014867">
        <property type="entry name" value="Spore_coat_CotH_CotH2/3/7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40050">
        <property type="entry name" value="PTHR40050"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08757">
        <property type="entry name" value="CotH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0167">Capsid protein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0946">Virion</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021751929" evidence="2">
        <location>
            <begin position="19"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="392"/>
            <end position="482"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="580" mass="63011" checksum="EBEC1F46F1BC6E59" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J121</accession>
    <name>A0A518J121_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidyl-prolyl cis-trans isomerase</fullName>
            <ecNumber evidence="4">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">fkbP</name>
        <name evidence="6" type="ORF">Mal33_50680</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 3 4">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the FKBP-type PPIase family.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061077">
        <property type="term" value="P:chaperone-mediated protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000413">
        <property type="term" value="P:protein peptidyl-prolyl isomerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044609">
        <property type="entry name" value="FKBP2/11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45779">
        <property type="entry name" value="PTHR45779"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase FKBP-type" evidence="5">
        <location>
            <begin position="23"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV59043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="131" mass="14724" checksum="F91E7FA392E8D7DC" modified="2019-10-16" version="1">MKIPRGLKLEDTTVGTGRHAVPGDTVRFEYECRLNRGDLISDSTDFGPYQYRLGCRDCSPGVEYGLMGMRTGGVRQIKLPPHLTYVDRQINPEIPKDAVVRYTLRLVEIVDPPWDPDMATRLDCSGLRISG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J123</accession>
    <name>A0A518J123_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_50620</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="175" mass="20080" checksum="D7709B0517716409" modified="2019-10-16" version="1">MLTAVVGATTNLIVAFYRESLPIAWQTFTYAKAESLQRDGATVLFFGNPTYHPGGQLVRQRLDESPLRLASHRHVFVPLMRTYPNWNDPEIRNVWKRFGHTKRPVMLIFKPDGSIAQLEPLDTKAIEQQFTAQSPIPIIPSLAWGVTIVAFIAWRHSRNHKTEPKNAHERRIRVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1B8</accession>
    <name>A0A518J1B8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Serine/threonine-protein kinase PrkC</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">prkC_12</name>
        <name evidence="2" type="ORF">Mal33_51540</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18808">
        <property type="entry name" value="SF1_C_Upf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045055">
        <property type="entry name" value="DNA2/NAM7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025103">
        <property type="entry name" value="DUF4011"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887">
        <property type="entry name" value="PTHR10887"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13195">
        <property type="entry name" value="DUF4011"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="91"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="2081" mass="232390" checksum="339610B4FB295FC4" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1D4</accession>
    <name>A0A518J1D4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_51780</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="51" mass="5804" checksum="625CABACC20A46EC" modified="2019-10-16" version="1">MTTSTTEATATHLPEHRFDRSTLRQLTFEEGEEFPNLRVHTNDKGLSRASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1K3</accession>
    <name>A0A518J1K3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Planctomycete cytochrome C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_52520</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
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                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxoprolinase family.</text>
    </comment>
    <dbReference type="EC" id="6.4.1.8" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008040">
        <property type="entry name" value="Hydant_A_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002821">
        <property type="entry name" value="Hydantoinase_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003692">
        <property type="entry name" value="Hydantoinase_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045079">
        <property type="entry name" value="Oxoprolinase_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11365">
        <property type="entry name" value="PTHR11365"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05378">
        <property type="entry name" value="Hydant_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01968">
        <property type="entry name" value="Hydantoinase_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02538">
        <property type="entry name" value="Hydantoinase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hydant_A_N" evidence="4">
        <location>
            <begin position="137"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="Hydantoinase_A" evidence="2">
        <location>
            <begin position="274"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="domain" description="Hydantoinase_B" evidence="3">
        <location>
            <begin position="757"/>
            <end position="1276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV59495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1280" mass="136164" checksum="080CF1B2358D1971" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J2F0</accession>
    <name>A0A518J2F0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_55480</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="246" mass="26487" checksum="DA3517BCCC14DA0F" modified="2019-10-16" version="1">MWISKTKSPYLALLLATMFGFVMGVASSGIADEVDEPKELSKVEAAADEKSDSKQEAKPESKPEPSEADSQPHELSTAPLDYPIYPEDRPMWVDQPDKNGDDWAELVVQSVPSLSADSSRESLLQQQKIALIAYIDQALGFPGAGEKIAVPAEQIASGLVDPDRTYNGKLTTSTGEMFQHASVLVLDDDFHSEITQQWQALEVGQRLKGLGVLAALALVGLSGLTVLLKSISPRSKVGHDDKTALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J2G0</accession>
    <name>A0A518J2G0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cysteine desulfurase</fullName>
            <ecNumber evidence="4">2.8.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">nifS</name>
        <name evidence="9" type="ORF">Mal33_55630</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[sulfur carrier]-H + L-cysteine = [sulfur carrier]-SH + L-alanine</text>
            <dbReference type="Rhea" id="RHEA:43892"/>
            <dbReference type="Rhea" id="RHEA-COMP:14737"/>
            <dbReference type="Rhea" id="RHEA-COMP:14739"/>
            <dbReference type="ChEBI" id="CHEBI:29917"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:64428"/>
            <dbReference type="EC" id="2.8.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.7" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031071">
        <property type="term" value="F:cysteine desulfurase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044571">
        <property type="term" value="P:[2Fe-2S] cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010240">
        <property type="entry name" value="Cys_deSase_IscS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016454">
        <property type="entry name" value="Cysteine_dSase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11601:SF34">
        <property type="entry name" value="PTHR11601:SF34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005572">
        <property type="entry name" value="NifS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_5" evidence="8">
        <location>
            <begin position="2"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV59528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="381" mass="40499" checksum="41BCB40371D9C8B5" modified="2019-10-16" version="1">MIYLDNNATTAITPEVLDAMRADWMLGPANPSAQHRIGRSAKLRLEDACDAMLDCLSASEHRFLLTSGGTEANNWVIGNLGQGDGPIIVSQIEHPSILAAARAAEARGIPVRYLPVDANGIVDLPLLQTWLAETPKPRLVSIMAANNETGVIQTIAPLAACCNDAGVPFHSDLSQMLGKLPVDIDQMGIAAATIAAHKFHGPVGVGGLILRRNAPISPLLVGGAQQLEHRAGTEPTALVVGMMTAIQQCLNDLSTTQTAMRQRRDALEAGLRQQIPDLVVHSAAVDRLPQTTCFSIPNIDRQALLMRLDFESVACSTGSACASGSSEPSHVLQAMGADSSLLSSSIRLSGSIFTTDSEIDTAVSRIVRCCNKLRNYQDVEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J2G1</accession>
    <name>A0A518J2G1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Acyl carrier protein</fullName>
            <shortName evidence="7">ACP</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">acpP_3</name>
        <name evidence="7" type="synonym">acpP</name>
        <name evidence="10" type="ORF">Mal33_55550</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Carrier of the growing fatty acid chain in fatty acid biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="7">4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the acyl carrier protein (ACP) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="term" value="F:acyl carrier activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Acyl_carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003231">
        <property type="entry name" value="Acyl_carrier"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
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        <property type="entry name" value="PTHR20863"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="3 7" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="5"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="7 8">
        <location>
            <position position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV59520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="128" mass="14320" checksum="CB80BD8AF769CCD4" modified="2019-10-16" version="1">MPTQDEVYEKVQAALVDALGVDDDEVTPEATMVGDLGAESIDFLDIVFKLEKAFDIQIPREELFPEDILTNSEYVKDGKVTEDGLVELKKRMSWADLSKFEKNPRVQDFGDLLTVNDLCSYVNSKVGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J2G7</accession>
    <name>A0A518J2G7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_55620</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="236" mass="25851" checksum="29C2CAF0F14DD19F" modified="2019-10-16" version="1">MTASPSPVSKSRSPIVWIITAIVLLVVGLFGCLILWLASGVSGREFAPSHFQTRTFNVASVPWIGFQIGSLDHSSVNDATSQYLIANKLINVPATPPKRWDLLEIHRNVSLPHDADASVLTLYLTGRGSHGVDWEQWSKDHPAAAAVFWPFVQQLAIDQLYLMLPQAFDLARQQTDPVELQQALDDYFVAEFPAFAADLAHAGREAEAIAALESAIGRYPQQASFSAALDDLQSQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IM37</accession>
    <name>A0A518IM37_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Type II secretion system protein D</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">pulD_1</name>
        <name evidence="7" type="ORF">Mal33_01050</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bacterial secretin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.120">
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001775">
        <property type="entry name" value="GspD/PilQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005644">
        <property type="entry name" value="NolW-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038591">
        <property type="entry name" value="NolW-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004846">
        <property type="entry name" value="T2SS/T3SS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00263">
        <property type="entry name" value="Secretin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03958">
        <property type="entry name" value="Secretin_N"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00811">
        <property type="entry name" value="BCTERIALGSPD"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021892166" evidence="5">
        <location>
            <begin position="22"/>
            <end position="1269"/>
        </location>
    </feature>
    <feature type="domain" description="Secretin_N" evidence="6">
        <location>
            <begin position="389"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="domain" description="Secretin_N" evidence="6">
        <location>
            <begin position="462"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="domain" description="Secretin_N" evidence="6">
        <location>
            <begin position="542"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="domain" description="Secretin_N" evidence="6">
        <location>
            <begin position="641"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="domain" description="Secretin_N" evidence="6">
        <location>
            <begin position="732"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="318"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1177"/>
            <end position="1196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV54159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1269" mass="136220" checksum="87E3771687EB04F5" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IM83</accession>
    <name>A0A518IM83_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Serine protease HtrA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">htrA_1</name>
        <name evidence="3" type="ORF">Mal33_01450</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001940">
        <property type="entry name" value="Peptidase_S1C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033116">
        <property type="entry name" value="TRYPSIN_SER"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00834">
        <property type="entry name" value="PROTEASES2C"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00135">
        <property type="entry name" value="TRYPSIN_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022124662" evidence="2">
        <location>
            <begin position="27"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="462"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="500" mass="54062" checksum="91CDADD7FEBE75CB" modified="2019-10-16" version="1" precursor="true">MKKISWKKNLALMSLAALMATSTTNATEETGKPVSLPVHADQALAALQPGSGPIDLNAKPIPKGLGALLGQASRGPAASVFPKIAPSVVVVRAGGGYGTGFVVDADGWILTNNHVIESAGIDIGTASRYAFIHFGDLEDGMMTLNQQASPALVYAASPEKDLALLKLLAVPEGRDLKPIAFAAKNATPGTDCITIGHPKRGVFWSVRSGEVVGIAKYPHDMIDTVMTQMVMASDAKQSFAKSLSESRPRKALLSTCGINPGDSGGPLLNNDGELVAVNFAIPKSEKDSQVNLDKFSYHVHLDEVKEFTAIRPEKSEVFQPNYWPPAATSSFLDVDDDDVYETWRFSIDEETPFTGVVVDLDSDTPANFIEDYKADKQDRNQFECEFALALIPNNRVFYDRDNDGEFDLILTDVDENGFSDLTIAKNSNGWEKIDSKEQRMFDPTVFQDAKLQERFKVLVMSQTKNPEGMAPDGLSPEEAKPEAEASPADSAPADAADSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMA7</accession>
    <name>A0A518IMA7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_01650</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="50" mass="5473" checksum="3CD0D1368B387A44" modified="2019-10-16" version="1">MWPGACATRLYAIAALQLMRRGGFVRTLDIAIRRCLGLAPPGFTRSPLRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMN4</accession>
    <name>A0A518IMN4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">tRNA-specific 2-thiouridylase MnmA</fullName>
            <ecNumber evidence="7">2.8.1.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 8" type="primary">mnmA</name>
        <name evidence="8" type="ORF">Mal33_02860</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>AH2 + ATP + S-sulfanyl-L-cysteinyl-[protein] + uridine(34) in tRNA = 2-thiouridine(34) in tRNA + A + AMP + diphosphate + H(+) + L-cysteinyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:47032"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11726"/>
            <dbReference type="Rhea" id="RHEA-COMP:11727"/>
            <dbReference type="Rhea" id="RHEA-COMP:11728"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61963"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:87170"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.8.1.13"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the MnmA/TRMU family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.13" evidence="7"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016783">
        <property type="term" value="F:sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01998">
        <property type="entry name" value="tRNA_Me_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00144">
        <property type="entry name" value="tRNA_thiouridyl_MnmA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023382">
        <property type="entry name" value="Adenine_a_hdrlase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004506">
        <property type="entry name" value="tRNA-specific_2-thiouridylase"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00420">
        <property type="entry name" value="trmU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 7 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="2 7" id="KW-0820">tRNA-binding</keyword>
    <feature type="region of interest" description="Interaction with tRNA" evidence="7">
        <location>
            <begin position="159"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Interaction with tRNA" evidence="7">
        <location>
            <begin position="314"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="7">
        <location>
            <position position="112"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine persulfide intermediate" evidence="7">
        <location>
            <position position="209"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="26"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Interaction with tRNA" evidence="7">
        <location>
            <position position="137"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with tRNA" evidence="7">
        <location>
            <position position="347"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Alternate" evidence="7">
        <location>
            <begin position="112"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV54333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="372" mass="40297" checksum="B16C1A754D74A1C4" modified="2019-10-16" version="1">MSGGVDSSVAAHLLLQQGHEVVGVFMRHGEESAEVCRAPDGSESPVLPIVQGRADHKQGCCSASDAADARRVSDRLGIPFYALNLKQDFRRIIDYFVDEYSQGRTPNPCVQCNNWIKFGRLFEYADSIDAQYVATGHYAQLSEEADGSFALRRGVDDRKDQSYVLFGIGQHLLSRMLLPVGGYDKPWIRQQAEAIGLRVAGKPDSQEICFVTSGHHGQFVRDRSGGGNTAGQIVTTAGDVVGEHPGIEAFTIGQRKGLGVAMGEPYFVVRIEPDTHRVVIGQKADLARDGLIAHEANWLIDPPAETFSCSVQIRYNSPPQAAQVTPQGTDRFDVLFDEPVDGVAPGQAAVIYDGDRVLGGGWIHSSTSTSAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMR7</accession>
    <name>A0A518IMR7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_03260</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046031">
        <property type="entry name" value="DUF5989"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19451">
        <property type="entry name" value="DUF5989"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="65" mass="7390" checksum="325CD89D4C642419" modified="2019-10-16" version="1">MEDQDDKFAEIANASHEQSFLSELVEFLRFNKKWWLAPILVALLLLGALLMLSSTAAAPFIYTLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IN27</accession>
    <name>A0A518IN27_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">3-oxoacyl-[acyl-carrier-protein] synthase 2</fullName>
            <ecNumber evidence="4">2.3.1.179</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">fabF_2</name>
        <name evidence="4" type="ORF">Mal33_04440</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.179" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00834">
        <property type="entry name" value="KAS_I_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000794">
        <property type="entry name" value="Beta-ketoacyl_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11712">
        <property type="entry name" value="PTHR11712"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PKS_KS" evidence="3">
        <location>
            <begin position="10"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV54490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="436" mass="45599" checksum="8E47603FA641993A" modified="2019-10-16" version="1">MRDSVSPRRVVITGVGLISPLGNQVEAVWEALRDRKSGVDLLQALPSDAMSISCGAEARDFTGSISEFGPLDKQLQRAIKKGLKLMCREIEMGVAAAQLALHDSGLSSDVRDPDRTGVLYGSDYIMTLPEEFAAGIRKCQDAEGRFQFERWSELGLPEVNPLWLLKYLPNMPASHIAIYNDLRGANNSLTLREASPGAAIGEAVSTISRGIVDAMVVGATGTRINPFRTLHVVMQEVLAGGSENPAGLSRPFDKDRTGSVLGEGAGAFILEELEFAKARGAEILGEVVGFGSGTAGATAGPQFIQTAMANALRGAMRNSDTTVGHVNAHGIGTPDGDIQEAAAIVEVLGPDTPPVVAAKGNFGNLGAGGGMVEAIASIKALSEGSLWPTLNYETPDADCPINVVSSNDVPAGDNFVSLNVSPQGQATAFRIAKFAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IN45</accession>
    <name>A0A518IN45_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_04560</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011447">
        <property type="entry name" value="DUF1552"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07586">
        <property type="entry name" value="HXXSHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="458" mass="50455" checksum="B34433D291F8FF79" modified="2019-10-16" version="1">MSNYLSQSWLIDRRHALRAMGSLISLPLLECMLPLRAAEKETAAPRRSAFIYLANGVHSLNYQITTPGKDYQLSRSLMPLEKHRQVITPISGLHHPGALSHHHNCISVWLTGGKLGPSDRNTISVDQKMAEVTAQHTRVASMEVAITQDSLAWTADGVRLPAMRRCSEIFASMFEEPKGGKAAQRRALRRKGSVLDANLAEVRRLEKKMGSADKGRMDQYLSSIREAEIRTRRADAWLDTPLPVVSDADRKRTNRDIATTMAGDYFRTVYDLMVLAFQTDVTRVATFSMGGEGDAIAIPEIGITESRHQLSHHGGDAGYMEKLTMYDTFAVEQFSYFLTRLAETNDLNGKPLLDSTMALFGSGMCYGHSHGNANLPLVLAGGSDLGLKHGSHLDFNQSADGFKGYALGADGALTTAHYQLCSRPANPNAHMSNLLLMMAQRMGVEIDQFGDSNKMIEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IN49</accession>
    <name>A0A518IN49_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">HTH-type transcriptional repressor CsiR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">csiR_1</name>
        <name evidence="5" type="ORF">Mal33_04580</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011711">
        <property type="entry name" value="GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008920">
        <property type="entry name" value="TF_FadR/GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07729">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00895">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48008">
        <property type="entry name" value="SSF48008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="4">
        <location>
            <begin position="5"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV54504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="226" mass="25453" checksum="E15C81C35D7E1022" modified="2019-10-16" version="1">MFERKCMSDVIRDRIAGRIYDGSLQPGERLRELAIAEEFGTSQTPVREALRELEALRLVHSEAYKGTRVREITAREMTEVYLVRAILEQRAAELAGARLENNVEPLNQAVDRICDSAADGDVDGYARHNLDFHRQIVVAADNMVLLQTWDSLRFEAKIRINLIRKMPSIVERAAEHRPIVAALRLGDGDAAGRLLREHSESFAAVWAEEAAAQLKTQEMEAQETSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IN62</accession>
    <name>A0A518IN62_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_04750</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021259">
        <property type="entry name" value="DUF2817"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10994">
        <property type="entry name" value="DUF2817"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="358" mass="39538" checksum="3508FFE04EAC976C" modified="2019-10-16" version="1">MTEDYFSSSYLQSRERFRIAADAIGASCDSYQVSGAGEGGLTIDVATLGPADAPAVVVSSGVHGVEGFFGSAVQLAMLDRFSRQPPDRGLRFVLIHAINPFGFDQLRRFDEANIDLNRNFLIDPQTYKGSPAGYGALDRFLNPASPATRWELPFHLQAMALIARHGMPTLKAAVARGQYEYSSGLFFGGSQPAASMLVVRDHCARWIGDAPSVVHIDLHSGLGRFGECQLMPVVSDAAPASAFIDGFPDRSLEFEATHQRTAYTVCGGMGQWFVDRFSDRPYRFALAEFGTYGPLRVLAALRRENRFHFQGPRDTEAQRRAKAELLECFCPRSAAWRRRVIDASLSIVDQASRWSQRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IN83</accession>
    <name>A0A518IN83_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_05090</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010869">
        <property type="entry name" value="DUF1501"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07394">
        <property type="entry name" value="DUF1501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="433" mass="47005" checksum="AEB4D6C8EF63CC99" modified="2019-10-16" version="1">MFNSQWTTPAGMTRRHFMNHMAGASAAMAGTAFTLGQTLKANADVLKKNRKSAILLWMGGGPSTIDLWDLKPGAPTGGPFKPISTSGDVQICEHMPLMAKQMHNMAVIRSMSTREADHDRGRYYMHTGFVPNPNIEHPSYGSVLAHELIGQRPELEIPPFVTIGGGSAGPGFLGMAWAPFAVTSNGQIRNLQMRMEQQRLMQRMAALDLIEKDFVKKNRGTAAEDHQKVLKKTFDLMSSEQMQAFKVAEEPEAVKERYGATGMGMGGGGFGQGCLLARRLVEAGVPFVEVDLGGWDSHSDIFNTLTNRHLPALDKAMSALTEDLEQRGMLQDTAIIWMGEFGRTPRINQNAGRDHFARAWSVVVGGAGMKGGIAIGETNSDGTAVETEPYSSEDVMTSVCKALGISPDTTYTANNRRPMKIAGGGKIIKDLFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INB3</accession>
    <name>A0A518INB3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_05440</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010985">
        <property type="entry name" value="Ribbon_hlx_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014795">
        <property type="entry name" value="Vibrio_phage_ICP1_Orf50"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08681">
        <property type="entry name" value="DUF1778"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47598">
        <property type="entry name" value="SSF47598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="89" mass="9709" checksum="1D9149E246A23580" modified="2019-10-16" version="1">MQKTSSLMVRLDEQSKATLSAAAELRRISVSDYVRSVVVGQAERELAAAEAQTVAMTAEEQLQFWNALAKPPKLSKAQKELGAMMRGEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INE5</accession>
    <name>A0A518INE5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transposase DDE domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_03070</name>
        <name evidence="4" type="ORF">Mal33_04610</name>
        <name evidence="5" type="ORF">Mal33_05610</name>
        <name evidence="6" type="ORF">Mal33_18320</name>
        <name evidence="7" type="ORF">Mal33_18340</name>
        <name evidence="8" type="ORF">Mal33_19330</name>
        <name evidence="9" type="ORF">Mal33_31720</name>
        <name evidence="10" type="ORF">Mal33_33470</name>
        <name evidence="11" type="ORF">Mal33_51570</name>
    </gene>
    <organism evidence="5 12">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 12" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 12">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002559">
        <property type="entry name" value="Transposase_11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01609">
        <property type="entry name" value="DDE_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_1" evidence="2">
        <location>
            <begin position="132"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="422"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="436"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV54507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV54606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV55853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV55855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV55954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV57171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV57343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QDV59131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="463" mass="52684" checksum="502B22D11D4FB088" modified="2019-10-16" version="1">MTTPENESDAEAPFCRAKALLSELLGLPQIQAAFEGQEASHAQRVYTQAPTLWLLVMQRLGGGLTLDQVVKDLIQNHSDILPENRRVTQGRLSENNSAYNKARQRLPVQRIEEFSHRVCDHLARRAEPAFLDHRVFILDGTTVTLPPTPGLKKAFPPARNQRGESVWPVACLMVAHEMQTGCALAPQIDPMYGPNNSSEPKQAKKIIDRLPENSIVLADSGFGIFSVAFHCQLRAKPFILRLTKQRYKAYIKNATLIEDAAGYRTYHLIWKPTAQERKKHPEFPVDAAVEAFIHQVDLQNEQTLELVTSIEVDALSVGELYRRRYDVEFDIRDLKVTMDTENIRAKSVDTFMKELLGSVIAYNLVTQLRKQAAKLINVPPRRLSFSGVWTTFRYDLLYKECGTLQEWNHAFQRALVSASGRKLPNRKEPRSYPRLAHTRRQKSTKFQKSLRKSKRKGPAPPPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INM3</accession>
    <name>A0A518INM3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_06500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="247" mass="28547" checksum="6B52987C560528D8" modified="2019-10-16" version="1">MMDESPWIDEFEAAWQQRRWADVDRILRDPELPIDDAAELAMIDLEYRWQYPLPKEASRQAAVQNSPQVEDYCRLRPALAEDPQRLLELISEEYRVRLKWDHPPTPEDLSARFEAFPRQAIEKMICRVEQEVPHLWLAVVRGDTELVRLRFHRPLEIGRQSIGQPPPFGEVLADGNRKLVIAVIDNLQVSRRQLRISRCSVGARLENLSSQVAVQTGFRTRLMPGETVELAVPLTLTIGDLRFCLSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP51</accession>
    <name>A0A518IP51_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 13 15">tRNA (guanine-N(1)-)-methyltransferase</fullName>
            <ecNumber evidence="6 13 15">2.1.1.228</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">M1G-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">tRNA [GM37] methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13 17" type="primary">trmD</name>
        <name evidence="17" type="ORF">Mal33_08360</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 13 15">Specifically methylates guanosine-37 in various tRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13 15">
            <text>guanosine(37) in tRNA + S-adenosyl-L-methionine = H(+) + N(1)-methylguanosine(37) in tRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:36899"/>
            <dbReference type="Rhea" id="RHEA-COMP:10145"/>
            <dbReference type="Rhea" id="RHEA-COMP:10147"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:73542"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="EC" id="2.1.1.228"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5 13 15">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 13 15">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 13 15">Belongs to the RNA methyltransferase TrmD family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.228" evidence="6 13 15"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052906">
        <property type="term" value="F:tRNA (guanine(37)-N(1))-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd18080">
        <property type="entry name" value="TrmD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1270.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00605">
        <property type="entry name" value="TrmD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002649">
        <property type="entry name" value="tRNA_m1G_MeTrfase_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023148">
        <property type="entry name" value="tRNA_m1G_MeTrfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016009">
        <property type="entry name" value="tRNA_MeTrfase_TRMD/TRM10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46417">
        <property type="entry name" value="PTHR46417"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01746">
        <property type="entry name" value="tRNA_m1G_MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000386">
        <property type="entry name" value="tRNA_mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00088">
        <property type="entry name" value="trmD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 13 15" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 13 15" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 13 14" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="10 13 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="12 13 15" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="tRNA_m1G_MT" evidence="16">
        <location>
            <begin position="23"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="13 14">
        <location>
            <begin position="134"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13 14">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00014679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR000386-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU003464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF01746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="QDV54871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="227" mass="25821" checksum="78135B2B648C9B7C" modified="2019-10-16" version="1">MRFDVVTLFPAIFDGYLTQSLLNKAIENQLVQIHCHNLRDWSTDEKHHKIDDRPFGGGPGMLIQAPPVVDCVEEIESKEARPARRILLSPQGRRFDQQLAEELATEPRLMLLCGRYEGFDQRVIDILEPEELSVGDFVLNGGEVAAMVVIDAVVRLLPGVLGDEFSSFDDSFSRGNRMLEFPQYTRPREFRGHEVPEVLLGGNHQQIAAWRADQIQKRTAERRSDLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP61</accession>
    <name>A0A518IP61_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">30S ribosomal protein S16</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3 5" type="primary">rpsP</name>
        <name evidence="5" type="ORF">Mal33_08350</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the bacterial ribosomal protein bS16 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00385">
        <property type="entry name" value="Ribosomal_S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000307">
        <property type="entry name" value="Ribosomal_S16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023803">
        <property type="entry name" value="Ribosomal_S16_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12919">
        <property type="entry name" value="PTHR12919"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00886">
        <property type="entry name" value="Ribosomal_S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54565">
        <property type="entry name" value="SSF54565"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00002">
        <property type="entry name" value="S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="91"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV54870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="129" mass="14257" checksum="754A5AAC8BE76BF0" modified="2019-10-16" version="1">MAVRIRMKKMGRAHRPFYRLCAVDQRNPRDGKVIEELGYYDTSVPETDARAILKGERINYWLGVGAQASDKCQILIKKYGAEGTHLEKQREALQRMQAGRPVPAPKPAKPKAEAEAPAAEAAPAEAASE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP64</accession>
    <name>A0A518IP64_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 12">Pyruvate kinase</fullName>
            <ecNumber evidence="4 12">2.7.1.40</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">pyk</name>
        <name evidence="15" type="ORF">Mal33_08330</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + pyruvate = ADP + H(+) + phosphoenolpyruvate</text>
            <dbReference type="Rhea" id="RHEA:18157"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.40"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 12">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 5/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the pyruvate kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.40" evidence="4 12"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00188"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030955">
        <property type="term" value="F:potassium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004743">
        <property type="term" value="F:pyruvate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
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        <source>
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    </evidence>
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        <source>
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        <source>
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        </source>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF02887"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="QDV54868.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="536" mass="58001" checksum="14EC593FDE4BB043" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP85</accession>
    <name>A0A518IP85_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytochrome c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Mal33_08650</name>
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    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <location>
            <begin position="1"/>
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        </location>
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        </location>
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        <source>
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        <source>
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        </source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="QDV54900.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="470" mass="52929" checksum="D28BA46D9DDC47BC" modified="2019-10-16" version="1" precursor="true">MQVKQLFILIVALSLTAADGKEPLAADASPAQDPAAAEAVPTDPAVAERGYRFLTEKAYLSPDFHQSDFDALWEVWPPELRAQAADATVEQRRQMAFERYGLTKRPNDDSGRPLQYVVDDAGNWTMNCFSCHGGTVYGQVFPGAPNNAFGLQTLSEEMRKVKFRSGKRLTRMELGSAVLPLGTTHGTSNAVIFGIALMNYRDKDLNLVLDRQPPPMLHHDLDAPPWWNLHKKDFVYIDGFARLSHRGLMQFMLSRGNGPERFREWEPDFKDVLTYVQGLRPPKYQGSIDDKLAQQGRVVFNQTCAECHGTYGDGGEYPNRRIALDDIGTDPIRLLALPTIAKEKYVESWFSDYGRDGSYAESNGYVAPPLDGIWASAPYLHNGSVPTLWHLLHPEQRPKIWRRTATEIDAQRVGLQIEQVDRVPLTQTDWAIRRTYFDTQQVGKSASGHDYPSKLSEAERTAVLEYLKTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP96</accession>
    <name>A0A518IP96_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_08820</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
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    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="25"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="300" mass="33339" checksum="694315847F3F5ABA" modified="2019-10-16" version="1">MTTNEKTEAALSDIEARQRQIAADKAAADKEQDVIDRQIAQLREQAAANAKAQRELDEQRERLEREAIDRQRELRPDHVDRDVAASVATDLLDAFEAVHVTEAEMVGPDRRAERLWDAIDDARCRLLTDDIAEDARPVVLAIEGVIEACDFFESFRRPEFGAARAADGEPPRDIRAWAFPEQSGIVRKSLDELRRELSGEAAPPPIEGVGELIGQNVTFRHRRARPTDRPGAGAHRFLPRGCQPIPSCSDGRAERHRCLGAAFKQPGASTHEKPHVAGFCRPPWSFATWPHDGAASARRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPA3</accession>
    <name>A0A518IPA3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Iodothyronine deiodinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_08730</name>
    </gene>
    <organism evidence="3 4">
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        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004800">
        <property type="term" value="F:thyroxine 5'-deiodinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000643">
        <property type="entry name" value="Iodothyronine_deiodinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11781">
        <property type="entry name" value="PTHR11781"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00837">
        <property type="entry name" value="T4_deiodinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="SSF47473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="1">
        <location>
            <begin position="146"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="2">
        <location>
            <begin position="223"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="398" mass="44135" checksum="ECC6238843763BE4" modified="2019-10-16" version="1">MFNKISFVTLGLLALPISVARCDEPSSDQATIGDQLTPEATAIESELRNTLLPDSEAIAMLDAIVNGSTLSGDDGWFPLAKADGRPEWNKVVKKYDTDADQEITLEEFKGTEADFSRLDRSGDKRLSQSDFDWTEHSLAPLPGQMMFFLADRDANGKVTRDEFAHLFDAFADGDTDYIALDDLRTQFLPPPPGARRQRADRPTPSTLIASLKKQEIGSLNAGPSVGDIAPDFTLKSLAGESVTLSKQIGEKPIVLIFGNFTCGPFRSQAGNIEKLYQRYNQRAKFFLVYVREAHPKDGWWMLSNQRAGIDIAQPNEIGSRRIIAQQCQSHLNLDMPFLVDEIDDTVGSSYSGMPNRLYLIDQQGAVAFKSGRGPFGFHPRQLEQALILLLNEEHHAVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPC0</accession>
    <name>A0A518IPC0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_08940</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="61" mass="6375" checksum="33F7E587C857D0AD" modified="2019-10-16" version="1">MLSINLSPGLLVSVFSKEVQKFGTVVTAFGLVVVIKPDTATSAIVTILATNSHVWTAGIQC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPM3</accession>
    <name>A0A518IPM3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Flagellar assembly protein H</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_10060</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018035">
        <property type="entry name" value="Flagellar_FliH/T3SS_HrpE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02108">
        <property type="entry name" value="FliH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0966">Cell projection</keyword>
    <keyword evidence="4" id="KW-0969">Cilium</keyword>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0282">Flagellum</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="FliH" evidence="3">
        <location>
            <begin position="93"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="28"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV55038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="230" mass="25347" checksum="FA019247A84C6506" modified="2019-10-16" version="1">MSTILKSKSGKQDPGFSGVAGFNLDDFANRASQEVAQAQQTAAAIIKQAHADAEAIQQQAREAGREEGLKEANEVIDQRVKVAVDSAVHSRLATLESAIDQLWETENDWLQQWQQNTLEIAFEVAQKLTRNAINQNDEILLGWANEALDAVRGARKITLAVHPETLSVLGQQLDRVVRRPGLPQETHIEPDEAVEPMGVVVRQEGGHIDLQLSTQLEKLAQHLGLQSEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPN3</accession>
    <name>A0A518IPN3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Tricarballylate dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_10230</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004792">
        <property type="entry name" value="BaiN-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023166">
        <property type="entry name" value="HI0933-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42887">
        <property type="entry name" value="PTHR42887"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00275">
        <property type="entry name" value="TIGR00275"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="425" mass="45250" checksum="5AAAB103244CAED6" modified="2019-10-16" version="1">MQNDFDIVVIGAGAAGMMAAAEAARRGRSVCVLEKANKAGVKILMSGGTRCNVTHDCDAAGIMEAFGKNGRFLRQALAELSPTDVVQMFRDLGVPTKVEPGGKIFPESDRALDVCQALQRRMTESGATLRLGSAVQNLSRTETGFQVDLDGQSLHCRSVIVTVGGMSYPGCGTVGDGYNWLQQLGHTILTPRPSLVPIVGGSAWTWELQGLTLPEAQVTVGKPGVAKKKGELAQRTGGLLFTHFGFSGPTAMDVSRAITAVEDLSTIELRINALPGWNDDRLSSWFDAKRASEPSRQLDKALCEILPRRLASALIEQAQIAGEKPLAELSGANRRLLVEGMLRNRMPIQGTRGFKKAEVTAGGVSLKEVDPRTMHSRIVDGLYIAGEILDLDGWIGGYNFQSAFSTGTVAGRSAAESLHDADAGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPZ6</accession>
    <name>A0A518IPZ6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Arylsulfatase</fullName>
            <ecNumber evidence="7">3.1.6.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">atsA_8</name>
        <name evidence="7" type="ORF">Mal33_11230</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="PTM">
        <text evidence="3">The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the sulfatase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.6.1" evidence="7"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004065">
        <property type="term" value="F:arylsulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024607">
        <property type="entry name" value="Sulfatase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00523">
        <property type="entry name" value="SULFATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021787024" evidence="5">
        <location>
            <begin position="19"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase" evidence="6">
        <location>
            <begin position="33"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="502"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="modified residue" description="3-oxoalanine (Cys)" evidence="3">
        <location>
            <position position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR600917-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV55154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="650" mass="71443" checksum="86D9BACEFCF0A1CC" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQ13</accession>
    <name>A0A518IQ13_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Glutamine-dependent NAD(+) synthetase</fullName>
            <ecNumber evidence="5 6">6.3.5.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5 6">NAD(+) synthase [glutamine-hydrolyzing]</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 9" type="primary">nadE</name>
        <name evidence="9" type="ORF">Mal33_11370</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>ATP + deamido-NAD(+) + H2O + L-glutamine = AMP + diphosphate + H(+) + L-glutamate + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:24384"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.5.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 5 6">Cofactor biosynthesis; NAD(+) biosynthesis; NAD(+) from deamido-NAD(+) (L-Gln route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5 6">In the C-terminal section; belongs to the NAD synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.1" evidence="5 6"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00334"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004359">
        <property type="term" value="F:glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003952">
        <property type="term" value="F:NAD+ synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008795">
        <property type="term" value="F:NAD+ synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00553">
        <property type="entry name" value="NAD_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02090">
        <property type="entry name" value="NadE_glutamine_dep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014445">
        <property type="entry name" value="Gln-dep_NAD_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041856">
        <property type="entry name" value="NAD+_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022310">
        <property type="entry name" value="NAD/GMP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003694">
        <property type="entry name" value="NAD_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23090">
        <property type="entry name" value="PTHR23090"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02540">
        <property type="entry name" value="NAD_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006630">
        <property type="entry name" value="NADS_GAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="SSF56317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 6 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 6" id="KW-0520">NAD</keyword>
    <keyword evidence="3 5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CN hydrolase" evidence="8">
        <location>
            <begin position="7"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="640"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for glutaminase activity" evidence="5">
        <location>
            <position position="45"/>
        </location>
    </feature>
    <feature type="active site" description="For glutaminase activity" evidence="5">
        <location>
            <position position="114"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile; for glutaminase activity" evidence="5">
        <location>
            <position position="167"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="200"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="360"/>
            <end position="367"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="468"/>
        </location>
        <ligand>
            <name>deamido-NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="487"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="492"/>
        </location>
        <ligand>
            <name>deamido-NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="497"/>
            <end position="500"/>
        </location>
        <ligand>
            <name>deamido-NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="626"/>
        </location>
        <ligand>
            <name>deamido-NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR006630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV55167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="660" mass="72551" checksum="66ABF559C3FDC500" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQ79</accession>
    <name>A0A518IQ79_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Formyltransferase/hydrolase complex Fhc subunit C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">fhcC</name>
        <name evidence="3" type="ORF">Mal33_12180</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FwdC/FmdC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018493">
        <property type="term" value="F:formylmethanofuran dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046914">
        <property type="term" value="F:transition metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015948">
        <property type="term" value="P:methanogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017550">
        <property type="entry name" value="Formylmethanofuran_DH_suC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002489">
        <property type="entry name" value="Glu_synth_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036485">
        <property type="entry name" value="Glu_synth_asu_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01493">
        <property type="entry name" value="GXGXG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69336">
        <property type="entry name" value="SSF69336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03122">
        <property type="entry name" value="one_C_dehyd_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GXGXG" evidence="2">
        <location>
            <begin position="78"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="273" mass="29124" checksum="ADA16644006007DA" modified="2019-10-16" version="1">MIRLKLKRQPKVPLQAERLSPDGLSGLSHDAICAIEILHGRRRCRVDEFFEVQGEGADELQIEGDLRKVQQIGSRMTHGTIAIRGDVGMHLGASMSGGKINVDGDAGDWAGAEMVGGEIHISRNAGDRIGGAYVGSLTGMKNGTILVDGTAGAEIGLRMRRGLIVVGGQAGELAGLQMKGGTIVLRGGAAARCGAWMRRGTIVSLQPVATLATHRYSTDYNPTFLNLYARHLQGFGIEIPYRSEEGGYARYCGDGSVRGKGEILVWQPRDASV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQI5</accession>
    <name>A0A518IQI5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_13230</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="72" mass="7848" checksum="1BE23D1841362133" modified="2019-10-16" version="1">MNQNELNRAVAAATGETVSAIKRLGFLIADPSVRIDDPSDPDLGGRVIDWDDFELLSEDLDEGRFDPEAAIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQJ6</accession>
    <name>A0A518IQJ6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Recombinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_13140</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000150">
        <property type="term" value="F:DNA strand exchange activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1750.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038109">
        <property type="entry name" value="DNA_bind_recomb_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011109">
        <property type="entry name" value="DNA_bind_recombinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006119">
        <property type="entry name" value="Resolv_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036162">
        <property type="entry name" value="Resolvase-like_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07508">
        <property type="entry name" value="Recombinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00239">
        <property type="entry name" value="Resolvase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00857">
        <property type="entry name" value="Resolvase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53041">
        <property type="entry name" value="SSF53041"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Resolvase/invertase-type recombinase catalytic" evidence="2">
        <location>
            <begin position="19"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="409"/>
            <end position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="650" mass="73735" checksum="EE9FD544DA6CD10D" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQM6</accession>
    <name>A0A518IQM6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Thioredoxin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">trxA_2</name>
        <name evidence="4" type="ORF">Mal33_13440</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021868086" evidence="2">
        <location>
            <begin position="28"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="3">
        <location>
            <begin position="20"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV55373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="161" mass="17852" checksum="DB222E3B73F934CA" modified="2019-10-16" version="1" precursor="true">MIWSAKLSIALLTVFAVLQMGCGSRVAENPLDDAQADGIKPVQLTDANFQTEVIESDLPVLVDMWAPWCGPCIEMKPTLRLVTEELTGQAKVAELNIDENPFIKEKYGIDRYPTLLIFRNGEEVDRLSGEKTEGELIEALSPFLSSSIEADDDTSPRDKHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQT0</accession>
    <name>A0A518IQT0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PEP-CTERM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_14250</name>
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    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
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            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027828">
        <property type="entry name" value="DUF4465"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013424">
        <property type="entry name" value="PEP_exosort_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14717">
        <property type="entry name" value="DUF4465"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07589">
        <property type="entry name" value="PEP-CTERM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02595">
        <property type="entry name" value="PEP_exosort"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021988701" description="PEP-CTERM domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="domain" description="PEP-CTERM" evidence="2">
        <location>
            <begin position="243"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="277" mass="29214" checksum="5FC6026C1AF6C519" modified="2019-10-16" version="1" precursor="true">MKIQLFALIISLAAATPSLADMVIDFDELSGYTDTTADGSYLNGYGYGAATGSWSSRGVTFGTNQWGPGWSYSNVNNTTTADYTNQFAAYPGTDVSGNGNYVIGTGFSPNAAYFNLSANLQAKSIAVANSTYAALSMLNGDGFAKPHGGDTGSDPDYFRVIFTGFEQADVGGASTGSVEFYLSDFRFSDDTLDYIVEDWQTVDLTGLGDARSIGITLDGNDVGEWGLNTPAYVAIDNLAVTAAVPEPGSMAMLSVALVAGGIARRRRSKRQQKNQTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQY9</accession>
    <name>A0A518IQY9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">6-carboxy-5,6,7,8-tetrahydropterin synthase</fullName>
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        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Queuosine biosynthesis protein QueD</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Mal33_14840</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>7,8-dihydroneopterin 3'-triphosphate + H2O = 6-carboxy-5,6,7,8-tetrahydropterin + acetaldehyde + 2 H(+) + triphosphate</text>
            <dbReference type="Rhea" id="RHEA:27966"/>
            <dbReference type="ChEBI" id="CHEBI:15343"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18036"/>
            <dbReference type="ChEBI" id="CHEBI:58462"/>
            <dbReference type="ChEBI" id="CHEBI:61032"/>
            <dbReference type="EC" id="4.1.2.50"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Purine metabolism; 7-cyano-7-deazaguanine biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the PTPS family. QueD subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.50" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00391"/>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070497">
        <property type="term" value="F:6-carboxy-5,6,7,8-tetrahydropterin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007115">
        <property type="entry name" value="6-PTP_synth/QueD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038418">
        <property type="entry name" value="6-PTP_synth/QueD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12589">
        <property type="entry name" value="PTHR12589"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01242">
        <property type="entry name" value="PTPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00018141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QDV55508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="164" mass="18595" checksum="0FBE26584193A9E4" modified="2019-10-16" version="1">MTASASYRVEVCKEAFVFSAAHFITFAGDICERLHGHNYGVKVAVEGPLDANRYVVDFIALRDAVLHETLQLDHHVLLPSEHAEIKVQEEDGEMVARFRERRWVFPKEDCIVLPVINTTAEELARVIAQRVREQTRAKFGDAIATIEVGVDENHGQWGVCRLPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IR73</accession>
    <name>A0A518IR73_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">(5-formylfuran-3-yl)methyl phosphate synthase</fullName>
            <ecNumber evidence="3">4.2.3.153</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">4-(hydroxymethyl)-2-furancarboxaldehyde-phosphate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Mal33_15660</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the formation of 4-(hydroxymethyl)-2-furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2 D-glyceraldehyde 3-phosphate = 4-(hydroxymethyl)-2-furancarboxaldehyde phosphate + 2 H2O + phosphate</text>
            <dbReference type="Rhea" id="RHEA:43536"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="ChEBI" id="CHEBI:83407"/>
            <dbReference type="EC" id="4.2.3.153"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="4.2.3.153" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007565">
        <property type="entry name" value="4HFCP_synth"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04476">
        <property type="entry name" value="4HFCP_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015957">
        <property type="entry name" value="UCP015957"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0704">Schiff base</keyword>
    <feature type="active site" description="Schiff-base intermediate with substrate" evidence="7">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00032523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR015957-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV55589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="259" mass="27082" checksum="AD0F51C6C9962989" modified="2019-10-16" version="1">MLQNTNKSAGLPIASPAVGGIARTDAVPLLISVRSIAEAKIACQFPLAIIDFKNPKAGALGRCSDAVLQRVASLKPTGLGFSAACGELRELQSHRLALPAGIRFAKAGPAGLCSASQIRDAMLRFRAALPDATTSVAVAYADHAEADCAPVETIAELAIQTEHRWVLIDTATKDGRRLLDWLTPQQLTDVISMGRQHGIGTVLAGSLALQDIDSLRSLGADLLGIRGAVCSGGRDSQIDPDKIAAWCQAMASAEAPIDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IR90</accession>
    <name>A0A518IR90_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Peptidyl-tRNA hydrolase</fullName>
            <shortName evidence="1">PTH</shortName>
            <ecNumber evidence="1">3.1.1.29</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1 2" type="primary">pth</name>
        <name evidence="2" type="ORF">Mal33_15850</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>an N-acyl-L-alpha-aminoacyl-tRNA + H2O = a tRNA + an N-acyl-L-amino acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:54448"/>
            <dbReference type="Rhea" id="RHEA-COMP:10123"/>
            <dbReference type="Rhea" id="RHEA-COMP:13883"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:59874"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:138191"/>
            <dbReference type="EC" id="3.1.1.29"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PTH family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.29" evidence="1"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004045">
        <property type="term" value="F:aminoacyl-tRNA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00462">
        <property type="entry name" value="PTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00083">
        <property type="entry name" value="Pept_tRNA_hydro_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001328">
        <property type="entry name" value="Pept_tRNA_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036416">
        <property type="entry name" value="Pept_tRNA_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17224">
        <property type="entry name" value="PTHR17224"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01195">
        <property type="entry name" value="Pept_tRNA_hydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53178">
        <property type="entry name" value="SSF53178"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00447">
        <property type="entry name" value="pth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="191" mass="20677" checksum="8A0F255135CF522B" modified="2019-10-16" version="1">MKLIVGLGNPGIRYAHTRHNIGFMAAAKFAQQIGASETRNRFDGEVAEGQVAGTKAIVLCPSTYMNASGGSVRKAVGFYKIDPADVLVICDDFNLALGRLRVRAKGSSGGQKGLADIIRLLGTEEVPRLRIGISPPPAGWNIPDYVLSKFRSDEEVDVERVTDRAAQAAHDFVRHDVAFCMNAYNGTELDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRA0</accession>
    <name>A0A518IRA0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycogen synthase</fullName>
            <ecNumber evidence="3">2.4.1.11</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_15970</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.4.1.11" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004373">
        <property type="term" value="F:glycogen (starch) synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="18"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="358"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="364"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="387" mass="43006" checksum="2CE59BC037E924E9" modified="2019-10-16" version="1">MRIAWISYGFEELCVQNVNALAEEHEVLLVMPHPQPGETQYAISDRVKHFGFDEPRLRQPLRQLSCVAAIRRQIDAFKPDVVHFQQGHMWFNTALRSLKRYPLVATIHDPRHHAGDMSSRKTPQWVMDYGFRKADHVIVHGEALAAQVQQLFGFASDRVHVVAHVAMGQVEGASAVPEEPHNVLFFGRIWDYKGLEYLIAAEPLIAAEVPDAKIVIAGRGDDFSRYQKLIGDSPRFEIHNRWISDQQRAEFFQRAAIVVLPYTEATQSGVVPVAQMYAKPVVATRVGALAECVLDRQTGLLVPPRDPQALATAIIQLLKDPAQRRALGDAGFDRLQAEASPAVVARQTVAVYEQAIADRQRGSKPSPAQASAVQSTQTIGSPSHVNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRC0</accession>
    <name>A0A518IRC0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Inositol 2-dehydrogenase</fullName>
            <ecNumber evidence="3">1.1.1.18</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">iolG_5</name>
        <name evidence="3" type="ORF">Mal33_15910</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.1.18" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050112">
        <property type="term" value="F:inositol 2-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004104">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02894">
        <property type="entry name" value="GFO_IDH_MocA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GFO_IDH_MocA" evidence="1">
        <location>
            <begin position="2"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="GFO_IDH_MocA_C" evidence="2">
        <location>
            <begin position="133"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="344" mass="38203" checksum="01BD31D6F38F2DFA" modified="2019-10-16" version="1">MIRVGIVGLGYWGPNLVRCFSDIEGAKVTAVCDQSRDNLCRITDHFRGVTPFESFQEMLDRDVIDAVVIATPTATHFQLASDALKHGLHVFVEKPLAKTSEECRKLIDLAEQHHRTLFVGHVFLHSAPVMKLREIIASGELGNINYISSRRLNLGPVRTDVSALYDLAPHDISMMLYLLDQQPETVTCSGFDRLNPGIHDVCNVSMKFAGNRMGMIHVSWLDPRKERVLTVVGDKKMAIYDDLEQEKIKIFDKGIDAPPPASGDFADFQMSYRYGGSYSPFVQEREPLKAECADFIRCIVDDDVPLTDGVNGLQVVEVLEAAHHSLHQGGQPVDLVAARSIATS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRE6</accession>
    <name>A0A518IRE6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative sugar transferase EpsL</fullName>
            <ecNumber evidence="4">2.-.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">epsL_1</name>
        <name evidence="4" type="ORF">Mal33_15900</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial sugar transferase family.</text>
    </comment>
    <dbReference type="EC" id="2.-.-.-" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003362">
        <property type="entry name" value="Bact_transf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02397">
        <property type="entry name" value="Bac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="56"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="Bac_transf" evidence="3">
        <location>
            <begin position="51"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV55613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="245" mass="27866" checksum="FC99B4CA62B4B687" modified="2019-10-16" version="1">MRSEESCLLEQPLQTAEGTLTRRDRRGGSFVGSRVAEATPLPECLGTPWWKRGCDIVGASLLLCLLLPFLLAVACYIRIVSKGPALFFQRRVGEGGKHFNIIKFRTMDVRPEATAEHRVYVERLTTQDAPIEKPDHTNRIIPGGNFLRRNSIDEFPQLLNVLIGTMSLVGPRPDLLEIEDYEPWQLRRFAVLPGMTGLWQVSGKNRLTFREMIQLDIQYVEARSFALDLRILLKTFSVVVQQDND</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRE9</accession>
    <name>A0A518IRE9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Outer membrane biogenesis protein BamB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_16410</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025666">
        <property type="entry name" value="PQQ-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018391">
        <property type="entry name" value="PQQ_beta_propeller_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002372">
        <property type="entry name" value="PQQ_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13360">
        <property type="entry name" value="PQQ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13570">
        <property type="entry name" value="PQQ_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00564">
        <property type="entry name" value="PQQ"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021761381" evidence="1">
        <location>
            <begin position="25"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="domain" description="PQQ_3" evidence="2">
        <location>
            <begin position="55"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13570"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="445" mass="48490" checksum="F463B385A6B80200" modified="2019-10-16" version="1" precursor="true">MNTLPFCRSLGVVATLLLTTQIVAAVEWSQFRGTAGDGIADVTHAPTQWSETENVVWKTPIAGKGWSSPVVADGKVWMTTAIEEQATEEERIATLERLVENPRRFGEFRLAKSITLRLVAVDLATGAQEMEIDLVRLDHPDPIHTINSYASPTPVIDGDNIYCHFGTFGTICVDRKKGVEVWRKRLPLEHGVGPGSSPFVYKNALVLICDGMDQQYVTALDKSTGETLWRTDRPPLDAASGEQKKSYDTPIAIIDAAGREQLICMGSQWLVAYDPTDGSEIWKVRHGKGFSVVPRPVYGDGTVYISTGFGKPQLWAIRVDGSGDVTDTHVAWVEKKGIPAKPSPLLIDGELYVISDDGIASCFDAASGELVWKQRVGGKYSASPLMAAGKIYLCSHEGKVSVLKPGREYQLLAENQLDGQLMASPAALGDSLLIRSDTALYRIAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRN4</accession>
    <name>A0A518IRN4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fumarylacetoacetate (FAA) hydrolase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_17290</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.850.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011234">
        <property type="entry name" value="Fumarylacetoacetase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036663">
        <property type="entry name" value="Fumarylacetoacetase_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01557">
        <property type="entry name" value="FAA_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56529">
        <property type="entry name" value="SSF56529"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAA_hydrolase" evidence="1">
        <location>
            <begin position="149"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="284" mass="30827" checksum="235DCF7276D5D581" modified="2019-10-16" version="1">MKLAKFKQPNGLVAAGIVEGDSIQALDLSAGKFEALSDLLDAKDIPAAVDYLPKRDPHALDSVQLLPPIDRQEVWAAGVTYKRSQTARMEESEAAASCYDRVYVADRPELFLKATPHRVRGDGQELRIRTDATWNVPEPEVTLVLNSRMQIVGYTIGNDMSSRDIEGENPLYLPQAKVYDQCAGLGPWITLSSDMPPREQMTIDLKIERGGDVVFEQSTDAAQMARGFEDLAGWLGRDNSFPNGAFLMTGTGIVPGSDFTLAAGDVVRISIAGIGTLTNSIVQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRQ7</accession>
    <name>A0A518IRQ7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Twitching mobility protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">pilT_1</name>
        <name evidence="4" type="ORF">Mal33_17660</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GSP E family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006321">
        <property type="entry name" value="PilT/PilU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001482">
        <property type="entry name" value="T2SS/T4SS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00437">
        <property type="entry name" value="T2SSE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01420">
        <property type="entry name" value="pilT_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00662">
        <property type="entry name" value="T2SP_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T2SP_E" evidence="3">
        <location>
            <begin position="237"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV55787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="405" mass="44847" checksum="52BFA33328B7D7F6" modified="2019-10-16" version="1">MKPKTAEKPAIPAPDPSISPEAQRTAMMARLKSSLLQEKKELPVDKIFRALVKLEGSDLHLKVGQPPMVRVGGELKPLNRGPIDTEEMVDLLLPMMDQRNLMIFEEEGGADFSYQCEVDGVRWRFRINMLKSLGNMGLVARRISNFIPDFRGLFLPESIEKLCHYEQGMVLLAGVTGSGKSTTIGSMLNYINSIYRKHILTLEDPIEFIFTEDKSLINQREIGQDVLDFSIGMKHAVREDPDIILVGELRDEETFMTAIHAAETGHLVFGTIHAASASTCIGRILDLFPESLHGAIRSAIAFNMKGIVAQKLLRSIKPGVSRVPTCEVMTFTPMITKLILEGHDSKLPDAIRIGAEDGMQDFTMSLKQLIDDELIDRPTAFAVAPNKDALKMALKGIDVKAPGII</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IS01</accession>
    <name>A0A518IS01_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uracil DNA glycosylase superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_18550</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017065">
        <property type="term" value="F:single-strand selective uracil DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19374">
        <property type="entry name" value="UDG-F3_SMUG1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039134">
        <property type="entry name" value="SMUG1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036895">
        <property type="entry name" value="Uracil-DNA_glycosylase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13235">
        <property type="entry name" value="PTHR13235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52141">
        <property type="entry name" value="SSF52141"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV55876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="249" mass="27784" checksum="9641F6448B5EE6EC" modified="2019-10-16" version="1">MARRWADINMPNKTATRLIEAAANLADEVDRLSFAEPVTHVYNPLRYAAAAHRMYLSRYAKPTCKVLLLGMNPGPWGMSQTGVPFGEIDAVRNWMKIETEVEKPDPEHPKRPIEGFACQRSEVSGRRLWGLFAERFPDPKDFFKTHFVANYCPLVFMEASARNVTPDKLSKAERGALEQVCDAHLAEVIEALDPTWVVGVGAFAEKCAGRVLTGDRKLAKILHPSPASPAANRGWAEAATKQLEDLQIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IS78</accession>
    <name>A0A518IS78_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_19090</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021986391" evidence="2">
        <location>
            <begin position="26"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="254"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="257"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="346" mass="38238" checksum="3CC00CD4129CA0FA" modified="2019-10-16" version="1" precursor="true">MKRIATHVAALLVAWTSSSVSLAFAADDSLQQEAEWAMADDARVTEAMQLGLTEQGLDATKIEAAMGSLGQLMQAGQADPLDAFIRASVVALPKLAEKLQQIEQSPSSIGDDPFLAFVPTVRDQARLWAGRALVRVRLFDEAIPLLQSLEPIDVVAPAELLFYRGACYHALLKKDEAIDDLSALLQRKAEIPQRFARTAELMLADIQPLKEDSLDEIARLMNDVSRRLDLGRAGDPVVEREQQIIDKLDQMIEKMEEQQKQQQQQMQQAQSGGQGGSQSKPMEDSQIAGGSGPGDVDRKKLGDRDGWGNLPPAQRQEALQKISQDLPTHYREAIEAYFRKLATEKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IS94</accession>
    <name>A0A518IS94_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_19290</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026350">
        <property type="entry name" value="GxxExxY"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13366">
        <property type="entry name" value="PDDEXK_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04256">
        <property type="entry name" value="GxxExxY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="129" mass="15035" checksum="62E68FCDE8A77D98" modified="2019-10-16" version="1">MPEDLIFREECYKIIGACFEVYNDKGCGFLEPVYQECLEIEHEYQQIPFVPRQAIGLSYRGIELKQKLIPDFICYGKIILEIKAVSQLIDEHRAQVINYLNASGFQLGLLVNFASYPKIQWERFVHTAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IS96</accession>
    <name>A0A518IS96_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 7">Aldose 1-epimerase</fullName>
            <ecNumber evidence="4 7">5.1.3.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">mro_2</name>
        <name evidence="11" type="ORF">Mal33_19460</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>alpha-D-glucose = beta-D-glucose</text>
            <dbReference type="Rhea" id="RHEA:10264"/>
            <dbReference type="ChEBI" id="CHEBI:15903"/>
            <dbReference type="ChEBI" id="CHEBI:17925"/>
            <dbReference type="EC" id="5.1.3.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Carbohydrate metabolism; hexose metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the aldose epimerase family.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.3" evidence="4 7"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00242"/>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004034">
        <property type="term" value="F:aldose 1-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019318">
        <property type="term" value="P:hexose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018052">
        <property type="entry name" value="Ald1_epimerase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015443">
        <property type="entry name" value="Aldose_1-epimerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008183">
        <property type="entry name" value="Aldose_1/G6P_1-epimerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01263">
        <property type="entry name" value="Aldose_epim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005096">
        <property type="entry name" value="GALM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="SSF74650"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00545">
        <property type="entry name" value="ALDOSE_1_EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6 7 11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="80"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="180"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8">
        <location>
            <position position="180"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="310"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="248"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00014165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR005096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR005096-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR005096-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR005096-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QDV55967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="345" mass="37842" checksum="AB95C6F8C99D6072" modified="2019-10-16" version="1">MKIEQRPFGTTSDGHAVTLFTLTNNHGNSVELIDRGATIVSVNVPDRDGKRGNVNLGFSALDGYLQRHPYFGSTVGRVCNRIANGRFAIDGREYQVAQNLGAHHLHGGLVAFDALMWTAEPVQTSWQVGVRMRLVSPDGDEGYPGTLDTTVEFTWNDDNELTYTFTAETDAPTHLNLTNHAYWNLAGAGSGTARDHVVTIQADQSLEVDDDLIPTGRQIDVAESVLDFRQPRVIGDRIDELPETKGYDHCYVLRGTPGELRPAALAVDPASGRTMEVMTTQPCMQLYTGNHLSGQADAGGFRQHEAFCFETQHPPNAANQSAFATTRLNPGETFKQTTLHRFGIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISK7</accession>
    <name>A0A518ISK7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_20530</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="262" mass="29348" checksum="800BF038E07FD452" modified="2019-10-16" version="1">MKSLLRSITTTAGILITACCLLGADPAEPSPSVTEESWGEIVWKPSSLELHVQSLPEDRKISFPRLNNRMKSLYMQGEDPEQTKLKFRPEPKTWDITFPKDVDPQGKVVVFETMEPVLLARQPHRISQSKDGSFTLAAHHAVTHGKLLRYEPQPRKNTVGYWADANDWAQWQLHVSQPMEFQVEVLQGCGKGHGGSTVAIELAGKTVRFVVEDTGHFQNFKPRQIGTIRVDAAGDYSLDLRAIEKVKGAVCDIRQIRLIPTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISL0</accession>
    <name>A0A518ISL0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10 14">Catalase</fullName>
            <ecNumber evidence="3 10 14">1.11.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">katE</name>
        <name evidence="17" type="ORF">Mal33_20600</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Serves to protect cells from the toxic effects of hydrogen peroxide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 14">
            <text>2 H2O2 = 2 H2O + O2</text>
            <dbReference type="Rhea" id="RHEA:20309"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="EC" id="1.11.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10 12">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the catalase family. HPII subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.6" evidence="3 10 14"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004096">
        <property type="term" value="F:catalase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03132">
        <property type="entry name" value="GATase1_catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1370.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018028">
        <property type="entry name" value="Catalase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024708">
        <property type="entry name" value="Catalase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024712">
        <property type="entry name" value="Catalase_clade2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043156">
        <property type="entry name" value="Catalase_clade2_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011614">
        <property type="entry name" value="Catalase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002226">
        <property type="entry name" value="Catalase_haem_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010582">
        <property type="entry name" value="Catalase_immune_responsive"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041399">
        <property type="entry name" value="Catalase_large_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020835">
        <property type="entry name" value="Catalase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42821">
        <property type="entry name" value="PTHR42821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00199">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06628">
        <property type="entry name" value="Catalase-rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18011">
        <property type="entry name" value="Catalase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038927">
        <property type="entry name" value="Catalase_clade2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00067">
        <property type="entry name" value="CATALASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01060">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56634">
        <property type="entry name" value="SSF56634"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00437">
        <property type="entry name" value="CATALASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00438">
        <property type="entry name" value="CATALASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51402">
        <property type="entry name" value="CATALASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10 13" id="KW-0349">Heme</keyword>
    <keyword evidence="9 10 14" id="KW-0376">Hydrogen peroxide</keyword>
    <keyword evidence="8 10 12" id="KW-0408">Iron</keyword>
    <keyword evidence="6 10 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 10 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 10 14" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Catalase" evidence="16">
        <location>
            <begin position="34"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="81"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="154"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="78"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="364"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="12">
        <location>
            <position position="368"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="375"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR038927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR038927-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR038927-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR038927-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM01060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="QDV56081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="697" mass="77524" checksum="E41C7A4279081B4B" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISM2</accession>
    <name>A0A518ISM2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative periplasmic serine endoprotease DegP-like</fullName>
            <ecNumber evidence="3">3.4.21.107</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">mucD_3</name>
        <name evidence="3" type="ORF">Mal33_20710</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.4.21.107" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001940">
        <property type="entry name" value="Peptidase_S1C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13180">
        <property type="entry name" value="PDZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00834">
        <property type="entry name" value="PROTEASES2C"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021719691" evidence="1">
        <location>
            <begin position="35"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="2">
        <location>
            <begin position="277"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="381" mass="40717" checksum="E57E497312833AD5" modified="2019-10-16" version="1" precursor="true">MITPMNPPRIGKPRWLRLILIVAILCAPWAKANAQDDTGPRALSRAFQNAAKLATASVVTVIAYGQNLDDQGMPVGADEADDFDIESPDDGDELSDLDDIPHTKEMLPATGLGSGVILTAEGLIISNNHVIRDARRVIVRLHDGLEITATKVLGDPASDIAIIQIETEEKLVAARLGNSKDLQIGEWVLAIGSPFRLDATVSAGIISAIGRRLDAIRRGRLLQTDAAINPGNSGGPLINLDGEVVGISTAIATRSGGYQGIGFAVPINQANWIARELAEFGEVRRASIGLSLAMLNARIARQLELPMKTGILVVAVTKNHAAAKAGVEPYDVILEFNGQPIVKPRDLQEAIEREPIGSTQQLTLFRKGERLELTVTLEAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISV9</accession>
    <name>A0A518ISV9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Probable dual-specificity RNA methyltransferase RlmN</fullName>
            <ecNumber evidence="11">2.1.1.192</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">23S rRNA (adenine(2503)-C(2))-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">23S rRNA m2A2503 methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Ribosomal RNA large subunit methyltransferase N</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">tRNA (adenine(37)-C(2))-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">tRNA m2A37 methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11 13" type="primary">rlmN</name>
        <name evidence="13" type="ORF">Mal33_21380</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>adenosine(2503) in 23S rRNA + 2 reduced [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine = 2-methyladenosine(2503) in 23S rRNA + 5'-deoxyadenosine + L-methionine + 2 oxidized [2Fe-2S]-[ferredoxin] + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42916"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="Rhea" id="RHEA-COMP:10152"/>
            <dbReference type="Rhea" id="RHEA-COMP:10282"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74497"/>
            <dbReference type="EC" id="2.1.1.192"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>adenosine(37) in tRNA + 2 reduced [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine = 2-methyladenosine(37) in tRNA + 5'-deoxyadenosine + L-methionine + 2 oxidized [2Fe-2S]-[ferredoxin] + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:43332"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="Rhea" id="RHEA-COMP:10162"/>
            <dbReference type="Rhea" id="RHEA-COMP:10485"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74497"/>
            <dbReference type="EC" id="2.1.1.192"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="11">Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="11">Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.</text>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the radical SAM superfamily. RlmN family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.192" evidence="11"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="term" value="F:rRNA (adenine-C2-)-methyltransferase activity"/>
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        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="term" value="F:tRNA (adenine-C2-)-methyltransferase activity"/>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="Aldolase_TIM"/>
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    </dbReference>
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        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30544">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="CHP00048"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00275">
        <property type="entry name" value="adenosine_C2_methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="rRNA_mod_RlmN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 11" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="3 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9 11" id="KW-0408">Iron</keyword>
    <keyword evidence="10 11" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 11 13" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="7 11" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6 11 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="11" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Radical SAM core" evidence="12">
        <location>
            <begin position="110"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="11">
        <location>
            <begin position="173"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="11">
        <location>
            <begin position="228"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="11">
        <location>
            <position position="104"/>
        </location>
    </feature>
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        <location>
            <position position="347"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
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        </ligand>
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        <location>
            <position position="131"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
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        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="205"/>
        </location>
        <ligand>
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        </ligand>
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        <location>
            <position position="304"/>
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        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
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            <dbReference type="ARBA" id="ARBA00004496"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="HAMAP-Rule" id="MF_01849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="QDV56159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="365" mass="40433" checksum="8B009769362092B8" modified="2019-10-16" version="1">MTDTPGDLETSPPQRRSLLDLHRDELVGWLAEQKQPKFRAAQILRWVYQQRAMSFEEMTDLPAKLRQRLAEDFDLFTASVEVEQVSHDGTEKLLIRLRDGGEVECVLLRDGPRRSICVSSQVGCAMGCVFCASGLDGVKRNLTHGEIMEQMLRLQRRLPADERLSHIVMMGMGEPLANLDNVLATLDIARDADGLGISPRRITISTVGLPPAIDRLARHGVPYNLAVSLHAPNDELRNRLVPVNVKVGIDKILASADRYFATSGRRLTYEYVLLGGVNDSIQQAHELVGLLRGRSALLNVIPYNPVAGLPYKTPSAGAVTQFREALEQGGVNVQFRTRKGSDIDAACGQLRRNREQLTESQLPLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IT07</accession>
    <name>A0A518IT07_9BACT</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_22160</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
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            <taxon>Pirellulales</taxon>
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            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="90" mass="9999" checksum="2BE9D851ABFFD830" modified="2019-10-16" version="1">MKRLFNLGAVVGTPASLAFLEKHNITPIQLLQRHVTGDFGDLCEEDCQLNHEAIKNGERILSAFEIGGDKLYLITEADRSSTCCLMANEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IT71</accession>
    <name>A0A518IT71_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Site-specific DNA-methyltransferase (cytosine-N(4)-specific)</fullName>
            <ecNumber evidence="3">2.1.1.113</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">pvuIIM</name>
        <name evidence="9" type="ORF">Mal33_22630</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2'-deoxycytidine in DNA + S-adenosyl-L-methionine = an N(4)-methyl-2'-deoxycytidine in DNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:16857"/>
            <dbReference type="Rhea" id="RHEA-COMP:11369"/>
            <dbReference type="Rhea" id="RHEA-COMP:13674"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:85452"/>
            <dbReference type="ChEBI" id="CHEBI:137933"/>
            <dbReference type="EC" id="2.1.1.113"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.113" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="REBASE" id="356951">
        <property type="entry name" value="M.PbaMal33ORF22630P"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008170">
        <property type="term" value="F:N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015667">
        <property type="term" value="F:site-specific DNA-methyltransferase (cytosine-N4-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002941">
        <property type="entry name" value="DNA_methylase_N4/N6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017985">
        <property type="entry name" value="MeTrfase_CN4_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001091">
        <property type="entry name" value="RM_Methyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01555">
        <property type="entry name" value="N6_N4_Mtase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00508">
        <property type="entry name" value="S21N4MTFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00093">
        <property type="entry name" value="N4_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N6_N4_Mtase" evidence="8">
        <location>
            <begin position="44"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="domain" description="N6_N4_Mtase" evidence="8">
        <location>
            <begin position="421"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="241"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV56281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="669" mass="74896" checksum="D4F30AE0B3810596" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IT93</accession>
    <name>A0A518IT93_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pseudouridine synthase</fullName>
            <ecNumber evidence="3">5.4.99.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rluD_2</name>
        <name evidence="5" type="ORF">Mal33_22830</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Responsible for synthesis of pseudouridine from uracil.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a uridine in RNA = a pseudouridine in RNA</text>
            <dbReference type="Rhea" id="RHEA:48348"/>
            <dbReference type="Rhea" id="RHEA-COMP:12068"/>
            <dbReference type="Rhea" id="RHEA-COMP:12069"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the pseudouridine synthase RluA family.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.-" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120159">
        <property type="term" value="F:rRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000455">
        <property type="term" value="P:enzyme-directed rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd02869">
        <property type="entry name" value="PseudoU_synth_RluA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006225">
        <property type="entry name" value="PsdUridine_synth_RluC/D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006224">
        <property type="entry name" value="PsdUridine_synth_RluC/D_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00005">
        <property type="entry name" value="rluA_subfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01129">
        <property type="entry name" value="PSI_RLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S4" evidence="4">
        <location>
            <begin position="16"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR606225-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV56301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="309" mass="34670" checksum="57FBA88CCFD9D174" modified="2019-10-16" version="1">MAMTTVSTTITAEDAGRVDLVVRELSKASRSQVRGMVDHGCVSINGKPCTAIAATVSVGDEVAVRYDPHQRYHEKKKIWEDRTFTVAYEDDYLIVVDKSAGSLTVPTDNNNDRNTLVERVSIYLSHSRKKREACVVHRLDREVSGLLVFGKQPDVAEALIQQFKQRKPQRLYAAIVAGSLAQDEGTFRSHLATGKNLDRYVAPPSEKSELAITHYRVLRRMADTTLVEVQLETGKRNQIRVHFADAGHPVLGDPRYKKEAAKHPRWIRKRIALHAKSLGFVHPANGEEMTIDSPLPAAMEKFIASQRHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITB9</accession>
    <name>A0A518ITB9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HGSNAT_cat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_23130</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012429">
        <property type="entry name" value="HGSNAT_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07786">
        <property type="entry name" value="HGSNAT_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="140"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="166"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="203"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="231"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="320"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="353"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="382"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="domain" description="HGSNAT_cat" evidence="2">
        <location>
            <begin position="20"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="412" mass="45904" checksum="05D59DF3B27E94D8" modified="2019-10-16" version="1">MTAAIKTTPAAAEGSEARKRIVSLDQFRGYTVAGMLLVNFLASFSVSPAVLKHHHDYCSYADTIMPQFLFAVGFAFRLTFGRRVQRDGAAAANWRMVRRLLGLMLVSIVIYNVSPPASTWEELVALGPAGILPELLKRNWFQTLMHIAVTSLWILPVIAATARVRCLWMVGSAIAHVLLSYWFNYAWVNTSPNGIDGGPLGFLTWSVPTVMGTLVCDAVMAAAGRAPLLRLASWGCGLILLGYAMSCGTRMYDVTPTLPISASDSKLADDPVLPTAAQFHRWWDAKAWSDRLAEPPFVAPPDQSHRKWNYWMMSQRGGTLSYVTFCAGVSVLVYLLFYIACDRFTLRWSFFQTFGTNALAAYVLHEMVGMAVKPFIPRDSPGWYVASGLLLFFLITWTFVRSLEKQKIFLRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITR7</accession>
    <name>A0A518ITR7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_24500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="121" mass="13730" checksum="F77C0BBDB9AE7E10" modified="2019-10-16" version="1">MQLSYGTEPTIFQVKQMSKRERFLIGNPGSYDPLGDRNKASDEVERWVVDKYGPIETEHVGMPQFVDCIIVAAAVPLLRGVLIGMGPSRQLAIHDLYLRLTTNPELETSLPPWWQKRFEGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITV3</accession>
    <name>A0A518ITV3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Phage-related minor tail protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_25100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010090">
        <property type="entry name" value="Phage_tape_meas"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10145">
        <property type="entry name" value="PhageMin_Tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01760">
        <property type="entry name" value="tape_meas_TP901"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PhageMin_Tail" evidence="3">
        <location>
            <begin position="469"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="381"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="935"/>
            <end position="984"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="153"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="279"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="869"/>
            <end position="915"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="381"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="946"/>
            <end position="968"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF10145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV56519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1033" mass="113673" checksum="CD5AB2603E6ECAB7" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITY1</accession>
    <name>A0A518ITY1_9BACT</name>
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        <submittedName>
            <fullName evidence="8">Neutral/alkaline non-lysosomal ceramidase</fullName>
        </submittedName>
    </protein>
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        <name evidence="8" type="ORF">Mal33_25390</name>
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    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
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            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="QDV56547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
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        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
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        <property type="entry name" value="ARM-like"/>
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        <property type="entry name" value="ARM-type_fold"/>
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        <property type="entry name" value="Cyt_c-like_dom"/>
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        <property type="entry name" value="Cyt_c-like_dom_sf"/>
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    <dbReference type="InterPro" id="IPR002327">
        <property type="entry name" value="Cyt_c_1A/1B"/>
    </dbReference>
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        <property type="entry name" value="Haem-bd_dom_put"/>
    </dbReference>
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        <property type="entry name" value="Membrane-bound_put_N"/>
    </dbReference>
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        <property type="entry name" value="NEUT/ALK_ceramidase_N"/>
    </dbReference>
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        <property type="entry name" value="PBS_lyase_HEAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011041">
        <property type="entry name" value="Quinoprot_gluc/sorb_DH"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04734">
        <property type="entry name" value="Ceramidase_alk"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="2"/>
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        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="CxxCH_TIGR02603"/>
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    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
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        <location>
            <begin position="1285"/>
            <end position="1418"/>
        </location>
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    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="171"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
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    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV56547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1683" mass="183298" checksum="CA05D7418184C44E" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IU19</accession>
    <name>A0A518IU19_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="1" type="ORF">Mal33_25640</name>
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    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetes</taxon>
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    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="entry name" value="DUF4416"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14385">
        <property type="entry name" value="DUF4416"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="187" mass="21791" checksum="B2C78BE443DB7A63" modified="2019-10-16" version="1">MGVVRMPESVMPLCAITTRYDDALDWSVETFAAAGFQVRLKSELFAFDMTNYYQAEMGNDLKKQIFAFEPLRDPQQLADWKLLTNQWELDFKAQNSYPEDRPLNLDSGYLTLAKFVLATTKDRDHRLYLRDGIFAEVTMSFTGGSWKMHPWTYPDYQTEPAMNFLNAAREELKALFKEARRADSEKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUC1</accession>
    <name>A0A518IUC1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">Mal33_26800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
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        <location>
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            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022024095" evidence="1">
        <location>
            <begin position="34"/>
            <end position="498"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="498" mass="53145" checksum="51C79191758ECE02" modified="2019-10-16" version="1" precursor="true">MFPIPMEPVMSFPNRLSLAALLFASVLARPADAQTFDLIVPGSGLRSTAQLTADRLVIVDANGQASIYDRDPQLDANGYAAYSSQAMGQSIRWPLRGAGNMQVASLAGPLGSIAFRSTQMIVSPRGNGGLNPGVPGVLPGNQVGPQVAGNPSNDPKSVYVIESALGPGLLLSVAPLAGANVRIETQATGGQNVFFRLLPTDSGYVSIVPMKDRGLAIGMATGLAGNQGNAQLFDRRMGGGDAMQFRIVPDNAGFVTLELRANRDFVIDVVKPRGGRPASVGIFTRHGLQNQLFRLQRVGAMGNLPPGGFPPPIGNPVGPVLISKTVEPNPPLAPVQVQLSNSHANALWVLVTDLRDPDNSQRLKIPAGESRPATFERDPGSRVVSLLEVLQPNGVRVREESVVDVPPQPLYDISVYEMIPQSVYIDRTQPGSAPEVQHAPRSVGFFQVTATFEGGRSDVYRAAKRQNNSGGVRRLELKDWDWDEGDPEDAFSGRNSSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUF6</accession>
    <name>A0A518IUF6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Arylsulfatase</fullName>
            <ecNumber evidence="4">3.1.6.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">atsA_22</name>
        <name evidence="4" type="ORF">Mal33_27230</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="PTM">
        <text evidence="1">The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.</text>
    </comment>
    <dbReference type="EC" id="3.1.6.1" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="F:arylsulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sulfatase" evidence="3">
        <location>
            <begin position="54"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="486"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="modified residue" description="3-oxoalanine (Cys)" evidence="1">
        <location>
            <position position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR600917-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV56725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="509" mass="56340" checksum="9EF42BDE182D2645" modified="2019-10-16" version="1">MLSSHPPIQSSGIHRRPWAIRTWTPAIATPLSLLICLLVGGSASQRAAAAERLPNVVVIFIDDMGYEDIGPFGAEGIETPNLDAMAQQGRRFTDFVVSSAVCSASRAALMTGCYNRRLGISGAFGPGSKAGLNPDEMTIAELCKQKDYATAIYGKWHLGHLKPFLPLQHGFDEYFGLPYSNDMWPYHPNVLHLPMEQRVKRWPHLPLIEGNETINPQVSGEDQEQLTTQYTERAVSFIERNKDKPFFLYVPHSMVHVPLYVSEKFKGKSKRGLFGDVVMEVDWSVGQINAALKKNGIEDDTLVIFTSDNGPWLSYGDHAGVTSLREGKGTMFEGGYRVPTVMKWPGKIPAGTTCDQLASTIDILPTVANLIGAELPKHKIDGKDIGPLMFDKEGEAKSPHEAFYCYYSGGELHAVRNDRWKLHFPHRYRTLAGKPGGTDGLPTNYQHTTIGLELFDLDNDVNETTNVIDQHPEVVAMLKQHAEAARNDLGDKLTKRPPTGARPPGRVDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUJ0</accession>
    <name>A0A518IUJ0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF5658 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_27540</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043717">
        <property type="entry name" value="DUF5658"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18902">
        <property type="entry name" value="DUF5658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="SSF46565"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="170"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="198"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="DUF5658" evidence="3">
        <location>
            <begin position="133"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF18902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV56755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="222" mass="24457" checksum="AD86BD23FAD0941E" modified="2019-10-16" version="1">MDAIKQACRVLGVDEAASAAQIEAVYREKESRYQADPGSDPWDFQQVQQAYQILRRRAAAATVPAPSAAAKSQPQAFRDSPAKDARRSPGSAAPRSIQELPPAAASPEMPKHLLWQTFFRELPLQSETSYFLLANLLDVFMTYGLLKFGGIETNPIANYFLQRWGFDGMIALKMGSVAFVVILVQQIAVRDLTKARRLLIAGTAIVFAVVVYSGVLLSRVIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUL0</accession>
    <name>A0A518IUL0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">pknB_12</name>
        <name evidence="10" type="ORF">Mal33_27750</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="24"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="403"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="703"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="432"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV56776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="731" mass="79788" checksum="54A99E7A14E7DD72" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUP5</accession>
    <name>A0A518IUP5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_27790</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="283" mass="30104" checksum="B4D1127ECCE1E42E" modified="2019-10-16" version="1">MNDSTSKSSSSRKSPTKLTAGGGAIGILIVLYALLQPILSKQLGIDLPKFPVKVGADAPMVAGPDKPTEPSTEESKSAAPKIVVQSPSGDRPVDKDSAATNTASKRDRQDSAAPKTGSGPLSQFNRSSKSDDAKLSPTKSAADKTSSAKSDPSLKYGILKSIGRDTYMSPAGLRYTPGSQEGHRLKHLERHTADQPSRPGKHGVFDGGMEKTLLVLDQAYEKGTKGGHGTTKTQDDGRTIYTVDMGKRVGYIGGRDGNRMRKPMARRVRIVLDGDRVITAYPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUS1</accession>
    <name>A0A518IUS1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_28100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011453">
        <property type="entry name" value="DUF1559"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027558">
        <property type="entry name" value="Pre_pil_HX9DG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07596">
        <property type="entry name" value="SBP_bac_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04294">
        <property type="entry name" value="pre_pil_HX9DG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="367" mass="40109" checksum="5DA7E90E020C7E5B" modified="2019-10-16" version="1">MDRFQQKASASRSHKRLGFTLVELLVVIAIIGILVGLLLPAVQAAREAARRMQCQNNMKQLGLALHNHMDTYGTLPPGWVNYDESANRYKTGGWQHGQNEMGWHWLAMLLPYVEQPGLWELVEECEAARPTGTQNPCDHCESMDPNHFGREQLPAFSRCPSAVTLSKQFSDGGYGLEALAKGSNYAASWGSGNMLSWESSATRGAFGTYYTTQEKFNTPAVSKADRYQHSKGMGSQDLIDGLSNTVALSEIIGSDGLTGTSSTDIRGVWMSPAMGATIFSAFLNPNSRERDVIAACDEAIPDDRFPLLACIEERDTENVYAAARSFHPGGVNTAMADGSVRFFSETIDNVAVWRPLNTAQNGEVVAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUS3</accession>
    <name>A0A518IUS3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_28390</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021905851" evidence="2">
        <location>
            <begin position="25"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="150" mass="16340" checksum="671AAD04242B2FD5" modified="2019-10-16" version="1" precursor="true">MRPLLSLLLIATFMLGHVVPHSHAASGGAEPGDHAHRPHIHLSHGHDHDHDHGHHHGQADRQSAGEESPAVALTELSLACDHDGDAVYFVDSDWTVARNAVSISLDSSSLPFTSLAGTIPQRERQYRRSSGPPDRRPKLPIYLLTASLRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUY5</accession>
    <name>A0A518IUY5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_28900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="139" mass="15958" checksum="32F27638CB57A86E" modified="2019-10-16" version="1">MHPLLQQIHDEIYSWTYESPAGLMQSAASLLRSVLDSGGPRRDLADFSTLYRLLDGFADQTLDDIFHTLHQWNAAAGSDELNDPESDDNMLSFQVGVVWVMSRSLMLFFNPEEKLETFAEWQEFTFGNIQKMLGMYLRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVF7</accession>
    <name>A0A518IVF7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Type I restriction enzyme EcoKI M protein</fullName>
            <ecNumber evidence="4">2.1.1.72</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">hsdM_2</name>
        <name evidence="4" type="ORF">Mal33_30680</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.1.1.72" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="REBASE" id="355362">
        <property type="entry name" value="M.PbaMal33ORF30680P"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008170">
        <property type="term" value="F:N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009007">
        <property type="term" value="F:site-specific DNA-methyltransferase (adenine-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022749">
        <property type="entry name" value="D12N6_MeTrfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003356">
        <property type="entry name" value="DNA_methylase_A-5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12161">
        <property type="entry name" value="HsdM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02384">
        <property type="entry name" value="N6_Mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HsdM_N" evidence="3">
        <location>
            <begin position="111"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="N6_Mtase" evidence="2">
        <location>
            <begin position="254"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="570"/>
            <end position="591"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV57067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="900" mass="100828" checksum="0DD1148F9A0C70D8" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVK6</accession>
    <name>A0A518IVK6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mercuric transport protein periplasmic component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">merP</name>
        <name evidence="2" type="ORF">Mal33_31200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00371">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00403">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="SSF55008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50846">
        <property type="entry name" value="HMA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMA" evidence="1">
        <location>
            <begin position="52"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="129" mass="13596" checksum="3BE72EEE4051818B" modified="2019-10-16" version="1">MRFMVYVVAVLIAAGIVFVMGKPSETAQQSDPSVASSTTLAVDSGSDVDVQSVALSVPGMHCAFGCYPTVKEALESVDGVQGVELAEQKSETELDNKTVFVTFNNAFKLETALAKLEKAGFDATKIDAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVM6</accession>
    <name>A0A518IVM6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Taurine catabolism dioxygenase TauD, TfdA family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_31430</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042098">
        <property type="entry name" value="TauD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003819">
        <property type="entry name" value="TauD/TfdA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02668">
        <property type="entry name" value="TauD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TauD" evidence="2">
        <location>
            <begin position="30"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="333" mass="36813" checksum="500E6DB72D0066FD" modified="2019-10-16" version="1">MNIAPAPVDKQQTYGDSVFPYALVCSEPGATLAAAADWVGEHRDEILRLANQYGAVLLRDFPVENAEGFDAIIQSLRLENFPYKKSLSNAVRINRTDRVFSANEAPPEVRIFFHHEMAQTPLFPKWIMFSCEIAADQGGATPICRSDVLWQRLAAECPEFAEACEKKGLTYSNVMPNDDDAKSGMGRSWRSTLGVTDREGAEARLRELNYSWEWLEGDSLRATTPPLPAVKDLGEGRKSFFNQMIAAYCGWKDPSNDPSGAIRHADGTPLDGDAVRRAAQLAEELAFDLEWQVGDVVILDNTVAMHARSPFVGTRKVVASLAEMNTHSFTVTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVU4</accession>
    <name>A0A518IVU4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_32070</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd01029">
        <property type="entry name" value="TOPRIM_primases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034154">
        <property type="entry name" value="TOPRIM_DnaG/twinkle"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="382" mass="41959" checksum="483D61A8A4C85878" modified="2019-10-16" version="1">MVSDTPNDEPAGRTRQNDEMRGAVTHDRSPRKRGDSATRHPHLTRRPSIAELKAAMVGRWPEAFHAAAGLPSEHLDGRGYPCFKCGGADRFTAFKDVALRGSVQCRNCFSAGTDPRPGDGIATLRWLLECDTATACRWLTGWLGLTDMAVEFEPPLRRYVPLRSLAKRDGRLDRFADRCHRAMKSDWWSRLETRLGLPSAELIRLRVGWSSQDNATTWPMVDHEDNVVGVRLRCMKSGRKWSVSGGTAGVFMPVGLSPSVDRLFISEGPTDTAALLSIGLDCIGRPSCNGAVAITTKLVKRLHPSEVVIVADDDLNGAGKRGAESLAVALVTVCPRVRIIFPPTGINDAREWVRRGATADDVLPVVHAARVRSLTVRKEVQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVW5</accession>
    <name>A0A518IVW5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SGNH_hydro domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_32230</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021993206" description="SGNH_hydro domain-containing protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="SGNH_hydro" evidence="2">
        <location>
            <begin position="43"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="243" mass="25429" checksum="7D1E1DCD9D889B04" modified="2019-10-16" version="1" precursor="true">MKYLCSLVLFTFAVVVGPVADAADSDVVKPTVGSLPVGRVLYLGNSITLHRPAPKIGWTGNWGMAASAAEKDYVHLLTADIAKASGSQPEIKVRNLASFEREYETFELAKGLKDVLDFQADLVIVAIGENVSTPATDAAKAAFAAAFGQLLATLQQAGDPVIFVRSSFWPSPVKDGIMRQVSSDAGATFVDISALGNDKSYQASAEQDFQHAGVAAHPGDKGMQAIADAIFAAMQAKAGLAGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVZ5</accession>
    <name>A0A518IVZ5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative methyltransferase YcgJ</fullName>
            <ecNumber evidence="3">2.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ycgJ_3</name>
        <name evidence="3" type="ORF">Mal33_32570</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="2">
        <location>
            <begin position="68"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="227" mass="25808" checksum="20A1CA366C510629" modified="2019-10-16" version="1">MEIDVAPAEDETSQQDAPSRSGSKVKAERAQLYKQLAPAYEVLFPLVIRNHIRTSIQSLNIPEGSKVLEVGIGTGISMPVYPQHAKITGIDLSEPMLEVAQKRIQREGWDHFDLRAMNAEQLDFPDESFDFVTAFHVVTVVSKPQKMMAEITRVLKPGGRLLVINHFRSRRKWIANMVDRADSVTRHLGWRTNLECQSIVENLPLEVEHRYKSSPFSLFTIVKAKRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IW03</accession>
    <name>A0A518IW03_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">50S ribosomal protein L18</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">rplR</name>
        <name evidence="9" type="ORF">Mal33_32760</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the universal ribosomal protein uL18 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01337_B">
        <property type="entry name" value="Ribosomal_L18_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005484">
        <property type="entry name" value="Ribosomal_L18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004389">
        <property type="entry name" value="Ribosomal_L18_bac-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12899">
        <property type="entry name" value="PTHR12899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00861">
        <property type="entry name" value="Ribosomal_L18p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00060">
        <property type="entry name" value="L18_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 7 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 7" id="KW-0699">rRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV57272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="122" mass="13487" checksum="6B1F765D6E49093A" modified="2019-10-16" version="1">MDKNKKLDKNRQRRRFHVRNKLRGSADHPRLCVNRSLSHFSCQLVDDINGKTLASASTKDKSLRDGLKFGGNCEAAAAIGKAVAERAVAAGIKRVKLDRGHCKYHGRVKAFAEAAREAGLEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IW55</accession>
    <name>A0A518IW55_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_33230</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039650">
        <property type="entry name" value="HdrA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43498">
        <property type="entry name" value="PTHR43498"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022067573" evidence="1">
        <location>
            <begin position="23"/>
            <end position="1132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1132" mass="121727" checksum="97F106768150A99A" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWD8</accession>
    <name>A0A518IWD8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_33700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SSF49879"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="140"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="258" mass="27932" checksum="954D62A9BFAEC847" modified="2019-10-16" version="1">MAVELSLDNGQRQVFAKNEVTVGCASRCDFVIPPLDGINDTHAVIRRVANRWLIESSGPWQLYPAETPPDTRHWIESAAAIDLAQRGPTLHFRIDPTAAVAAQPQPVSAVQSSQPTPLQAPPQPIATSQPVPVRPSQRPTRPAEFDDRGSPHPDQHGRPFNDPAEGSRSGHASAIPRLGRADTLRRRRSLGFMGFVAEAIKVVLGAAVGLSCSYYIMCRFLPDSALLQIIAAELPANLQPEVIRGEQIGGEQNSDPPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWQ1</accession>
    <name>A0A518IWQ1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_35050</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009599">
        <property type="entry name" value="DUF1207"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06727">
        <property type="entry name" value="DUF1207"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="325" mass="37051" checksum="0C1C76A81B56C8F6" modified="2019-10-16" version="1">MKTWYTLIQQLRRSIRTQRLEQTHALGFLPTTGVKLLILTLAWGCLLDSIPLARADEFDPFATPVAEPLVVLPQWGWHFLPEGLIYHPYLAGPKESRTSVELLKNDDFGWIYDSSIGGQWGFLRVGSDDPYSPTGVQFDLEASAQMRQTNLASLDLLTSDIRVGFPVSFGRNNHQTKLGVYFLRSHPTDRLIDRIPALRNEDFFQRQSLVLGHSRYFAERFRLYGEAGYAFKSTISKKWELQFGAEYAPVMPTSCFGAPFIAANAYLREEVDFGGTLTLQAGWAWRKKNGRLFRIGAQYANGMSNQFALHDRFEQQLGIGIWHDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IX00</accession>
    <name>A0A518IX00_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Fimbrial protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">pilE</name>
        <name evidence="1" type="ORF">Mal33_36300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011453">
        <property type="entry name" value="DUF1559"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07596">
        <property type="entry name" value="SBP_bac_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="333" mass="35910" checksum="B1324BA002286B5E" modified="2019-10-16" version="1">MNKVRTGFTLVELLVVIAIIGILVGLLLPAVQAAREAARRMSCSNNMKQIGLALHNYHDTHSAFPYSVSASGSVESGSATPVAGGVLNHRGWMLLLPFIELQNLQDQIDMNLPTGAYDRASKGLAGPAPGAAGNPNDVAVSTVVDAFLCPSDPNPTQYTSTSSTHYSIAPGSTNLLGAYTNYDFSVRRASNWSSKWTRDTFESRRMFGYDESSKMRDLTDGTSNTAAVCETLRATIDGVSQTWGYSKWVGHGVDLAWSRGINDNECCGWDSPPYQRDTRRSRLGEWATVGSTHPGGAQVTFGDGSVHFLSETTDQVVLNRISYVSDGQPVGDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IX30</accession>
    <name>A0A518IX30_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Inosose isomerase</fullName>
            <ecNumber evidence="2">5.3.99.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">iolI_2</name>
        <name evidence="2" type="ORF">Mal33_36510</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="5.3.99.-" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013022">
        <property type="entry name" value="Xyl_isomerase-like_TIM-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01261">
        <property type="entry name" value="AP_endonuc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="SSF51658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AP_endonuc_2" evidence="1">
        <location>
            <begin position="23"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="272" mass="29602" checksum="0E4F23AE361BF826" modified="2019-10-16" version="1">MPKLSVNELSTYRWSFEEDVFAYAKHGFDSIGIWRAKLAEYGTEKGAELIQENGLRVSSVGWAGGFTGGDGRSFNDSIHDALDAVDLAAQLGAECLIVVSGDRNNHTGSHSRRLLRQALTEVCEAAAALHLDVALEPMHLGAGTQGCFLNNIQNTIDAIGEISWPGLGLVFDSYHLGHDPNLFQWLPDVAPLVRLVQLGDAAHVPMGEQDRLLLGQGKQDLAAIVECFEDAGYDGSFELELIGESIEHLDYDQMLEHSFQALNALVRTPAES</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXB1</accession>
    <name>A0A518IXB1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_37370</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="125"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="241" mass="26811" checksum="E213A0F1D8702585" modified="2019-10-16" version="1">MSDDQTNSEQPTEPKKAQRIYLIPFPKFIFMYPTLLISLLAWAILAIKGYSTVEPDDSLPVMMTGIFLGVLALNTFVIVFDFPRATSLTLIFILTTAALGGWMAVSMKPDLLPAVESWVMALRPAANSTFFGCVSIGMLLMFIAVFVSVRMNYWELSNNELLHHHGILSDLKRYPAPQLRVDKEINDVFEFILLGAGRLILHPAGESRAIVLDNVLFVGNKERLLTQALGSIKVKIGNDSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXD8</accession>
    <name>A0A518IXD8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Cyclic nucleotide-gated potassium channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Mal33_37590</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008076">
        <property type="term" value="C:voltage-gated potassium channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005249">
        <property type="term" value="F:voltage-gated potassium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028325">
        <property type="entry name" value="VG_K_chnl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11537">
        <property type="entry name" value="PTHR11537"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10 14" id="KW-0407">Ion channel</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0630">Potassium</keyword>
    <keyword evidence="5" id="KW-0631">Potassium channel</keyword>
    <keyword evidence="3" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="39"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="100"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="166"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="234"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="Ion_trans" evidence="13">
        <location>
            <begin position="39"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="280"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="280"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="QDV57745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="312" mass="35581" checksum="9548B15B461B2BCD" modified="2019-10-16" version="1">MNVHDHFTRQERRLQCPASGWRRELYIIIFESDTPTGKLFDIGLLIAILVSVAVVSMETVSSVADRYSWYFQALEWSFTILFTAEYLVRLSCVRKPQRYMFSFWGLIDLCSILPTYIFYLAGSHFASVAMVRSIRLLRVFRVLKLLRLMSEADVLYRSIWDSRGKIVVFLFTVVIAVTLSGTLMYQVENFDDHLNNRAPSSSFDSIPQSMYWAIVTMTTVGYGDVVPKTTAGKIISAVLILLGYSLIIVPTGFVTARLSETVHARDRLGNRALADENDDDELKTCQRCGRDDQPSDARYCNQCGEPMPREEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXH7</accession>
    <name>A0A518IXH7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycogen synthase</fullName>
            <ecNumber evidence="3">2.4.1.11</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_37990</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.4.1.11" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004373">
        <property type="term" value="F:glycogen (starch) synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13579">
        <property type="entry name" value="Glyco_trans_4_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="24"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="250"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="450" mass="49518" checksum="70C094E4C629D52D" modified="2019-10-16" version="1">MRIAYLTAGAAGMYCGSCMHDNTLARAMIARGADCLLVPTYTPIRTDEKDISDDVVFFGGINIFLEQKLPLWGRLPHWLTAWLDRPGLLRLATRKTGSTSPHLLGALTVSMLQGMQGRQRTEVDRLCRWLQTHAAPDAIVLSNFLIGGCVTELKRRLGVPVVVTLQGDDIFLDFLPAKYRAMAIDWMRALAADVDGFIVNSRFYGEKMAALLGLPEEKMHVIPLGIDTTGFLSDDSDAPRDPDADASSPLRIGYLARIDPAKGLHRLVDAMIEFERTRQPSDRAIHLDVAGWLGEQHHAYAAEQWARLDRAGLAGRYTYHGSPDHAGKLDFLRRLDLFCVPTEYEEPKGLYALEAMATRLPVILPRHGVFPELAGENSAVHLVPPGDAAALAEAIRTLAGDAASREKLAERGYRSVVGERTVDRMADQVLQLLNDLADGGKPVDHSAARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXH8</accession>
    <name>A0A518IXH8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_38090</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010869">
        <property type="entry name" value="DUF1501"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07394">
        <property type="entry name" value="DUF1501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="480" mass="53066" checksum="86C0DADAA9DB06C4" modified="2019-10-16" version="1">MQNRREFVRQAGTNFGALAMAAMLQRDAQSASGGAVEVLHHPPKAKRVVQLFMAGAASHIDLFDHKPLLEKFHGQESDFGEPVEAFQNGLGPWMKSPFKFARYGKSGKELSEVVAPLGECVDDIAFVHNMVGKTGVHSQATYLQATGFQRPGFPGMGAWVSYGLGAINENLPTFVVLPDHRGFASNGPKNWGSAFLPASAQGTTIFPQRENPIDDLTAQADFVTAAGDRDGLAVLDRMNRRHLQQHAGDSRLEARIRSYELAAAMQLSAPEALDISGETAETMKMYGLDRIGATYPDAINPAEEAEYFGRKCLIARRLLERGVRFVQIWSGNDNGFPRRNWDSHEDIERDHGPLARGMAVGTAALLKDLKRTGMLEDTIVLWTTEFGRMPSTQGSKGRDHNPYVFTNWMSGGGIRGGVSYGESDQWGYKPLDRMHPTQVYDIHATILHQLGIDHKRLTVRHDGVDRRLTDVHGHVIRDLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXR4</accession>
    <name>A0A518IXR4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_38960</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="156"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="257" mass="27059" checksum="FA4671E4B15B7320" modified="2019-10-16" version="1">MPAQGNALGLGSNTNDGGPTPRSRHVTATRRCVWAAVRVGGGACGRRYVWAAVRVSGGTCERRYASAAVRVDAVGVAAAVKRLRPTSFLFDRPNGAGGTSAQGNALGLGSDTNDGGPAPRSRYVTPSRWCVWTRCVWTRGALPPRLNDRAQHRSCWTGPTGRRYASPGRRPGFGERPKRRRPCAAVPSRHGDATVGVGGGGCGRRCASAAVGVDAWGVAAAVKRSRPTWFLFDRPNGPAVCQPRATPWGWGATQTTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXX9</accession>
    <name>A0A518IXX9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">ATP synthase gamma chain</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">ATP synthase F1 sector gamma subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">F-ATPase gamma subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9 10" type="primary">atpG</name>
        <name evidence="10" type="ORF">Mal33_39570</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 9">Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the ATPase gamma chain family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045261">
        <property type="term" value="C:proton-transporting ATP synthase complex, catalytic core F(1)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042777">
        <property type="term" value="P:proton motive force-driven plasma membrane ATP synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12151">
        <property type="entry name" value="F1-ATPase_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00815">
        <property type="entry name" value="ATP_synth_gamma_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035968">
        <property type="entry name" value="ATP_synth_F1_ATPase_gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000131">
        <property type="entry name" value="ATP_synth_F1_gsu"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11693">
        <property type="entry name" value="PTHR11693"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00231">
        <property type="entry name" value="ATP-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00126">
        <property type="entry name" value="ATPASEGAMMA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52943">
        <property type="entry name" value="SSF52943"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01146">
        <property type="entry name" value="ATPsyn_F1gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9" id="KW-0139">CF(1)</keyword>
    <keyword evidence="4 9" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="5 9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV57941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="292" mass="32366" checksum="6FE9F201CBFD0FB5" modified="2019-10-16" version="1">MANARALDKRRKSIRNIRKITRTMELIATARFRKAMDRAAAATDYTERITQIVASLAAAGLEVQHPLLEARPDPRAASCLVLTSNRGLCGGYNSSIFRRALPRIEELRKSMDHLNIDVSGKRGIGAFKFRGIKTNDTYQQFDDQPKFAEVEQIANKYLAAYAAGEIDRLDVVYTKFHSVAKQEAVIETLLPLGAIDLDDEEATGLSADYEFLPSAESILEEVVPTSFKIRLFKCFLDAAVSEQVARMVAMKSATENAGEIIKQLSMTYNRARQSQITGEIMEIIGGVEALAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYD6</accession>
    <name>A0A518IYD6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Carbon dioxide concentrating mechanism protein CcmL</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ccmL</name>
        <name evidence="1" type="ORF">Mal33_41200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031469">
        <property type="term" value="C:bacterial microcompartment"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01614">
        <property type="entry name" value="EutN_CcmL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004992">
        <property type="entry name" value="EutN_CcmL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036677">
        <property type="entry name" value="EutN_CcmL_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36539">
        <property type="entry name" value="PTHR36539"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03319">
        <property type="entry name" value="EutN_CcmL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF159133">
        <property type="entry name" value="SSF159133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51932">
        <property type="entry name" value="BMV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="103" mass="11315" checksum="278C75E3315B3D27" modified="2019-10-16" version="1">MFIARVTGSVVSTQKVASMTGHKLLIVEPYRLEPDQRKSLTTTGRTFIACDTLGAGEGDYVLIVQGSSARLTPETKHLPIDCVIIGIVDSVHIEKQNVYKRDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYG7</accession>
    <name>A0A518IYG7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phosphoribosylformylglycinamidine synthase</fullName>
            <ecNumber evidence="1">6.3.5.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">purQ</name>
        <name evidence="1" type="ORF">Mal33_41500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="6.3.5.3" evidence="1"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004642">
        <property type="term" value="F:phosphoribosylformylglycinamidine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010075">
        <property type="entry name" value="PRibForGlyAmidine_synth_PurQ"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001586">
        <property type="entry name" value="FGAM_synth_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01737">
        <property type="entry name" value="FGAM_synth_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="263" mass="29136" checksum="224C29A0E0832674" modified="2019-10-16" version="1">MAVPRVLILRAPGTNCDEETAFAFEAAGAVTERVHVNRLIENPKLAEDFQVLCLPGGFSYGDDIAAGRILASQLDRHLGDMVRQFCDQDRLVLGICNGFQVLMRLGVLTSGVRETQPATLTWNDHGRFEDRWVHLSVDETPCVFLKGIDKMYLPIAHAEGKFVTTDAEALKAFRDAGRLALRYTTADAGQTSDEVLPFPSNPNGSEANVAGICDATGRLFGLMPHPERHIDPTHHPQWTRRTEQPQWGEGFAIFKNAVDYFGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYJ4</accession>
    <name>A0A518IYJ4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_41800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019600">
        <property type="entry name" value="Hemin_uptake_protein_HemP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10636">
        <property type="entry name" value="hemP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="55" mass="6224" checksum="CB2E31CA57CE8FF5" modified="2019-10-16" version="1">MDSPSDLAHLGETPILPKVFEFAALSGDRPEVWIELDGITYRLRKTRQGKLILTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYL8</accession>
    <name>A0A518IYL8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_41990</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010865">
        <property type="entry name" value="DUF1499"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07386">
        <property type="entry name" value="DUF1499"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="148" mass="16325" checksum="BC5A9478C517A01B" modified="2019-10-16" version="1">MGIAIGAIVLLVTGWIFWQVDDWSRDFTTNHAQLDPAADDPLLRPVLAAESVGQLAARVLSFVETTPHWQVERQRGGPDGTELHLTRTTSLFRYVDDIQVRISPVDGGAQLDAESQSRLGKGDLGQNPRNLKELVRGIDGFPSLQEPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ45</accession>
    <name>A0A518IZ45_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_43750</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="103"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="141"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="173"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="207"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="228" mass="24310" checksum="2C1F8A8B95A3E4AB" modified="2019-10-16" version="1">MAIRVTCEKCLTRFNVSDKFAGKKGPCPKCKATIQIPDKTEEVVVHAPADDGPKDATGKSVLKPIMREEVRVTKLGIFAVAGSIVAAIIAAVVIRSMESVPGWIPPLGALLLAPPLVWSGYTFAREQELEPFYGRELQARVAICSVLFALLWALYAFVPAYVMDYDSVAEMPIGAVLVALAAMLAVGTLISVTTFELETGGGVVHAGFYIVGTLLLAMLAGIPLFAWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ87</accession>
    <name>A0A518IZ87_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative cysteine desulfurase</fullName>
            <ecNumber evidence="2">2.8.1.7</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">csd_2</name>
        <name evidence="2" type="ORF">Mal33_44140</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.8.1.7" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031071">
        <property type="term" value="F:cysteine desulfurase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_5" evidence="1">
        <location>
            <begin position="9"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="376" mass="40870" checksum="053B6EF3413D5A4E" modified="2019-10-16" version="1">MPIALRWAYFDHAAVAPLSEPAQLRMIAFADEAAQTATTLWPYWSKGVESFRSQVARWIGASATEIAMIPNTSHGINLVAEGFPWKSGDNVVTFAGEFPSNRLPWDNQKSKGVEVRTVECPGGEVSLDAIAAQIDDRTRIVAISWVGYASGYRVDLDALAELVHSRGALLFVDAIQAMGIYPIDVAKTPIDFLAADGHKWMLGPEGAGFAYIRSEHLDLLRCTHVGWHSVRNAADFQNAQLNLRPEAARFEAGSANMVGLLALAESAALFEKVIEAHGQDAIANRVLETAETLIQRLEKAGATVLNRWSGENRSSIVVFDVPGVSPAEVRNIGLQQDVVLSCRGGGVRASVHVYNDDQDLDRLIRVVEEARAMPSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZD3</accession>
    <name>A0A518IZD3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_44720</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="103"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="133" mass="14314" checksum="91C28E410164ADEC" modified="2019-10-16" version="1">MTDATNTTTPTVSYRALRNHILWLLIPPTTWAIHFLASYLTIAIVCAKSETGDAMPIQIAIAVYTLVALGAIALVGWHSHRQHRHGDASPPHDGSTSDDQLRFIGYATLLLAALSSVATLFTALVVLFIGSCD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZG4</accession>
    <name>A0A518IZG4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Flavohemoprotein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Flavohemoglobin</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Hemoglobin-like protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Nitric oxide dioxygenase</fullName>
            <shortName evidence="10">NO oxygenase</shortName>
            <shortName evidence="10">NOD</shortName>
            <ecNumber evidence="10">1.14.12.17</ecNumber>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="primary">hmp_1</name>
        <name evidence="10" type="synonym">hmp</name>
        <name evidence="15" type="ORF">Mal33_45020</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>NADH + 2 nitric oxide + 2 O2 = H(+) + NAD(+) + 2 nitrate</text>
            <dbReference type="Rhea" id="RHEA:19469"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16480"/>
            <dbReference type="ChEBI" id="CHEBI:17632"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.14.12.17"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 10">
            <text>NADPH + 2 nitric oxide + 2 O2 = H(+) + NADP(+) + 2 nitrate</text>
            <dbReference type="Rhea" id="RHEA:19465"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16480"/>
            <dbReference type="ChEBI" id="CHEBI:17632"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.14.12.17"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="10">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
        <text evidence="10">Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.</text>
    </comment>
    <comment type="domain">
        <text evidence="10">Consists of two distinct domains; an N-terminal heme-containing oxygen-binding domain and a C-terminal reductase domain with binding sites for FAD and NAD(P)H.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the globin family. Two-domain flavohemoproteins subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.14.12.17" evidence="10"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008941">
        <property type="term" value="F:nitric oxide dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019825">
        <property type="term" value="F:oxygen binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005344">
        <property type="term" value="F:oxygen carrier activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051409">
        <property type="term" value="P:response to nitrosative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.490.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01252">
        <property type="entry name" value="Hmp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008333">
        <property type="entry name" value="Cbr1-like_FAD-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000971">
        <property type="entry name" value="Globin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009050">
        <property type="entry name" value="Globin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012292">
        <property type="entry name" value="Globin/Proto"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023950">
        <property type="entry name" value="Hmp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43396:SF3">
        <property type="entry name" value="PTHR43396:SF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00970">
        <property type="entry name" value="FAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00042">
        <property type="entry name" value="Globin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46458">
        <property type="entry name" value="SSF46458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="SSF52343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01033">
        <property type="entry name" value="GLOBIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0274">FAD</keyword>
    <keyword evidence="10" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5 10 12" id="KW-0349">Heme</keyword>
    <keyword evidence="8 10" id="KW-0408">Iron</keyword>
    <keyword evidence="6 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 10" id="KW-0520">NAD</keyword>
    <keyword evidence="7 10" id="KW-0521">NADP</keyword>
    <keyword evidence="10 15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10 12" id="KW-0561">Oxygen transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 12" id="KW-0813">Transport</keyword>
    <feature type="domain" description="GLOBIN" evidence="13">
        <location>
            <begin position="1"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="14">
        <location>
            <begin position="152"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Reductase" evidence="10">
        <location>
            <begin position="149"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="10">
        <location>
            <position position="95"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="10">
        <location>
            <position position="137"/>
        </location>
    </feature>
    <feature type="binding site" description="proximal binding residue" evidence="10">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="190"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="205"/>
            <end position="208"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="278"/>
            <end position="283"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="399"/>
            <end position="402"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="site" description="Involved in heme-bound ligand stabilization and O-O bond activation" evidence="10">
        <location>
            <position position="29"/>
        </location>
    </feature>
    <feature type="site" description="Influences the redox potential of the prosthetic heme and FAD groups" evidence="10">
        <location>
            <position position="84"/>
        </location>
    </feature>
    <feature type="site" description="Influences the redox potential of the prosthetic heme and FAD groups" evidence="10">
        <location>
            <position position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS01033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="QDV58479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="408" mass="44226" checksum="AF13EAA77DBD669A" modified="2019-10-16" version="1">MLSEKTIEIVKQITPAVAANAETITCKFYQRMFAENPEVKAFFNQAHQHSGGQQKALAGAICAYFSNIDNLEALGPAVELVAQKHCSLGIQPEHYPIVGKHLLAAIKEVMGDGATEEVLGAAGEAYGVLAEICIGRENEIYQQQKSQPGGWNGYRELVVDRKVPESDEVTSFYLTADDGQPLPDHLPGQYITVQIEHPVTPTSPRNYSLSDQPGTGYYRISVKREAGADDDTPGGLISNYLHDAISPGDRISVGPPCGEFTICPMRAADRPVVFLAGGIGITPLLSMAKTLVAAKTEAPIYFLQAARNGNVHALGSEVQELATQGTNVQTRVLYDSPSERDLADKKCDSAGMVSKELIQDWTPFATADFYFCGPKPFMASVHSILKDLGVDDSRMHYEFFGPKAELTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZI9</accession>
    <name>A0A518IZI9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Tetratricopeptide repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_45310</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="267" mass="29855" checksum="087CA13CDE330017" modified="2019-10-16" version="1">MSADASGSPNLDTSVQRRQTLEHCIRDAPADVEPYLELAQIHRALDKPIEAQKVLEKAVRISGDHPEVLWQLEEAELARSLQRLKEFKELHNKHPTPDVTSDLERAQNEWAIRRAEVCRKRLQRDPSQTNLYIVMAEAMYEMGQFAEAAEALEPALNDPQECSKAHLVRGMCLQATNQPLEALASFRGAALRRAVQPAANIKLAALRHAADLSSRLGLRATCKRYLRGILQLNPNDHVATQTLARLEAKGASDIHDLETTENVPSNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZJ3</accession>
    <name>A0A518IZJ3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Methionine gamma-lyase</fullName>
            <ecNumber evidence="5">4.4.1.11</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">mdeA</name>
        <name evidence="5" type="ORF">Mal33_45320</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 3">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the trans-sulfuration enzymes family.</text>
    </comment>
    <dbReference type="EC" id="4.4.1.11" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003962">
        <property type="term" value="F:cystathionine gamma-synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018826">
        <property type="term" value="F:methionine gamma-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019346">
        <property type="term" value="P:transsulfuration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00614">
        <property type="entry name" value="CGS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044639">
        <property type="entry name" value="CGS1/2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000277">
        <property type="entry name" value="Cys/Met-Metab_PyrdxlP-dep_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43379">
        <property type="entry name" value="PTHR43379"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01053">
        <property type="entry name" value="Cys_Met_Meta_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001434">
        <property type="entry name" value="CGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00868">
        <property type="entry name" value="CYS_MET_METAB_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="2">
        <location>
            <position position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR001434-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV58509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="410" mass="45098" checksum="07E6879CD8304EB9" modified="2019-10-16" version="1">MATDTVEQNSEKQTPAKQPPAKQGMSTKSVHAGEDRQKPGDAIADPIFCSSTFTFRTTDDVIDYCEGRSDREEYGRYGNPNERSVERKLAALDCGEAAIVYGSGMAAIVGLLMAKLNAGDEIVFFDQCYHRSREFCSKHLARFGVVTRQVPTGDYDAMEAAINENTRMLVSESPTNPHLTCIDLEQFVALGKAHEVETLIDATLATPYNIQPLEFGVDYVLHSATKYLGGHNDLLAGVIVGSAEALDPVRNLRGIMGAVNSPHNMYLLERGLKTFELRMQRHNANGQAIAEFLESHPRVERVYYPGLKSHPTHEIATQTMRGFGGLVTFTIKDADMRQTANIVDAAKIPRIAPSLGGVESLIEQPLVMSYYKCTPEQRASYGIADNMIRMSCGIENTEDLIADLDQALQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0G8</accession>
    <name>A0A518J0G8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">PhoH-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_48200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003714">
        <property type="entry name" value="PhoH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02562">
        <property type="entry name" value="PhoH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="SSF54791"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PhoH" evidence="3">
        <location>
            <begin position="108"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV58795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="315" mass="34953" checksum="B4A01A48EC1BA029" modified="2019-10-16" version="1">MTEATLSISQPNQILSLFGPRDQNVRLLRERFDVSITHRDGQIRVSGPQEEVRRATQALERLRDQLIRNGVVNQDDLDAVLADDDGSPRSGKIRSGGEIQIRHAGRRIKPRTEGQARYVAAIRKHDLSFCIGPAGTGKTYLAVAMAVEALKAEEVRKIVLVRPAVEAGESLGFLPGDLRAKLNPYLRPLLDALGEMVDYDHSRALMEQDVIEVIPLAYMRGRTLNDAFIILDEAQNTTIAQMKMFLTRLGERSKMVVSGDSTQVDLPRGVQSGLVDAIGRLRNVKGIGLSKLETTDIVRHRLVQEIVNAYEEDKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0T1</accession>
    <name>A0A518J0T1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Na(+)/H(+) antiporter subunit C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">mrpC</name>
        <name evidence="6" type="ORF">Mal33_49740</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039428">
        <property type="entry name" value="NUOK/Mnh_C1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00420">
        <property type="entry name" value="Oxidored_q2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="28"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="72"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV58949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="115" mass="12230" checksum="C933E1C0FB88DE27" modified="2019-10-16" version="1">MDIVLAITVGGLYAAGIYMMMRRSVVKLVIGLGLLSHAANLLIFTAGGVVRGRAPVVPAGEMQPLSEVADPLPQALILTAIVISFAVLAFTLVLVYRTYQTLETDDLDQLKATDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0U4</accession>
    <name>A0A518J0U4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RNA polymerase sigma factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_49850</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014331">
        <property type="entry name" value="RNA_pol_sigma70_ECF_RHOBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02989">
        <property type="entry name" value="Sig-70_gvs1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="2">
        <location>
            <begin position="26"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="186" mass="21421" checksum="6A10B3472069C21F" modified="2019-10-16" version="1">MNLDVTSPCDEQEASRDERFVALVASSQVPLRAFLRTLLRCDADLDDVLQETNMVLWRKRGDYDPTRTFMSWACKIAHLQTLAYWKKHGRQCHQSLSEPLVAEIAAISAQQAEETNEKLALLRSCVQQLNETRRRLLQSRYQKQVSVKQLAEVQGRTAESLAMELFRIRIQLRSCVERKLDAEVAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J108</accession>
    <name>A0A518J108_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HEPN_RiboL-PSP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_50370</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041519">
        <property type="entry name" value="HEPN_RiboL-PSP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18735">
        <property type="entry name" value="HEPN_RiboL-PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HEPN_RiboL-PSP" evidence="1">
        <location>
            <begin position="18"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18735"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="216" mass="23821" checksum="D79765B031BA94F4" modified="2019-10-16" version="1">MSLFEIAREDATARIDGASDLFKTVVKSKDPKSIQRIKGLAFVDMYAAYEPSVLSSVSLYLTAVKDANLPVSRLQPGLQSLIKDPDLQSMTESKKVKWKRRSEMLAKLQSGLTGCAVVSVFPDDGSHYRMSQLHLIWDLLQLRGSVLPAKMLTPLIGEVVENRNAIAHGRERPETIGRRYTEVEIQEKLDQVKTICIHILTAAENGAISAVTAASV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1G2</accession>
    <name>A0A518J1G2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Arylsulfatase</fullName>
            <ecNumber evidence="6">3.1.6.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">atsA_36</name>
        <name evidence="6" type="ORF">Mal33_51860</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="PTM">
        <text evidence="3">The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the sulfatase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.6.1" evidence="6"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004065">
        <property type="term" value="F:arylsulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024607">
        <property type="entry name" value="Sulfatase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00523">
        <property type="entry name" value="SULFATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00149">
        <property type="entry name" value="SULFATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021975791" evidence="4">
        <location>
            <begin position="32"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase" evidence="5">
        <location>
            <begin position="39"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="modified residue" description="3-oxoalanine (Cys)" evidence="3">
        <location>
            <position position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR600917-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV59158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="494" mass="54582" checksum="CC236E26CE9A3824" modified="2019-10-16" version="1" precursor="true">MPRTLLNACIALALYLAAHTLPLPLTNTVDAAADEKRPPNFIIIYCDNLGYGDIEPFGSTLHRTPNLNRMARQGRKFTHFCVTAGVCTPSRSSIITGCYSQRVGMHMNPRDGWVLRPVSRYGLNPEEQTIAEVLKQQGYATAMVGKWHLGDQPQFMPTRQGFDWFFGVPYSDDMTERVWDKDGSQWPPLPLMENDTVIEAPCDRDGLTKRYTEKAMEWIAEHKDEPFFLYFPQAMPGSTSTPFSSDAFRGKSKNGPWGDSIEELDWSMGQMLDQLEELGIAENTLVVWTSDNGAPINRNPADLSRGSNLPLHGRGYTTSEGAFRVPTIVWQPGKVPAGSVCEELATTMDLLPTFAKLAGGAPPTDRKIDGHDIAPLLYGEAGATTPYKAFYYYHQDQLHAVRSGEWKLFLPEAKVSGHPHFSSKLPPQPLLFNVVTDIGCDKNVAAEHPEIVARLSQLADEARADLGDLGVAGAGQRQRGELAKGVEPVPQLLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1H0</accession>
    <name>A0A518J1H0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="11">ATP-dependent RNA helicase RhlE</fullName>
            <ecNumber evidence="11">3.6.4.13</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">rhlE</name>
        <name evidence="11" type="ORF">Mal33_52050</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the DEAD box helicase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="11"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6 11" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 6 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Q_MOTIF" evidence="10">
        <location>
            <begin position="2"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="8">
        <location>
            <begin position="33"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="9">
        <location>
            <begin position="219"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="368"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="5">
        <location>
            <begin position="2"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="378"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="393"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="424"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QDV59177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="466" mass="50733" checksum="3FC90A18C5985750" modified="2019-10-16" version="1">MKTFQELDLIAPLQRALADENYEIPTPIQAQTIPAALDERDVLGCAQTGTGKTAAFALPILNRLGSQPRKTQPGRPAVLVLAPTRELAIQIGDSFATYGKHLKLRHALVYGGVGQHKQVRDMQRGVHVLVATPGRLLDLMTQGHIQLDRLEVFVLDEADRMLDMGFLPDLKRIISKLPSRRQSLFFSATMPPKIVELTQRLLHDPVSVNVTPKTTSVERIEQRVIFAERSDKQSMLRKILSGDDVDRAIVFTRTKRGANTLAEKLVKSGIASAAIHGNKSQGARQRALEAFRTRQVQVLVATDVAARGIDIDGVTHVVNFDMPTEPESYVHRIGRTGRAGADGLAVSFCTAAERGELHAIEKLIGQKLQVSGEQPKPVSAAERHEMRTNSRRPSGSRRSNGPRSATPASGQPRSVKPRSNKRPAAAGQGNSQQTGAAAVIAAAKNAAKPKAKKKRVRPASMWAEVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1Q9</accession>
    <name>A0A518J1Q9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Class III signal peptide</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_53050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007166">
        <property type="entry name" value="Class3_signal_pept_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04021">
        <property type="entry name" value="Class_IIIsignal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="117" mass="12028" checksum="A9F0ECF012815691" modified="2019-10-16" version="1">MSKRIAPRKNRRGQGLVEYIIIVAAVALIALVAVSIFGHKVADQYAIGAGMLPGAHAEDNAPIVTGEYAEFADDGNGANIGNGRVSWDSVTGNATAGEMKNNVVTAASNAAEAFVAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J216</accession>
    <name>A0A518J216_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_54200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="145"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="253" mass="26760" checksum="EC1ED7C19995D724" modified="2019-10-16" version="1">MRFPNLAIPRLIVATVVVAVQGVACGADWLTLPSTYTHDPSTGARVDQYAAKAPAVSRVDPTYRESGYRQYRSTLQYGQAADNYHSVEKWGEPVRPYGEWRFPVRPYSAPYSAWGAPLAGMNVGGYYPGWQGGYPNPGYNGGGYPHGGGHPHGQHNGGNGNGHHGGNHPGGGQSGGAYPGGGHSGGGYHGGGHPGGGSGYPGGYAQPGFGGASLTPYPPTQAYPTPPYYDGSYPTYGEQPRMNDREFYRKPRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J240</accession>
    <name>A0A518J240_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytochrome c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Mal33_54380</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002327">
        <property type="entry name" value="Cyt_c_1A/1B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013427">
        <property type="entry name" value="Haem-bd_dom_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013428">
        <property type="entry name" value="Membrane-bound_put_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011041">
        <property type="entry name" value="Quinoprot_gluc/sorb_DH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11961">
        <property type="entry name" value="PTHR11961"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00034">
        <property type="entry name" value="Cytochrom_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50952">
        <property type="entry name" value="SSF50952"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02603">
        <property type="entry name" value="CxxCH_TIGR02603"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02604">
        <property type="entry name" value="Piru_Ver_Nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="3 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Cytochrome c" evidence="6">
        <location>
            <begin position="853"/>
            <end position="985"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV59403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="988" mass="108586" checksum="CC412BA5D565977B" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J253</accession>
    <name>A0A518J253_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DNA adenine methyltransferase YhdJ</fullName>
            <ecNumber evidence="6">2.1.1.72</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">yhdJ</name>
        <name evidence="6" type="ORF">Mal33_54520</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the N(4)/N(6)-methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.72" evidence="6"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="REBASE" id="357091">
        <property type="entry name" value="M.PbaMal33ORF54520P"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008170">
        <property type="term" value="F:N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009007">
        <property type="term" value="F:site-specific DNA-methyltransferase (adenine-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002941">
        <property type="entry name" value="DNA_methylase_N4/N6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001091">
        <property type="entry name" value="RM_Methyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01555">
        <property type="entry name" value="N6_N4_Mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00508">
        <property type="entry name" value="S21N4MTFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N6_N4_Mtase" evidence="5">
        <location>
            <begin position="25"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="268"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="276"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="306"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="362"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="480"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="496"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="553"/>
            <end position="569"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV59417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="662" mass="71232" checksum="FF8F24A7EC07D0A0" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ILV4</accession>
    <name>A0A518ILV4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">VWA domain containing CoxE-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_00100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002881">
        <property type="entry name" value="DUF58"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01882">
        <property type="entry name" value="DUF58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF58" evidence="1">
        <location>
            <begin position="48"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="319" mass="36083" checksum="D45CCFB3DD229D04" modified="2019-10-16" version="1">MSASSNDAPAQIDPSSLMRIKNLQLRAKTVVEGFYNGLHRSPFHGFSVEFSEYRPYTLGDDPRTLDWKLFARSDRYYIKRYEDETNRRCYLMVDQSKSMGFGSLDYTKADYTRTLAATLAHFLTQQRDAVGLMTFDRKVNEFIAARHRPGHMNRLLGSLDQSFEGTGTDLSEPLEQLAALVSKRGLIILISDLLAPIDMLRTRLAYLRSRGHEMMILRVNDPAEIEFTLPQAAMIRDMETGKELYIDPEVAKAQYQANFKEHETQLVAICESLGIDLTQLVTNQPMDEALYQLLSLQTRRSRGPQRGGSLSAAARGAAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ILX4</accession>
    <name>A0A518ILX4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Multidrug resistance protein NorM</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">norM</name>
        <name evidence="2" type="ORF">Mal33_00390</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="120"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="158"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="193"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="219"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="281"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="310"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="344"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="389"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="417"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="447"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="496" mass="53239" checksum="A23D00FCB10795D0" modified="2019-10-16" version="1">MLHKVNQTERFPERNHWMLLNSRKMRPDPFRYRALLAVALPLAATVGCFSITLFTDRTLLMWYGPTSAAASVSAGNLYWAVVCIPVTAMGFLTPLVAMAMGNKRRRGAMIGRVWSLVWQCLWLTLLFIPLLALIGWVAPAIFAAFGHPEDLAQQEARYFRTLLLVAPASMLEAGLTAFFVGRRVTRPILRANIASAVLNVLLDFWFIFGGIGLPAMGVFGAALATAVAMWCKVAIFAVLLLRLQSFGRHRPQAWRPNLQLIREIIVPGSTLGIQQLVRSSLFSFILLVIGAASVQGLAATSAALSLYQLLSIPAIGLATAVTVLTGQAYASAGIAPALQVIRRSAIVGAAVALSLAATLWSFPDALLQIPLGGLPADQRQDLQPLAAQLLAYAAVYGIVDISSLVLGAAIKGIGKTFIVLFATALPGFISVVVGWTFAPTDASAVPYWWTVLILWAAFQAAIIGLGIARAVRKSQQPRSAEAINKSSLSTIATKPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IM28</accession>
    <name>A0A518IM28_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribonuclease 3</fullName>
            <ecNumber evidence="6">3.1.26.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Ribonuclease III</fullName>
            <shortName evidence="6">RNase III</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 11" type="primary">rnc</name>
        <name evidence="11" type="ORF">Mal33_00950</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>Endonucleolytic cleavage to 5'-phosphomonoester.</text>
            <dbReference type="EC" id="3.1.26.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ribonuclease III family.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.3" evidence="6"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004525">
        <property type="term" value="F:ribonuclease III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00104">
        <property type="entry name" value="RNase_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014720">
        <property type="entry name" value="dsRBD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011907">
        <property type="entry name" value="RNase_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000999">
        <property type="entry name" value="RNase_III_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036389">
        <property type="entry name" value="RNase_III_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11207">
        <property type="entry name" value="PTHR11207"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00035">
        <property type="entry name" value="dsrm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14622">
        <property type="entry name" value="Ribonucleas_3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00358">
        <property type="entry name" value="DSRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00535">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69065">
        <property type="entry name" value="SSF69065"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02191">
        <property type="entry name" value="RNaseIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50137">
        <property type="entry name" value="DS_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00517">
        <property type="entry name" value="RNASE_3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50142">
        <property type="entry name" value="RNASE_3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="6 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="6" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="6" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="RNase III" evidence="10">
        <location>
            <begin position="67"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="DRBM" evidence="9">
        <location>
            <begin position="218"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="267"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="109"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="180"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QDV54149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="297" mass="32458" checksum="C5CF52E6E3B4A85B" modified="2019-10-16" version="1">MNAEPHRPQDDRPSIAPPPPPANSDCDDATLLAAPATTAAKPTKAKAAKAAAAIDSDNEELTTEQRLDLCESIIGHSFSDRELLLEALTHASGASHRLKSNERMEFLGDAILGAVVCDWLYHERTDLNEGELTKIKSNVVSRQTCSKVAKRLGLDRCLLVGKGVRKNRSFPKSLTSDVFESIVAAIYLDGGFDKVRELLHQWLAQEVAEGINSRGDENHKSNLQQVVQRDFSTTPCYRLLDSVGPDHSKKFQIAVLVDGQLRTPAWGRSKKDAEQRAAANALAEISGKEPPYQDGLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IM68</accession>
    <name>A0A518IM68_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">TPR_21 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_01100</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="TPR-like_helical_dom_sf"/>
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        <property type="entry name" value="TPR_21"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09976">
        <property type="entry name" value="TPR_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="28"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="domain" description="TPR_21" evidence="4">
        <location>
            <begin position="28"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="207"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="235"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF09976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV54163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="268" mass="29013" checksum="4FE892B7FD8313EB" modified="2019-10-16" version="1">MKSEERHQLQQNELADALGSGIQSITPYLRAIVIGVIGLIVIVFAYNFVSMRKQAHDATASLDFLLATSNEDPESFKRVSQDFADTMPGQWAQIAQADHNLGAGIESMFVDRDEATGFLEAATENYKSVLATAKDPLLKTRANLGLAKAYEAQGDLDQAIATYEIVADNTSSEALAEQAKERIRLLGTDDVRDFYTWFRENQPVSMASIAPGLPGLEDLPDGPTDGLPPAETPDLKDVEVSDAPEAEAKEEAAAAPKEEATEEPAKTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMI6</accession>
    <name>A0A518IMI6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acetylornithine deacetylase</fullName>
            <ecNumber evidence="3">3.5.1.16</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">argE_1</name>
        <name evidence="3" type="ORF">Mal33_02460</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.5.1.16" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008777">
        <property type="term" value="F:acetylornithine deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001261">
        <property type="entry name" value="ArgE/DapE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00758">
        <property type="entry name" value="ARGE_DAPE_CPG2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00759">
        <property type="entry name" value="ARGE_DAPE_CPG2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="M20_dimer" evidence="2">
        <location>
            <begin position="189"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="394" mass="42763" checksum="A8BC97035E57EC1B" modified="2019-10-16" version="1">MIASKTPLSILIQLIAIPSQNPMGHEPVGDGWYEAGVSRWLCEFFKEHSLPYEYHEIESQRGNVVARIDGDPNRPTILLDAHQDTVPVAGMIVDPYDAIEKEGRLYGRGTCDVKGSIAAMLATALRLIPLNGDHAPVILSFTCDEERTQIGAAELARRLALPAAQRSALLPENPQFAIVCEPTDLNVVVAHKGTVRWKIRTSGAAAHSSNPALGVNAIYKMAKIVSCLETYAAELQSGGIVHPLCGGRTLSVGTIHGGASVNIVPEQCTIEIDRRLVPGEVAEEAIAAVDQYLRENCDVDFEFLPIDTISNPLLDRDNAALCQRLIEAAEPTRANRQAIGVPFGTHAPRIAALEIPTVVFGPGSIDQAHTKDEWIEIQQLDEAVDIFVRLLTKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMJ4</accession>
    <name>A0A518IMJ4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">Multifunctional fusion protein</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="7">Peptide methionine sulfoxide reductase MsrA</fullName>
                <shortName evidence="7">Protein-methionine-S-oxide reductase</shortName>
                <ecNumber evidence="7">1.8.4.11</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="7">Peptide-methionine (S)-S-oxide reductase</fullName>
                <shortName evidence="7">Peptide Met(O) reductase</shortName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="6">Peptide methionine sulfoxide reductase MsrB</fullName>
                <ecNumber evidence="6">1.8.4.12</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="6">Peptide-methionine (R)-S-oxide reductase</fullName>
            </alternativeName>
        </domain>
    </protein>
    <gene>
        <name evidence="11" type="primary">msrAB</name>
        <name evidence="7" type="synonym">msrA</name>
        <name evidence="6" type="synonym">msrB</name>
        <name evidence="11" type="ORF">Mal33_02560</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>[thioredoxin]-disulfide + H2O + L-methionine = [thioredoxin]-dithiol + L-methionine (S)-S-oxide</text>
            <dbReference type="Rhea" id="RHEA:19993"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:58772"/>
            <dbReference type="EC" id="1.8.4.11"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 6">
            <text>[thioredoxin]-disulfide + H2O + L-methionyl-[protein] = [thioredoxin]-dithiol + L-methionyl-(R)-S-oxide-[protein]</text>
            <dbReference type="Rhea" id="RHEA:24164"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="Rhea" id="RHEA-COMP:12313"/>
            <dbReference type="Rhea" id="RHEA-COMP:12314"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16044"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:45764"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.8.4.12"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 7">
            <text>[thioredoxin]-disulfide + H2O + L-methionyl-[protein] = [thioredoxin]-dithiol + L-methionyl-(S)-S-oxide-[protein]</text>
            <dbReference type="Rhea" id="RHEA:14217"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="Rhea" id="RHEA-COMP:12313"/>
            <dbReference type="Rhea" id="RHEA-COMP:12315"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16044"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:44120"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.8.4.11"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the MsrA Met sulfoxide reductase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the MsrB Met sulfoxide reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.8.4.11" evidence="7"/>
    <dbReference type="EC" id="1.8.4.12" evidence="6"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033744">
        <property type="term" value="F:L-methionine:thioredoxin-disulfide S-oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033743">
        <property type="term" value="F:peptide-methionine (R)-S-oxide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008113">
        <property type="term" value="F:peptide-methionine (S)-S-oxide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030091">
        <property type="term" value="P:protein repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01401">
        <property type="entry name" value="MsrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01400">
        <property type="entry name" value="MsrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002569">
        <property type="entry name" value="Met_Sox_Rdtase_MsrA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036509">
        <property type="entry name" value="Met_Sox_Rdtase_MsrA_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028427">
        <property type="entry name" value="Met_Sox_Rdtase_MsrB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002579">
        <property type="entry name" value="Met_Sox_Rdtase_MsrB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10173">
        <property type="entry name" value="PTHR10173"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01625">
        <property type="entry name" value="PMSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01641">
        <property type="entry name" value="SelR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="SSF51316"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55068">
        <property type="entry name" value="SSF55068"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00401">
        <property type="entry name" value="msrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00357">
        <property type="entry name" value="TIGR00357"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51790">
        <property type="entry name" value="MSRB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="4 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="domain" description="MsrB" evidence="10">
        <location>
            <begin position="245"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="219"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="224"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="6">
        <location>
            <position position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QDV54306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="382" mass="43031" checksum="99B0EAF65A7E0AE4" modified="2019-10-16" version="1">MTTQRTLFSLIPLLAIAGFSVWLIASDRSSSSHKQPVIPANAKVETAIFAGGCFWCMEPPFEKQPGVIAAESGYTGGHKKNPTYEEVSHTETGHVEAVRVTFDANQIAYSDLLEIFWRNIDPTDRYGQFVDQGSSYTSAIFVANDAQREQATASKQQLIESGRFEKEIVTPIQDASTFYLAEDYHQDYYKKNPLRYSFYRRMSGRDEFIDAAWGDDRNYHPKTKATAPGSTDSAAASSRYSRPSETVLRDQLTDLQYRVTQQDATEPPFKNTYWDNKQAGIYVDVVSGEPLFSSKDKFKSGTGWPSFTRPLVRDNVLEQTDYKLFLPRTEVRSKHGNSHLGHVFSDGPEPTGLRYCLNSAALRFIPADELEAQGYSEFAESF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMT4</accession>
    <name>A0A518IMT4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptidyl-prolyl cis-trans isomerase</fullName>
            <ecNumber evidence="5">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">mip</name>
        <name evidence="7" type="ORF">Mal33_03540</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 4 5">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the FKBP-type PPIase family.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.460">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000774">
        <property type="entry name" value="PPIase_FKBP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036944">
        <property type="entry name" value="PPIase_FKBP_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01346">
        <property type="entry name" value="FKBP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase FKBP-type" evidence="6">
        <location>
            <begin position="159"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV54400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="253" mass="27147" checksum="AF90F4592F71EAD9" modified="2019-10-16" version="1">MKRLLFCGLLCSCLSTLPIQDAMSQDSIPAPASGVKDVNSYALGLEMGSQLRRQGFEAGDLDTASVALGIFDAISKANPKITTEQIQAAFQAIDAQLQQRAEARIREQEKKMEAIAGPNKEKADAFLAANGKKPGVVTLPSGLQYQVIKEGTGASPTAQSTVSVHYTGKLINGEVFDSSVQRGQPAQFGVGQVIRGWTEGLQKMKVGDKWMLYIPPDLGYGLRGSPSRDPNEPPTIGPNEALIFEVELLDILD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMV7</accession>
    <name>A0A518IMV7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nickel-containing superoxide dismutase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_03700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016151">
        <property type="term" value="F:nickel cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004784">
        <property type="term" value="F:superoxide dismutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.400">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036502">
        <property type="entry name" value="NiSOD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014123">
        <property type="entry name" value="Superoxide_dismutase_Ni-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09055">
        <property type="entry name" value="Sod_Ni"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109770">
        <property type="entry name" value="SSF109770"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022179590" evidence="1">
        <location>
            <begin position="23"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="152" mass="17153" checksum="B077CDBD9E089606" modified="2019-10-16" version="1" precursor="true">MRNTIYLAMAMLLAFTAKSASAHCEVPCGIYDDERRFVSMIEDHSTIEKAIAQIDELAGKHDAQDLNQLVRWVTTKEDHATRIQQTIAQYFMTQRLKADGENYTKKLTTAHAVMVAAMKCKQTAAPDSAVALKKAIHDFYRAYEGKEPHLHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ING0</accession>
    <name>A0A518ING0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_05750</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022136527" evidence="1">
        <location>
            <begin position="24"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="160" mass="18332" checksum="D0FD694D1B0792E2" modified="2019-10-16" version="1" precursor="true">MHQIAFATILVLCSSIFSPTALAGRSITLFNEIDEKTGHDNHMVAVELFGDRAEITYCHGTDVVDILPLIRFLQDGSDHAITLRRVHIREIDVERRGWVIVWIFNRIKDSAPSILVYSSNDVSQRTAMSIGRSFRAMRKVPVVYRSRDELMEFYTDETTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INK4</accession>
    <name>A0A518INK4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DNA-binding protein HU</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">hup</name>
        <name evidence="3" type="ORF">Mal33_06290</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial histone-like protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000119">
        <property type="entry name" value="Hist_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010992">
        <property type="entry name" value="IHF-like_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33175">
        <property type="entry name" value="PTHR33175"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00216">
        <property type="entry name" value="Bac_DNA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01727">
        <property type="entry name" value="DNABINDINGHU"/>
    </dbReference>
    <dbReference type="SMART" id="SM00411">
        <property type="entry name" value="BHL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47729">
        <property type="entry name" value="SSF47729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="115"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="150" mass="16693" checksum="3AA781A408B43300" modified="2019-10-16" version="1">MQRTYNAESSVLGIEFVTKKDIVKTISEEVGLTQQQTKKIVQKTFDAIIDSLVKEERIELRNFGVFEVKLRAARKARNPRTGKQVSVPAKYVVTFKPGKEMESRVAELTAGIVENHQTESELGSLGRTDESLNKPADPTTHDAFGDRSVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INM4</accession>
    <name>A0A518INM4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NAD-dependent malic enzyme</fullName>
            <ecNumber evidence="5">1.1.1.38</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_06440</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="3">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="3">Divalent metal cations. Prefers magnesium or manganese.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the malic enzymes family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.38" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004471">
        <property type="term" value="F:malate dehydrogenase (decarboxylating) (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008948">
        <property type="term" value="F:oxaloacetate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd05311">
        <property type="entry name" value="NAD_bind_2_malic_enz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminiacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012301">
        <property type="entry name" value="Malic_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037062">
        <property type="entry name" value="Malic_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012302">
        <property type="entry name" value="Malic_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045213">
        <property type="entry name" value="Malic_NAD-bd_bact_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001891">
        <property type="entry name" value="Malic_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13291">
        <property type="entry name" value="ACT_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00390">
        <property type="entry name" value="malic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03949">
        <property type="entry name" value="Malic_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000106">
        <property type="entry name" value="ME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01274">
        <property type="entry name" value="malic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00919">
        <property type="entry name" value="Malic_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="SSF53223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ACT" evidence="4">
        <location>
            <begin position="10"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="112"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="167"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="209"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="210"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="235"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000106-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000106-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV54688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="475" mass="50328" checksum="365CFFBB6240AA50" modified="2019-10-16" version="1">MDQTFSYSATIRLTYANDRGMLGRIATAIGEQGGMIGAIDIVSSSGKGITRDVSVNAANAEHVQRIAEHLETIPGLELQTVSDQVFLKHLGGKIEVVAKTPIKSRDDLSSVYTPGVARVCMAIHDDVESSYSLTIRKNMVAVVSDGSAVLGLGNIGPEAAMPVMEGKAMLFKEFGGVDAFPICIATQDVEEIIATVQRLEPTFGGINLEDISSPRCIEIERRLNETMDIPVFHDDQHGTAIVTLAGLENALRLVQKKLSEVKIVINGAGAAGAAIAKLLQLAGAEHVIVCDREGAIYAGRTTRMNPVKDELAAVTNKDGLQGSLRDVVRGADVFVGVSSPDVLTVDDVKSMAAEPIVFAMANPDPEIRPELANGHVAVMATGRSDHPNQINNVLCFPGLFRGVLDVRASEVNDAMKVAAAKAIADIITDDERCSDYIIPSVFDRRVAAAVAKAVADAAAETGVARRRPKNSAVGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INP0</accession>
    <name>A0A518INP0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8 10">FAD:protein FMN transferase</fullName>
            <ecNumber evidence="2 8 10">2.7.1.180</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Flavin transferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">apbE_1</name>
        <name evidence="12" type="ORF">Mal33_06540</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8 10">
            <text>FAD + L-threonyl-[protein] = AMP + FMN-L-threonyl-[protein] + H(+)</text>
            <dbReference type="Rhea" id="RHEA:36847"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11061"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:74257"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.7.1.180"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="9">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="9">Magnesium. Can also use manganese.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8 10">Belongs to the ApbE family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.180" evidence="2 8 10"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017013">
        <property type="term" value="P:protein flavinylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024932">
        <property type="entry name" value="ApbE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003374">
        <property type="entry name" value="ApbE-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30040">
        <property type="entry name" value="PTHR30040"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02424">
        <property type="entry name" value="ApbE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006268">
        <property type="entry name" value="ApbE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143631">
        <property type="entry name" value="SSF143631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0274">FAD</keyword>
    <keyword evidence="4 8 10" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="12" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="7 8 9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8 10" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="296"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="300"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR006268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR006268-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QDV54697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="357" mass="38581" checksum="C261A9D84416D886" modified="2019-10-16" version="1">MKNVLQPKSNSAANPLNNAASPSENSPSIARPGELISVIRPAMATEFEVLMPADVDREAPEIALEALEWIRTLEGIFSVYRSDSDISKLNREAAERPVRVDPHLFKIVQQAIAISDATGGAFDITAGPLVDAWGFTNRSGRKPSDEELAAALQAVGYQNLELDADQQTIRFKQPEMRINLGAIGKGYALDQAVAMLVTSGVENFLIHGGQSSIVARGSRRPGEPGWPIALSHPIRSHRKLGRVWLQNESLSTSGSGKQFFHYRGQRLGHMIDPRTGWPGGDLLSLTLIAKVAAESDALATGLFVDGMPQATQFVEANPGLGIVGVAEVDRSSEVEVVAVAIADERWEPFQESSRDLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INX8</accession>
    <name>A0A518INX8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">6-carboxy-5,6,7,8-tetrahydropterin synthase</fullName>
            <ecNumber evidence="5">4.1.2.50</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Queuosine biosynthesis protein QueD</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">queD</name>
        <name evidence="11" type="ORF">Mal33_07560</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>7,8-dihydroneopterin 3'-triphosphate + H2O = 6-carboxy-5,6,7,8-tetrahydropterin + acetaldehyde + 2 H(+) + triphosphate</text>
            <dbReference type="Rhea" id="RHEA:27966"/>
            <dbReference type="ChEBI" id="CHEBI:15343"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18036"/>
            <dbReference type="ChEBI" id="CHEBI:58462"/>
            <dbReference type="ChEBI" id="CHEBI:61032"/>
            <dbReference type="EC" id="4.1.2.50"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Purine metabolism; 7-cyano-7-deazaguanine biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the PTPS family. QueD subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.50" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00391"/>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070497">
        <property type="term" value="F:6-carboxy-5,6,7,8-tetrahydropterin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007115">
        <property type="entry name" value="6-PTP_synth/QueD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038418">
        <property type="entry name" value="6-PTP_synth/QueD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12589">
        <property type="entry name" value="PTHR12589"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01242">
        <property type="entry name" value="PTPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 11" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00018141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QDV54791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="142" mass="16350" checksum="C2E690B0DC682984" modified="2019-10-16" version="1">MGLTVMRRIRFCAGHRLVGHDGKCVHFHGHNYVAEFYVTGEVQDDVGRIIDFGVLKRKFKGWIDENWDHAFVLWDQDTNGLQAIRMVEPCRVFELPYNPTSENMARYLLEVVCPELLHDTGTHANKVVIWESEESCSEVTLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP71</accession>
    <name>A0A518IP71_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Protocatechuate 3,4-dioxygenase alpha chain</fullName>
            <ecNumber evidence="5">1.13.11.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">pcaG</name>
        <name evidence="5" type="ORF">Mal33_08450</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the intradiol ring-cleavage dioxygenase family.</text>
    </comment>
    <dbReference type="EC" id="1.13.11.3" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008199">
        <property type="term" value="F:ferric iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018578">
        <property type="term" value="F:protocatechuate 3,4-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006725">
        <property type="term" value="P:cellular aromatic compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03459">
        <property type="entry name" value="3_4-PCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039387">
        <property type="entry name" value="3_4-PCD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000627">
        <property type="entry name" value="Intradiol_dOase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015889">
        <property type="entry name" value="Intradiol_dOase_core"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00775">
        <property type="entry name" value="Dioxygenase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49482">
        <property type="entry name" value="SSF49482"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="3 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="INTRADIOL_DIOXYGENAS" evidence="4">
        <location>
            <begin position="63"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV54880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="250" mass="27442" checksum="83BB1A2F8077D229" modified="2019-10-16" version="1">MLHAVLNLNMTSASAKLGPTIMHNPSTRFPLSRRSLLAVGGAAFFATPGLFAEQLQSTPPLTEGPFYPDKLPLDQDNDLILINDSTTPAVGQITHLTGRVLTPAGSPVRNATIEIWQCDANAVYLHSRDSNGKKKQQDPNFQGFGRFETGAMGEYRFRTIKPVEYPGRPAPHIHIIVKQNDRKVLTTQLMIRGYAGNARDGVFRRITDPAKRELLVADFNPVPESKIGEFACHFDVVLGRTPGDAGKQRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPH3</accession>
    <name>A0A518IPH3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cyclic di-GMP phosphodiesterase response regulator RpfG</fullName>
            <ecNumber evidence="2">3.1.4.52</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rpfG_1</name>
        <name evidence="2" type="ORF">Mal33_09640</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.4.52" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071111">
        <property type="term" value="F:cyclic-guanylate-specific phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037522">
        <property type="entry name" value="HD_GYP_dom"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51832">
        <property type="entry name" value="HD_GYP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD-GYP" evidence="1">
        <location>
            <begin position="125"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="402" mass="45100" checksum="930B43DF15E20920" modified="2019-10-16" version="1">MSLDVEKLVVGTVLKESLYSDSGQLLLRRGSYVSEEVYKRLRRRSASRIVAPPPVSLDSYAAGLPGSDASRHGCKPYDDRQVQRLQQRFESAAETVTDLADAFNQRKLKSAQGLRDLAGDCIDDMSNDMDQVLSAMCEVPEDHRLAARCMRMGMICVAIGMEMDLPKDELIQVGTAGVVHDWGLFSLPPELRYIHPEMTFQQRIQYTRHPFYAHDLLRAISNVDGSVLLAVLQAHERIDGSGFPSGLRGDPICLFARILAVADTYLALTAPVGDLPAVVPCDAVAYLVGQLGKSRFDPRVVRGFLQSMAQFPIGSLLQLNDHRQVKVLRSNGKQYGRPIVQDLMSSEILDLAQHDLDIVKPILRHDPSEYRLKPEFRRLMDNRDLPEYLHKDCFVRPEMVDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPR7</accession>
    <name>A0A518IPR7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ski2-like helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_10290</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="2">
        <location>
            <begin position="32"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="3">
        <location>
            <begin position="224"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="509"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="546"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="670"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="547"/>
            <end position="561"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV55060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="824" mass="92451" checksum="EF72791CBDA1E34D" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPW3</accession>
    <name>A0A518IPW3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/beta hydrolase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_10970</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008391">
        <property type="entry name" value="AXE1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009199">
        <property type="entry name" value="PhoPQ-act_pathogen-rel_PqaA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05448">
        <property type="entry name" value="AXE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10142">
        <property type="entry name" value="PhoPQ_related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022189039" evidence="1">
        <location>
            <begin position="21"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="domain" description="AXE1" evidence="2">
        <location>
            <begin position="86"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="424" mass="46221" checksum="1390193B1B8F5028" modified="2019-10-16" version="1" precursor="true">MKRSFALMLVLLLPPVLLTAQDAKDENVSQALTAMVASAKQTPEMRWVDQTGPVHSLQYAGEDYRGKPTEVFAFYASPTTLGEGTADAKYPAVVLIHGGGGTAFAEWVWLWAKRGYAAIAMDLGGSRPSAPKFNPETGVPIANQGYPANTRTRLENGGPNQGHVEKFDSIGGEVSDDWPFHAAASVLRAHSLIRSFDDVDAERTAVTGISWGGYTTCLAASLDDRFKAAVPVYGCGFLHEGESVQKPSIDRLGDRRDDWVAVYDPGSQLRHCRVPILFVNGTNDVHYPLDSYQKSFDVVPGTKQMRIEVKMGHSHPAGWKPEEIGRFIDSYCRGGDPLPVPATPQIDGDQVTLQYTSAVPLKAANLHYTTDSGPRSKRDWQTVPAKIDGQTITVPKPPADANTWFLSLTDTRDAMVTTAVQFED</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
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    <name>A0A518IQ17_9BACT</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
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    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
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                <person name="Mueller R.-W."/>
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                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
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                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <source>
            <dbReference type="EMBL" id="QDV55163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="75" mass="8713" checksum="F9A57E088B5EE225" modified="2019-10-16" version="1">MNLIVAETIRILPFFLADYPDVHSHLIDRQLCVRMIGSYVDVQSKFRREYLLEWGVLKAMLADDTSDEPTKMAEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQ45</accession>
    <name>A0A518IQ45_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_11850</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <location>
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            <end position="372"/>
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    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="403"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="461" mass="51121" checksum="7ACADB411C048AAA" modified="2019-10-16" version="1">MTSILHLFIFVFCAVAAGARARFIQHNLFSVLVFAGIGVIHGLVPLLRHTWLRFPETPEAFAAALYCAVGLPVFVMGWIWGQKACKQELQTSLVAGQIRDKSPLFKLVFWICVTAATTAFFLRLWVMGISISDALHGGRFEFRFSGGPIAAMVSYGCLLSMIPGFLGFLINRKYALFGVIFCIAFTTLVFVVSRGSRGLPLGILGSGLVGFLISRPRIKTLNLAIVSFVTIAILSLAISLYEIRKQLATSTATEIGQLLISGDAYADLLTRDPLNYHQMFVQVCKMVPTQADYTPLATQRRILFFFVPHSRFPELKPEDVNATIGHQVFMLPKNAVVTIPPTIPGDAYINFCGYPGIVYLLALGWAIGATISLSQRSYSLYLSATPCYLYYVMMGIRGQPYELFLEFVFLVASTNIVIWTLQRVFNAQLPPLKRPSLRRVRPSIARRQVACNFQASSGQQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQ75</accession>
    <name>A0A518IQ75_9BACT</name>
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        <recommendedName>
            <fullName evidence="1">PKD domain-containing protein</fullName>
        </recommendedName>
    </protein>
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        <name evidence="2" type="ORF">Mal33_12140</name>
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    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
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                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
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                <person name="Merkel B.J."/>
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                <person name="Labrenz M."/>
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                <person name="Overmann J."/>
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                <person name="Kaster A.-K."/>
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                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="component" value="Chromosome"/>
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    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="CalX-like_sf"/>
    </dbReference>
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        <property type="entry name" value="Dockerin_1_rpt"/>
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        <property type="entry name" value="PKD_dom"/>
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    <dbReference type="Pfam" id="PF00404">
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    </dbReference>
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    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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            <end position="511"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="826" mass="87164" checksum="6613FF7BFF6C0F9A" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQD5</accession>
    <name>A0A518IQD5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">Mal33_12330</name>
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    <organism evidence="2 3">
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    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
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                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
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                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
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                <person name="Galperin M.Y."/>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <location>
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            <end position="20"/>
        </location>
    </feature>
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        <location>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="138" mass="14918" checksum="5A51F922D7970882" modified="2019-10-16" version="1" precursor="true">MLRVLLLTIAMTVTASQAMAIGELKKEWSNIYAGDDSGDFKTVARKAGCNLCHVKGVKDKKTAESRNEYGTAMTAFLKSKDIKIGDLKAQYKDDSTKEAAVKTMTTMFETVNKEKSKDGEAFGAKISAGKLPATDANL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQK5</accession>
    <name>A0A518IQK5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
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                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021879617" evidence="1">
        <location>
            <begin position="21"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="187" mass="21282" checksum="416FCB03C708AB67" modified="2019-10-16" version="1" precursor="true">MKILLSAAVAVMALATTAQAQWVVPHTTTHHHNVPHTTTHTDYVQHGNHVDAVPHTTTHVDRVPHTTTHYDHVSPYGNQPIYNQPYRSSRPVIQGQYIQGQTYPQQGRVIYQNGIQQSGYVQPYHSYRPSYQSSGHLHTQTHTDYVPHTQTHIDYQRHGNHLHAVPHTTTHIDAVPHTTTNIHYGHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQL6</accession>
    <name>A0A518IQL6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_13500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021876776" evidence="1">
        <location>
            <begin position="30"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="180" mass="19729" checksum="CADB747AC504E0F7" modified="2019-10-16" version="1" precursor="true">MFRKLLTYLTMTTVVLHALLGCCMHHAHAGHTHCHDVAQVIVDVPHVVGFCDAGHNSDGHSHEAPKTSCQNQRVVDGSSSRDCLYGKASDAGPHQLCSVSDYTCSHGPHESCDKADCNIVADQRDNDFSLILSSDWSPILTDSLSLSSQNSLALRTVYSSPLDPHCVQLPLRIRTQVWRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQP3</accession>
    <name>A0A518IQP3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cobalt-zinc-cadmium resistance protein CzcC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">czcC_2</name>
        <name evidence="3" type="ORF">Mal33_13750</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021954833" evidence="2">
        <location>
            <begin position="26"/>
            <end position="507"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="507" mass="56054" checksum="7D73FD768C392716" modified="2019-10-16" version="1" precursor="true">MRSFLFKSGLSVIATAGMFCSTATAQMPSMGSTASPIGRTYTPPPPVPSAPYGLDQLDPSGPLFPGVRFDGSDFGSTPAPVYVDGEMISEAFPMETVVQGYQLDDFLTLAAQNNPTIRQAQLQISAQTAKALQAGLYPNPTLNYIGEQIGVDVEGDKDSPGEFQGMTVSQRFVTAGKLKLSREKYMRRAHISEHLAMAQQFRVCNDVRIHFFRALAAREIVELRKELLKTAEDGAVTARELYNQGQATRPQVRKSSIALQRARLDVLTAENHYRESFRRLVAIVGVDLTDGIVSGDLMPQGDPLSYQEAMSLVLTESPELAAARAKLAADRVTVRREQVEWVPDIVAEGGAGYNFEAKETTAAAGVSIELPVFDRNQGTILQAQLDYRRQQEEIRRTELMLGQQMANVYQQYLTALQIATEYDRVIIPEAELAYQEFLESYKANRVDWPTVLDAQMDYFDSRLTRVQQLEQVRTNEVLVRGYLLHGGLMAAPGPTPPGHIDAVAKPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQP5</accession>
    <name>A0A518IQP5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_13790</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="146" mass="16557" checksum="9DE93DDB0F3EA056" modified="2019-10-16" version="1">MGTRISDRFKFKQILLDVEDDGPYVFPPLPETEPPVWLDDYPPGTPDPGPRPPWWPDDAIWPPQPETPVVIEVPPSPHIWPRLPPDHPYHLPPGHSYPDSLPPGHPGGAYPAMPDYPVVHPSDWGEDWPSYPGILDDWPPTYEDNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQT2</accession>
    <name>A0A518IQT2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative major pilin subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_14260</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010710">
        <property type="entry name" value="DUF1289"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011453">
        <property type="entry name" value="DUF1559"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06945">
        <property type="entry name" value="DUF1289"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07596">
        <property type="entry name" value="SBP_bac_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="319" mass="35147" checksum="723CB8505C0D2709" modified="2019-10-16" version="1">MPSVKEPPIASPCTNRCRLDCQAICSGCGRTKDEITGWSAASPAEQLTIVRLAKLRQPKFQAAGFTLIELLVVIAIIGILVALLLPAVQAAREAARKMSCKNNLRQQGIALHNYHDVHQSLPTGCIEWRSWGAPPTQRQFAWSAMLLPFLEQQNVHAQIDWSLPYDSPENLPAASTRLSVYECPTATERPATRGRSDYGGIYGERIVDREPEDGLFLYERSVRFRDIRDGLTQTLAVAEDVGGPDSEWINGRNVFVQAYGINDPDAWIGDNEIRSLHTGGATVLFADGRTILMAETIDKQLLGKLITRGKGEVVDSSAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQU9</accession>
    <name>A0A518IQU9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Chromosome segregation protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_14380</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029605">
        <property type="entry name" value="FAM184"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18870">
        <property type="entry name" value="PTHR18870"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="776"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="850"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1057"/>
            <end position="1077"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="69"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="378"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="629"/>
            <end position="726"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1077" mass="122521" checksum="E680C96CF4AD2D53" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQV4</accession>
    <name>A0A518IQV4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transposase DDE domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_14460</name>
        <name evidence="5" type="ORF">Mal33_27690</name>
        <name evidence="6" type="ORF">Mal33_35490</name>
        <name evidence="7" type="ORF">Mal33_40070</name>
        <name evidence="8" type="ORF">Mal33_47260</name>
    </gene>
    <organism evidence="4 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 9">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002559">
        <property type="entry name" value="Transposase_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032806">
        <property type="entry name" value="YbfD_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01609">
        <property type="entry name" value="DDE_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13808">
        <property type="entry name" value="DDE_Tnp_1_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="domain" description="DDE_Tnp_1_assoc" evidence="3">
        <location>
            <begin position="23"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="DDE_Tnp_1" evidence="2">
        <location>
            <begin position="138"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV55472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV56770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV57539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV57991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV58702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="240" mass="26052" checksum="BA1D899F79B1A24E" modified="2019-10-16" version="1">MELYSTYGETTVKVPAAGSLLAILAAIPDYRGRKGRRHSLAAMLAAIICGLLTGAKGCTAIAQWLHDQEPEFWHSIGFTRKPPTSNCFRDVLLGLPPETLENAVRAWVTEYLAAVPGELRPVALDGKTLCGTLQPHGQSIHLLAMFDTATGGVIAQARMPGHTNEHKAAMRLLRSVVLKGRLVTGDAMFCQRDICREITDSGGDYLVAVKDNQPELKETIESEFRSGRSPLQRTRSATAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRH1</accession>
    <name>A0A518IRH1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Choline-sulfatase</fullName>
            <ecNumber evidence="11">3.1.6.6</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">betC_4</name>
        <name evidence="11" type="ORF">Mal33_16580</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="PTM">
        <text evidence="7">The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sulfatase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.6.6" evidence="11"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047753">
        <property type="term" value="F:choline-sulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004423">
        <property type="term" value="F:iduronate-2-sulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16030">
        <property type="entry name" value="iduronate-2-sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035874">
        <property type="entry name" value="IDS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024607">
        <property type="entry name" value="Sulfatase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00523">
        <property type="entry name" value="SULFATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0106">Calcium</keyword>
    <keyword evidence="5 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022004634" evidence="9">
        <location>
            <begin position="23"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase" evidence="10">
        <location>
            <begin position="28"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="157"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="471"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="modified residue" description="3-oxoalanine (Cys)" evidence="7">
        <location>
            <position position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR600917-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QDV55679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="510" mass="55565" checksum="00100934079EB62D" modified="2019-10-16" version="1" precursor="true">MVRIQTSFALAIGTCLLSAAIAAGGDRPNVLLICVDDLKPTIGCFGDPVAVTPNIDALASRGVRFDAAYCNQAVCSPSRNSLMTGLRPQTIGVYDLGTHFRLAVPDAVTFSQYFKQLGYRAEGLGKIYHTGHGNINDEASWSVPLWRPRAAQYVLPESLQNHRPDSKGRNRGPATEAADVSDETYADGKIAREAIARLTAASKRQDQPFFIAVGFLKPHLPFVAPQKYWDLYQPDALPMPEVVVPPTGAPSYAAVKGGELRSYSDMHDKKEIDPQTTRHLIHGYYAATSYADAQIGCVIDKATQLGLLDNTIVVLWGDHGWHLGDHGMWCKHTNYEQAARIPLIVAAPKSQPGLVSNSLVETVDIYPTVAELAGLPQPKGLDGISFANLIEKPDAATRDHVTHVYPRGSRLGRAIRDPRYRLVQWKSPGGKDATAELELYDYQTDPLETKNVASENPEVIARMLDLLAQQPEAKRQWKAKGKPGSNSNGKGSKKATGKPKPVNTDEKTGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRM8</accession>
    <name>A0A518IRM8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_17130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010732">
        <property type="entry name" value="T6SS_TssG-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35564">
        <property type="entry name" value="PTHR35564"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06996">
        <property type="entry name" value="T6SS_TssG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03347">
        <property type="entry name" value="VI_chp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="204"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="234"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="419" mass="46352" checksum="D16D495531C8CD52" modified="2019-10-16" version="1">MIDSVSHSTSIAGDASFTTGIAADAPHPLERLPVGSVGHELFRKPSKFDFFEAVLLLQQLAASEVDQPAAPIGKFAQPSQESLRFTVPHSQAFPTASIESIRWDAQQQRPQVCINFMGLTGPSGTLPRSYTQRLQQIEATSRHTDRHALRDWLDNFNHRMVSLFFDAWAKYRFPVAIRRQQFEPAKRKPSPTIVRVALSAIAGLSPPEPETKPHQAERNAHAAAASSQPKPSDEAKADQNESPRGEGTIDRDELLGLAGLLSQRPMNVANLQSALKQALGVPVRVKQFDSCWLNLETESQSRLGVEKCKLGYDTMLGERIWSRQQKVQIEVGPLSARDFQRFLPPSENHLGDGFRRLGEMVRVCVGPSLDFDIRPLLKIEQPLETQLTAETSLTRLGIDSWIGTPDDTAVANDAIFPGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRP5</accession>
    <name>A0A518IRP5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_17390</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="666" mass="73404" checksum="809AE5FFAE004AB3" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRT4</accession>
    <name>A0A518IRT4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cytochrome oxidase maturation protein cbb3-type</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_17870</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004714">
        <property type="entry name" value="Cyt_oxidase_maturation_cbb3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41532">
        <property type="entry name" value="PTHR41532"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03597">
        <property type="entry name" value="FixS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00847">
        <property type="entry name" value="ccoS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="70" mass="7403" checksum="C12665AB8279B30C" modified="2019-10-16" version="1">MSVLFVALPLALALGAAGMIACVYCIRGGQYDDLETPAVRILIDDRDTRPQPAKAAESDLDRRGSADPDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IS45</accession>
    <name>A0A518IS45_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Penicillin-binding protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">pbpE</name>
        <name evidence="3" type="ORF">Mal33_18940</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021871284" evidence="1">
        <location>
            <begin position="24"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-lactamase" evidence="2">
        <location>
            <begin position="37"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="375" mass="41041" checksum="0708A76A4A01A005" modified="2019-10-16" version="1" precursor="true">MKMLAHCSLMILLSLTTNLAVRAADSGDSRFDAIEPIVRRGIEAGQLPGAVVAVADSTKILYLRAFGDRQIEPTREALTTDTIFDLASLTKPVATATSVMLLVQRGEVDLDQPVAKYLPEFAVEGKEAITVRDLMLHVGGMIPDNSIRDYQKGIDVAWERLFALKPRSERGEKFAYSDVGFLILGKLVERVSGTTLDQFTQKEIFQPMGMETTSYQPDPALRDRIAATEPRDGELLRGKVHDPRAALLDGVAGHAGLFSTAEDLVRYGQMILSVDDETTSAPRVLDQKTIAAMIQPHRVPRGTRTPGWDHQSPYSSNRGTTFSDSAVGHGGFTGTVLWIDPEKDRVFVFLSSRLYPDGKGSVNRLAGEIATIIGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISI3</accession>
    <name>A0A518ISI3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UPF0229 protein Mal33_20270</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_20270</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0229 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01232">
        <property type="entry name" value="UPF0229"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006698">
        <property type="entry name" value="UPF0229"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30510">
        <property type="entry name" value="PTHR30510"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04285">
        <property type="entry name" value="DUF444"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="57"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="57"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="431" mass="49478" checksum="B75F1F22BE197307" modified="2019-10-16" version="1">MHVVDRRQNPKAKSLGNRQRFLRRVKSHMRKAFAESIRQRKIADLEGGQEVSISSKDLHEPTFHHDPKVGHRDYVLPGNHDYRPGDEIEKPSGGSGSGSGGSADGDGEDSFVFALTREEFLDLFFEDLELPNLAKRKLKSMASPSWVRAGYSTDGSPQRLNKRETMRRSLARRIALGRPKLAEVEALQAELQQAQTAGDTDEIARLRKLIDAQQTRMRAVPYLETVDLRYSRIQRVPKPTTQAVMFCLMDTSASMTEQLKDMAKRFYMLLHLFLKRHYKAVELVFIRHTYTAQEVDEQTFFHGRETGGTVVSSALEEMLKIVKQRYPVEDWNIYAAQASDGHNFDHDMPQTLRLLEQEILPICQYYAYIEVNDDQWPGDSVLWHGYFPLVDRHDNFAQAEVATASEIFPVFRDLFDSRQRSGSSTKPRVDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISN9</accession>
    <name>A0A518ISN9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Denitrification regulatory protein NirQ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">nirQ_1</name>
        <name evidence="3" type="ORF">Mal33_20830</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011704">
        <property type="entry name" value="ATPase_dyneun-rel_AAA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07728">
        <property type="entry name" value="AAA_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_5" evidence="2">
        <location>
            <begin position="57"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="306"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="325" mass="36094" checksum="304E330C5A16F8A8" modified="2019-10-16" version="1">MNAEAAKGFVEVDGVRLKLSVPHQSKTQWIGQGEILTQLLACWLTVDPTDLPLTPRLVGPPGVGKTQLAIAGAQHRELPIYIYQCTADTRPEDLLVTPVLAQDGKISYHASPLVTAMLCGGVCILDEGNRMNEKSWASLAPLFDQRRYVESIVAGITIGAHENFRAAVTMNQDESTFEIPDYILSRLQPTLEVGFPDPQDEMAILQYHLPFAEAEMLALTVDFLQRSHQLKLDFSPRDGINMLRYALKRLSQDGAHPLSRDQAWHEALQNCLGPDALDLDSLAERKQRTLGGNSVPMGLADFFFDPNDPLHPDRDDEVDEEDLDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITC3</accession>
    <name>A0A518ITC3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Protease 3</fullName>
            <ecNumber evidence="5">3.4.24.55</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ptrA_2</name>
        <name evidence="5" type="ORF">Mal33_23240</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the peptidase M16 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.55" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001431">
        <property type="entry name" value="Pept_M16_Zn_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="SSF63411"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00143">
        <property type="entry name" value="INSULINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M16" evidence="3">
        <location>
            <begin position="17"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M16_C" evidence="4">
        <location>
            <begin position="169"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV56342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="412" mass="45979" checksum="1BCA85C979528BB8" modified="2019-10-16" version="1">MTLEFKQHTLANGLQIIAEINPAGYTAAFGFFVRSGARDEQPEELGLSHFLEHMVFKGTARRTAADVNRELDELGGQANAYTSEEQTVYYTTVLPKYQDRAIDLLCDIMRPALRDDDFQTERQVILEEIAKYDDQPPFGAFERSMELYFGGHPLGGRVLGTPESIGEMTSTAMRKYFERRYDPQNMLLSVAGCVDFDAVVRQVEALAGDWPSADLPPRIAAPTVGGEAKVELEVPDSSQTYVIRVGAAPAISSDDRFAMRMLVSMMGEEGGSRLFWDLIDTGRADVATMWTQEFQDTGLLFTYLSCAPDDVESNLALVDGAIEVFVKNGPTSEEIQQTQNRMCAGLILSSERPSNRMFSIGNAWQMRGVYETLDDQLKRYRGVGEADLQRVLAEYPMRFTTEVRTVTKTPAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITD2</accession>
    <name>A0A518ITD2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Bacterial membrane flanked domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_23310</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005182">
        <property type="entry name" value="DUF304"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03703">
        <property type="entry name" value="bPH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="56"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="84"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="bPH_2" evidence="3">
        <location>
            <begin position="111"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="203"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV56349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="239" mass="26739" checksum="59836CE3283C94BE" modified="2019-10-16" version="1">MTAPAPRSAQWLYRGVWKILVDCFRVPDHPPTLPVVDGGFYRSFQPSRRFLSYLKFNFWVIAAVIDLVIAVALAAVAIEEEKLAMLLAVLAIPLILVGHLVAYIALHLRYDTMWYVITDRSLRARRGIWVIYEHTITFENVQNVYLRRGPLQHLFGISELVVETAGSSQGEAESPFASGNKLLVQGIEDAAELREQIMSRVSQSRSAGLGDDQTTSPTSGFSPRHVAMLCEIRDEIKGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITH2</accession>
    <name>A0A518ITH2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_23750</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="324" mass="36355" checksum="62B994EF21DD9DEF" modified="2019-10-16" version="1">MMHFRIWITLILAAQGSIMLGQEIPLTPECVVRFATVAEGAEVLEAEDTFTQRLSRFDLQSRLNTREEVNSTDYRRSAAEDIQPWTDAFIATVRPAVEQLAARVGDWNLPLPEEILLVCTKGNSEAGAPHTRGNAIVLPEKRIVRRPEDMLRLLAHELFHIASRQSPQWRDQLYATIGFEPCDEVQLPAADQNRRITNPDAPIVQHYITVDVDGQSVDVAPVLFSSVAEFDPSHEKSFFAYLQVKFVQLEKQDGTWTPVLRDDGSFVGHAMGDLDGFMSQVGRNTKYLIHPEEILADNFSYLVTGKKVASPEVLTQIEALLVSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITJ9</accession>
    <name>A0A518ITJ9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_24020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="57" mass="6335" checksum="3C53D6B3629BD77E" modified="2019-10-16" version="1">MGVPFCSFLADKLGGAVKPREWFLVPLPVISEAVQRITDGSISDYYYDPESASLELR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITK6</accession>
    <name>A0A518ITK6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Sulfoacetaldehyde dehydrogenase</fullName>
            <ecNumber evidence="5">1.2.1.73</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">safD</name>
        <name evidence="5" type="ORF">Mal33_24120</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.73" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102984">
        <property type="term" value="F:sulfoacetaldehyde dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="4">
        <location>
            <begin position="19"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV56422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="479" mass="51877" checksum="D59DEE20B0ECFF68" modified="2019-10-16" version="1">MLANSYPYYLANEPVAANQDLVVTDKYTGEAATKVALADSAAIDRAIAASVQAAEPMRRMPPYERQNVLNHCVARFTERSEELAMSLCIEAGKPIKDSRGEVSRLIDTFRIAAEESVRIGGEVMNLEISPRARGYRGLYKRVPIGPCSFISPFNFPLNLAAHKVAPAIAAGCPFVLKPASRTPIGALIIGEVLAETDLPKGAFSILPCRRDGADLFTTDDRLKLLSFTGSPAVGWDLKARAGKKKVVLELGGNAACIVDADSDLNDVTQRLVFGAFYQSGQSCIGVQRILAHDSIYNELRDRLVAATIKLVAGDPKEESTFIGPMISEQEAARLESWITTAVQAGGKLLCGGKRDGAMLDATLLEDVPQDQAVCTQEAFGPVAVMSRFNNFQEALNEVNDSVFGLQAGIFTRDIYKIQQAWDELDVGGVVIGDVPSWRVDNMPYGGVKDSGLGREGVRFAMEDMMELRNLVIRTPGNTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITT7</accession>
    <name>A0A518ITT7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phage terminase, small subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_24930</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006448">
        <property type="entry name" value="Phage_term_ssu_P27"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05119">
        <property type="entry name" value="Terminase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01558">
        <property type="entry name" value="sm_term_P27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="167" mass="18491" checksum="3EA9DCAD6F0EEBD7" modified="2019-10-16" version="1">MPKKKATTKPRPGTKRGRPKGATTKQPANTASEKALAAVPKPPAYLGKYAKEYWVTVGPVLIEAKLLTNSHLGAFAALCEAWHEYRTNQDWITANPDKLTFATETGYVAEDPRIRFRNKALDTLQKLWSKFGMTPKALADLGKLTDTKSSIPAIAIFARSKYDDLEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITU8</accession>
    <name>A0A518ITU8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_25020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd08054">
        <property type="entry name" value="gp6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021146">
        <property type="entry name" value="Phafe_gp6_head-tail"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011738">
        <property type="entry name" value="Phage_CHP"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02215">
        <property type="entry name" value="phage_chp_gp8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="190" mass="21201" checksum="84FABB43F8ACD11F" modified="2019-10-16" version="1">MQYELTTLQSPAMQPLTLAAAKLHLYEDEEHNDDDITRAIADATLWLERQTDLRLITQKTRLTADNFPAAGTPITLPVWPVRSIDAITYVAADGTETTLATESVSLRKNDYGRSRIAMKDWAPWPATRHTPDAVTIDVEVGFADADSVPEIYLRPLLTLIAFFYENRGDSDIAFPQVLGDLISNLRPADE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITW7</accession>
    <name>A0A518ITW7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phage integrase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_25190</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
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                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
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                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
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                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 4">Mal33</strain>
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            <end position="370"/>
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        <source>
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    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
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        <submittedName>
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        </submittedName>
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
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                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <end position="32"/>
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            <dbReference type="EMBL" id="QDV56576.1"/>
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        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="667" mass="73024" checksum="2F92BE8E91213B73" modified="2019-10-16" version="1"> </sequence>
</entry>
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    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
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                <person name="Bruemmer F."/>
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                <person name="Spormann A.M."/>
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                <person name="Jetten M.S.M."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="11 12">Mal33</strain>
        </source>
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        <reaction evidence="1">
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        </reaction>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HATPase_C"/>
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        <property type="entry name" value="His_kinase_dom"/>
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        <property type="entry name" value="HisK_dim/P"/>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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    <keyword evidence="5 11" id="KW-0418">Kinase</keyword>
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    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HAMP" evidence="10">
        <location>
            <begin position="349"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="8">
        <location>
            <begin position="423"/>
            <end position="644"/>
        </location>
    </feature>
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        <location>
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            <end position="784"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="9">
        <location>
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            <end position="931"/>
        </location>
    </feature>
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        <location>
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            <end position="416"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="6">
        <location>
            <position position="717"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="6">
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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        <source>
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        <source>
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    </evidence>
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        <source>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="QDV56655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="936" mass="103341" checksum="82DCCA396AF724C4" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IU86</accession>
    <name>A0A518IU86_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytochrome c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Mal33_26420</name>
    </gene>
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        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetes</taxon>
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        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
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                <person name="Storesund J.E."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8 9">Mal33</strain>
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</entry>
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            <dbReference type="EMBL" id="QDV56713.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
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            <dbReference type="Proteomes" id="UP000316770"/>
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    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
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    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
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                <person name="Jeske O."/>
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                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
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                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
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            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016627">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001104">
        <property type="entry name" value="3-oxo-5_a-steroid_4-DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010721">
        <property type="entry name" value="DUF1295"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32251">
        <property type="entry name" value="PTHR32251"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06966">
        <property type="entry name" value="DUF1295"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50244">
        <property type="entry name" value="S5A_REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="30"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="93"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="130"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="186"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="S5A_REDUCTASE" evidence="6">
        <location>
            <begin position="136"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV56735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="255" mass="28647" checksum="8EFDD74808FC0F01" modified="2019-10-16" version="1">MLASAAAIACLMLAIWLLSLWKRDASIVDIGWGIGFMLVAWTAYWIADRDSADWLLPVLTTIWGVRLSGYLFWRNHGQPEDYRYREMRAKWGSAFAWISLLTVFGLQGVVMFVVALPIQIGTALVDRDLAWLKVVGAIVWAAGLCFESMGDWQLARFKADPGNKGIVLDSGLWRYTRHPNYFGDFLVWWGLFLVSLSLTAAWWTIIAPLLMSVLLMRVSGVTLLETKLSTSKPGYAEYVARTNAFFPGPVKTGRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUG7</accession>
    <name>A0A518IUG7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AhpC-TSA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_27270</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016209">
        <property type="term" value="F:antioxidant activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="9"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="AhpC-TSA" evidence="2">
        <location>
            <begin position="148"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="313" mass="34218" checksum="8920E8794F019B5A" modified="2019-10-16" version="1">MRYALRGAAVYHLAWGALAIMMPATMLGWLGADGDGLALTLWQYIGLLVGLFGIGCGIASRNPTGHWLLLTIGLMGKIFTATGFALAFSTGAVPMAIGWTVLTNDLIWMVPLALILWESAHTAHAVDSAHSEPEADDPMNDLRTNTGKSLNELANAHPQMIVFLRHAGCTFCRQTLADISLQRALIEATGCRLLFVHLGPEDAQATEVFRRYDVDDVPRISDPKCRLYRQFGLELGGFSQLFGLRVWLRGLIYGFVNGHGIGAIQGNSFQMPGVYLYHCGMILDGIRHELASDRTNYVDFARQIEQSPPAVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUR8</accession>
    <name>A0A518IUR8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Altronate dehydratase</fullName>
            <ecNumber evidence="4">4.2.1.7</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">uxaA</name>
        <name evidence="4" type="ORF">Mal33_28340</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UxaA family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.7" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008789">
        <property type="term" value="F:altronate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd11613">
        <property type="entry name" value="SAF_AH_GD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007392">
        <property type="entry name" value="Gal/Altron_deHydtase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013974">
        <property type="entry name" value="SAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044144">
        <property type="entry name" value="UxaA/GarD_SAF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04295">
        <property type="entry name" value="GD_AH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08666">
        <property type="entry name" value="SAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00858">
        <property type="entry name" value="SAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAF" evidence="3">
        <location>
            <begin position="13"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV56833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="518" mass="54595" checksum="7AAA68BA43BC22E2" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUT4</accession>
    <name>A0A518IUT4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase</fullName>
            <ecNumber evidence="2">2.7.6.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">folK</name>
        <name evidence="10" type="ORF">Mal33_28490</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 7,8-dihydroneopterin triphosphate: step 4/4.</text>
    </comment>
    <dbReference type="EC" id="2.7.6.3" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00077">
        <property type="reaction ID" value="UER00155"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003848">
        <property type="term" value="F:2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046656">
        <property type="term" value="P:folic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00483">
        <property type="entry name" value="HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.560">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000550">
        <property type="entry name" value="Hppk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035907">
        <property type="entry name" value="Hppk_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01288">
        <property type="entry name" value="HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55083">
        <property type="entry name" value="SSF55083"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="folK"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0289">Folate biosynthesis</keyword>
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    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HPPK" evidence="9">
        <location>
            <begin position="6"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="206"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="208"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV56848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="320" mass="34944" checksum="670E244551B0534E" modified="2019-10-16" version="1">MPHCLISLGSNLGDRDELMRSAALAIARHPDVLAMRCSRIFTTPPVGGPSGQSIFFNAAAVIETTLSTAGVLNLLQQTEQDLGRVRKQRWDQRSIDLDVVLYGDFVGASLQLKLPHPRYTARGFVLAPAQDVAADWRDPRFGWTLRQLYEHLQAAAPSVALVGGGSELRSEICNQLSAQHGIAIRRRSASSPAMSIIGHAPGTVAATDQTPPAPQTANISTPDNTPWVADFVPEAIATTSPEIASRDPNMPRLIARLHRTTPETRWPSPQIIYRNGWNWPEYRLEVDDLPWAVSEVAAAIDSMQCEVHPITPDGNWASPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUW3</accession>
    <name>A0A518IUW3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytochrome c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Mal33_28870</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010496">
        <property type="entry name" value="3-keto-disaccharide_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036280">
        <property type="entry name" value="Multihaem_cyt_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037524">
        <property type="entry name" value="PA14/GLEYA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011658">
        <property type="entry name" value="PA14_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13442">
        <property type="entry name" value="Cytochrome_CBB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06439">
        <property type="entry name" value="DUF1080"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07691">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00758">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48695">
        <property type="entry name" value="SSF48695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51820">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022138386" evidence="5">
        <location>
            <begin position="20"/>
            <end position="1190"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="6">
        <location>
            <begin position="320"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="6">
        <location>
            <begin position="419"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="domain" description="PA14" evidence="7">
        <location>
            <begin position="506"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="6">
        <location>
            <begin position="664"/>
            <end position="850"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV56886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1190" mass="129094" checksum="3B72930CE50705DA" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IV13</accession>
    <name>A0A518IV13_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lipoate-protein ligase LplJ</fullName>
            <ecNumber evidence="3">6.3.1.20</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">lplJ</name>
        <name evidence="3" type="ORF">Mal33_29300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein lipoylation via exogenous pathway; protein N(6)-(lipoyl)lysine from lipoate: step 2/2.</text>
    </comment>
    <dbReference type="EC" id="6.3.1.20" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00537">
        <property type="reaction ID" value="UER00595"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016979">
        <property type="term" value="F:lipoate-protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009249">
        <property type="term" value="P:protein lipoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004143">
        <property type="entry name" value="BPL_LPL_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004562">
        <property type="entry name" value="LipoylTrfase_LipoateP_Ligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12561">
        <property type="entry name" value="PTHR12561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03099">
        <property type="entry name" value="BPL_LplA_LipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51733">
        <property type="entry name" value="BPL_LPL_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BPL/LPL catalytic" evidence="2">
        <location>
            <begin position="31"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="241" mass="27400" checksum="D819620B3E697798" modified="2019-10-16" version="1">MQLLDLSLPQSAGNLALDEALLEAAEAAGSQSDSEVLRLWKFDRPTVVVGRGSKVEDEVNREFCDSVSIPILRRCSGGTSVTVGPGCLLYSLVLNTDLRPELKDLDRAHQFVMQTICDAVARLLGRIEFQGTCDLTWQNRKFSGNSLRVARRHLLYHGTLLFDFPIDLVQQTLRVPPRQPDYREGRSHDQFVINLPLGELQLRDAMADAFEVQGNLQQWPQERVHQLVESRYSKSEWNFRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVB6</accession>
    <name>A0A518IVB6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATPase family associated with various cellular activities (AAA)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_30250</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011703">
        <property type="entry name" value="ATPase_AAA-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041628">
        <property type="entry name" value="ChlI/MoxR_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07726">
        <property type="entry name" value="AAA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17863">
        <property type="entry name" value="AAA_lid_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_3" evidence="1">
        <location>
            <begin position="47"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="AAA_lid_2" evidence="2">
        <location>
            <begin position="255"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="328" mass="36087" checksum="2A4F74D68DF4592D" modified="2019-10-16" version="1">MTAPQIDEQIAQYSQTCTKLIDEVGRVLVGQEAMVSRLLIGMLTGGHILLEGVPGLAKTLTVSSLAKAIHTGFSRIQFTPDMLPADVIGTEVFNPKEATYSIKQGPIFSNLILADEINRAPAKVQAALLEAMQERQVTIGTETFRFEDPFLVMATQNPIDQEGTYPLPEAQVDRFMLKVMVDYPTRDEERKVVDRMAGGKPMPEISAIATPEDIMGARGVVEKIWCDDKVRDYVVDVVRATRNPAELGVRGLEGMIETGASPRGSLNLMKASKAHAFLQGRNYITPHDVKSLAPDVLRHRVMLSYEAEAEGKTVDDCIRQILDNVPVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVG9</accession>
    <name>A0A518IVG9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator MprA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">mprA_3</name>
        <name evidence="3" type="ORF">Mal33_30780</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="18"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="141" mass="15543" checksum="D9CAEEC579428C57" modified="2019-10-16" version="1">MIDSTGGDSDPNPQTVPTILIADDDRELVAALSRRIMHLGFRVTIAHDAISALVLIKRDRPDMIVLDIHMPAGNGMCVLEMIRSEWTWSDIPVVIVSGGATPSMIQRVRDDNAHFVPKSTGMWPSLQRHITQTLTPFCIGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVN7</accession>
    <name>A0A518IVN7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribose-phosphate pyrophosphokinase</fullName>
            <shortName evidence="6">RPPK</shortName>
            <ecNumber evidence="6">2.7.6.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">5-phospho-D-ribosyl alpha-1-diphosphate</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Phosphoribosyl diphosphate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Phosphoribosyl pyrophosphate synthase</fullName>
            <shortName evidence="6">P-Rib-PP synthase</shortName>
            <shortName evidence="6">PRPP synthase</shortName>
            <shortName evidence="6">PRPPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 8" type="primary">prs</name>
        <name evidence="8" type="ORF">Mal33_31500</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>ATP + D-ribose 5-phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + AMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15609"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.7.6.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="6">Binds 2 Mg(2+) ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Metabolic intermediate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate from D-ribose 5-phosphate (route I): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.6.1" evidence="6"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00087">
        <property type="reaction ID" value="UER00172"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004749">
        <property type="term" value="F:ribose phosphate diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006015">
        <property type="term" value="P:5-phosphoribose 1-diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009165">
        <property type="term" value="P:nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009156">
        <property type="term" value="P:ribonucleoside monophosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00583_B">
        <property type="entry name" value="RibP_PPkinase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000842">
        <property type="entry name" value="PRib_PP_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029099">
        <property type="entry name" value="Pribosyltran_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005946">
        <property type="entry name" value="Rib-P_diPkinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037515">
        <property type="entry name" value="Rib-P_diPkinase_bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10210">
        <property type="entry name" value="PTHR10210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14572">
        <property type="entry name" value="Pribosyl_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13793">
        <property type="entry name" value="Pribosyltran_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01251">
        <property type="entry name" value="ribP_PPkin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00114">
        <property type="entry name" value="PRPP_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pribosyltran_N" evidence="7">
        <location>
            <begin position="27"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="217"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="60"/>
            <end position="62"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="119"/>
            <end position="120"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="153"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="219"/>
        </location>
        <ligand>
            <name>D-ribose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="244"/>
        </location>
        <ligand>
            <name>D-ribose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV57149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="340" mass="37222" checksum="9CA03FECA99B3AA6" modified="2019-10-16" version="1">MPATMLNFQVPTPSPTLQQRASKMRELKIFSGRANPELSHNVCNELHLSPGAITLGKFPDGENFCKIDEDVRGRDVYLVQPTCPPVNDTLMELLIMIDSCKRASAQRITAVIPYFGYARQDRKDEGRVPITAKMVANIITRAGADRVLTMDLHAAQIQGFFDVPVDHLYAAPVLNQHFLEQEYDPNELVVVSPDEGSIKRAVGHKERLGGHLAIVDKRRSSATEVEQHTIIGSSVEGKICLMFDDMISTAGSICGAASLVHASGAKEIHVAATHGIFSGPAIERIKASPIDSIVITDTIPLTPGKMLPNIKVRSVAKFLAEAIKRIHNDQSISAMFRNKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVZ6</accession>
    <name>A0A518IVZ6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">pknB_15</name>
        <name evidence="7" type="ORF">Mal33_32650</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="5">
        <location>
            <begin position="63"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="6">
        <location>
            <begin position="341"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="216"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV57261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="451" mass="50221" checksum="B51C3454C892C72E" modified="2019-10-16" version="1">MASWDRARLHDKRQARDTMNKLPDESDGRAEHVSTRPLSTSIGLEETGPGLTDDTPELDNPRYRIDEEIERGGMGAIFSARDLQLLRRVAIKVLRSDRIEIDSARQGFHDEARIMSFLSHPGVTPIYESGTCKDGRPYYVMKLIDGTTLADMLASQTFSTSHLLYIFADVCQTVAFAHSRGVVHLDLKPGNVMVGEFGEVHVMDWGLARFEAGPPEGSDWAGRTDAPKGTVNGTPGYMSPEQARGRKLGPGADVFSLGAILCEILIGHAPYEGKDLHQIHRRAMKGSMQKTLDVLDQSAQDCALVRLAKNCLARRVRDRPRSAVEVAQAMATYHESAFQRMESDMNRFFELSLDLFCIATADGYFQRINANFSRVLGHTDADLLARPFLDFVHPDDVAETVKQMQLLQQGQAVVGFRNRYRTASGDFKVLEWMAQSVDNDNIIFAVARSVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IW70</accession>
    <name>A0A518IW70_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_33460</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022051674" evidence="1">
        <location>
            <begin position="29"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="224" mass="23569" checksum="041CBAB9FFAEF940" modified="2019-10-16" version="1" precursor="true">MRNQIPTIAALLAVYVAPQFCLSKVAAADPVNRVEAVGLFEVAAIDLVPANADEPGKSLQSGGSAAAGTVDRDPIADRLASLMKPLGQIRLEPADDGTKAPENRAAAQLPAGETVITAEFGPLSPPNRYPICSCHNPLYFEEPDLERCGNGCGIATTAVSAVHFFANTLTLPYQIAADPPCTTQCAAGDCRCCEEMPRMRPFECKLHAATLQGLATAGFVFLLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWE3</accession>
    <name>A0A518IWE3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Polyphosphate kinase 2 (PPK2)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_34200</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008976">
        <property type="term" value="F:polyphosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016898">
        <property type="entry name" value="Polyphosphate_phosphotransfera"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022488">
        <property type="entry name" value="PPK2-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022486">
        <property type="entry name" value="PPK2_PA0141"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03976">
        <property type="entry name" value="PPK2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028756">
        <property type="entry name" value="PPK2_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03707">
        <property type="entry name" value="PPK2_P_aer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PPK2" evidence="4">
        <location>
            <begin position="50"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV57410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="304" mass="36188" checksum="E712A5431646D3AA" modified="2019-10-16" version="1">MSDQYTEQLNRLQEEFLDSIDEEIELELDDSRFEQLSARGEGEYDAKRLARTTYFRELLRLQRELVKLQDWVVKTNAKIVVIFEGRDAAGKGGAIKRITQRLNPRVCKVAALPAPSEREKTQWYFQRFISHLPAGGEILLFDRSWYNRAGVERVMGFCTDKEYEDFLQTAPVFEKMLVDSGIHLIKYWFSITDEQQEFRFNCRIHDPLKQWKLSPMDLESRRRWEQYTVAKERMLQATHRPESPWWIIEADDKKRARLNCIRHLLDQIDYAEVEQSTVELPSRQREPDYERNPIPSDMIVPAFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWZ6</accession>
    <name>A0A518IWZ6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA polymerase sigma factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rpoE_5</name>
        <name evidence="6" type="ORF">Mal33_36210</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
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        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000838">
        <property type="entry name" value="RNA_pol_sigma70_ECF_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01063">
        <property type="entry name" value="SIGMA70_ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="4">
        <location>
            <begin position="37"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="5">
        <location>
            <begin position="135"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="108"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV57608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="199" mass="22925" checksum="459D9906B2EAF481" modified="2019-10-16" version="1">MQSTMSSPTIESQSVPIRDLIDAAQRGDTDAYAQVMARYQDRLYNAMRNFVGCPILAEDIVQDAFVRAFVHLGSFRQESAFYTWLYRIALNARHTYAEKQRRLVPMESVPDGARPHGKRSVESPSAAIERNESCEQVQNAIKRLDDSFREVLVLREFEGYDYQKIAEILEIRVGTVRSRLSRARSQLRRELSAYEQSIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IX54</accession>
    <name>A0A518IX54_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_36850</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="142" mass="16106" checksum="D69ED9A3A5D3DE54" modified="2019-10-16" version="1">MLLLDSDHLSVLWYSDGAEFERLYSRLATHTAADVFVSIVTIDEQLRGWLAFVKKASRIDGVVKGYAMFQQVLERFVETQVVGFDDAEADVFTDLRSQKIRIGTMDLRIASIANANDLTLLTRNTVDFVRVPSLRFEDWTAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IX62</accession>
    <name>A0A518IX62_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Serine-aspartate repeat-containing protein F</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">sdrF</name>
        <name evidence="5" type="ORF">Mal33_36810</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001434">
        <property type="entry name" value="DUF11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033764">
        <property type="entry name" value="Sdr_B"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01345">
        <property type="entry name" value="DUF11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17210">
        <property type="entry name" value="SdrD_B"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="SdrD_B" evidence="4">
        <location>
            <begin position="487"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="domain" description="SdrD_B" evidence="4">
        <location>
            <begin position="606"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="domain" description="SdrD_B" evidence="4">
        <location>
            <begin position="851"/>
            <end position="929"/>
        </location>
    </feature>
    <feature type="domain" description="DUF11" evidence="3">
        <location>
            <begin position="971"/>
            <end position="1106"/>
        </location>
    </feature>
    <feature type="domain" description="SdrD_B" evidence="4">
        <location>
            <begin position="1147"/>
            <end position="1222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="9"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1088"/>
            <end position="1110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV57668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1660" mass="177112" checksum="407734C4A0F1D2C5" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IX82</accession>
    <name>A0A518IX82_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_37070</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007263">
        <property type="entry name" value="DCC1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04134">
        <property type="entry name" value="DCC1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="142" mass="16287" checksum="66759FD38AFA0469" modified="2019-10-16" version="1">MFKSPDLADPDSRPDADVVIFDGQCNFCRGGVERLNWLDRRNRLAFISLHDERVAERYPDLSHDDLMQEMFVVDGEGNRHGGSDAVRYLSRQLALLWPIMPVLHLPGSAGLWRWMYKQVAKRRYRLAGKNCDSGGCKIHLNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXG7</accession>
    <name>A0A518IXG7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_37820</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="248" mass="28464" checksum="CF824BDDDA92FC94" modified="2019-10-16" version="1">MPNPIPKQDAYELEVFSQFVSFADIPIATETIFKREPPEPDILCDHENCGQLGFELVQLVPQTYKHRLGLREIAQNAMQQSYEHMNERQKKQFSEKFRNATIHILLEPSATKGAVHRNTPQLLKELLDISISHEGELEELLSTKVRSTFDFVFVQISDTDSLKFSVGDFGHLDHAMLQSLKNKMCKTYSSGYPIDLLAYVEDASYFPQSIWKEALDSYLKELDNTGPFQRIWLADIPKRCVICTYPSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXL6</accession>
    <name>A0A518IXL6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Flagellar motor switch protein FliG</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">fliG_2</name>
        <name evidence="14" type="ORF">Mal33_38430</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Bacterial flagellum basal body</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the FliG family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009425">
        <property type="term" value="C:bacterial-type flagellum basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003774">
        <property type="term" value="F:cytoskeletal motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000090">
        <property type="entry name" value="Flg_Motor_Flig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023087">
        <property type="entry name" value="Flg_Motor_Flig_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011002">
        <property type="entry name" value="FliG_a-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032779">
        <property type="entry name" value="FliG_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028263">
        <property type="entry name" value="FliG_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30534">
        <property type="entry name" value="PTHR30534"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01706">
        <property type="entry name" value="FliG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14841">
        <property type="entry name" value="FliG_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14842">
        <property type="entry name" value="FliG_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00954">
        <property type="entry name" value="FLGMOTORFLIG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48029">
        <property type="entry name" value="SSF48029"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00207">
        <property type="entry name" value="fliG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="14" id="KW-0966">Cell projection</keyword>
    <keyword evidence="6" id="KW-0145">Chemotaxis</keyword>
    <keyword evidence="14" id="KW-0969">Cilium</keyword>
    <keyword evidence="7" id="KW-0283">Flagellar rotation</keyword>
    <keyword evidence="14" id="KW-0282">Flagellum</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021968929" description="Flagellar motor switch protein FliG" evidence="10">
        <location>
            <begin position="25"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="domain" description="FliG_N" evidence="13">
        <location>
            <begin position="9"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="FliG_M" evidence="12">
        <location>
            <begin position="116"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="FliG_C" evidence="11">
        <location>
            <begin position="218"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF14841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF14842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="QDV57828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="336" mass="36939" checksum="D9AC822729241AAA" modified="2019-10-16" version="1" precursor="true">MEKSKFETSLRRCAVLLMSLSTKAATIVMSRLTTAQVEAISLEIARMESVGGTEQEEVMHAFMGTKTSALNVSCGGLNLAKELIRQSMGTDADPVIQRIEQSIEQKPFAFVRRIEPRNLIQFVQDEHPQTIALILSHLPEGYCAEVLSGLDPEKQLEVIQRIAVVGSADTLAMADLERGLEMRLASLVNGTNLHVGGVEHVAGILNVSERSVERTIMEALAEEEPELVDEIRHLMFVFEDIAKMGDKDIQSLLKNVEASKWACALKGCSEPLVNKVMKNMSSRAADNLREEMGFLGAVRLSDVEAAQQGIVDMVRTLEDAGEIARPTGEEEEEFVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXL7</accession>
    <name>A0A518IXL7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">16S ribosomal RNA methyltransferase KsgA/Dim1 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_38480</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000179">
        <property type="term" value="F:rRNA (adenine-N6,N6-)-dimethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001737">
        <property type="entry name" value="KsgA/Erm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020596">
        <property type="entry name" value="rRNA_Ade_Mease_Trfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11727">
        <property type="entry name" value="PTHR11727"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01131">
        <property type="entry name" value="RRNA_A_DIMETH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_25" evidence="4">
        <location>
            <begin position="93"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV57833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="241" mass="26546" checksum="8C07F2A5FBE62F13" modified="2019-10-16" version="1">MVLPGTGRNAAAASAVAEEAMGSYHFGSSCEARPLDDSPPFFKQRTDLLGNNSLQFVKSFLRQPGAVGAIAPSSEQLAQTMVGWFDWESARGVVEYGPGTGVFTKHVVQKLHPDAKFFAIERDPELVAIVQQKLPEVDVVEESVANVVALCQARGIEQVDAIVCGLPWASFPDTLQRECIDAMMQVLRPGGQFATFAYWQGLLLPAGQRFKRRLGDYFSTVEYSPTVWRNLPPAFVYRCTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXM8</accession>
    <name>A0A518IXM8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Inositol 2-dehydrogenase</fullName>
            <ecNumber evidence="8">1.1.1.18</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">iolG_12</name>
        <name evidence="8" type="ORF">Mal33_38580</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.18" evidence="8"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016798">
        <property type="term" value="F:hydrolase activity, acting on glycosyl bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050112">
        <property type="term" value="F:inositol 2-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008152">
        <property type="term" value="P:metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019546">
        <property type="entry name" value="TAT_signal_bac_arc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01409">
        <property type="entry name" value="TAT_signal_seq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0520">NAD</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021846721" evidence="6">
        <location>
            <begin position="35"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="domain" description="GFO_IDH_MocA" evidence="7">
        <location>
            <begin position="40"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV57843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="434" mass="47609" checksum="12B4FF5C6C9030F1" modified="2019-10-16" version="1" precursor="true">MMQNDSTRRGFLKTSTIAATGAALTSSIARTAHAAGSDEIRFVVVGCGGRGTGAAMQIMNTKGNTKLVAVADAFGDKAERSIKSLANKHKDKVDVPKERIFTGLDAYKQAIDVDCDLVVIATPPGFKPQQFEYAVNKGRHIFMEKPVAVDAPGVRRVLKSVEESKKKNLMVGIGLQRRHEPQYIETIDRIHNGAIGDVIAQRVYWNGGGIWYRPKTEGQSEMAFQCNNWYHFNWVCGDQICEQHIHNLDVGCWVKGSYPVECNGMGGREMRMGGDATKSQIFDHTFCEYTFADGTKMFSQGRHLAGSWTHVGEAVHGSKGTADPSGSITGPNAWKFEGQRLNGHQQEQHDLIEALMAGEIYNEGEYGAKSTFTAILGREACYSGKVIKWDQLLAEGKDICPGIDEYTIDSVPPTVPGEDGKYPHPVPGKYNPFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXU0</accession>
    <name>A0A518IXU0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_39170</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="30"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="175" mass="18753" checksum="4CB04B83EA752210" modified="2019-10-16" version="1">MKAKAVRSRKTQIDRSTTPRKPLRRAGFSLFEIILALAIFGVAMAMLGNIVSNGAKAAIEARDLARAQIMCESKMAEVMLNTAGPQPISNVSLESNDTLRQWEYSVLTEPAPMSGMVAVQVKVQSVSQDASVVPVEFTLTRWIIDPAMDLQGLEDEAAALAAEEDAMVTSEGAGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXZ6</accession>
    <name>A0A518IXZ6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_39790</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="533" mass="59753" checksum="7F74209AC139D419" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IY29</accession>
    <name>A0A518IY29_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Heme/hemopexin-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">hxuA</name>
        <name evidence="2" type="ORF">Mal33_40160</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008638">
        <property type="entry name" value="Filamn_hemagglutn_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05860">
        <property type="entry name" value="Haemagg_act"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00912">
        <property type="entry name" value="Haemagg_act"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01901">
        <property type="entry name" value="adhes_NPXG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Haemagg_act" evidence="1">
        <location>
            <begin position="51"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1816" mass="187355" checksum="ABE638BD2211BD5B" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYC5</accession>
    <name>A0A518IYC5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative CtpA-like serine protease</fullName>
            <ecNumber evidence="7">3.4.21.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Mal33_41070</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the peptidase S41A family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.-" evidence="7"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07560">
        <property type="entry name" value="Peptidase_S41_CPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041489">
        <property type="entry name" value="PDZ_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004447">
        <property type="entry name" value="Peptidase_S41A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005151">
        <property type="entry name" value="Tail-specific_protease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17820">
        <property type="entry name" value="PDZ_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03572">
        <property type="entry name" value="Peptidase_S41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00245">
        <property type="entry name" value="TSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00225">
        <property type="entry name" value="prc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 7" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0720">Serine protease</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0802">TPR repeat</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022049934" evidence="5">
        <location>
            <begin position="28"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="39"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="6">
        <location>
            <begin position="239"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV58090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="552" mass="60840" checksum="3A895634F3A2ABBB" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYG9</accession>
    <name>A0A518IYG9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Inner membrane protein YbhN</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ybhN</name>
        <name evidence="7" type="ORF">Mal33_41490</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022791">
        <property type="entry name" value="L-PG_synthase/AglD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03706">
        <property type="entry name" value="LPG_synthase_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="15"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="45"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="105"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="139"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="180"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="221"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="299"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV58132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="330" mass="34980" checksum="4A2F03A38A7F3F3B" modified="2019-10-16" version="1">MNNNEPSLVGRLKKIAGPVFGLILFSVAASFLYKKTQEITWDEFAAGVANIPLAYHLLACLLVALNYFVLTGNDVLAVQFVGAGSSGAEEGRPRLSYRKVGLVSFLAYAFSNNIGAVAAGIPIRVRFYSGWGLGTAQIVALLAFTSLSFWVGVCMVGGVVLSIAEIPMPPKIDLPVSSRILGFTLLAAIALYAALCTWWRRPLPLAGLKLLPPGPALMRKQIVVASMDLILVATTLYVLLPSGISASYLQVVGVYLLALAAAMLTQVPGGLGVLEAILLTLLASSDEAVILGALLIFRIYYYVVPLLVASVVLATVEVRSTRAARKLLSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYH4</accession>
    <name>A0A518IYH4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glyco_hydro_42 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_41620</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009341">
        <property type="term" value="C:beta-galactosidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004565">
        <property type="term" value="F:beta-galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013529">
        <property type="entry name" value="Glyco_hydro_42_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02449">
        <property type="entry name" value="Glyco_hydro_42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022170677" description="Glyco_hydro_42 domain-containing protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_42" evidence="2">
        <location>
            <begin position="59"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="372" mass="41587" checksum="734ADBC3DE968578" modified="2019-10-16" version="1" precursor="true">MRFAFGLGLILLTTISSASGETRSSRDEKKIAKPYGVFSSKVTPKSATHPLCKGLLLRTSWSKLEPQQGRYDFSDIDRQIEMTTRGNRNAESLAFSLAISAGLGGSAQGPNYPAWLIDEGVETMPIQFRGKEGLVPKMWDPRFQKRLKELADAVSQKFANDNRLQLVYVPQATANGVEGHFNGTSYAALTRSGLTADVWVGAVKQAAMAFADAFDTCAIAVEVHEVLGSPEIPMRILTELNRDPRYGDQIGAGMWWISGGTRYQPALVRALKNYPGDIYGQIIGNSSQPYRFGDKSGDFTTVYRQAIDLEVRYLEAWNFEFDFNTQNQNIENFNKYAHEKYAMGIANPRTPSFVKPKVTTQGFRRLRQRPQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYL0</accession>
    <name>A0A518IYL0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">TM2 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Mal33_41890</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="TM2"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
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    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="37"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="77"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="101"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="TM2" evidence="6">
        <location>
            <begin position="8"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="domain" description="TM2" evidence="6">
        <location>
            <begin position="76"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF05154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV58172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="143" mass="16453" checksum="C120C41192DAA22A" modified="2019-10-16" version="1">MNTYQPQTHSTTIGYICWIFGFFGAHRFYFGRPISGTIWAFTLGFFFIGWIIDLFLIPSMSRTANLRYNSGPFDFNVAWILLTFLGVFGIHRFYMGKWLTGLLWLCTGGLFMLGYLYDMWTLNAQVSECNFEAYAGQSAMSMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYQ4</accession>
    <name>A0A518IYQ4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cadmium, cobalt and zinc/H(+)-K(+) antiporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">czcD_2</name>
        <name evidence="7" type="ORF">Mal33_42420</name>
    </gene>
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        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1510.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002524">
        <property type="entry name" value="Cation_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027469">
        <property type="entry name" value="Cation_efflux_TMD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01545">
        <property type="entry name" value="Cation_efflux"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161111">
        <property type="entry name" value="SSF161111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01297">
        <property type="entry name" value="CDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
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            <end position="114"/>
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        </location>
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            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
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            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
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            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV58225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="310" mass="33266" checksum="2A51E7F3972BF19A" modified="2019-10-16" version="1">MSNRELAAWHEDHSFGQDQKKPGESRTIVVIAITVAMMVIEIVAGRLYESMALLADGLHMASHAAALTISVFAYIYARRYAHDACYSFGTGKVNALGGFAGALLLGIFSLMMVWESVHRILDPAEISFNQAILVAAIGLVVNAICATVLGHTHDHGDGSSCSHGHDHNLKAAYMHVLADALTSVLAIVALLAGKFWGWAILDPIIGIVGAIVVAKWSVGLLRSTSDVLLDRQATDLVLDRIRDAIEDDDHDVVDLHVWSIGPGLYATEIIIVSSNPVSPGDFKKMLPDDLSIAHAAVEVHQREDVPASAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYV9</accession>
    <name>A0A518IYV9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Biopolymer transport protein ExbB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">exbB_4</name>
        <name evidence="9" type="ORF">Mal33_42940</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the exbB/tolQ family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002898">
        <property type="entry name" value="MotA_ExbB_proton_chnl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01618">
        <property type="entry name" value="MotA_ExbB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
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            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="137"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="180"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="domain" description="MotA_ExbB" evidence="8">
        <location>
            <begin position="115"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV58276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="244" mass="25895" checksum="D46CF61365A4B332" modified="2019-10-16" version="1">MLNSSLAMAGLLAQTVDADAGGGSFWQILFSGGIVGLLIILLLFSLSLIAAFLIFDQFMALRRAEVIPEGVVEPIQKLLAERRVKEADAICRQKPSLLTFVMMSGLAEVDFGWPSVEKAMEEALAEQSARMMRRIEYLSVIGNIAPMVGLLGTVTGMIFAFQRVAISQGGAGAGDLAEGIYQALVTTVGGLIVAIPALGAFAVLRNRVDGLVAEVAYLAQHAMSGLKRRSVKRPVPGTPIPPVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYW3</accession>
    <name>A0A518IYW3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative efflux pump membrane fusion protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_42880</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <location>
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            <end position="183"/>
        </location>
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        <location>
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            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="235"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="263"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="296"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="365"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="393"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="434"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="domain" description="HlyD_D23" evidence="3">
        <location>
            <begin position="464"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="655"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="663"/>
            <end position="683"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV58270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="744" mass="81383" checksum="B0D1FE4C8B12C911" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYY9</accession>
    <name>A0A518IYY9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_43220</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021764895" evidence="1">
        <location>
            <begin position="28"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="436" mass="49217" checksum="B25A6E7FC30AD007" modified="2019-10-16" version="1" precursor="true">MTKVLRIIRSAALLSIGLFAVPSPANAQTDTYESPPIDYHKASVQDRITQLSAKIESGELQLQFDRQHGYLESVLEALDVPISSQTLVFSKTSLQRSRIAPRTPRALYFNDDVYVGWCVRGDVLEIAATDPQQGATFYTLEQTESKPPKFVRDRGQCLSCHASSRTQYVPGYLVRSVYPDSDGQPILGSGTFTTDQTSPLEERWGGWYVTGQHGTMRHMGNMLFSEAESREPELDRGANLQTLDTLLSTNRYLSPHSDIVALMVLEHQTQMHNAIAAANYETRQALHQSFQMNKFLEREEGHISESANRRIDASAERVLRYLLMRDEFELSDRVAGSSTFAKDFMDRGIKDSKGRSLRDLDLKQRLFQYPCSYLIYAPAFDGLPDQVRTRVLDKLAGILQGTVESPDDEHLTPEMRKQILEILRDTKPEFASRLAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ40</accession>
    <name>A0A518IZ40_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">D-ribose pyranase</fullName>
            <ecNumber evidence="2">5.4.99.62</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_43720</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>beta-D-ribopyranose = beta-D-ribofuranose</text>
            <dbReference type="Rhea" id="RHEA:25432"/>
            <dbReference type="ChEBI" id="CHEBI:27476"/>
            <dbReference type="ChEBI" id="CHEBI:47002"/>
            <dbReference type="EC" id="5.4.99.62"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="5.4.99.62" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0062193">
        <property type="term" value="F:D-ribose pyranase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048029">
        <property type="term" value="F:monosaccharide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005996">
        <property type="term" value="P:monosaccharide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1650.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023750">
        <property type="entry name" value="RbsD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007721">
        <property type="entry name" value="RbsD_FucU"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05025">
        <property type="entry name" value="RbsD_FucU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102546">
        <property type="entry name" value="SSF102546"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV58354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="149" mass="16353" checksum="68EECADC2B790BB9" modified="2019-10-16" version="1">MLKHELLHPKINEILARGGHYSKVLIADGNYPAYHTLGPSAELVSLNLAPGLVSCCQVLATLLTAIPIDAANTMMYPQSGPYALPADPPVWDEFRKLFADAKSDVQLEPIEQMQFYDAVRSPEHILTIQTGDQAIFANLLLTVGVRRAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZD2</accession>
    <name>A0A518IZD2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_44750</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="68" mass="7292" checksum="76B90FA928CDC776" modified="2019-10-16" version="1">MQFHPWQSVAIAPLLLCLCGCDGNVETTDDATRIEAEIPKLEIGDQPLDLQPSTDGDVDIDTPLPGDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZG8</accession>
    <name>A0A518IZG8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Carbamoyl-phosphate synthase large chain</fullName>
            <ecNumber evidence="13">6.3.5.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Carbamoyl-phosphate synthetase ammonia chain</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13 17" type="primary">carB</name>
        <name evidence="17" type="ORF">Mal33_45130</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>2 ATP + H2O + hydrogencarbonate + L-glutamine = 2 ADP + carbamoyl phosphate + 2 H(+) + L-glutamate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:18633"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="13">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="13">Binds 4 Mg(2+) or Mn(2+) ions per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="13">Amino-acid biosynthesis; L-arginine biosynthesis; carbamoyl phosphate from bicarbonate: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 13">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 1/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the CarB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.5" evidence="13"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00171"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00115"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004088">
        <property type="term" value="F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01424">
        <property type="entry name" value="MGS_CPS_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1030.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01210_A">
        <property type="entry name" value="CPSase_L_chain_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01210_B">
        <property type="entry name" value="CPSase_L_chain_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006275">
        <property type="entry name" value="CarbamoylP_synth_lsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005480">
        <property type="entry name" value="CarbamoylP_synth_lsu_oligo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036897">
        <property type="entry name" value="CarbamoylP_synth_lsu_oligo_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CbamoylP_synth_lsu-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005483">
        <property type="entry name" value="CbamoylP_synth_lsu_CPSase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011607">
        <property type="entry name" value="MGS-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036914">
        <property type="entry name" value="MGS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033937">
        <property type="entry name" value="MGS_CPS_CarB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02786">
        <property type="entry name" value="CPSase_L_D2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02787">
        <property type="entry name" value="CPSase_L_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02142">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00098">
        <property type="entry name" value="CPSASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01096">
        <property type="entry name" value="CPSase_L_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00851">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48108">
        <property type="entry name" value="SSF48108"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52335">
        <property type="entry name" value="SSF52335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01369">
        <property type="entry name" value="CPSaseII_lrg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00867">
        <property type="entry name" value="CPSASE_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51855">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="13" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="9 13 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 13 17" id="KW-0436">Ligase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="12" id="KW-0464">Manganese</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 13 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11 13" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 13" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ATP-grasp" evidence="15">
        <location>
            <begin position="133"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="15">
        <location>
            <begin position="683"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="domain" description="MGS-like" evidence="16">
        <location>
            <begin position="945"/>
            <end position="1081"/>
        </location>
    </feature>
    <feature type="region of interest" description="Carboxyphosphate synthetic domain" evidence="13">
        <location>
            <begin position="1"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Allosteric domain" evidence="13">
        <location>
            <begin position="945"/>
            <end position="1081"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="285"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="299"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="301"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="833"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="849"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="851"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>4</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="QDV58490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1081" mass="118389" checksum="FFB6A587A83C0852" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZM4</accession>
    <name>A0A518IZM4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">4-hydroxy-tetrahydrodipicolinate synthase</fullName>
            <ecNumber evidence="2">4.3.3.7</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">dapA_4</name>
        <name evidence="2" type="ORF">Mal33_45660</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DapA family.</text>
    </comment>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001365">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01130">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR001365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="306" mass="32555" checksum="B5C84571E861C556" modified="2019-10-16" version="1">MTSSASETLLRGVLPVLQTPFTEQGEFDFETLDREIQWAFDTGADGIVVAMVSEILRLSEQGRRELAEHVCKAAQGRGTSVVSVGAESTPVAVELAKHAESVGASAVMAIPPISTGLSSAATRDYFAAIAASISIPLVVQDASGYVGSAIDIGVYSKLLEQFGVDRILFKPEASPLGPNLSRLRDATAGKAQIFEGSGGINLVDCYRRGIVGTMPGTDLLDAIVALWNALQAGDDDRIYQLSLPISGIVALQLSAGLDGFLAIEKHLLVRRGIFKNTVQRQPVGWTLDAETAAEVDRLFDRLQDVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZV5</accession>
    <name>A0A518IZV5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Planctomycete cytochrome C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Mal33_46480</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011429">
        <property type="entry name" value="Cyt_c_Planctomycete-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011478">
        <property type="entry name" value="DUF1585"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013039">
        <property type="entry name" value="DUF1588"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013042">
        <property type="entry name" value="DUF1592"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07635">
        <property type="entry name" value="PSCyt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07627">
        <property type="entry name" value="PSCyt3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07624">
        <property type="entry name" value="PSD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07631">
        <property type="entry name" value="PSD4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022023256" evidence="2">
        <location>
            <begin position="24"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="domain" description="PSCyt1" evidence="6">
        <location>
            <begin position="43"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="PSD4" evidence="5">
        <location>
            <begin position="397"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="domain" description="PSCyt3" evidence="4">
        <location>
            <begin position="598"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="domain" description="PSD2" evidence="3">
        <location>
            <begin position="716"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="534"/>
            <end position="554"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV58624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="797" mass="89743" checksum="43FB55769010FA4F" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZX2</accession>
    <name>A0A518IZX2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">Methionine aminopeptidase</fullName>
            <shortName evidence="2">MAP</shortName>
            <shortName evidence="2">MetAP</shortName>
            <ecNumber evidence="2 3">3.4.11.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Peptidase M</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2 5" type="primary">map</name>
        <name evidence="5" type="ORF">Mal33_46650</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 2">Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 3">
            <text>Release of N-terminal amino acids, preferentially methionine, from peptides and arylamides.</text>
            <dbReference type="EC" id="3.4.11.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 3">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <cofactor evidence="2 3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <cofactor evidence="2 3">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="2 3">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="2 3">Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.18" evidence="2 3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046914">
        <property type="term" value="F:transition metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070084">
        <property type="term" value="P:protein initiator methionine removal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01086">
        <property type="entry name" value="MetAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01974">
        <property type="entry name" value="MetAP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001714">
        <property type="entry name" value="Pept_M24_MAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002467">
        <property type="entry name" value="Pept_M24A_MAP1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00599">
        <property type="entry name" value="MAPEPTIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="SSF55920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00500">
        <property type="entry name" value="met_pdase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00680">
        <property type="entry name" value="MAP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 5" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 3" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M24" evidence="4">
        <location>
            <begin position="17"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="110"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="207"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV58641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="265" mass="29090" checksum="E6F1D10921E6ADB5" modified="2019-10-16" version="1">MLQNRKKLLLQNAGREAMIAAGRFNAKLLDYVRPHVKAGIQTGAIDELIHKFTIDHGHKPATLGYQGFTKSCCTSVNEVICHGIPGEYTLVDGDIVNVDITSVVNGWFGDQSETFLIGDVSEEARAVTQCAFDCLYIGIDALTPGCKVSVIGEAIVAEAHSRGFSVVREYVGHGLGRQFHQDPSIPHYPNRQSRQDRLLPGMAFTVEPMINAGSRFTSLDNNDGWTVRTKDGRYSAQFEHTVLMTESGPQILTLTQDGPQKGHTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J008</accession>
    <name>A0A518J008_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_46940</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011446">
        <property type="entry name" value="BBP7"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07585">
        <property type="entry name" value="BBP7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022123476" evidence="1">
        <location>
            <begin position="30"/>
            <end position="579"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="579" mass="61758" checksum="27FF517D7A687336" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J071</accession>
    <name>A0A518J071_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Sodium Bile acid symporter family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_47660</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015103">
        <property type="term" value="F:inorganic anion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004706">
        <property type="entry name" value="Arsenical-R_Acr3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002657">
        <property type="entry name" value="BilAc:Na_symport/Acr3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43057">
        <property type="entry name" value="PTHR43057"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01758">
        <property type="entry name" value="SBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00832">
        <property type="entry name" value="acr3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="25"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="64"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="106"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="173"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="207"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="235"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="276"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="307"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="368"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV58741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="421" mass="44686" checksum="6051FB5262454FB4" modified="2019-10-16" version="1">MDETSSCPGNDAPNSGGGIGFFERYLTVWVGLCIVAGIVLGKVAPGLAKSLDAMAIYSGDAPVVSIPIAICLFFMMFPIMVKIDFGEVVRAGKAIRPVGLTLLINWAIKPFTMYAIASFFLGTVFLGLIGPDAVDYVKAPLGADVEVGATYGAGEVVIVDGVKMLQVPLWRSYLAGCILLGIAPCTAMVLVWGYLAKGNDGHTLIMVAINSLTMLVLYGLLGGFLLGVGQLPVPWKALLLSIAIYVALPLVSGYFTRKWLFTTKGEAWFRDRFLRYLTPVTTTALLATLVLLFSFKGETIVANPLTILWIAIPLTLQTVLIFALGYGISKGLGFNYETAAPTAMIGASNHFEVAIATATMLYGLSSGAALATVVGVLIEVPLMLALVKFCLKTKGWFAGGTGNEMNEAIAMQPQTSLEGEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0B5</accession>
    <name>A0A518J0B5_9BACT</name>
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        <submittedName>
            <fullName evidence="2">Helix-turn-helix domain protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">Mal33_48040</name>
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        <name type="scientific">Rosistilla oblonga</name>
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            <taxon>Planctomycetes</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1240.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003759">
        <property type="entry name" value="Cbl-bd_cap"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006158">
        <property type="entry name" value="Cobalamin-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036724">
        <property type="entry name" value="Cobalamin-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041657">
        <property type="entry name" value="HTH_17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036594">
        <property type="entry name" value="Meth_synthase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02607">
        <property type="entry name" value="B12-binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12728">
        <property type="entry name" value="HTH_17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52242">
        <property type="entry name" value="SSF52242"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51332">
        <property type="entry name" value="B12_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="B12-binding" evidence="1">
        <location>
            <begin position="157"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="282" mass="31504" checksum="45A9A8C8575736C5" modified="2019-10-16" version="1">MRVSESSVKRWCDRGLIPTIKTVGGHRRISVESLAQFLRDTKRTLTDPDKLGGYDEPVVALQPAPVVSDVSDEVGTFTTALLNGDEATCRQIIHQAYRRNNSFIDVAAQVVCSSMRLVGEMWESGRTDVLQERYGCEICFRLVNELAQYIQLPSSDAPLAIGCAPPGDQYQLPTHLVELVLRETGWNARSLGNNMPLKTMLDVVHQYKPRMVWVSISTIEDRGVFVDAFNDFAKQLPKEVVLVAGGRAMDDDLRPRLNYTAHCDNFYQLAGLASAMLTRREA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0G0</accession>
    <name>A0A518J0G0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_48430</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="181" mass="19652" checksum="68799743BC87B45A" modified="2019-10-16" version="1">MRRFAFLAVFTISQTLVCSYGYAEKVEAFGGAIKMETPEAWKSVQPRSRIVEKEYSISKEGVEGSARLTMMAAGGDIKANIDRWIGQFTAADGGSAKGSAKQEKLDVAGNEVHLIELQGTFKESMGGGPFAPGKTVKREDYEMLGAIVVNDGRKFFIKMTGPKAIVEDQKAAFKAMLKGIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0N6</accession>
    <name>A0A518J0N6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_49320</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="76" mass="8398" checksum="91566A1D3FE20DB5" modified="2019-10-16" version="1">MPSESRYAGDTLRGNLKLGLVSIVSILFSIRSVAPAGDHKREPGAAVRGRTPLRGARILKSHRRDRNADSQLFDRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0S8</accession>
    <name>A0A518J0S8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_49590</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012545">
        <property type="entry name" value="DUF1697"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36439">
        <property type="entry name" value="PTHR36439"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08002">
        <property type="entry name" value="DUF1697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF008502">
        <property type="entry name" value="UCP008502"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="179" mass="19595" checksum="43FC059522AB7209" modified="2019-10-16" version="1">MNTWIALFRGINVGGNNILPMAKLKSDLESLQLKNVRTYIQSGNVVFDSTARTAAPLAAKIARTIEQRHGFRPQLLLIKPDELRQAIASNPFPEAISDPKSLHFLFLAAPPAAPDIKSLENAESTSERYQITDSVFFLHAPDGIGRSKLAANAEKHLGVVATARNYRTVEKLSTMVSDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0V3</accession>
    <name>A0A518J0V3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acrylyl-CoA reductase AcuI</fullName>
            <ecNumber evidence="2">1.3.1.84</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">acuI_2</name>
        <name evidence="2" type="ORF">Mal33_49960</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.3.1.84" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043957">
        <property type="term" value="F:acryloyl-CoA reductase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014188">
        <property type="entry name" value="Acrylyl-CoA_reductase_AcuI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43677:SF1">
        <property type="entry name" value="PTHR43677:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02823">
        <property type="entry name" value="oxido_YhdH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKS_ER" evidence="1">
        <location>
            <begin position="11"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="330" mass="34657" checksum="53DAF07AC5602B56" modified="2019-10-16" version="1">MPFNALIVEKTDDSNVSVAMQSLTIDQLPAGNVTVAIQYTTVNYKDGLCMQPNNGFVRNYPLIPGIDFAGTVESSDDSRYKPGDKVVLTGWRVGESHWGGYSQKARVNADWLVPLPDGMTTRQAMAIGTAGFAAILAVLALEDHGLTPDQGEVLVTGAAGGVGSIATAVLGKLGYQVAAVTGRPETADYLKSLGAARIIPRGEIDTVSKKPLESETWAGCVDAVGGEMLARVLGQLKYGASVAAVGLAGGAAMPASVIPFLLRGVNLLGIDSVMQPYEKRLIGWQRLATDLPLDKLDTMIQPAKLADVPQLASDILKGQVKGRVVVDVNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J104</accession>
    <name>A0A518J104_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_50440</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="110" mass="12313" checksum="CF5ABCDA28ACBDDC" modified="2019-10-16" version="1">MRLSLPNSIRSLPLIASCVFILVAVGVGHYLMQDQTARMWHHPDPNKRSVKDWADRWYAGSAKCKVVAGCDCCAGVYEVRGSRLAILLFPRVIDDGIDWKSDGWVLPGRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J162</accession>
    <name>A0A518J162_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Laminin G domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_51010</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 33 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006558">
        <property type="entry name" value="LamG-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011040">
        <property type="entry name" value="Sialidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036278">
        <property type="entry name" value="Sialidase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13088">
        <property type="entry name" value="BNR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00560">
        <property type="entry name" value="LamGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50939">
        <property type="entry name" value="SSF50939"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022041058" evidence="3">
        <location>
            <begin position="22"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="domain" description="LamGL" evidence="4">
        <location>
            <begin position="63"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV59076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="582" mass="63648" checksum="4BB4CB796B66DA2A" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1D3</accession>
    <name>A0A518J1D3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative oxidoreductase</fullName>
            <ecNumber evidence="2">1.-.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_51790</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EC" id="1.-.-.-" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="248" mass="25691" checksum="F7502BF7F33729B4" modified="2019-10-16" version="1">MTFDVTNKTVLVTGANRGIGKAILEEALHRGAAKVYAAVRNVESAASLVAEHGDKVVPIRIDLDDPSSITAAADTATDADLVINNAGVLKTSSAVAADAIESLQFEMNANVYGLIRVAQAFAPVLKANGGGAFVQLNSVASVKTFADFATYCASKAASYSITQGLRETLREQGTQVVSVHPGPIDTDMGAAAGFDDAASPSSVATEIFNALAEGRFHGWPDPVAQQIGGAYQSFSENVIEADMQESPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1F1</accession>
    <name>A0A518J1F1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Aconitate hydratase</fullName>
            <shortName evidence="8">Aconitase</shortName>
            <ecNumber evidence="8">4.2.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">acn</name>
        <name evidence="11" type="ORF">Mal33_51990</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 8">
            <text>citrate = D-threo-isocitrate</text>
            <dbReference type="Rhea" id="RHEA:10336"/>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
            <dbReference type="ChEBI" id="CHEBI:16947"/>
            <dbReference type="EC" id="4.2.1.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <text evidence="8">Binds 1 [4Fe-4S] cluster per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate metabolism; tricarboxylic acid cycle; isocitrate from oxaloacetate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the aconitase/IPM isomerase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.3" evidence="8"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00223">
        <property type="reaction ID" value="UER00718"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003994">
        <property type="term" value="F:aconitate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047780">
        <property type="term" value="F:citrate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01580">
        <property type="entry name" value="AcnA_IRP_Swivel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.19.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.499.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044137">
        <property type="entry name" value="AcnA_IRP_Swivel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015931">
        <property type="entry name" value="Acnase/IPM_dHydase_lsu_aba_1/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001030">
        <property type="entry name" value="Acoase/IPM_deHydtase_lsu_aba"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015928">
        <property type="entry name" value="Aconitase/3IPM_dehydase_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006249">
        <property type="entry name" value="Aconitase/IRP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018136">
        <property type="entry name" value="Aconitase_4Fe-4S_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036008">
        <property type="entry name" value="Aconitase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000573">
        <property type="entry name" value="AconitaseA/IPMdHydase_ssu_swvl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11670">
        <property type="entry name" value="PTHR11670"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00330">
        <property type="entry name" value="Aconitase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00694">
        <property type="entry name" value="Aconitase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00415">
        <property type="entry name" value="ACONITASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53732">
        <property type="entry name" value="SSF53732"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01341">
        <property type="entry name" value="aconitase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00450">
        <property type="entry name" value="ACONITASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01244">
        <property type="entry name" value="ACONITASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="5 8" id="KW-0408">Iron</keyword>
    <keyword evidence="6 8" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8 11" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aconitase" evidence="9">
        <location>
            <begin position="70"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="domain" description="Aconitase_C" evidence="10">
        <location>
            <begin position="699"/>
            <end position="825"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QDV59171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="901" mass="97066" checksum="6D992551F59F0BB5" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1L9</accession>
    <name>A0A518J1L9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">VWFA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_52620</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13519">
        <property type="entry name" value="VWA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="2">
        <location>
            <begin position="96"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV59234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="310" mass="33619" checksum="5696A0294579EA2E" modified="2019-10-16" version="1">MMGLLHNFHFVRPLGLALIPIAIAVWWYWQRQLDPLRGWRQQIDPDLLEALVDDRDAKRDPMRYAMVAAWIVAAIAIAGPTWKLEPNPFAEDAPPLMIVLKAGESMLQTNPSPSRMERAQLKITDLAKARKGDPLGLLAYSGSAHLVLPPTQDTAVIGEMAAEISPDVMPVPGDRLDLAIAAAGGLLRERGSGGSLLVVADTADIDPSEVAKAHRSVGSPPIDFLALTEPDSAEAQTLRDVAAAIGGSVESLSIEDDDIQKILRFAQRRAAAGVSGESNRWQEAGYWLTPLLALFVAVSFRRQKSSQPKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1M4</accession>
    <name>A0A518J1M4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glutamine cyclotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_52530</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016603">
        <property type="term" value="F:glutaminyl-peptide cyclotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017186">
        <property type="term" value="P:peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007788">
        <property type="entry name" value="QCT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011044">
        <property type="entry name" value="Quino_amine_DH_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31270">
        <property type="entry name" value="PTHR31270"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05096">
        <property type="entry name" value="Glu_cyclase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50969">
        <property type="entry name" value="SSF50969"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="281" mass="31870" checksum="332EDC3B8A8210BD" modified="2019-10-16" version="1">MTDSNTSIETKPAAPTIGWSGYRWLLTAAVGLLTLGCVAMLLSANQSTTTPIATFEVVNVYPHDPAAFTQGLAIDGGRMYEGTGQYGSSSLRRVELASGKVLQSISLNRDLFGEGITVWKDSIIQLTWKKRRAFVFDRDTFQHRKTLRYAGEGWGLTHDGTHLIMSDGSSRLRFLDPETFREVRQITVHDGRRRIDDLNELEFVEGEIFANVWYNDSIARISPQDGRILGWIDLHNLWPARQRPTREHVLNGIAYDREAKRLYVTGKNWPKLYEVRIVDAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J225</accession>
    <name>A0A518J225_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="17">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Mal33_54240</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
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                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
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                <person name="Mueller R.-W."/>
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</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
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            <begin position="105"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV59452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="931" mass="98822" checksum="1675D88F4EA17DE9" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IM44</accession>
    <name>A0A518IM44_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_01150</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="85" mass="9517" checksum="24647714A0CF05DC" modified="2019-10-16" version="1">MPWLRHSMLSLRAIPGTRVPGLRMPWLRHSMLSLPVIPGTCVSGAMLTRRHDQLVLQRVGLFVAAGGPQHWDQLFAVLRIDAVQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IME5</accession>
    <name>A0A518IME5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CRISPR-associated protein (Cas_GSU0053)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_01930</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013403">
        <property type="entry name" value="CRISPR-assoc_prot_GSU0053"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09617">
        <property type="entry name" value="Cas_GSU0053"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02570">
        <property type="entry name" value="cas7_GSU0053"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="228"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="231"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="431" mass="46275" checksum="EB2968EADEE5AB49" modified="2019-10-16" version="1">MSFDYSKLKDAVKTGAALRCRTKLQPAGGEGDKVFPPTYAGAVYAMEYRRVPGRDQPVRCVLMDSVQSQANRFEEALQDAVDDERIKIPVVEVDFGEIPIVEPGSDDAGLYEPIGRVTSLQAPHRVADAILRDSELDGVAFRATTLGKKLSQATLRNATPLLELCPTALIFGIWDSTGPKGGLGVKFQRALVSEIIGIDAELGVKTSSRIDPLAIQLKSGPVYEGKNGDWTLDESQARMDKKKPKLKGKEGKPSEVNHGNIAPSLSETGRDPIGDSDRRVYLAGGVTIAYAEQTTVLSFPALRRLRFPLDGSSKTDAGSNLVAQTALAALGVCSAALAAERGLDLRSRCLLWPTEKPAWELLAQPGEAADQFMISADEAVALLEESIAKAVEAKLPWNTEPLVLKPAQKLVDLVRKSQELAVTSGAEDGGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMP7</accession>
    <name>A0A518IMP7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_03130</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="33"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="70" mass="7989" checksum="FFEA22630E267326" modified="2019-10-16" version="1">MSKPKEHKHNSDHQHTSHHNAAKSKKIHHDWRFWTAIVLMGLAMAAYVLSFDESLRPGDVDQAEVPMSAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMX6</accession>
    <name>A0A518IMX6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">D-threo-aldose 1-dehydrogenase</fullName>
            <ecNumber evidence="2">1.1.1.122</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">fdh</name>
        <name evidence="2" type="ORF">Mal33_03930</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.1.122" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047834">
        <property type="term" value="F:D-threo-aldose 1-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42686">
        <property type="entry name" value="PTHR42686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="1">
        <location>
            <begin position="68"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="388" mass="42461" checksum="127D9BE3E943FE36" modified="2019-10-16" version="1">MMTRRNLLQAGAALGMGAVVGGTASAQALKVQNSTGEFMKTKGNIDRDAALPMNETGNGKRYRPSSRMGLGGLAAGNGFNTISSDEEILQMLNAAWDSGVRYFDTAPFYGLSLSERRFGDLLRNKNRDDYVLSSKVGRLLTPSAEPLPKRWHWANHSPFHYRYDYSAAGTRRSVEDTLHRIGVSSLDIVFIHDLSPQNSDFGDDWLKYFDEAANGAMPELTKMREEGMIKAWGLGINTSHAVSKTLDVADPDIFLLALQYSILDHQEALDKTFPLLDERDISVVVGAPLNGGFLAGRDRFNYSSFIPEEVKTKFAAINDVAGKYGIDIKTAALQFAEAPSTVSAIIPGARTAQQVNENIASMKVEIPEAFWSELKTKNLIAQNAPTGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IN38</accession>
    <name>A0A518IN38_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase DDE domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_04520</name>
        <name evidence="3" type="ORF">Mal33_08390</name>
        <name evidence="4" type="ORF">Mal33_47640</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
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        <property type="entry name" value="Transposase_11"/>
    </dbReference>
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        <property type="entry name" value="DDE_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV58739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="459" mass="53450" checksum="0B2A8056D9C38A16" modified="2019-10-16" version="1">MAIMEDSLPAIKSFLPNTQVSAHFRSMLLRFLIAILTRHGRNSCMSAASAIEGKPRHRAQPGRFLKRYRQAIADLLTAITLKMLRDQDWNGRYLLLLDSTLVATAGQTVENTFSTGNSKRRPAKNRRYTKYKYQRKSCHCFVFALLLTPDGLRVPMWLPYYTKPYAKTRKIKHRTQAQLAAQLICDTQVPAGTELIVLGDTAFDAKCVRAACRERGYFWIVPVNTNRVFSAKKQGKRPRVSLRIEQLPASRFQTIRLSIGSGPCAAQRRASCHRTARRRDGTKSTRTYHVHSERSEVHNVGMVMLVFSSSKPIGKKIQREGTKLLMTNAKHLSARQVCELYSLRWQIELFFKELKSTLGMNQYSFKDFEAVESWMGIVLITFCYLEWTRRRKLADRRIDDRQRKCWKHARSYTVREALLLGIRYREHQWHLRRLKTSHGLRTLRKRYTELLSQEYRCLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IN55</accession>
    <name>A0A518IN55_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pup deamidase/depupylase</fullName>
            <ecNumber evidence="2">3.4.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">dop_1</name>
        <name evidence="2" type="ORF">Mal33_04730</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.4.-.-" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="P:modification-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010498">
        <property type="term" value="P:proteasomal protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004347">
        <property type="entry name" value="Pup_ligase/deamidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42307">
        <property type="entry name" value="PTHR42307"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03136">
        <property type="entry name" value="Pup_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="175"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="216"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="577" mass="63749" checksum="C0E65FCA2BCCEB5C" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INF1</accession>
    <name>A0A518INF1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Arylsulfatase</fullName>
            <ecNumber evidence="5">3.1.6.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">atsA_4</name>
        <name evidence="5" type="ORF">Mal33_05730</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="PTM">
        <text evidence="1">The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.</text>
    </comment>
    <dbReference type="EC" id="3.1.6.1" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004065">
        <property type="term" value="F:arylsulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
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        <location>
            <begin position="34"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase" evidence="4">
        <location>
            <begin position="38"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="224"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="modified residue" description="3-oxoalanine (Cys)" evidence="1">
        <location>
            <position position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR600917-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV54618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="575" mass="63534" checksum="F0D796732A3750FE" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INI7</accession>
    <name>A0A518INI7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_06180</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011453">
        <property type="entry name" value="DUF1559"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07596">
        <property type="entry name" value="SBP_bac_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="329" mass="35598" checksum="61BE2B34C0005BAF" modified="2019-10-16" version="1">MCRCKFRNAFSIIELLVVIGVAAIALAVALPAAQHTRAKARRIQCALRLSELSIATNIHLSTYNTFPYTSKNFGVFVNGSAKRFPAISPHSQLLASLDQAAFEKVAIFDPSLSWTDRQPISTVESNRILIKTSMPMFLCPSDSGPVGGNNYRANLGPDIGVFRGSPPTTHNGIGAFENGRALSPSSFSDGLSNTIMYSEKVIGDRNRTVYQAFRDNFVFSPGFTNRDEAARTCRQFATSTPLSHDSFGGTTWLFGGYNHTWYNHVATPNSFIPDCCTGLSFGGGDGLYTARSLHHGGVNVGMADGSTNFISNSIDALVWLQQSTRSSGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INM0</accession>
    <name>A0A518INM0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Amidohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_06320</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04909">
        <property type="entry name" value="Amidohydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="1">
        <location>
            <begin position="47"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="328" mass="35819" checksum="9594F195833BCB9C" modified="2019-10-16" version="1">MKSNPPESSKAATLSRRGCLQSGAAALTGLCLGTSHATESDPPLEIIDCHTHFYDPSRPQGVPWPGPGPLYRTVLPKHLRELKQYRPVTGTVIVEASAWVEDNAWLLDLAADDPFVLGIVGRIDPDQPDFAKHLARFSANPLFRGIRISVGLLKKLLEANDLAALKALADRGLALDVNGGPETPAVIAKLARRLPSLTIVQNHIGNVPVTADRPPQGWIDGIRAAADHKNVYCKISGLVESAARHSKQPAPTDLEFYRPYLDVVWNAFGDSRVIYASNWPVSDRGATYEDLQRIAMQYAAEKGATATANFCSLNSKQAYRWVDRPRSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INM6</accession>
    <name>A0A518INM6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_06480</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0301 (AlgH) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003774">
        <property type="entry name" value="UPF0301"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30327">
        <property type="entry name" value="PTHR30327"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02622">
        <property type="entry name" value="DUF179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="183" mass="19871" checksum="746A03AE99D72833" modified="2019-10-16" version="1">MTQLLNGKFLLASPYLPDSNFQRTVVFMVKHDVDGALGLVLTRPSDLRLQQLLESTMGSSGVREDLVYLGGPVEGPLCALHEDANLADLDCEGGLFVTSEQESIILLANRPNARVRFFAGYSGWGAGQLESEMKSGGWLTCDATADEVFGDFEPLWESLVKRVGRSIIGEAVPFASNVDSQMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INQ4</accession>
    <name>A0A518INQ4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_06670</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="65" mass="7536" checksum="A9847E52B0E23F5B" modified="2019-10-16" version="1">MNRHRERADAMNDKFTPVGLQHLECPSKLVVCQTLIFGLMVVDEVTSPHNLCRERTRGLVHYPKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INT8</accession>
    <name>A0A518INT8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phage T7 F exclusion suppressor FxsA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_07000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007313">
        <property type="entry name" value="FxsA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35335">
        <property type="entry name" value="PTHR35335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04186">
        <property type="entry name" value="FxsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="27"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="76"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="131"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="156" mass="16915" checksum="5975D573F2219EBB" modified="2019-10-16" version="1">MFLKLLLAFTIIPLVELAMLIQLSKATSLLVTVGIVIFTGIVGSMLARWQGALAWQRFRQALAEGRMPAPEVQDGLLIFFAAGMLLTPGLLTDAMGFLLLIPQTRLLARHCLAARIGSRFQIQTFGFGENAQPTQSDPNTIDAAAASVRSDKRTDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INY8</accession>
    <name>A0A518INY8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_07370</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022031672" evidence="1">
        <location>
            <begin position="21"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="218" mass="22477" checksum="F312F6B64D6718A4" modified="2019-10-16" version="1" precursor="true">MKRRKLCTGLLVIAFSTHQAFGVVGSQLHQDDAPPLPDGEPAVLMEDQLEPNEPADLEGLAAAILQLQTDIENDDQPCDDLLSRLDELQTSLTSLVVPEPHQVQYEQLIVDSNAIRGQLPCAGEEIIISEEEILIEEEFVDGCCQPTLGGAPIGGSGCCGGGGGGGGFGGGGLAGLAGLAGLAAIGSGDSGSKNRGKPNGNVISKRYGYGYGYGSYGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP00</accession>
    <name>A0A518IP00_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Manganese transport system membrane protein MntB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">mntB_1</name>
        <name evidence="9" type="ORF">Mal33_07760</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the ABC-3 integral membrane protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046914">
        <property type="term" value="F:transition metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037294">
        <property type="entry name" value="ABC_BtuC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001626">
        <property type="entry name" value="ABC_TroCD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001367">
        <property type="entry name" value="Fe_dep_repressor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036421">
        <property type="entry name" value="Fe_dep_repressor_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022689">
        <property type="entry name" value="Iron_dep_repressor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30477">
        <property type="entry name" value="PTHR30477"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00950">
        <property type="entry name" value="ABC-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02742">
        <property type="entry name" value="Fe_dep_repr_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00529">
        <property type="entry name" value="HTH_DTXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47979">
        <property type="entry name" value="SSF47979"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81345">
        <property type="entry name" value="SSF81345"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="77"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="110"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="134"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="166"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="211"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="249"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="273"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="298"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="325"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="domain" description="Fe_dep_repr_C" evidence="8">
        <location>
            <begin position="434"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV54811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="506" mass="54925" checksum="CF047E26BA64CCB6" modified="2019-10-16" version="1">MSRQRFLQRMLRWSGGLAGRRIRFALLLLAACGLIASSTAAGEEPAAMRSLANRELGWPSTEQWRRVIFLQDHNTRVVVLGTTLLGLAAGTIGSFTLLRKRALMGDALSHATLPGIGLAFIVATQLGFDGKTLPVLLLGAAVTGMIGVAGIVFIRSLTRLSEDTALGVVLSVFFGAGVAVLGVIQQMESGHSAGLESFIYGKTASMLPSDAWLIGGTGFVSCLVCFALFKELKLLCFDDGFAGSEGYSVTLLDGILMLLVVVVTIVGLQAVGLILVIALLVTPAAAARFWTHQLTRMVLLASGLGAISGMLGSATSALFPQLPSGAMIVLVATALFLFSMMLGPARGLLPRWLRRWRLNSSIERQHLMRGIYELLESRGYQGPENGDPIPSVSVDDLLRLRSWTMRRLKHGIRKAEEAGLLVQLPNQQIKVNKSGYHEAARLTHEHRLWEMYLITHAEVAATQVDRSADAIEHVLEPEMIDRLERLLQQSQRSTRVVDSPHPLSHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP29</accession>
    <name>A0A518IP29_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NMT1/THI5 like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_07870</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011852">
        <property type="entry name" value="TRAP_TAXI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42941">
        <property type="entry name" value="PTHR42941"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16868">
        <property type="entry name" value="NMT1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02122">
        <property type="entry name" value="TRAP_TAXI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="338"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="358" mass="37379" checksum="B4659B1D429EB157" modified="2019-10-16" version="1">MALMLQISQHRALVASLVLSALMLGCKKSDSTGDGGATGGRQFLSMGTAPVGGAFPVVGGAIAEVLNEHKGTVDWKVQAKGTKGSQENIRRLQQAELELALSNAAISYFAARGEAGWDKVYDIRAIATLAPNVALFIARADSGIQSIADLKGKRVITGPAGAGFQQFVEPILAEHGVAWDEITSLNATQSGAVDQLGDGAADAAFLGGAVPTGSITQAASTFDVTYIPFDESARQKLIEKYAFFHPATIPGGTYKGLDNDFLGLNVGSMHLITAASQSDELIYEVTKSIWENRAEIASKHPAGKAINEKNVARNTGIEYHPGAIKFYEEVGVLEAAEKPAAEEAPAADAPAEAPAAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP77</accession>
    <name>A0A518IP77_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">pknD_2</name>
        <name evidence="8" type="ORF">Mal33_08430</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13176">
        <property type="entry name" value="TPR_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="479"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="158"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="584"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="126"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV54878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1167" mass="128826" checksum="CC169AEF5C187431" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPQ4</accession>
    <name>A0A518IPQ4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_10450</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="227" mass="25628" checksum="3BA3E831367CE09E" modified="2019-10-16" version="1">MSPSHPTDRTIQLARQSTRWSQADSAGGYTMRYITAMRNYLIDLWGDGEAADKSLVLLLGHLASKGFGESEKGRLRDYLLRSARGAATAQYRREPSEVVPPIDQMQVDDPAWLDNWRECLLARVWRALERFEHANPGNFEYSALRLATDHPDDTESMLAIRVGNKFETQVTPQRFRITLEAARLRFAQLIADEVTDTLESPTTEDVNAELAAIGLQHLVVPFLGRTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPX4</accession>
    <name>A0A518IPX4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">AAA-like domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_11070</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033186">
        <property type="entry name" value="HerA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05872">
        <property type="entry name" value="DUF853"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF853" evidence="3">
        <location>
            <begin position="275"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="475"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="660"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="726"/>
            <end position="764"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV55138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="808" mass="89675" checksum="0583209D05069E1F" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQ81</accession>
    <name>A0A518IQ81_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">D-inositol-3-phosphate glycosyltransferase</fullName>
            <ecNumber evidence="2">2.4.1.250</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">mshA_2</name>
        <name evidence="2" type="ORF">Mal33_11900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.4.1.250" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102710">
        <property type="term" value="F:D-inositol-3-phosphate glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="187"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="382" mass="42404" checksum="037664BD61E70D96" modified="2019-10-16" version="1">MKMLFVAPMPPPMTGNSLPVKVLKEELQADHDIDVINLNKRQHKAAGITSAGRMARIMSVLCQFCLSQRRYDVLYITVAESWLGNVRDIVMLMICRKRLSTVVLHMLGGAGMHDILAKGKGVRFLLNRYLMGRVGAIVVEGDTQRNTFAHVAARSKIHVIPNFAEDYLFCSDVEVNQAFDDTAMVRILFLSNMLYGKGHLELLEAYMSLPAETRANVTLDFAGKLVFETESFRKMIDEDSNVTFHGPVYGSAKRDIYLKSHVFCLPTYYPYEGQPFCILEAYATGCAVVTTDHSGIRNVFQEPGNGFEVTKKSVDDLAAKITHVVENRSGLRKIALNNLEVARAKYTKDAYVESMSSVLQAVAKSLQSEDSSSSRGAEQGGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQN6</accession>
    <name>A0A518IQN6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Helicase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_13830</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase C-terminal" evidence="2">
        <location>
            <begin position="831"/>
            <end position="1002"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1130" mass="125584" checksum="3D03421E4D14EE06" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQP9</accession>
    <name>A0A518IQP9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RNA recognition motif (RRM, RBD, or RNP domain)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_13950</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="SSF54928"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RRM" evidence="2">
        <location>
            <begin position="9"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="143" mass="14146" checksum="34D814F59E27EE25" modified="2019-10-16" version="1">MHGSFVLGRKLYCGNLSFGVSSSDLEQLFAQFGTVESAQVITDRDTGRSKGFGFVEMGSDAEAQAAITGLNEQEHDGRSLTVNEARPREDRGGGGGGGYRGGGGGGRSGGGGGYGGGGGRSGGGGGYGGGGGGGRGGRRDDRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQS0</accession>
    <name>A0A518IQS0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Pyridoxine/pyridoxamine 5'-phosphate oxidase</fullName>
            <ecNumber evidence="5">1.4.3.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">PNP/PMP oxidase</fullName>
            <shortName evidence="5">PNPOx</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Pyridoxal 5'-phosphate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 10" type="primary">pdxH</name>
        <name evidence="10" type="ORF">Mal33_14070</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>H2O + O2 + pyridoxamine 5'-phosphate = H2O2 + NH4(+) + pyridoxal 5'-phosphate</text>
            <dbReference type="Rhea" id="RHEA:15817"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:58451"/>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
            <dbReference type="EC" id="1.4.3.5"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>O2 + pyridoxine 5'-phosphate = H2O2 + pyridoxal 5'-phosphate</text>
            <dbReference type="Rhea" id="RHEA:15149"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:58589"/>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
            <dbReference type="EC" id="1.4.3.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5 7">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
        <text evidence="5 7">Binds 1 FMN per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Cofactor metabolism; pyridoxal 5'-phosphate salvage; pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Cofactor metabolism; pyridoxal 5'-phosphate salvage; pyridoxal 5'-phosphate from pyridoxine 5'-phosphate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the pyridoxamine 5'-phosphate oxidase family.</text>
    </comment>
    <dbReference type="EC" id="1.4.3.5" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA01068">
        <property type="reaction ID" value="UER00304"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004733">
        <property type="term" value="F:pyridoxamine-phosphate oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008615">
        <property type="term" value="P:pyridoxine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01629">
        <property type="entry name" value="PdxH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000659">
        <property type="entry name" value="Pyridox_Oxase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019740">
        <property type="entry name" value="Pyridox_Oxase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011576">
        <property type="entry name" value="Pyridox_Oxase_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019576">
        <property type="entry name" value="Pyridoxamine_oxidase_dimer_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10851">
        <property type="entry name" value="PTHR10851"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10590">
        <property type="entry name" value="PNP_phzG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01243">
        <property type="entry name" value="Putative_PNPOx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000190">
        <property type="entry name" value="Pyd_amn-ph_oxd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00558">
        <property type="entry name" value="pdxH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01064">
        <property type="entry name" value="PYRIDOX_OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3 5 7" id="KW-0288">FMN</keyword>
    <keyword evidence="4 5 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-0664">Pyridoxine biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Putative_PNPOx" evidence="8">
        <location>
            <begin position="37"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="PNP_phzG_C" evidence="9">
        <location>
            <begin position="171"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="7"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5 6">
        <location>
            <begin position="190"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5 7">
        <location>
            <begin position="60"/>
            <end position="65"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 6">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 7">
        <location>
            <begin position="75"/>
            <end position="76"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 7">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 7">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 7">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 6">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 6">
        <location>
            <position position="126"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 6">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 7">
        <location>
            <begin position="139"/>
            <end position="140"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 7">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 7">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007301"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000190-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000190-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF10590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV55434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="212" mass="24132" checksum="657EAAA65E16D7FB" modified="2019-10-16" version="1">MDLSELRQEYAGQPLDVDSVDPNPFQQFTAWFDQASTAELLEPNAMVLATVDADGRPSQRTVLLKYFDESGFVFFTNYGSRKAQQIAANSHVSLLFQWLPLHRQVEVDGVATKVSSAESLKYFLKRPRESQLGAWVSRQSEVVSHRQLLEAKLEEMKTRFGKGEIPLPSFWGGFRIAPTRLEFWQGGPGRLHDRIEFRSDGRGGWNRSRLSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQS9</accession>
    <name>A0A518IQS9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_13930</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021302">
        <property type="entry name" value="DUF2780_VcgC/VcgE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11075">
        <property type="entry name" value="DUF2780"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="142" mass="14690" checksum="104A89C29F41F30A" modified="2019-10-16" version="1">MDELLQQLTDRLGIDPSTAQGVAGKAMAMIKENVDEATFKRLASSIPGLESIIMASETHDSGEAGGGLLGKLAGMASGMLGGSAGNALEMGAALSEKGLPTDKLGEFVTMLIEFIKSKAGDDVLEQVFAKFPMLKSLLDSQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IR24</accession>
    <name>A0A518IR24_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Bifunctional RNase H/acid phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_15230</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="SSF53254"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="218" mass="24368" checksum="F437F281F6695706" modified="2019-10-16" version="1">MQLYLIRHAQSANNSKPEAERVEDPEITELGHQQAAAIAKSIADQNVDFLVTSGFLRTLQTTQYLADSLRMPIHVWRDLHEVGGCYRGYIPGEEQGAPGMNRDAILAKYPGTTVDESIGTEGWWGCRSYETEAQATLRSEQMLARFAEQFGATDKVVVAVIHADFKVCMLRQILGNDFTRRHIGPMLNTGLTKFTVSEDAWRLNILNSITHLSSDQIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IR29</accession>
    <name>A0A518IR29_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Glycosyl hydrolases family 2, sugar binding domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Mal33_15070</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002327">
        <property type="entry name" value="Cyt_c_1A/1B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013427">
        <property type="entry name" value="Haem-bd_dom_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013428">
        <property type="entry name" value="Membrane-bound_put_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011041">
        <property type="entry name" value="Quinoprot_gluc/sorb_DH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11961">
        <property type="entry name" value="PTHR11961"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00034">
        <property type="entry name" value="Cytochrom_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50952">
        <property type="entry name" value="SSF50952"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02603">
        <property type="entry name" value="CxxCH_TIGR02603"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02604">
        <property type="entry name" value="Piru_Ver_Nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5" id="KW-0349">Heme</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="3 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022222825" evidence="6">
        <location>
            <begin position="24"/>
            <end position="1164"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="7">
        <location>
            <begin position="1028"/>
            <end position="1161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV55530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1164" mass="127428" checksum="C37BCB1A0C1B1531" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IR97</accession>
    <name>A0A518IR97_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose transaminase</fullName>
            <ecNumber evidence="4">2.6.1.90</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">fdtB</name>
        <name evidence="4" type="ORF">Mal33_15930</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the DegT/DnrJ/EryC1 family.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.90" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00616">
        <property type="entry name" value="AHBA_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000653">
        <property type="entry name" value="DegT/StrS_aminotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30244">
        <property type="entry name" value="PTHR30244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01041">
        <property type="entry name" value="DegT_DnrJ_EryC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000390">
        <property type="entry name" value="PLP_StrS"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="197"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="2">
        <location>
            <position position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR000390-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000390-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV55616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="377" mass="41276" checksum="16D285FCD65FE172" modified="2019-10-16" version="1">MIRQLDTDLEISSIPLVDLATQSRQIKEDVLRRMSDVIDSARYILGQEVQEFEEQFAAYCGVDHCVGLANGTDALHMALRALDVGEGDEVITAGNSFAATAFAIAYSGAQAVFVDIDPVDFNIDPNRIEAAITPRTKAIIPVHLYGQPAQMAAIREIADRHGLKIIEDAAQAHGAESNGQRCGSFGDIGCFSFYPGKNLGAFGDAGAAVTNDPELADRLRLLRNYGQKVKNRHDCLGYNCRMDTLQACVLLSKMQHIEDWTNSRRQVAAWYGEALAGTDLQLPVERDDARHVYHLYVVRHPQRDAIIESLAAKKIFCGVHYPHPLATATPFQDAKTFPEGLPVCTSAASAILSLPMYPEMTQQHVSMVAKALVDFGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRG8</accession>
    <name>A0A518IRG8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Natural resistance-associated macrophage protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_16740</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046873">
        <property type="term" value="F:metal ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001046">
        <property type="entry name" value="NRAMP_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01566">
        <property type="entry name" value="Nramp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="74"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="116"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="161"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="190"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="264"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="308"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="416"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="452"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="478"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="520"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="554"/>
            <end position="574"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV55695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="585" mass="62771" checksum="0808A006A64894A1" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRI3</accession>
    <name>A0A518IRI3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glutathione peroxidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">gpx1</name>
        <name evidence="8" type="ORF">Mal33_16790</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the glutathione peroxidase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004602">
        <property type="term" value="F:glutathione peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00340">
        <property type="entry name" value="GSH_Peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000889">
        <property type="entry name" value="Glutathione_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029759">
        <property type="entry name" value="GPX_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029760">
        <property type="entry name" value="GPX_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11592">
        <property type="entry name" value="PTHR11592"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00255">
        <property type="entry name" value="GSHPx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000303">
        <property type="entry name" value="Glutathion_perox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01011">
        <property type="entry name" value="GLUTPROXDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00460">
        <property type="entry name" value="GLUTATHIONE_PEROXID_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00763">
        <property type="entry name" value="GLUTATHIONE_PEROXID_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51355">
        <property type="entry name" value="GLUTATHIONE_PEROXID_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 5 8" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021892167" description="Glutathione peroxidase" evidence="6">
        <location>
            <begin position="25"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="7">
        <location>
            <begin position="22"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000303-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV55700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="186" mass="20412" checksum="84E6DB79BD943550" modified="2019-10-16" version="1" precursor="true">MSKISFSMLALSFLLGFAVNTANAHDHLTDFKMESIEGKTVDLAQFKGKAILVVNVASECGLTPQYEGLQALYEKYKDKGLVVLGFPCNQFHEQEPGTSAEIQSFCKSNYDVSFPMFAKVKVKGDDACPLYKHLTAADTKPKGAGKVSWNFEKFLVDGHGHVVGRYGPQTEPDDAALTQQIESLLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRP6</accession>
    <name>A0A518IRP6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_17440</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="117"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="148"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="187"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="219"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="274"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="300"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="335"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="364"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="545" mass="61304" checksum="BF02CD9D30834E40" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRR1</accession>
    <name>A0A518IRR1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Energy-dependent translational throttle protein EttA</fullName>
            <ecNumber evidence="7">3.6.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Translational regulatory factor EttA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ettA</name>
        <name evidence="10" type="ORF">Mal33_17570</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="7">Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="7">Associates with ribosomes and polysomes.</text>
    </comment>
    <comment type="domain">
        <text evidence="7">The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.</text>
    </comment>
    <comment type="domain">
        <text evidence="7">The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.-" evidence="7"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045900">
        <property type="term" value="P:negative regulation of translational elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00847">
        <property type="entry name" value="EttA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032781">
        <property type="entry name" value="ABC_tran_Xtn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022374">
        <property type="entry name" value="EttA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43858">
        <property type="entry name" value="PTHR43858"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12848">
        <property type="entry name" value="ABC_tran_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03719">
        <property type="entry name" value="ABC_ABC_ChvD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 7" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="6 7" id="KW-0810">Translation regulation</keyword>
    <keyword evidence="2 7" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="7"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="326"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="region of interest" description="PtIM" evidence="7">
        <location>
            <begin position="244"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7 8">
        <location>
            <begin position="39"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7 8">
        <location>
            <begin position="358"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV55778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="556" mass="62364" checksum="E81831180F1BA7F5" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRZ4</accession>
    <name>A0A518IRZ4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_18460</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021733749" evidence="2">
        <location>
            <begin position="24"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="314"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="333" mass="35902" checksum="9F16CB88688CF182" modified="2019-10-16" version="1" precursor="true">MRRTTFCTAALAASIFGFQAAKAQDVGDAVDGALNATGEAAADLGQEIGDAAEAAVPNQPAAEAPTDLDADADVEAKADVNADVDAKTQVQGDGPTAADVQTGTNTPLGVGVDENGNRPAGVDADAGINPQADLQSQQTRDSQALLQGDAALSGDAESQADANANAQANNDDNDKWRFRQHNDRWWYWLGDRGNGRWAYWDDGRWFDYTNNRYLNPRQQAGHHDGHQPRHRMGYRGDANNQGEFDGPYYFDRDGRRYRRDGDRYMNDSQWNDRVWDDGYGQRHQGYWNDRNNGRSSNGARAGASIGAGVGESIGGHAGGQIGAEIGGAIGRDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISF0</accession>
    <name>A0A518ISF0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase DDE domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_19620</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002559">
        <property type="entry name" value="Transposase_11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01609">
        <property type="entry name" value="DDE_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_1" evidence="1">
        <location>
            <begin position="90"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="459" mass="53459" checksum="54BA0F850BFAF6E1" modified="2019-10-16" version="1">MAIMEDSLPAIKSFLPNTQVSAHFRSMLLRFLIAILTRHGRNSCMSAASAIEGKPRHRAQPGRFLKRYRQAIADLLTAITLKMLRDQDWNGRYLLLLDSTLVATAGQTVENTFSTGNSKRRPAKNRCYTKYKYQRKSCHCFVFALLLTPDGLRVPMWLPYYTKPYAKTRKIKHRTQAQLAAQLICDAQVPAGIELIVLGDTAFDAKCVRAACRERGYFWIVPVNTNRVFAAKKHGKRPRVSLRIEQLPASRFQTIRLSIGSGPYAAQRRASCHRTARRRDGTKSTRTYHVHSERSEVHNVGMVMLVFSSSKPIGKKIQREGTKLLMTNAKHLSARQVCELYSLRWQIELFFKELKSTLGMNQYSFKDFEAVESWMGIVLITFCYLEWTRRRKLADRRIDDRQRKCWKHARSYTVREALLLGIRYREHQWHLRRLKTNHGLRTLRKRYTELLSQEYRCLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISF3</accession>
    <name>A0A518ISF3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF58 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_19900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002881">
        <property type="entry name" value="DUF58"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01882">
        <property type="entry name" value="DUF58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="domain" description="DUF58" evidence="2">
        <location>
            <begin position="213"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="453" mass="50239" checksum="D3572659970147EB" modified="2019-10-16" version="1">MNAAAPPADSRQAASEGSFKWIALGAAVLLVGMLFGSSLLLYTAYSAIAVVAVSRWLTNTWSVAPRAHRVSGPLEAEIGQVVPIEIEIQNTGKVLIPWLLAEDLLPRDALHYKVPALQIEGDRIRVISLSAGETDTIRYEIKCNRRGYYQIGPTVLETGDLMGLNRRYRVGAVPQYLLVMPRVVPLHGYDIQSRRPIGEIRMSHPLMDDPTRIVGIRQWQPGDPMRRVHWSATARTGELHSKIYEASSIAGATLVIDLHRDTNPRQHEPVRSELAITLAASISNALYQMNQPFGLVSNGRDAADRIRTEGFMTDYRTRDAATQHLKMHEVDAHLKPVCLSAQRGPVHYRDVHRMLARLEITDGLNLSQTFLEVESRLSRDTTLIVIVQKCDSSTAEVLAGFKRRGWAVTAIINTFEVDDYSKAAGPLVASGIAVMQLRDEASLAMICRALVER</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISL2</accession>
    <name>A0A518ISL2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_20540</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="60" mass="6760" checksum="7ADAE5CA5C8C5183" modified="2019-10-16" version="1">MEQQNATQPDLPTQTSGEETDESGDPNERKYQHEARASGFDTSTKRKRVIPATNQVIDRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IT11</accession>
    <name>A0A518IT11_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Trehalose utilization</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_22020</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029010">
        <property type="entry name" value="ThuA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06283">
        <property type="entry name" value="ThuA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022088958" evidence="2">
        <location>
            <begin position="21"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="ThuA" evidence="3">
        <location>
            <begin position="43"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="250"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF06283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV56221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="278" mass="31327" checksum="5D444D517F183A89" modified="2019-10-16" version="1" precursor="true">MVRLLICFSLVASTAMFAIAEPARLLMVSQSVGYRHSSVNREKMPLSPAERAITELGIASGLFRVDCTQDVATDFTKEKLQHYDLVLFYTTGDLPIAQEDLDYFFNDWLKQKGHGFIGTHSAADTFHNYKPYWDMIGGTFNGHPWGAGSTVTISVHDQDHPASKPWGEEVTLKDEIYRFKNWQPEKVRVLMSLNMAKTELKEPYHVPVLWVKEYGDGKVMHMSLGHREDVWTNETYLASLLGGMKWMLGQEPGDATPNPELSAAQELKAKADTEAAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITA7</accession>
    <name>A0A518ITA7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Nitrogen fixation protein VnfA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">vnfA_1</name>
        <name evidence="7" type="ORF">Mal33_23030</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002197">
        <property type="entry name" value="HTH_Fis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002078">
        <property type="entry name" value="Sigma_54_int"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025943">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025944">
        <property type="entry name" value="Sigma_54_int_dom_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02954">
        <property type="entry name" value="HTH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00158">
        <property type="entry name" value="Sigma54_activat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01590">
        <property type="entry name" value="HTHFIS"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
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</entry>
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    </evidence>
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                <person name="Peeters S.H."/>
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                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
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                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
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                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="1 2">Mal33</strain>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56415.1"/>
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        <source>
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</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITL5</accession>
    <name>A0A518ITL5_9BACT</name>
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                <person name="Rast P."/>
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                <person name="Jeske O."/>
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                <person name="Lage O.M."/>
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                <person name="Merkel B.J."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">Mal33</strain>
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    <evidence type="ECO:0000256" key="1">
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        <source>
            <dbReference type="EMBL" id="QDV56432.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
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    </evidence>
    <sequence length="143" mass="13977" checksum="F5CB088C8C7C2673" modified="2019-10-16" version="1">MLSSVLLSSVLLSSVLLSSVLLSSVLLSSVLLSSVLLSSVLLSSVLLSSVLLSSVLLSSVLLSSVLLSSVLLSSVLLSPVLLSPGLVSSVSVSPVLVSPGSVSSVSASSATAGASTLRSLTPLATVASVVVTTSSPVSSPLLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITR4</accession>
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        <submittedName>
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                <person name="Peeters S.H."/>
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                <person name="Rast P."/>
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                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
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                <person name="Merkel B.J."/>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="26"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="46" mass="4842" checksum="DF2E3FC88499B1E7" modified="2019-10-16" version="1">MSRGLNVVILAMQSGFLVFGLNESHLSMTAVAAFGVGFSLSVLVRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUK9</accession>
    <name>A0A518IUK9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_27720</name>
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        <lineage>
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            <taxon>Planctomycetia</taxon>
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    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="284" mass="30971" checksum="158D2D6F964A0AFF" modified="2019-10-16" version="1">MPYQANAYNVMIASPGDVARERVVARDVVLEWNAINSEDRQIVLLPIGWDTHSTPSMADTAQAVINSQVLERCDLLIAIFWTRLGTPTGEFASGTVEEIERHLASGKAAMIYFSNAPVVPDSIDQEQYAALVEFRESLKNRGLVSFYDDASAFRTDLFRHLSQTVIREFTGDQNGGVNPIAIPIPVERNELEISGAARELLFAAVGDAGGRIMNVRYLGGMEISTGGRNFIDDASPRTAAKWEGALDELENCGLIVARGTKREVFSVTEQGYAFAESLGVTPAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUR2</accession>
    <name>A0A518IUR2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_28000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="192"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="220"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="246"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="286"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="318"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="351" mass="39657" checksum="03E073AFC33CF19A" modified="2019-10-16" version="1">MHSILDALPQSSPQGGLSASADLPVPRSDSVRGWILGPWLDLLLVSNLFWPLLILLQHDDGFSGGMNIQFWQIYFITTPHRWSTLALVIVDRQQFRERPRFFIGFALFVILVCVGVRLGTGTLTCLLAIDYIWNAWHFAAQHHGIYRIYGRLSGASSRFPASVEKWILRSYLLYCILRVAQVAIEPGLTTDLLMIVDWIAPVLPGVILASELLQINRRSIGRVVYLASVLCLFTAMLWSVQAGNPALLLALATASAWFHASEYLAVVGWRLKKQNRFGERQASRTVLAWIASRWAISLMIFIVVLGSCGWMLEQRFLEFWLLINVIAAFLHYGYDGVLWRKRSSSVPKPVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUS4</accession>
    <name>A0A518IUS4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">HlyD family secretion protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_28380</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="domain" description="HlyD_D23" evidence="2">
        <location>
            <begin position="109"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="490" mass="54202" checksum="77FDE0DD111E4B9C" modified="2019-10-16" version="1">MGLRGKMQVIMQHVPSLTKLLFGLALAAGVALTTWYFRDALPFTGGVPAVAKEDPPQPASEKQTILEISVQARKNLRLTSQPARPQTYWRSLQIPGKLADRPGVSDRGVTSPAESVVTEIHISPGDAIRPGQRLFTLRLFSEYLQAAQTQLFKAKQETAIIQADIDRLSDAVTSGAVVRSKMIELQGNLRRQQILIEAARQDLRSRGLDSAQIEQIESGSFLSTIDVRAPEALPTVPLTETNADRVARTIQPVQQARFDSSSSRAPEFAFEVQELLVELGQQVQAGQPLATLANHQALYVVGHAFKREAPFLEQAAQEGRAIDIEFADDATDQWPELQQRFEIRHLSNAIDTNSRTFDFFIPLRNQSRAYQKAEQTFLVWRFRPGQRVRLHVPVEKLENVLVLPAAAVVRDGPEAYVFMQNGDLFKRLPVHVLHEDRQSIVLANDGSVTPGTYLAQNAAASLNRVLRSQAASGQQVGVHVHPDGTVHAAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUT0</accession>
    <name>A0A518IUT0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_28360</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022225732" evidence="2">
        <location>
            <begin position="19"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="175" mass="18191" checksum="3B1636297C7B027A" modified="2019-10-16" version="1" precursor="true">MKFTNWILSALLATGALGLTGCKPADTATGDATSAAESAADDHGHDHSGTDHSEAGHGHGVGPHDGTIADWGGGKFHVEFTVDHNKTEATVYVLGGDEKTAAPIAAESIELTIIDPEMQVTLKPSPQESDPDGTASRFVGTHEKLGVVQEYAGTMTGVIDGTPYTGEFKEEAHTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUV9</accession>
    <name>A0A518IUV9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">30S ribosomal protein S18</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3 6" type="primary">rpsR</name>
        <name evidence="6" type="ORF">Mal33_28820</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the bacterial ribosomal protein bS18 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00270">
        <property type="entry name" value="Ribosomal_S18"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0699">rRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV56881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="87" mass="10097" checksum="B584B637BB029026" modified="2019-10-16" version="1">MSTRSRARKRSRVRSRQKKQDPLFVDGTRPRPMYVDYKDVELLRRLVNRHGKIVGRRKSGCSATSQHAVTQAVKRARFMALLPFVGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IV12</accession>
    <name>A0A518IV12_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_29110</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043737">
        <property type="entry name" value="DUF5682"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18934">
        <property type="entry name" value="DUF5682"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="795" mass="87607" checksum="EB1B4F3BD2946FBA" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IV25</accession>
    <name>A0A518IV25_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytochrome c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Mal33_29430</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036280">
        <property type="entry name" value="Multihaem_cyt_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48695">
        <property type="entry name" value="SSF48695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022064083" evidence="5">
        <location>
            <begin position="25"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="6">
        <location>
            <begin position="54"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="6">
        <location>
            <begin position="163"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="6">
        <location>
            <begin position="296"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="6">
        <location>
            <begin position="502"/>
            <end position="596"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV56942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="835" mass="90816" checksum="9A8E266FA0509C28" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IV53</accession>
    <name>A0A518IV53_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein-glutamate O-methyltransferase</fullName>
            <ecNumber evidence="2">2.1.1.80</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">cheR2</name>
        <name evidence="7" type="ORF">Mal33_29460</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>L-glutamyl-[protein] + S-adenosyl-L-methionine = [protein]-L-glutamate 5-O-methyl ester + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:24452"/>
            <dbReference type="Rhea" id="RHEA-COMP:10208"/>
            <dbReference type="Rhea" id="RHEA-COMP:10311"/>
            <dbReference type="ChEBI" id="CHEBI:29973"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:82795"/>
            <dbReference type="EC" id="2.1.1.80"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.1.1.80" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008983">
        <property type="term" value="F:protein-glutamate O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.155.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022642">
        <property type="entry name" value="CheR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000780">
        <property type="entry name" value="CheR_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036804">
        <property type="entry name" value="CheR_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01739">
        <property type="entry name" value="CheR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00996">
        <property type="entry name" value="CHERMTFRASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00138">
        <property type="entry name" value="MeTrc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50123">
        <property type="entry name" value="CHER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CheR-type methyltransferase" evidence="6">
        <location>
            <begin position="1"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV56945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="279" mass="32603" checksum="2243FF066049324C" modified="2019-10-16" version="1">MKTLEVSNDIIDIIDVIEQLCGIQVDDRKLYLLEHRFGELMREASYSNYAELARCARDDRQLQQQIVERITTRETLFFRDGSPFQALQHKLLPEIIDARASSRFPRRLRLWSAACSSGQEPYSLAIMLRELLPDADNWDVQILASDISSTAITQAKQGVYSEHEISRGLSPAQLNRYFHKEGNLWRVQDKLRSMIRFEERNFLQPFTNVGMFDVVFCRNLAIYFSDGNRKDLFNRIANQMVDDGLLFIGAQEYHSDMSQRFTMEHHCRATVYRPKKRVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IV57</accession>
    <name>A0A518IV57_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DinB superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_29780</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024775">
        <property type="entry name" value="DinB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12867">
        <property type="entry name" value="DinB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DinB_2" evidence="1">
        <location>
            <begin position="21"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="175" mass="19090" checksum="3D7C5EC603CF173A" modified="2019-10-16" version="1">MSTFIGNMIADSLARGISYADSLVKDLPADQFARFAPGKEGPIVSNHPAFILGHLSIYAPRVVEQLGQDATAYQPTEAENALFSPAAKCQDDPNGLIYPGKDQLVDRFTTVYQAALTTLRNATDDQFMVPNPAEGRLRELFPTLGGIHAFYTGGHFMLHMGQLSAWRRMMGMAPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IV90</accession>
    <name>A0A518IV90_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_29990</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="198" mass="22026" checksum="6A47B9FAA432B402" modified="2019-10-16" version="1">MTTRDGCIEGQQPPDLEKGDTVTRGRFLRNLKKKGEATKRYPGDNDENPLYGLKLSTKFWKNASGNGDMSINEQACVSSDVCSIEIHPNSQQYYHVAVLNLAEINRVMGEHIFVAQYLPLKDPPHGPNACHFELLPLNGSTQSLFALQTELDKPFPPGKMPDGNDNEIAAKTATAEYQEIVVIRRWVRNQNGALSPNC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVD6</accession>
    <name>A0A518IVD6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_30470</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="287"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="288"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="312" mass="33595" checksum="47F28089866DF5DC" modified="2019-10-16" version="1">MPRLSIIIPLRSHSEDFETTLVSVLENRPDDCEVIVAHDGNYEDPFELAGEVCFAVGNDCTLLNLVRAGSEIATSPIVHVLADGFQATSGWTDSIDETFADHDVACASPLVCDMDDHDLILAAGWTTNALRLRRPIAHGATAVGRLEADRISGLFLAASFWRVSALRQCLKASSVATAVDFEAFASRWVKKAAYDIQIAGESRVTTYEDAVEIESVGFRTGYQLQSAGPASGAAATIGFAMLSCLTQPHRIGTWTTAAGRVAASILAGKRRQEIDRDLRKLASASIESPQAFEESQPQTLAFPVSEPLRRAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVE6</accession>
    <name>A0A518IVE6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminotransferase</fullName>
            <ecNumber evidence="1">2.6.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_30540</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.-" evidence="1"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.109.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012825">
        <property type="entry name" value="BluB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004838">
        <property type="entry name" value="NHTrfase_class1_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029479">
        <property type="entry name" value="Nitroreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000415">
        <property type="entry name" value="Nitroreductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00881">
        <property type="entry name" value="Nitroreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55469">
        <property type="entry name" value="SSF55469"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02476">
        <property type="entry name" value="BluB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00105">
        <property type="entry name" value="AA_TRANSFER_CLASS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="3">
        <location>
            <begin position="30"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="domain" description="Nitroreductase" evidence="4">
        <location>
            <begin position="388"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV57053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="580" mass="63990" checksum="36705C31202CF46E" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVL6</accession>
    <name>A0A518IVL6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">zinc-ribbon_6 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_31330</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031321">
        <property type="entry name" value="UCP012641"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011201">
        <property type="entry name" value="Zinc-ribbon_6_bact"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15887">
        <property type="entry name" value="Peptidase_Mx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10005">
        <property type="entry name" value="zinc-ribbon_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF012641">
        <property type="entry name" value="UCP012641"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="zinc-ribbon_6" evidence="1">
        <location>
            <begin position="4"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="342" mass="38601" checksum="81A768EAC9380902" modified="2019-10-16" version="1">MRSFYCQCGSTLFFGSVQCVACSRPTAMCPHCNAVRSMAVADDGSLVCDHCHRECRMCSNATQHAVCNRGVDAASEQPLCRYCRLNSVVPDLTVGDNLLKWQRLEAAKHRVLFDIERIGLPIVSEPENESGSSDGRPVLQFEFKSSAVKPVSTGHADGLITIDIAEADSVHREQTRVEFGEPQRTLVGHFRHELGHYYWQLLVEPNCLDAFRSLFGDEREPSYAEAQKRYYADGAIPDWQDRFISAYSTMHPWEDFAETFAGYMDIVAVVETARHFDRTRVTADGSDFNQMLTAYRDIGIVANEFNRDMGLLDLVPEFHSEAVVEKLKFIDNLRLTLQKEPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVN3</accession>
    <name>A0A518IVN3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Sialic acid transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">nanT</name>
        <name evidence="7" type="ORF">Mal33_31440</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="62"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="93"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="118"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="152"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="179"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="236"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="277"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="310"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="336"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="369"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="401"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="22"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV57143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="430" mass="46755" checksum="544746528C3567C2" modified="2019-10-16" version="1">MSSPQTDTTRWYSGISRYQWLVLIIASAGWVFDVYEGQIFNITRGDMLSELLDGDQAAVKGWGDRFLAIFLLGGTVGGLVFGSMADRYGRRPILIVTILLYSVFSGLTYFATDIYQVGVLRFLVALGIGGEWAVAASMVAEVFPSKARAQAAGIFHASSILGTWLAALAGILVATQWRYAYLLGVLPALLIVWVRASVKEPERWQKQVDEDDPQSNKHLAGSFRDLLLNPRWSGRAFGGLLLAAVGLGTFWSVTVAGQDLVKELLLRTGTAAEDVGGMAKFAYGIVQASGGGLGLLAFGPIAARFGRKPAFVGFQLLALLIVPVVCFVPQSYTQMLFILPVFGFLTLGMHAGYAIYFPELFPTHLRATGASFCFNGGRMLAVPVLLFSGWLKEQPDMQLRYAVLGLSTLFLVGVVVVLMMPETRNQELPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IW88</accession>
    <name>A0A518IW88_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_33640</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="59"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="166"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="195"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="217" mass="23863" checksum="A585367253CE480A" modified="2019-10-16" version="1">MSSSRSENKPSAIHPGPGDRVVEVDGQTVYLRKPALAAVLAWLIPGAGHLYQGRTRKGWMFMICILVTYFFGFAIGGGHVVYASWINGDKRWHYLCQLPVGLVAFPALIEGNNMRKHTVRGVTTADWKPYFGELMSPPRRPLQENDADDLASWYAQRGAGYEMGTWYTMIAGLLNVLVIFDAFAGPLAIPISGKSERSPKDEKEGDESEANSQEGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWP0</accession>
    <name>A0A518IWP0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_35130</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010496">
        <property type="entry name" value="3-keto-disaccharide_hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06439">
        <property type="entry name" value="DUF1080"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021703720" evidence="1">
        <location>
            <begin position="31"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1080" evidence="2">
        <location>
            <begin position="35"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1080" evidence="2">
        <location>
            <begin position="253"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1080" evidence="2">
        <location>
            <begin position="456"/>
            <end position="688"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="704" mass="78652" checksum="36E7F6957447FBE6" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IX23</accession>
    <name>A0A518IX23_9BACT</name>
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        <submittedName>
            <fullName evidence="5">Translation initiation factor Sui1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_36500</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
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    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="SUI1_arc_bac"/>
    </dbReference>
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        <property type="entry name" value="SUI1_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="SUI1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Transl_init_SUI1_pro"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SUI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0810">Translation regulation</keyword>
    <feature type="domain" description="SUI1" evidence="4">
        <location>
            <begin position="42"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV57637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="113" mass="12341" checksum="3B77C65F7618894D" modified="2019-10-16" version="1">MRLFAGTQFDIPPTCDRCGALEQDCKCPPLPPPKLDPQKQTARLMTEKRKRGKVVTLIKGLPAEGNDLPALLTKLKSRCGAGGTIKEDQLEIQGDHLETARSVLSEIGFRTKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IX38</accession>
    <name>A0A518IX38_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative HTH-type transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_36590</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00778">
        <property type="entry name" value="HTHARSR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50987">
        <property type="entry name" value="HTH_ARSR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="12"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="105" mass="11786" checksum="199A8D34A9843FC7" modified="2019-10-16" version="1">MTAAKKQTKPRGSVQDFSAAAECLKTLAHPVRLRIVQMLLHGRYTVGELAADCEIPDNVGSEHLRLLQRCGFLDSQREGRRVYYSVAEPHLSQLMACIEGRFLTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IX67</accession>
    <name>A0A518IX67_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_36890</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011444">
        <property type="entry name" value="DUF1549"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022655">
        <property type="entry name" value="DUF1553"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07583">
        <property type="entry name" value="PSCyt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07587">
        <property type="entry name" value="PSD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021864944" evidence="1">
        <location>
            <begin position="21"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="domain" description="PSCyt2" evidence="2">
        <location>
            <begin position="231"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="domain" description="PSD1" evidence="3">
        <location>
            <begin position="474"/>
            <end position="707"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV57676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="735" mass="82309" checksum="6C34293055D0DB43" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXC4</accession>
    <name>A0A518IXC4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">LapA_dom domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Mal33_37580</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010445">
        <property type="entry name" value="LapA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06305">
        <property type="entry name" value="LapA_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="domain" description="LapA_dom" evidence="6">
        <location>
            <begin position="23"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF06305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV57744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="82" mass="8823" checksum="56C93B585907F889" modified="2019-10-16" version="1">MARLKLILVVSFLLLLVIIAYLNRGKVALNLLFSEFEVPVTILICVTALIGFAVGVVFGARIPRKLKVTGVPADSKNSAKAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXE2</accession>
    <name>A0A518IXE2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative 2-keto-3-deoxy-galactonate aldolase YagE</fullName>
            <ecNumber evidence="3">4.1.2.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">yagE_3</name>
        <name evidence="3" type="ORF">Mal33_37730</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the DapA family.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.-" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002220">
        <property type="entry name" value="DapA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020625">
        <property type="entry name" value="Schiff_base-form_aldolases_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00701">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001365">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00146">
        <property type="entry name" value="DHPICSNTHASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01130">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00666">
        <property type="entry name" value="DHDPS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0704">Schiff base</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR001365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="314" mass="34253" checksum="08AB780983B17C78" modified="2019-10-16" version="1">MPSSPTTQPPSRFQGIVPPIVTPLADDDRLDDSGCERLLEHQIEGGVDAIFLLGSSGEIVSLSHQLRADFVRKACRIVNQRVPVLVGITDNSVVETKRLAQVAADAGADAVVLTTPFYYPVDQAELKTFVQSILQGIDLPLLLYNMPAMTKLWFAPETVAELAQIDQIVGIKDSSQNLDYFRQLTSLKSIRPDWTFLIGHETLLADSLRVGGTGGVNLGTNLFPKLFSRLMQAHRENDDDAVQGFQTKIDALAPIYEIANSSAPLLPLIGITKTALSILGICNDHLAPPHRPCTPEQRQQLTVVLEQLKSTLGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXQ5</accession>
    <name>A0A518IXQ5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Malto-oligosyltrehalose trehalohydrolase</fullName>
            <ecNumber evidence="2">3.2.1.141</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">4-alpha-D-((1-&gt;4)-alpha-D-glucano)trehalose trehalohydrolase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Maltooligosyl trehalose trehalohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">treZ</name>
        <name evidence="7" type="ORF">Mal33_38900</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Glycan biosynthesis; trehalose biosynthesis.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.141" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00299"/>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033942">
        <property type="term" value="F:4-alpha-D-(1-&gt;4)-alpha-D-glucanotrehalose trehalohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005992">
        <property type="term" value="P:trehalose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="Glyco_hydro_13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006379">
        <property type="entry name" value="HAD-SF_hydro_IIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006380">
        <property type="entry name" value="SPP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012768">
        <property type="entry name" value="Trehalose_TreZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044901">
        <property type="entry name" value="Trehalose_TreZ_E-set_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05116">
        <property type="entry name" value="S6PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="SSF81296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01484">
        <property type="entry name" value="HAD-SF-IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02402">
        <property type="entry name" value="trehalose_TreZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aamy" evidence="6">
        <location>
            <begin position="392"/>
            <end position="738"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00032057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00033284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV57875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="878" mass="98352" checksum="85215B0985CFF5AF" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYC2</accession>
    <name>A0A518IYC2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Acetyl-CoA acetyltransferase</fullName>
            <ecNumber evidence="7">2.3.1.9</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">thlA_3</name>
        <name evidence="7" type="ORF">Mal33_41030</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the thiolase-like superfamily. Thiolase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.9" evidence="7"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003985">
        <property type="term" value="F:acetyl-CoA C-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00751">
        <property type="entry name" value="thiolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002155">
        <property type="entry name" value="Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020615">
        <property type="entry name" value="Thiolase_acyl_enz_int_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020610">
        <property type="entry name" value="Thiolase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020617">
        <property type="entry name" value="Thiolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020613">
        <property type="entry name" value="Thiolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02803">
        <property type="entry name" value="Thiolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000429">
        <property type="entry name" value="Ac-CoA_Ac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01930">
        <property type="entry name" value="AcCoA-C-Actrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00098">
        <property type="entry name" value="THIOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00737">
        <property type="entry name" value="THIOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00099">
        <property type="entry name" value="THIOLASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thiolase_N" evidence="5">
        <location>
            <begin position="8"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="Thiolase_C" evidence="6">
        <location>
            <begin position="289"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="3">
        <location>
            <position position="92"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="384"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000429-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV58086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="427" mass="44608" checksum="A898E04620322888" modified="2019-10-16" version="1">MNQSIQPIAILAGQRTPFAKAYGAMNDVSAAALGQAAVTAALGKANLIPDQVDELVFGNVAGPADSANIARVVSLKAGIPADRIAHTVNRNCGSGMESILSGWQIVREARARIVVAGGTESMSGIPLLVRPSAAKLLMQLNRSKRIGAKLAILAKLRPKHFKPVAGVMLGLTDPVSGLNMGETAEVLAKEFAISRDDQDSFALQSHQKAVAAREQCFLSGEITPIEIAGRTVEKDDGPRANQSIEQLRKLKPIFDPAGTVTAGNSCPLTDGAAAVVLVDADDELAKSQPPLGRITAYAIAGCDPRRMGLGPVYATAKLLNQTGLTLADFDLFEINEAFAAQVLACLAAMQSTAFARQELGLSSPLGEIPIDRLNVHGGAIALGHPVGTTGTRMVITLLRSLRERGLQRGLATLCIGGGQGFAMVVET</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYH0</accession>
    <name>A0A518IYH0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative ECF RNA polymerase sigma factor SigI</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">sigI</name>
        <name evidence="5" type="ORF">Mal33_41470</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="3">
        <location>
            <begin position="32"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="4">
        <location>
            <begin position="134"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="384"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV58130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="434" mass="48120" checksum="B7288E116C3669C6" modified="2019-10-16" version="1">METNRSDNKSTTEPADGTAAKNRETDAIEEAYRTHSRAVFATLVRLIGDFDLAEEALHEAFIAALEKWQQQGIPADPRSWLVSSGRFKAIDVIRRRARFHRAADELAQRIEEIAAANASVSEREIQDDRLRLIFTCCHPAIDPKVQVPLTLREVCGLTTEEIASAFLASPSTMAQRIVRGKAKIRDAKIPFVVPSLTELPERLDAVLSVVYLVFNEGYSASTGESLTRPDLSQEAIRLSRLIVELLPDPEAMGLLAMMLLHESRRQARLTPDGDLVLLEDQDRSLWDRDLIDEGKLWVQRSLESRRVGGYAIQAAISAVHADAVTADATDWPQIVALYGVLMQATPSPVIELNRAVAVAMADGPAAGLEIIDAILQRGELQGYRLAHAARGELLRRQGQIDAARAAFRRALELATQEPERRFLTRKLDALDQVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYS9</accession>
    <name>A0A518IYS9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hydrogenase transcriptional regulatory protein hupR1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">hupR1_1</name>
        <name evidence="3" type="ORF">Mal33_42600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="4"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="391" mass="42668" checksum="A131B903CB573BA6" modified="2019-10-16" version="1">MTLRVLFVDDNQKVLNSIARQFEGVLDYETANGPHEAIELLDPENPFAVVVSDMRMPKMNGAELLTHVRKVSPETVRIMLSGYADLQATIQAVNEGNIARFLSKPCPRELLERAIREGLDQYQLVTGQRELLEGTLQGSVTVLCAILSLVHPLAFGRVSQVQRIALAIGDQMQLESIWDLKIASMLFPLGCVSLSERALECMLEGIPVPSEERSAYEQHPSVARAMLQEIPRLDNVAAIVAYQEKGFDGSGLPIDEIAGTDIPIGARVLKAALDFEIAMKQTSDATTALEKLLQSPAGYDPEVLDALRQQIEAGFCQRSQRTVPLAELRTGMVLAADVRLEGGKLVAASGQEVTDSIRRNLETFCEFGQIEGSFEIESVGGAENAECEAVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYY5</accession>
    <name>A0A518IYY5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RES domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_43200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014914">
        <property type="entry name" value="RES_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08808">
        <property type="entry name" value="RES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00953">
        <property type="entry name" value="RES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RES" evidence="1">
        <location>
            <begin position="34"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="184" mass="19629" checksum="4EAD061DD4D3E533" modified="2019-10-16" version="1">MDQDSIQRLAKFAHAFAAPIYRSVSIRHSRSKGILSGEGSFRFGGRWNPPGLRATFGALTPEVAMAETLAAARYHGLAAHTVMPRIFVAIHVQLSFVLDLTAANVQAAGRFRSSRFTHVDWRANVDKGQMPATQAIGSAAAAIGLEAILVPSAAATKGRNLVVFVDNFVGSSLVEVLSANDLEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYZ0</accession>
    <name>A0A518IYZ0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Prolyl oligopeptidase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_43180</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021995184" evidence="1">
        <location>
            <begin position="19"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S9" evidence="2">
        <location>
            <begin position="104"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="318" mass="34487" checksum="5AC8C23FED006D3F" modified="2019-10-16" version="1" precursor="true">MKIASLLLCLLLVSVTNPQIVCGQKASEIRYLSSADKTEQPAMFYSPDSESAVPLVVALHSWSGDYKQRLHQEIEAWCIEQGWAYIHPNFRGPNLRPEATGSELVVQDIVSAVDHAKMTANIDPSAVYLIGTSGGGYASLLMAGRHPEIWAGVSAWVPISDLTAWYHECKLAKRNYFNNIAASCGGAPGTSPEVDEEYRKRSPLTYLADAKGVRLSINAGIRDGHVGSVPVSHSLLAFNEVADAADRLSEEQIREFVQTAKVPADLQTAISDPSFGEKQPLFRRTSGSATVTLFDGGHELVDNAAIAWIKQTYAAKGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYZ6</accession>
    <name>A0A518IYZ6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Histidine-specific methyltransferase EgtD</fullName>
            <ecNumber evidence="4">2.1.1.44</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">egtD</name>
        <name evidence="4" type="ORF">Mal33_43330</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.1.1.44" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030745">
        <property type="term" value="F:dimethylhistidine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035094">
        <property type="entry name" value="EgtD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019257">
        <property type="entry name" value="MeTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017804">
        <property type="entry name" value="MeTrfase_EgtD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10017">
        <property type="entry name" value="Methyltransf_33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018005">
        <property type="entry name" value="UCP018005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03438">
        <property type="entry name" value="egtD_ergothio"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_33" evidence="3">
        <location>
            <begin position="27"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF10017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV58315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="328" mass="36565" checksum="2D58D7E571FBC588" modified="2019-10-16" version="1">MQPLHRFPATQPHCSTATADASDAEFLQDVLAGLSKSQKHLPCKYFYDERGSKLFDQICELDSYYPTRTETGIMVDNAEAIGRRLGPEAVLVEYGSGSSTKTRQLLDHLQNPTAYIPVDISEDHLLATAERLKADYPDLDIHPIVADFTQGFEIPTAYRNSQLTVYFPGSTIGNLEPDAAIELLRTIARQCDSHGGLLIGVDLDKAEQVLLDAYDDDLGVTAEFNLNLLHRINRQLNGNFAVDKFRHVAIYNAAKARIEIYLESHCAQTVAIGDAQFTFAEGERILTEYSHKYDVSSFADLARHAGLSVDEVWTDPRDYFAVMHFSAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ04</accession>
    <name>A0A518IZ04_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Y1_Tnp domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_43410</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002686">
        <property type="entry name" value="Transposase_17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036515">
        <property type="entry name" value="Transposase_17_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM01321">
        <property type="entry name" value="Y1_Tnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143422">
        <property type="entry name" value="SSF143422"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Y1_Tnp" evidence="1">
        <location>
            <begin position="13"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="359" mass="40724" checksum="05C0DC6E16B35940" modified="2019-10-16" version="1">MARQARGEVIDPEQVQIVHCIERCVRRAFLCGGDPDTGQSFQHRRGWIRERLEFLASCFAIDCLTFSIMSNHLHLVLRSRPDVVAAWSDEEVARRWLRLFPIRHNDDGSPAEPSAAEIAAIVNNEQVLAQRRRRLSDISWWMRCTAENIARRSNAEDDVSGHFWEGRFKAQLILDEASLMACAAYVDLNPIRATIAQTLESSEYTGAKERIDDITCASEQNRQHVHDWERSRIPYNSGWLSPVEINERDDPIGADIDSSHRRSSCKGFLSISLSKYLALIDWTGRQLRDDKRGSIPAELAPILTRIGLDAPAWCDLVKRFGRLFKRAAGTSQSLCQEAARRRQAWMQAPQNPLVGPAPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ27</accession>
    <name>A0A518IZ27_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF374 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_43560</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd07983">
        <property type="entry name" value="LPLAT_DUF374-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007172">
        <property type="entry name" value="DUF374"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04028">
        <property type="entry name" value="DUF374"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF374" evidence="1">
        <location>
            <begin position="65"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="261" mass="29317" checksum="3ED712FEDB3EE951" modified="2019-10-16" version="1">MKLTSGWIGGSLSLGMSIAVRTWMKTLRFQISYYDSSYDPANASYTTPGIYIFWHEYIPFMFYLRGHNDVAMLLSQHRDAETLARATRFVGFGTIRGSTSRGGITALRKMFRQGKTMNLTMTPDGPRGPRRELAAGCVYLASRLQLPIIPLGLGYDRPWRMRRAWDQFAVPRPGSRARAIMGPGIWIPAKADREQLETHRRQVETVLNRLTVEAEQWAETGQAVGNPVVITRTPRALTWMRGAAEPAIAKLDDASRRGVAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ30</accession>
    <name>A0A518IZ30_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative ABC transporter ATP-binding protein YbhF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ybhF_6</name>
        <name evidence="6" type="ORF">Mal33_43610</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025302">
        <property type="entry name" value="DUF4162"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13732">
        <property type="entry name" value="DUF4162"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="11"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="43"/>
            <end position="50"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV58343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="317" mass="35485" checksum="9A71570F946F1401" modified="2019-10-16" version="1">MIGYHVDDSVIELRRLHRNFGKTRAVNDVSFSVPRGTVFGYIGPNGAGKTTSMRILATLELPTLGDAYVDGFSVVNDPDHVRRRLGFMPDAFGTYPSVNCMEYIDFYARAYGLAGRERHQRVRWVMDFTRLDGIAEKPIRGLSKGMKQRLCLGRALVHDPAVLILDEPAAGLDPRARIELRRMIRALADDGKTVLVSSHILTELAEMCDRVGIIEQGRLLATGTVDEIQRQQRTHREFIVRVIDHLDVATNLLTHNEHVDHLVVDGELVRFQFEGDITRQANLLASLIAAGVSVAEFSSHVRSLEDVFMQVTEGLVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZA8</accession>
    <name>A0A518IZA8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_44440</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="51"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="274" mass="30530" checksum="1A522F597D680D76" modified="2019-10-16" version="1">MARRPRTNDDDISLFPFLSIVACVIGVLTMMIATLALAQTDSPDIAQIEEYETVQKKQKEADESIQQLQQRISVSNSAALHLKETQQERKLTQAELEELLKETEELEKQLEEQKKMEVVIPQVNPKDRETIGDMQTELSAVQEELAQLEAQLQKRKDVPTEGNVTVLPQGSGLSFTPHFVECAEGALVMHNLSPPKRIRTAEAAGDKDFKALMNKVLNGKDDSIVFLVRSDGLSTYRTLKGLCDANDLRNGKIPVVGKGRIDLSVFTEEQSKAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZD6</accession>
    <name>A0A518IZD6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Zinc-type alcohol dehydrogenase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_44640</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002364">
        <property type="entry name" value="Quin_OxRdtase/zeta-crystal_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01162">
        <property type="entry name" value="QOR_ZETA_CRYSTAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKS_ER" evidence="1">
        <location>
            <begin position="30"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="332" mass="35706" checksum="E1041F0BCA7FC186" modified="2019-10-16" version="1">MSTQYREADATASERPIGQTMQAIVYDDYGEADVLHRAELPIPRRLPGQLLLSVAASSVNPIDYRLRRGEMKGLLPFGFPRIPGYDIAGTVADCAPDAPFKPGDRVIAYLDYIRGGACADFAACSVGVAARIPDTLPTEEAAAIPLAGTTALQSLRDHGKIRAGQRVLINGASGGVGMFAVQVAKSYDCHVTAIASGANEDFCRELGADVFYDYNKIDFTKAGERWDLIFDAAGKSGYLEARAVLTDSGRFVSTEPDVQGIMMSLLTTPLSKRGKVMLAKPCGDDLRALIGLYELGRLKITLDSQFPMSETAAAHRRIEQGVDRGKVVLINS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZD9</accession>
    <name>A0A518IZD9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ATP-dependent helicase HepA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_44820</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140658">
        <property type="term" value="F:ATP-dependent chromatin remodeler activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
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    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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            <end position="836"/>
        </location>
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            <end position="1119"/>
        </location>
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        <location>
            <begin position="1"/>
            <end position="21"/>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="QDV58459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1125" mass="125642" checksum="2442F7D94BC797E5" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZZ5</accession>
    <name>A0A518IZZ5_9BACT</name>
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        <submittedName>
            <fullName evidence="2">Inner membrane protein YiaW</fullName>
        </submittedName>
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        <name evidence="2" type="primary">yiaW_2</name>
        <name evidence="2" type="ORF">Mal33_46900</name>
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        <name type="scientific">Rosistilla oblonga</name>
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
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        </location>
    </feature>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="QDV58666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
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        <submittedName>
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        <name evidence="5" type="primary">drrA_2</name>
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.6.3.-" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        </location>
        <ligand>
            <name>ATP</name>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV58678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="258" mass="28793" checksum="75BBF0A882A5D07F" modified="2019-10-16" version="1">MIEVSELTKAYDDLQKGKFIAVDSVSFSVGPGEIFGLLGPNGAGKTTVLRILSTVLQATSGIARVQGYDVSADPAAVRRRIGFVSNNTAVYDRMTAWEMVEYFGQLHGMPRDALDARLVELFAQLRMDDFRHVPGAKLSTGMKQKVSIARALVHDPPVLIFDEATLGLDVLVARNLLQVIRSLKDAGKCLIFSTHIMREVERLCDRIAVMHRGRILDTGTLAELRERHSQHDFEELFFDLLSQHEAEHDDPEYDLKAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J031</accession>
    <name>A0A518J031_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Serine-aspartate repeat-containing protein C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">sdrC_2</name>
        <name evidence="4" type="ORF">Mal33_47300</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Rosistilla</taxon>
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    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002105">
        <property type="entry name" value="Dockerin_1_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036439">
        <property type="entry name" value="Dockerin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033764">
        <property type="entry name" value="Sdr_B"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00404">
        <property type="entry name" value="Dockerin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17210">
        <property type="entry name" value="SdrD_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63446">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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    <feature type="domain" description="SdrD_B" evidence="3">
        <location>
            <begin position="248"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
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            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="138"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV58706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="852" mass="91371" checksum="672DE0BC872EB503" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J037</accession>
    <name>A0A518J037_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Formylglycine-generating sulfatase enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_47310</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005532">
        <property type="entry name" value="SUMF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042095">
        <property type="entry name" value="SUMF_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03781">
        <property type="entry name" value="FGE-sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="SSF56436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FGE-sulfatase" evidence="1">
        <location>
            <begin position="60"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="244" mass="26261" checksum="2B529BBBBFDE02F9" modified="2019-10-16" version="1">MKRICICFLLGFAGCQQQVSDNRDEPDTGLVFASSQDGAITNLFGMKFVPVTIEKSVEGHSRTFMMQTHEVTVAQFQSVIEPLGNSGIKAIDEVDGSKLIQGFDSWNAAENFTRTISRLDAKHSYRLPTEAEWKAGCAGQIVAPPSPGSDTGPVNAVGTLRHENAFGLHNMLSGLAEYTSSDFVEGDAPAGMGIAEGNDAKVVMGDQVWSESLGQFQRGCDQRKPISMTGDSLTIGVRLIAENR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J086</accession>
    <name>A0A518J086_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Fic/DOC family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_47400</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003812">
        <property type="entry name" value="Fido"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036597">
        <property type="entry name" value="Fido-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040198">
        <property type="entry name" value="Fido_containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013436">
        <property type="entry name" value="Mobile_mystery_prot_B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13504">
        <property type="entry name" value="PTHR13504"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02661">
        <property type="entry name" value="Fic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140931">
        <property type="entry name" value="SSF140931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02613">
        <property type="entry name" value="mob_myst_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51459">
        <property type="entry name" value="FIDO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fido" evidence="4">
        <location>
            <begin position="65"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="139"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="143"/>
            <end position="150"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR640198-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR640198-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV58715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="211" mass="23642" checksum="AF879613C7D883A7" modified="2019-10-16" version="1">MNPGRGKATGLGSSGKDDDTPFDGSGLKLKTIKTRRELNEVEFSSILRVTEKYLLSKPSRRIAPFSFDWLLGLHREMLGSIWSWAGEIRSTEKNIGVSPNIIAAELGVIAMEADKRHNETGALVIATAAEFHHRAVWVHPFEDGNGRWARLLANVWLMQHDQPATLWPATDLRNTESPIRDEYIAAIKEADARNYGPLIDLHQRFSEGTQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0C2</accession>
    <name>A0A518J0C2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Fatty acid hydroxylase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_48030</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008610">
        <property type="term" value="P:lipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006694">
        <property type="entry name" value="Fatty_acid_hydroxylase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04116">
        <property type="entry name" value="FA_hydroxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="180"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="228"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="domain" description="Fatty acid hydroxylase" evidence="2">
        <location>
            <begin position="250"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="397" mass="44952" checksum="96C91D1135F3E0A6" modified="2019-10-16" version="1">MNTANTKPQQLLHSPPAGAEYRLFGAAGTGGAYNSHFVAGAIFIGLAAVGAIDWWLAIWLDSCLAIGLLLDRRTMNRKLALRAMPGQMLLYSQVALRAAVHLLPYYLFAFVLYLGMAPVILPLNFAISSFAMLYGFYMAIRIYWLVRYLWVLHFHWERAGRTFQTHQANLKTRSSAIRHVLWAFFLGNVGLVVRCSSQVITIAGFEYLRQRMNLDLTKHPDLSGHMMTIFWVTTAIWLATFWFALQPAFLIYYRVHRTFHTCRPLYDSVHSIHHRGVLPTQLDSGTISPLEFALTELNLPAATLVPNWYWTLGQIILALAGHFPSHDTNTWMKTGHHHLLHHRLFNVNFGLIAREDKRYGSYYCEPSKATAPSSGPVEADLPPPWRQAVAAMAGEDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0K6</accession>
    <name>A0A518J0K6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mannosyltransferase putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_48980</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006486">
        <property type="term" value="P:protein glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022751">
        <property type="entry name" value="Alpha_mannosyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11051">
        <property type="entry name" value="Mannosyl_trans3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="463"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="463"/>
            <end position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="778" mass="89214" checksum="E5F336398A09D444" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0R7</accession>
    <name>A0A518J0R7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_49470</name>
    </gene>
    <organism evidence="1 2">
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        <dbReference type="NCBI Taxonomy" id="2527990"/>
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            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
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            <strain evidence="1 2">Mal33</strain>
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    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
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            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="203" mass="22764" checksum="214C49D30F3DDC63" modified="2019-10-16" version="1">MVALATAHRALWKLKSKMIPASYFHQGLPYDDFLAKHGSDLDRRKWAAVYDVCELSDAQTALIGGFVREMRVLCFAGAWCGDCVQQCPILRRIEQASDKITVRYIDRDASDELKGIMSICGAARVPQVAFFSEEDFFVGHYGDRTLARYRQMADQLAGAACGSGIVTADDPVQAAVIQEWINEFERPQLMLRTSARLREKHGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
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    <name>A0A518J0T6_9BACT</name>
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        <name evidence="5" type="primary">mrpD_2</name>
        <name evidence="5" type="ORF">Mal33_49730</name>
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
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            <topology evidence="1">Multi-pass membrane protein</topology>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="match status" value="1"/>
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            <dbReference type="EMBL" id="QDV58948.1"/>
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        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
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    </evidence>
    <sequence length="542" mass="58034" checksum="81DC62601BC7CAC1" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0W7</accession>
    <name>A0A518J0W7_9BACT</name>
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            <fullName evidence="3">Glycosyltransferase EpsD</fullName>
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    <reference evidence="3 4" key="1">
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            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
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                <person name="Bruemmer F."/>
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                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 4">Mal33</strain>
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    </feature>
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            <dbReference type="Pfam" id="PF13439"/>
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        <source>
            <dbReference type="EMBL" id="QDV58986.1"/>
        </source>
    </evidence>
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    <sequence length="407" mass="44293" checksum="FD9B1DA19D4140CA" modified="2019-10-16" version="1">MIRLSRRPQPRNRRGPLKTMFVITSMPVGGAETLLVNMIDRFDRNRIVPEVCCLKEPGPLGEAIRDRVEVHSHLLSSKFDPRTLPRLISMFRRQQIDAVVTVGAGDKMFWGRLAAWFAGVPVIASALHSTGWPDGVGRLNRLLTPITSAFIGVAASHADYLREQEGFPDAKVFAIRNGVDVQRFAPDPDAASAVREELHIPSDAPLGIIVAALRPEKNHAMYVDVARRVSQQIPGSHWLIVGDGPERPAIEAACSEAGVSDRVHLLGTRHDTPRLLAASNLFLLCSHNEASPVSILEALACQTPVLSTDVGSVKESVRQGETGFLVPPGDAAAMAQHAVELLQTPQLADRLGKAGRELVVGTGSLEAMVDGYESLIQEQYDRQVHSPQASWMIWQPLAALGSRRARG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J184</accession>
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        <submittedName>
            <fullName evidence="5">Planctomycete cytochrome C</fullName>
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    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
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    </reference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
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            <end position="1059"/>
        </location>
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        <location>
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            <end position="90"/>
        </location>
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        <location>
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            <end position="1002"/>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="QDV59092.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1059" mass="118440" checksum="8BB41DB6D6061B2D" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
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            <fullName evidence="1">Uncharacterized protein</fullName>
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            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
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                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
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                <person name="Spormann A.M."/>
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                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="1 2">Mal33</strain>
        </source>
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        <source>
            <dbReference type="EMBL" id="QDV59170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="69" mass="7715" checksum="1DE7F2E1178CA0AC" modified="2019-10-16" version="1">MECLKSKPKMESTRLETARGFKAVPFRLNGRVSVIPNHAEYSVLQFSCLLGRTRTNVTIGALGRVFAIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
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    <name>A0A518J1H5_9BACT</name>
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        <name evidence="6" type="primary">ybhF_7</name>
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    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
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                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
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                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
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                <person name="Bruemmer F."/>
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                <person name="Spormann A.M."/>
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                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="6 7">Mal33</strain>
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        <source>
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        <source>
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        </source>
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    </evidence>
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    </evidence>
    <sequence length="316" mass="34822" checksum="CB4F1E5FEE70BF00" modified="2019-10-16" version="1">MNAGYDGPMIEVRDLCRSFGDTQAVDHVSFEVPRGSVFGYIGPNGAGKTTSMRILATLELPTSGDALVEGLSSVNDPDRVRGRLGFMPDSFGTYGDTNCIEYLDFFARSYGLVGRDRTRRLRWVMEFTGLRPLATKPMRGLSKGMRQRLCLGRALIHDPAVLVLDEPAAGLDPRARIELRQIIRALAADGKTILISSHILTELAEMCDRIGIIERGKLLATGSVDDIRRTLQPTRELLVRVASDDARALELLRSDSRATNVRVIDGAIRFSIAGDEADQVAILHALCDARIEILEYTPQHNSLEDVFLQVTKGQVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1H9</accession>
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    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
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                <person name="Bruemmer F."/>
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                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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            <end position="65"/>
        </location>
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</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
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                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
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                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
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                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
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                <person name="Bruemmer F."/>
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                <person name="Spormann A.M."/>
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                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
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                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8 9">Mal33</strain>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="project" value="InterPro"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="entry name" value="ARM-like"/>
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        <property type="entry name" value="Cyt_c-like_dom"/>
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        <property type="entry name" value="Cyt_c-like_dom_sf"/>
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        <property type="entry name" value="Quinoprot_gluc/sorb_DH"/>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021721978" evidence="6">
        <location>
            <begin position="30"/>
            <end position="1037"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="7">
        <location>
            <begin position="890"/>
            <end position="1026"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="310"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV59230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1037" mass="112685" checksum="15B679B28928DD77" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1M9</accession>
    <name>A0A518J1M9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Arylsulfatase</fullName>
            <ecNumber evidence="7">3.1.6.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Mal33_52750</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="PTM">
        <text evidence="3">The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the sulfatase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.6.1" evidence="7"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004065">
        <property type="term" value="F:arylsulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024607">
        <property type="entry name" value="Sulfatase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00523">
        <property type="entry name" value="SULFATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022219392" evidence="5">
        <location>
            <begin position="23"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase" evidence="6">
        <location>
            <begin position="27"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="477"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="482"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="modified residue" description="3-oxoalanine (Cys)" evidence="3">
        <location>
            <position position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR600917-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV59247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="499" mass="55545" checksum="686869812682650D" modified="2019-10-16" version="1" precursor="true">MIRSTVRCLLLALCFSPCIVNAADARPNVIVFIADDVSWNDFGCYGNPQARTPNIDRLAAGGLRLDQAYLTASSCSPSRASMITGRYPHNNGPASELHLPIAANLPWFPERLRDAGYYTALSGKNHMSIGKLEPGQSARPKAFDLVDRGRNKNNGGGHANWVRIAKDRPRDKPFFFWYAAYDAHRAWDGDSQWDAKKYGPRHTPESVRVPKFLVDDLPTRQDLASYYNEVTRFDYFIGEVVQELAEQKVLDNTLILVLADNGRPFPRAKTRLHDSGMKTALVAHWPATIKPGEVSNSLVSAIDIAPTVLSVAGAEIPETVQGVSMLPLFTDPSATIRRYAFSEHNWHDFEAHGRSIRDGRFLFIQNNRPQFPWQGPADSVNSPSHEQLRLQRDGNKLTAAQQDVFTAPRPAEELYLVDADPDQLNNLIDDKRYAADADRLRKLLDDWSVATGDTVPDQISSDSFDRETGDRLPIAKNAFRGTPAGTQRNATTVNNPGPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1T1</accession>
    <name>A0A518J1T1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_53220</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="71" mass="8227" checksum="13308D0C9FE0FC03" modified="2019-10-16" version="1">MRFRIVQASHFLRLCQRILQRQYARNALADVRHSAGSHGSDENKKTADPKPGRPLHYRSLEALSDYFFRAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1T3</accession>
    <name>A0A518J1T3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Calx-beta domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_53160</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031012">
        <property type="term" value="C:extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007154">
        <property type="term" value="P:cell communication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2030">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038081">
        <property type="entry name" value="CalX-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003644">
        <property type="entry name" value="Calx_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002105">
        <property type="entry name" value="Dockerin_1_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036439">
        <property type="entry name" value="Dockerin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013517">
        <property type="entry name" value="FG-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028994">
        <property type="entry name" value="Integrin_alpha_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001818">
        <property type="entry name" value="Pept_M10_metallopeptidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033764">
        <property type="entry name" value="Sdr_B"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03160">
        <property type="entry name" value="Calx-beta"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00404">
        <property type="entry name" value="Dockerin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13517">
        <property type="entry name" value="FG-GAP_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00413">
        <property type="entry name" value="Peptidase_M10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17210">
        <property type="entry name" value="SdrD_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00237">
        <property type="entry name" value="Calx_beta"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141072">
        <property type="entry name" value="SSF141072"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63446">
        <property type="entry name" value="SSF63446"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69318">
        <property type="entry name" value="SSF69318"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Calx-beta" evidence="4">
        <location>
            <begin position="1463"/>
            <end position="1562"/>
        </location>
    </feature>
    <feature type="domain" description="Calx-beta" evidence="4">
        <location>
            <begin position="1686"/>
            <end position="1784"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1922"/>
            <end position="1944"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV59288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1954" mass="203591" checksum="66EC3BD889D181A2" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J205</accession>
    <name>A0A518J205_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_53950</name>
    </gene>
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        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
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            <end position="147"/>
        </location>
    </feature>
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        <location>
            <begin position="128"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV59367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="147" mass="15788" checksum="1D9FD6839AEB4505" modified="2019-10-16" version="1" precursor="true">MRNLITTLRLALCSLPLLVGCGQQQFPGEQPVFPIEGVVTVDGKPVENIQIALHPAGDLNAEKPFYPQGFTDAEGNVKVSTYADGDGAPAGDYRVTFVLKEYNLLSRSFTGPNRLSAQYADSAKTPITLSVGPDQSNDLGKLDFESN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J213</accession>
    <name>A0A518J213_9BACT</name>
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        <submittedName>
            <fullName evidence="2">Xylose isomerase-like TIM barrel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_54100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="Pfam" id="PF01261">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="SSF51658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AP_endonuc_2" evidence="1">
        <location>
            <begin position="27"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="336" mass="36533" checksum="50246A308455D7D2" modified="2019-10-16" version="1">MPASAPSVLLSGFSDEAAIDKTAVQQFAAFAALGMKWFSLRFIDAGDGIKNAMQLTDPEIKTIRELMDAYGLRVATLGSPIGKVKLKDVDDGTSNRYVPFEEYLKTEVVRACELATAFDCKLIRGFSYYHPKGTKPEEHLSQACDQLGKIAEVCDSYGLTYGLEVEANLIGQTGQLMAQLHEGVNHPALVTIFDGANISTQGFSADQVYEQYLAMKPGLGWLHIKDYHDPSPTGRIHHVDEASLKNFVPADRGDCGHEAILRDLAAYMPEVEARMAKRGAPGVVCDLEPHVKGGGQFGGFSGPDGFGVAMRGLCRVLDYVGIDYETRSFDDIKASI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J230</accession>
    <name>A0A518J230_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Electron transport protein YccM</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">yccM_2</name>
        <name evidence="6" type="ORF">Mal33_54270</name>
    </gene>
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        <lineage>
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            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Rosistilla</taxon>
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    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014116">
        <property type="entry name" value="Cyt_c_oxidase_cbb3_FixG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032879">
        <property type="entry name" value="FixG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13746">
        <property type="entry name" value="Fer4_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12801">
        <property type="entry name" value="Fer4_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11614">
        <property type="entry name" value="FixG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02745">
        <property type="entry name" value="ccoG_rdxA_fixG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="56"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="101"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="167"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="207"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="345"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="5">
        <location>
            <begin position="267"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV59392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="478" mass="52712" checksum="C00AD95088AE7BFD" modified="2019-10-16" version="1">MNDKRSLPVLPHTAASGAAVTSHDDDDVLSTLRRDGSRRWLMPHLATGGWWRKRRVVAYILMVVFVAVPHLRVAGKPLILMDIPARQFTIFGRTFLPTDTMLLALLMLSVMFGIVLITAIAGRAWCGWACPQTVYMEYLFRPIDRLFDGTTGRGGHAKKPLTGVKQVARVAVYVLLSMFLAHTFLAYFVGTERLSQWIQSSPIDHPAAFLVMAATTGLMLFDFLIFREQMCLIACPYGRFQSVMLDEQSLIVTYDPVRGEPRKKGKHRAEDNAGDCVDCNRCVVVCPTGIDIRDGLQMECINCTQCIDACDDVMDRVGSPRGLIRYGSQDGIAGKPRRRFRPRTIIYPLILTAVLSGFAYALSTKTTFDARVLRGKGAPFTTVARGRISNSFTIRLVNRTDEKQTYALQVAEPANVQLKVIDPTGLTLEPGGTSLVPVATEFGGSLTFGTGNQPATLEVTSSKDASKTVQFNLLGPRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J232</accession>
    <name>A0A518J232_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FixH</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_54280</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008620">
        <property type="entry name" value="FixH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05751">
        <property type="entry name" value="FixH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="23"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="176" mass="19473" checksum="21ED4AD53EA50450" modified="2019-10-16" version="1">MINQQATVAQRTDQQIAERKAKWFWVSLVVALLGLQLVIGGVAIKLATGDASAAIVPNYHQAALNWDQIHSERTAAKRLGWTVDLDVSNVADGRGMRAVQVSIADADGKPIDDLQVSADIYHHARAAEVQTVDMQPVGDAEYQVLAPMERSGLWQVDLNIRHEDQRITVQRTLERD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J267</accession>
    <name>A0A518J267_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">D-xylose-proton symporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">xylE</name>
        <name evidence="8" type="ORF">Mal33_54650</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="41"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="99"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="132"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="166"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="249"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="282"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="312"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="375"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="404"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="7">
        <location>
            <begin position="8"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV59430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="445" mass="48728" checksum="F5A6708915CCF65C" modified="2019-10-16" version="1">MNPRLFIWSLTSALAGFLFGFDTIVISGAEQDIQTQWRLDGMTHGLCMSAALWGTVLGAVFGGLPTERFGRRKTLLWIGCLYFVSAVGSALAGEQYTFMLARFIGGVGVGIATVASPLYIAEISPPGLRGRLAGMFQFNIVFGILVAFVSNYLIGNYVDAAVAWRWMLGVEAIPALIYTVMCFTIPESPRWLITHGGQRDAGREIFATVNPDFSDQQLTELVDSVQAGGGEASTKTPFFTGRLQKPITLAFLIAFFNQLSGINAILYFAPRIFEWTGLGENAALLQSVGIGITNLIFTYLGLWLIDRLGRRTLMLIGSCGYIASLGLCTWAFWTETFRIVPACIFAFIAAHAIGQGAVIWVFISEIFPNRHRATGQALGSSTHWLFAALLTLVFPMLAAQLPPAAIFGFFAGMMVLQLFWVKFFMPETKGVPLEEMQSRLGIREA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J270</accession>
    <name>A0A518J270_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Macrolide export ATP-binding/permease protein MacB</fullName>
            <ecNumber evidence="12">3.6.3.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">macB_9</name>
        <name evidence="12" type="ORF">Mal33_54640</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="3.6.3.-" evidence="12"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0046">Antibiotic resistance</keyword>
    <keyword evidence="5 9 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="556"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="609"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="664"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="22"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="58"/>
            <end position="65"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QDV59429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="704" mass="77646" checksum="BAF8EF1F3FCB4C7B" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J2D5</accession>
    <name>A0A518J2D5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_55270</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="386" mass="41896" checksum="4C9DBC8A10D4E7E4" modified="2019-10-16" version="1">MSFDNLDLNGTSLMARLHGSPLPTAEEMGSPQQRRSTGRSIGLCAPIKCLAFAMLLGLPGIATAQFDQVYPLRGAPMNGEFVGSTPTEVTIKVQGTDRKIAVNEIRRLGFKEDPAELKQARSRVASGDYQAAMDELKKINPASVTRPIILLDLQFYLALCEGKLALSSGGDKGSAASAMLAFVRKASKSHHFFAAAEMLGDLAVALGKYPEAIKYYGAISAQAPWPEYKMHAVMLEARALMAQKDFANAEKKFASLANATASTAETKRQQLLAQVGVARCQAETQSPEAAIAAIQKLVADNDESDAELFGRAYNALGACYLKANKPKEALMAYLHVDVLFYAQPEIHAEALYQLSKLWEQVKKTDRANAARNLLNDRYAGSRWASM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J2D9</accession>
    <name>A0A518J2D9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Periplasmic serine endoprotease DegP</fullName>
            <ecNumber evidence="5">3.4.21.107</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">degP</name>
        <name evidence="5" type="ORF">Mal33_55360</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.4.21.107" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041489">
        <property type="entry name" value="PDZ_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001940">
        <property type="entry name" value="Peptidase_S1C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13180">
        <property type="entry name" value="PDZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17820">
        <property type="entry name" value="PDZ_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00834">
        <property type="entry name" value="PROTEASES2C"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 5" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022183576" evidence="3">
        <location>
            <begin position="20"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="4">
        <location>
            <begin position="274"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV59501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="498" mass="53178" checksum="2DB12884E9280C5E" modified="2019-10-16" version="1" precursor="true">MRQIAFLVVILLSTCPAPAQQPPDALLSMQSALTNAIDRAGRSVVAIARVRKDLPADAMGDLKFNLPGLGQPLIDPTNPAFVPTEFASGVIVSAAGDVLTNFHVLDDPKQNDYYVWHRGIGSQAVVQATPAEVQAGDPWTDLAILRIENAKDLPAIKMGDATQIRRGMFVISLGNPYAIARDGYPSASMGIVSNLQRAAAAQPDKESRGQAPASEQLHEFGTLIQTDAKLNLGTSGGALVNLQGEMIGLTTSLAAVAGYEQSAGFAIPIDKSMRAAIDQLREGKTPAFGFLGLEPADLPEPQRARGLRGAIVRQVLQGMPAQRAGLRSGDLITKIDGQPIDGAAGLFREMSRRPANAHVQMTLLQGNPLTDDFQSKIVDVTLGKKYLALTKPGYSRFPEPSWRGLRVDHGTALPPGQLFGFSRPREILPVAVISVDPDTPAWNAGLRPGQFVQKVGDKSVPDPDTFYELVKEQTDAVALTIVGPGDREQQISVPTSIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IM59</accession>
    <name>A0A518IM59_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FAD-dependent oxidoreductase LodB</fullName>
            <ecNumber evidence="2">1.-.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">lodB</name>
        <name evidence="2" type="ORF">Mal33_00990</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.-.-.-" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_3" evidence="1">
        <location>
            <begin position="5"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="414" mass="46339" checksum="BEB0D1EBC874DBEC" modified="2019-10-16" version="1">MKANYDVVVIGGGPAGSSAAALTAAAGHSTLLIEREAMPRFHIGESLMPEVYWPLQRLGVVDRMEELGFQKKLSVQFVTNSGKESSPFYFKQHDPRECSSTWQVERARFDQMLFERAAELGADCYDQTRLLDVEIDDQDRATGIRVRDAQGQEHTISSRVVVDATGLQSFIANKLGLKEINPDLKKAAIWGYWKNARRDEGENEGATIIMQTEKKDSWFWFIPLSNGITSIGCVGNNDYMLKQGLKPDAKYEQELSICPGLQERLKDAEFQGEIRVAKEFSYTTKRHAGEGWVLIGDAFGFIDPIYSSGVYFALETGVRAADAITEGFAKDDLSGAQLARWADDFKDGSSWIRKLVHAYYTNEFSFGRFMKAHPHHTGNLTDLLIGRIFHDQAGAIFDDMDEAIEAAKRDAMSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IM78</accession>
    <name>A0A518IM78_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_01230</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="181"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="566" mass="65149" checksum="50CEDE88F8706564" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMB4</accession>
    <name>A0A518IMB4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">CRISPR-associated endonuclease Cas1</fullName>
            <ecNumber evidence="11">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">cas4-cas1</name>
        <name evidence="11" type="synonym">cas1</name>
        <name evidence="14" type="ORF">Mal33_01880</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="11">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="11">Homodimer, forms a heterotetramer with a Cas2 homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the CRISPR-associated endonuclease Cas1 family.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="11"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051607">
        <property type="term" value="P:defense response to virus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043571">
        <property type="term" value="P:maintenance of CRISPR repeat elements"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.100.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01470">
        <property type="entry name" value="Cas1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002729">
        <property type="entry name" value="CRISPR-assoc_Cas1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042206">
        <property type="entry name" value="CRISPR-assoc_Cas1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042211">
        <property type="entry name" value="CRISPR-assoc_Cas1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013343">
        <property type="entry name" value="CRISPR-assoc_prot_Cas4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022765">
        <property type="entry name" value="Dna2/Cas4_DUF83"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011604">
        <property type="entry name" value="PDDEXK-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01867">
        <property type="entry name" value="Cas_Cas1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01930">
        <property type="entry name" value="Cas_Cas4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00287">
        <property type="entry name" value="cas1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00372">
        <property type="entry name" value="cas4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0051">Antiviral defense</keyword>
    <keyword evidence="9 11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 11 14" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="4 11 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5 11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10 11" id="KW-0464">Manganese</keyword>
    <keyword evidence="2 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 11" id="KW-0540">Nuclease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cas_Cas4" evidence="13">
        <location>
            <begin position="20"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="70"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="408"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="490"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="505"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="QDV54238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="598" mass="67012" checksum="2C0DC871B5201846" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IME8</accession>
    <name>A0A518IME8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_02220</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="102" mass="11887" checksum="D16397B113DD791C" modified="2019-10-16" version="1">MIHYTCDRCNCELTPNEDLRYSVQVEIKAVFDTPTDFVEDVDTDHLLELDEILERLGDDESDAIGEDVYQRRRYDLCSGCFRQYQKNPLGREHSLSFGFSAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMH1</accession>
    <name>A0A518IMH1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_02380</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="70" mass="7289" checksum="1EBA18B5F17AEA71" modified="2019-10-16" version="1">MKWKTLEAANGALNLSSLPGLTYQVCPIFPAARAAGFMRPPHPRLRGGLSTAKSPQASTPLAGLAPFDLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMR0</accession>
    <name>A0A518IMR0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_03170</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="120"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="141"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="164"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="194" mass="21054" checksum="F973E8CCBCDD8DC1" modified="2019-10-16" version="1">MNTSTEAVSSADKVDSKAHSKSGGAWTTRLGILCAMLVLAIAGIGFTQATDTGAWEYWLFVVLVYAALGLWKSVRSAKQAGQSIHKTIIRELSHWGILVGFLAALLMLERREIINRDSASYFAVMLLALTCCLAGVHIDWLLLVVGISLTLMVLAMAMLEQLSAWIIMILVACVAVAIFYFKSKRDSSAAKGNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMT8</accession>
    <name>A0A518IMT8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_03480</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="30" mass="3109" checksum="5B4D13A81D400EBC" modified="2019-10-16" version="1">MTMLGLLAIGLVTFVIIAAAVLMVYGGNKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IN69</accession>
    <name>A0A518IN69_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Leucyl/phenylalanyl-tRNA--protein transferase</fullName>
            <ecNumber evidence="4">2.3.2.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">L/F-transferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Leucyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Phenyalanyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4 6" type="primary">aat</name>
        <name evidence="6" type="ORF">Mal33_04910</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>L-leucyl-tRNA(Leu) + N-terminal L-arginyl-[protein] = H(+) + N-terminal L-leucyl-L-arginyl-[protein] + tRNA(Leu)</text>
            <dbReference type="Rhea" id="RHEA:50416"/>
            <dbReference type="Rhea" id="RHEA-COMP:9613"/>
            <dbReference type="Rhea" id="RHEA-COMP:9622"/>
            <dbReference type="Rhea" id="RHEA-COMP:12672"/>
            <dbReference type="Rhea" id="RHEA-COMP:12673"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:64719"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78494"/>
            <dbReference type="ChEBI" id="CHEBI:133044"/>
            <dbReference type="EC" id="2.3.2.6"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>L-leucyl-tRNA(Leu) + N-terminal L-lysyl-[protein] = H(+) + N-terminal L-leucyl-L-lysyl-[protein] + tRNA(Leu)</text>
            <dbReference type="Rhea" id="RHEA:12340"/>
            <dbReference type="Rhea" id="RHEA-COMP:9613"/>
            <dbReference type="Rhea" id="RHEA-COMP:9622"/>
            <dbReference type="Rhea" id="RHEA-COMP:12670"/>
            <dbReference type="Rhea" id="RHEA-COMP:12671"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:65249"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78494"/>
            <dbReference type="ChEBI" id="CHEBI:133043"/>
            <dbReference type="EC" id="2.3.2.6"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>an N-terminal L-alpha-aminoacyl-[protein] + L-phenylalanyl-tRNA(Phe) = an N-terminal L-phenylalanyl-L-alpha-aminoacyl-[protein] + tRNA(Phe)</text>
            <dbReference type="Rhea" id="RHEA:43632"/>
            <dbReference type="Rhea" id="RHEA-COMP:9668"/>
            <dbReference type="Rhea" id="RHEA-COMP:9699"/>
            <dbReference type="Rhea" id="RHEA-COMP:10636"/>
            <dbReference type="Rhea" id="RHEA-COMP:10637"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78531"/>
            <dbReference type="ChEBI" id="CHEBI:78597"/>
            <dbReference type="ChEBI" id="CHEBI:83561"/>
            <dbReference type="EC" id="2.3.2.6"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the L/F-transferase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.6" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008914">
        <property type="term" value="F:leucyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030163">
        <property type="term" value="P:protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00688">
        <property type="entry name" value="Leu_Phe_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004616">
        <property type="entry name" value="Leu/Phe-tRNA_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042203">
        <property type="entry name" value="Leu/Phe-tRNA_Trfase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30098">
        <property type="entry name" value="PTHR30098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03588">
        <property type="entry name" value="Leu_Phe_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00667">
        <property type="entry name" value="aat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4 6" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="188"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV54536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="207" mass="23145" checksum="9140B6DFBF1C3931" modified="2019-10-16" version="1">MLDAYRHGIFPWPCRWADQWFVGWHSPDPRAILPLDDVRIPKRLQRKLRAGHFRFRWNSCFDSVLQHCASVGVRKENAWLCPDLLDAISSLHRSGDAHCIEVYDRDGTLCGGLYGIAVGAAFSAESMFHLQSDASKAAVCGLVAVLRHAGFELMDIQQTSPHLLAFGAVEIDRCDYLVALQRALGKQPSWPATTEHPIPIDRIGAED</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP04</accession>
    <name>A0A518IP04_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Efflux pump membrane transporter BepE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">bepE_1</name>
        <name evidence="3" type="ORF">Mal33_07910</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2090.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82714">
        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="380"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="408"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="451"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="487"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="522"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="552"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="928"/>
            <end position="947"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="953"/>
            <end position="973"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="980"/>
            <end position="1004"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1024"/>
            <end position="1045"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1057"/>
            <end position="1083"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="630"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="633"/>
            <end position="649"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1096" mass="118188" checksum="DCA01C55C4600B8B" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP70</accession>
    <name>A0A518IP70_9BACT</name>
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        <submittedName>
            <fullName evidence="5">Sporulation kinase A</fullName>
            <ecNumber evidence="5">2.7.13.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">kinA_1</name>
        <name evidence="5" type="ORF">Mal33_08560</name>
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        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.13.3" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
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    </dbReference>
    <dbReference type="SMART" id="SM00388">
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="37"/>
            <end position="59"/>
        </location>
    </feature>
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        <location>
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            <end position="111"/>
        </location>
    </feature>
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        <location>
            <begin position="201"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV54891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="411" mass="44901" checksum="C6A70F5786B397AF" modified="2019-10-16" version="1">MRILAIVLVLVFITEVAVMFALPYIVPGSLNEAGRAIVDAVLLTMVCAPAMWLVIIGPLRRIAVQEHQRSETIVANASESILTFDREGSILSCNRAATELIAIDAEALIGQFMQQVIPGLPDRFSGLPNEFRLDAVRADGHRFPVQVSVSEYPSESQAMRIAIIRDLTESQKAEQQRLTMARETEALRAQQMATLAQLATGVAHEIRNPLTSIKMLIQVNRAKCADEGLPTDDMELVEREIRRMERSVNSLLDYARPERGESTEFAIQDAVRRTVMLIDGRCKTQNVRLQVTAPDPPLLVLGDTAQIQQLLLNLMLNAIDAMPEGGTLELAVVREDKDVILTVSDSGSGISESVLDRLFSPFVSTKPNGVGLGLGICRRIAESHRGSLVGSNRASGGAQFRLSLPLVQSST</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPF0</accession>
    <name>A0A518IPF0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CobQ/CobB/MinD/ParA nucleotide binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_09240</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002586">
        <property type="entry name" value="CobQ/CobB/MinD/ParA_Nub-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01656">
        <property type="entry name" value="CbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CbiA" evidence="2">
        <location>
            <begin position="310"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="489" mass="52277" checksum="35128952D6678DD3" modified="2019-10-16" version="1">MPTQTNRPMPVSSPTFPADEPVLEYQVMTTSIDQAFRKAYAKRTGTSGSTSESANGTIAVWIDEPSGQFFRNEPAHAVGAPHFQQAPATELPVAESETPAAEADKLANAASELATPPQPAAQQTPAAQAPETPAAPQAHAEQPIAAVASPLVSDAIDLEPKAEPMTYADPLVSVEVSATNPQPVVRPIDIADDEPTVVVPAPVVPAPVVAKPAIEPQIDIRPGTTAYDAWSAKLETLELPKKAEAPLSSEPTISKQAATINRESLPAFAPVWEVDEFVLPEVAKNLATDHLLPMGAQLERASREGLQTMAVSSQNRDTGRSTVAIAIAQVAATAGLRVALVDADTENPSLLEKLQLEMSNDWVDAIAQDVSIEEVAVLSLSNNFCFLPLLKKSPEQLKQVDRCAASLLERLKLHFDLIVVDFGPLHHASFGLSIPLSDEFFDAVVLIEDMRRIDPETLETYARRIRAVGIENIGLIENYTDADASDAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPP4</accession>
    <name>A0A518IPP4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_10300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="73" mass="7943" checksum="0CD6B01A3D59F6EE" modified="2019-10-16" version="1">MQQVKIFKSIESELDQLEVEINRWIARLHKKGGKVVKLEGNIAPKSGGGGTGPMSSFSASDVMVIILFEIDIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPT6</accession>
    <name>A0A518IPT6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">4-hydroxy-3-methylbut-2-enyl diphosphate reductase</fullName>
            <shortName evidence="5">HMBPP reductase</shortName>
            <ecNumber evidence="5">1.17.7.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 6" type="primary">ispH</name>
        <name evidence="6" type="ORF">Mal33_10800</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>H2O + isopentenyl diphosphate + 2 oxidized [2Fe-2S]-[ferredoxin] = (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:24488"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:128753"/>
            <dbReference type="ChEBI" id="CHEBI:128769"/>
            <dbReference type="EC" id="1.17.7.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>dimethylallyl diphosphate + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] = (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:24825"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57623"/>
            <dbReference type="ChEBI" id="CHEBI:128753"/>
            <dbReference type="EC" id="1.17.7.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="5">Binds 1 [4Fe-4S] cluster per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Isoprenoid biosynthesis; dimethylallyl diphosphate biosynthesis; dimethylallyl diphosphate from (2E)-4-hydroxy-3-methylbutenyl diphosphate: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 6/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the IspH family.</text>
    </comment>
    <dbReference type="EC" id="1.17.7.4" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00056">
        <property type="reaction ID" value="UER00097"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00059">
        <property type="reaction ID" value="UER00105"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051745">
        <property type="term" value="F:4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050992">
        <property type="term" value="P:dimethylallyl diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019288">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd13944">
        <property type="entry name" value="lytB_ispH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00191">
        <property type="entry name" value="IspH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003451">
        <property type="entry name" value="LytB/IspH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30426">
        <property type="entry name" value="PTHR30426"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02401">
        <property type="entry name" value="LYTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00216">
        <property type="entry name" value="ispH_lytB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="3 5" id="KW-0408">Iron</keyword>
    <keyword evidence="4 5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="222"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="126"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="12"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="74"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="266"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV55111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="310" mass="34086" checksum="B2972A99322D5D24" modified="2019-10-16" version="1">MKIHLAAPRGFCAGVNMAVESLEIALEAMGPPVYVYHEIVHNQYVVRTFRSKGAVFVNELIDVPEGATVLFSAHGVAPATRELAKQRKLTAIDATCPLVTKVHLEAIRYAKQGYTIFLIGHDGHDEVIGTMGEAPEAIILVETEEDVDKLDVADEAKLAYLTQTTLSVDDATRIINRLKARFPELKGPPKDDICYATQNRQEAVRLLSDAADAVIVLGSQNSSNSQRLRELAESPDRPAFLIDGPEDLSVDQFQADWTVLVTAGASAPESVVNATIQWLEEHFDATVELKTVREEKVSFPLPKPLRQYAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQ34</accession>
    <name>A0A518IQ34_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">dTDP-glucose 4,6-dehydratase</fullName>
            <ecNumber evidence="2">4.2.1.46</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rfbB_2</name>
        <name evidence="2" type="ORF">Mal33_11790</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="4.2.1.46" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008460">
        <property type="term" value="F:dTDP-glucose 4,6-dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="4"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="315" mass="34061" checksum="339DA38FFB1D800C" modified="2019-10-16" version="1">MKRVLVTGANGFVGRYACKYLQAAGWQVRGTIRNQDSTGLPESVEPLVIGDIAAFDHWEKALKGVDAVVHLVARTHVIHEKSTDPLPLYRKVNVDGTQRLIDGCRGASVKRFLFVSSIKAVGESSTTSLTETDVCEPEDAYGVSKLEAEQIVASAAALSMETVILRPPLIYGPGVLGNFQRILKAVDRGLPLPLRGTTNQRSLLYVENFAAAIAVCLEHPAAANQTFHLADSEPVSSGDLVRQISLALGCKPRLVPFPVPLLRMLGTIARKQDQVSRLVDSLTVSTSKIEHATGWQPEFTLCQGLAATAQHYRAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQT1</accession>
    <name>A0A518IQT1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Arabinose 5-phosphate isomerase KdsD</fullName>
            <ecNumber evidence="8">5.3.1.13</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">kdsD</name>
        <name evidence="8" type="ORF">Mal33_14220</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the SIS family. GutQ/KpsF subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.13" evidence="8"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019146">
        <property type="term" value="F:arabinose-5-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901135">
        <property type="term" value="P:carbohydrate derivative metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05014">
        <property type="entry name" value="SIS_Kpsf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004800">
        <property type="entry name" value="KdsD/KpsF-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001347">
        <property type="entry name" value="SIS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035474">
        <property type="entry name" value="SIS_Kpsf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01380">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004692">
        <property type="entry name" value="KdsD_KpsF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00393">
        <property type="entry name" value="kpsF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51464">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0129">CBS domain</keyword>
    <keyword evidence="8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="SIS" evidence="7">
        <location>
            <begin position="55"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="6">
        <location>
            <begin position="223"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="6">
        <location>
            <begin position="293"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="site" description="Catalytically relevant" evidence="4">
        <location>
            <position position="73"/>
        </location>
    </feature>
    <feature type="site" description="Catalytically relevant" evidence="4">
        <location>
            <position position="125"/>
        </location>
    </feature>
    <feature type="site" description="Catalytically relevant" evidence="4">
        <location>
            <position position="166"/>
        </location>
    </feature>
    <feature type="site" description="Catalytically relevant" evidence="4">
        <location>
            <position position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR004692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR004692-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR004692-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV55448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="360" mass="37983" checksum="D59FFC42116B2F41" modified="2019-10-16" version="1">MSAQPIPKPAGDCANDSLAAATPIEQLRFARNVIRVEGQHLTRLAAEIDQRIVAAANQLLACKGSVIISGIGKAGIIGQKLSATLSSTGTRSHFLHSAEAVHGDLGKVQADDVVVLLSHSGKTEEVVRLLPALSAQSQSLIAITASANSPLGQGVDLVIEIGSTQEVCTLGLAPSTSTTAMLAVCDALALLTSELRGFTSSDFARYHPGGSLGQKLSSVDDVMRPVGQCRIASDSTSVRDVLVMNSKSGRRSGAVMLTDQEGRLSGIFTDSDLARLLERRRERALDGPIVEVMSSQVTRVRSGSLLADAIQILAQRRISELPVTDANQRPVGLIDITDIVSLLPNDEPNPPQILPMRPQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQX3</accession>
    <name>A0A518IQX3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_14650</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="64" mass="6875" checksum="71C2E7C520090AF0" modified="2019-10-16" version="1">MLENARGDAHAVKLVVRDYAHAGELIVRGDAHAVKLVVRGYAYAGELVVRGDAHAGELELHAGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IR37</accession>
    <name>A0A518IR37_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein-L-isoaspartate O-methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_15260</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008171">
        <property type="term" value="F:O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001077">
        <property type="entry name" value="O_MeTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00891">
        <property type="entry name" value="Methyltransf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_2" evidence="1">
        <location>
            <begin position="140"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="326" mass="35236" checksum="AD2A9DDED3BD02AE" modified="2019-10-16" version="1">MANQQELTIRKYWTLIGINSTAHAIRAAREVGLFQQLLSGQKTFGELVDACDIQPNLTTRILDVLVASGLIEQYAEHYAASQTLGLLAQYDSDLGDYYLDSMVGQLRCDLPAGNGDAYRRHQVARGWTRTPLAMQAAAVLEIGQKRRDLRILEIGCGSGVWTSTLAFRDPGTTIVAIDHADALGEAKTMIESIDLQNRWKGIEGDPTSGELPEGPFDLVVIPELLQTIDDALAVTILGRAADVTRPDGEVAVIDFFDPIDAKERSLATAVQNLELGLRTPLGRLRTAPEASQLMVGAGLTSALYAPLTNAPQNAGLLMGTRPETLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IR43</accession>
    <name>A0A518IR43_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_15440</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010869">
        <property type="entry name" value="DUF1501"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07394">
        <property type="entry name" value="DUF1501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="473" mass="51914" checksum="D054C76B4EBC4277" modified="2019-10-16" version="1">MSCNNIIHPNSRRKFLQTAGSGFGALAFSALSGEALLPQRSVSAAAAKIPHFLGRAKSVIWLFMEGGPSHLDLFDPKPLLNELAGQSLPESFDKPVTAMGEVNSPLLESKRKWAQHGESGLWISDWLPKHSEIADDLCVIRSCVSDGINHAGGVSQMNTGSVFGGRPSLGAWVSYGLGTENQDLPGFVVIKDTKSMVVNGVRAWGAGFMPASYQGVLFESGEQPIANLNRPAGISEARQLQKLAFLNQLNQQHYASRESNTDLEARIRSYELAYRMQSSAPDAIELDDEPQETLELYGMDRKETKTFGRQCLMARRLAERGVRFIQLYHGAGSKWDSHSRMEANHSRLCDAVDQPIVGLIKDLKQRGLLDETLVVWGGEFGRTPMSEKGDGRDHNPTGFTMWMAGGGVRGGQTIGATDELGLFAIEDKLHVHDIHATIMRLMGLDHTKVVYMHKGRPERVDQNEGQAHKGIVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRB3</accession>
    <name>A0A518IRB3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Sporulation kinase E</fullName>
            <ecNumber evidence="7">2.7.13.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">kinE_1</name>
        <name evidence="7" type="ORF">Mal33_15600</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.13.3" evidence="7"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
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    </dbReference>
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        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
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        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
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            <end position="160"/>
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        <location>
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            <begin position="327"/>
            <end position="584"/>
        </location>
    </feature>
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        <location>
            <position position="91"/>
        </location>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV55583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="603" mass="65723" checksum="EB7043F5A0367D12" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRB6</accession>
    <name>A0A518IRB6_9BACT</name>
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        <recommendedName>
            <fullName evidence="3">NfeD domain-containing protein</fullName>
        </recommendedName>
    </protein>
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        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
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            <taxon>Planctomycetes</taxon>
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
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                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
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            <topology evidence="1">Multi-pass membrane protein</topology>
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            <end position="553"/>
        </location>
    </feature>
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            <end position="578"/>
        </location>
    </feature>
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        </location>
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    <feature type="transmembrane region" description="Helical" evidence="2">
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        </location>
    </feature>
    <feature type="domain" description="NfeD" evidence="3">
        <location>
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            <end position="727"/>
        </location>
    </feature>
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        <source>
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    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF01957"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="QDV55637.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="735" mass="79577" checksum="0AF93C92DB63281D" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
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        </recommendedName>
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    </gene>
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        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
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                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
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    </dbReference>
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        <location>
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            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="357" mass="40806" checksum="DAD7343ECB5504DB" modified="2019-10-16" version="1">MTMARKYLVDPAVTRWYHCISRCVRQAFLFHDKDNLDRRDWRQWIEDRLELLDSNFAISVGGFSVMDSHLHVLCRLDPEVADRWNPQEVMRRWIAIYPPKTLKSNDKKVVRQWVETQAKDHRRVTLLRDRLKNLGWFMKSLKEPLARLANKADACHGTFWEARYKSIAILDNDALLSTSTYIDLNPLAAGIASTPEEGLHTSIHQRVEHVCQKGEKEIERLQAARRGSVAASVAAGVMEQDLWLVPIEDRRGIVQEERSGASCREGMLESFPLGSYLLLLDYTGRLFRDGKANMESGVKEIFDRLSSTLQSCQARTDKMLRSKSLRGSFFASDNQTVAAIATAPGHHFRNLSPQPPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRP0</accession>
    <name>A0A518IRP0_9BACT</name>
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        <submittedName>
            <fullName evidence="3">Internalin-A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">inlA_1</name>
        <name evidence="3" type="ORF">Mal33_17450</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
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                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
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    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021815263" evidence="2">
        <location>
            <begin position="25"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="377" mass="40547" checksum="C736FA75F64A1A02" modified="2019-10-16" version="1" precursor="true">MHRLYITPAFLLILALTGCNTKPAADPAGAEPDAAASAAADAKPAPSVSDDAEAVAAIMNVTEKVRRDGDGLIIEVDYRGTSVSDADLAPLTKLPRLRSVLLLGTPITGEALTTLAQIESLENLDLRDTAVDDASLEHLVGHKRLKALRLSGKSGDCSVGDDGMAHVAQIPNLKVLALDFLWVSEDGLDALAPLQQLQEIYLAETTIGNEAIAKLAQFPQLKKVRLARNQIDASGLADMPKLTNLEELDLSECSQILDDAMPPLGQLTKLKKLNLWRVNLTDAGIEPLNTLVNMEWLNLDNTRLTDAGMPYLSGMSKLLFLHLGSTLITDAGLEPLKNLKSLEDLKVTRTAVTQEGVDALKPSLPNTDIQLRYLGDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRX9</accession>
    <name>A0A518IRX9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cytochrome c oxidase subunit 3</fullName>
            <ecNumber evidence="9">1.9.3.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ctaE_1</name>
        <name evidence="9" type="ORF">Mal33_18190</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the cytochrome c oxidase subunit 3 family.</text>
    </comment>
    <dbReference type="EC" id="1.9.3.1" evidence="9"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004129">
        <property type="term" value="F:cytochrome-c oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019646">
        <property type="term" value="P:aerobic electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024791">
        <property type="entry name" value="Cyt_c/ubiquinol_Oxase_su3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000298">
        <property type="entry name" value="Cyt_c_oxidase-like_su3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035973">
        <property type="entry name" value="Cyt_c_oxidase_su3-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013833">
        <property type="entry name" value="Cyt_c_oxidase_su3_a-hlx"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11403">
        <property type="entry name" value="PTHR11403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00510">
        <property type="entry name" value="COX3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81452">
        <property type="entry name" value="SSF81452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50253">
        <property type="entry name" value="COX3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="18"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="53"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="86"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="123"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="171"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="COX3" evidence="8">
        <location>
            <begin position="1"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV55840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="195" mass="21408" checksum="040A7C5014A21D78" modified="2019-10-16" version="1">MVASTALPADKRAQQGGLLFLASLLVFFITGIISFVLYASWREATFIQSEKLPLSFAWSTLCLVFVSGLLHWAVHCVRHEHCRQSLALLVAALIGSIIFLVVQGVAMWHVAGGYATAGLEAGLAGMMLVLALLHALHVIGGVAALVIVTIRLARGQYDHERMWGISFTAQYWHFLDLVWIVMLFAFWYTSGGFAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IS08</accession>
    <name>A0A518IS08_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Recombination protein F</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_18120</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022602">
        <property type="entry name" value="DUF2813"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13304">
        <property type="entry name" value="AAA_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11398">
        <property type="entry name" value="DUF2813"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATPase_AAA_core" evidence="1">
        <location>
            <begin position="243"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="398" mass="44656" checksum="B00603ECAEE6FF55" modified="2019-10-16" version="1">MNVDMNTLPFETITIDGFRGLRDLRLEGLGAVNILVGDNNSGKTSVLEAMSIACNPFGPQEWLAMIRRRDFGGLDENRGQSLRWCFPQSGALRNQDFMFKGRCEINSQGRYPLRKLVAEVSDIQGIPSLNELKRMRRLPEDATESIAFAESWRGIELKHVVEMNDAADQPTPFGFPTVSTTDPITLQFWDDDDRMGPILSRPRQGNLPSSTLTPYSYQINQLQLRSHSSQLFQGNGDAMEKREHVLDLIRQFDPEITDIQIASYGGFDAAIYLNHKRLGPAPLSVFGDALRRAVLLSSTLPKLEGGLLLIDEIETGIHISSLVKVFDWLMKTAKQFDVQVIATTHSLEAIDGILAASGDNLDDLVTFHLDNDGDRTDAKRIYGDLLRRMRHQRGLDVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISJ0</accession>
    <name>A0A518ISJ0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cytochrome c551 peroxidase</fullName>
            <ecNumber evidence="10">1.11.1.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ccp_2</name>
        <name evidence="10" type="ORF">Mal33_20330</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
        <text evidence="6">Binds 2 heme groups.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="6">Binds 2 heme groups per subunit.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.5" evidence="10"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004130">
        <property type="term" value="F:cytochrome-c peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004852">
        <property type="entry name" value="Di-haem_cyt_c_peroxidsae"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026259">
        <property type="entry name" value="MauG/Cytc_peroxidase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03150">
        <property type="entry name" value="CCP_MauG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00034">
        <property type="entry name" value="Cytochrom_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000294">
        <property type="entry name" value="Cytochrome-c_peroxidase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 6 8" id="KW-0349">Heme</keyword>
    <keyword evidence="5 7 8" id="KW-0408">Iron</keyword>
    <keyword evidence="3 7 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-0574">Periplasm</keyword>
    <keyword evidence="10" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome c" evidence="9">
        <location>
            <begin position="91"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="9">
        <location>
            <begin position="277"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="binding site" description="covalent" evidence="6">
        <location>
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        </location>
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            <dbReference type="ChEBI" id="CHEBI:30413"/>
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            <position position="116"/>
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        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
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        </ligand>
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            <position position="117"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
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        <location>
            <position position="292"/>
        </location>
        <ligand>
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        <location>
            <position position="295"/>
        </location>
        <ligand>
            <name>heme</name>
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            <label>2</label>
        </ligand>
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            <position position="296"/>
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        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>2</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="QDV56054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="414" mass="45228" checksum="695E7B6ECFBB791E" modified="2019-10-16" version="1">MRPVTRFFIVTLLLHSGLVLQAEQPKSARVNLGEDGLLTGIPGEGPLKEAEIKAWLAKPENHVTLEVSLPKGLDASTANLAIPEDNPLTRAKIELGRQLYFDARLSSDQTISCASCHSPSEGYGAKTQFGVGVGGQTGNRNSPISYNRILSKAQFWDGRAASLEEQAVGPIANPIEMGNTHDACIECVGAIPGYAMQFKAIFDDGVTIDNVGKALASFERAIVTGPAPYDYWNPLAKFKEVFALDLEDMDALRSEDPDLAKQYDDMVAAAQKHPMSESAQRGMTLFFGKANCALCHAGGNFADEQYHNLGVGMEVDDPDLGRYVVTKEEKDKGAFKTPTLRNVALSEPYMHDGSQKTLEEVVAWYNKGGHKNPWLSDKVKPLNLTEQEEKDVVAFMKEGLTGPFPKVEENRLPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISJ7</accession>
    <name>A0A518ISJ7_9BACT</name>
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        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_20410</name>
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        <dbReference type="NCBI Taxonomy" id="2527990"/>
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
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                <person name="Lage O.M."/>
                <person name="Pohl T."/>
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                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
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                <person name="Spormann A.M."/>
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                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 4">Mal33</strain>
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    </reference>
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        <property type="project" value="UniProtKB-KW"/>
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            <begin position="12"/>
            <end position="35"/>
        </location>
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    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1086"/>
            <end position="1113"/>
        </location>
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            <begin position="1090"/>
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        </location>
    </feature>
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        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="QDV56062.1"/>
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        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
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    <name>A0A518ISL1_9BACT</name>
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
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                <person name="Kaster A.-K."/>
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                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">Mal33</strain>
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            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
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            <dbReference type="Pfam" id="PF13454"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="QDV56086.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="575" mass="63774" checksum="0CAD9E5385F3ED20" modified="2019-10-16" version="1"> </sequence>
</entry>
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    <accession>A0A518ISP7</accession>
    <name>A0A518ISP7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
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                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
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                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
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                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
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                <person name="Spormann A.M."/>
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                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="1 2">Mal33</strain>
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    </reference>
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        <property type="entry name" value="PRibTrfase_dom"/>
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    <proteinExistence type="predicted"/>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56114.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="113" mass="11986" checksum="17A2DDB6F913D43F" modified="2019-10-16" version="1">MSKALLLSTDLFFASRIKSAAVEAGYEMSMGKSIEKVTLKEGLQVVIVDLSTTGSTVEAIAQHVREQAPSARLVAFGPHVQTGRLAAAREAGFDVVLTRGQLDHGLGQLFSEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IST2</accession>
    <name>A0A518IST2_9BACT</name>
    <protein>
        <submittedName>
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    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
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                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
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                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010297">
        <property type="entry name" value="DUF900_hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05990">
        <property type="entry name" value="DUF900"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021826268" evidence="3">
        <location>
            <begin position="35"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="188"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="215"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV56152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="556" mass="60095" checksum="A2EA48426622F7F2" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISW6</accession>
    <name>A0A518ISW6_9BACT</name>
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        <submittedName>
            <fullName evidence="8">Putative periplasmic serine endoprotease DegP-like</fullName>
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        <name evidence="8" type="primary">mucD_4</name>
        <name evidence="8" type="ORF">Mal33_21590</name>
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            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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        </lineage>
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.4.21.107" evidence="8"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="PDZ"/>
    </dbReference>
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        <property type="entry name" value="PDZ_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011782">
        <property type="entry name" value="Pept_S1C_Do"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001940">
        <property type="entry name" value="Peptidase_S1C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13180">
        <property type="entry name" value="PDZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17820">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00834">
        <property type="entry name" value="PROTEASES2C"/>
    </dbReference>
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        <property type="entry name" value="PDZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="degP_htrA_DO"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PDZ"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <location>
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            <end position="27"/>
        </location>
    </feature>
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            <end position="505"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="7">
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            <begin position="303"/>
            <end position="370"/>
        </location>
    </feature>
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            <begin position="396"/>
            <end position="494"/>
        </location>
    </feature>
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            <position position="143"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
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    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR611782-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV56178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="505" mass="52955" checksum="6D40D7FBD860DF55" modified="2019-10-16" version="1" precursor="true">MSITKFRKHKAPWITGFAIAAMIGSTAAVHLQAESNPPRGTAAVANANSLSEAFRETARVVAPSVVTITSETEVASPAPRQGQPMNDEMMKRFFGEGSPFGEMFRGQPQMQPFHKPSAESNTRTGIGSGVIIDASGLILTNNHVVADATNVMVKLADGREFQASEVKTDPKTDLAVLKIDGASDLVAARLGNSDRIEIGDWVLALGQPFGLEGTVTAGIISAKSRGIGITARENFLQTDAAINPGNSGGPLVNLAGEVIGINTAISSRSGGNNGVGFAIPIDEAKWVSDQLIKDGVVRRAMLGVGIQKVSHELASSFGVESNHGVLVTEVVKGSPADKAGLKSGDVILTFSGREVHDPRGLQNVVEQCAVGSKQKIEIMRDGSKMTIEAVCEVQPEAGLANKASESAASKIESLGMEVGNLTEDLARKLGVKDVAGVVITNVEPGSVADRAGLKAGNVITQVERKSVDSVDQFQAMTKDHDLSDAMLLLVKTDQGSRYVILKSGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IT10</accession>
    <name>A0A518IT10_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_22070</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="175" mass="20130" checksum="35B963FBB7E1BD2C" modified="2019-10-16" version="1">MRTSKTGVFLRSCFVIFCVFFPLSWLWNATTGTNFWKPWEMAISASLTVAFFGSLAWLITNVGMALLFGGKPEYRAYRSRGGDPFFDSLPRLFNPGCVKGADEPQTNFVPPAIWQFRCPRCNAGVQHRIDVCWNCLYGADSDSTAYFERYGDVKPPEITDEDWDDLRRRHDVWSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IT53</accession>
    <name>A0A518IT53_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative nucleotide-binding protein containing TIR-like domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_22430</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Pirellulaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="5"/>
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        </location>
    </feature>
    <feature type="domain" description="TIR-like" evidence="2">
        <location>
            <begin position="508"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="576"/>
            <end position="597"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF10137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF18864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV56261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="677" mass="75536" checksum="6B90DCE4B57F52A7" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITH3</accession>
    <name>A0A518ITH3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cysteine desulfurase</fullName>
            <ecNumber evidence="4">2.8.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">iscS_3</name>
        <name evidence="10" type="ORF">Mal33_23740</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[sulfur carrier]-H + L-cysteine = [sulfur carrier]-SH + L-alanine</text>
            <dbReference type="Rhea" id="RHEA:43892"/>
            <dbReference type="Rhea" id="RHEA-COMP:14737"/>
            <dbReference type="Rhea" id="RHEA-COMP:14739"/>
            <dbReference type="ChEBI" id="CHEBI:29917"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:64428"/>
            <dbReference type="EC" id="2.8.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.7" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031071">
        <property type="term" value="F:cysteine desulfurase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044571">
        <property type="term" value="P:[2Fe-2S] cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010240">
        <property type="entry name" value="Cys_deSase_IscS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016454">
        <property type="entry name" value="Cysteine_dSase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11601:SF34">
        <property type="entry name" value="PTHR11601:SF34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005572">
        <property type="entry name" value="NifS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_5" evidence="9">
        <location>
            <begin position="55"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV56385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="428" mass="46119" checksum="E11C0C2C435BE9A8" modified="2019-10-16" version="1">MQIGEGIPRHALPSGFSSEPDASPWRLVPDPKNDFPWPRFASFLVDEVTVPLRHIYLDFNTTTPLAPSVGEAMQPFWDEHFLLPTQQHPAGLALGELVDTAREQVANLLGCDPFEVVFTSGGTEANNLAILGVCRAWQQAGKPPGRVIVSASEHDSVIAAANSLQFDGWHIEYLDVDPDGRVDPEQLDGMLQHDTALVCVQAACSISGVLQPVRQVADICHARGVLLHCDAAQLAGKQPIDTGSLRADTIAISGHKMYGPKGIGALYVRRGLKLSPILYGEAQEMGLRPGSGNITGEIGLGAAAKMAARGAEDAADAMAALRDRFEDRLQQAISPTPRVLGNQVSRLPNTSLITLPIRVPLQFNKATSDLVISRPRCAQPQDWMTRCLVAIGLSEQQIACTLRVSVGWTTSQESVDQAADQIIRALEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITK5</accession>
    <name>A0A518ITK5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glutamate dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">gdhA_1</name>
        <name evidence="9" type="ORF">Mal33_24160</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3 7">Belongs to the Glu/Leu/Phe/Val dehydrogenases family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004353">
        <property type="term" value="F:glutamate dehydrogenase [NAD(P)+] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05313">
        <property type="entry name" value="NAD_bind_2_Glu_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminiacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006095">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033524">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006096">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006097">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH_dimer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014362">
        <property type="entry name" value="Glu_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033922">
        <property type="entry name" value="NAD_bind_Glu_DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00208">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02812">
        <property type="entry name" value="ELFV_dehydrog_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000185">
        <property type="entry name" value="Glu_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00082">
        <property type="entry name" value="GLFDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00839">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="SSF53223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00074">
        <property type="entry name" value="GLFV_DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 3 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ELFV_dehydrog" evidence="8">
        <location>
            <begin position="232"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="156"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="144"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="239"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="270"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="409"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalysis" evidence="6">
        <location>
            <position position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000185-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000185-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000185-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV56426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="476" mass="52294" checksum="5771B6ED547D22A6" modified="2019-10-16" version="1">MLGPVDTLTKRQAITTEIGNTMPNKATWIDTCSDTECFMQGLERRNPGELEFHQAVREFVETVMPFVLKHRKYKDAQILERMTEPDRIVIFRVTWEDDAGNIRANRAWRVQFNNSIGPYKGGMRFHPDATLSVLKFLGFEQTFKNSLTGLPMGGAKGGANFNPKGKSDREVMRFCQSLMIELHRHIGEDTDVPAGDIGVGAREISYLFGQYKRLENRFAGILTGKGLTFGGSLVRTEATGYGCVYFCENMLNHVDDSLKEKTCVVSGSGNVAIYTAEKAAELGARVVVMSDSSGFIHDPAGIDAEKLAFIKNLKEVRRGRIAEYADKFEGVTFHPEERPWNVPCDVAFPCATQNEISLDDAKALIANGVKAVCEGANMPTELAGAHAFLEAGILYAPSKAANAGGVAVSGLEQSQNALRLSWSREEVDEKLKTIMRDIHDKCVEHGQTDGFVNYVLGANIAGFIKVADAMLAYGVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITM3</accession>
    <name>A0A518ITM3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Mannosyl oligosaccharide glucosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_24270</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 63 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004573">
        <property type="term" value="F:Glc3Man9GlcNAc2 oligosaccharide glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009311">
        <property type="term" value="P:oligosaccharide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031335">
        <property type="entry name" value="Glyco_hydro_63_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004888">
        <property type="entry name" value="Glycoside_hydrolase_63"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10412">
        <property type="entry name" value="PTHR10412"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03200">
        <property type="entry name" value="Glyco_hydro_63"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_hydro_63" evidence="2">
        <location>
            <begin position="709"/>
            <end position="798"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="897" mass="103522" checksum="7834CAA5A9479CDD" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITS0</accession>
    <name>A0A518ITS0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Translational regulator CsrA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">csrA</name>
        <name evidence="3" type="ORF">Mal33_24740</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CsrA/RsmA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048027">
        <property type="term" value="F:mRNA 5'-UTR binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044781">
        <property type="term" value="P:bacterial-type flagellum organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006402">
        <property type="term" value="P:mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045947">
        <property type="term" value="P:negative regulation of translational initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902208">
        <property type="term" value="P:regulation of bacterial-type flagellum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006109">
        <property type="term" value="P:regulation of carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.4380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00167">
        <property type="entry name" value="CsrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003751">
        <property type="entry name" value="CsrA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036107">
        <property type="entry name" value="CsrA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02599">
        <property type="entry name" value="CsrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117130">
        <property type="entry name" value="SSF117130"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1005">Bacterial flagellum biogenesis</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0810">Translation regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="65" mass="7115" checksum="65A3942524A51CD3" modified="2019-10-16" version="1">MLVLARNPGQSIYICGKVIRVTVVRVLGNRIYLGFDAPREVDIVRSELVDDLGDDGDSANIKVEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IU10</accession>
    <name>A0A518IU10_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminotransferase</fullName>
            <ecNumber evidence="1">2.6.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_25630</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.-" evidence="1"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004838">
        <property type="entry name" value="NHTrfase_class1_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00105">
        <property type="entry name" value="AA_TRANSFER_CLASS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="2">
        <location>
            <begin position="33"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="376" mass="41175" checksum="FE6EA5B54C13B2F6" modified="2019-10-16" version="1">MTKSTHPWLADRTAAFDSSGIRRVFDLAATLKDPINLSIGQPDFDVPDPVKQACIAAINSGKNAYSQTQGIAPLRDKLQSQLDAQYGHADRKVFVTSGTSGGLVLSMFAMVNPGDEVIFFDPFFVMYPPLIKLVGGVPVPIDTYPDFKIDIQKVADAITPRTKMILLNSPGNPTGVIATEQEQRELAALAAERGIALVSDEIYSRFCYADRFISPAEFNDQTIVIDGFSKSHAMTGWRVGFVHGPTEVVETMTKLQQYSFVCAPQPAQWAALEAIDVDVDDYRRQYQGKRDRIIDALKDDYEIEVPGGAFYIFPKVPWGTGTTFVEAAIAAGLLIIPGGIFSGRDTHFRISYAASDQTIDRGIEVLKQLARSGPKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IU37</accession>
    <name>A0A518IU37_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_25950</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="422" mass="46817" checksum="99FA33D7929A5A45" modified="2019-10-16" version="1">MNTLLLVTDQPFWRRENGSQQRSWALLQFLKSQGFHATCFYMVPLTDSDILATRELGLQIVAFDPNGSWFAKRVQGIANMFGRRRRKAKRPASQAAGVSKSPPGTLQTYRWPAAPAQFQKLVARLHPDLVLCNYVIWGNLLEAFPSGQRPFLAVVDTQDVLHQRQQSFSRYGADHWIEITRDEEAQALGLFDLILAAQADEAKTLRAMVPEVDVVQVGHDHDRHARPDAIDPPRPLPDAPVRIGMIGSGNAANRDGLRWFIDEVWNNGLSAQNVELVVAGSLSDEMDGPTDSGSPQVRCLGVVQPLDAFYDQVDVVINPIRFGSGIKIKTIEAFRFGKPLVVHPHSTQGLSEAAKEAVLVADTAAEFSAACQRLVDSAAMRREMSQRMLQFDRTELSAKSVYSDLVAWLRQHDLCVASGRPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IU41</accession>
    <name>A0A518IU41_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">N-glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_25910</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00920">
        <property type="reaction ID" value="UER00891"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025993">
        <property type="entry name" value="Ceramide_glucosylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12726">
        <property type="entry name" value="PTHR12726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="283"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="314"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV56599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="425" mass="47104" checksum="050239B0D52D2C3D" modified="2019-10-16" version="1">MISIAAVYSIALLLWSIANWGFAWFFAARIVRPGIGKHGLHENQPFAPKASVLLSLRGCDPFLEQTLRGLLEQSYPDFEVIVVVDNRCDPAWDVAMQVKSERDAQDRIRIVELLNPLPTCSLKCSSLVQATSQISSTSQVVVLVDADVVPHANWLRDVVQPLSDPKVGVVTGNQWFDPRRRDTGSVLRSLWNSGALVATAINANPWAGTCAIRTADLLSSGLVDDWKTSVVDDGPIKAAMTRLGLRVHFDPNLIMVNRDQCTTAFVGRYVTRMLTWSRVYEPTFAGTVVHAAALALFTAGWLLFLIAAICWGDWPAAALLTSSMLIANGCMFLSWRTVRVAVGEAVATRGDSLHRMSWSEAAQVFALLPVCQLTHVFCTIKAIWVRQVNWRGITYRLHSQRRVEMVAYRPYVDNQQVPSEANLSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IU48</accession>
    <name>A0A518IU48_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Macrolide export protein MacA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">macA_2</name>
        <name evidence="5" type="ORF">Mal33_26000</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="14"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="domain" description="HlyD_D23" evidence="4">
        <location>
            <begin position="56"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="117"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV56608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="421" mass="46168" checksum="FFDD564F1650228C" modified="2019-10-16" version="1">MTNKKPKRSWVRRLVLGGGMLFGVLAVAGFFYVRSVSNALPELRTVDIQRRDLVITIGTTGTIEPDEVVQVGPEVAGKIVRFGVDPDDKQKSIGVGARVSKGTVLFEIDPQQFEMGLQKAQAAYGLAQADIGRLEAQLAQASRNLQRATQLRATNTQSAFDEIQTAHEMAAAQLAVGQARLKQAETEVRHAEIHVEQTTVRSPIDGIVIDRRANLGQHVHAGHPGLFLLSKDLDHMRIRASVSESDIGKVKLGQPATFTVDAHRNDTMTGRVEEILFNARRQGNFVTYDVVIGIDPTDIELFPHMTADVEFEVLRRDHAWLVPNGALRWWPDSKQLESGDLLVDRPQQQDNARGPSEGEQACVWVAAGDGRVRPLKVRVGVDDGVQTEVQGDGFAEALPIVVGTVDRTTLARIIPTAKTIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUB5</accession>
    <name>A0A518IUB5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DNA polymerase beta</fullName>
            <ecNumber evidence="4">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="primary">polX</name>
        <name evidence="21" type="ORF">Mal33_26830</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="17">Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00141">
        <property type="entry name" value="NT_POLXc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.210.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002054">
        <property type="entry name" value="DNA-dir_DNA_pol_X"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010996">
        <property type="entry name" value="DNA_pol_b-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028207">
        <property type="entry name" value="DNA_pol_B_palm_palm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027421">
        <property type="entry name" value="DNA_pol_lamdba_lyase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037160">
        <property type="entry name" value="DNA_Pol_thumb_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022312">
        <property type="entry name" value="DNA_pol_X"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002008">
        <property type="entry name" value="DNA_pol_X_beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003583">
        <property type="entry name" value="Hlx-hairpin-Hlx_DNA-bd_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004013">
        <property type="entry name" value="PHP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003141">
        <property type="entry name" value="Pol/His_phosphatase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016195">
        <property type="entry name" value="Pol/histidinol_Pase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029398">
        <property type="entry name" value="PolB_thumb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022311">
        <property type="entry name" value="UCP005047_YshC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14792">
        <property type="entry name" value="DNA_pol_B_palm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14791">
        <property type="entry name" value="DNA_pol_B_thumb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14716">
        <property type="entry name" value="HHH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02811">
        <property type="entry name" value="PHP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005047">
        <property type="entry name" value="UCP005047_YshC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00869">
        <property type="entry name" value="DNAPOLX"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00870">
        <property type="entry name" value="DNAPOLXBETA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00278">
        <property type="entry name" value="HhH1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00481">
        <property type="entry name" value="POLIIIAc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00483">
        <property type="entry name" value="POLXc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47802">
        <property type="entry name" value="SSF47802"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89550">
        <property type="entry name" value="SSF89550"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-0227">DNA damage</keyword>
    <keyword evidence="15" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8" id="KW-0237">DNA synthesis</keyword>
    <keyword evidence="13" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="21" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="21" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0488">Methylation</keyword>
    <keyword evidence="21" id="KW-0540">Nuclease</keyword>
    <keyword evidence="10" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0915">Sodium</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <keyword evidence="12" id="KW-0832">Ubl conjugation</keyword>
    <feature type="domain" description="POLXc" evidence="20">
        <location>
            <begin position="1"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="domain" description="HhH1" evidence="18">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="domain" description="HhH1" evidence="18">
        <location>
            <begin position="93"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="HhH1" evidence="18">
        <location>
            <begin position="128"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="POLIIIAc" evidence="19">
        <location>
            <begin position="342"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00024632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00025610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="SMART" id="SM00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="SMART" id="SM00481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="SMART" id="SM00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="QDV56685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="578" mass="63749" checksum="7B0F7CC782E64069" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUI9</accession>
    <name>A0A518IUI9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Carboxylesterase NlhH</fullName>
            <ecNumber evidence="3">3.1.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">nlhH_1</name>
        <name evidence="3" type="ORF">Mal33_27350</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.1.1" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080030">
        <property type="term" value="F:methyl indole-3-acetate esterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022066311" evidence="1">
        <location>
            <begin position="29"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="domain" description="Abhydrolase_3" evidence="2">
        <location>
            <begin position="63"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="297" mass="32111" checksum="6D47CC2B9372D4E1" modified="2019-10-16" version="1" precursor="true">MMRRFQRLSLSIGLPLLLLVLVPMTASCQQIPPTHRDLAYDDQHASQRLDVYLAKSETPVPAMVYIHGGGWRGGSKNRLPQWLSNAVAQGWLSVVSVEYRFTDVAPHPAQTDDCLRAIQFVRSNAAAWNIDPDRIGVTGGSAGGHLSLWVALHDDVADAQATDPIKKQSSRVACAVSFAGPTDWSLLSDIEHKHPAYRQLLGYQPGTAVAEMDADKMKDVSPISFVSSDDPPIMQVHGDADDIVPIKHARRMDKQLQEAGVTAELVVVPGANHGVAGAGGDAGKRASEFVRETIGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUK3</accession>
    <name>A0A518IUK3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Leader peptidase PppA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">pppA</name>
        <name evidence="4" type="ORF">Mal33_27560</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010627">
        <property type="entry name" value="Pept_A24A_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06750">
        <property type="entry name" value="DiS_P_DiS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="62"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="133"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="181"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="212"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="250"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="291"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="336"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="367"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="domain" description="DiS_P_DiS" evidence="3">
        <location>
            <begin position="70"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="394"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF06750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV56757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="423" mass="46030" checksum="8E474F44F31AB501" modified="2019-10-16" version="1">MNNPTAMPRKRRHRRNPNWPLISVVGGLAVAAVLYVIAAVSLHGHHHHNTSDLVVPRLLDLFVVAWFFWFGSSIGSFLNVVAWRMPRGRSINGFSACPFCAVPIRAYDNVPVFGWLNLRGRCRACRLPIAARYPIVEALVGVSIMLVGLLGLYSGGENLPFAGARGDAHGPLRMPHITAEIIAINVYQIAILTGAWAFALVRVDGFRLPARLVQFFLALSIVPMLAWPQLQQVPWQLRTQPGGDYDSHLVALFYIVTAVAAACVLARMMARYVCPTADPKLDPLGKDTARLIDLILMLTLPGIVLGWHALIAVCAVSIVAAILLRNIFPSRGGYEWLMAVIPAAMALHLAFWRPLAQLAMWPAPNHSPAVILGWLTAVLLLAAGLQTAAPEPIAAAIPTDSDGDNTADSEMDPEPTDNQRTSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUW1</accession>
    <name>A0A518IUW1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phosphoserine phosphatase 1</fullName>
            <ecNumber evidence="1">3.1.3.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">pspA_1</name>
        <name evidence="1" type="ORF">Mal33_28730</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.3.3" evidence="1"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036424">
        <property type="term" value="F:L-phosphoserine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="SSF53254"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="195" mass="21901" checksum="132BB74CA76637A1" modified="2019-10-16" version="1">MLSILLVRPGATDFDDQRRIKGSLDMPLSECGRQQVRRTAQDVATFQLQAVYSAPCESALTTSAELIAGRDIRVKAIPNFRNIDHGLWHGKLVDDVRRQQPRLYRQGEEYPNLICPPEGETVEEAKQRVFKALRKVIKKHRDGAIALVIPDPLASVVHCILSGEGPKSLWLSEVDTGNWELIELESLELREPALV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IV64</accession>
    <name>A0A518IV64_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Type 2 DNA topoisomerase 6 subunit B</fullName>
            <ecNumber evidence="3">5.6.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Type II DNA topoisomerase VI subunit B</fullName>
            <shortName evidence="3">TopoVI-B</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">top6B</name>
        <name evidence="6" type="ORF">Mal33_29560</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Relaxes both positive and negative superturns and exhibits a strong decatenase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>ATP-dependent breakage, passage and rejoining of double-stranded DNA.</text>
            <dbReference type="EC" id="5.6.2.2"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer. Heterotetramer of two Top6A and two Top6B chains.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TOP6B family.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.2" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003918">
        <property type="term" value="F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006268">
        <property type="term" value="P:DNA unwinding involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00823">
        <property type="entry name" value="TopoIIB_Trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00322">
        <property type="entry name" value="Top6B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010979">
        <property type="entry name" value="Ribosomal_S13-like_H2TH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005734">
        <property type="entry name" value="TopoVI_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015320">
        <property type="entry name" value="TopoVI_B_transducer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10871:SF4">
        <property type="entry name" value="PTHR10871:SF4"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09239">
        <property type="entry name" value="Topo-VIb_trans"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006553">
        <property type="entry name" value="TopoVI_B"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46946">
        <property type="entry name" value="SSF46946"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 3 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="HATPase_c" evidence="5">
        <location>
            <begin position="42"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="671"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="678"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="57"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="89"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="110"/>
            <end position="111"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="120"/>
            <end position="127"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="547"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV56955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="692" mass="75382" checksum="9AEA02E918015730" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVB9</accession>
    <name>A0A518IVB9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_30300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021866595" evidence="2">
        <location>
            <begin position="21"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="144" mass="15865" checksum="FC95554C3BFDB663" modified="2019-10-16" version="1" precursor="true">MTFKRALTLAGLVTATILLAGNDAQAQCSGGRGGAGGGSAGPGYALGQRYDPVAYQRDYALQQQRYLQNQQLYAMRQQTYQQQVAQKYQQRQDLLAARKERAMLKREARDARIAQLKATRQAEREAEASASESYASAETVVAMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVH4</accession>
    <name>A0A518IVH4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Signal transduction histidine-protein kinase BarA</fullName>
            <ecNumber evidence="4">2.7.13.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">barA_9</name>
        <name evidence="4" type="ORF">Mal33_30860</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.13.3" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="36"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="66"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="96"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="3">
        <location>
            <begin position="230"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV57085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="502" mass="56268" checksum="A037548FC7D4AAB8" modified="2019-10-16" version="1">MIDSIESTRKSAPSQAERDLFDLHALAIYRRTDRMFAYLMVLQWVVAIAAAYWFSPRTWDGVQSSMHPHLLMAIFGGGLLASLPVALAWRMPGHAITRYVIAISQVLFSSLLIHITGGRIETHFHIFVSLAFLAAYRDWKVLAPATLVIIVDHVIRDIWWPESIFGVATASHWRWLEHAAWVLFEDLVLAFTIRQSIREMRALALHTVQLEQARQVAEEASCVKGQFLASMSHELRTPLNGVIGMTELLADSPLSERQRRFVNACQSSGALLLRLINDILDFSKIEAGHLELEEHPFELQQLIEDVMSGMPPRLHERDVQLICRQDDSTPLHLLGDSHRLRQVLVNLLGNALKFTERGEITLRTARQHISDDRVTLLFSIEDTGIGIPADRMDRLFQSFSQVDSSIRRKYGGSGLGLSISKAIVHAIGGEIGVESHEGLGSRFWFAVNLRRDHDATNEFDSPAMPPSSFEVQPAPRHVAPAQVPFVPEAAVSLPSEFVGSNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVJ5</accession>
    <name>A0A518IVJ5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Type IV leader peptidase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_31090</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase A24 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000045">
        <property type="entry name" value="Prepilin_IV_endopep_pep"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01478">
        <property type="entry name" value="Peptidase_A24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="65"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="104"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="165"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_A24" evidence="3">
        <location>
            <begin position="18"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV57108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="187" mass="20590" checksum="37D051E3385F8D6A" modified="2019-10-16" version="1">MDTNTLIESLMYNWHVWLVAVVMIVAAVIDGMILKVPNWLTYPFIISGWVYAAMASGWNGLGYSLLGTFVGMMLLLVVRAVGGMGAGDVKLLAGLGAWMGASTAWWAFVWTTVVGGIIAVIMIAMSGNWFKHYAMFHQIIQEFVTIRNPEKLAAIARERKPTMKLLPYGIPMAIGSILYFAYAGMFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVP6</accession>
    <name>A0A518IVP6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_31620</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="80" mass="8929" checksum="4390219E8D906FEC" modified="2019-10-16" version="1">MNIELSEKTEKVARTIVESGRFTTVEAFLEAAAQAFMAQSCVPLPADKPTAEELKERFMPFRGKLKMSREEVVGPVIRSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVX7</accession>
    <name>A0A518IVX7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ</fullName>
            <ecNumber evidence="1">4.2.1.59</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">fabZ_1</name>
        <name evidence="1" type="ORF">Mal33_32450</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="4.2.1.59" evidence="1"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008659">
        <property type="term" value="F:(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008693">
        <property type="term" value="F:3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047451">
        <property type="term" value="F:3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004317">
        <property type="term" value="F:3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013114">
        <property type="entry name" value="FabA_FabZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30272">
        <property type="entry name" value="PTHR30272"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07977">
        <property type="entry name" value="FabA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="175" mass="19284" checksum="70B130CB2860C067" modified="2019-10-16" version="1">MAAKDLIFNLDDLDFDAPIGDLDEICKVNPQRHEMLQLTAIVGEDMQRNACAAYKDLSQDEFWVRGHMPGMPLMPGVVMLEAAAQLCSYFTQKHDLLGADMVGFGGVDEVRFRDPVLPGDRLVLMCELTRIRRGRMIVARFQGVVRGGLAVEGIIKGIPIPISALKETLAARSNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVX8</accession>
    <name>A0A518IVX8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Calcineurin-like phosphoesterase superfamily domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_32430</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallophosphoesterase superfamily. YfcE family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024654">
        <property type="entry name" value="Calcineurin-like_PHP_lpxH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12850">
        <property type="entry name" value="Metallophos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos_2" evidence="2">
        <location>
            <begin position="1"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="200" mass="21548" checksum="581D35047F81649B" modified="2019-10-16" version="1">MKLLLFSDLHRDRDAATALVELAKDADVMIGAGDFAIKRKGLADTIEILRTADCPAILVPGNGESVEELTQACRDWPQAHVLHGTAASVAGVSFFGIGGGIPTTPFGDWSYDFSEEEAAELLRLMAEQDVLVTHSPPWNCVDIDGSGTHRGSPTIRQAIEANKPRLVVCGHVHDSWEQTDRVGDSVVINAGPRGVWHTID</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IW79</accession>
    <name>A0A518IW79_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Endonuclease/Exonuclease/phosphatase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Mal33_33410</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNase I family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004536">
        <property type="term" value="F:deoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006308">
        <property type="term" value="P:DNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016202">
        <property type="entry name" value="DNase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00130">
        <property type="entry name" value="DNASEI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00476">
        <property type="entry name" value="DNaseIc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="SSF56219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2 6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="6" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endo/exonuclease/phosphatase" evidence="5">
        <location>
            <begin position="140"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="58"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV57337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="404" mass="44403" checksum="64AA94112BFCC2C5" modified="2019-10-16" version="1">MARRKSRKSPRLTTVIWTLVATVSSGGIGGYLKSDLPVLGPLVQRFISDEEEKLAGAFPAPSANGYPAATATNNPGYAQGYPPPGIDPRAIPTSANPARRYPPANPQAGTNYVQPTSAAMRPAPVQQAASRKPSDRLLIATFNIQVFGESKLGKPEVVEVLAAVVRQFDIVAIQEVRAKADNILPDFVSAINADGSRYSFLIGPRLGRSNSKEQYAYIFDTNRIEHDPQAVGTMQDPNDLLHREPFVARFRARTASPQHAFTFWLVDTHTDPDEVPEEVAALADVFRVMQTARADEDDVILLGDLNASEKQLGPLGQIPGITWVVRNAMTNTRQNKAYDNILFHAQATQEFTGRWGVFDLERAFGLSREQALDVSDHLPVWAEFQIWEAPHQARVAEAAPAMQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWB8</accession>
    <name>A0A518IWB8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">Carbonic anhydrase</fullName>
            <ecNumber evidence="3 6">4.2.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Carbonate dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">icfA</name>
        <name evidence="7" type="ORF">Mal33_34000</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Reversible hydration of carbon dioxide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>H(+) + hydrogencarbonate = CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:10748"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="EC" id="4.2.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the beta-class carbonic anhydrase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.1" evidence="3 6"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004089">
        <property type="term" value="F:carbonate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015976">
        <property type="term" value="P:carbon utilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00884">
        <property type="entry name" value="beta_CA_cladeB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045066">
        <property type="entry name" value="Beta_CA_cladeB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001765">
        <property type="entry name" value="Carbonic_anhydrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015892">
        <property type="entry name" value="Carbonic_anhydrase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036874">
        <property type="entry name" value="Carbonic_anhydrase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11002">
        <property type="entry name" value="PTHR11002"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00484">
        <property type="entry name" value="Pro_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00947">
        <property type="entry name" value="Pro_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53056">
        <property type="entry name" value="SSF53056"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00704">
        <property type="entry name" value="PROK_CO2_ANHYDRASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00705">
        <property type="entry name" value="PROK_CO2_ANHYDRASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV57390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="221" mass="24137" checksum="1E266502609FE749" modified="2019-10-16" version="1">MQKLIKGIHQFQRESFVPLQGLFEQLAKGQSPDTLFITCSDSRIDPTLLTRTPPGDLFILRNAGNIVPPHGAGGGEAATIEFAVAGLGVKDIIICGHSHCGAMKGILDPDQLVEMPAVAAWLSNADSTRRIMKENYSDLEGDRLLSATVEENVLVQLENLRTLPSVAARLAKGDLHLHGWVYKIETGQVFAYDVESSQFLKLTDCDPPVEPAVQHRKTNLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWP1</accession>
    <name>A0A518IWP1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">(R)-stereoselective amidase</fullName>
            <ecNumber evidence="2">3.5.1.100</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ramA</name>
        <name evidence="2" type="ORF">Mal33_35210</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.5.1.100" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="SSF56317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CN hydrolase" evidence="1">
        <location>
            <begin position="35"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="351" mass="38913" checksum="58D21996504DE69C" modified="2019-10-16" version="1">MIGGFDGVHAGRFDDSFRRRTYHFTREAKEPMKNFRVASVQFNHLPGDKAGNLAIMRPFVEAAAGQGAELVCFPECCVTGYWHLRKLSSQQLAELAEPVPDGPTTQTLLAWAAEHQITIGAGLIEVDAAGVLYNSYVVATPAGEVHCHRKLHCFISEFMESGDTYTLFDLPNGWRVAVLICYDNNILENARACALAGAEVILAPHQTGGCNSGSPQAMSVIDRAVWDARQTDPKAIEAEITGDKGRGWLMRWLPSRAHDNGVFYVFSNGIGPDDDEVRTGNAMILDPYGRVIVETCKAGDDMVVADLDPTLRDRCTGVRWMRARRPDLYRSLARRRGDEQDTRAVRFDHRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWS6</accession>
    <name>A0A518IWS6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_35530</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="289" mass="30894" checksum="3065D792390349F8" modified="2019-10-16" version="1">MIKKAMYTVALATMTIQTSSAKGPCAPRVGCGCSQPVSVVSGCSSSSSNIVHDNPSELNILLTTELVALRKEVAELKTAAAETSQALEQAETLVGTQKSRMEQLIADSLKETKRAEAAEKALKESKAAMAAATKANEQALAKVKQQLADTSKKVEQLTSKNAELSKQIAEENKRKEEEKKRREQAKAKRDEEAMKAKKAAEEKAKKEAEAKKAKMEAEVKAKKEAEAKKAAEAKAKQEAEAKKAAEAKAKQEAEAKKAAEAKAKQEAEAAAAKAKEAAEAKPADEKSDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWT5</accession>
    <name>A0A518IWT5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cupin domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_35360</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin_2" evidence="1">
        <location>
            <begin position="41"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="112" mass="11874" checksum="2DB63EE12B236DD9" modified="2019-10-16" version="1">MAISHAKSGEIIDVGPLGDELPATKTSALLKSDEMELLRLVLPAGKTIAEHKAPGEITVHCLEGRVQFTTLGATLELTAGRLLHLPAGEPHALHAIEDSSLLVTIVRRPSKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWY2</accession>
    <name>A0A518IWY2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Delta(12)-fatty-acid desaturase</fullName>
            <ecNumber evidence="4">1.14.19.6</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">desA</name>
        <name evidence="4" type="ORF">Mal33_36100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.14.19.6" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102985">
        <property type="term" value="F:delta12-fatty-acid desaturase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="47"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="73"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="225"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="250"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="domain" description="FA_desaturase" evidence="3">
        <location>
            <begin position="72"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV57597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="382" mass="42821" checksum="7C41FD6EEC24781A" modified="2019-10-16" version="1">MSIVMEPEDASPGLNSSQESAPLPTRKQVLAAIPEDCFDRNTFKSSVYMVISIVLTVGSGLLAYLFLPMTWAWLPAWIAYAAVTGTIATGCWVIAHECGHRAFSKHNWYQDAVGFTLHSALLVPYFSWQRSHALHHARTNHMDLGETFVPTRDTTAAGKAWIRWQEIMGDEAFAVVIMAARLLVGWPVYLLTGASGGPARGVTNHFWPAKPFSAAMFPGKWRTKVWLSDLGVLATLGLLGWWAYAEGSFLPVLAVYVGPYLFTNAWLVLYTWLQHTDVDVPHFDEDEWTWVKGAFMTIDRPYGPVFDFLHHRIGSTHVAHHIDARIPHYNAVRATEALKSAFPDLYLYDPTPIHKALWKVATHCNVVSKADVGWKFNGKTRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IX88</accession>
    <name>A0A518IX88_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Aminodeoxyfutalosine synthase</fullName>
            <shortName evidence="6">AFL synthase</shortName>
            <shortName evidence="6">Aminofutalosine synthase</shortName>
            <ecNumber evidence="6">2.5.1.120</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Menaquinone biosynthetic enzyme MqnE</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">mqnE_1</name>
        <name evidence="6" type="synonym">mqnE</name>
        <name evidence="8" type="ORF">Mal33_37110</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>3-[(1-carboxyvinyl)-oxy]benzoate + H2O + S-adenosyl-L-methionine = 6-amino-6-deoxyfutalosine + H(+) + hydrogencarbonate + L-methionine</text>
            <dbReference type="Rhea" id="RHEA:33075"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:64286"/>
            <dbReference type="ChEBI" id="CHEBI:76981"/>
            <dbReference type="EC" id="2.5.1.120"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="6">Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Quinol/quinone metabolism; menaquinone biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the radical SAM superfamily. MqnE family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.120" evidence="6"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00079"/>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102573">
        <property type="term" value="F:aminodeoxyfutalosine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009234">
        <property type="term" value="P:menaquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00993">
        <property type="entry name" value="MqnE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045567">
        <property type="entry name" value="CofH/MnqC-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034405">
        <property type="entry name" value="F420"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020050">
        <property type="entry name" value="FO_synthase_su2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022432">
        <property type="entry name" value="MqnE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43076">
        <property type="entry name" value="PTHR43076"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19288">
        <property type="entry name" value="CofH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00343">
        <property type="entry name" value="aminofutalosine_synthase_(mqnE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03700">
        <property type="entry name" value="mena_SCO4494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00423">
        <property type="entry name" value="TIGR00423"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4 6" id="KW-0408">Iron</keyword>
    <keyword evidence="5 6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="6" id="KW-0474">Menaquinone biosynthesis</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Radical SAM core" evidence="7">
        <location>
            <begin position="85"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV57698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="409" mass="46779" checksum="8DA61CE36E3C7BC5" modified="2019-10-16" version="1">MESVLNTNEPPSDGRKSITFKVNPNTNQMIATEINARLRTIRDKVESQERLTMDDGLFLYQPDVPLHEVGELADLVRQRMNGNVAYYNINTHLNPTNVCVYRCRFCAFRADLRDPKGYAMDDEQVIARGQEATDNGCTEMHIVGGLHHQRPYEWYRGVLSTLSENFPKLHLKAWTPVEINWFEFQTKNSTEWVMNDMREAGLGSLPGGGAEIFHPEVRDQICEHKANTHAWFHTHRTAHQLGIRSNCTMLYGHIEQAYHRVDHLLRLRELQDETGGFQVFIPLAFHPENTKLSHLKKPSALDDLRNVAVSRLLLDNIQHIKAYWIMLGIGTAQTALSYGADDIDGTVRHELIYHDAGATTPEFLSVDRIRELIIEAGRVPVERNTIYQEVIRDPNDFSNWSIGETLPVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IX91</accession>
    <name>A0A518IX91_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">3-deoxy-D-manno-octulosonic acid transferase</fullName>
            <shortName evidence="9">Kdo transferase</shortName>
            <ecNumber evidence="3 9">2.4.99.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6 9">Lipid IV(A) 3-deoxy-D-manno-octulosonic acid transferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">waaA</name>
        <name evidence="11" type="ORF">Mal33_37130</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>CMP-3-deoxy-beta-D-manno-octulosonate + lipid IVA (E. coli) = alpha-Kdo-(2-&gt;6)-lipid IVA + CMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:28066"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58603"/>
            <dbReference type="ChEBI" id="CHEBI:60364"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="ChEBI" id="CHEBI:85987"/>
            <dbReference type="EC" id="2.4.99.12"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Bacterial outer membrane biogenesis; LPS core biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the glycosyltransferase group 1 family.</text>
    </comment>
    <dbReference type="EC" id="2.4.99.12" evidence="3 9"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00958"/>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043842">
        <property type="term" value="F:Kdo transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009244">
        <property type="term" value="P:lipopolysaccharide core region biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11720">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007507">
        <property type="entry name" value="Glycos_transf_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038107">
        <property type="entry name" value="Glycos_transf_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039901">
        <property type="entry name" value="Kdotransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42755">
        <property type="entry name" value="PTHR42755"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04413">
        <property type="entry name" value="Glycos_transf_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9" id="KW-0448">Lipopolysaccharide biosynthesis</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_N" evidence="10">
        <location>
            <begin position="43"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="61"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="8">
        <location>
            <position position="130"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="8">
        <location>
            <position position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR639901-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR639901-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QDV57700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="437" mass="48436" checksum="BCBF31D42D114975" modified="2019-10-16" version="1">MTYLLNIAYLLAAVAISPFLVWRSLRTGKYRAGWSAKLLGNVPLREGNQPCAWLHAVSVGEVNLLSNVVQRLQQSRPDMQIVISTTTATGMQLARTRFPEHMVFYCPLDFSWAVRRAFRRIRPDVLVLSELELWPNLIAIARQKGAEVVVINARLSERSFRGYRRFASLLRPTFRRLSLVLAQDETYARRFLQLGVDHSRVRVTGSIKFDGARTDRHAPEVVALRKLSAASKEQIVWIAGSTQAPEERIALDIYRRLADRFPQLRLILVPRHPERFKAVADQVVGAGLKLRRRSELQTPAESWPGDTVLLVDTVGELGCWWGLSDIAFVGGSMGSRGGQNMLEPAGFGAAVSFGPNTRNFRDIVAQLLAADAATVVRDRGALEQFVVNCVEDPAARRQQGRRAQVLVVGGQGAIDRTIAAVEQLLPAASPSSTRQAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IX93</accession>
    <name>A0A518IX93_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">VWFA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_37180</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13768">
        <property type="entry name" value="VWA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="VWFA" evidence="3">
        <location>
            <begin position="129"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="416"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="899"/>
            <end position="918"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV57705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1412" mass="151549" checksum="75BB72101B13E3F9" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXI7</accession>
    <name>A0A518IXI7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_38010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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        <property type="entry name" value="DUF1559"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07596">
        <property type="entry name" value="SBP_bac_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="323" mass="34952" checksum="9DC48B648342090B" modified="2019-10-16" version="1">MFCCKGSVRSKRLRAGFTLVELLVVIAIIGILVGLLLPAVQAAREAARRMSCSNNLKQIGLAMHNYHDTHQRFPYAFRTLDNPPGPSGVPAGITHVRDTWFHRLLPMVEQRGLYDSYEADNSMFINHSNLKMQIETVVPAFVCPTNPGYGGGAANQANGFQGTYGVCMSGSETLGITFTTNGKGMFYNASKTKFRDILDGTTNTIMVGEGIARPMDNVGGHGDLGQYWGGATWGATGFTTAEPPNTSLPDRPHSCKSTSVLQAPCLSTSSTRGEQFNFSRSYHPGGVQVTLADASVRFAAETIDQQIYQNLGDKADSQVIGEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXJ8</accession>
    <name>A0A518IXJ8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC-2 family transporter protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Mal33_38290</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
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        <property type="protein sequence ID" value="QDV57814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032688">
        <property type="entry name" value="ABC2_membrane_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12679">
        <property type="entry name" value="ABC2_membrane_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="201"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="247"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="287"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="310"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="740"/>
            <end position="759"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV57814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="763" mass="84367" checksum="523A21C91AA42524" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXL5</accession>
    <name>A0A518IXL5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_38490</name>
    </gene>
    <organism evidence="1 2">
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        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetia</taxon>
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    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="242" mass="26465" checksum="F31D8F7ED21C0056" modified="2019-10-16" version="1">MMLWIGDNQHPEFRDAWTWASQSGQCQHRDSIDAAVEQPVARSTPRIVIARPDRQPLPAAAFNALQQQYPLASYATLLGSLCEGEQRTGTPWPHCQRIYWHRWSFQLVAWSGLNPQASPSAPATSGCIGIVSRSRWIGSGVVDSLRHASIPCVAVAPQQLAVAGPYSDLLWDDSVIATLDDWQAQAAAVAAHAGTARHHWLVSSPRVETWHALQAAGFEALHSKPLDLDGILDSLNRRTATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXU5</accession>
    <name>A0A518IXU5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Competence protein A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_39200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="318"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="477"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="491"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="518"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="541"/>
            <end position="577"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="577" mass="62220" checksum="8C6D7EAD005FA26C" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXX6</accession>
    <name>A0A518IXX6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Toxin HigB-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">higB-2</name>
        <name evidence="1" type="ORF">Mal33_39610</name>
    </gene>
    <organism evidence="1 2">
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        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="129" mass="14879" checksum="FB0BE99795E0F9FF" modified="2019-10-16" version="1">MRRSESVGPASLLHFFYLDEFLADWKTLFPTDDDEVSLHELEMRLMRDPTSAPIVSGTGGLRKLRFALEGSDRGARGGIRVCYSFFPEHHIVLMVMAYPKNRQDNLSGHEKQGIKAYLEQTKRWLDQHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IY30</accession>
    <name>A0A518IY30_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FeoA domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_40090</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046914">
        <property type="term" value="F:transition metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007167">
        <property type="entry name" value="Fe-transptr_FeoA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038157">
        <property type="entry name" value="FeoA_core_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008988">
        <property type="entry name" value="Transcriptional_repressor_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04023">
        <property type="entry name" value="FeoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00899">
        <property type="entry name" value="FeoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50037">
        <property type="entry name" value="SSF50037"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FeoA" evidence="2">
        <location>
            <begin position="4"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="82" mass="8576" checksum="91AD7CA8792B5D6B" modified="2019-10-16" version="1">MHARSLADLPANSSGMVLRFNLSDEDSIRIRTLGICPGMTVEVVQNGDPLILASAGTRIGISRRIAAQVMIEDEPVAAGAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IY39</accession>
    <name>A0A518IY39_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_40260</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.10.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038296">
        <property type="entry name" value="ParD_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="80" mass="8955" checksum="F1D683F9FE80961E" modified="2019-10-16" version="1">MSTGIPQDMEPFVQRMVAGRRFLSEQDVVTEGLRLLQARETLREEVAKGFASLDAGHGVPADQVFARAEQRIAEIERGER</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYC1</accession>
    <name>A0A518IYC1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Long-chain-fatty-acid--CoA ligase</fullName>
            <ecNumber evidence="3">6.2.1.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">lcfB_3</name>
        <name evidence="3" type="ORF">Mal33_41040</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="6.2.1.3" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004467">
        <property type="term" value="F:long-chain fatty acid-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="1">
        <location>
            <begin position="41"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding_C" evidence="2">
        <location>
            <begin position="474"/>
            <end position="550"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="562" mass="62876" checksum="6E1E049989D01A4A" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYJ0</accession>
    <name>A0A518IYJ0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytochrome c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Mal33_41550</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00034">
        <property type="entry name" value="Cytochrom_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13442">
        <property type="entry name" value="Cytochrome_CBB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="64"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="6">
        <location>
            <begin position="147"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="6">
        <location>
            <begin position="348"/>
            <end position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV58138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="489" mass="53683" checksum="D45664527198257B" modified="2019-10-16" version="1">MHDNLSKTQVGIRKVRSPIGRMQTRAGKRHGGAATIGLMRGVAFGLGSWPSLDRMKRMDAEKRRMIALGIALLALLILPGCGTEPPDFRMNRVFAHKMEIHGAELDTAIDDTQIAITQLFGTPDEPLLPAVLTENPDFQSLIQLENLQRAAGAVASDRDGTDRGLYRKHCSQCHGISGDGNGPASNLLNPYPRDFRMGVFKFKSTQYGAKPTVDDLVRTLRQGMPGTSMPSFHLYPDEDLTALAQYVIYLTLRGEVERAMYRDAANELGYGDPDQTPQDRLLAMELKESDPEAYQEQWDAIEDYVVAAASRWIDAPEQVVSIAPPPEKIPAWPLAADATADQKAEMTASIARGRALFGGKVANCAICHGADGRGDGQVNDYDDWTKEWTMRNGLDPKDPEKKQVVREYLALGAHKPRNILPRDMHAGAFRGGDQPQDIYRRIVQGIDGTPMPAINLVDQPSGSGLTTGDVWDIVHYVLSLSQTGRGEAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYM5</accession>
    <name>A0A518IYM5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_42060</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="176" mass="19550" checksum="CD16D3ADF6FF6148" modified="2019-10-16" version="1">MFCFVACAVMKRVRGSGRIGRFDAPKWAAVGQPRATPWVFDRAHSRRIYVTFGNVWRDRVRAAPLGLGSFVWRRFPRALPWAGVVPARWALGICGCLLFGGVFPGRCPGLTWGRPDWAWVNGRRVGIVVGANKKPSFFGNEGLSGNSQFCVICVWLSNRLDYIGPNLAIKSAVRLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYN3</accession>
    <name>A0A518IYN3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">P-loop containing nucleoside triphosphate hydrolase</fullName>
            <ecNumber evidence="6">3.6.3.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Mal33_42200</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.6.3.-" evidence="6"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042953">
        <property type="term" value="P:lipoprotein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015854">
        <property type="entry name" value="ABC_transpr_LolD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24220:SF654">
        <property type="entry name" value="PTHR24220:SF654"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="30"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="66"/>
            <end position="73"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV58203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="264" mass="29253" checksum="FF3355E3749ECFF1" modified="2019-10-16" version="1">MINPAVDPTQSASNQSSGTQPIAAADGTILAVRGLVKSYHKNRIEVPVLRGVDFDIEVGSMTSLVGRSGSGKSTLMHLMATLDQPDAGEVSFEGSRIDNASARQRDFYRNHQIGMIFQFYHLLPELTALENVMVPTMISRRLFSFLRVKKTARQRAEQLLEMVGLTHRTHHRPSEMSGGEMQRAAIARALMNNPTLLLADEPTGNLDSETGHGILELLRKLNDENNLTIVMITHDDAIARQADRMVRLENGLVVDQGEAFRVIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYU9</accession>
    <name>A0A518IYU9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cation/acetate symporter ActP</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">actP</name>
        <name evidence="8" type="ORF">Mal33_42810</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1730.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038377">
        <property type="entry name" value="Na/Glc_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001734">
        <property type="entry name" value="Na/solute_symporter"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00474">
        <property type="entry name" value="SSF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50283">
        <property type="entry name" value="NA_SOLUT_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="47"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="78"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="122"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="153"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="183"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="393"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="428"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="473"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="522"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="547"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="578"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="616"/>
            <end position="638"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV58263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="644" mass="68561" checksum="E351189E014415C9" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ15</accession>
    <name>A0A518IZ15_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AsmA_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_43510</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032712">
        <property type="entry name" value="AsmA_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13502">
        <property type="entry name" value="AsmA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AsmA_2" evidence="2">
        <location>
            <begin position="851"/>
            <end position="1002"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1057"/>
            <end position="1078"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1078" mass="119935" checksum="428BDB0B2C1B1B0B" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZC3</accession>
    <name>A0A518IZC3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_44660</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="5"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="115" mass="12940" checksum="C363ED72E5157667" modified="2019-10-16" version="1">MWGRVVEIMTAAWMVFSPFIFAGDHSETLLILNSFTALLIASLAALSYWPPTRYAHLGILIVATGMLIWGRFAELPPPPFQQNYIVVGLFLMMIAIIPNEASDPPRVWRKEVDHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZC6</accession>
    <name>A0A518IZC6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FeS cluster assembly protein SufB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">sufB_2</name>
        <name evidence="3" type="ORF">Mal33_44520</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0051 (ycf24) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010231">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000825">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037284">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045595">
        <property type="entry name" value="SufBD_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01458">
        <property type="entry name" value="SUFBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19295">
        <property type="entry name" value="SufBD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101960">
        <property type="entry name" value="SSF101960"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01980">
        <property type="entry name" value="sufB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SufBD_N" evidence="2">
        <location>
            <begin position="137"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="468" mass="52341" checksum="1F0BC910E6E6FD78" modified="2019-10-16" version="1">MAIDIADNSEIGEINKYNFRTETTGVFKAQKGINEAIVRQISEIKNEPKWMLDFRLKSLKTFEERPMPKWGGAIDIDFQDIFYYLKPTDHQGKTWDDVPQEIKDTFEKLGIPEAERKFLSGVKAQFESEVIYGSLEEDLAKQGVIFTDTDTAVREHPDLVREYFGKIIPPEDNKFAALNSAVWSGGSFIYVPPGVKIDFPLQAYFRINAENMGQFERTLIIVDEGASIHYVEGCTAPMYSSESLHSAVVEVIVKRGARARYTTIQNWANNIYNLVTKRAYAYGDATMEWVDGNLGSKLTMKYPAVHMMEPGARGEILSIAFSGAGQHQDAGAKLVHAAPHTTGQIISKSISKNGGRSSYRGLVRVEKGAHHSKNNVVCDALILDDISRSDTYPYIEILEQDVSIGHEASVSRIGEEQLFYLLSRGLTEQEASAMIVNGFIEPLVKELPMEYAVEMNKLIQLQMEGSVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZE3</accession>
    <name>A0A518IZE3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">dTTP/UTP pyrophosphatase</fullName>
            <shortName evidence="2">dTTPase/UTPase</shortName>
            <ecNumber evidence="2">3.6.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Nucleoside triphosphate pyrophosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">Nucleotide pyrophosphatase</fullName>
            <shortName evidence="2">Nucleotide PPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">yhdE</name>
        <name evidence="3" type="ORF">Mal33_44830</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>H2O + UTP = diphosphate + H(+) + UMP</text>
            <dbReference type="Rhea" id="RHEA:29395"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="EC" id="3.6.1.9"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>dTTP + H2O = diphosphate + dTMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:28534"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37568"/>
            <dbReference type="ChEBI" id="CHEBI:63528"/>
            <dbReference type="EC" id="3.6.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Maf family. YhdE subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.9" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036218">
        <property type="term" value="F:dTTP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035529">
        <property type="term" value="F:NADH pyrophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036221">
        <property type="term" value="F:UTP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009117">
        <property type="term" value="P:nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00555">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00528">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029001">
        <property type="entry name" value="ITPase-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003697">
        <property type="entry name" value="Maf-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43213">
        <property type="entry name" value="PTHR43213"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02545">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006305">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52972">
        <property type="entry name" value="SSF52972"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00172">
        <property type="entry name" value="maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="81"/>
        </location>
    </feature>
    <feature type="site" description="Important for substrate specificity" evidence="2">
        <location>
            <position position="22"/>
        </location>
    </feature>
    <feature type="site" description="Important for substrate specificity" evidence="2">
        <location>
            <position position="82"/>
        </location>
    </feature>
    <feature type="site" description="Important for substrate specificity" evidence="2">
        <location>
            <position position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="221" mass="23905" checksum="0E38F8C9E8F70D21" modified="2019-10-16" version="1">MPESPPQQAAFSRIVLASGSPRRRELLEQAGYAFDVIPADPSVECGVCSSETPAELVARHAFRKAEDVSRQVDAGMVIAADTVAACRGQILGKPEDREHARQMLRMLAGTNHAVFTGVCLWSLPDQRASLDVCCTQLQMEAIDDATIEAYLDSDRWVGKAGAFGYQDGNDWLQILSGSPSNVVGLPMERLQEMLASFAETAQAIDVSARQAPLVEIDRPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZH8</accession>
    <name>A0A518IZH8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_45210</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="350"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="46"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="353"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="371" mass="41894" checksum="C9F3BF965DB6D451" modified="2019-10-16" version="1">MRRPAEDDDDGGLDSLLDTMTNVVGILVLVLIVTQMSVTEVVTRIRSETVVDAEKLEQAKKELAEKEDEKNELERILVAPQDIDADKQKEELQKLKDLLARQKKAREDAKKEQEQYALKIEQQQKAAEEAKKKIAETTGKREELTKLISTSLDRKAQIEAMLDKTPIRARPADIKVSIPNPRPAPPGAKQASFLCSGNAVYPINVEAFRERAAKIAKAIVARGNMNRDPQVGIDPEKFTAIFAGEKKDQDAFFDVEYYVQSNRYPRMRFHPREKRGAVATALLNKRSVIRRDYLANLDVTKYYARFYVLPDSFDIYLTARGIFQDAGMLAGWDPQPQDWLYTTHVGGVELGPPLPKNPNPPPPRKPQSVID</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZM6</accession>
    <name>A0A518IZM6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Orotidine 5'-phosphate decarboxylase</fullName>
            <ecNumber evidence="7">4.1.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">OMP decarboxylase</fullName>
            <shortName evidence="7">OMPDCase</shortName>
            <shortName evidence="7">OMPdecase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">pyrF</name>
        <name evidence="9" type="ORF">Mal33_45620</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>H(+) + orotidine 5'-phosphate = CO2 + UMP</text>
            <dbReference type="Rhea" id="RHEA:11596"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57538"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="EC" id="4.1.1.23"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the OMP decarboxylase family. Type 2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.23" evidence="7"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004590">
        <property type="term" value="F:orotidine-5'-phosphate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01215">
        <property type="entry name" value="OMPdecase_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018089">
        <property type="entry name" value="OMPdecase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011995">
        <property type="entry name" value="OMPdecase_type-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001754">
        <property type="entry name" value="OMPdeCOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43375">
        <property type="entry name" value="PTHR43375"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00215">
        <property type="entry name" value="OMPdecase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00934">
        <property type="entry name" value="OMPdecase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02127">
        <property type="entry name" value="pyrF_sub2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00156">
        <property type="entry name" value="OMPDECASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="6 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 7" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OMPdecase" evidence="8">
        <location>
            <begin position="22"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV58539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="303" mass="32089" checksum="092DE51B00C66C1D" modified="2019-10-16" version="1">MMSDNAAFGDRLAQAVTDKKSVVCVGLDPRFEQLPSGLRDAAAASPQGRAAAFSQFCREIIDVVAPLVPVVKPQAAFFEQLGPHGTMALAETIEYAHRKGLMVILDGKRNDIGSTAAAYASAYLGAGDRSAWGSDALTVSPYLGADSIEPFVETCDSRQAGIFVLVKTSNPGGGLLQDRRSEDGSVYEAVANLVTQQNADRLGTSGYGPVGAVVGATYPEQLAELRQRMPSAWILIPGFGAQGGSAADVAAGFDDKGLGAIVNNSRHIIFAHARPEFKESFGDARWQQAVEAATRQMNEQLKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZN3</accession>
    <name>A0A518IZN3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Endonuclease/Exonuclease/phosphatase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_45180</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="SSF56219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="3" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022014489" evidence="1">
        <location>
            <begin position="19"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="domain" description="Endo/exonuclease/phosphatase" evidence="2">
        <location>
            <begin position="28"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="336" mass="38322" checksum="0F56393312D30A11" modified="2019-10-16" version="1" precursor="true">MHRLLCVLLCFQAVAAYADESADDFVVMSWNLEWFFDSQPRDNRSDLAREMSAPDRPNWDWRRDAVAASIASVRPDVVALQEVESSKVMGYLTTTLEDDHDQKFRFVCFDGAEPFTEQDVALLYADNVWLRRSGLNGQSRKMHASGDYYNVFKHLEAELEIGRPSDPEVVTVINLHLRARAERADIRVRQARLVHTWIADRIAAGENVIVLGDLNTEEPAEGVRDGSDLAILCGKHTPRTDDDLIDLHPRLSVDQRQTHLLAGKAFDRILVSPAMIDDDPDRVDLVLRSVQRPRELSVKGDGPDEQDAHWNAYWQIDSNQRDLSDHWPVVARFQLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZQ6</accession>
    <name>A0A518IZQ6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ribosomal large subunit pseudouridine synthase A</fullName>
            <ecNumber evidence="2">5.4.99.28</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rluA_2</name>
        <name evidence="2" type="ORF">Mal33_45960</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="5.4.99.28" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106029">
        <property type="term" value="F:tRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034470">
        <property type="term" value="P:ncRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001522">
        <property type="term" value="P:pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02869">
        <property type="entry name" value="PseudoU_synth_RluA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PseudoU_synth_2" evidence="1">
        <location>
            <begin position="14"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="226" mass="25510" checksum="BB26CBFCFA9BBC6F" modified="2019-10-16" version="1">MTTLPFPILYEDNHLLVIDKPAGIATQGVTDGTSVFDQASEYIRVKYQKPGKVYLGIVSRLDTVTSGVLVLARTSKAASRLSDMLRRRTIEKRYLAVVEGTLPDAEGMLVDFVRKDDAAHRMVVCRESTADAKRAELRYRVIESSGRQSLIEVELITGRKHQIRLQLASRGMPVIGDRKYDASSTFPQGIALHAWQLTFEHPTRREPMSFECRPPKSWQRLSVQLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZU2</accession>
    <name>A0A518IZU2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Outer membrane protein assembly factor BamB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">bamB_4</name>
        <name evidence="2" type="ORF">Mal33_46330</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018391">
        <property type="entry name" value="PQQ_beta_propeller_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002372">
        <property type="entry name" value="PQQ_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13360">
        <property type="entry name" value="PQQ_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00564">
        <property type="entry name" value="PQQ"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021945986" evidence="1">
        <location>
            <begin position="21"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="438" mass="46118" checksum="506FB51DA3C62A15" modified="2019-10-16" version="1" precursor="true">MSDFHRFSLPLGLLVSFATAIDVVAAPPSWPEFQNGGQAVAAEVNLPTHWAPDQNIAWTADIVGYGQSAPIVAHDQIVVTSTSGENKDDYHVSAYAFASGDLRWQVDLKNPSPFKNTPMVSRAAPTAIATDTGYIAFFEGGALIALSPEGKTLWQKDLVAEYGKIEARHGLSASLEQNNDLVFVWVERGEEPYILAFNKTDGEVVWKAPGVGSTSWASPRLIPVGSSHHLVCSASGKIVGLDPASGDRLWEFSDISNNTSCTPMPVGDGQFLIGASDGRGETAAGAAAASNGLIEISKGEDGKFTAAYKWQAKKATSTFGSPVVAGDTAAIVNRTGVLYRLDLQTGDQVSIARTAAGGIWATPIVAGDRIYLFGNKGTTSVVSLTDGKEIASNRCWDAEAESGEGVRSGSVLYAAAAASPYLVLRRGDKLYAISAGDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZY1</accession>
    <name>A0A518IZY1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Mechanosensitive channel MscK</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">mscK_2</name>
        <name evidence="12" type="ORF">Mal33_46750</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MscS (TC 1.A.23) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011066">
        <property type="entry name" value="MscS_channel_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011014">
        <property type="entry name" value="MscS_channel_TM-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023408">
        <property type="entry name" value="MscS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025692">
        <property type="entry name" value="MscS_IM_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024393">
        <property type="entry name" value="MscS_porin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12795">
        <property type="entry name" value="MscS_porin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12794">
        <property type="entry name" value="MscS_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="SSF50182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82689">
        <property type="entry name" value="SSF82689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82861">
        <property type="entry name" value="SSF82861"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="579"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="620"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="661"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="704"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="733"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="777"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="812"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="877"/>
            <end position="900"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="920"/>
            <end position="942"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="962"/>
            <end position="981"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="993"/>
            <end position="1021"/>
        </location>
    </feature>
    <feature type="domain" description="MscS_porin" evidence="11">
        <location>
            <begin position="132"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="domain" description="MscS_TM" evidence="10">
        <location>
            <begin position="588"/>
            <end position="908"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="97"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="178"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="210"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="310"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="383"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="488"/>
            <end position="515"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF12794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF12795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QDV58651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1201" mass="133604" checksum="D14E233564A1D596" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
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    <name>A0A518J043_9BACT</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
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            <begin position="32"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="111" mass="12025" checksum="A1AE01BC33667905" modified="2019-10-16" version="1">MFLKSIGFVVCATIAAGGLAHLQMQAELPDPVAFLISLVVTPFLWIGGAVTYFCVAGDNYSGEKHFWPYVVPASVLANAVLAVVLLPVVTQLWKSLVLMKKQRNAKLHKGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J085</accession>
    <name>A0A518J085_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Universal stress protein E</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">uspE</name>
        <name evidence="2" type="ORF">Mal33_47760</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
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    </dbReference>
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        <property type="entry name" value="Usp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="4"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="Usp" evidence="1">
        <location>
            <begin position="152"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="320" mass="35207" checksum="1728043993B56EAD" modified="2019-10-16" version="1">MKRFRNILVALDTRSTTHPALDWALSVAVPSKARLTLVDVLPDLSWIARNVVPHSEAHQQLMLDDKQQKLEELAEPIRKQGLDVTTKVLRGKTSRALCDEVFHADHDLLVRVTRGTNSRSSAFYGTTGSRLMRNSPCALALIHPNYAASSGRIVAAIDPARNNSAHYKMTREVLDLTKSLAELQQKEMHVVHAWVLFTPTLLKSTFSANDLANFRKSSEADIAKEVDEVLEPFGLSHRDRRVHLIEGKIEAGDSVAKFADEENVEMIVLGTMARSGIAGALIGNTAERVLELAKCSLLTIKPDAFISPESAADDDNEPGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0B2</accession>
    <name>A0A518J0B2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_47700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="154"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="199"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="226"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="299" mass="33368" checksum="E734DB99887812C5" modified="2019-10-16" version="1" precursor="true">MTPPNRINLPTLCLRLGAFLCFAGWTWVHYYWEGPYGVLLWHDATFEFATGLGLTWEEFVGDGINDGFVQQWIAKLWWLYLACTLLTLTVRQRSWLQMIGLVLGSGLLVVLSYAAYVASQNQLPMFIEHGGQMLSPILLVMALALGVRHRATVITAIVAVILTFAGHGSYALGLWPTPGNFYAMTTLILGVEYPTAQTMLRIAGVLDFVVCIGICIPYLRRPAALYASLWGFLTAIARPVAGMSWGLNYWGADQYLHEAVLRAPHCLIPLYLFLLWRQPPSTDNLDKLEPTDSEPMGNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0L9</accession>
    <name>A0A518J0L9_9BACT</name>
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        <submittedName>
            <fullName evidence="5">tRNA-binding protein YgjH</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ygjH</name>
        <name evidence="5" type="ORF">Mal33_49210</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="CsaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002547">
        <property type="entry name" value="tRNA-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11586:SF37">
        <property type="entry name" value="PTHR11586:SF37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01588">
        <property type="entry name" value="tRNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02222">
        <property type="entry name" value="chap_CsaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50886">
        <property type="entry name" value="TRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1 3" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="TRNA-binding" evidence="4">
        <location>
            <begin position="8"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV58896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="112" mass="12442" checksum="ED7B3F4CB5EF0CB3" modified="2019-10-16" version="1">MNEISWDDFQRVELRVGTIVAAEEFPQARKPAYKLRVDFGPEIGIRRSSAQITDLYSPDQLVGRQVIGVVNFPAKQIGPMMSECLITGFHRDDGSVVLAVPDQQVDNGVRLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0U3</accession>
    <name>A0A518J0U3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_49770</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="85" mass="9355" checksum="2CE78E5E59011B14" modified="2019-10-16" version="1">MQIAKNASGSDPMACDLNNTASEWLIEQTEINSVVNQRELNLGCGGNSQKHGVDVKPAESRCRKTQRFTLPAPSIEFNPVRNAIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J152</accession>
    <name>A0A518J152_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FecR protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_50830</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006860">
        <property type="entry name" value="FecR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012373">
        <property type="entry name" value="Ferrdict_sens_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30273">
        <property type="entry name" value="PTHR30273"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04773">
        <property type="entry name" value="FecR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="FecR" evidence="2">
        <location>
            <begin position="178"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV59058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="463" mass="49923" checksum="73E067099B63E683" modified="2019-10-16" version="1">MNSSSDLQTLIADYAAGVIAPADLRKLETALRSNVELRRDFIEYMNLDSAISDRAALSDAEFDAIRCEHTAALEIVPVAKRSPWRNLGVIIGVAAVMLFIMGIVRFKSTIKSAAPIAAVAAEIMSLDGAELDGIDQEVRVGNRLSLNRIRLETGAIQLRLDNGVVLDMTGPLDGTLESSMRLRLAHGRLNADVDEAGQGFTIVTEHGEITDLGTRFGVEVSRNEASIAVFDGQVNVASHGDDSGRPLKVLEGEGVRLRKGRRPQRLSAVWLSQGGYSLSASAGASIVVDVTDNAKPDGLHRFYGIVSDGMRAGTIAYTTHASTPRPDVVWQAAEGEAFPAELLGADVVCPFHVDRQEQSLTISLRLAGAANVYVMHDQRRNPSAWLANGFQKTELTLRSGPWRSVSPLAEGIEPDRDGEIYVQYSVWKKRVDAAGSIKLGPPQTDGDRGNKAMYGIAVKAIPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J170</accession>
    <name>A0A518J170_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_51140</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.720.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018668">
        <property type="entry name" value="DNA-binding_VF530-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036361">
        <property type="entry name" value="SAP_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09905">
        <property type="entry name" value="VF530"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="101" mass="11670" checksum="13E3F63A762D4744" modified="2019-10-16" version="1">MDSSQPNNPLHGITLKAILEYLVAEYGWERLGDRIQIRCFQSDPSISSSLKFLRKTEWARTKVERLYVNSISYDQRKGKKSEPAQSVPAPTESVWDRARRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1I0</accession>
    <name>A0A518J1I0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">dTDP-glucose 4,6-dehydratase</fullName>
            <ecNumber evidence="4 5">4.2.1.46</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rffG</name>
        <name evidence="7" type="ORF">Mal33_52210</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>dTDP-alpha-D-glucose = dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H2O</text>
            <dbReference type="Rhea" id="RHEA:17221"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57477"/>
            <dbReference type="ChEBI" id="CHEBI:57649"/>
            <dbReference type="EC" id="4.2.1.46"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 5">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 5">Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.46" evidence="4 5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008460">
        <property type="term" value="F:dTDP-glucose 4,6-dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009225">
        <property type="term" value="P:nucleotide-sugar metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05246">
        <property type="entry name" value="dTDP_GD_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005888">
        <property type="entry name" value="dTDP_Gluc_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01181">
        <property type="entry name" value="dTDP_gluc_dehyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="6">
        <location>
            <begin position="4"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV59193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="352" mass="39840" checksum="B962FAECE273D693" modified="2019-10-16" version="1">MKILITGGAGFIGSNLVRHLLAETDHEVVNLDKLTYAGNLASLTDIQSNPRYRFTQVDLCDAEAVKNVFHEHDPDRVMHLAAESHVDRSIDSPGDFIQTNVVGTYNLLHASLHHYQQLDTPRRDSFRFLHVSTDEVFGSLGMDDPGFNETTPYDPHSPYSASKASSDHLARAWHDTFGLPVLVTNCSNNYGPYQFPEKLIPVVILKCLRGEPIPVYGAGANVRDWLYVEDHCRALTRVLDAGTVGETYNIGGNNERSNLDLVKMLCGLLDEMHPSSDGKRYEENIQFVTDRPGHDMRYAIDATKIGRELDWQPAEDFDSGFRKTVRWYLENQTWWQNILSGDYRLERLGEKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1P6</accession>
    <name>A0A518J1P6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_52950</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021967531" evidence="1">
        <location>
            <begin position="22"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="191" mass="19064" checksum="70CEBB04D93234EE" modified="2019-10-16" version="1" precursor="true">MLNKFKSFELVAGALTLVSLAAIGCASRGGFLGVDCCADIPAGAIPEPAGAKLCDWQTAQVTSAVADQTVFYQSDFIGTSATLSPAAIDRMARNANSGLVFSQPSIVEPSGNDLRDAARVESVIAQLASLGVAAPVVEVATPAALGMQGQLAERVGGGFGNPIAGTGAPISQASGFGGQSVGMNVTGGMFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1Q4</accession>
    <name>A0A518J1Q4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_52910</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021992232" evidence="2">
        <location>
            <begin position="19"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="184"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV59263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="451" mass="49279" checksum="DC1C06D526C606AE" modified="2019-10-16" version="1" precursor="true">MFRYCALLCLLLTSGVTAAEPDQLRLATFAADITIPLGHRCMGVLPIKAQRIEDPLEARGLVLLGSGKPVVIVALDWCEVRNGAYDQWRDQLATAAKTDRNRVMVCSLHQHDAPVTDSGAQALLDSVGMQGELYDVAFHADCIARVSDAVRTAIASAQPLTHVAASEAKVAQIASNRRVEYPDGRVGYNRGSRMDPKSAEAESDAGEIDPFLKSIHFYNGDRELATLTSYATHPMSYYGRGGVTADFVGMARRRRQLDTEGSMQIYLTGCSGDVTAGKYNDGAPATRGILADRLYRAMVEAAAAAKRQSITEYDFRCGELQLPFHEGEEFTEEAMTAVLQDDTASEKARILAAMGLSSLERLETQPIDLPCLDLGIAQIVLLPGEAFVGYQLMAQRLRPDSFVMAVGFGESWTGYIPTKRAFDEGFGHSWRWVGRGSEAVIREQLTRVLAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1R2</accession>
    <name>A0A518J1R2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Type II secretion system protein D</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">pulD_2</name>
        <name evidence="5" type="ORF">Mal33_52960</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial secretin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001775">
        <property type="entry name" value="GspD/PilQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032789">
        <property type="entry name" value="T2SS-T3SS_pil_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004846">
        <property type="entry name" value="T2SS/T3SS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00263">
        <property type="entry name" value="Secretin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13629">
        <property type="entry name" value="T2SS-T3SS_pil_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00811">
        <property type="entry name" value="BCTERIALGSPD"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021915665" evidence="3">
        <location>
            <begin position="34"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="domain" description="T2SS-T3SS_pil_N" evidence="4">
        <location>
            <begin position="125"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="69"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="636"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="71"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="669"/>
            <end position="683"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU004003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV59268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="689" mass="74404" checksum="C82E77E0951D4C48" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1T0</accession>
    <name>A0A518J1T0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Heme chaperone HemW</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_53250</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004109">
        <property type="term" value="F:coproporphyrinogen oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006779">
        <property type="term" value="P:porphyrin-containing compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034505">
        <property type="entry name" value="Coproporphyrinogen-III_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010723">
        <property type="entry name" value="HemN_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004559">
        <property type="entry name" value="HemW-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023404">
        <property type="entry name" value="rSAM_horseshoe"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13932">
        <property type="entry name" value="PTHR13932"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06969">
        <property type="entry name" value="HemN_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00562">
        <property type="entry name" value="HemN-like__clustered_with_heat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00539">
        <property type="entry name" value="hemN_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="3">
        <location>
            <begin position="15"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU364116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV59297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="389" mass="43218" checksum="F80A75C429F54854" modified="2019-10-16" version="1">MVIRNQTDLELEAPARLDPPRAAYVHVPFCQHRCGYCNFSVLAGRDDLVDAYLDALEAELKRLVQPRTVDTLFVGGGTPTHFDAPALTRFLRLVGHWFPLSGGATEFSVEANPNDITQSKLDLLKQFGVDRISLGVQSFDAAKLKILERTHSPDEARRAIQLAAETIGNVSIDLIFATPGETPDAWRGDLRDAVAMPLSHLSTYGLTFEKGTQFWNRLQKATIATVIEEDQLQMFRDAIAIPKAAGFEHYEVSNHAMPGRRCQHNMAYWRGVGWYAAGPGAAAFVDGRREVNHRSTTTYIKRLLRGESPIAESETLTQEQLIRERVAFGLRMLAGVELTEVGPLQVIDQLLGKQFQMLTEIGMLTRTDNRIALTAQGLFVSDSVLSEIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1U8</accession>
    <name>A0A518J1U8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Teichoic acids export ATP-binding protein TagH</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">tagH</name>
        <name evidence="6" type="ORF">Mal33_53400</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03220">
        <property type="entry name" value="ABC_KpsT_Wzt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10147">
        <property type="entry name" value="Wzt_C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015860">
        <property type="entry name" value="ABC_transpr_TagH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029439">
        <property type="entry name" value="Wzt_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14524">
        <property type="entry name" value="Wzt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="49"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="83"/>
            <end position="90"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV59312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="428" mass="46072" checksum="C5E4D52CAC416D86" modified="2019-10-16" version="1">MKKQIIQVENLGKSYFVGHQSADSERYTALRDVIGLQIKKLARNASDMARGKQIIQGDNIEEFWALKDVSFDVAPGEVVGIIGRNGAGKSTLLKVLSRITEPTQGRARLCGRVASLLEVGTGFHPELTGRENVFLNGAILGMGRSEIKRKFDEIVDFAEVEKFLDTPVKRYSSGMYVRLAFSVAAHLEPEILVVDEVLAVGDIQFQRKCLGKMGQVASGGRTILFVSHNMSAVENLCSRGVVLNQGSITFDGNTKDAIATYGSKAASSSNSLPPIESRQGNGTARVTAVQCPASVSSGVQFDIGIKFEVYDATKSPDVRISIYSHSGHCIANFGTSYTSTPFGMVLGEASALLRIPNLALNVGHYTVNVSISDPSYSSDVICDRIEEAARFEIVTADPFGTGKHPAVGSVLMPHTWLLAPPTQIGIDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J208</accession>
    <name>A0A518J208_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_54010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="458" mass="50183" checksum="2980F70C2DFC913B" modified="2019-10-16" version="1">MVNLHPSAANNFHWQPQPDAWRCIARIVQTLAADEPYIQDLAVRMLSETGTRLIDWVAEIRLPFGSPEVDNLLAAGFVDAGDPQRKLLVNRDGMFPVVHLQAESSKPCLVIKVERLADFCTANGGSNWEQAKEQGNGFLSCTAVVHEGAKCDLAAVENHGSTPQQPVTQLAEHVAAFRTAVAGRSRPVARVDAGAAFDATIALFRDAVAKLGTGLACDLFFQLEREYWQDRNLAARLQKQRQDALGLGWGNHDHHTYRSSRAGFHRLIEALEVLGFVCRERFYAGADAGWGAQVLEQAEAGVIVFADVDLSPDEVAGDFAHQPLEDRAELGTVGLWCRLHGEAFLAAGMHHLECQFDFDAARAQLALLGIATMEPFTDFPFLRQAFTAAETWAVDPDVLREAVADRAITAAEAERFEKQGASGSHLEILERNDGYKGFNQTGISDIIQRTDPRNSSAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J222</accession>
    <name>A0A518J222_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Planctomycete cytochrome C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Mal33_54060</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011429">
        <property type="entry name" value="Cyt_c_Planctomycete-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011444">
        <property type="entry name" value="DUF1549"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022655">
        <property type="entry name" value="DUF1553"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07635">
        <property type="entry name" value="PSCyt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07583">
        <property type="entry name" value="PSCyt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07587">
        <property type="entry name" value="PSD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021756538" evidence="2">
        <location>
            <begin position="25"/>
            <end position="1032"/>
        </location>
    </feature>
    <feature type="domain" description="PSCyt1" evidence="5">
        <location>
            <begin position="45"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="PSCyt2" evidence="3">
        <location>
            <begin position="159"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="domain" description="PSD1" evidence="4">
        <location>
            <begin position="728"/>
            <end position="977"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="392"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV59378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1032" mass="116437" checksum="CC89EDC007EF670B" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J262</accession>
    <name>A0A518J262_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peptidoglycan deacetylase</fullName>
            <ecNumber evidence="2">3.5.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">pgdA</name>
        <name evidence="2" type="ORF">Mal33_54510</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.5.1.-" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="SSF88713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NodB homology" evidence="1">
        <location>
            <begin position="53"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="346" mass="39010" checksum="57AD9D12A391E274" modified="2019-10-16" version="1">MLAIVIMLGLLVGESPADERFHFPVAIPPMSPPIADLSLDLDNLWAYLRTHGDAQWETFPSYLPTVVPHFLEIFDRLNLRATVFVVGQDAALEKNHGPLRQIVDAGHEIGNHSFNHEPWLQRYSREQLVDEFEQTEAALAKITDQAIVGFRGPGFSLSADVLQLLCQRGYQFDGSTFPTFLGPMARAYYLMTSTFSSAEKEDRSEMFGSLRDGLRPLKPYWWTTPSGRVLELPVSTIPIVRAPFHFSYLCFLAQVSPRLAELYFRIALAICRLTRTSPSLLLHPLDFLGGDEVPQLSFFPGMKLTGDVKRAFSERMLAIYAKQFEVLPMGEHAVRIGTKVTNSRTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J286</accession>
    <name>A0A518J286_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_54760</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="63" mass="7014" checksum="3CBCC81431DA239B" modified="2019-10-16" version="1">MRSVRCRNDGVNRRSNCRNFGGTDTGGYPHGKMMEKNFHPGGEAPPSGALPNERVVQRDSRVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J2B7</accession>
    <name>A0A518J2B7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Soluble pyridine nucleotide transhydrogenase</fullName>
            <ecNumber evidence="5">1.6.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">sthA</name>
        <name evidence="5" type="ORF">Mal33_55190</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="2">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <dbReference type="EC" id="1.6.1.1" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003957">
        <property type="term" value="F:NAD(P)+ transhydrogenase (B-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001100">
        <property type="entry name" value="Pyr_nuc-diS_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000350">
        <property type="entry name" value="Mercury_reductase_MerA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="SSF55424"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="4">
        <location>
            <begin position="8"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="domain" description="Pyr_redox_dim" evidence="3">
        <location>
            <begin position="347"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="182"/>
            <end position="189"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="269"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="310"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV59484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="467" mass="51001" checksum="EFE9FDCDA0CB5D97" modified="2019-10-16" version="1">MSNSTYDYDVLVIGTGPGGEGAAMQAAKAGLRVAVVERHTSIGGGCTHWGTIPSKALRYSISSVMNALGSPVLRACGVHANPTMKQLRSSAQQIIGKQVSMRQTFYDRNNVPVLVGQASFVDDHTIRIDGQSDQKVTANKIVIAVGSRPYHPPDVDFEHPRIFDSDTILGIDEKPFSITIYGAGVIGCEYASMFRNLGIKVNLINTRAKLLEFLDDEIIDALAYHMRDQGVVIRHNETLDKIEGVDDGVILHLKSGKQLKSDALLWANGRQGNTDGLGLENVGLTPDKRGQLEVDEQFQTARDHIYAVGDVIGFPSLASAAYTQGRAAARHFSDSVEVESNLRIRDIPTGIYTSPEISSVGKTERELTEECVPYEVGSSQFKSLARAQITGRTAGMLKILFHRETREVLGVHCFGAEASEIIHIGQAIMNQPAGHNTIDYFVDTTFNYPTMAEAYRVAALNGYNRLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ILZ8</accession>
    <name>A0A518ILZ8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_00450</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="130" mass="14965" checksum="7D9F9065B5A7AD54" modified="2019-10-16" version="1">MFEAFRLIPALQAIFQSGIEFREDSFAELNAAQREAYERKVAVPDEPIFRVLPCEPTVIERQGNEKVTVELTIATQSERQLLLEAVRFIYRATDELPKESTSFEQRLDFLRQRLPPIVVGEPDLDRPEGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IM07</accession>
    <name>A0A518IM07_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator SlyA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">slyA_1</name>
        <name evidence="2" type="ORF">Mal33_00560</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023187">
        <property type="entry name" value="Tscrpt_reg_MarR-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01047">
        <property type="entry name" value="MarR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01117">
        <property type="entry name" value="HTH_MARR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="20"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="160" mass="18516" checksum="DE9B99A2364E5B1C" modified="2019-10-16" version="1">MSSSQLQKELKKKRPFESPEQEAILNLLRTNDQFQNRFGRLFREYGLTSSQYNVLRILRGEGNPLPSLEIAERMIQVVPAITGLIDRLEKQGLVTRKRCLEDRRVIYIEITDSALALLKQIDEPLLSLHKRLIGHLNRTELKELSRLLEKARLSLPGLDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMK0</accession>
    <name>A0A518IMK0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">HIRAN domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_02680</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016818">
        <property type="term" value="F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014905">
        <property type="entry name" value="HIRAN"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08797">
        <property type="entry name" value="HIRAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00910">
        <property type="entry name" value="HIRAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HIRAN" evidence="3">
        <location>
            <begin position="135"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV54318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="255" mass="29072" checksum="F33BFD5AC9711BB6" modified="2019-10-16" version="1">MTPPNQTVFVAWHAEQPMPRWAAVARLDCLYSELGDRRFRFSYTEGARTIEGFRPLDGMEDLHQVYESTSLFPVFKNRLLPASRPEFRQFLEWNGFDPDDPPEPLLLLGRSEGIRKTDAIEVFPKPVPDSHGCFVNFFFVHGIRFQPTAAERISHLHPGDSLTVRQEPENPIDPHAIALEANGSMLGYTPRYLARDIERLLSQCPAETVRVVVQQVNLDAPLQQRLLCRMNACWPAGFQPCDTVDYQPISSLVPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMN8</accession>
    <name>A0A518IMN8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Inner membrane transport protein YbaT</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ybaT</name>
        <name evidence="6" type="ORF">Mal33_03150</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="41"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="81"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="128"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="156"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="185"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="223"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="274"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="322"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="345"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="374"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="405"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV54361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="445" mass="46728" checksum="F4DEA241456F7A43" modified="2019-10-16" version="1">MSSTSEPKLGTFSTLSIGIGGMVGGGIFAVTGLTITATQGAAPIAFLIAGIVALLTSYSYLKLTLRYPGVGGTVDFLNRAFGTGIFTGAANILLLLSYVVLVAVYAYAFGSYGACFFPEPDRPFWTHALISGVIVGLVGVNALGGSLVVRAENVFNIVKILLLAAFIVAGLATPMEWSRLGTEHYVSPMGLVAGAMLIFLNYEGFELIANASKDVANPKRSLPIAYVGGVLIVIVIYMLIVAVVVGHLSFAEVAKDSDTALSVAAQDVMGRTGYIAIAIAALLATSSAINATFYSTGRLAYIIAKTGELPSELKRSFRGQHLEGTLITAVLALVVANFVPLDAIATMGSAGFLLLFLAVNVANVRLARQTNSRAWLSGLAALSTLVAMIVLCVKVDENPATRNHLWILVGMIVVSLTIEIVYRSLTGREVRMGRTPDSNPKSDVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMZ0</accession>
    <name>A0A518IMZ0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_04090</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010869">
        <property type="entry name" value="DUF1501"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07394">
        <property type="entry name" value="DUF1501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="469" mass="51603" checksum="FC0923E8F4D9B3EE" modified="2019-10-16" version="1">MNVHPQINDSRRSFLYQLGASLGSVALTNLLASEAAAAAGPLSPKPPMMPAKAKNVIMLFMEGGPGHMDTFDPKPELTRLHKKESKLKAGQEAGFKFFVGSPFGFQKVGQSGIEMCDQWKHLADPYVADELCNYRGCQAESLNHPEALFHMNTGSRLGGDPGLGAWATYGLGSENENLPGYVVMTELALPQGGAGNWTNGFLPPYYQGTRLRPTGSPILDLASQEFKSREHQRRALDELAQLNQSHLESLGAEDQRLRARMESYELAFRMQTEVPGVIDLSKETQQTLDMYGLNAPETETFGRQCLMARRLVESGVRFVQIFSGGWDSHDYLERGHTSRIKSVDRPMAALIRDLKQRGMLEDTLIIWTGEFGRTPDNNKRGGVYSLGRGHNNNAMTMLMAGGGVKRGAIVGATDELGASAVECVHPIRDLHVTLMHLLGLDDNKLTYLHAGRYKQLSQFGGEVIKELIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IN12</accession>
    <name>A0A518IN12_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_04160</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.600">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1610">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010621">
        <property type="entry name" value="DUF1214"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037049">
        <property type="entry name" value="DUF1214_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010679">
        <property type="entry name" value="DUF1254"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037050">
        <property type="entry name" value="DUF1254_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06742">
        <property type="entry name" value="DUF1214"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06863">
        <property type="entry name" value="DUF1254"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1254" evidence="2">
        <location>
            <begin position="106"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1214" evidence="1">
        <location>
            <begin position="420"/>
            <end position="529"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="546" mass="59237" checksum="E72A37201D513FB6" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IN28</accession>
    <name>A0A518IN28_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_04450</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022058511" evidence="2">
        <location>
            <begin position="28"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="389" mass="42802" checksum="442A96597C6555F1" modified="2019-10-16" version="1" precursor="true">MFQKTLNASLTIALAIGFATSARSLNAQVTPPPTTGGLSTPPSMQRAPATTAATSVSGQLPRDANQEFRQYDLSRYTNNLSKIDKPEQAVVDWVLRETGTDVWFSEPFGFLSTNRNMLTAYHTPEMQAVVKKMVDRFVNGPTDPQILKMRLLTVSSPNWRARALPLIQDVNVQSPGVQAWLLTKENAAVLISMLSSRTDARESQNSQMTIYNGQTQSLSSTKGRTYVRTIRQASTVWPPYEPEISEVHEGYQLEISPLLDTDGKTIECVIRAQIDQVDKLVPVGIDLPLPNGQSHRTQIEVPQIVSWRLHERFRWDSDMVLLLSCGVIASPDRQTSSNPLLNLDRFIGNTPGRADALLFITFGGRAGEGLAPAPAPQAAVAGSISRGRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IN51</accession>
    <name>A0A518IN51_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Tetratricopeptide repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_04690</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="35"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="137"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="305" mass="34182" checksum="31488B287DFFC10C" modified="2019-10-16" version="1">MRLRTAILLIFLCLGLAPGCRAIRRTVDSRQSIEARRMSREGLAAIHQNRWEEAEKLFEAALELSRSDDRAYWGYSEVLWQKGQHAEAISHLEQAVRLSAGAPELRVRLGNMYLEEDRVDDAATQVAHVLESTRDMATAWALHGDILVRQEKLEAALASYHRAISLDRQSPQVRLAIADIYSRQQRHDRLLATVDQLEESTIPTEQAAQLEMMRGIAMRELGHPDSGAQHLQRAIALGMSGREVYHELAKTELASRRFAAASHAIRNALQLAPDDAESLSLAQNIQQAQARLAADTANDDLTQER</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IN76</accession>
    <name>A0A518IN76_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_04890</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011453">
        <property type="entry name" value="DUF1559"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07596">
        <property type="entry name" value="SBP_bac_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="60"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="290"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="310" mass="33078" checksum="CB3F0E1A12FBE461" modified="2019-10-16" version="1">MPLLFTCPHCQTQTLVETQYAGQAGACAACGKPITVPDFQEETGSIAMEPRKSIGRPIRLIATICVAAVVVLAGGMLMFRYGVSGIAQIRANSLRGACRNNVRLIAAALNAYADDYGTYPTPMVTDAAGKPMYSWRVLILPYLGHQSLYDQFNLAEPWSSETNMALAYSRPAEYGSPAVGSNVWSEPNYMLITGPGTLFPASGPLSPRDVIDRPDQTLLVVEVARPANPMAGNELLWTQPADLDVAKMVPAINGKDGVEIGGNHEGGATAATSDGRDHFLSESLSAGEIRGLITPRGGEPLPDDLLDDWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INH8</accession>
    <name>A0A518INH8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Planctomycete cytochrome C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Mal33_05900</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011429">
        <property type="entry name" value="Cyt_c_Planctomycete-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011444">
        <property type="entry name" value="DUF1549"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022655">
        <property type="entry name" value="DUF1553"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07635">
        <property type="entry name" value="PSCyt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07583">
        <property type="entry name" value="PSCyt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07587">
        <property type="entry name" value="PSD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome c" evidence="5">
        <location>
            <begin position="37"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV54635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1036" mass="114224" checksum="741C3EFA908F87C7" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INS1</accession>
    <name>A0A518INS1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">tRNA nucleotidyltransferase/poly(A) polymerase</fullName>
            <ecNumber evidence="6">2.7.7.19</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Mal33_07030</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.19" evidence="6"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="F:polynucleotide adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
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        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031123">
        <property type="term" value="P:RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd05398">
        <property type="entry name" value="NT_ClassII-CCAase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002646">
        <property type="entry name" value="PolA_pol_head_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032828">
        <property type="entry name" value="PolyA_RNA-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01743">
        <property type="entry name" value="PolyA_pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12627">
        <property type="entry name" value="PolyA_pol_RNAbd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1 3 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PolyA_pol" evidence="4">
        <location>
            <begin position="29"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="PolyA_pol_RNAbd" evidence="5">
        <location>
            <begin position="182"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF12627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV54743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="438" mass="47703" checksum="A6EDEE640CB6E041" modified="2019-10-16" version="1">MTDSDQPLDPRERFARSVVQKLTDAGHIAYFAGGCVRDRILGLRPKDFDVATDATPDRIRELFGRRRTLAIGAAFGVVSVLGRKGAGEDPIEVATFRSDGDYSDGRRPDSVVFSSPEHDAQRRDFTINGLFYDPIAGRVIDFVDGRSDLQAGVLRAIGDPDARICEDKLRMLRAVRMATVFGFAIESATRDALHRHAAEIDVVSNERVGAEMRRLLAATAAFDGLATLRETRISDVVFPQLAEIWDAEIRQADLPAEIAAPATTGAGLMSKLFVARRECDFVSGLIGCLLAIKWSDGDAGDALRRLADLWRLSNEETARAAFALESLPTVLQADRQPWSIVQPVLAARYAGDAVTLAETVTRALDLPGEAVAAARQRLGWDRDRLDPPALLSGNTLQKLGLTPGPGFREILHDVRARQLDGLLNDAQAAAQYVSATYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INS5</accession>
    <name>A0A518INS5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_07010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="255" mass="29120" checksum="DA237691F64F5EE0" modified="2019-10-16" version="1">MLLGKSAHEKTSVAKFGNRGSSIVVLFKDSLSYRRASRTQIGFPSRLVQFNFKRPVDLATEAYHAVNVWSTQVASFWSGWSRVRRRSSVCSGLWSWSWSSRCSFFNDYWSAFDNSTRARSTCWCSFDDNCAATARASARSNRSATAAWCWCFAASRCWSFAASWCWSFAADWSWSFAAAQFFNHFAASWCWRAALVLLLVACFCRCAECDDHCKYSNAANDSTRHSEISKQSLWVPNANRSNRTCRSPIRLTWFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INW1</accession>
    <name>A0A518INW1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">VanZ like family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_07480</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006976">
        <property type="entry name" value="VanZ-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04892">
        <property type="entry name" value="VanZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="18"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="VanZ" evidence="2">
        <location>
            <begin position="42"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="131" mass="14265" checksum="B0A11DFE24178E17" modified="2019-10-16" version="1">MNAGPADQRGPGISRWKLVGACCALGAFFVPLPAGSQRLDQLYNFSHLLVFGGLAFMMMQVFVGWGFWRRVAFTLSSVLALGVAIELIQPFFGRRASLHDVINDLIGGVVGISIAAAFRWATLMYRPSDQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INY0</accession>
    <name>A0A518INY0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Arylsulfotransferase (ASST)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_07450</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
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                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
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        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
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            <begin position="22"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="310" mass="34673" checksum="8CFFB9BEDCE54849" modified="2019-10-16" version="1" precursor="true">MRLAFPLAFAFLILTNLSAIAQHRFLANQQNKLVIIDAEGKPQWQMMLSGSPHDLQLLDNGNILTHQNTEIIEIDPRSSEIVWSLDAKKFATVDRVEVHSVRAIPGDRIMIALSGEGKLLEVDRDGTLHHSITLQRTHPHPHRDTRLVRRLENGNYLVAQEGDGKVCEYDRDGKIVWQYDVPMFGRKARGGHGPEAFGNSVFSALRLPNGNTLIGTGNGHSILEVTPEKEIVWKLQQHDLPGITLAWVTTLEYHPNGNIVFGNCHAGPENPQLIEINRGQEVLWKVHDFKTLGNDVSNSIILDADANVIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP18</accession>
    <name>A0A518IP18_9BACT</name>
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        <submittedName>
            <fullName evidence="3">Serine/threonine-protein kinase pkn1</fullName>
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        </submittedName>
    </protein>
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        <name evidence="3" type="primary">pkn1_1</name>
        <name evidence="3" type="ORF">Mal33_07850</name>
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        <name type="scientific">Rosistilla oblonga</name>
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        <lineage>
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            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
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    </dbReference>
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    <keyword evidence="3" id="KW-0808">Transferase</keyword>
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            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021788080" evidence="1">
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            <end position="412"/>
        </location>
    </feature>
    <feature type="domain" description="FGE-sulfatase" evidence="2">
        <location>
            <begin position="83"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="412" mass="46528" checksum="820F3C08DBE5FD5B" modified="2019-10-16" version="1" precursor="true">MQSNSVLHESSSRRNDLHMNLYARSLSLCLFALTSCVAIAADDSAKIKGFSTTQPEKGPFVAVEGGFMVPYTETIPGTEISFEMIPVPAGSYKMGSPASEKGHKEDESPQIMVNVDPMWVCKTEVRWIEYKEFMGMYKTFKEFVFRDMRKVTPENKVDAVTTPTELYEPSYTFEFGDDDDLPAVTMTQFAAKQFTKWLSKMTDTQYRIPTEAEWEWAARAGSTTAYSWGESADEIDQYAWYADNSPDGPSKVGLKKPNAFGLNDMLGNVAEWTIDAYLEDGYKVFEGKTVKASEAIKSIETADPRVVRGGSWEMEPEDVRCASRLYSVDEDWKMDDPNIPLSPWWFTSDPSRGVGMRLFRSWKPLSDEAMNKFWEIDSEDIEFDVMSRIEEGRGVLGLADPDLAEAAKAVRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPC5</accession>
    <name>A0A518IPC5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_09120</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021753158" evidence="2">
        <location>
            <begin position="24"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="155"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="155"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="183" mass="19807" checksum="0CD52A989EF786A3" modified="2019-10-16" version="1" precursor="true">MRFLTRLIVLFAATAVLVGGASAQSDPTLNSKWHSKYDSAGGPKNDAMVTLMKSGQDQLGSGKYETQFGNGTFTQVRKQIENRQQTPPIPSTGPLPGPNSPNNGATPNDAVYIKGLWHFAGKTGWFKWELYETPQNECKFLGKWGYVENGQAGPTSGKWNGSLRTGNQNGSPPQKNVPLIAIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPD3</accession>
    <name>A0A518IPD3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Tetratricopeptide repeat protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="4" type="ORF">Mal33_08980</name>
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            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Rosistilla</taxon>
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    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022191451" evidence="3">
        <location>
            <begin position="29"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="195"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="262"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="296"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="476"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="525"/>
            <end position="552"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV54932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="552" mass="61116" checksum="BBB3B5528C25CECD" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPS8</accession>
    <name>A0A518IPS8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_10700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Planctomycetia</taxon>
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            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011453">
        <property type="entry name" value="DUF1559"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07596">
        <property type="entry name" value="SBP_bac_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="328" mass="35185" checksum="D78D25747A2ACE7B" modified="2019-10-16" version="1">MTTLTARTSKIQRSAFTLVELLVVIAIIGILVGLLLPAVQQAREAARRMQCSNNLKQMGVAMHNYHDVHGCFPAGFYRRSYSYSTFSGPGWGWGTMILPQIEENNRYEALQVNNQFASDDPAILEFSQPLVSAFVCPSAPASEDLNPEFKNSSSEPSHGLSTYKGVFGDLNTQYNYSGDDCSYYQGSCIKGGNGIFSANSSTKFRDVTDGTTHTVMIGEVPFGANGTRNSSGDLIQYRGAVWIGVTTGGASSNVATHQTLRGVTASGSQSSLYGINGSSSYAFGSHHPGGAQFVVSDGSTRFFSETMDGVTINRIANKEDGEVTGDDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPV8</accession>
    <name>A0A518IPV8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Xylose operon regulatory protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">xylR_3</name>
        <name evidence="2" type="ORF">Mal33_10690</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="1">
        <location>
            <begin position="290"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="400" mass="45483" checksum="58ACF68F06B19C73" modified="2019-10-16" version="1">MIQRIPAFLDRCRIALLILNESHWSRSVLDGIARYAGEHCGWDFWLQPRGLKEPPKLPEDWCGDGVIARISNEPLRESIARHGLPTVNVSWHGTHCREFPKVISDPQACGRLAAEFFIGRGFEQVGYIGPPDCYNYRDEVWPEVDRVAEEAGCQAYKFEPDPNSPQPDYDFQRLRLVRWIRSLPKPVGIVAWNTTLAREIMLTCGAEGINVPNEVAILAVESDPLVSNLSPMPISQIEQRMEQVGYEAAEELQRLISGGQPRDEPILIAPAGVIEKPSTNTEFATDILVQQAVSFIKRHCDEAITVSDITDHLDISRRSLEERFRKALKRSPAEEIRFARVRVLKDLLRRTTMTHAEISVEASFSCENAMFRFFKRMTGLTPGEFRRNQSIDLPMFPETI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQ01</accession>
    <name>A0A518IQ01_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF1080 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_11460</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010496">
        <property type="entry name" value="3-keto-disaccharide_hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06439">
        <property type="entry name" value="DUF1080"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022132025" description="DUF1080 domain-containing protein" evidence="2">
        <location>
            <begin position="19"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1080" evidence="3">
        <location>
            <begin position="154"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF06439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV55176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="353" mass="38212" checksum="FCACF9FDD7268804" modified="2019-10-16" version="1" precursor="true">MSHSISCLCLIVASTAFAVAQDSPAKTPATNEQPAAETKPADSPAAAAEKPAEPEAEKPKEQPAAEKPKQEAKPNKPAEDKKAAEEKKPAEEKKPEEKAAAKPADASPKSITPIGYTDTQLLPGQPWRIHDLLRPRPRAVTPGADSLAAPPSDAIVLFDGTDLSNWGHQDSKVPGQYTPARWTVKDGYMESKRGTGYLCSLDNVGSCQLHIEWASPKKVVGDGQGRGNSGIKLWGAFEVQVLDSYNNRTYADGQAGAVYGQYPPAVNATLPPGEWQAYDVIYEMPEFDDEGKLTKPAYLTVFHNGVLLHHHRELTGPTGRANSKYSSHPPGGSIMLQDHGNPVRYRNIWVRPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQ91</accession>
    <name>A0A518IQ91_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Small ribosomal subunit biogenesis GTPase RsgA</fullName>
            <ecNumber evidence="3">3.6.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3 7" type="primary">rsgA</name>
        <name evidence="7" type="ORF">Mal33_12350</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="3">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.-" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01854">
        <property type="entry name" value="YjeQ_EngC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01820">
        <property type="entry name" value="GTPase_RsgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030378">
        <property type="entry name" value="G_CP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004881">
        <property type="entry name" value="Ribosome_biogen_GTPase_RsgA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010914">
        <property type="entry name" value="RsgA_GTPase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32120">
        <property type="entry name" value="PTHR32120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03193">
        <property type="entry name" value="RsgA_GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00157">
        <property type="entry name" value="TIGR00157"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50936">
        <property type="entry name" value="ENGC_GTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51721">
        <property type="entry name" value="G_CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CP-type G" evidence="6">
        <location>
            <begin position="155"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="domain" description="ENGC_GTPASE" evidence="5">
        <location>
            <begin position="165"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="205"/>
            <end position="208"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="256"/>
            <end position="264"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="338"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="343"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="345"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="351"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV55265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="383" mass="42082" checksum="76A0268560F2594A" modified="2019-10-16" version="1">MARKKNRSKIRTEFRKKHQGRARDADLTREFKTGDTERLADAHHGERVSGKGALTRHRTVFGDAIDDSNAGLNVQLDSDDALIAGRVLSVHGLQSRVMGDDGVVYSCTVRQLLKSLSTDQRHVIATGDRVAIRTADNQEGMIERVEPRSHVLSRTSRGRQHVIVANVDWLMIVTSAAEPGLKPGLIDRFLLTAEHFGITPIICINKIDLVDAAEYQQLVGTFGQLGYRVLTCSAETGQGIDFLRQVIANRETAVVGQSGVGKSSLLNVIEPGLALRVSSVSSENQKGRHTTTAAKLIPLSSGGFVVDTPGIRQFQLWDITPGEVSALMPDLRPYVSGCRYSDCLHLDEDQCVVKDAVADGRIDARRYDSYCHLLEEDLMNKGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQ92</accession>
    <name>A0A518IQ92_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RNA polymerase sigma factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">fliA</name>
        <name evidence="8" type="ORF">Mal33_12000</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the sigma-70 factor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000943">
        <property type="entry name" value="RNA_pol_sigma70"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007624">
        <property type="entry name" value="RNA_pol_sigma70_r3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007630">
        <property type="entry name" value="RNA_pol_sigma70_r4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012845">
        <property type="entry name" value="RNA_pol_sigma_FliA_WhiG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04539">
        <property type="entry name" value="Sigma70_r3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04545">
        <property type="entry name" value="Sigma70_r4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000770">
        <property type="entry name" value="RNA_pol_sigma-SigE/K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00046">
        <property type="entry name" value="SIGMA70FCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02479">
        <property type="entry name" value="FliA_WhiG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00715">
        <property type="entry name" value="SIGMA70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00716">
        <property type="entry name" value="SIGMA70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="4 5" id="KW-0804">Transcription</keyword>
    <keyword evidence="1 5" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="RNA_pol_sigma70" evidence="6">
        <location>
            <begin position="61"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_sigma70" evidence="7">
        <location>
            <begin position="225"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV55230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="264" mass="30821" checksum="DBC110C45663F53E" modified="2019-10-16" version="1">MATKTAAELEEIQEIWDQYKANPEVRDEYLRNRLVENYMPLVRYNGERIWQRLPEGVELDDLISAGIFGLLDAIDAFDRSRGVKFETYCVPRIRGAMLDELRSMDWVPRLVRSKASKLNEANKKLNEKHGRPPTVQELSEFMQITVPEVEKWQQEANAVGLVSLNKKWYETDSYKDVREIDVLEDKKGEDPTRRVQKNDLMRLVTKGLNRNERLIIILYYYEELTMKEIGATLDLSESRVSQMHSSIVARLQQQLGPRRVEFGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQG0</accession>
    <name>A0A518IQG0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Arylsulfatase</fullName>
            <ecNumber evidence="4">3.1.6.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">atsA_10</name>
        <name evidence="4" type="ORF">Mal33_13070</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="PTM">
        <text evidence="1">The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.</text>
    </comment>
    <dbReference type="EC" id="3.1.6.1" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004065">
        <property type="term" value="F:arylsulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022201812" evidence="2">
        <location>
            <begin position="25"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase" evidence="3">
        <location>
            <begin position="33"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="modified residue" description="3-oxoalanine (Cys)" evidence="1">
        <location>
            <position position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR600917-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV55336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="561" mass="61917" checksum="5264EA8A81BDD75C" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQH3</accession>
    <name>A0A518IQH3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Tryptophan synthase beta chain</fullName>
            <ecNumber evidence="11">4.2.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11 13" type="primary">trpB</name>
        <name evidence="13" type="ORF">Mal33_12840</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + L-serine = D-glyceraldehyde 3-phosphate + H2O + L-tryptophan</text>
            <dbReference type="Rhea" id="RHEA:10532"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
            <dbReference type="ChEBI" id="CHEBI:58866"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="4.2.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 11">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 11">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 5/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 11">Tetramer of two alpha and two beta chains.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 11">Belongs to the TrpB family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.20" evidence="11"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00044"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004834">
        <property type="term" value="F:tryptophan synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06446">
        <property type="entry name" value="Trp-synth_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00133">
        <property type="entry name" value="Trp_synth_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006653">
        <property type="entry name" value="Trp_synth_b_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006654">
        <property type="entry name" value="Trp_synth_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023026">
        <property type="entry name" value="Trp_synth_beta/beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001413">
        <property type="entry name" value="Trp_syn_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00263">
        <property type="entry name" value="trpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00168">
        <property type="entry name" value="TRP_SYNTHASE_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9 11" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="10 11 13" id="KW-0456">Lyase</keyword>
    <keyword evidence="8 11" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="domain" description="PALP" evidence="12">
        <location>
            <begin position="64"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="11">
        <location>
            <position position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="QDV55313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="408" mass="43925" checksum="A601519C1E74B80D" modified="2019-10-16" version="1">MSGTLPKALSPQSVPDSAGRFGSFGGRFVPETLTRALDELVAEYDKAKADPSFQEELDGLWKTFVGRPSPLYFARRLTEACGGAQIWLKREDLNHTGAHKINNTLGQALLTLRMGKTRVIAETGAGQHGVATATACAHFGLPCVVYMGAEDIRRQKPNVFAMKLLGAEIRAVESGSRTLRDAVNEAMRDWMSSVEDTHYIIGSVIGPHPFPMMVRDFQSVIGREARVQSLEAFDGKLPDCVVACVGGGSNAAGIFAPFVADDGVRLVGVEAGGRSSEPGQHASPLTFGRPGVLHGSYSYVMQDDDGQTCDVHSMSAGLDYPGVGPEHSYWKDTGRAEYIQCRDDEAMKAFDMLAKSEGILPALESSHAIAKGMEVAGKMSPDQNLVICLSGRGDKDAMELARLRGEEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQN2</accession>
    <name>A0A518IQN2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Outer membrane efflux protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_13650</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021993202" evidence="4">
        <location>
            <begin position="31"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="90"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="448"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="102"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV55394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="544" mass="59838" checksum="2A626189F66E0CE9" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQU2</accession>
    <name>A0A518IQU2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Prolyl tripeptidyl peptidase</fullName>
            <ecNumber evidence="4">3.4.14.12</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ptpA_1</name>
        <name evidence="4" type="ORF">Mal33_14320</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.4.14.12" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002469">
        <property type="entry name" value="Peptidase_S9B_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00930">
        <property type="entry name" value="DPPIV_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021996709" evidence="1">
        <location>
            <begin position="24"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="domain" description="DPPIV_N" evidence="3">
        <location>
            <begin position="112"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S9" evidence="2">
        <location>
            <begin position="572"/>
            <end position="769"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV55458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="774" mass="87512" checksum="4A690D9281861848" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQV1</accession>
    <name>A0A518IQV1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Leucine Rich repeats (2 copies)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_14420</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="549" mass="60786" checksum="9665372AE9C63CF5" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
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    <name>A0A518IQX1_9BACT</name>
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </comment>
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        <property type="match status" value="1"/>
    </dbReference>
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            <end position="407"/>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="QDV55492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="419" mass="44932" checksum="B1E6E9935DCC331D" modified="2019-10-16" version="1">MTAADSSFQLPDDQRIVITGIGLTAPNGNDWDTFREALLAGRSGVTDYEIRYFGKTLAGVCDFDAKRHQSRKDIRRGTRAGSVGIYAANEAILHSGIDWANTDKSNVGVYIGVTEHGNVETENEIYEIKGFDYDTKYWSHHHNPRTVANSPAGEIALNMGITGPHYTIGAACAAGNAGLIQGAQMLRLNECDLALAGGVSESIHTFGIFAGFNSQGALATHENPELASRPFDVDRNGIVVAEGGCVYVLERLSDARRRGAEIYGELVGYAMNTDATDFVLPNPERQAQCVTKALKRAGMAADQIDIVSTHATGTSSGDAQECLALREAFAGCESVHFNNTKSYIGHAMGAAGALELAGNLSAFKDSVCHPTINVDQLDPACELPGLVINEPKELDDVQYILNNSFGMLGINSVVIIRRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IR76</accession>
    <name>A0A518IR76_9BACT</name>
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        <submittedName>
            <fullName evidence="7">K(+)/H(+) antiporter NhaP2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">nhaP2</name>
        <name evidence="7" type="ORF">Mal33_15300</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
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        <property type="term" value="C:integral component of membrane"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
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        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="TrkA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF51735"/>
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    </dbReference>
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    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
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            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
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        </location>
    </feature>
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        </location>
    </feature>
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        </location>
    </feature>
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        </location>
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    <feature type="transmembrane region" description="Helical" evidence="4">
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        <location>
            <begin position="15"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="domain" description="RCK N-terminal" evidence="6">
        <location>
            <begin position="413"/>
            <end position="515"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
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    </evidence>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
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    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02254"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="QDV55553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="614" mass="66331" checksum="8DE866671776C51D" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRB7</accession>
    <name>A0A518IRB7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="3" type="ORF">Mal33_16180</name>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
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                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021794954" evidence="2">
        <location>
            <begin position="32"/>
            <end position="2161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="993"/>
            <end position="1012"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1018"/>
            <end position="1035"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="2084"/>
            <end position="2105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="2112"/>
            <end position="2130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="2136"/>
            <end position="2153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="2161" mass="239670" checksum="EFF5147DD4A485AC" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IS17</accession>
    <name>A0A518IS17_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Adenylate kinase</fullName>
            <ecNumber evidence="7">2.7.4.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">adk_1</name>
        <name evidence="8" type="ORF">Mal33_18680</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>AMP + ATP = 2 ADP</text>
            <dbReference type="Rhea" id="RHEA:12973"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.3"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="7">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the adenylate kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.3" evidence="7"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004017">
        <property type="term" value="F:adenylate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01428">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000850">
        <property type="entry name" value="Adenylat/UMP-CMP_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033690">
        <property type="entry name" value="Adenylat_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23359">
        <property type="entry name" value="PTHR23359"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00094">
        <property type="entry name" value="ADENYLTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00113">
        <property type="entry name" value="ADENYLATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 6 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6 8" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV55889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="401" mass="45481" checksum="31B2ED3F6035DA2F" modified="2019-10-16" version="1">MQSNNESAHPVNEPIDLEIKDAQVIFKSVWKELEQEVGHENLRFPKELILLGGAPGAGKGTQTQFIMAARGLTCPPIVVSDLLVTPEAQRIKDQGGIVGDGEVIGILLRKLLEPIFRDGAVLDGFPRTRVQVECLKLLVDKITQLHAEFQGTELAVNFRRPTIHAMLLFISEATSISRQLQRGREIEAHNQEVAETGIGRPIELRATDLSPEKAKRRYRVFKEMTWDALQSLKEIYHYHFINAEGPIAEVEANIIGELAYQSSLELDPSTYDRLRGLPLASEITVHARQELVRRLDSYELEHRDLFIRTVDTIDRKFMPIIERHALSGQAIVNSEDELFTDPLALWMLIDIFSERGYHAVVDKHIQATPERIDLETGQIHNRLKTIIRTKISFKGSEIRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IS33</accession>
    <name>A0A518IS33_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">tRNA-specific 2-thiouridylase MnmA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_18710</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016783">
        <property type="term" value="F:sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01990">
        <property type="entry name" value="Alpha_ANH_like_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005232">
        <property type="entry name" value="LarE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022310">
        <property type="entry name" value="NAD/GMP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43169:SF2">
        <property type="entry name" value="PTHR43169:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02540">
        <property type="entry name" value="NAD_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006661">
        <property type="entry name" value="PP-lp_UCP006661"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00268">
        <property type="entry name" value="TIGR00268"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD_synthase" evidence="2">
        <location>
            <begin position="19"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile and sulfur donor" evidence="1">
        <location>
            <position position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR006661-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="273" mass="30096" checksum="DFCF8F5662246A4B" modified="2019-10-16" version="1">MMQTEAIAQRLIDELQRHPRVVVAFSGGVDSAVVAAAAQRALGDKALAVMAISPSVPARQSELAAQVAAEIGIDLQTISTHETERPDYQRNDGQRCFYCKQTLYQTLATIADEHRDSVICSGTNADDLGDHRPGIQAGRDAAVQTPLADLGITKTMVRQLAKHWELSVWDLPAGPCLASRIAYGEPVTVDKLQRIDRAENWLRDEGFAELRVRLHPGQLARIEVPAARIAELVQPEFRQRMSRHFRSLGFQFITVDIEGLRSGNLNQLVSIGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IS40</accession>
    <name>A0A518IS40_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_18950</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="12"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="50" mass="5612" checksum="FC68CE76174838DB" modified="2019-10-16" version="1">MLLNASVAVYRRPYEPVERPSRNTIQGQHGKGSPTPSQSCEFNAQRRLAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISB4</accession>
    <name>A0A518ISB4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Na(+)-translocating NADH-quinone reductase subunit A</fullName>
            <shortName evidence="2">Na(+)-NQR subunit A</shortName>
            <shortName evidence="2">Na(+)-translocating NQR subunit A</shortName>
            <ecNumber evidence="2">7.2.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">NQR complex subunit A</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">NQR-1 subunit A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2 4" type="primary">nqrA</name>
        <name evidence="4" type="ORF">Mal33_19670</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a ubiquinone + H(+) + n Na(+)(in) + NADH = a ubiquinol + n Na(+)(out) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:47748"/>
            <dbReference type="Rhea" id="RHEA-COMP:9565"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="7.2.1.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NqrA family.</text>
    </comment>
    <dbReference type="EC" id="7.2.1.1" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016655">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006814">
        <property type="term" value="P:sodium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00425">
        <property type="entry name" value="NqrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008703">
        <property type="entry name" value="NqrA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022615">
        <property type="entry name" value="NqrA_C_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37839">
        <property type="entry name" value="PTHR37839"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05896">
        <property type="entry name" value="NQRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11973">
        <property type="entry name" value="NQRA_SLBB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01936">
        <property type="entry name" value="nqrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0406">Ion transport</keyword>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0915">Sodium</keyword>
    <keyword evidence="2" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="2" id="KW-1278">Translocase</keyword>
    <keyword evidence="1 2" id="KW-0813">Transport</keyword>
    <keyword evidence="2" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="NQRA_SLBB" evidence="3">
        <location>
            <begin position="260"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF11973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV55988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="445" mass="47831" checksum="E6D08428A86AC20D" modified="2019-10-16" version="1">MTTITKGLNVPISGEPQQLVESSHAITRVALVGDDYIGMKPTMLVNVGDKVKLGQAVFSDKKTAGVTYTAPAAGTVVEINRGAKRRFESLVIEIEGDDSETFETPSDLSSASGEAITEVLTASGLWSAFRTRPFGKVPAPGSQPHSIFVQAMDTHPLAADPSVVMRGKAEQFSIGLNAIKKLTAGKTFVCKNPDADIPGANVDGVTLSDFSGPHPAGLPGTHIHYLDPVGPTKTVWYIGYQDVIAIGQLFATGKLDPTRIISLAGPCVTKPRLIETRLGADLTQLTSGELEGDNLRIVSGSILGGRTATEPCMFLGRYHTQVSVLKEGNEREFLGWQKPGFDKFSITRVFASALTPGKRFAMNTGTHGSERAMVPIGSYERVMPLDILPTQLLRSLIVRDTEEAQQLGALELEEEDLALCTFVCPGKYEFGEILRENLTTIEIEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISF7</accession>
    <name>A0A518ISF7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_20040</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021968927" evidence="2">
        <location>
            <begin position="29"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="177"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="179"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="210" mass="21870" checksum="9E7DD3AFC4335E72" modified="2019-10-16" version="1" precursor="true">MSKQTGLGLTLLALSMVVGCGSSSTPVAENDASKSPATSPAPKPAVDMTPAANVVSQFLDAMRRGGSDTESLSLVTTKAREEFRRTGLVMQPIGSPDAKFEVTRSESVPGQTDAALVHSNWTEPTESGETQSYEVVWAVQQEAGDWKISGLVIGQATGDAPIVVDFENGSDLAAMFQPQRSPAGQQPTLQATAPAADSGVPLDTEAPVIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISG7</accession>
    <name>A0A518ISG7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">RNA polymerase sigma factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_20080</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011517">
        <property type="entry name" value="RNA_pol_sigma70_ECF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07638">
        <property type="entry name" value="Sigma70_ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02999">
        <property type="entry name" value="Sig-70_X6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="188" mass="21499" checksum="E5B23A8CF92B70C2" modified="2019-10-16" version="1">MENATDELLKAQRAKGNPKAEGLFTLVYDDLIRLAGSYLRDEPDRDKLSATSLVHEAYFRMIDQNRVDWAGKTHFFAIGARVMRRILVDHARRVHAQKRGGEWSRIELDDVSTFSMERDADVLALDDLLETLAGLDPTQARIVEMRFFGGMTMKEIAGALQMGLRTVEKEWAMARAWLRNTLDEDARE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISH7</accession>
    <name>A0A518ISH7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">pknB_9</name>
        <name evidence="10" type="ORF">Mal33_20090</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
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        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
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        <property type="project" value="InterPro"/>
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        <property type="entry name" value="Kinase-like_dom_sf"/>
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        <property type="entry name" value="Prot_kinase_dom"/>
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        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
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        <property type="entry name" value="Ser/Thr_kinase_AS"/>
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        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="101"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="420"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="463"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
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            <end position="758"/>
        </location>
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    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="743"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="492"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV56030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="758" mass="84376" checksum="0E5D66917308833A" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISQ4</accession>
    <name>A0A518ISQ4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_20790</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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    </dbReference>
    <dbReference type="Pfam" id="PF07585">
        <property type="entry name" value="BBP7"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="494" mass="52288" checksum="578F83BD2B3238DC" modified="2019-10-16" version="1">MQIRALTTTGLCLGLIWGLLATTTQGQMPSMQGYPPMVSQTSFMVPENMPPGVSQAMYAPTGEMPPGAVAQVGFCSPLGGGSCDSACDGYCGCGNGGGSCGGGGCGCTGCGPGGLLGQICQGGSLNGLQNLCLFCRGSGCSVCQAPSNAANMLGCLGMLAPYTEAGLCAQRWYDFQAEAIFLSMNGSSANQALTSSGVGATNILMSTDDAESDNLGAGFRLTASMMFGAGGNLEATYFGTNHFSHNQEVVDPTNSLYSAFSDFGVAPPGGYNETDQSAVHSLRYSSDIHSGEANYRRRWVGPYCRFQGSWLLGFRYFDLDESLTFATRNELNFSTATSEFLNSTTQTRNALVGAQLGGDLWWNVHPGINFGVGWKGAIFGNRAEQDTHLFYSGETLVGGVPTRTLMNRDEQASDSTTALMSELQVRMAYRLSYSWTFTAAYWFIGIDGVALGAGNVNTSQANRLFNTNTARDVSINIDDSLTMQGFSVGLEYLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISZ9</accession>
    <name>A0A518ISZ9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_22060</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
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            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="104" mass="11646" checksum="F6EF034E60771B6B" modified="2019-10-16" version="1">MSGLDEVIDQLWLHATFEEDPWCVDRAYAAIKDDGVLAVDALIWALGHKDLDLKLLALRLLREFGPVANRAMPAVIDCLFDGDRLVRITAWETARLVEGLETQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IT34</accession>
    <name>A0A518IT34_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_22050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="557" mass="64033" checksum="B4038A8DA950134F" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IT63</accession>
    <name>A0A518IT63_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_22350</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="247" mass="28205" checksum="DD4D6E1B05FCAD0C" modified="2019-10-16" version="1">MSKRHLQFLKNEVIDDVTAQRIREYEGIAKVSVALPVPLEQIVEQVLGLDFDWDIIEEHPGEQILGGLDAVNKKILLNEKHVALFDSKPGLLRSTIGHEAGHYDIDIDRSKLLHPKLPGMDFTPAIAKRHASKADRLIEVLLDRAVSDPRAMALYKKITAGQDTAEQKSAVDRYQSALLMPKWLMHEANEQYDFTQWSDLYRLAEVAQVNISNLTVRLQRLGMIYLRNGDKTIYRSRDEFTGQQTLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITF2</accession>
    <name>A0A518ITF2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_23390</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008930">
        <property type="entry name" value="Terpenoid_cyclase/PrenylTrfase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48239">
        <property type="entry name" value="SSF48239"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="179"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="274"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="183"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="594" mass="63784" checksum="E946047CF385443D" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITX1</accession>
    <name>A0A518ITX1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Arylsulfatase</fullName>
            <ecNumber evidence="8">3.1.6.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">atsA_21</name>
        <name evidence="8" type="ORF">Mal33_25270</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="PTM">
        <text evidence="3">The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the sulfatase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.6.1" evidence="8"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004065">
        <property type="term" value="F:arylsulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032158">
        <property type="entry name" value="DUF4994"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024607">
        <property type="entry name" value="Sulfatase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16385">
        <property type="entry name" value="DUF4994"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00523">
        <property type="entry name" value="SULFATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00149">
        <property type="entry name" value="SULFATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021734980" evidence="5">
        <location>
            <begin position="26"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase" evidence="6">
        <location>
            <begin position="34"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4994" evidence="7">
        <location>
            <begin position="414"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="149"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="462"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="modified residue" description="3-oxoalanine (Cys)" evidence="3">
        <location>
            <position position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR600917-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF16385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV56535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="525" mass="57880" checksum="66B3704C036E699E" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IU04</accession>
    <name>A0A518IU04_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Beta-1,4-mannooligosaccharide phosphorylase</fullName>
            <ecNumber evidence="4">2.4.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_25570</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 130 family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007184">
        <property type="entry name" value="Mannoside_phosphorylase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34106">
        <property type="entry name" value="PTHR34106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04041">
        <property type="entry name" value="Glyco_hydro_130"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016202">
        <property type="entry name" value="PH1107"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="SSF75005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV56565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="358" mass="39923" checksum="CA90279F30961AE0" modified="2019-10-16" version="1">MTQRLRATLLLQPSDITPSQSGWEVVGVLNPAVTVQGDDVVMLARVAETTQEQRCGWTALPRWGCDGTATVDWVCDEDLEKIDARVVMVRKTGNLRLTSVSHLQVWRRSLEPEGRWKAVALVLPLGATEDYGVEDPRITKIDNTYWITYVAVSKLGACTALMSSRDMIAFERHGIIFPSENKDVVLFPEKIDGEFVALHRPNPRSQFSRPQIWIARSSNMIDWGRHEPLFCGSESWEGDRVGSGPPPILIDEGWLLLYHGSESSKVAGKVGRYTAGAILLDRYDPSRVIARSQRPFMVPTADFETCGFVPNVVFPTAMFLQCDVLQVYYGAADRCVGMAEFSKQAVLESMAPRTQSLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IU33</accession>
    <name>A0A518IU33_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Mycocerosic acid synthase</fullName>
            <ecNumber evidence="9">2.3.1.111</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">mas_1</name>
        <name evidence="9" type="ORF">Mal33_25900</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.3.1.111" evidence="9"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050111">
        <property type="term" value="F:mycocerosate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05235">
        <property type="entry name" value="SDR_e1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013120">
        <property type="entry name" value="Far_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041068">
        <property type="entry name" value="HTH_51"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013217">
        <property type="entry name" value="Methyltransf_12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032821">
        <property type="entry name" value="PKS_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020807">
        <property type="entry name" value="PKS_dehydratase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042104">
        <property type="entry name" value="PKS_dehydratase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013968">
        <property type="entry name" value="PKS_KR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010080">
        <property type="entry name" value="Thioester_reductase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18558">
        <property type="entry name" value="HTH_51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16197">
        <property type="entry name" value="KAsynt_C_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08659">
        <property type="entry name" value="KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08242">
        <property type="entry name" value="Methyltransf_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07993">
        <property type="entry name" value="NAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14765">
        <property type="entry name" value="PS-DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00826">
        <property type="entry name" value="PKS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="SSF55048"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01746">
        <property type="entry name" value="Thioester-redct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="B_KETOACYL_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="1 7" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Carrier" evidence="8">
        <location>
            <begin position="2463"/>
            <end position="2540"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="7">
        <location>
            <position position="2500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV56598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="2957" mass="321518" checksum="8684BC1E6AC20A88" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IU39</accession>
    <name>A0A518IU39_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Chemotaxis protein PomA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">pomA</name>
        <name evidence="10" type="ORF">Mal33_25720</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MotA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000540">
        <property type="entry name" value="Flag_MotA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002898">
        <property type="entry name" value="MotA_ExbB_proton_chnl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01618">
        <property type="entry name" value="MotA_ExbB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01307">
        <property type="entry name" value="MOTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="33"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="153"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="178"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="domain" description="MotA_ExbB" evidence="9">
        <location>
            <begin position="102"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV56580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="253" mass="26710" checksum="91F5B0156EE19CFF" modified="2019-10-16" version="1">MDIASLIGVILALGLILGSIALGSAPFSAFIDLPSFLVVIGGAVAAALICFPMKNMVGSPMVAMKVFLNKAPDLQALIKQIVELAETARRDGLLALESKIADVDHPLVKAGLQMAVDGSTPEGVEEVLRTEVSAIAIRHKDGKAVMDQLGRFAPAYGMIGTLMGLIMMLSNMSDPSSIGAGMAVALITTLYGAIVANVFFSPFAEKLGLISRQEMVSMEIAIRGVLAIQSGESPRAIEQKLRTYLPPKQRDSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IU58</accession>
    <name>A0A518IU58_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Leucine--tRNA ligase</fullName>
            <ecNumber evidence="9">6.1.1.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Leucyl-tRNA synthetase</fullName>
            <shortName evidence="9">LeuRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9 14" type="primary">leuS</name>
        <name evidence="14" type="ORF">Mal33_26040</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>ATP + L-leucine + tRNA(Leu) = AMP + diphosphate + L-leucyl-tRNA(Leu)</text>
            <dbReference type="Rhea" id="RHEA:11688"/>
            <dbReference type="Rhea" id="RHEA-COMP:9613"/>
            <dbReference type="Rhea" id="RHEA-COMP:9622"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57427"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78494"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.4"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9 10">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.4" evidence="9"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA editing activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004823">
        <property type="term" value="F:leucine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006429">
        <property type="term" value="P:leucyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.740.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00049_B">
        <property type="entry name" value="Leu_tRNA_synth_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002302">
        <property type="entry name" value="Leu-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025709">
        <property type="entry name" value="Leu_tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43740">
        <property type="entry name" value="PTHR43740"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13603">
        <property type="entry name" value="tRNA-synt_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00985">
        <property type="entry name" value="TRNASYNTHLEU"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="SSF50677"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00396">
        <property type="entry name" value="leuS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 9 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA-synt_1" evidence="11">
        <location>
            <begin position="13"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA-synt_1_2" evidence="13">
        <location>
            <begin position="256"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA-synt_1" evidence="11">
        <location>
            <begin position="712"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="domain" description="Anticodon_1" evidence="12">
        <location>
            <begin position="797"/>
            <end position="906"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="9">
        <location>
            <begin position="713"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="716"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF13603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="QDV56612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="945" mass="106104" checksum="0E17298A1BE6ED6C" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUA9</accession>
    <name>A0A518IUA9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase</fullName>
            <ecNumber evidence="1">1.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">linC</name>
        <name evidence="1" type="ORF">Mal33_26430</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.1.-" evidence="1"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="234" mass="24343" checksum="7F7F9F694FDFF9C5" modified="2019-10-16" version="1">MQDKNFVIVGGSHGIGAGIVRRCVERGAKVTVLSRGIGELADLPGVRHVPLDVTQRGPTADELPDSIDALAYCPGSINLGPLRSVTEQTLRDDFELNVVGAVRCMQACLAGLKSGASASVVLFSTVAGQQGLAMHTSVAAAKGAIEGLTRTWAAELAPKVRVNCIAPALTATQLSERLLATDEKRQAMAAMYPLARHGEVDDIAAAAEFLLSDASSWITGQVLGVDGGLSSLRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUE2</accession>
    <name>A0A518IUE2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_26780</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="295" mass="32075" checksum="385B2668CAC59C03" modified="2019-10-16" version="1">MTDIFTAIGIVLVVSLTLGLLVARSPQPSGVWRTAAMAILLIGAFGNVFYSTGLIVWARYIPHSAVIVWANVVPIAAAISAGLAYRLPNTPHWRQLLASGLLGLLSFGTVFWPLQGFILRPPQPGGNTWSQGVALQTSWSSCSPAAAATLLRANGVDVDESDLMTACLTDNRGTVSLGLYRGVKLFADANDLEVEIVPPSLDQLIIDDQWPVLLMVRLPKTGVEDPRYEHNWGWIPGLGHSVVCFGRLPNGNFIVGDPSIGREQWTMQDMKILWHGDGIRLHKRGEPFDANAPKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUM1</accession>
    <name>A0A518IUM1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 8 10">Thymidine kinase</fullName>
            <ecNumber evidence="2 8 10">2.7.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8 12" type="primary">tdk</name>
        <name evidence="12" type="ORF">Mal33_27770</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8 10">
            <text>ATP + thymidine = ADP + dTMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19129"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17748"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:63528"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.21"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 8 11">Belongs to the thymidine kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.21" evidence="2 8 10"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004797">
        <property type="term" value="F:thymidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071897">
        <property type="term" value="P:DNA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00124">
        <property type="entry name" value="Thymidine_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001267">
        <property type="entry name" value="Thymidine_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020633">
        <property type="entry name" value="Thymidine_kinase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11441">
        <property type="entry name" value="PTHR11441"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00265">
        <property type="entry name" value="TK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF035805">
        <property type="entry name" value="TK_cell"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00603">
        <property type="entry name" value="TK_CELLULAR_TYPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 8 10" id="KW-0237">DNA synthesis</keyword>
    <keyword evidence="6 8 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 8 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="active site" description="Proton acceptor" evidence="8 9">
        <location>
            <position position="78"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="77"/>
            <end position="80"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="137"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR035805-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QDV56778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="193" mass="21620" checksum="8D99D8F3E4F5F36E" modified="2019-10-16" version="1">MNAGKSTILLQSSYNYRERGMNTLILTPELDTRFGTGKVSSRIGLEADAIVFDQVENLRHCVQTQVEAAPLHCVFVDEAQFLTAKQVRQLSDVADHLGVPVMCYGLRTDFQGKLFDGSMQLLAWADVLTEVKTICHCGRKATMVLRIDQHGSPIQQGDQVQIGGNERYLSVCRRHFKQGMASRQTDELPFDET</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUX8</accession>
    <name>A0A518IUX8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative phospholipid ABC transporter permease protein MlaE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">mlaE_1</name>
        <name evidence="2" type="ORF">Mal33_29040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030802">
        <property type="entry name" value="Permease_MalE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30188">
        <property type="entry name" value="PTHR30188"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02405">
        <property type="entry name" value="MlaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="185"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="232"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="273"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="300" mass="32372" checksum="5F1FBDE16466FC73" modified="2019-10-16" version="1">MLAQPDETFRVPSSPNLTHPKPWQLGRRFALTTEMIGKRFIEVLKVVVNLLALVWAVAFIAASPQSWTPLTRMVFARQLLFTAVDGLLVAIRISAAVGVLVIVQSAMWLDAVGATTDGISPVLWKAVIHEIAPLIASLVVVGRSGIAISTELATMLVSGELEVLESQGVDPMTTLIMPRVLSMTLSVFCLAIVVATTMLVMGYMVGWLMGVIHTPWSMFLESLLRESNLLDFAFFVPKTIIAGAFAGAICCADGLTVRGTMSDVSRVASRSGIHAMTAVFGISAILSILIYNRILVFQIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IV38</accession>
    <name>A0A518IV38_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein-glutamate methylesterase/protein-glutamine glutaminase</fullName>
            <ecNumber evidence="3">3.1.1.61</ecNumber>
            <ecNumber evidence="3">3.5.1.44</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">cheB1</name>
        <name evidence="3" type="synonym">cheB</name>
        <name evidence="9" type="ORF">Mal33_29470</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>H2O + L-glutaminyl-[protein] = L-glutamyl-[protein] + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:16441"/>
            <dbReference type="Rhea" id="RHEA-COMP:10207"/>
            <dbReference type="Rhea" id="RHEA-COMP:10208"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29973"/>
            <dbReference type="ChEBI" id="CHEBI:30011"/>
            <dbReference type="EC" id="3.5.1.44"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 3">
            <text>[protein]-L-glutamate 5-O-methyl ester + H2O = H(+) + L-glutamyl-[protein] + methanol</text>
            <dbReference type="Rhea" id="RHEA:23236"/>
            <dbReference type="Rhea" id="RHEA-COMP:10208"/>
            <dbReference type="Rhea" id="RHEA-COMP:10311"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17790"/>
            <dbReference type="ChEBI" id="CHEBI:29973"/>
            <dbReference type="ChEBI" id="CHEBI:82795"/>
            <dbReference type="EC" id="3.1.1.61"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="3">Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.</text>
    </comment>
    <comment type="PTM">
        <text evidence="3">Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CheB family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.61" evidence="3"/>
    <dbReference type="EC" id="3.5.1.44" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000156">
        <property type="term" value="F:phosphorelay response regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008984">
        <property type="term" value="F:protein-glutamate methylesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050568">
        <property type="term" value="F:protein-glutamine glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018277">
        <property type="term" value="P:protein deamination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006482">
        <property type="term" value="P:protein demethylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16432">
        <property type="entry name" value="CheB_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00099">
        <property type="entry name" value="CheB_chemtxs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008248">
        <property type="entry name" value="CheB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035909">
        <property type="entry name" value="CheB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000673">
        <property type="entry name" value="Sig_transdc_resp-reg_Me-estase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01339">
        <property type="entry name" value="CheB_methylest"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000876">
        <property type="entry name" value="RR_chemtxs_CheB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52738">
        <property type="entry name" value="SSF52738"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50122">
        <property type="entry name" value="CHEB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0145">Chemotaxis</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="7">
        <location>
            <begin position="7"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="CheB-type methylesterase" evidence="8">
        <location>
            <begin position="177"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="136"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="136"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="active site" evidence="3 4">
        <location>
            <position position="189"/>
        </location>
    </feature>
    <feature type="active site" evidence="3 4">
        <location>
            <position position="216"/>
        </location>
    </feature>
    <feature type="active site" evidence="3 4">
        <location>
            <position position="312"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="3 5">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV56946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="376" mass="40082" checksum="450B2AEDF3072F6F" modified="2019-10-16" version="1">MFTAPRKILIVDDSPVYRRFVQQTLEGLQGHRIVGQASDGVTALQAIATLRPDVITLDVEMPGMSGLEVLKQIKQISPQTEVIMLSSLTLQSASLTIQAIESGAFDFVLKPQGTDLESNRRKLHKELSERFQVISQNVTRNSGGGQPQPSSSRPAWSPTPTPTRVAASPPGNVPRRAMGSPQIIVIGISTGGPQALRSVVSQLPSDFSVPIAVVQHMPPLFTRSLAEELDRISPLQVFEGTAGDILRAGQIAIAPGGFQMRLQRSANGIVLRVNDDPPERSCRPSVNVLFRSAAEQFGGRAVGVVMTGMGDDGTEGSRAMREQGAHILAQDARSCVVYGMPCAVAEAGLVDEVVGLNDVASKLTALSRRPVLAGRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IV40</accession>
    <name>A0A518IV40_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Gluconolactonase</fullName>
            <ecNumber evidence="3">3.1.1.17</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">gnl_1</name>
        <name evidence="3" type="ORF">Mal33_29640</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.1.17" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004341">
        <property type="term" value="F:gluconolactonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000801">
        <property type="entry name" value="Esterase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013658">
        <property type="entry name" value="SGL"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00756">
        <property type="entry name" value="Esterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08450">
        <property type="entry name" value="SGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022041539" evidence="1">
        <location>
            <begin position="23"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="domain" description="SGL" evidence="2">
        <location>
            <begin position="332"/>
            <end position="563"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="592" mass="65615" checksum="845544449CFDC463" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IV55</accession>
    <name>A0A518IV55_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative oxidoreductase</fullName>
            <ecNumber evidence="2">1.-.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_29720</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EC" id="1.-.-.-" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="249" mass="26456" checksum="07437A7869261F6A" modified="2019-10-16" version="1">MTEKKIAIVTGAGSGIGRHVAIALMENGYHVVLAGRNRETLDETAGLGPEGFASVIPCDVSDADSVGNLFAETVERLGRLDLLFNNAGINAPSVPMDELTIDQWQQVLDVNLTGVFLCTREAFRVMKNQTPQGGRIINNGSISAHVPRPQSIAYTATKHAVAGITKSTALDGRPHNIACGQIDIGNAATEMTRRMEQGVPQADGSLKAEPTMDVREIGRAVLYMASLPLDANVLNMTVMASAMPYVGRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVD7</accession>
    <name>A0A518IVD7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 19">Adenosylcobinamide-GDP ribazoletransferase</fullName>
            <ecNumber evidence="7 19">2.7.8.26</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18 19">Cobalamin synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="17 19">Cobalamin-5'-phosphate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19 20" type="primary">cobS</name>
        <name evidence="20" type="ORF">Mal33_30490</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16 19">Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 19">
            <text>adenosylcob(III)inamide-GDP + alpha-ribazole 5'-phosphate = adenosylcob(III)alamin 5'-phosphate + GMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23560"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57918"/>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
            <dbReference type="ChEBI" id="CHEBI:60487"/>
            <dbReference type="ChEBI" id="CHEBI:60493"/>
            <dbReference type="EC" id="2.7.8.26"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 19">
            <text>adenosylcob(III)inamide-GDP + alpha-ribazole = adenosylcob(III)alamin + GMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16049"/>
            <dbReference type="ChEBI" id="CHEBI:10329"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
            <dbReference type="ChEBI" id="CHEBI:60487"/>
            <dbReference type="EC" id="2.7.8.26"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3 19">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5 19">Cofactor biosynthesis; adenosylcobalamin biosynthesis; adenosylcobalamin from cob(II)yrinate a,c-diamide: step 7/7.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="19">Cell membrane</location>
            <topology evidence="19">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6 19">Belongs to the CobS family.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.26" evidence="7 19"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00148">
        <property type="reaction ID" value="UER00238"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051073">
        <property type="term" value="F:adenosylcobinamide-GDP ribazoletransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008818">
        <property type="term" value="F:cobalamin 5'-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00719">
        <property type="entry name" value="CobS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003805">
        <property type="entry name" value="CobS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34148">
        <property type="entry name" value="PTHR34148"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02654">
        <property type="entry name" value="CobS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 19" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10 19" id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword evidence="13 19" id="KW-0460">Magnesium</keyword>
    <keyword evidence="15 19" id="KW-0472">Membrane</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 19 20" id="KW-0808">Transferase</keyword>
    <keyword evidence="12 19" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="14 19" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="51"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="126"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="155"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="213"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00010561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00015850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00025228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00032605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00032853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="QDV57048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="270" mass="28537" checksum="0BD9EA8908B93C74" modified="2019-10-16" version="1">MSEPTQSSDRQACSLWECFVIAVQFLTRVSIFRQRQLSSDQYRLALRRSVLFFPIVGGFVGLFTAVTFATLLLAGVPALVSALVAVGFEALLTGAFHEDAFADTCDALGGGWTRDQVLEIMKDSRLGTYGTIALVAGVGARAAAIAAMGETDVRWSIIAIVAAAAIGRIAIVVMMATTSPINDRASQARDVAGSQTLKTVIAATLASLPFWSAWLMLAPSCAAASMLVSAITLILFRRKIMRRIGGTTGDLLGASGFLIQLVVTIGSTTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVE1</accession>
    <name>A0A518IVE1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Cobalamin biosynthesis protein CobD</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">cobD</name>
        <name evidence="11" type="ORF">Mal33_30550</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 10">Cofactor biosynthesis; adenosylcobalamin biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Cell membrane</location>
            <topology evidence="2 10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the CobD/CbiB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00148"/>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015420">
        <property type="term" value="F:ABC-type vitamin B12 transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048472">
        <property type="term" value="F:threonine-phosphate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00024">
        <property type="entry name" value="CobD_CbiB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004485">
        <property type="entry name" value="Cobalamin_biosynth_CobD/CbiB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34308">
        <property type="entry name" value="PTHR34308"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03186">
        <property type="entry name" value="CobD_Cbib"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00380">
        <property type="entry name" value="cobD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 10" id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="52"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="89"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="168"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="304"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QDV57054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="328" mass="36099" checksum="02E7D399F6FF2C18" modified="2019-10-16" version="1">MFVILIAVLLDVRWGEPPNRFHPVVWMGSLIAWAKKRCPGDCENRNGNKLRFLWGIAIVVVGSCLVGSIGWIIQVGSSRMISGELVPKPFAWVIVVLVQALVLKSCFGISALYRAGQSVFEALSQEDIPRARTQLAYHLVSRDVEHLSASQISAAAIESVAENTSDSIVAPLFFYVVAGLPGVLIYRFANTCDAMLGYRTPELEWLGKPAARFDDLLNLIPARITAVLMIAANNPFRREASSALKTWLRDARATASPNAGHPMSVAAGLLEVCLEKRNHYRLGWEFPPPTRADISQMLVLFRRTVWLAVILASASCQIAMVFPSRSTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVE7</accession>
    <name>A0A518IVE7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Vitamin B12-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">btuF</name>
        <name evidence="3" type="ORF">Mal33_30580</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002491">
        <property type="entry name" value="ABC_transptr_periplasmic_BD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01497">
        <property type="entry name" value="Peripla_BP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50983">
        <property type="entry name" value="FE_B12_PBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021860869" evidence="1">
        <location>
            <begin position="23"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="domain" description="Fe/B12 periplasmic-binding" evidence="2">
        <location>
            <begin position="60"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="331" mass="36566" checksum="1FD36A91328DB4E1" modified="2019-10-16" version="1" precursor="true">MNHAHLGLRFWLLPLLTLLAFAAGCRQETSNRPETSPSASTQTITDRLDREVPVQQPAQRIISLSPATTELLFALGLGDSVVGATKHCNFPPAALEIPRVGGGTLESISAEVIVAAQPDLVLCKWDYHQPLIESLDRLQVRSMAIGAKNLQELFEEARWIGKLTDRTAEAEALVSRMQNQQQHLLNVVSRVKHDPPIRVFYEVWDDPLMTAGPDSFIDELLTMAGLQNIVSDTAVRYPRISSETVLQGDPQLILAPTTHFEQVDLAEIRSRPGWDLITAVTNQRIYLISGDEISRCGPRVLDALAEIIVAAYPEAREDLQLDATDQTKVAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVH1</accession>
    <name>A0A518IVH1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Arylsulfatase</fullName>
            <ecNumber evidence="7">3.1.6.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">atsA_24</name>
        <name evidence="7" type="ORF">Mal33_30840</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="PTM">
        <text evidence="3">The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the sulfatase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.6.1" evidence="7"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004065">
        <property type="term" value="F:arylsulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032158">
        <property type="entry name" value="DUF4994"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024607">
        <property type="entry name" value="Sulfatase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16385">
        <property type="entry name" value="DUF4994"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00523">
        <property type="entry name" value="SULFATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00149">
        <property type="entry name" value="SULFATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021977645" evidence="4">
        <location>
            <begin position="24"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase" evidence="5">
        <location>
            <begin position="28"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4994" evidence="6">
        <location>
            <begin position="404"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="modified residue" description="3-oxoalanine (Cys)" evidence="3">
        <location>
            <position position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR600917-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF16385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV57083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="507" mass="54928" checksum="77DCC35D5EF67B8E" modified="2019-10-16" version="1" precursor="true">MSKCFIAWLAVGLLAAQTNVALSATSHPNIVVIYADDLGYGDVSCYGATAVATPHIDRIAAEGIRFTDGHAPAATCTPSRYAMLTGQYAWRLKGTGIARGDAPAIIKPGRVTLASMLQDSGYKTGVVGKWHLGLGPDEGADWNGKIAPGPLEIGFDYCFLIPATGDRVPCVYVENHRVVDLDPNDPIQVSFKKKVGDEPTGAENPELLKIHPSHGHDRTIVNGISRIGYMSGGKRARWVDEDMADRITSKAVAYIEENKADPFFLFFSLHDIHVPRVPHPRFVGTTAMGPRGDAIAQTDWCTGEILAALDRLNLTDNTIVLFTSDNGPVVDDGYQDEAVEKLGDHRPAGPFRGGKYSNFEGGTRVPFVLRWPAKVKANQTSDALVCQIDLLHSFAALTGQTLAADAGPDSHNILDALLGEDPKGRDHLVEHARTLALRQGDWKYIEPGKGPAVNKNTNTEVGVAPQGQLYNLRADLREQKNLADQDPQRVVKMKAMLDEIRSDGASR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVN9</accession>
    <name>A0A518IVN9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_31460</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="299" mass="33166" checksum="64F438C2D0881253" modified="2019-10-16" version="1">MNRILHSQSQHNLQSRDGWDCARDHRRRVMAMLLENASPTKRLCVLGAGNCNDIDLPELADAYREVVLVDLDGDAMLRGVEKQFSGASSPQRSAKIKTVVGDLTGISELLSQAVDAPQNIDSIVAAIEARLQQPPDGLRTERFDTVASVCLLSQLVHSVTETIGAHAQLLSIVQAVRRQHLHLLRHLMQPGGRGILITDFVSSLTAPQLPHVPNDQLPQYVRQLLNQQNFFTGLNPAVLAHQMQTDSQFADGLQRLQSTAPWIWDFGPRQYAVCGFQFDTRRDGPPDAIPQPPQRNNDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVU6</accession>
    <name>A0A518IVU6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Lar_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_32010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050043">
        <property type="term" value="F:lactate racemase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018657">
        <property type="entry name" value="LarA-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09861">
        <property type="entry name" value="Lar_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lar_N" evidence="1">
        <location>
            <begin position="19"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="420" mass="45403" checksum="BC515D73FCE39295" modified="2019-10-16" version="1">MSEFPRMFRVRQTFDDTRVASIPDSVAEQLGGSSLASKVSAGQSVAISVGSRGIANIAEIVRAIVDYVKSLGGVPFIVPAMGSHGGGTAEGQAALLGRYGVTDAAMGCEIRSSMETVIVAQAKEGFDVHFDRHASTADHVIVCNRIKPHTRFVGEIESGLMKMLLIGLGKRNGAVVYHQAIQNFSFGQIIRSVAGEVLNRCPIALGVAILENGYDETAAIQAVEPQQLESHERELLLRARAMMPALPFDRADLLIVDKIGKDISGAGMDTNIVGRKYNDHVAREDEFPKIHQIYARGLTAATAGNATGVGLAEYCHQRLVDQMDPVATRINCLTGGHVTAAMVPIHFPTDREVLAAAITQAGLVAPADVRWMWAPNTLEISEVMCSEAYWNQVAERPNLQIVHPPEPIRFDADDQLLEIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVW4</accession>
    <name>A0A518IVW4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_32320</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011453">
        <property type="entry name" value="DUF1559"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07596">
        <property type="entry name" value="SBP_bac_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="311" mass="33941" checksum="3498A01B8E323899" modified="2019-10-16" version="1">MRPLRKQRAFTLVELLVVIAIIGILVGLLLPAVQAAREAARRMQCSNNMKQLGLAMHNYHDVHLKFPPGGLDVGGYRIGWPARIFDFIEEGNRIDAMDGLSPNALVTMQPYRFTTAPHYGDNQIFTDPMPSFACPSSPLGGTAKAAGQIGSIDQGTLHYNANAGSVNYDMVNTSSSSQDYSTSGVIYPKSKVKFAHITDGTSSTILVGECSDRQGWTDSMLNSWGGILPWTWGYYSYSSGGFLQMDNKNLQYPINFEGTTSTNVTAYRSAHPGGAQFSLCDGSVRFLTETMDYVVLDAMATRARGEVVSFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IW08</accession>
    <name>A0A518IW08_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative periplasmic serine endoprotease DegP-like</fullName>
            <ecNumber evidence="3">3.4.21.107</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">mucD_6</name>
        <name evidence="3" type="ORF">Mal33_32690</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.4.21.107" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001940">
        <property type="entry name" value="Peptidase_S1C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13180">
        <property type="entry name" value="PDZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00834">
        <property type="entry name" value="PROTEASES2C"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021893820" evidence="1">
        <location>
            <begin position="28"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="2">
        <location>
            <begin position="260"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="345" mass="36464" checksum="3D58049AAC6EEBE4" modified="2019-10-16" version="1" precursor="true">MISRSLVRIQCGLLAFAVGLSALQADAQQKPSGLTFVSAPSALTGVLQGEAPNSLAELRALEHQQQIVSQRVAKCTVSVQIGFAQGSGVVITADGYVLTAAHVAMRPGQQALMTLSDGRQVHGTTLGMNRHVDAGLIKIDDPAPAEGWPFATLGSSSGVAPGTWCVAVGHPGGYEPDRGAVIRIGRVLIKRETSLVTDCALIGGDSGGPLFDLTGKLIGVHSRIGNDVTDNLHVPIDHYDEHWTRLARGELWGHLPGFRPRIGVQGRKIDERAVIEVVGQNSPAAEAGIRPGDVIMNFGDVTIADFESLKAAVADTMPGEHVQIVLERDGVRKRMILVVGRDPNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IW87</accession>
    <name>A0A518IW87_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alpha/beta hydrolase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_33090</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022220619" evidence="2">
        <location>
            <begin position="24"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S9" evidence="3">
        <location>
            <begin position="181"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV57305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="386" mass="42560" checksum="C34DDD98BF00FF18" modified="2019-10-16" version="1" precursor="true">MTFASFWNRIAFCTLLSLPCHWAASQQSNTDTPKSESPVAKEATETSPTRLPQTEILAYRAADGAIQTAQSPAEWEARRREVLAGMEAIMGAMPGEEKRVPLDVRIDSEEDCGSYVRRLITYQSEPGSRVPAYLSIPKALLADDAKPAAAVLCLHPTDNSVGHKVVVGLGGKANRQYAAELAERGFVTLAPSYPLLANYQPDLEALGWTSGTLKAVWDNMRGIDLLQSLPYVRKESIGAIGHSLGGHNAVYTAVFDPRIQAIVSSCGLDSFLDYYGSVPSVWQLGSGWTSTRYMPRLAEYRGRLEEIPFDFHELIAALAPRPMLIVAPLHDSNFQHDSVDRVAATAKKVYQLHDAADRLQVEHPDCDHDFPEAMRLKAYKLFTETL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWS0</accession>
    <name>A0A518IWS0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PQQ_3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_35510</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025666">
        <property type="entry name" value="PQQ-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13570">
        <property type="entry name" value="PQQ_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PQQ_3" evidence="1">
        <location>
            <begin position="58"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13570"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="86" mass="9465" checksum="B4AA999FFFEB4C64" modified="2019-10-16" version="1">MIYRKRVGNLQSGRPVYASPVLIGDHIYVVTRRSGTLVFDPGDEFEPIAQNKIADDESDFNASPAVSDGKLYLRSDQALYCIGAKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWY3</accession>
    <name>A0A518IWY3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphatidate cytidylyltransferase</fullName>
            <ecNumber evidence="2">2.7.7.41</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">cdsA_1</name>
        <name evidence="2" type="ORF">Mal33_36120</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.7.41" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004605">
        <property type="term" value="F:phosphatidate cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="125"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="158"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="201"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="233"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="303" mass="31681" checksum="FEC43587D4C39B0B" modified="2019-10-16" version="1">MLYQRLATSAVLISIVVALIYLDHRFPTGGLWLLPLLLFFSVGTAIDVTRLWRSANYPVRPLPTKIGVAIVVLIASVPMLWPLSGELYPADCPVGRLGWISVGAIVALGLAIGNEMFRYRPGETGAAGCVMTASFTILYIGVPMAFLVAIRCLGSPHWGLAALISLVAATKAADAGAYFTGRAIGRHKLIPRLSPGKTIEGALGGVAASIGVSFAMFHWLIPALTGTPIDYPIWGPIAFGLVCSNCGMFGDLAESLMKRDSGAKDSGNLLPGLGGVWDVTDSLIATALPGFLCFAIGVAGAPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IX17</accession>
    <name>A0A518IX17_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_36440</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022222826" evidence="2">
        <location>
            <begin position="21"/>
            <end position="938"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="355"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="355"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="938" mass="101887" checksum="C00858B3512ED0F3" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IX76</accession>
    <name>A0A518IX76_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sodium/glucose cotransporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">sglT_4</name>
        <name evidence="8" type="ORF">Mal33_37000</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1730.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038377">
        <property type="entry name" value="Na/Glc_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001734">
        <property type="entry name" value="Na/solute_symporter"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00474">
        <property type="entry name" value="SSF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50283">
        <property type="entry name" value="NA_SOLUT_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="78"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="117"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="154"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="185"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="273"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="376"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="421"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="450"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="479"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="516"/>
            <end position="536"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV57687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="547" mass="59481" checksum="CEFF9A93A56441A9" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IX95</accession>
    <name>A0A518IX95_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_37190</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="499" mass="56373" checksum="0047B8E94A5257A7" modified="2019-10-16" version="1">MGLERPNTERKALDVNLDARRYGSFAEIGAGQEVVRWFFRVGAAAGTIAKSMSAYDMSVSDAIYGQCERYVCRKRLEDMLDHEHSLNLERLRESRGDTTAFFAFADTVSARNFHGTNDCHGWMGIRFQAHPRDQDSQIIIHVRMLDTENALQQEALGIVGVNLLYGAFFLNHEPDQLIESLLDNLSTRRIEIDMIEFSGIAFRHVDNRVMSLRLVQLGLSSAAMFSADGEVLQPSEVLYKKPILVERGSFRPLTNVNVDMLQAAQQKFHLQEDIDPDEVVTLAEITMRNLQANGNIDLRDFLARVDVLAACGMTVLISDYFEYYRLAAYLARYTKKKIGITMGAASLIELFDDKYYTKLDGGILESFGRLFKNDLKLYIYPLLDRTSGELTTIDNLKVASELRTLYRYLVDKGCIEQLDTFDPAHLSTFSREVLQQIQDNNPEWVQHVPPAVAELIQQRGFFGCRRTPKANLPKRAAINSAPLPIDQGMLVPSHAGSIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IX96</accession>
    <name>A0A518IX96_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Nitrogen assimilation regulatory protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ntrC_2</name>
        <name evidence="8" type="ORF">Mal33_37220</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002197">
        <property type="entry name" value="HTH_Fis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002078">
        <property type="entry name" value="Sigma_54_int"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025662">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025943">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02954">
        <property type="entry name" value="HTH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00158">
        <property type="entry name" value="Sigma54_activat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01590">
        <property type="entry name" value="HTHFIS"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00675">
        <property type="entry name" value="SIGMA54_INTERACT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00676">
        <property type="entry name" value="SIGMA54_INTERACT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50045">
        <property type="entry name" value="SIGMA54_INTERACT_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Response regulatory" evidence="7">
        <location>
            <begin position="21"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma-54 factor interaction" evidence="6">
        <location>
            <begin position="158"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="5">
        <location>
            <position position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV57709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="490" mass="52915" checksum="C0D69023A95AECD1" modified="2019-10-16" version="1">MQKETETDAATKRQPDANSAVVLVVDDEPSICWAFEKMLTQQGHRVVTASSAEEGLRLAEEHSPAMVLLDVRLPNEDGISALPKFLAATDNAPVIVMTAFGDLDTAVSAIRRGASDYLIKPFRLADAQRTCRQALRAAADRRNQPATPQPMPSGQQVLVGQSPAMQQAFRQIALVAASDLSVLITGETGTGKELVAAAIHRNSQRADQPYIPIAPVALNPDLIESELFGHAKGAFTGATEDRAGLFEQAQGGTILLDEIGDLPLAAQVKLLRVLEQGEYSRVGDLRVRHANVRIIAATNCDLHQGVRQGTFREDLYYRLTGVQIHLPPLRQRPEDILLLCQHFLKAMDYPAIDAAIDAELLAELQSRPWAGNVRELKNAVQHAAVIARGRSLEATDFPPAKPASGEPPQSLAGSMGESVAAWATDAIADASEPLHDLHARFLAASEPALLRIAIEHTGGNRAKAAEMLGIHRGTLRDRLRAYNMDTSNGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXF7</accession>
    <name>A0A518IXF7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_37720</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="63" mass="6594" checksum="601E196D14D6FBB8" modified="2019-10-16" version="1">MPPETITQSIAAPDGGAEPSAIPLGLCGAIGAREPEVRRFATTSGYRLVSLRDLSNSLQLQIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXJ3</accession>
    <name>A0A518IXJ3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Imidazole glycerol phosphate synthase subunit HisH</fullName>
            <ecNumber evidence="8">4.3.2.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">IGP synthase glutaminase subunit</fullName>
            <ecNumber evidence="8">3.5.1.2</ecNumber>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">IGP synthase subunit HisH</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">ImGP synthase subunit HisH</fullName>
            <shortName evidence="8">IGPS subunit HisH</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">hisH1_2</name>
        <name evidence="8" type="synonym">hisH</name>
        <name evidence="11" type="ORF">Mal33_38270</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + L-glutamine = 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate + H(+) + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24793"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58278"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58475"/>
            <dbReference type="ChEBI" id="CHEBI:58525"/>
            <dbReference type="EC" id="4.3.2.10"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 8">
            <text>H2O + L-glutamine = L-glutamate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:15889"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="EC" id="3.5.1.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 8">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 5/9.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Heterodimer of HisH and HisF.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="4.3.2.10" evidence="8"/>
    <dbReference type="EC" id="3.5.1.2" evidence="8"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004359">
        <property type="term" value="F:glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000107">
        <property type="term" value="F:imidazoleglycerol-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01748">
        <property type="entry name" value="GATase1_IGP_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00278">
        <property type="entry name" value="HisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010139">
        <property type="entry name" value="Imidazole-glycPsynth_HisH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42701">
        <property type="entry name" value="PTHR42701"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000495">
        <property type="entry name" value="Amidotransf_hisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01855">
        <property type="entry name" value="IMP_synth_hisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="11" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6 8" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GATase" evidence="10">
        <location>
            <begin position="37"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="8 9">
        <location>
            <position position="79"/>
        </location>
    </feature>
    <feature type="active site" evidence="8 9">
        <location>
            <position position="183"/>
        </location>
    </feature>
    <feature type="active site" evidence="8 9">
        <location>
            <position position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000495-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QDV57812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="206" mass="22575" checksum="27D2D715E3ED28BB" modified="2019-10-16" version="1">MITIVDYQMGNLRSVSKAIQRVGEETLITSDPGEIASAEKLILPGVGGFKDAIAELNRRDLANPIRDFIDSGRPFLGICLGLQMLFDSSEEGGQHEGLGIIPGEVVRFPADPALKVPHMGWNQVQITQPTPLMQGIEPGTHFYFVHSYYVKPTDRSVVAIEADYGAPFCAAIWRNNLHATQFHPEKSQGNGMKLLKNFVSLDAPGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXJ6</accession>
    <name>A0A518IXJ6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Anaphase-promoting complex, cyclosome, subunit 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_38280</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022031674" evidence="2">
        <location>
            <begin position="34"/>
            <end position="922"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="922" mass="104269" checksum="709E81EA3A706355" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXP2</accession>
    <name>A0A518IXP2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Lysine--tRNA ligase</fullName>
            <ecNumber evidence="6">6.1.1.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Lysyl-tRNA synthetase</fullName>
            <shortName evidence="6">LysRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 9" type="primary">lysS</name>
        <name evidence="9" type="ORF">Mal33_38620</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6 7">
            <text>ATP + L-lysine + tRNA(Lys) = AMP + diphosphate + L-lysyl-tRNA(Lys)</text>
            <dbReference type="Rhea" id="RHEA:20792"/>
            <dbReference type="Rhea" id="RHEA-COMP:9696"/>
            <dbReference type="Rhea" id="RHEA-COMP:9697"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32551"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78529"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6 7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="6 7">Binds 3 Mg(2+) ions per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.6" evidence="6"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004824">
        <property type="term" value="F:lysine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006430">
        <property type="term" value="P:lysyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00775">
        <property type="entry name" value="LysRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04322">
        <property type="entry name" value="LysRS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00252">
        <property type="entry name" value="Lys_tRNA_synth_class2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002313">
        <property type="entry name" value="Lys-tRNA-ligase_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044136">
        <property type="entry name" value="Lys-tRNA-ligase_II_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018149">
        <property type="entry name" value="Lys-tRNA-synth_II_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00982">
        <property type="entry name" value="TRNASYNTHLYS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00499">
        <property type="entry name" value="lysS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 6 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="8">
        <location>
            <begin position="211"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="434"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV57847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="523" mass="59163" checksum="6BBFF0C01C9C22AA" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXT6</accession>
    <name>A0A518IXT6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Chromosome partition protein Smc</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">smc_4</name>
        <name evidence="7" type="ORF">Mal33_39260</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025567">
        <property type="entry name" value="DUF4332"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038729">
        <property type="entry name" value="Rad50/SbcC_AAA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13476">
        <property type="entry name" value="AAA_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14229">
        <property type="entry name" value="DUF4332"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_23" evidence="5">
        <location>
            <begin position="5"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4332" evidence="6">
        <location>
            <begin position="793"/>
            <end position="911"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4332" evidence="6">
        <location>
            <begin position="1118"/>
            <end position="1241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="293"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="914"/>
            <end position="1005"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1022"/>
            <end position="1098"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="470"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="915"/>
            <end position="949"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="963"/>
            <end position="1000"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1030"/>
            <end position="1078"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1079"/>
            <end position="1096"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF14229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV57910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1248" mass="140568" checksum="B96C03889631034C" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXU1</accession>
    <name>A0A518IXU1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="12">General secretion pathway protein K</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Mal33_39190</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the GSP K family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.40.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005628">
        <property type="entry name" value="GspK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038072">
        <property type="entry name" value="GspK_central_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38831">
        <property type="entry name" value="PTHR38831"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03934">
        <property type="entry name" value="T2SSK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158544">
        <property type="entry name" value="SSF158544"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007246"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QDV57903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="583" mass="63042" checksum="6C276CAB4FBCB10C" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IY81</accession>
    <name>A0A518IY81_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_40540</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011204">
        <property type="entry name" value="Virulence_RhuM-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13310">
        <property type="entry name" value="Virulence_RhuM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="122" mass="14043" checksum="F8EFBB573DE7FFA8" modified="2019-10-16" version="1">MTNNLPAPAADDGGEFLLYQTDDGSPRIEVRMADENVWLSQKDMADLFQTTKQNISAHLQNVYEEGELHPQATVKKYLTVRTEGKRQVSRQVEHYNLDAIISVGYRARSHRGTQFRIWQPRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYB6</accession>
    <name>A0A518IYB6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">DNA integrity scanning protein DisA</fullName>
            <ecNumber evidence="7">2.7.7.85</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">disA</name>
        <name evidence="7" type="ORF">Mal33_40960</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2 ATP = 3',3'-c-di-AMP + 2 diphosphate</text>
            <dbReference type="Rhea" id="RHEA:35655"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:71500"/>
            <dbReference type="EC" id="2.7.7.85"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.7.85" evidence="7"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106408">
        <property type="term" value="F:diadenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1700.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00840">
        <property type="entry name" value="DacZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014499">
        <property type="entry name" value="DAC_DacZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036888">
        <property type="entry name" value="DNA_integrity_DisA_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003390">
        <property type="entry name" value="DNA_integrity_scan_DisA_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02457">
        <property type="entry name" value="DAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF019073">
        <property type="entry name" value="UCP019073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143597">
        <property type="entry name" value="SSF143597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51794">
        <property type="entry name" value="DAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 7" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DAC" evidence="6">
        <location>
            <begin position="127"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV58079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="314" mass="34620" checksum="9E85DC25303A5655" modified="2019-10-16" version="1">MASQRFTKHSGAVLGVAVNMAEVLSADAILILLDGSTDWKRLRSETKETKTPILVAADTAEDLEGASEFGLIPLVLNKEKAPLLERLQHALLEAATDELIRTNGDVIAIYSGFQQGRMDSISHLQLDERMRRLTVRDLQRLESSVPLKTIKAVVDLAVQIGREGREGKAVGTLFVVGHSRRVMEHCNDGGLDPFRGANRKARNLYDRRVQEDVKEIAQMDGAFVVNSDGNIERSRQMLEVAHQDLTMSKGLGARHWAAAAISAKTKAVAVVVSQSTGTVRLYQNGELVMRIEPMDKAVKWQEFNYEPPAPTPEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYN6</accession>
    <name>A0A518IYN6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_42170</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022022874" evidence="2">
        <location>
            <begin position="21"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="169" mass="18118" checksum="2930921C7710F22A" modified="2019-10-16" version="1" precursor="true">MRTLSAVAIVCLMLSSLSTAEEVSQRDQKLAAYLSGSKFVGQFTVLGKSEEKLPTEEYTLKKVEKIPGGDLFLITARIKYGDKDVEVPLPIPIVWAGDTPMISLDDFTIPGMGTFSAKIVISKGRYAGTWSHDEHGGHMFGVIEKPEVAGAEASEKPGSDAKPEAKSGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYP6</accession>
    <name>A0A518IYP6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Lipoprotein-releasing system transmembrane protein LolE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">lolE</name>
        <name evidence="9" type="ORF">Mal33_42210</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="15"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="375"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="418"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="475"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="8">
        <location>
            <begin position="19"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="7">
        <location>
            <begin position="401"/>
            <end position="508"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV58204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="515" mass="56712" checksum="877C447816284655" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ81</accession>
    <name>A0A518IZ81_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">N, N'-diacetylbacillosaminyl-diphospho-undecaprenol alpha-1,3-N-acetylgalactosaminyltransferase</fullName>
            <ecNumber evidence="3">2.4.1.290</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">pglA_2</name>
        <name evidence="3" type="ORF">Mal33_44100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.4.1.290" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102335">
        <property type="term" value="F:N,N'-diacetylbacillosaminyl-diphospho-undecaprenol alpha-1,3-N-acetylgalactosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="52"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="405" mass="44168" checksum="132ACC8CDB2A7A44" modified="2019-10-16" version="1">MANDVLIDEHTHQATIATPHTDPASGSQTKAGSRRSSRVLRVLHVVNGQHFSGAERVQTHLARCLPENGVTADFALLTPDRFPKHFDVESSQLFDMKMRNRWDIGAARRVAKLARDGNYQLLHAHTPRSAMIAAYASRQARRPWVYHVHSPAAADSTRPIQNRINAMTERFCLLSTSHQIAVSNSLRDHTIASGFDPETVTTVHNGVPMIRPPRTEFPQVGGVWTLGIVALHRPRKGLETLLDAQRIVRDAGFDVRLRCVGPFETPAYEASIRSRIDQLQLGPDVEFTGFVDDIPAALAKLDAMVLPSLFGEGLPMVVLEAMAAAVPVIATRVEGTPEAISHDSEGLLAEAGNPVDLAAQIQRLVSGEVSWHDLAEAAAARHAAEFSDVAMARGVADVYRKVIDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZD1</accession>
    <name>A0A518IZD1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cytochrome-c oxidase</fullName>
            <ecNumber evidence="3">7.1.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">ctaD_2</name>
        <name evidence="12" type="ORF">Mal33_44730</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>4 Fe(II)-[cytochrome c] + 8 H(+)(in) + O2 = 4 Fe(III)-[cytochrome c] + 4 H(+)(out) + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:11436"/>
            <dbReference type="Rhea" id="RHEA-COMP:10350"/>
            <dbReference type="Rhea" id="RHEA-COMP:14399"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="EC" id="7.1.1.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Energy metabolism; oxidative phosphorylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the heme-copper respiratory oxidase family.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.9" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00705"/>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070469">
        <property type="term" value="C:respirasome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004129">
        <property type="term" value="F:cytochrome-c oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015990">
        <property type="term" value="P:electron transport coupled proton transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006119">
        <property type="term" value="P:oxidative phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022904">
        <property type="term" value="P:respiratory electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.210.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023616">
        <property type="entry name" value="Cyt_c_oxase-like_su1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036927">
        <property type="entry name" value="Cyt_c_oxase-like_su1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000883">
        <property type="entry name" value="Cyt_C_Oxase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023615">
        <property type="entry name" value="Cyt_c_Oxase_su1_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014241">
        <property type="entry name" value="Cyt_c_oxidase_su1_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035973">
        <property type="entry name" value="Cyt_c_oxidase_su3-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013833">
        <property type="entry name" value="Cyt_c_oxidase_su3_a-hlx"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10422">
        <property type="entry name" value="PTHR10422"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00115">
        <property type="entry name" value="COX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01165">
        <property type="entry name" value="CYCOXIDASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81442">
        <property type="entry name" value="SSF81442"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81452">
        <property type="entry name" value="SSF81452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02891">
        <property type="entry name" value="CtaD_CoxA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50855">
        <property type="entry name" value="COX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00077">
        <property type="entry name" value="COX1_CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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        <source>
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        </source>
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    <sequence length="852" mass="94177" checksum="12E1227CB43E359A" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZH7</accession>
    <name>A0A518IZH7_9BACT</name>
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    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
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                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
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                <person name="Lage O.M."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
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    </feature>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="76" mass="8435" checksum="73694C85934C85B7" modified="2019-10-16" version="1">MNQDVSNEPSTDDEDSIRLDNFIKLTGVVGTGGQAKMLIQNGEVTVNGEVETRRRKKLTIGDEIEVLGEVFRVEQD</sequence>
</entry>
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    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
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                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
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                <person name="Spormann A.M."/>
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                <person name="Ovreas L."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZJ8</accession>
    <name>A0A518IZJ8_9BACT</name>
    <protein>
        <recommendedName>
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            <shortName evidence="3">RRF</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Ribosome-releasing factor</fullName>
        </alternativeName>
    </protein>
    <gene>
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        <name evidence="6" type="ORF">Mal33_45360</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the RRF family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006415">
        <property type="term" value="P:translational termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00040">
        <property type="entry name" value="RRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002661">
        <property type="entry name" value="Ribosome_recyc_fac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023584">
        <property type="entry name" value="Ribosome_recyc_fac_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036191">
        <property type="entry name" value="RRF_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20982">
        <property type="entry name" value="PTHR20982"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01765">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55194">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00496">
        <property type="entry name" value="frr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="21"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV58513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="186" mass="20773" checksum="FADF520179FDF61C" modified="2019-10-16" version="1">MSAEEIQLDAEERMEKAVAHLKHSLTGIRTGRATPGLVDSIRVEVYGSQTPLKQLASIGTPEPQQIVIRPYDQSTIKEIEKAIVAGDLGLNPQNDGHMIRLNVPPLSTEVRKKMVARIKELSEEAKVSIRNIRRDANKAADGEEKDKTMSEDDRDRVKNEIQDLTKKYESQIGEVAKARESEVMEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZM9</accession>
    <name>A0A518IZM9_9BACT</name>
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        <submittedName>
            <fullName evidence="6">Planctomycete cytochrome C</fullName>
        </submittedName>
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        <name evidence="6" type="ORF">Mal33_45700</name>
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        <name type="scientific">Rosistilla oblonga</name>
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            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="term" value="F:heme binding"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
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            <end position="20"/>
        </location>
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            <begin position="21"/>
            <end position="1101"/>
        </location>
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        <location>
            <begin position="43"/>
            <end position="101"/>
        </location>
    </feature>
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            <begin position="161"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="domain" description="PSD1" evidence="4">
        <location>
            <begin position="830"/>
            <end position="1068"/>
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    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="760"/>
            <end position="794"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
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    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV58547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1101" mass="122605" checksum="3386FE21349183C1" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
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    <name>A0A518J075_9BACT</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_47690</name>
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    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
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            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
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                <person name="Spormann A.M."/>
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                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
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                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">Mal33</strain>
        </source>
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            <end position="31"/>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="QDV58744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="622" mass="69155" checksum="B5C71C5A577719BA" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0E2</accession>
    <name>A0A518J0E2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Photosystem I assembly protein Ycf3</fullName>
        </submittedName>
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    <gene>
        <name evidence="4" type="ORF">Mal33_48000</name>
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    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
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        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="4"/>
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</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
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        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
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    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
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                <person name="Meyerdierks A."/>
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                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
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                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
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                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="project" value="UniProtKB-KW"/>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="PSCyt2" evidence="2">
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            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="PTM">
        <text evidence="1">The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.</text>
    </comment>
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        <property type="protein sequence ID" value="QDV59095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
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    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022191452" evidence="2">
        <location>
            <begin position="21"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase" evidence="3">
        <location>
            <begin position="24"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="modified residue" description="3-oxoalanine (Cys)" evidence="1">
        <location>
            <position position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR600917-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV59095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="513" mass="57911" checksum="5C5A1732E57E4ED5" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1B4</accession>
    <name>A0A518J1B4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Anaerobic ribonucleotide reductase-activating protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Mal33_51550</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Rosistilla</taxon>
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    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="F:metal ion binding"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
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        <property type="entry name" value="NrdG"/>
    </dbReference>
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        <property type="entry name" value="Organic_radical-activating"/>
    </dbReference>
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        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30352">
        <property type="entry name" value="PTHR30352"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30352:SF2">
        <property type="entry name" value="PTHR30352:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
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    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV59129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="212" mass="23389" checksum="9E9034912DF87F98" modified="2019-10-16" version="1">MTQSISINRIHYPIHSLGFGARVGVWFQGCQIQCPGCVSRDTWELGTNSIQLDDLAQTLLPWTGAADGLTISGGEPFDQLDAVAALVKWWRTKNKGDVLLFSGYSAELLWDRYPEIVAQLDVLISEPYDAKQPQSQPLRGSDNQRMHLLTPIAAQRYANLDEAPTLDLCFDDDTVWIAGIPKPNAMAEIRRRLTAMGFAAGTSDQLLDGVRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1C0</accession>
    <name>A0A518J1C0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_51710</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02436">
        <property type="entry name" value="TIGR02436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="180" mass="20381" checksum="E9124BDDF86A3BC8" modified="2019-10-16" version="1">MSDRIYSHRDLIVYQKSFAAGKRVFELSQTFPREEMYSLTDQVRRSSRSVSANIAEAWRKRRYQKHFCSTLNIAEAEAAETQVWIEYASAHGYIDDETASKASAYYEEILRMIVKMIHGSSNWCDLKSREAGKAGREGVRESESRYGIAHESPVIDQYALLSPSPDLPDSPSSAAESKDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1F3</accession>
    <name>A0A518J1F3_9BACT</name>
    <protein>
        <submittedName>
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        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">btrG</name>
        <name evidence="2" type="ORF">Mal33_51900</name>
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    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="4.3.2.6" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="GGCT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036568">
        <property type="entry name" value="GGCT-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06094">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GGACT" evidence="1">
        <location>
            <begin position="7"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="143" mass="15990" checksum="8AE6BBA8FCFE271D" modified="2019-10-16" version="1">MGAAVNFFVYGTLKRGECRERMWPHAPLQIQAAFVRGCLYDLGPYPAMIAGGDWVAGEVWSIATQHVQQTLAVLDEIEDYDASRANNLYNRLQVPWHLRPDAAAADSKAYTYHYARTEYLMAGQRIKSPADDPVQWPSLGSTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1L6</accession>
    <name>A0A518J1L6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative FAD-binding dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_52500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
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            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039650">
        <property type="entry name" value="HdrA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43498">
        <property type="entry name" value="PTHR43498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021790628" evidence="1">
        <location>
            <begin position="22"/>
            <end position="614"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="614" mass="66585" checksum="1D08E8690CEF2CB2" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1T2</accession>
    <name>A0A518J1T2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidyl-prolyl cis-trans isomerase</fullName>
            <ecNumber evidence="4">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">slyD</name>
        <name evidence="6" type="ORF">Mal33_53230</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 3 4">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the FKBP-type PPIase family.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase FKBP-type" evidence="5">
        <location>
            <begin position="6"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV59295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="161" mass="17639" checksum="C0A4E8B08E1D7B0A" modified="2019-10-16" version="1">MQITADKVVAFDYKLTDDAGELIDSSEGHEPLLYLHGQGGIIEGLERALEGLKVGDTLNITIPPEDGYGLRSDELLQEVPRDEFEEVDEFEVGMQFEADTPDGPMIFSITEVGDELIKVDGNHPLAGETLTFDVTIREVRDATAEELEHGHAHGDGGHDHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1Z0</accession>
    <name>A0A518J1Z0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cyclic di-GMP phosphodiesterase response regulator RpfG</fullName>
            <ecNumber evidence="4">3.1.4.52</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpfG_6</name>
        <name evidence="4" type="ORF">Mal33_53760</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.4.52" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071111">
        <property type="term" value="F:cyclic-guanylate-specific phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037522">
        <property type="entry name" value="HD_GYP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51832">
        <property type="entry name" value="HD_GYP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="1"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="HD-GYP" evidence="3">
        <location>
            <begin position="143"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV59348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="363" mass="40445" checksum="AE0717BAF205F3BB" modified="2019-10-16" version="1">MIVDDVEVNILTVQGYLKKVGYRDFVTTSNPHDALKLIHDANPDVLLLDIQMPEISGLDILRVMGADPVLQHLPVLVLTADQDPVTKQRALDLGANDFLQKPIDPHDLVPRVRNALVLKAHHDQLSRQATWLEQQVKARTAALLASQQQLILSLARAAEHRDNDTANHVIRVGRYAGVIARKLGYLSKRIPMLELAAQLHDVGKIGIPDAILLKPGALEPDEYELMKNHCSFGRKIIAPISGKDLEVLRTHATLGNQILKDPCSPLLKLAAKIAQCHHERWDGKGYPLGLAGNDIPIEARIVSIADVYDALSSKRPYKEPFPRQKCFDIIREGRGTQFDPQLVDAFFSCSEEIIQIQLELMDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J214</accession>
    <name>A0A518J214_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_54050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011453">
        <property type="entry name" value="DUF1559"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07596">
        <property type="entry name" value="SBP_bac_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="313" mass="33718" checksum="0BA7F6715C5AE404" modified="2019-10-16" version="1">MLNRNVSTQKRAAFTLVELLVVIAIIGILVGLLLPAVQSAREAARRMQCGNNLKQLGLAMHNYHDVYNSLPYGANAGWGHDWTAFILPQIEQTPLYDTIPTPFNDSGAWTGTDARSLALIALAQTAVPAFHCPSQIGPANEAKDVNGLANRAINNYLACAGGNAETDNNGAGGMDSSNGMFMASLFTSSNPIPPRKFRDVIDGLSNTVMIGESQYMLDSDKGCNICDRFLFYHMNYDSGSGSDFSESLGSTFYRINSKEVNNTERELSYSSYHPGGAQVALGDGSTRFVSETVDLATWQALGSRDGGETIGDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J2E4</accession>
    <name>A0A518J2E4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator SlyA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_55390</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01047">
        <property type="entry name" value="MarR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="6"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="150" mass="17070" checksum="37C842085C731F1C" modified="2019-10-16" version="1">MHFDSESSPGFAIGRVAYLIRSGMAAELKKAGWPFSPEETQTLITLSDAGEPRSMNELASLMIRDPTTVKRQLDRLVEHQFVERSASSEDARIVMIRLTRRGEQKLQKILPLLDDLRKTALQEIPKSDLETTQNVLRKMQINLRNHVAKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ILY5</accession>
    <name>A0A518ILY5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">D-inositol 3-phosphate glycosyltransferase</fullName>
            <ecNumber evidence="3">2.4.1.250</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">mshA_1</name>
        <name evidence="3" type="ORF">Mal33_00500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.4.1.250" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102710">
        <property type="term" value="F:D-inositol-3-phosphate glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="71"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="162"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="353" mass="37930" checksum="5F7D25283067BB41" modified="2019-10-16" version="1">MNAGRKIIYDSRWISPTGIGRFASELNDRLGCLQHQAIGGSPTSPLDCLRIAWLMWRTDSAFFSPGFNVPLAWPMFAKQPYVFTIHDLIYVNHPAEASLAKRLYCEHVIRPAARRAYKVLTVSEFSKQEIVAWAGIDPSQVEVVYNGVGSAFTVAGPLHQIDHPYVLYVGNQRPHKNVGGLLHAFAKLSDRTEARLAITGTATAETDATIAKLSLGDRVCFLGKLSDDQLAAAYRGAQVTVLASEYEGFGLPVIESMACGTPVVCSNVTSLPEVAGGAAVLVDTDPDSIAEGLLRVLQDESLRDTLAAAGLVRAADFSWEATAAKVQQVLQPLVTAAPVTHSNAVQTLEASAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IM04</accession>
    <name>A0A518IM04_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_00660</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="64" mass="7087" checksum="E23E4D086B2A7EC5" modified="2019-10-16" version="1">MKTNGLSYNSRKALMVNIGDSAGSEIANLIQRMSAQIDELQRNKVSVTRIVPNQEPQMAGEEPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IM41</accession>
    <name>A0A518IM41_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Asparagine synthetase [glutamine-hydrolyzing] 3</fullName>
            <ecNumber evidence="9">6.3.5.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">asnO</name>
        <name evidence="9" type="ORF">Mal33_01060</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the asparagine synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.4" evidence="9"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004066">
        <property type="term" value="F:asparagine synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006529">
        <property type="term" value="P:asparagine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01991">
        <property type="entry name" value="Asn_Synthase_B_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00712">
        <property type="entry name" value="AsnB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006426">
        <property type="entry name" value="Asn_synth_AEB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001962">
        <property type="entry name" value="Asn_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033738">
        <property type="entry name" value="AsnB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00733">
        <property type="entry name" value="Asn_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13537">
        <property type="entry name" value="GATase_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001589">
        <property type="entry name" value="Asn_synthetase_glu-h"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01536">
        <property type="entry name" value="asn_synth_AEB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0061">Asparagine biosynthesis</keyword>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 5" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="9" id="KW-0436">Ligase</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="8">
        <location>
            <begin position="2"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="active site" description="For GATase activity" evidence="5">
        <location>
            <position position="2"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="293"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for beta-aspartyl-AMP intermediate formation" evidence="7">
        <location>
            <position position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001589-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001589-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR001589-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV54160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="635" mass="70568" checksum="D4BF2F4E5D98FD87" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IM50</accession>
    <name>A0A518IM50_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF1080 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_01170</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010496">
        <property type="entry name" value="3-keto-disaccharide_hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06439">
        <property type="entry name" value="DUF1080"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021769344" description="DUF1080 domain-containing protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1080" evidence="2">
        <location>
            <begin position="26"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="213" mass="23763" checksum="2EDA91AD3E8280F0" modified="2019-10-16" version="1" precursor="true">MRRLFACFLLLFPIVAVAQSPAPEAGFTPLFDGKSLQGWEGDANWFRVDDGAIVAGSASETIPNNFFLATTEQYEDFELRLEAKLVGAGQNAGVQFRTQRIPNHHEVSGYQADMGTAGGKPIWGSLYDESRRNKMLAVPDPAAVEEVLESDDWNRIRVRCQGARIQIWLNDLQTVDYTETDPQIERTGIIALQIHGGKPAVASYRNIRIQRLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMG0</accession>
    <name>A0A518IMG0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">LexA repressor</fullName>
            <ecNumber evidence="12">3.4.21.88</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12 16" type="primary">lexA</name>
        <name evidence="16" type="ORF">Mal33_02280</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>Hydrolysis of Ala-|-Gly bond in repressor LexA.</text>
            <dbReference type="EC" id="3.4.21.88"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="12">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 12 13">Belongs to the peptidase S24 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.88" evidence="12"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06529">
        <property type="entry name" value="S24_LexA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00015">
        <property type="entry name" value="LexA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006200">
        <property type="entry name" value="LexA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039418">
        <property type="entry name" value="LexA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036286">
        <property type="entry name" value="LexA/Signal_pep-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006199">
        <property type="entry name" value="LexA_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006197">
        <property type="entry name" value="Peptidase_S24_LexA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015927">
        <property type="entry name" value="Peptidase_S24_S26A/B/C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01726">
        <property type="entry name" value="LexA_DNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00717">
        <property type="entry name" value="Peptidase_S24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00726">
        <property type="entry name" value="LEXASERPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51306">
        <property type="entry name" value="SSF51306"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00498">
        <property type="entry name" value="lexA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12 13" id="KW-0068">Autocatalytic cleavage</keyword>
    <keyword evidence="4 12" id="KW-0227">DNA damage</keyword>
    <keyword evidence="10 12" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3 12" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8 12" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 12 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 12" id="KW-0678">Repressor</keyword>
    <keyword evidence="11 12" id="KW-0742">SOS response</keyword>
    <keyword evidence="9 12" id="KW-0804">Transcription</keyword>
    <keyword evidence="7 12" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="LexA_DNA_bind" evidence="15">
        <location>
            <begin position="5"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S24" evidence="14">
        <location>
            <begin position="84"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="12">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="active site" description="For autocatalytic cleavage activity" evidence="12">
        <location>
            <position position="123"/>
        </location>
    </feature>
    <feature type="active site" description="For autocatalytic cleavage activity" evidence="12">
        <location>
            <position position="161"/>
        </location>
    </feature>
    <feature type="site" description="Cleavage; by autolysis" evidence="12">
        <location>
            <begin position="90"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF01726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="QDV54278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="200" mass="22390" checksum="0F7F2D7011D627C2" modified="2019-10-16" version="1">MAISTRLTTRQQTVYDMIRDKIVLRGYGPTVREIGEHFDIKSPNGVMCHLKALERKGLIRRSPNKSRAIELTNDADRSAKSMPMAGQVMAGSGTLTFEKAERKDLSDMFYGEDRFLLEVSGDSMVDAHITDGDMVVVQKQDHAQAGQMVVAQTTQGDVTLKYWYPEEGRIRLQPANREMEPIYVREATVIGIVVGVVRSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INY9</accession>
    <name>A0A518INY9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">S-adenosylmethionine:tRNA ribosyltransferase-isomerase</fullName>
            <ecNumber evidence="5">2.4.99.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Queuosine biosynthesis protein QueA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 6" type="primary">queA</name>
        <name evidence="6" type="ORF">Mal33_07660</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>7-aminomethyl-7-carbaguanosine(34) in tRNA + S-adenosyl-L-methionine = adenine + epoxyqueuosine(34) in tRNA + H(+) + L-methionine</text>
            <dbReference type="Rhea" id="RHEA:32155"/>
            <dbReference type="Rhea" id="RHEA-COMP:10342"/>
            <dbReference type="Rhea" id="RHEA-COMP:10346"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:82833"/>
            <dbReference type="ChEBI" id="CHEBI:82834"/>
            <dbReference type="EC" id="2.4.99.17"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">tRNA modification; tRNA-queuosine biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the QueA family.</text>
    </comment>
    <dbReference type="EC" id="2.4.99.17" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00392"/>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051075">
        <property type="term" value="F:S-adenosylmethionine:tRNA ribosyltransferase-isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008616">
        <property type="term" value="P:queuosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1780.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00113">
        <property type="entry name" value="QueA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003699">
        <property type="entry name" value="QueA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042118">
        <property type="entry name" value="QueA_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042119">
        <property type="entry name" value="QueA_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036100">
        <property type="entry name" value="QueA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30307">
        <property type="entry name" value="PTHR30307"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02547">
        <property type="entry name" value="Queuosine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111337">
        <property type="entry name" value="SSF111337"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00113">
        <property type="entry name" value="queA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4 5" id="KW-0671">Queuosine biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 5 6" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV54801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="402" mass="44538" checksum="65B4749426AE91D9" modified="2019-10-16" version="1">MGLCATASSPDDDSSVLFFLKTKQSRRAGLRQNLARAAHQCSQRKPPAKPSPVSELDLYDYQLPRELIAQHPLSQRADARLMVVDRRSGSIEHHYVRDLPSLVEPNDAMVFNDSRVIPARLVGLRSQTGGRWQGLFVRKDNETGLWEILSRTRGKLKVGESITLEDRDARPVETLEVIARLPDGHLAVRPGSDGEPAELLERFGRVPLPPYIREGQMVDDDVKTYQTVFARDPGSIAAPTAGLHFTPELLKQLQAKGVQSHAVTLHVGIGTFRPVQTETLDEHEMHYEWASISAETAEKLNAARAAGGRVLAVGTTSVRTLETVAAENDQLVGWTGMTNLFVRPPYKFGAVDRMLTNFHLPKSTLLMLVSAFAGRELIMEAYAAAIAEEYRFFSYGDAMLII</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP41</accession>
    <name>A0A518IP41_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 14">Crossover junction endodeoxyribonuclease RuvC</fullName>
            <ecNumber evidence="11 14">3.1.21.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13 14">Holliday junction nuclease RuvC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12 14">Holliday junction resolvase RuvC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14 15" type="primary">ruvC</name>
        <name evidence="15" type="ORF">Mal33_08260</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 14">Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 14">
            <text>Endonucleolytic cleavage at a junction such as a reciprocal single-stranded crossover between two homologous DNA duplexes (Holliday junction).</text>
            <dbReference type="EC" id="3.1.21.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="14">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 14">Belongs to the RuvC family.</text>
    </comment>
    <dbReference type="EC" id="3.1.21.10" evidence="11 14"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008821">
        <property type="term" value="F:crossover junction endodeoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16962">
        <property type="entry name" value="RuvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00034">
        <property type="entry name" value="RuvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020563">
        <property type="entry name" value="X-over_junc_endoDNase_Mg_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002176">
        <property type="entry name" value="X-over_junc_endoDNase_RuvC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30194">
        <property type="entry name" value="PTHR30194"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02075">
        <property type="entry name" value="RuvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00696">
        <property type="entry name" value="RSOLVASERUVC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00228">
        <property type="entry name" value="ruvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01321">
        <property type="entry name" value="RUVC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 14" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7 14" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="8 14" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5 14 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 14" id="KW-0540">Nuclease</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="14">
        <location>
            <position position="24"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00014685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00029488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00030265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00030973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="QDV54861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="179" mass="18786" checksum="992B47C7BB08EB17" modified="2019-10-16" version="1">MGNAKVKGKVAAGGSTGGTILGVDPGLNITGYGVIRSVAGGIELLEAGIIRTKAKASLERRLLDLHEGLGEVIAAHKPSVLALEQLYSHYKRPQTAILMGHARGVICLLAAQAGIAIESFEATRVKRMMTGNGHAPKDQMQMAVKLQLNLATVPEPPDVADALAIALCQQQMSSMQVQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPD9</accession>
    <name>A0A518IPD9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_09030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="154" mass="16087" checksum="67A6BACA81942CD0" modified="2019-10-16" version="1">MMDLQFQNPKARPACGASSRLLRLASAIPLIVLMTGCGPTGIERYPISGTVTYRGQPVKHGTIMFEPDASKGNSGAAGSATIVDGKFDSSADGTGFTGGPQIVSIQGFSGVDANPEYAPYGTPIGEGKSYIKSFDFPENEAVEQDFEMADVIDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPL0</accession>
    <name>A0A518IPL0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_09970</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08589">
        <property type="entry name" value="PI-PLCc_SaPLC1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032075">
        <property type="entry name" value="PI-PLC-C1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16670">
        <property type="entry name" value="PI-PLC-C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="SSF51695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="375" mass="41765" checksum="41317029FE080221" modified="2019-10-16" version="1">MAKSPMFSRFNRFVLVTACLFANRPVDVLADELRMNQIQVIGTHNSYRQQPHPALLTLIKTTAPEVAQTLEYSHRPLPEQFSDFGIRQIELDLFNDSKGGLFASPRGLALAAIADAENIAPYDPSGAMKQPGLKVLHVQDVDFASSVPTFTLAMETLKTWSDEHPRHVPIMVLLELKQDRPTPLLTQPLPFDSVALDAVDQEIRSIFPNTHLVTPDTIRGDHPNLRAAISADGWPTLDDCRGKIVFAMDNGGRLTRDYMADHPNLVGRVMFVDLGPDHPDSVFRKLNNPIRQFDEIQAAVRSGCLVRTRADADTREARDNDYSRAEKAFSSGAHFVSTDYPYPDPTKSSYRVRLADDAVARTNPLLAPSIEPIDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPW4</accession>
    <name>A0A518IPW4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Xaa-Pro dipeptidase</fullName>
            <ecNumber evidence="5">3.4.13.9</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">pepQ</name>
        <name evidence="5" type="ORF">Mal33_10930</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase M24B family.</text>
    </comment>
    <dbReference type="EC" id="3.4.13.9" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102009">
        <property type="term" value="F:proline dipeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001131">
        <property type="entry name" value="Peptidase_M24B_aminopep-P_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="SSF55920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00491">
        <property type="entry name" value="PROLINE_PEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0224">Dipeptidase</keyword>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M24" evidence="4">
        <location>
            <begin position="136"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV55124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="377" mass="40482" checksum="5741BA849598C069" modified="2019-10-16" version="1">MQTTTLLAGIPAENASLFHRMPLSVGDPAAWIQVDDETTVIVRDIEVDRARRQLTANHFGSPGEYAPAGGLSPDRATATAQAVAEFLARKKIASIQTDRTLPFIFAWHIQQAGIEIAYNADLGVIDRRSKSDRELECLQTAQEMTQRAMELACRTIAASTANASGQLVHEGELLTSERVKAIAAQFFLEHNFAMEHGSIVATAPEVADCHHGGAGPLRTEVPIVVDLFPRDLSSRYWGDCTRTVVHGQASEEVKHMHAAVVQAKAAATAALRVGNTGDAVHQASTDVLLDRGYPLSRGTVTDHPSIQHGTGHGIGLEIHEPILLDDGGPEILPNEVLTIEPGLYGRNVGGVRVEDMVAATTDGPVVFGTLHQGLDWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPZ9</accession>
    <name>A0A518IPZ9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF559 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_11190</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007569">
        <property type="entry name" value="DUF559"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04480">
        <property type="entry name" value="DUF559"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF559" evidence="1">
        <location>
            <begin position="10"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="141" mass="16187" checksum="645CE1FC8EC9D6CB" modified="2019-10-16" version="1">MAEDQSDDNVSRARSLRQTQTVSEGVLWSVLRAKQLCGLKFRRQHLIGPWIVDFACPQKMLVVEVDGVYHDGVVDEDLRRQQHLRSLGWQTIRFTDKEVEEDAEAVARAIACKLNLPYEFKNRKATGAGMKSVNHPKQRRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQ22</accession>
    <name>A0A518IQ22_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Outer membrane porin HofQ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_11650</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial secretin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004846">
        <property type="entry name" value="T2SS/T3SS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004845">
        <property type="entry name" value="T2SS_GspD_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00263">
        <property type="entry name" value="Secretin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00875">
        <property type="entry name" value="T2SP_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021768193" evidence="4">
        <location>
            <begin position="31"/>
            <end position="1176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1049"/>
            <end position="1089"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="459"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1049"/>
            <end position="1063"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU004003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV55195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1176" mass="127491" checksum="4EA3B5193718AE79" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQ80</accession>
    <name>A0A518IQ80_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SQHop_cyclase_C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_12260</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032696">
        <property type="entry name" value="SQ_cyclase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008930">
        <property type="entry name" value="Terpenoid_cyclase/PrenylTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13243">
        <property type="entry name" value="SQHop_cyclase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48239">
        <property type="entry name" value="SSF48239"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021816266" description="SQHop_cyclase_C domain-containing protein" evidence="1">
        <location>
            <begin position="30"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="domain" description="SQHop_cyclase_C" evidence="2">
        <location>
            <begin position="56"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="387" mass="42108" checksum="83314D2AC8AB2BA5" modified="2019-10-16" version="1" precursor="true">MYQRWKFRHARRLFVTAALVAVTAGSAVAQPAAEGTKSETVSKSEALRREIVDKGLAYLAKQGQSDAGTFSDKVGPGVTALALTSALRNGRTAKDPMVAAGLKALEGFVKPDGGIYGNGRLRNYETCVAMVCFSEANSGGQYNEILKRAKDFVTGIQYGQGKRDPSDPWYGGVGYGGDGRPDLSNTGYFIEALRAAEGEPNDPAIQRALVFISRCQNLNSKHNDTQFAGKVDDGGFYYEIPTTKIDPSTSDERFTPNGGLRSYGSMSYNGLKSMIYAGLTTTDPRVQAAVQWITDHYDVENNPGMGSAGLYYYYHTFAAALQTSGMKTVKDADGKSHDWRSDLIAELAERQQPDGSWSNDNRRWFESDKNLATSFALMALSYCAPAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQ93</accession>
    <name>A0A518IQ93_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_12270</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="259" mass="28382" checksum="2F7022000FA694F8" modified="2019-10-16" version="1">MKSFQQTISMSSSLRSSKWNCLYAIQLATLAAMLAWTVFDPQFEPLVDALRRGSDSPIAALRSANVMFGAWRPSLFFVVIGLACVSLVGLFLGMLKGTVASRPVRSLRSLLMLTAVVALWCGLVTNHASLAWQGKRLRLVARVAELETIARPLRSDWPKEDGELPRIGPFMAYPFGDPTTMILLAPPTVSGGEICIAAIERCDDGAIKLQLGGSKAADWVEWHPESSEPESFVGGLQDSHHLRSHLRLGSGWFLVRYDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQL7</accession>
    <name>A0A518IQL7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Isoprenylcysteine carboxyl methyltransferase (ICMT) family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Mal33_13580</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007318">
        <property type="entry name" value="Phopholipid_MeTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04191">
        <property type="entry name" value="PEMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="45"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="106"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="186"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="216"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV55387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="253" mass="28962" checksum="B60BA1BC4BB1F3F7" modified="2019-10-16" version="1">MPLREEFVRSGSWLFRWRSYLPFVFLPLILVAAMRYPVIESHPNLHFAWSLLSLCVSLLGLAIRCHVIGHAADGTSGRNTKSQVAESLNTTGFYSVVRHPLYVGNFLIALGIVMHSLAPWLVVIYIMAFALYYERIMFAEEAFLRRKFGRDFMAWSTQTPAFLLRLRQWKKAEVPMDFPKVIRAESAAVAVIAFAFPALEFVMHHATEGSVAIENSWYALLASGVVLYAVARVMKRQLRRWLKYERILYAAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQM1</accession>
    <name>A0A518IQM1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Macrolide export ATP-binding/permease protein MacB</fullName>
            <ecNumber evidence="9">3.6.3.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">macB_2</name>
        <name evidence="9" type="ORF">Mal33_13560</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="3.6.3.-" evidence="9"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="285"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="337"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="371"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="8">
        <location>
            <begin position="19"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="7">
        <location>
            <begin position="313"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV55385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="409" mass="42775" checksum="A1A23A8BD6AC36B2" modified="2019-10-16" version="1">MKLRHLIWKELWQRPTPMLTSLLAVTLGVTALVAIQNITVFSERKIAGDMESLGANVLVLPPSVTLQDYYGADMHGHTMPEEYVTRLALARLPGVENLAPKLCVEAKVDTIPVTLTGILPKSEFQAKASWQGLGMLGNAVGSDRGCCATAADTGEADNDPNSLATTRTIAELGDRDVILGRDLASQLGAKTGDTLPLLGEDFTVLTVLPSTGTIDDGRMFAHLHSVQDLSGAGPVVNVIEIMACCEDAAGGLISNLAAELPETRIVTIAQVVQTQIAVNGLMSRLSWVFLSILLLVGGASIASVMYANVTERRKEIGTLMAIGASRNFVTRMFLGKAAVLGLAGGAAGFVVGTIVASVLGPQLLGIHVRPMPVLLGVGIATATIVAVLASLLPARRAAGLDPCLVFNDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQS4</accession>
    <name>A0A518IQS4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Mal33_14110</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022791">
        <property type="entry name" value="L-PG_synthase/AglD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03706">
        <property type="entry name" value="LPG_synthase_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021969354" evidence="7">
        <location>
            <begin position="26"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="78"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="151"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="182"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="229"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="270"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="310"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV55438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="358" mass="38187" checksum="9FC94E4BA4247DDD" modified="2019-10-16" version="1" precursor="true">MLLRIAKFAIALAVVVGLAHTIRSAAGELAEHRDRIRGEIADLDQQLESATDPAARADLQAKRERWVSQQPRLAAIDWWRVAAAAAVYLASLFPAALFFHQVLRHMKQHPRLGDAVRAHILGHMGKYVPGKAMVVVLRTGAIAGPNVRAGVAVVAAFIETLLMMAVGGTVAGVFVVCLRMPTGITLLAIGLAACAAVPTLPSLFRFVVRKISESRFGSDKGLDDAGIDWRLIGCGWGWMLLMWTAIGWSFALLIQATPGAMVDAFTWQDYMLATAAIALAMVAGFISLLPGGAGVRELVLSTLLAPRFGLVPALVAAILARLVFLAVEVGIGGLLWTTRGRTTPGDRSRCDTEDLPTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQV7</accession>
    <name>A0A518IQV7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_14530</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="101" mass="10985" checksum="FC3BAB7B1883FE7D" modified="2019-10-16" version="1">MSYDDGYNDEPQFDFENLSWVEGLESLSGCVQEGFSAFTDHAEEFERCDDPRAKRVAVLLRELADAAGVIARNGKAVAAMVQAAGDEWHAENGEGSPGDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQW6</accession>
    <name>A0A518IQW6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">O-acetylserine sulfhydrylase</fullName>
            <ecNumber evidence="6">2.5.1.47</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">cysK1</name>
        <name evidence="6" type="ORF">Mal33_14640</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 3">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="2.5.1.47" evidence="6"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004124">
        <property type="term" value="F:cysteine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006535">
        <property type="term" value="P:cysteine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005856">
        <property type="entry name" value="Cys_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005859">
        <property type="entry name" value="CysK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01139">
        <property type="entry name" value="cysK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01136">
        <property type="entry name" value="cysKM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PALP" evidence="5">
        <location>
            <begin position="11"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="3">
        <location>
            <begin position="181"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="269"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="4">
        <location>
            <position position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR605856-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR605856-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV55488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="311" mass="32933" checksum="8A09BC25D2596FA8" modified="2019-10-16" version="1">MPRGKTYANASQAIGDTPMIQINRLIPGDQATVFAKCEFFQPLNSVKDRIGVAMVEAAEKAGILNSETHIIEPTSGNTGIALAFVCAAKGYKLTLTMPESMSVERRALLRAMGANLVLTPAAEGMKGAINQAAELVEKGDNAWMPQQFENPANPAIHEATTGPEIWEDSGHDIDVLIAGVGTGGTITGVSRYLKSVNPSFKAIAVEPKHSPVISGGAPGKHRIQGIGAGFIPGNLDMSVVDDVVLVDDEDAFETARQLAKQEGIMAGISSGANMWAAQQIAARPEFKGKRIVTVMCSLGERYLSTPLFSDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQZ2</accession>
    <name>A0A518IQZ2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Amino_oxidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_14660</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amino_oxidase" evidence="1">
        <location>
            <begin position="25"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="476" mass="53995" checksum="5BEF142517B3D1A4" modified="2019-10-16" version="1">MTTANSPTDPPREDVYDTIIIGAGMSGLAAGIRLAYFDQRVCILEKHYTIGGLNSFYRQNGRDYDVGLHAITNFTEKGSKKGPLAKLLRQLRFRWDDFQLSPAIGSAIRFPDVELNFGNDIKLLEADIAKQFPHQKDNFQKLLARLLDYDDLDEASFNISTRQVLEETITDPLLIEMLLCPLMWYGNARQQDMDFGQFCIMFRACYMEGFARPFKGVRLILKNLVRKFRGLGGELKLRSGVDRIHVEGDRAVGVVLDDGTEIRGKRILSSAGQIETMRLCDDITQVDVARAGQLSFIESISILDRQPKQIGFDRTILFYNDSPRFHWERPEDTLCDPRTGVVCSPNNYLYDDADGELPDGVIRLTTLANHDRWCGLSEEEYRRQKTIQYDEAIDAAVRFMPDFRRHVIDTDVFTPKTIRRFTWHDNGAIYGAPEKQLDGQTHLPNLFLCGTDQGFVGIVGAIVSGISMANRHCLTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IR46</accession>
    <name>A0A518IR46_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Flagellar protein FliS</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Mal33_15360</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FliS family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044780">
        <property type="term" value="P:bacterial-type flagellum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003713">
        <property type="entry name" value="FliS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036584">
        <property type="entry name" value="FliS_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02561">
        <property type="entry name" value="FliS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101116">
        <property type="entry name" value="SSF101116"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1005">Bacterial flagellum biogenesis</keyword>
    <keyword evidence="6" id="KW-0966">Cell projection</keyword>
    <keyword evidence="5" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6" id="KW-0969">Cilium</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0282">Flagellum</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV55559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="146" mass="16088" checksum="D3A69012366B4A54" modified="2019-10-16" version="1">MDYRRAGNDVMETEVLTASPAKLRRMTVEFALRNVNQAIEQAAANGGVQKSEATLNLRDALTELLGGIRPSEESLSKQVADMYVFLLQWLTAAELDGDREKLVDIGRVLEIELDTWNQVVTTTISESSYRSAGGDDDSLDSICFDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IR99</accession>
    <name>A0A518IR99_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">O-Antigen ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_15950</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007016">
        <property type="entry name" value="O-antigen_ligase-related"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04932">
        <property type="entry name" value="Wzy_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="2 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="92"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="126"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="149"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="189"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="212"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="251"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="352"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="384"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="413"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV55618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="436" mass="47763" checksum="A8AA82AE6F2FE4A4" modified="2019-10-16" version="1">MSLALTSSATARRPSFDRLLMFWVPVIVLAVLVIRNDARMAYAQSANGAAVEAADLAENAGTGTRERQLLFLALGATGGMLLWRDQRTNRRPIYWPIMLLLGLLFAYGCCSVVWSDSPFLTVKRMIVLGCLALGAIGIGKVWSTRDFCLALIGWTLLFVLISVAAELANGVFLRGGDYRFSGVFHPNKQVFFCAFLFLCSSCMYQSERKRIYLAIAIFALIAVILTKSRTGTAACLLAGAWLWWSYLPRNWIVNLAVAGSILFSIGLIGLGASGEEVSLLSAARMGREDELSDPTKLTGRLPIWTETLSAFINQPLLGFGYGAFWSPERIRYFESQNGWAFSHAHSIYIESAVNWGLLGVFIMLMIVVATVRRAKYLLRTHERLAGRWMIALLILAAIAGLAESAFVADGFEAIVLCASIGLVACHGPVPPARGMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRB8</accession>
    <name>A0A518IRB8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Auracyanin-A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Mal33_16090</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000923">
        <property type="entry name" value="BlueCu_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028871">
        <property type="entry name" value="BlueCu_1_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002327">
        <property type="entry name" value="Cyt_c_1A/1B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013427">
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
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    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
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        <location>
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            <end position="21"/>
        </location>
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        <location>
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            <end position="629"/>
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        <location>
            <begin position="486"/>
            <end position="625"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV55631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="629" mass="68868" checksum="6E3B9115ED1D352A" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRD6</accession>
    <name>A0A518IRD6_9BACT</name>
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        <submittedName>
            <fullName evidence="2">Leucine Rich repeats (2 copies)</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">Mal33_16440</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022176116" evidence="1">
        <location>
            <begin position="23"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="300" mass="32930" checksum="17F0ABE7BED55479" modified="2019-10-16" version="1" precursor="true">MKFHCLTMLAVVSLAQSSVLHADTEVATAQGLEALGATVVLEGDRVVELSFRDSKRLGNEQWRAIGSLTHLKKLTAYGGAKGLNDETVGFLVGLQELESLSLDGAQLSDGGLAKLAELKRLKRVSFFHLSFRKEGFTGEGFSAWTELPDLESLTVAGMSMGDDGFRAIATLTNLRQLRTWHTYRTEASNAEIAKLPRLTTLKLGQRLPQRGNAPLSLSDASLETLTQIKTLETLEIGEADFHLPALRQLAKLPRLKQLKIDRTYLSEADIDALKSALPGVQIGFEPLTEDQRKKLDAYLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRG2</accession>
    <name>A0A518IRG2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_16480</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="334"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="711" mass="80155" checksum="9C8A2D66E4270F7F" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRG3</accession>
    <name>A0A518IRG3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Arylsulfatase</fullName>
            <ecNumber evidence="4">3.1.6.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">atsA_11</name>
        <name evidence="4" type="ORF">Mal33_16430</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="PTM">
        <text evidence="1">The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.</text>
    </comment>
    <dbReference type="EC" id="3.1.6.1" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004065">
        <property type="term" value="F:arylsulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
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    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022087787" evidence="2">
        <location>
            <begin position="22"/>
            <end position="462"/>
        </location>
    </feature>
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        <location>
            <begin position="29"/>
            <end position="355"/>
        </location>
    </feature>
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        <location>
            <position position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR600917-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV55664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="462" mass="51448" checksum="997F595A33598C35" modified="2019-10-16" version="1" precursor="true">MKTRPLFLLLTLWIVPLAAHAATADQPHPNIVYILLDDAGYGDLSCYGQKKFETPNIDRLAAEGMKFTQHYSGSTVCAPTRCCLMTGVHTGHAYVRGNREIKPEGQAPMPADIVTLPRLLSAAGYETGAFGKWGLGGPGSASDPAEHFDLFYGYNCQREAHNYYPDHLWKNRQRVPLDGKTYTATMIGDEGLDFIRENKDQPFFAFFPVAIPHAAMHAPESYIAPFREKFPEFENKIGKYAGPEVKNPIAAFAGMMTLVDEQVGQIIALLKELDLDERTIVMLSSDNGPHREGGHDPDFFDSNGPFRGYKRDLYEGGIRAPLIARWPGKISPGSTSDLISAHWDMLPTFCELAGAKTPNGIDGISLVPTLLGDDDKQQPHEFMYWEFHERGGKRAVRFGDWKAVQLNLNKKQRGEVELYHLPSDRGEQKNVAAEHPELVAKAKAIMLSAHQPSEHWKFKGGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRJ1</accession>
    <name>A0A518IRJ1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_16800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="192"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="248"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="289" mass="31535" checksum="23D521CDBD1263ED" modified="2019-10-16" version="1">MTILRRIRHALFASMAAFLLAILFVPTGEPRTVWTINDADAPPQLVIASGIASAPIHSPSRLPKLLTARLRWRLLMTQHYADQDINRQFRQAVDAVEAAGDEASTSSEAAMTLTSFRQPVEGQAEETQSSESPVDDDSPDAEASHFMTGHQFWTRQHKRAAAAYDELLSLDKPAVTASPLTTLPGLPTRGGLLLAICCGLLGGLTMASVDAFAYRKQTPPESNLDATLHLPASWFRVRRTPPQRLAHGLRTACIAWIVVAGLLLATSARKEMGLQRLMNWPLAELADLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRT2</accession>
    <name>A0A518IRT2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_17630</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="82" mass="8825" checksum="EF2166CBCACBA0AA" modified="2019-10-16" version="1">MTHRFVQPCPTCGRKLEIGIELLGRAVACQHCLAEFTAADPTSTQSILDDDSALLARVDQALQRADNLLTTNNNADANLTAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRU3</accession>
    <name>A0A518IRU3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_17960</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="370" mass="40114" checksum="0F2035DB3B9FDBAE" modified="2019-10-16" version="1">MHENWPLVWLYLTSCLFSSSIARSSAPKREIFLAAPRSARFRCFLQFVVAITLLFSGSWAAAADAVWYLPPAASSVGQTGWLPQPLRKLSGTIESFQQGKLQIVVADASSVEGLARRELDDDRIVWIQVDWSGEGAEVQQAFEDFNNRQFAACLKPMGEYVKRAKPRWRQLIAYGYLMNAAAAVDKHSAALAIAAGFHAAAPPSCFYSLLPIAWTRPPINAARDQAAVAGLQHADPAVRVIAASWLLTGTNRQRADAVLARASNDPTDPLLARLADAVRWRTAAGPEIAASLATWERKVDQLPIAVQAGPMAAIADRLQASGRGEEALAWWLSVAELGKQPGELADEAAAKARQLMETMAEQAAADQSNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISC2</accession>
    <name>A0A518ISC2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">1,4-dihydroxy-6-naphtoate synthase</fullName>
            <ecNumber evidence="3">4.1.-.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Menaquinone biosynthetic enzyme MqnD</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 4" type="primary">mqnD</name>
        <name evidence="4" type="ORF">Mal33_19760</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 3">Quinol/quinone metabolism; menaquinone biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the MqnA/MqnD family. MqnD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="4.1.-.-" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00079"/>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016830">
        <property type="term" value="F:carbon-carbon lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009234">
        <property type="term" value="P:menaquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00996">
        <property type="entry name" value="MqnD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003773">
        <property type="entry name" value="Menaquinone_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030869">
        <property type="entry name" value="MqnD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37167">
        <property type="entry name" value="PTHR37167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02621">
        <property type="entry name" value="VitK2_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0474">Menaquinone biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="3">
        <location>
            <begin position="109"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV55997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="278" mass="30529" checksum="2863889435C0AE62" modified="2019-10-16" version="1">MKIRLGISTCPNDTFTFHALMERLVDWRGLDFEIELLDIQQLNDRLFAGDFDVAKTSFHAALLLADQTVVLPSGSALGFGVGPLLLSARAGQVPDSLSQTTLCPGRHTTATLLFQLFYPQKTELQQVVFSQIMPMLRRGEADFGVCIHEGRFTWQSEGLGLVEDLGTRWESETGCPLPLGGLVARRSLPDETLARVQGVIHDSLCFAMADRNAAIPTMRRYAQEFNDEVLMQHVDLYVNDWTVDLGPVGANALSQLSQRAAASGILPSGLEPLQVWGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISE9</accession>
    <name>A0A518ISE9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_19940</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011463">
        <property type="entry name" value="DUF1569"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07606">
        <property type="entry name" value="DUF1569"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="154" mass="17572" checksum="25DF880C24261E1D" modified="2019-10-16" version="1">MKRRTLDLHNAAEVIADIEHLRAVGYTKTKRWNLTQVCQHLDSTMTGGMDGFGFRLPWILRRTVVKWGFGYALKKRKLLSGTPTLPVLQPPASSDRDDNDVIDHCIATIRRAGEFNGSLKEYALLDGLSPDDWREFMWIHAAHHLSFLVPDEES</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISI5</accession>
    <name>A0A518ISI5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional activator RfaH</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_20360</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031564">
        <property type="term" value="P:transcription antitermination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.940">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005824">
        <property type="entry name" value="KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006645">
        <property type="entry name" value="NGN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036735">
        <property type="entry name" value="NGN_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043425">
        <property type="entry name" value="NusG-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30265">
        <property type="entry name" value="PTHR30265"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00467">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02357">
        <property type="entry name" value="NusG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00739">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82679">
        <property type="entry name" value="SSF82679"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0889">Transcription antitermination</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="KOW" evidence="4">
        <location>
            <begin position="130"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV56057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="190" mass="21389" checksum="7B15D00789791DCF" modified="2019-10-16" version="1">MPILGEEPDMFPETILELPDEPDTQWWAMYTRSRQEKQLMRKLRELEVGHYSPVISRRYKSPAGRLRTTHLPLFANYVFVRGTGESRYQAVSTGCVSRCIDIADPTQLVTDLQQIHALIETGAALAPEERLEPGDLVRVKSGPFNGFEGTVVQRDGQRRLIVAVRFMNQGASAVLDDCQLEFLGKSTPAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISI8</accession>
    <name>A0A518ISI8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_20370</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022069270" evidence="2">
        <location>
            <begin position="26"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="182" mass="19029" checksum="20811650F4CA2C20" modified="2019-10-16" version="1" precursor="true">MRHLTSLCVGLLCGVVVCLNLGCPAASTTTDAPPTLSDDHGHSHGDHAAPETLAEAVESIDHMADEIQESFAADDPDGAHGPLHDIGSVLQTAGLMVAKSDLSDEQKQGASEALKKLIDAYGKVDAKMHGDEGVDYADVSAEITAAVEALQTATGIKVEHGHDHDHAEGHDHADDHDHAEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISM1</accession>
    <name>A0A518ISM1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_20220</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="15"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="38"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="265" mass="29345" checksum="71D5958CC1CC2A1B" modified="2019-10-16" version="1">MGRVGETIHTINTTVRTFLMVCVAGILGSAGYVTYDMFDAERRKLAETESALQSAQVDLENASVEIAQQAKTITRMETAMQLLKVDQRLARLEVISQQPQLASDMVSTTVRFTELSPDGNPIGKPKVFTIDGDVVYIDNWVVKFEDKFVESADIARGTSLTLFRRVFGEHQTPNDGFVIDEVGSMPQAYLRGGEPNEFEQEIWSKFWEFANDRKLAAEKGIRAAHGEAVSVKTEAGKSYLIELRASGGLSIYPEDRPVDALGEKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISN4</accession>
    <name>A0A518ISN4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Aquaporin Z</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">aqpZ2</name>
        <name evidence="10" type="synonym">aqpZ</name>
        <name evidence="11" type="ORF">Mal33_20810</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 10">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Cell membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="10">Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the MIP/aquaporin (TC 1.A.8) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015250">
        <property type="term" value="F:water channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00333">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1080.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01146">
        <property type="entry name" value="Aquaporin_Z"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023271">
        <property type="entry name" value="Aquaporin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034294">
        <property type="entry name" value="Aquaporin_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023743">
        <property type="entry name" value="Aquaporin_Z"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000425">
        <property type="entry name" value="MIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022357">
        <property type="entry name" value="MIP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19139">
        <property type="entry name" value="PTHR19139"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00230">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00783">
        <property type="entry name" value="MINTRINSICP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81338">
        <property type="entry name" value="SSF81338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00861">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00221">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="5 10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0677">Repeat</keyword>
    <keyword evidence="7 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="45"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="92"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="143"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="175"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="219"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="NPA 1" evidence="10">
        <location>
            <begin position="74"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="NPA 2" evidence="10">
        <location>
            <begin position="200"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="site" description="Involved in tetramerization or stability of the tetramer" evidence="10">
        <location>
            <position position="23"/>
        </location>
    </feature>
    <feature type="site" description="Selectivity filter" evidence="10">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <feature type="site" description="Selectivity filter" evidence="10">
        <location>
            <position position="188"/>
        </location>
    </feature>
    <feature type="site" description="Selectivity filter" evidence="10">
        <location>
            <position position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QDV56102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="248" mass="25062" checksum="A723DA81591E0587" modified="2019-10-16" version="1">MASIGTRSAAEFFGTFWLVFGGCGSAVLAAKVITPEVDTPINIGIGLVGVSLAFGLTVLTMAYAIGHISGCHLNPAVTVGLTVGGRSKGADLIPYVIAQVLGAIAGAGTLYMIASGKEGFAINNADAGAFATNGFGAISPGGYSMLACLVAEIVLTAFFLFIIMGATDKRAPAGFAPLAIGLGLTLIHLIGIPVTNLSVNPARSTGPALFVGGMQLTQLWFFWIAPIAGGVLGALIYQAIAKEETEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISP0</accession>
    <name>A0A518ISP0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_20870</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="69" mass="7715" checksum="F255693F64CF7EDF" modified="2019-10-16" version="1">MADRTLTAVDPGFLGVLAGGHCEVLTILTLVRSFSLDFCLDPNRYYPHNQNFCVIRRRISMGRQIGNSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISS8</accession>
    <name>A0A518ISS8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_21090</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="235" mass="25948" checksum="FF1C4DCE151BD52C" modified="2019-10-16" version="1">MNTQNNTDPTNAPQATAEPSGCAAWAPALIAGAALLGMLFFISCAGGTYYLFQQRGEFALRTIDGTLIPLIEQSRLEPDEKQATIAQLREFIKRGRSGELEDWQVAGVMQRLVRAPIISWGDLQYVGSVIAQRDSFSDDEKVEFLGELSRLQRGAELDKVTQFDMADIFEPISSPADHESGYSLNQEFSDEALREFIARAGLVADRAEVPEKTYDVKLVSIIQRQIQAGIKSGMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IST0</accession>
    <name>A0A518IST0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 5">Thymidylate synthase</fullName>
            <shortName evidence="5">TS</shortName>
            <shortName evidence="5">TSase</shortName>
            <ecNumber evidence="1 5">2.1.1.45</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 8" type="primary">thyA</name>
        <name evidence="8" type="ORF">Mal33_21270</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + dUMP = 7,8-dihydrofolate + dTMP</text>
            <dbReference type="Rhea" id="RHEA:12104"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:57451"/>
            <dbReference type="ChEBI" id="CHEBI:63528"/>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
            <dbReference type="EC" id="2.1.1.45"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Pyrimidine metabolism; dTTP biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.45" evidence="1 5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00575"/>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004799">
        <property type="term" value="F:thymidylate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006231">
        <property type="term" value="P:dTMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006235">
        <property type="term" value="P:dTTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00351">
        <property type="entry name" value="TS_Pyrimidine_HMase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.572.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00008">
        <property type="entry name" value="Thymidy_synth_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045097">
        <property type="entry name" value="Thymidate_synth/dCMP_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023451">
        <property type="entry name" value="Thymidate_synth/dCMP_Mease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036926">
        <property type="entry name" value="Thymidate_synth/dCMP_Mease_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000398">
        <property type="entry name" value="Thymidylate_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020940">
        <property type="entry name" value="Thymidylate_synthase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11548">
        <property type="entry name" value="PTHR11548"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00303">
        <property type="entry name" value="Thymidylat_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00108">
        <property type="entry name" value="THYMDSNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55831">
        <property type="entry name" value="SSF55831"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03284">
        <property type="entry name" value="thym_sym"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00091">
        <property type="entry name" value="THYMIDYLATE_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4 5" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thymidylat_synt" evidence="7">
        <location>
            <begin position="2"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="146"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="5">
        <location>
            <position position="146"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="21"/>
        </location>
        <ligand>
            <name>dUMP</name>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="126"/>
            <end position="127"/>
        </location>
        <ligand>
            <name>dUMP</name>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="166"/>
            <end position="169"/>
        </location>
        <ligand>
            <name>dUMP</name>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>dUMP</name>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="207"/>
            <end position="209"/>
        </location>
        <ligand>
            <name>dUMP</name>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="263"/>
        </location>
        <ligand>
            <name>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV56148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="264" mass="30115" checksum="2976E682ABED5090" modified="2019-10-16" version="1">MKTYLELLNQIIEHGTDRPDRTGTGTRSQFGAQMRFDLAAGFPLLTTKRLHLRSILYELLWFLRGDTNIAWLKENGVSIWDEWADENGDLGPVYGHQWRSWPAPDGGTIDQIAEVESQIRDNPNSRRLIVSAWNVAEVNNMALPPCHCLFQFYVADGRLSCQLYQRSADFFLGVPFNIASYALLTMMMARVTGLQPGDFVHTLGDVHLYHNHFEQARLQLSREPRPLPTMQISGDQKSLLDFKFEDFELIGYDPHPHIKAAVAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISV4</accession>
    <name>A0A518ISV4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sialidase</fullName>
            <ecNumber evidence="2">3.2.1.18</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">nedA_1</name>
        <name evidence="2" type="ORF">Mal33_21470</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.2.1.18" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052794">
        <property type="term" value="F:exo-alpha-(2-&gt;3)-sialidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052795">
        <property type="term" value="F:exo-alpha-(2-&gt;6)-sialidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052796">
        <property type="term" value="F:exo-alpha-(2-&gt;8)-sialidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008152">
        <property type="term" value="P:metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011040">
        <property type="entry name" value="Sialidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036278">
        <property type="entry name" value="Sialidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13088">
        <property type="entry name" value="BNR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50939">
        <property type="entry name" value="SSF50939"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sialidase" evidence="1">
        <location>
            <begin position="99"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="393" mass="44481" checksum="08DFD6DDCFAB5D1B" modified="2019-10-16" version="1">MLNRRNLIKAAAGWGGACALPGIPANSWAKSYGEDRPLLRPVFDQVICPETAEHPRNDHQTILPLDSDRLMLVWSEYYLNAAQPSQRGGNARIGDEVSCQISSMISSDRGRTWGDRRVLQPNEWKHNVKQSNLVRLSENELLMFYVGWDSATDRNVFRRRSFDNGQTWDAQVQISQPGWYCNNADRAIRLSTGRILLPAHGPYDPRYIGGTRYKGGDLHSFVYYSDDGFQTWKTSKNSMTAQGRGCHEPTIVELKDGSLYCLMRNTNKTQYASRSTDGGETWSTPEPTVLISPESPALLKRIPSTGDLMVIWNNVSSSSNWPRNPLSIAISDDEAKTWKHVQDIDNRNNFEVAYPSATFVDDEVLIAYYSRPTRGRVGSEVTLRIYKTDQLYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISW5</accession>
    <name>A0A518ISW5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_21490</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011453">
        <property type="entry name" value="DUF1559"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07596">
        <property type="entry name" value="SBP_bac_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="329" mass="35922" checksum="01F04D74B8AF1E7A" modified="2019-10-16" version="1">MLHQTCFPNQRLRRRGSRPVTSVRTMGFTLVELLVVIAIIGILVGLLLPAVQAAREAARRMQCTNNLKQLGLAVHNYADTFKVIPPLEVWKNGRTTNWGANVLLMPFIEQSALHEALNPQGDAIPNVSVQPLLATRIDGFICPSDPGPYLNFAFNDYGKANYLPSQGVFWVPYNDSGYTQACRLANITDGLSNTLLYGERFLGEQPFRSVGGIWAGRSRTGGNVQAHGRAAWPPNTPYAGDLDDISGTSDPLNTRTAYTSLDPGGVNITRCDGSVRFISENVDSLTSYPSSSSTNFFRLAAQAVSQPSDANRVWQNLFIPNDGNPVGDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISX6</accession>
    <name>A0A518ISX6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fructoselysine 3-epimerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_21690</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013022">
        <property type="entry name" value="Xyl_isomerase-like_TIM-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01261">
        <property type="entry name" value="AP_endonuc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="SSF51658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021856096" evidence="1">
        <location>
            <begin position="32"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="domain" description="AP_endonuc_2" evidence="2">
        <location>
            <begin position="58"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="299" mass="32614" checksum="0583CFF4490D714A" modified="2019-10-16" version="1" precursor="true">MSASFSFSRRDLLRTAAPVATAAMFAPSAFAWQSKSKILNTLKIGMVKIDGASLEERFRVVKEVGFDGIEMNSPGMDVAETKAAIKATGLVVDGTVCAGHWGIRHTSPDAATRAKALENLKIALRDTKAVGGDTVLLVVGKGEDGPEQEIWERSVENISKAVPLAEELNMKIAIENVWNQFLYDHDGDSNQSADKFVKYVDEFNSPAVGMQFDIGNHWKYGNTGDWIRTLGKRIVKLDSKGFSRANNRFTKIGEGDIDWKDVRAALTEIGFEGWCAAEVGGGGKERLAEVLANMKRTLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IT72</accession>
    <name>A0A518IT72_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">4-hydroxy-tetrahydrodipicolinate synthase</fullName>
            <ecNumber evidence="1">4.3.3.7</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">dapA_1</name>
        <name evidence="1" type="ORF">Mal33_22740</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="4.3.3.7" evidence="1"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008840">
        <property type="term" value="F:4-hydroxy-tetrahydrodipicolinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002220">
        <property type="entry name" value="DapA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00701">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01130">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="366" mass="40044" checksum="B37CF3C97070432A" modified="2019-10-16" version="1">MVIERRISRRTIIKATAAGGASVAAGSLFSASPLRGADDAAVADPKVRGPFPILSTPFTESGEVDYDVLAQQAKFVSWGGCPGMIWPQSGDSVDLLTTEEKMKGMEVLAKTTRDLPASLCLGVQGKDTAEMLAFAEHAEKLEPEAIISRSPDSGKSEEDLRQYWKALAAVARRPVILQTTGGVAYKGPLPSPELMIDLAREFPHFGYIKEEAGNVLARMKVSLAAMPPVRRVFSARGGFHWLEESRLGSEGVITERAVYADVLTRFWELQQSRDDPAALQDLFDKFTQMVRLKPGSLRGTNLYIWKKRGVFKNLLSRNYGPKKSIPAEPKLSEFKMSEAQIAEADAKFAALGPYLKTVTPDLDNPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITD7</accession>
    <name>A0A518ITD7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Xylose isomerase-like TIM barrel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_23290</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013022">
        <property type="entry name" value="Xyl_isomerase-like_TIM-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01261">
        <property type="entry name" value="AP_endonuc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="SSF51658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022154946" evidence="1">
        <location>
            <begin position="28"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="domain" description="AP_endonuc_2" evidence="2">
        <location>
            <begin position="109"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="303" mass="33308" checksum="63BD29B7171B7AF1" modified="2019-10-16" version="1" precursor="true">MQVSRRQFSATCAAAGAALALPQFARAANSGFQFRYLLGSCMYGYAPVAEILPEVAKTGSVALDIWPKAHGDQREQLDAMGEEAFATLLKQHNVPLGCITQYKLRPFGLQDEMRLAQRLGCSTIVTGGKGPKGLQGGELKRGVAKFVEQMKPHLAVAEETGVTIAIENHGNNLIESPDSLRWLIDLCPSDHLGIALAPYHLDQDSNLLAELILALGDRLSVFYAWQYGMGCMKKLPKRQELLQMPGRGELDFAPLVDALVETKFSGWTEIFMHPVPRGIPILESTDKVTTEINRSRAYLEDLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITJ8</accession>
    <name>A0A518ITJ8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_24060</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="265"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="374" mass="41940" checksum="CED8ADC163D58D87" modified="2019-10-16" version="1">MSEYQWIEFRAVDGPLDDASLEFMRQQSTRAEISRWSFTNEYHFGDFRGDVDQMMRRGYDVHVHYANFGIRRIAFRMPDGFPFADAIEPYLFEEGIYWEPDGSGTAGILTLEPEGDAGTWEWMEDVQNLASDLIPIREMLIVGDLRPLYIAHLAFNWDDDAIEPPVPAGLRDQHYALDRLRSFYEIDPDLLSVASEASPEQNKSASDDSMIDNWMASLSEAELAENLRRCLTEPKLAASQLLTTIRTQASEAPNLGTGERTLGQLREAASKIEAERLRIQLAEAAKRSAEQKAAAEKALEKQLASIAENPELTIGRIDSAISEKNRPAYQRAAKQLGLLAMACGKPMADAKADAIRQKYPTRSALSSELKKEGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITN0</accession>
    <name>A0A518ITN0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">pknB_10</name>
        <name evidence="10" type="ORF">Mal33_24390</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="361"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="422"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="461"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="49"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="78"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV56449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="490" mass="54490" checksum="932A810EFF7864D6" modified="2019-10-16" version="1">MADERNPSVDTSNSAAARDHHTTEHGYVTAHDPCVDRTLLLPGMHVDRFVIQQEVGRGGFGIVYKALDPNLGRHVAIKVPRADFLTTPTDRLYREAKIVATLEHEGIVRVYEAGTDSETSFIVSQLCEGPDLHTWMLDRANRLSFVQAAELIAQLADALSYAHRHGVLHRDVKPGNVLLFPLATPTSDDEPLPGHALPFQPRLTDFGLASMQSSDWAITRNSVAIGTPLYMAPECFARGDQTPGEPADIYGLGAVLFELLIGKPPVRGEHFGQLLHSITNEVREYPHQLDARVPIDLSIICNKCLRKDAEDRYASAGDLRDDLRRFLQGQPIDARVPTWRDRFAKWCQQPQRIRIAGASSFWFHLMLVPWLVGQLLLLGNMGAIPRDILVRSLIDAFWVSVVLHLPQVWLGYRLAKGSRWPFWPSAITSVLSLCVFAASAFSQQALFDYMYPSSVSKVATFSLLISAGSIVLGCYVLAIPAYLRSRRHAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITQ6</accession>
    <name>A0A518ITQ6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Divergent AAA domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_24620</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025831">
        <property type="entry name" value="RecG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038475">
        <property type="entry name" value="RecG_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007421">
        <property type="entry name" value="Schlafen_AlbA_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038461">
        <property type="entry name" value="Schlafen_AlbA_2_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04326">
        <property type="entry name" value="AlbA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13749">
        <property type="entry name" value="HATPase_c_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AlbA_2" evidence="2">
        <location>
            <begin position="20"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="HATPase_c_4" evidence="3">
        <location>
            <begin position="325"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="496"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="603"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="511"/>
            <end position="529"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV56472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="630" mass="70848" checksum="DB37188E1E159781" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITR2</accession>
    <name>A0A518ITR2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_24650</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="96" mass="10332" checksum="802849DAE1EF4BF7" modified="2019-10-16" version="1">MSLDFDKWADGLCDRLRAEITADVVKSLTPLVHAASQQPSLVDRHRQAELLGISVPKLDSLVREGVIPSKQVGTRRLFDPAAVIAAIPDTGGVSDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IU21</accession>
    <name>A0A518IU21_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Motility protein B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">motB</name>
        <name evidence="7" type="ORF">Mal33_25730</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MotB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07185">
        <property type="entry name" value="OmpA_C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025713">
        <property type="entry name" value="MotB_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006665">
        <property type="entry name" value="OmpA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036737">
        <property type="entry name" value="OmpA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13677">
        <property type="entry name" value="MotB_plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00691">
        <property type="entry name" value="OmpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103088">
        <property type="entry name" value="SSF103088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51123">
        <property type="entry name" value="OMPA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="16"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="domain" description="OmpA-like" evidence="6">
        <location>
            <begin position="113"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV56581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="259" mass="28373" checksum="81099156F3A3815E" modified="2019-10-16" version="1">MDDDGGGDDAAAIPEWVVTFGDMMSLLLTFFIMLVSLSEIKEEDKYQALVESMRQQFGHERSMESMSPGEAKPRETAFEVLATMGRAKRLDSHNGGVKAKAPVGEQPTVRIIRPGRLTAVGTVVFFPEGEAELGADAKAALDGIADELKGKPQKIEIRGHTSARTAAKAVSIRQPMNLAYSRAVQVYDYLVNHHQIDPRRCRIAAAADSEPMSVAADPAKQQQNPRVEVFLLDETVSDLIGTNVERQKNIIPESGQERQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IU81</accession>
    <name>A0A518IU81_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_26470</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="364" mass="40148" checksum="7358C702EE01C9E8" modified="2019-10-16" version="1">MEARFLRSLFVVATLLAVPAFGAGYRTQNFIVQASTPQFAKQVGDAAEQFRSQLAIDWLGSELPPWPAPCPIRVQDAPHLGAGGATEYTPTRRGVRDFRMSIQGSQIRIMDSVLPHEVTHTVLATHFGQPLPRWADEGASTTVEHHSERQRHEEMLREFLSNNRGIPMNQMFMMREYPSDILPLYAQGFSVSRFLIEQGGRRKFVDFVGETLQGSQWTHAVRRHYGYESLSELQDTWLAWVASGSGPVDAYVKNRGPAAADVAQVAAVAPAGNMSQPGDVTQIAAATPSPQRQGMQATLASADGSGWYMRRRQEVAAGEVADPEPSQSFNKKSIRDHGLARPQAMQTIAPQGVPWGPEQGTVWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUG6</accession>
    <name>A0A518IUG6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Cyclopropane-fatty-acyl-phospholipid synthase</fullName>
            <ecNumber evidence="1">2.1.1.79</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">cfa_2</name>
        <name evidence="1" type="ORF">Mal33_27320</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.1.1.79" evidence="1"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008825">
        <property type="term" value="F:cyclopropane-fatty-acyl-phospholipid synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="358" mass="41585" checksum="72DBD9F729C05939" modified="2019-10-16" version="1">MGQTEAIDPATDESTLQSFFGFVTRKAEAGWLPDPLLRAGIRRLLRSRLRDLHELADDSDCEAFLRATRPQPIAVVPEKANDQHYEVPAEFFRQVLGPRLKYSCCRWTEGILSLQQAEEQALRETCENAQLEDGMSILELGCGWGSLSLWMAEHYPNSQITAVSNSHSQREFITARAREAGLTNLQVLTVDINHFQPDDSFDRVVSVEMFEHMRNHRKLMDRIHDWLVPDGKLFVHIFCHKRTPYLFRSDGEQNWMGRYFFTGGMMPSENLLESVGSRLTLASKSRWSGMHYAKTSRAWLENHDRCSESLLPILKQTYGEDQAIMWQNRWRMFFMACEELFAFNGGNEWFVSHYLFER</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUM4</accession>
    <name>A0A518IUM4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cation efflux system protein CusC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">cusC_3</name>
        <name evidence="5" type="ORF">Mal33_27900</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010131">
        <property type="entry name" value="RND_efflux_OM_lipoprot_NodT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01845">
        <property type="entry name" value="outer_NodT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0564">Palmitate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1134">Transmembrane beta strand</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="554"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="296"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="571"/>
            <end position="617"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV56791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="631" mass="69741" checksum="54084D33370E2D19" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUR1</accession>
    <name>A0A518IUR1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_28330</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="57"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="156"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="537"/>
            <end position="1060"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1132"/>
            <end position="1158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="537"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="647"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="733"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="777"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="835"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="875"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="898"/>
            <end position="918"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="948"/>
            <end position="964"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="998"/>
            <end position="1017"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1182" mass="123985" checksum="0F7270F89F966496" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUV1</accession>
    <name>A0A518IUV1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Dihydroorotate dehydrogenase</fullName>
            <shortName evidence="9">DHOD</shortName>
            <shortName evidence="9">DHODase</shortName>
            <shortName evidence="9">DHOdehase</shortName>
            <ecNumber evidence="9">1.3.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">pyrDB</name>
        <name evidence="9" type="synonym">pyrD</name>
        <name evidence="11" type="ORF">Mal33_28750</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the conversion of dihydroorotate to orotate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>(S)-dihydroorotate + A = AH2 + orotate</text>
            <dbReference type="Rhea" id="RHEA:18073"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:30839"/>
            <dbReference type="ChEBI" id="CHEBI:30864"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
        <text evidence="9">Binds 1 FMN per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Pyrimidine metabolism; UMP biosynthesis via de novo pathway.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.3.-.-" evidence="9"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00070"/>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004152">
        <property type="term" value="F:dihydroorotate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd04740">
        <property type="entry name" value="DHOD_1B_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00224">
        <property type="entry name" value="DHO_dh_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033888">
        <property type="entry name" value="DHOD_1B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005720">
        <property type="entry name" value="Dihydroorotate_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024920">
        <property type="entry name" value="Dihydroorotate_DH_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012135">
        <property type="entry name" value="Dihydroorotate_DH_1_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001295">
        <property type="entry name" value="Dihydroorotate_DH_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01180">
        <property type="entry name" value="DHO_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000164">
        <property type="entry name" value="DHO_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01037">
        <property type="entry name" value="pyrD_sub1_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00912">
        <property type="entry name" value="DHODEHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 9" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6 9" id="KW-0288">FMN</keyword>
    <keyword evidence="8 9 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7 9" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DHO_dh" evidence="10">
        <location>
            <begin position="1"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9">
        <location>
            <begin position="52"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9">
        <location>
            <begin position="174"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="9">
        <location>
            <position position="113"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="4"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="28"/>
            <end position="29"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="28"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="110"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="225"/>
            <end position="226"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="247"/>
            <end position="248"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QDV56874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="291" mass="30374" checksum="37377CBEDD66511B" modified="2019-10-16" version="1">MVASGTFGYAREMARLVDCSRLGGILPKTITAQPRVGNAPWRTVETSAGLLNSIGLDNDGIDAFMEHHLPYLASIGTSIIVSIAGRTEEEFVQLAHRVGQTGQIAAVELNVSCPNVSGGVDFGTDPDACHRLVAATRAGCDVPILAKLTPNVTRIADVACAAAEGGADGVCLINTVLGMAVDWRRRRPMLGNVMGGLSGPAIKPVALRCVQQVRSVTDVPIIGIGGIATIDDVMEFLVTGATAVQIGTANYYDPQVSTRLIDELPAALQELGAATVGEIVGTLDSTRRVDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUY2</accession>
    <name>A0A518IUY2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SMI1 / KNR4 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_28990</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018958">
        <property type="entry name" value="Knr4/Smi1-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037883">
        <property type="entry name" value="Knr4/Smi1-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09346">
        <property type="entry name" value="SMI1_KNR4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00860">
        <property type="entry name" value="SMI1_KNR4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160631">
        <property type="entry name" value="SSF160631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SMI1_KNR4" evidence="1">
        <location>
            <begin position="26"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="213" mass="23388" checksum="66442219DE9715B2" modified="2019-10-16" version="1">MQKTLDRVAKHLADAGIALNVELNPPATTGDVDTAQSRIGLALPPAYVDFVTQFANGLSLSWTTDDGPFGSFELEPVANSVGGALEMRDWRFYDDDAARDYGFPYTDDPDLALVTNKLMHNWIPLHAEGNGDNLSLDLNPEGFGNVVFDHHSWLDGGTGANGFLMASDFTSFFEAWSTVCFAQPKSLSWKSVLTDDGVDWASDQFDDRFRLTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IV34</accession>
    <name>A0A518IV34_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_29540</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="97" mass="11474" checksum="9CB6935A8CB57EA0" modified="2019-10-16" version="1">MDASKLKRGDWVIYRKQKSSTSPGARATDVHPTPGGDTYHYLVDKFWVVEAVLENQQILLRTRRGKQHTIDANDPRLRRASWWERLMYRSRFTTIEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IV75</accession>
    <name>A0A518IV75_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">UDP-3-O-acyl-N-acetylglucosamine deacetylase</fullName>
            <ecNumber evidence="4">3.5.1.108</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">lpxC</name>
        <name evidence="12" type="ORF">Mal33_29870</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a UDP-3-O-[(3R)-3-hydroxyacyl]-N-acetyl-alpha-D-glucosamine + H2O = a UDP-3-O-[(3R)-3-hydroxyacyl]-alpha-D-glucosamine + acetate</text>
            <dbReference type="Rhea" id="RHEA:67816"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:137740"/>
            <dbReference type="ChEBI" id="CHEBI:173225"/>
            <dbReference type="EC" id="3.5.1.108"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 2/6.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.108" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00359">
        <property type="reaction ID" value="UER00478"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008759">
        <property type="term" value="F:UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0103117">
        <property type="term" value="F:UDP-3-O-acyl-N-acetylglucosamine deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1700.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004463">
        <property type="entry name" value="UDP-acyl_GlcNac_deAcase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011334">
        <property type="entry name" value="UDP-acyl_GlcNac_deAcase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015870">
        <property type="entry name" value="UDP-acyl_N-AcGlcN_deAcase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33694">
        <property type="entry name" value="PTHR33694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03331">
        <property type="entry name" value="LpxC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00325">
        <property type="entry name" value="lpxC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0441">Lipid A biosynthesis</keyword>
    <keyword evidence="5" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QDV56986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="293" mass="31717" checksum="7DD8737DF58979C0" modified="2019-10-16" version="1">MTCQRVEHTIEAACQVTGRGYWSGQQVTVRFLPADPGSGIRFVRTDLPGCPSVPGLVGFRQSMSLRTVLSSDTGAVVSMVEHLMAALSALQIDNCEIQVDAEEMPGMDGSAAAFVDALNSTARVEQATTIRPYRVDRLLRIGSASNWIEASPSDSDSFEVEYRLDYGDDCPIRPQTAAFQVTPESFAKELAPARTFVTADQAKQLRASGVAGHVTNQDLLIFDDHGLVENSLHFENECARHKAMDLVGDLALAGFPLIGRFVSHRGGHELNASMAAELQQLSCRSMNGSRKTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IV92</accession>
    <name>A0A518IV92_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Macrolide export ATP-binding/permease protein MacB</fullName>
            <ecNumber evidence="9">3.6.3.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">macB_4</name>
        <name evidence="9" type="ORF">Mal33_30080</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="3.6.3.-" evidence="9"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="286"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="340"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="372"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="8">
        <location>
            <begin position="19"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="7">
        <location>
            <begin position="314"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV57007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="410" mass="42839" checksum="AB43B001F8286E0D" modified="2019-10-16" version="1">MQLKSMIWKELWQRPTPMLTSLLAVTLGVTALVAIQNITVFSERKIAGDMESLGANVLVLPPNVSLQDYYSADMHGHTMPEEYVTRLALARMAGVENLAPKLCVAADVDSIPVTLTGILPRSEFQAKSAWQGLGMLTNAVGTDAGCCAPKASVPSSGDNDPDSLATNRTIEELGDRDVILGRDIATQLGASVGDKLPLLGEEFKVLTILPSTGTIDDGRVFAHLHSVQDLSEAGPVVNVIEIMACCEEAAGGLIGKLSAELPDTRVITIAQVVETQIAVNGLMSRLSWVFFSILLLVGGASIASVMYANVTERRKEIGTLMALGASRGFVTKMFLGKATLLGLAGGVGGFAAGTILAAILGPQLLGVHVQPMPSLLGVGMATATIVAVLASLLPARRAAGVDPCLVFNDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVA9</accession>
    <name>A0A518IVA9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NADP-dependent fatty aldehyde dehydrogenase</fullName>
            <ecNumber evidence="3">1.2.1.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">aldH</name>
        <name evidence="3" type="ORF">Mal33_30200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.2.1.4" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033721">
        <property type="term" value="F:aldehyde dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07129">
        <property type="entry name" value="ALDH_KGSADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044151">
        <property type="entry name" value="ALDH_KGSADH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="2">
        <location>
            <begin position="27"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="533" mass="55664" checksum="C69E34FFD3D97F49" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVB5</accession>
    <name>A0A518IVB5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Peroxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_30270</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002105">
        <property type="entry name" value="Dockerin_1_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036439">
        <property type="entry name" value="Dockerin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019791">
        <property type="entry name" value="Haem_peroxidase_animal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037120">
        <property type="entry name" value="Haem_peroxidase_sf_animal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033764">
        <property type="entry name" value="Sdr_B"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03098">
        <property type="entry name" value="An_peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00404">
        <property type="entry name" value="Dockerin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17210">
        <property type="entry name" value="SdrD_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00457">
        <property type="entry name" value="ANPEROXIDASE"/>
    </dbReference>
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        <property type="entry name" value="SSF48113"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF63446"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50292">
        <property type="entry name" value="PEROXIDASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="SdrD_B" evidence="3">
        <location>
            <begin position="658"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="112"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="638"/>
            <end position="658"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV57026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="730" mass="80181" checksum="582E1CE99433F72E" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVN6</accession>
    <name>A0A518IVN6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Lipid A biosynthesis lauroyl acyltransferase</fullName>
            <ecNumber evidence="7">2.3.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">htrB</name>
        <name evidence="7" type="ORF">Mal33_31520</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.3.1.-" evidence="7"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009247">
        <property type="term" value="P:glycolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd07984">
        <property type="entry name" value="LPLAT_LABLAT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004960">
        <property type="entry name" value="LipA_acyltrans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30606">
        <property type="entry name" value="PTHR30606"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Lip_A_acyltrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV57151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="324" mass="37177" checksum="7AAAD70A60DB370D" modified="2019-10-16" version="1">MNLARKRIRRRVNKQTAIDFAVYLLVRTLFAVIQTLSVQRMQPVCNGLAYLVSDVLQIRRRIIDTNLRIASPNASDQQINETRRQMWAHLVMMACEIAWSRRRLHLSNWRQMLDFPTSGIFLRPFLEGRPMVLVSGHYGNFEIGGYATGLFGIPTMTVARPLDNRFLHRYITQFRGMHGQMLVDKEGSADIIQQHLESNGTLSLVADQFAGARGCWVNFFGKPTSCHKALALFTLANDAPMAVFYSRRTTGPMQFEIGCNGVADPREAGPELGGVTELTCWYNERLEKAIALSPEQYWWMHRRWRDVPEKIQRRMDRMAAKQAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVU3</accession>
    <name>A0A518IVU3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_32160</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="61" mass="6768" checksum="F6FB306DEC85D026" modified="2019-10-16" version="1">MLYFVLLEDEGYSLIKKIAGYHPLHGVRVITIAAADSDDDALRESRTINSRQTTESSLKSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVW8</accession>
    <name>A0A518IVW8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_32290</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08577">
        <property type="entry name" value="PI-PLCc_GDPD_SF_unchar3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039559">
        <property type="entry name" value="AIM6_PI-PLC-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="SSF51695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="291" mass="32047" checksum="98D7CC5D45345549" modified="2019-10-16" version="1">MTNNTTVSPLRFRGNSRLLVPAIAAAHLAGLLLLVGSVMLQIANADQPATEIEPLRQAHAHNDYLHTRPLLDALDHGFCSVEADVFLVDGELLVAHSRSELSPDRTLKRLYLDPLRERVQRGGGRVYPGGPVVTLLIDFKADGAATYAALDNLLSQYHDVFSVVRNGQRIEKAVNVVISGDRPFAAVASDEERFAGLDGRLSDLDSDMPAHLMPMISDRWGKHFKWRGEGEMSGEEQAKLAAIVAKAHAKERVLRFWAIPDTPRSWRAMQSAGVDLINTDDLKGLSQMLQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IW13</accession>
    <name>A0A518IW13_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Branched-chain-amino-acid aminotransferase</fullName>
            <ecNumber evidence="1">2.6.1.42</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ilvE_2</name>
        <name evidence="1" type="ORF">Mal33_32710</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.6.1.42" evidence="1"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052656">
        <property type="term" value="F:L-isoleucine transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052654">
        <property type="term" value="F:L-leucine transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052655">
        <property type="term" value="F:L-valine transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001544">
        <property type="entry name" value="Aminotrans_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036038">
        <property type="entry name" value="Aminotransferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043132">
        <property type="entry name" value="BCAT-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043131">
        <property type="entry name" value="BCAT-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01063">
        <property type="entry name" value="Aminotran_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56752">
        <property type="entry name" value="SSF56752"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="276" mass="29982" checksum="E90C3C4CE2BF6A98" modified="2019-10-16" version="1">MGFTDMSIWYRSGEWIDGEVALPVDDLGVFQGVIAVERLRTYSSRVFRLDDHLDRLRRTTSLLSIDAGPAIDAMPACIEELLRINAAPPDVGITLLITPGKLRDRTPTVIAHLAPLDLARLQRLQSEGEALVVTSVIQPPDESIPRAAKHRSRLHYYLAAEQSRQIDPSATAVLVDTDGSLTETASANILLVRDGCIYSAPPHRVLPGVSLGVVRQLADEAGIAWRDQPLEPAMFAAADEILLTGTGAGIWFGNNRSGPIYRQLAAAFRALTGESQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IW42</accession>
    <name>A0A518IW42_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Inner membrane protein YjdF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">yjdF</name>
        <name evidence="2" type="ORF">Mal33_33180</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014509">
        <property type="entry name" value="UCP020606"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09997">
        <property type="entry name" value="DUF2238"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF020606">
        <property type="entry name" value="UCP020606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="112"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="136"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="188"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="213" mass="23674" checksum="EB69BD19DE504BFB" modified="2019-10-16" version="1">MIRPASQRRLRIIGLIVTAAAIPLSFVAAPYPNELVLQHIPTAVGIGLLTVAVVRYHPSRSSYICCLTFLWLHIIGARWIYSFVPYDDAVKMITGHTISETFGWQRNHYDRLVHFASGALGMAPISHLLQSWCRIAPAAAAILAMACVLAIGAAYEILEWQIAMLFSPEMAESYNGQQGDIWDAQKDLALAWLGAVVVIPMIYRWNPTAQDLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWB3</accession>
    <name>A0A518IWB3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_33940</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="261"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="370" mass="41717" checksum="A03C4DCB27B9548D" modified="2019-10-16" version="1">MQYRRAAELSDLRRACRLAEQAGSWQELQRAAERWVALQPFNDQAIMHLATAKKSLEDWGGLVDAVEQLPVSNAYLVPSLAVAGDVAIDHLEDIERAERLFWAILAIDPRNEQAYQRLIFLYSMTLQKAKLQAVIRQAIERGAQPVEAGVYLTTMSALNFSDGLFRVAGWRAATPGHEPLEVAYAIYLARASGNESNRVLRMLDSQVPEYGTLDIARRMQERYPNNIELLSFWIDHAMERGEVEQVREALSRWQPELQDDYRYWRYLGWLQDMSGDLETSLSSYRKSLSIHPLDWRARNEMATLQRALGVDGAAANAELAAEGKELERMLKELPSASQLSTVNAAKLGEYARKCGDSVAERAFRRGAGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWE2</accession>
    <name>A0A518IWE2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">N5-carboxyaminoimidazole ribonucleotide synthase</fullName>
            <shortName evidence="3 5">N5-CAIR synthase</shortName>
            <ecNumber evidence="3 5">6.3.4.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3 5">5-(carboxyamino)imidazole ribonucleotide synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 5 7" type="primary">purK</name>
        <name evidence="7" type="ORF">Mal33_34210</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).</text>
    </comment>
    <comment type="function">
        <text evidence="5">Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 5">
            <text>5-amino-1-(5-phospho-beta-D-ribosyl)imidazole + ATP + hydrogencarbonate = 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole + ADP + 2 H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:19317"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58730"/>
            <dbReference type="ChEBI" id="CHEBI:137981"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.18"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 5">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate from 5-amino-1-(5-phospho-D-ribosyl)imidazole (N5-CAIR route): step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 5">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 5">Belongs to the PurK/PurT family.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.18" evidence="3 5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00942"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034028">
        <property type="term" value="F:5-(carboxyamino)imidazole ribonucleotide synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004638">
        <property type="term" value="F:phosphoribosylaminoimidazole carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01928">
        <property type="entry name" value="PurK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003135">
        <property type="entry name" value="ATP-grasp_carboxylate-amine"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029752">
        <property type="entry name" value="D-isomer_DH_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005875">
        <property type="entry name" value="PurK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040686">
        <property type="entry name" value="PurK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02222">
        <property type="entry name" value="ATP-grasp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17769">
        <property type="entry name" value="PurK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="SSF51246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01161">
        <property type="entry name" value="purK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00065">
        <property type="entry name" value="D_2_HYDROXYACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 5 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 4 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1 3 5" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="6">
        <location>
            <begin position="113"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="149"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="154"/>
            <end position="160"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="184"/>
            <end position="187"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="215"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="269"/>
            <end position="270"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV57411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="380" mass="41139" checksum="2FE73AE3609416B2" modified="2019-10-16" version="1">MNPTAIVPPGSTIGVFGSGQLGRMFTMVAKQMGYRVVIYSPDADSPAGQVADREIVAQYDDQSAVEDFARQCDVITLEFENIPVETVGWAGAITPVHPDARVLHVAQDRIIEKQTLADAGLPVTPFRPVFNADDVRRAADELGYPIVLKTARSGYDGKGQRILRDPESIEAALAELGSDRLVAEKMIDFQREVSILVYRSRNGSVGTYPLIENHHANHILDYSICPAAGSDTLRDAARQIALTTAKSLDLVGLLCIELFVQSDDRLLINELAPRPHNSGHLTIEAFPCCQYQQLLRAICGLPLGTEPQTRPAAMANLLGDVWDGGAPAFENALAVEAVQLHLYGKQDAVPGRKMGHLTATADSIEAALANVLAARDQLKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWG7</accession>
    <name>A0A518IWG7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lipase (Class 3)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_34360</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002921">
        <property type="entry name" value="Fungal_lipase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01764">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lipase_3" evidence="2">
        <location>
            <begin position="81"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="276"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="302" mass="34794" checksum="94BED55DE8FD6C85" modified="2019-10-16" version="1">MPKVIHDQGEKPLIVHSELRGPIRELSFLRRSLLFAELSMISYNDEREAREAAEAIGFTTVKFFNNDGSQAYQFANDYDCVIASRGTEPNEWNDIQADANAATVLAETAGRVHRGFKKEVDDLWPMLEVVLKKNDRPLWFCGHSLGGAMATICAGRCFLSYIASNPEELYTFGSPRVGDRRYVNYVKLTHYRWVNNNDIVTRVPPTWLGYRHRGNEIYLDYQGRIRKLEGWWRTQDRLHGFLRGLRKFNIDHFSDHLIHMYIEAILRATYEEEGISEPPEPVKLAPPAPHLPESQPSRSTTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWJ4</accession>
    <name>A0A518IWJ4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pyridoxal 4-dehydrogenase</fullName>
            <ecNumber evidence="2">1.1.1.107</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">pld1</name>
        <name evidence="2" type="ORF">Mal33_34560</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.1.107" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050235">
        <property type="term" value="F:pyridoxal 4-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42686">
        <property type="entry name" value="PTHR42686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="1">
        <location>
            <begin position="16"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="346" mass="38068" checksum="7DFD3F7587CFC65E" modified="2019-10-16" version="1">MQRQLFGKTGLRIPPVVFGSTSLGNLFAEVPDEAKQQVVAEWFRRVEAPVFIDSAGKYGAGMSLEIIGRELARLNIDPADVVISNKLAWTRQPLVGDEPTFEPGAWFGLTHDARQEISYEGILRCYHQGNELLGDYQAGLVSVHDPDEYLAAATDSADHKQRWHDIEEAYRALGELRSEGKVLGVGVGAKEWTSIRDVCDRVDLDWVMLANSLTIMKHPPELLAFIEQLDEAGVGILNAAVFNAGFALGGKFYDYRVVTGESAEDRELLDWRQRFQTACQRFDVAPAAACLEFARSVPGIQAVAISSSSPHNIARTVAAVDGAAPPSFWSHLKEMHVIDPSFPFLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXA4</accession>
    <name>A0A518IXA4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Dipeptide transport system permease protein DppB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">dppB</name>
        <name evidence="7" type="ORF">Mal33_37290</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045621">
        <property type="entry name" value="BPD_transp_1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19300">
        <property type="entry name" value="BPD_transp_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="99"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="136"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="172"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="280"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="97"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV57716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="308" mass="33386" checksum="8B56D1440F9B42C7" modified="2019-10-16" version="1">MQDLITFLIRRLGWMLLTLWIVFTVSFFLMRFVPGGPFSSEKNVPEAIKRNIEARYGLNDPLPTQYFRELGRDLTGDFGPSFRLEDFSVNEVIAQGFPISASLAILALSFALLLGVTAGVVSALKPGSLGDLTLMILATLGIAIPNFVLASILIIVFVFGLNLFPTAGWGSAWHLVLPALCLGAPVAAYIARLTRAGLLETIGQDYIRTAKAKGLPMYKVIGKHALRGALLPVVSYLGPAAARVLTGSIVLEQIFAIPGMGSHFVEAALQRDYSLAMGLVLVYTALLFLMNTLVDLSYSIIDPRVKLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXG8</accession>
    <name>A0A518IXG8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">tRNA uridine(34) hydroxylase</fullName>
            <ecNumber evidence="2">1.14.-.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">tRNA hydroxylation protein O</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rluA_1</name>
        <name evidence="2" type="synonym">trhO</name>
        <name evidence="5" type="ORF">Mal33_37890</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>AH2 + O2 + uridine(34) in tRNA = 5-hydroxyuridine(34) in tRNA + A + H2O</text>
            <dbReference type="Rhea" id="RHEA:64224"/>
            <dbReference type="Rhea" id="RHEA-COMP:11727"/>
            <dbReference type="Rhea" id="RHEA-COMP:13381"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:136877"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TrhO family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the pseudouridine synthase RluA family.</text>
    </comment>
    <dbReference type="EC" id="1.14.-.-" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140098">
        <property type="term" value="F:catalytic activity, acting on RNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001522">
        <property type="term" value="P:pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00469">
        <property type="entry name" value="TrhO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006225">
        <property type="entry name" value="PsdUridine_synth_RluC/D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006224">
        <property type="entry name" value="PsdUridine_synth_RluC/D_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020936">
        <property type="entry name" value="TrhO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040503">
        <property type="entry name" value="TRHO_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43268">
        <property type="entry name" value="PTHR43268"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17773">
        <property type="entry name" value="UPF0176_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00005">
        <property type="entry name" value="rluA_subfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01129">
        <property type="entry name" value="PSI_RLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Rhodanese" evidence="4">
        <location>
            <begin position="131"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR606225-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV57775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="600" mass="66051" checksum="6EA012B790C2B38C" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXK4</accession>
    <name>A0A518IXK4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative ABC transporter ATP-binding protein YxlF</fullName>
            <ecNumber evidence="5">3.6.3.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">yxlF_2</name>
        <name evidence="5" type="ORF">Mal33_38300</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.6.3.-" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="7"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="46"/>
            <end position="53"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV57815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="322" mass="35155" checksum="4B9EC6BEF04AE70E" modified="2019-10-16" version="1">MQSHHAIDIQDLRKTYRSGIFRRRGQQALRGVSLNVRPGEVFGLLGPNGAGKTTLIKILLGIVHKSAGSATMLGHAAGSQASRSRVGYLPESLRVAKHHTARTALNFYGRLSRMSSQQIARRSDELLDLVGLRQRDRESVRGFSKGMGQRLGLAQALLHDPDLLILDEPTDGLDPLGRSQVRDIINELKGQGKTIFLNSHILQEVEMICDRFAIMAQGELKAIGSIDDLRGTNGRSSATLIVSRLSSETVAALNQGEAAVRTEAIDPDLQRLLVDECPQSELDRIVDLLRGAGASIHQIQRGSSTLEQIFLSLVQPQPLESL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXP8</accession>
    <name>A0A518IXP8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ATP-dependent protease ATPase subunit ClpY</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">clpY</name>
        <name evidence="8" type="ORF">Mal33_38730</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ClpX chaperone family. HslU subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009376">
        <property type="term" value="C:HslUV protease complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004491">
        <property type="entry name" value="HslU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48102:SF3">
        <property type="entry name" value="PTHR48102:SF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00390">
        <property type="entry name" value="hslU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="6">
        <location>
            <begin position="59"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="domain" description="ClpB_D2-small" evidence="7">
        <location>
            <begin position="355"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="153"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV57858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="463" mass="52328" checksum="1677B5C9C135ABD2" modified="2019-10-16" version="1">MSDSHNVVDALGKLTPAETVKQLDRYIVGQRQAKRAVAVALRNRWRRQQLSEEMQGEIAPKNILMIGPTGVGKTEIARRLARMTGAPFIKVEATKYTEVGYYGRDVESMVRELVENGLGLVREKFQDQVREEAEQRVENRLVDLLVPGSTELPSLSQALEESATETADDAEQRLQRTRDKMRKMLQAGKLEERLVEVTTQSKSAPMVVGGMGMENMDIDLQGMFEKIMPRGSQSREMKVNEARQVLMEQETEALLDPEAMNAEAIRLAEELGIIFVDEIDKVIATDGKNADVSRQGVQRDLLPIVEGTSVQTRYGYVRTDHILFIAAGAFHRGKPSELMPELQGRFPIRVELDELTEHDFLQILTEPKNSLTRQYEALLATEQVTIEFQQDALAQLARYAFKVNQSTQNIGARRLYTIMERLLEELSFEAPELGKSSVKIDAAYVEQRLNEIAEDEDLSKFIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXS1</accession>
    <name>A0A518IXS1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nitrite reductase (cytochrome; ammonia-forming)</fullName>
            <ecNumber evidence="2">1.7.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">nrfA</name>
        <name evidence="10" type="ORF">Mal33_39000</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>6 Fe(III)-[cytochrome c] + 2 H2O + NH4(+) = 6 Fe(II)-[cytochrome c] + 8 H(+) + nitrite</text>
            <dbReference type="Rhea" id="RHEA:13089"/>
            <dbReference type="Rhea" id="RHEA-COMP:10350"/>
            <dbReference type="Rhea" id="RHEA-COMP:14399"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16301"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="EC" id="1.7.2.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome c-552 family.</text>
    </comment>
    <dbReference type="EC" id="1.7.2.2" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042279">
        <property type="term" value="F:nitrite reductase (cytochrome, ammonia-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00548">
        <property type="entry name" value="NrfA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003321">
        <property type="entry name" value="Cyt_c552"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036280">
        <property type="entry name" value="Multihaem_cyt_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30633">
        <property type="entry name" value="PTHR30633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02335">
        <property type="entry name" value="Cytochrom_C552"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000243">
        <property type="entry name" value="Cyt_c552"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48695">
        <property type="entry name" value="SSF48695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0106">Calcium</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00029373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV57885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="523" mass="58392" checksum="C9DCD87FA14EE80D" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IY23</accession>
    <name>A0A518IY23_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 9">tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase</fullName>
            <ecNumber evidence="8 9">2.8.4.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">(Dimethylallyl)adenosine tRNA methylthiotransferase MiaB</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">tRNA-i(6)A37 methylthiotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9 13" type="primary">miaB</name>
        <name evidence="13" type="ORF">Mal33_39990</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 9">Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>[sulfur carrier]-SH + AH2 + N(6)-dimethylallyladenosine(37) in tRNA + 2 S-adenosyl-L-methionine = 2-methylsulfanyl-N(6)-dimethylallyladenosine(37) in tRNA + 5'-deoxyadenosine + [sulfur carrier]-H + A + 2 H(+) + L-methionine + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:37067"/>
            <dbReference type="Rhea" id="RHEA-COMP:10375"/>
            <dbReference type="Rhea" id="RHEA-COMP:10376"/>
            <dbReference type="Rhea" id="RHEA-COMP:14737"/>
            <dbReference type="Rhea" id="RHEA-COMP:14739"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:29917"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:64428"/>
            <dbReference type="ChEBI" id="CHEBI:74415"/>
            <dbReference type="ChEBI" id="CHEBI:74417"/>
            <dbReference type="EC" id="2.8.4.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="9">Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the methylthiotransferase family. MiaB subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.8.4.3" evidence="8 9"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035596">
        <property type="term" value="F:methylthiotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.30.20">
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
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        <property type="entry name" value="Methylthiotransferase"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="rSAM_horseshoe"/>
    </dbReference>
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        <property type="entry name" value="TRAM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00919">
        <property type="entry name" value="UPF0004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00273">
        <property type="entry name" value="(dimethylallyl)adenosine_tRNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00089">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51449">
        <property type="entry name" value="MTTASE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01278">
        <property type="entry name" value="MTTASE_RADICAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50926">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9" id="KW-0408">Iron</keyword>
    <keyword evidence="7 9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 9 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="MTTase N-terminal" evidence="11">
        <location>
            <begin position="3"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="Radical SAM core" evidence="12">
        <location>
            <begin position="155"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="domain" description="TRAM" evidence="10">
        <location>
            <begin position="390"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="12"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
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        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
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        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00033765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="QDV57983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="472" mass="53483" checksum="88624EDB4D95D326" modified="2019-10-16" version="1">MTKRLYIETVGCQMNVLDSEMVVANLRQHGYEVVQSTEDADVLLYNSCSVRQMAEEKIYSAVGEVKRIKEAHPDRVVGIMGCMAQKDQAKIFDRAPHVDLVIGPGQLHQIPDLIQQVRAGAGPQVMVSLGRKEGSQADIRRSHETFDPLRDPSMRPTPFQAYLRIQIGCDKFCTYCVVPMTRGPEQGRRPADILLEAQTLADQGCKEITLLGQTVNSYKYSEDGTTTRLADLLRSLHEIDGIERLKFVTNYPKDMTEDLLRTVHELPKCSPYLHVPAQSGSDEVLKRMKRGYTIADYRAMMERIHKFLPEASVSSDFIVGFCGETEEQFQMTMDLVREYRYKNSFIFQYSVREGTVANQRLEDDIPLDVKKRRNNDLLNLQNEICLEDNQRFVGETVQVLVEGPSKKAIKNGDDGPVVQMTGRTHCDRIVVFDGNRRQAGQMMDIVVREALCHTLIGTVHTKHLGPQVFQLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IY53</accession>
    <name>A0A518IY53_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Plasmid stabilization system protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_40270</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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        <property type="entry name" value="RelE/ParE_toxin"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF143011"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1277">Toxin-antitoxin system</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="95" mass="10668" checksum="2C4BABA0504DC176" modified="2019-10-16" version="1">MAQVIFSPEADDDLVAIVDYIARDKPMAARQWLAEILKTCEMLANQPGVGEDRNGFGVMGCRSYRVGQYVVFFRAREDGIEVSRVIHGSRDMTNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYA0</accession>
    <name>A0A518IYA0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_40770</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ARM-like"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="425" mass="46176" checksum="442B19BB99E4186A" modified="2019-10-16" version="1">MNHDQSSNPFAYRRQRRFAGWPWWAAIGVVIVLTVFVVPRVCNWFLLNQLTQGIEDLPLGTQTERLQAIGHLGVPGIPVLVKSLGHRDRGVARSSLQVLKSMQDQMMQKGDAEGAACHFELTRQLADQLPQIPQDRHPWVGELLNQTLLDTLDIDLQRAKTSYRTATSLLSQLVLPVDAAANAPLLATAAPALPIAVSRQATPQSLPTNLTNEAEFLPNLQPLAVAPATQSPASQNVLDENLWVDPTRRPPPTPAAELVETSSLEPEMLPSGPAATEAPVTLPIGGSAPILSAGGYSTDGALEAYSTRAVIDLLSSIRKPLASAARSELIQRGFQPVDLSLAIRLASTNADVRNSLIDDITNRSDIDPRRWLLWLAEDAERSVRLRALAALGTMRDPNVAKELRSLLSTEQDPAVAARIRQALVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYA6</accession>
    <name>A0A518IYA6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">D-threonine aldolase</fullName>
            <ecNumber evidence="3">4.1.2.42</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_40710</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DSD1 family.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.42" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043876">
        <property type="term" value="F:D-threonine aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.37.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001608">
        <property type="entry name" value="Ala_racemase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026956">
        <property type="entry name" value="D-ser_dehydrat-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042208">
        <property type="entry name" value="D-ser_dehydrat-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01168">
        <property type="entry name" value="Ala_racemase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14031">
        <property type="entry name" value="D-ser_dehydrat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01119">
        <property type="entry name" value="D-ser_dehydrat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="SSF51419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="D-ser_dehydrat" evidence="2">
        <location>
            <begin position="257"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="363" mass="39258" checksum="02170B0CF2005708" modified="2019-10-16" version="1">MNWKNIEGLDGVESPGLLVDSDKIQQNIDRMIEIVGGAEHVDRLFPHVKTHKMPEVTRMQVDAGITKFKAATLSEAQMAAGAGASEVLIAHQLVGPKLDRLATLIEDFPNTKFAVLTDDPQAADAINEKCGDADSPLDVYIDIDCGMHRTGIPLGARSDALRAHIDSLSGLNFAGLHVYDGHLHDPDLQQRTDKVKEILGKVALHEKEHPSPRIIVGGSPTFGIWAAETSWHLSPGTTLLWDFGYGDAHPDLPMTIAAALISRVISKPGEGKICIDLGHKSIAAEMPLEKRFQFPDLPDAQPIGQSEEHLVLQTANAASLHVGDIVIAIPRHICPTVALHSHATVVSGGRVTGDRWQVTARDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ80</accession>
    <name>A0A518IZ80_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Foldase protein PrsA 2</fullName>
            <ecNumber evidence="5">5.2.1.8</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">prsA2</name>
        <name evidence="5" type="ORF">Mal33_44160</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="5.2.1.8" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000297">
        <property type="entry name" value="PPIase_PpiC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027304">
        <property type="entry name" value="Trigger_fact/SurA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00639">
        <property type="entry name" value="Rotamase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109998">
        <property type="entry name" value="SSF109998"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50198">
        <property type="entry name" value="PPIC_PPIASE_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0697">Rotamase</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021909555" evidence="3">
        <location>
            <begin position="24"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="domain" description="PpiC" evidence="4">
        <location>
            <begin position="168"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="domain" description="PpiC" evidence="4">
        <location>
            <begin position="447"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="353"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV58398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="605" mass="67438" checksum="0E3F7F37406A241B" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZA2</accession>
    <name>A0A518IZA2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_44310</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="45" mass="4832" checksum="605453BFF36FC753" modified="2019-10-16" version="1">MGPIKLPLGPSEEFLDEFNRLYGGIQLRIEEAAATPTTAPTTGDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZE0</accession>
    <name>A0A518IZE0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Co-chaperonin GroES</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">10 kDa chaperonin</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Chaperonin-10</fullName>
            <shortName evidence="3">Cpn10</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">groS_1</name>
        <name evidence="3" type="synonym">groES</name>
        <name evidence="3" type="synonym">groS</name>
        <name evidence="5" type="ORF">Mal33_44860</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 4">Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3 4">Belongs to the GroES chaperonin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00320">
        <property type="entry name" value="cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.33.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00580">
        <property type="entry name" value="CH10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020818">
        <property type="entry name" value="Chaperonin_GroES"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037124">
        <property type="entry name" value="Chaperonin_GroES_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018369">
        <property type="entry name" value="Chaprnonin_Cpn10_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10772">
        <property type="entry name" value="PTHR10772"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00166">
        <property type="entry name" value="Cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00297">
        <property type="entry name" value="CHAPERONIN10"/>
    </dbReference>
    <dbReference type="SMART" id="SM00883">
        <property type="entry name" value="Cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00681">
        <property type="entry name" value="CHAPERONINS_CPN10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00580"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV58463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="98" mass="10298" checksum="4798B736BBF5A17D" modified="2019-10-16" version="1">MAKINIRPLDDRIVVQPASAEETTAGGIVLPDSAQEKPQRGTVVAVGPGKLLDSGSRGELTVAIGDVVIYGRYGGSEIEVDGQELKILRESDILAKVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZU0</accession>
    <name>A0A518IZU0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Prolyl tripeptidyl peptidase</fullName>
            <ecNumber evidence="4">3.4.14.12</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ptpA_2</name>
        <name evidence="4" type="ORF">Mal33_46340</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.4.14.12" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002469">
        <property type="entry name" value="Peptidase_S9B_N"/>
    </dbReference>
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        <property type="entry name" value="VHL_beta_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="VHL_sf"/>
    </dbReference>
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        <property type="entry name" value="DPPIV_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF49468"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021987046" evidence="1">
        <location>
            <begin position="29"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="domain" description="DPPIV_N" evidence="3">
        <location>
            <begin position="292"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S9" evidence="2">
        <location>
            <begin position="628"/>
            <end position="817"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV58610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="822" mass="93552" checksum="2B2D278FE1242652" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZZ9</accession>
    <name>A0A518IZZ9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">5-dehydro-4-deoxyglucarate dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_46970</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="1 2">Mal33</strain>
        </source>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002220">
        <property type="entry name" value="DapA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12128">
        <property type="entry name" value="PTHR12128"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00701">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01130">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="304" mass="33076" checksum="C95429136A3AA02B" modified="2019-10-16" version="1">MQTTPVTYENLRDSIIAVPPLCRDADYRICKTENEKLVRHIEAGGVSSLLYGGNANLYHVRVSEYAQMLEMLSEIAGDKTLVIPSVGPAYGLMMDQADLLRDTKFPTVMVLPADAVMTESGLLRGFRHFVEAIGRPAVLYIKREGYITPEGAAKLVDDGLVSFIKYAIVRDDPAVDPFLDQLVDCVDRKLIVSGIGEQPAIVHLKQFGITGFTSGCVCVAPGLSQQMLQALYADDVEKAESIRKTFLPLEDLRNGINPIRVLHQAVASAGIAATGPQIPLLDEIDPSRVEEIRVAATELLAAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J055</accession>
    <name>A0A518J055_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_47360</name>
    </gene>
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        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
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            <taxon>Planctomycetes</taxon>
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            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="72" mass="7815" checksum="EB684FA3F793D51C" modified="2019-10-16" version="1">MTNATDALPDKIVVESLNGQNETIVDGETMQFELPEHAADAWAAVLIDVYDKRKQDSPNETPAIGNGDVTSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J087</accession>
    <name>A0A518J087_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Probable membrane transporter protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Mal33_47810</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002781">
        <property type="entry name" value="TM_pro_TauE-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01925">
        <property type="entry name" value="TauE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="43"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="71"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="95"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="157"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="191"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="223"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="256"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV58756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="274" mass="28013" checksum="DBE3C2E12A02A28B" modified="2019-10-16" version="1">MLGLAVLFGVVVGFALGLTGGGGGVFAVPLLVYGLSFSPREAVGISLAAVGGTALFGAIPRLVRGEVELRTGLLFAVAGMLGAPIGSYLSTLVPANVLLVMFALLMFVVAQRMWSKACNPTLPSGVCTTEDEPGPDRSACQRDADGKLRLTSRCARLLVAVGLMTGVLSGMFGVGGGFVIVPALVIFSGMAIHQAVGTSLFVIVLVSISGVASHIVGGNELSLTTTLQFMAGGFVGMWIGGIVAKRLKGPTLQKTFSIAVVLVAVFVIFKSVVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0B0</accession>
    <name>A0A518J0B0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PhoPQ-activated pathogenicity-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_48080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
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                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="QDV58783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="PTHR31497"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021769349" evidence="1">
        <location>
            <begin position="18"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="458" mass="51106" checksum="A75A7BD02D53FA59" modified="2019-10-16" version="1" precursor="true">MKWICSLFLLFPLLSQAVCCGQDVATEMSLAKMVMQRDDAYGWEICDRGQISDCEYLQLHLTSQRWQGVTWQHTLIVILPPQVDPQHNNALMLIDGGRWKESWNENGPGALPLPETAKLMAVMARDLKTPVAIIRQVPFQPMMGGLHEDALIAMTLKKYYETEDRSWPLLPAMARAASRALDAVTEVAQQEWKLQLDSFTVTGASKRGWTTYLLGATDPRVKAIAPMVIDMLNMEPQMKHQLASWGAYSPQIEDYTKLGLQKSIGTPAGNELMQLIDPYTQREKLKMPKLVILGTNDPYWPVDAQQFYFEDLPKPRTLLNIPNNGHGLKDISRMIGSISALHRSMITKTPLPILQSECIDQAGNTAIVASSDKSPSRVYGWIARSKSRDFRDARWHAKALSADADGTWRLPLAKPEEGYVVGMIEAQYDGPTTFPLSITTMVKVVPGLPADVEEAAGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0J4</accession>
    <name>A0A518J0J4_9BACT</name>
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        <submittedName>
            <fullName evidence="3">Inner membrane protein YqiK</fullName>
        </submittedName>
    </protein>
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        <name evidence="3" type="primary">yqiK</name>
        <name evidence="3" type="ORF">Mal33_48850</name>
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        <name type="scientific">Rosistilla oblonga</name>
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            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
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    </dbReference>
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        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
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        <property type="entry name" value="Flotillin_fam"/>
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    <dbReference type="PANTHER" id="PTHR13806">
        <property type="entry name" value="PTHR13806"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF117892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="14"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="238"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="358"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="713" mass="79006" checksum="1CC43607B96E54FC" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0M1</accession>
    <name>A0A518J0M1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Mal33_49160</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="14"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="40"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="77"/>
            <end position="96"/>
        </location>
    </feature>
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        <location>
            <begin position="102"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
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            <end position="156"/>
        </location>
    </feature>
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        <location>
            <begin position="176"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
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            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
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            <end position="279"/>
        </location>
    </feature>
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            <end position="309"/>
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    </feature>
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            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="353"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="379"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="1"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV58891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="411" mass="44262" checksum="3C6BF50218C3D795" modified="2019-10-16" version="1">MTAVDTPRLYDRNFMLALASQMCFVIANTLMAHYSRWIEFLGGGLGQVGLIMGASATLGLLLRPWIAQWINRLGARLMWLIGYLLFAASAFSNLLLDDLNPLIYLIRALQLLAAAIVFASGLTYISQTAPEHRRTEAIGVLGAGGFFGMLIGPYLGDLILGSGADAAMVARQRSDFVWLFISASLASLLPTIFLILMRTPGSVGTRRSVKLSDFVSTTIRYWPGSVLLIDFIFGICMTAPFIFVASFIDSEPLVIGKHSVIGIFFICYAGWGVTVRLALGNLPDRVGPHKILVIGTALMAIGMFSYAIVSAQHPWLIVIPALLTGTGHGLMFHTMTSLTIQPFPMEVRGTGSALAMMMLDLGTLVGAPALGYVGDRFGYASMFATVGSICVVGMGIYVWRDAAVRLANPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0N7</accession>
    <name>A0A518J0N7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">UDP-glucose 6-dehydrogenase</fullName>
            <ecNumber evidence="3">1.1.1.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">tuaD</name>
        <name evidence="11" type="ORF">Mal33_48900</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mal33</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Nucleotide-sugar biosynthesis; UDP-alpha-D-glucuronate biosynthesis; UDP-alpha-D-glucuronate from UDP-alpha-D-glucose: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.22" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00038">
        <property type="reaction ID" value="UER00491"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003979">
        <property type="term" value="F:UDP-glucose 6-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006065">
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</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
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    <name>A0A518J0R3_9BACT</name>
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            <authorList>
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</entry>
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    </evidence>
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        <source>
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    </evidence>
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</entry>
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    <name>A0A518J0U7_9BACT</name>
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Boedeker C."/>
                <person name="Pinto D."/>
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                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
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</entry>
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                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
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                <person name="Lage O.M."/>
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                <person name="Devos D.P."/>
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                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <source>
            <dbReference type="EMBL" id="QDV59029.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
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</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="1 2">Mal33</strain>
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            <dbReference type="EMBL" id="QDV59039.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
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    <name>A0A518J1D5_9BACT</name>
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="78"/>
            <end position="100"/>
        </location>
    </feature>
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        <location>
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        </location>
    </feature>
    <feature type="domain" description="HlyD_D23" evidence="3">
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        </location>
    </feature>
    <feature type="domain" description="HMBD" evidence="4">
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            <begin position="431"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
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        </location>
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    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="74"/>
        </location>
    </feature>
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    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF19335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV59142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="724" mass="77648" checksum="E5F62CDEF5D4B7E6" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1L1</accession>
    <name>A0A518J1L1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Indole-3-glycerol phosphate synthase</fullName>
            <shortName evidence="8">IGPS</shortName>
            <ecNumber evidence="8">4.1.1.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8 10" type="primary">trpC</name>
        <name evidence="10" type="ORF">Mal33_52480</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate + H(+) = (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:23476"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:58613"/>
            <dbReference type="ChEBI" id="CHEBI:58866"/>
            <dbReference type="EC" id="4.1.1.48"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 4/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the TrpC family.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.48" evidence="8"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00043"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004425">
        <property type="term" value="F:indole-3-glycerol-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000162">
        <property type="term" value="P:tryptophan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00331">
        <property type="entry name" value="IGPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00134_B">
        <property type="entry name" value="IGPS_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045186">
        <property type="entry name" value="Indole-3-glycerol_P_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013798">
        <property type="entry name" value="Indole-3-glycerol_P_synth_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001468">
        <property type="entry name" value="Indole-3-GlycerolPSynthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22854">
        <property type="entry name" value="PTHR22854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00218">
        <property type="entry name" value="IGPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00614">
        <property type="entry name" value="IGPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 8" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="4 8" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="7 8 10" id="KW-0456">Lyase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="domain" description="IGPS" evidence="9">
        <location>
            <begin position="5"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV59220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="261" mass="28204" checksum="FA1D09D482792663" modified="2019-10-16" version="1">MSTILDTIIAKKHQEVAAAKLVQPIEKLEALAAAAPPTLDFIAALAATPDVRLIAEVKKASPSAGIIREDFDPVAIATAYAQSGAACISVLTDETFFQGSLDFLRQIRAAVEIPLLRKDFIIDRYQLLEARAAGADCVLLIAECLSSEELITLHRQAAELGLQTLIEFYDDENLPAVLATDGRLVGVNNRDLRTFHTDLQHTVRMRSQIPTDRLLVGESGIRTYEDVKMLGAAGVKAILVGESLMRQADIGEAVRSLLGTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1R8</accession>
    <name>A0A518J1R8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transglutaminase-like superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_53080</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002931">
        <property type="entry name" value="Transglutaminase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01841">
        <property type="entry name" value="Transglut_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00460">
        <property type="entry name" value="TGc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="34"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="68"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="93"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="119"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="141"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="178"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="TGc" evidence="3">
        <location>
            <begin position="521"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="274"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV59280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="744" mass="82271" checksum="1680BCE2E4603063" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J277</accession>
    <name>A0A518J277_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Toxin RTX-I translocation ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">apxIB</name>
        <name evidence="10" type="ORF">Mal33_54730</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="181"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="214"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="295"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="325"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="405"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="434"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="182"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="496"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="529"/>
            <end position="536"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV59438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="717" mass="78530" checksum="DD7A1D28471D705D" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J2C4</accession>
    <name>A0A518J2C4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 12">Phosphoribosylformylglycinamidine cyclo-ligase</fullName>
            <ecNumber evidence="3 12">6.3.3.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 12">AIR synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11 12">AIRS</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9 12">Phosphoribosyl-aminoimidazole synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12 15" type="primary">purM</name>
        <name evidence="15" type="ORF">Mal33_55180</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8 12">
            <text>2-formamido-N(1)-(5-O-phospho-beta-D-ribosyl)acetamidine + ATP = 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole + ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:23032"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:137981"/>
            <dbReference type="ChEBI" id="CHEBI:147287"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.3.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 12">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole from N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide: step 2/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the AIR synthase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.3.1" evidence="3 12"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00129"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004641">
        <property type="term" value="F:phosphoribosylformylglycinamidine cyclo-ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02196">
        <property type="entry name" value="PurM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.650.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00741">
        <property type="entry name" value="AIRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010918">
        <property type="entry name" value="PurM-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036676">
        <property type="entry name" value="PurM-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016188">
        <property type="entry name" value="PurM-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036921">
        <property type="entry name" value="PurM-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004733">
        <property type="entry name" value="PurM_cligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10520">
        <property type="entry name" value="PTHR10520"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00586">
        <property type="entry name" value="AIRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02769">
        <property type="entry name" value="AIRS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55326">
        <property type="entry name" value="SSF55326"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56042">
        <property type="entry name" value="SSF56042"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00878">
        <property type="entry name" value="purM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 12 15" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AIRS" evidence="13">
        <location>
            <begin position="62"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="AIRS_C" evidence="14">
        <location>
            <begin position="180"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00033093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="QDV59483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="352" mass="37780" checksum="B0FD8554B0CBF4CC" modified="2019-10-16" version="1">MPVTYKDSGVDLDLYAQAMQRLPSLARRTFSPRVVSNDGGFAGLFKLDFSSPLFSRNYEDPILVAGTDGVGTKLKVAQMTGRHDTVGIDLVAMCVNDLICTGAEPLFFLDYIAMGRDDADRLEQVVKGISDGCLQADSALLGGETAIMPDMYAAEDYDLAGFAVGVVDRKHLVDGKSIVPGDKIIGISSDGIHSNGYSLVRKIISHAGIALDACPAELGGASVADELLRPTRIYSSMLRRVLGHYRVKHVVHGIAHITGGGLHENLSRILPKTVDTVIQPDSWPMPPVFPWLQGLGDVADDEMQRVFNMGLGLVLVVSDFYAAKIMELVRAGGCECTEIGHVEAGSGESRFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J2E2</accession>
    <name>A0A518J2E2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acetylxylan esterase</fullName>
            <ecNumber evidence="4">3.1.1.72</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">axeA1_4</name>
        <name evidence="4" type="ORF">Mal33_55410</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.1.72" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046555">
        <property type="term" value="F:acetylxylan esterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021912877" evidence="1">
        <location>
            <begin position="24"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="domain" description="Abhydrolase_3" evidence="3">
        <location>
            <begin position="69"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S9" evidence="2">
        <location>
            <begin position="210"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV59506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="302" mass="32362" checksum="B26C230F9F8DB9FF" modified="2019-10-16" version="1" precursor="true">MMKLKAFLFAPLTCLILSATVVADSPEPKPLWKDGAPGAGGDQVGDLPNLTIYKAAGDGPRPAIVVLPGGGYGGLAIDHEGYAIANWLQDLGVTAAICQYRHRGKGNQGAGYKHPYPLMDAQRAIRTLRAQAAELNIDPNRIGILGFSAGGHLASTAATHFDDGNPDASDPIDRVSCRPDFAVLCYAVIGLNKPYTHRGSQRNLLGEDAPEELVESLSNESQVTEKTPPTFLFHTSGDTGVPPQNSVHFYLACHEHKVPVEMHIFEKGRHGLGLAAGRPGAEHWPMLCHEWMISRGILPAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMA2</accession>
    <name>A0A518IMA2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Pheromone autoinducer 2 transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Mal33_01520</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.</text>
    </comment>
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        <property type="protein sequence ID" value="QDV54203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002549">
        <property type="entry name" value="AI-2E-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21716">
        <property type="entry name" value="PTHR21716"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01594">
        <property type="entry name" value="AI-2E_transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="32"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="62"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="145"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="200"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="227"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="262"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="302"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV54203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="347" mass="37763" checksum="1256351E1CFED825" modified="2019-10-16" version="1">MPNAKTTLFALLLLALVLATAGLLVPTLNVCLLIMAGLLFGVFVHAISVWSANKFSLAYRTTYLMVVGLMLLAIGLGIFQLGSQVADRADELWNQLQSAAQTANEQLEQHAWAQKHLPDVSDIEEQLTQSSSDILPAVLQRLQSLGWGMTAAMVIFFVGLYVAYDPDLYRDGLVKLMPPAKRERTQKVLDRMNGSLQRWIVARFVSMAIVGIATAIGMWTFGIAMPITLGVLAALLTFIPNIGPLLAAIPQMLLAVNVGPQMVLYVLMFNVVLQTFESYLITPIVQQREVSLPPVLTIAAQLLMGVVVGILGVMMAAPMVVVAMVLVQTLYIDDRPQDDDSPSSAEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMB7</accession>
    <name>A0A518IMB7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CRISPR-associated protein, family (Cas_GSU0054)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_01920</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
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        </lineage>
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    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
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                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019089">
        <property type="entry name" value="Cas_GSU0054"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09609">
        <property type="entry name" value="Cas_GSU0054"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02165">
        <property type="entry name" value="cas5_6_GSU0054"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="482"/>
            <end position="513"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="554" mass="60698" checksum="90E7C4BCE3B6BEF2" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMD2</accession>
    <name>A0A518IMD2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Helix-turn-helix protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_01960</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="48"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="110" mass="11673" checksum="5684BFCD961BC09D" modified="2019-10-16" version="1">MTDDERAAFEQAVAEEQAAKAENVAASGDAAMRLRAEAAIAMQLIALLKTEREAAGVSLSEMETRTGMQKSALSRLENSAAPNPMLSTLQRYAAAIGKRLDFAIESGCDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMI7</accession>
    <name>A0A518IMI7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_02580</name>
    </gene>
    <organism evidence="1 2">
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        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018644">
        <property type="entry name" value="DUF2071"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39186">
        <property type="entry name" value="PTHR39186"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09844">
        <property type="entry name" value="DUF2071"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="228" mass="26397" checksum="DB8174583CD8A108" modified="2019-10-16" version="1">MKFLSAHWKHLLLANYNVQASVLEPFVPRGTQIDAFEGQVYVSLVAFMFEETRLVGIPIPFHRRFEEVNLRFYVSPKNNPSIRAVTFIKELVPKRIIPLIANNLFHENYAALPMDHCNEPNRHWYSWQNASHNRFSANIDSELALPTADSLGEFITEHYWGYSQGPRRTLQYEVRHPQWRCCQIDDFEIDVDFAATYGEAFAFLNTQPPTNVQYAEGSPVTVSFPSQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMK9</accession>
    <name>A0A518IMK9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HEPN_Apea domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_02670</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041229">
        <property type="entry name" value="HEPN_Apea"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18739">
        <property type="entry name" value="HEPN_Apea"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HEPN_Apea" evidence="1">
        <location>
            <begin position="259"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="416" mass="45871" checksum="63DA455904EABD4F" modified="2019-10-16" version="1">MGETEHLDQFFSKLMSDKVMGKIVGDINSERQRQIDGGWLGDKPFAEADYPQRIDFDLYRTFAGGQLTRSFNEHLLSQFTFPPLTAGELGELACDHFAGAYHAEELSAALFRLSAHVGRLTTYTADDFNICFDVAKVSGAAFDIPHEMRDCPRLFESPHGFWISFSESGNPFSPATIDLSGKFSELALKEVSVSVARIATSASRTVHLVNCDPKLPDVYGYVPFEVSQSAVWDDFKRLGKSFFSHLISSYFLAPVGKASTLDQRLRNAAHLLAEADSQDSAAISLSLSFSAIEAIVCSKTDGIVDELSRNVASLLEPDKLNRIDAIAAIKSLYNLRSKTLHGASVNGDDKARWKARTLAAAIVRAVYEWQEHIARMGECASRDGFLCELKSLSVTGSQMVGVSERLSRFIPTNDNW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMP6</accession>
    <name>A0A518IMP6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF1080 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_03250</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010496">
        <property type="entry name" value="3-keto-disaccharide_hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06439">
        <property type="entry name" value="DUF1080"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022010440" description="DUF1080 domain-containing protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1080" evidence="2">
        <location>
            <begin position="30"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="262" mass="29232" checksum="DB32B44AB361FDE1" modified="2019-10-16" version="1" precursor="true">MKAPFVVALALVSLFVSSAVTADEAFPKGQWVSLFNGKNLDGWTPKIKGYDLGDNYGNTFRVEDGVIKVGYEAYDSFDKRFGHLFYKQPFSNYRFRVEYRFVGEQCKGGEGWALRNSGVMLHGESPEEMTKDQDFPTSIEVQLLGGDGKRPRTNANLCTPGTNVVKEGKLFTPHCTSSSSKTYHGDQWVTVEIEVRGNDVIRHLIDGEVVLEYTKPQLDERDAHAAKLIEKAGTKVLSGGSISLQSESHPIEFRKVEIMLLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMQ1</accession>
    <name>A0A518IMQ1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_03050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022178168" evidence="1">
        <location>
            <begin position="23"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="332" mass="34648" checksum="34FD525317D11336" modified="2019-10-16" version="1" precursor="true">MKFQLAITLGLFSCLLPGSAFAEDVKVETVLRGLQNPSSVSFSPNGELTVCDSRGLVVMLKEGKPVNYVTGFDTEFWKSDDTGKKWYAVGPLSAIWVGDTLVVSDSGKGDGEETLLMFSAGGKASTGVATNPVGPTSDDAADKGEGNLTGLSATADGKQIFVAGQGFDGKSWVLSADPQTKKMQPLLSADENGIATNSPMQTLVGPDNTLYVLYSGKGGAADGLIVQWDLATKKPVAQWKLDGVINPMGMAHIDGTKFAVVENNWALNNVNEGRVVTVDLGAEGKAEVAETGVKLHGPVACAFGPDNRLYVTQIGEKMDAAEGSVVAISGLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMU5</accession>
    <name>A0A518IMU5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L28</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 5" type="primary">rpmB</name>
        <name evidence="5" type="ORF">Mal33_03640</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the bacterial ribosomal protein bL28 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.170.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00373">
        <property type="entry name" value="Ribosomal_L28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034704">
        <property type="entry name" value="L28p-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026569">
        <property type="entry name" value="Ribo_L28/L24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037147">
        <property type="entry name" value="Ribo_L28/L24_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001383">
        <property type="entry name" value="Ribosomal_L28"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00830">
        <property type="entry name" value="Ribosomal_L28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143800">
        <property type="entry name" value="SSF143800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00009">
        <property type="entry name" value="L28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV54410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="90" mass="10086" checksum="FE483E83A39A9C3E" modified="2019-10-16" version="1">MARQCEVCGKRVQMGNRIETRGKAKYLGGVGTKITGISRRKFVPNLQRVKVSLTTGENKSIRCCTQCIRSGSIRKVVKVKPFELESKTKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMU7</accession>
    <name>A0A518IMU7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C</fullName>
            <shortName evidence="1">Asp/Glu-ADT subunit C</shortName>
            <ecNumber evidence="1">6.3.5.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1 2" type="primary">gatC</name>
        <name evidence="2" type="ORF">Mal33_03650</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O + L-aspartyl-tRNA(Asn) + L-glutamine = ADP + 2 H(+) + L-asparaginyl-tRNA(Asn) + L-glutamate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14513"/>
            <dbReference type="Rhea" id="RHEA-COMP:9674"/>
            <dbReference type="Rhea" id="RHEA-COMP:9677"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:78515"/>
            <dbReference type="ChEBI" id="CHEBI:78516"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O + L-glutamine + L-glutamyl-tRNA(Gln) = ADP + H(+) + L-glutamate + L-glutaminyl-tRNA(Gln) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:17521"/>
            <dbReference type="Rhea" id="RHEA-COMP:9681"/>
            <dbReference type="Rhea" id="RHEA-COMP:9684"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="ChEBI" id="CHEBI:78521"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Heterotrimer of A, B and C subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GatC family.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.-" evidence="1"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050566">
        <property type="term" value="F:asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050567">
        <property type="term" value="F:glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006450">
        <property type="term" value="P:regulation of translational fidelity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00122">
        <property type="entry name" value="GatC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003837">
        <property type="entry name" value="Asp/Glu-ADT_csu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036113">
        <property type="entry name" value="Asp/Glu-ADT_sf_sub_c"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15004">
        <property type="entry name" value="PTHR15004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02686">
        <property type="entry name" value="Glu-tRNAGln"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141000">
        <property type="entry name" value="SSF141000"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00135">
        <property type="entry name" value="gatC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 2" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="95" mass="10511" checksum="AFD1D95625AC8D20" modified="2019-10-16" version="1">MAISLDQVRKLALMARLELSDDELGTITPQLEDIVAFVDKLMELDTDGIEPMVHAVETVNRWVPDQLGDSLSREQALANAPNHDEECFLVPPVLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMZ4</accession>
    <name>A0A518IMZ4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Sensor histidine kinase TmoS</fullName>
            <ecNumber evidence="11">2.7.13.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">tmoS</name>
        <name evidence="11" type="ORF">Mal33_03980</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="11"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902531">
        <property type="term" value="P:regulation of intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="11" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="355"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="8">
        <location>
            <begin position="633"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="10">
        <location>
            <begin position="839"/>
            <end position="892"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="9">
        <location>
            <begin position="893"/>
            <end position="963"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="10">
        <location>
            <begin position="966"/>
            <end position="1018"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="10">
        <location>
            <begin position="1260"/>
            <end position="1312"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="10">
        <location>
            <begin position="1516"/>
            <end position="1568"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="1579"/>
            <end position="1795"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="8">
        <location>
            <begin position="1815"/>
            <end position="1932"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="315"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="5">
        <location>
            <position position="681"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="5">
        <location>
            <position position="1865"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QDV54444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1934" mass="216407" checksum="A0E7BD0C35BB1230" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IN80</accession>
    <name>A0A518IN80_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_05030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="101" mass="10667" checksum="7C0AF4B72D189D10" modified="2019-10-16" version="1">MRFVFVCLLAFTIGCGSEEVVELPAPVEKTQLVATIDQIAATGQVDEGVLTGLTMGLEGAGLMGEAALVQQYPSIGDEARVKKMAKQLSKDVKKKLEAGVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IN85</accession>
    <name>A0A518IN85_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RNA polymerase sigma factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">sigE_1</name>
        <name evidence="9" type="ORF">Mal33_05080</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000838">
        <property type="entry name" value="RNA_pol_sigma70_ECF_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007630">
        <property type="entry name" value="RNA_pol_sigma70_r4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04545">
        <property type="entry name" value="Sigma70_r4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01063">
        <property type="entry name" value="SIGMA70_ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="5 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 6" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="7">
        <location>
            <begin position="14"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4" evidence="8">
        <location>
            <begin position="116"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV54553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="172" mass="19806" checksum="C78405BFBA742FA5" modified="2019-10-16" version="1">MSQRSETDLSPQELITRHQAGVWRYLRLLGCDNSTADDLTQETFLTILRRPPFNQYSDEATAAYLRRIARNLFISLKRRDKRMHLVAAIESLDAVWDRWIGAEEDGEEFISALNECLQGLTDRAQLALRMRFTDDAKRVEIGDKLGITEHGAKNLVQRAKQQLKECVQTKLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INE4</accession>
    <name>A0A518INE4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_05780</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="63"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="102"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="142"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="180"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="205"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="235"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="289"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="289"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="355"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="390"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="423"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="456"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="514"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="535"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="558"/>
            <end position="580"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="580" mass="64215" checksum="0EE120644C07DE05" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INI5</accession>
    <name>A0A518INI5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_05770</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="77" mass="8544" checksum="6BEA8204352C5A6C" modified="2019-10-16" version="1">MIQKPKTESVLDEIHRVRREISDRFHGDIAAIAADANMRAIASGRPIWNPSDNKPMHLSDGENAPELDSQLPPSGDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INK8</accession>
    <name>A0A518INK8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidase C39 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_06200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005074">
        <property type="entry name" value="Peptidase_C39"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03412">
        <property type="entry name" value="Peptidase_C39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="117"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase C39" evidence="2">
        <location>
            <begin position="16"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="141" mass="15769" checksum="B90654E81BA0AF74" modified="2019-10-16" version="1">MPDLRLAFDEQLNGEHTYQQVADAAQKCGLVTQFVSHDTTRLAVGKLPLIAAIRKPNGHMHFIVLFGQRDNKIQVLDSPLPARWIDKNQLITVWNGDGLYCATSVHQLMEEGVKRDFASVPLGGSLLIVFLAIYFGCKFCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INM8</accession>
    <name>A0A518INM8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Flagellin N-methylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_06430</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005358">
        <property type="entry name" value="Puta_zinc/iron-chelating_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03692">
        <property type="entry name" value="CxxCxxCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0966">Cell projection</keyword>
    <keyword evidence="1" id="KW-0969">Cilium</keyword>
    <keyword evidence="1" id="KW-0282">Flagellum</keyword>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="138" mass="15593" checksum="5E36357A8F9FEF5D" modified="2019-10-16" version="1">MAGKPWYKDGLRFECTQCGACCSGEPGYVWVNDDEIAALATHMQMTIDDFEHKFVRNVGAAKSLVEYSDGDCIFLDPDTRGCSVYEARPIQCRTWPFWDSTLEDKAAWKETCDVCPGSGVGKLYNFKQIEARRKEKSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INN3</accession>
    <name>A0A518INN3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">3-oxoacyl-[acyl-carrier-protein] synthase 3</fullName>
            <ecNumber evidence="3">2.3.1.180</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">fabH_1</name>
        <name evidence="3" type="ORF">Mal33_06470</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.3.1.180" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033818">
        <property type="term" value="F:beta-ketoacyl-acyl-carrier-protein synthase III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013751">
        <property type="entry name" value="ACP_syn_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013747">
        <property type="entry name" value="ACP_syn_III_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08545">
        <property type="entry name" value="ACP_syn_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08541">
        <property type="entry name" value="ACP_syn_III_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ACP_syn_III" evidence="2">
        <location>
            <begin position="110"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="ACP_syn_III_C" evidence="1">
        <location>
            <begin position="242"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="337" mass="36948" checksum="FE9A8232A1D18945" modified="2019-10-16" version="1">MPYAQIGPIAVHLPERVETNAQLQAEHPEWDLQVIGEKTGIMQRHISADGETAADLAVKAAEKLFAEHDIDRESVDFIMLCTQTPDYPLPTTACLLQQRLGLSSTCGAIDYNLGCSGFVYGLAMADGLIQSGVARRILLITAETYSKYIDADDRSLRTIFGDAAAATLVQASDEKSLWGFQFGSDGSGADTLLVADGGARAPQDAHKPRHRKRWKSRLYMDGPSLINFTVGAVPKLIEEIVQRNDLTTDDIDLFLLHQATFKMLEQLRISMGVDEARLPIRLRDVGNTVSATVPILIDELRRDGTLSQGSTNVLVGFGVGWSWAGCLWKDTFERAGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INP1</accession>
    <name>A0A518INP1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_06630</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="139"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="178"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="248"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="325"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="362"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="392"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="419"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="450" mass="49540" checksum="F11D7802288C3E95" modified="2019-10-16" version="1">MFNQLQGIVERLQIDRSLAYVLASRIWQGLSGPITILFVVSFLSRDQQGVYYGVFSFVAIQAFFELGLLNILVGYAGHEAAGLESEADGERREQAARRMSELIRASNVWFAIASLLFAIVALAFGWYTLAKTELDSPVAWQLPFAIVVPCAALTVYFAPRMAILEGAGFRESIYRYRFFQAVSGSLAVWISLALGAGIWCLVAATATQTVWAWYISRFRFRDFFDRFTSLVQTATDFSWARDVVPAQWRMALISILHHVTSQCFTIIVLLFHQNAADAGRLGMTLTVTGAIQMLALAWVQTKYPVAAALHGSGEREAAGTMWRRTAAISTSILIAGFAVFILLVVVLPAIDRRFEARFILPSQIAILGVGCLASHLLAVQGFYVLARRIDPLLITVPGLVLAAAAVWAAGYVYSIQGIVVAYAICSTLVVLPMHTWAYLTLRSDDDSVRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INU9</accession>
    <name>A0A518INU9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_07180</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="145" mass="15540" checksum="9205F719DE1CEDEB" modified="2019-10-16" version="1">MGPGLQLLAFTSAVDVASQVGSMARGAVGNFADLVSPQPSSETAESATATSVSLPDLLDRIHAAVTDHLKRLGLPEQTPFQVEVQDDGDLRVLSDSGKRLEIEDAILSDDLLSAEIRQYARQQSPFGDSYSVHWPPLEPSEMLHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPA8</accession>
    <name>A0A518IPA8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_08890</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="59" mass="6794" checksum="E1E79153D0C7B90A" modified="2019-10-16" version="1">MHCVTIPNRHNVWLLDSLATVARRCGLTHLPPADQYHAIGQLTEQRRAEVMRRLEACDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPM1</accession>
    <name>A0A518IPM1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Arylsulfatase</fullName>
            <ecNumber evidence="8">3.1.6.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">atsA_7</name>
        <name evidence="8" type="ORF">Mal33_09850</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="PTM">
        <text evidence="3">The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the sulfatase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.6.1" evidence="8"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004065">
        <property type="term" value="F:arylsulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032506">
        <property type="entry name" value="DUF4976"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024607">
        <property type="entry name" value="Sulfatase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16347">
        <property type="entry name" value="DUF4976"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00149">
        <property type="entry name" value="SULFATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021752477" evidence="5">
        <location>
            <begin position="25"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase" evidence="6">
        <location>
            <begin position="28"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4976" evidence="7">
        <location>
            <begin position="359"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="457"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="479"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="modified residue" description="3-oxoalanine (Cys)" evidence="3">
        <location>
            <position position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR600917-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF16347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV55017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="495" mass="54983" checksum="29F5CBC0536561BF" modified="2019-10-16" version="1" precursor="true">MTIARALRCLMFAIAVCFTPAAFAADKPNVILIFIDDMGWGDIGCYGNDFVDTPRIDQLAAEGMRFTDFYAAGAVCSPTRCALQSGQNQARIGITAHIPGHWRPFERVITPQTTMALPLDTVTVGESMQQAGYKTGYIGKWHLGDSPGFLPDRQGYEYSAVINGPHLPGKFRVAGRKDIKPKPGQYRTDFEADLCVDFIDQNKSKPFFLMLSPFAVHIPLGAMSEKVQKYQDKAEATGRELPNPIYAAMIEHCDDMVGRIVDAVEAQGLTEKTMIVFTSDNGGLYRRYDYRPAADDNVSSLAPLKGEKGSLHEGGVRVPLIVKYPAKVAAGGVCAEPTISYDFYPTFVELAGGSLPANQTIDGVSLLPLLEKPDATLPRSALHWHYPHYHHDRPASSIRERDWKLIEYLDGTGDVELYHIASDIGESKNLVEEKAGRAADLRRKLAIWRHEVSARMPIPNPNYDPQRADQWWNLRSGKPVDSDSRKRFPPTEKDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPS1</accession>
    <name>A0A518IPS1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase-like domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_10650</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="24"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="160" mass="17431" checksum="6D769D5A551AC025" modified="2019-10-16" version="1">MADGSHSSSDSHPLSDAASPAPLSPFHLAVQVNDLAEARKFYGELLGCSEGRSASTWVDFNFFGHQFVCHLNPDKTPGGIHCNEVDGHGVPVPHFGIVLDMQRWSALADRLKSKGVEFVIAPYIRFQGEPGEQGTMFFYDPSGNAVEMKGFNDMDALFAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQ49</accession>
    <name>A0A518IQ49_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">O-Antigen ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_11770</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007016">
        <property type="entry name" value="O-antigen_ligase-related"/>
    </dbReference>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="871" mass="96807" checksum="C31589029BE99230" modified="2019-10-16" version="1"> </sequence>
</entry>
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
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    <sequence length="250" mass="27973" checksum="14D530DE59A9A0CC" modified="2019-10-16" version="1">MNDDPTESESKTRERPEEASLRRRYEELAELAGSLAHEIKNPLSVIHMNSELLSEEIAESDSPIRRRALDKVEIIRQQCQRMENLLRDFLRFARLQSVELTPGSLNDQIDRVLRAYQAQADQSGVEILRYLDNDAPSVMINSDALQAALMNLVKNALEAMEDGGQLLARTYTTKKTVAIDLIDTGCGMDDNTILHMFEPFYSSKNGGSGLGLPTAKKIIEAHGGRISLQSEVGRGTKFTIEFPMPPRLLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQ95</accession>
    <name>A0A518IQ95_9BACT</name>
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        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
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        </recommendedName>
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        <name evidence="9" type="primary">pknB_7</name>
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        <lineage>
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    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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                <person name="Pinto D."/>
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                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
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                <person name="Luecker S."/>
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                <person name="Pohl T."/>
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                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
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                <person name="Overmann J."/>
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                <person name="Kaster A.-K."/>
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                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
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        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
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            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
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            <dbReference type="ChEBI" id="CHEBI:83421"/>
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            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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    </dbReference>
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        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="Prot_kinase_dom"/>
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    </dbReference>
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        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
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    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
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            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
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    </feature>
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            <end position="453"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>ATP</name>
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        </ligand>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV55264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="863" mass="93227" checksum="C0E4DF3050EC783A" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQA1</accession>
    <name>A0A518IQA1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Cyclopentanol dehydrogenase</fullName>
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        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">cpnA</name>
        <name evidence="1" type="ORF">Mal33_12220</name>
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    <organism evidence="1 2">
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        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.1.163" evidence="1"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055041">
        <property type="term" value="F:cyclopentanol dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="264" mass="28158" checksum="A15D80BDBB6ED04D" modified="2019-10-16" version="1">MASHVEDSARLKDRTVVVTGGSSGIGRATCLHMAARGAAVVVHYRQNEAGAEETAEAIRAIGGEASIVQADLQSAADRESLVDICWQRHDRIDSWVHNAGADVLTGGAAKLSFQEKLDLLWAVDVRGTTDLARRVGDRMREQPAAGLPASMVFIGWDQAPHGMEGDAGMMFAPVKSAVMALSKSMAQTLAPDVRVNCVAPGWIRTAWGEVADEGWNRRAIDSSLLQRWGSPDDVAAAIAFLCSPAAAFINAQTLEVNGGWNRKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQD7</accession>
    <name>A0A518IQD7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ferrochelatase</fullName>
            <ecNumber evidence="6">4.99.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Heme synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Protoheme ferro-lyase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 8" type="primary">hemH</name>
        <name evidence="8" type="ORF">Mal33_12890</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the ferrous insertion into protoporphyrin IX.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>2 H(+) + heme b = Fe(2+) + protoporphyrin IX</text>
            <dbReference type="Rhea" id="RHEA:22584"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:57306"/>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <dbReference type="EC" id="4.99.1.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>Fe-coproporphyrin III + 2 H(+) = coproporphyrin III + Fe(2+)</text>
            <dbReference type="Rhea" id="RHEA:49572"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:68438"/>
            <dbReference type="ChEBI" id="CHEBI:131725"/>
            <dbReference type="EC" id="4.99.1.9"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="5">
            <dbReference type="Rhea" id="RHEA:49574"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="6">Porphyrin-containing compound metabolism; protoheme biosynthesis; protoheme from protoporphyrin-IX: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the ferrochelatase family.</text>
    </comment>
    <dbReference type="EC" id="4.99.1.1" evidence="6"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00252">
        <property type="reaction ID" value="UER00325"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004325">
        <property type="term" value="F:ferrochelatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006783">
        <property type="term" value="P:heme biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00419">
        <property type="entry name" value="Ferrochelatase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03411">
        <property type="entry name" value="Ferrochelatase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00323">
        <property type="entry name" value="Ferrochelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001015">
        <property type="entry name" value="Ferrochelatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033644">
        <property type="entry name" value="Ferrochelatase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033659">
        <property type="entry name" value="Ferrochelatase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11108">
        <property type="entry name" value="PTHR11108"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00762">
        <property type="entry name" value="Ferrochelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 6" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="1 6" id="KW-0408">Iron</keyword>
    <keyword evidence="3 6 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 6" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="6">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="283"/>
        </location>
        <ligand>
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV55318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="363" mass="40044" checksum="9B943C69234A44E1" modified="2019-10-16" version="1">MPVTATDLTDATAPAPESLDAFLLISFGGPEGLEDVVPFLENVLRGKNVPHERMLEVAEHYKKFGGKSPINDQNRELLSAVHHELRRAGVQLPIYWGNRNWEPTIADALMSMRDDGKKNGIAFFTSMFSCYSGCRQYRENIADAQKQIGPNAPTIVRLRLGFNHPSFIEAVASRLNDALAVFPEAVRGEVPVLFTAHSIPISMAENCNYVQQLTEASRLVAQQTGSANWELCYQSRSGPPQVPWLEPDICDRIEALHQQAAADGGKLDRLVILPIGFTSDHMEVIYDLDDEAASLCKSLGIEMQRAGTVGTHPSFVRMIRELVEERIGRRDGRATAGELPACEDVCPADCCTYTPTRPGRPRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQH8</accession>
    <name>A0A518IQH8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_13220</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="89" mass="9747" checksum="B1D6F9FD68C65DDB" modified="2019-10-16" version="1">MSETSPIELVVLPDGTIRSIYDEHLDLKSAGRISIARASHVEPSPSGDWLADLSPVDGPKTLGPFDKRSKALAAEVAWLQKNWLTHRAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQW2</accession>
    <name>A0A518IQW2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_14480</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="126" mass="14275" checksum="516498AF2A82212A" modified="2019-10-16" version="1">MTRKRKPRRRMVYSTTAGFYDGSVIACGPERKPSAKRMKEDGIFIDDDGVFKESHYSASYWKTWDVEQRVKAVTILANRLNTRRAIRELVLPEIAAIAATLDRIERRLDAIERSVDGGKSSQGAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IR06</accession>
    <name>A0A518IR06_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Replicative DNA helicase</fullName>
            <ecNumber evidence="3">3.6.4.12</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">dnaC_2</name>
        <name evidence="3" type="ORF">Mal33_14580</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
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        </source>
    </evidence>
    <sequence length="740" mass="81328" checksum="491E1F4209E48A9A" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRT8</accession>
    <name>A0A518IRT8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Copper-exporting P-type ATPase A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">copA</name>
        <name evidence="9" type="ORF">Mal33_17880</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019829">
        <property type="term" value="F:ATPase-coupled cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00371">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021993">
        <property type="entry name" value="ATPase-cat-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027256">
        <property type="entry name" value="P-typ_ATPase_IB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12156">
        <property type="entry name" value="ATPase-cat_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00403">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="SSF55008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="SSF81653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="SSF81660"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="SSF81665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01525">
        <property type="entry name" value="ATPase-IB_hvy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50846">
        <property type="entry name" value="HMA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="217"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="252"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="290"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="314"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="467"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="499"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="830"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="857"/>
            <end position="876"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="8">
        <location>
            <begin position="135"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV55809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="890" mass="93110" checksum="2C9ED04CFD6E8209" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRW4</accession>
    <name>A0A518IRW4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_18180</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011521">
        <property type="entry name" value="YTV"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07639">
        <property type="entry name" value="YTV"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="98" mass="11782" checksum="1A6425BF390F26A7" modified="2019-10-16" version="1">MRPVYERQEKTVTYTVMQPVYEQRTTTRRYTQMNVVRETRTKLDDVTGESIDYVVCKMVPEIKERHIAHTVCKMVPEERTKYVSYTVCRMVRDELIVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRX2</accession>
    <name>A0A518IRX2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Acetolactate synthase</fullName>
            <ecNumber evidence="4 8">2.2.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">ilvB_1</name>
        <name evidence="12" type="ORF">Mal33_18270</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>H(+) + 2 pyruvate = (2S)-2-acetolactate + CO2</text>
            <dbReference type="Rhea" id="RHEA:25249"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:58476"/>
            <dbReference type="EC" id="2.2.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="8">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
        <text evidence="8">Binds 1 thiamine pyrophosphate per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 1/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 1/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the TPP enzyme family.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.6" evidence="4 8"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00047">
        <property type="reaction ID" value="UER00055"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00049">
        <property type="reaction ID" value="UER00059"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003984">
        <property type="term" value="F:acetolactate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd02015">
        <property type="entry name" value="TPP_AHAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012846">
        <property type="entry name" value="Acetolactate_synth_lsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039368">
        <property type="entry name" value="AHAS_TPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012000">
        <property type="entry name" value="Thiamin_PyroP_enz_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012001">
        <property type="entry name" value="Thiamin_PyroP_enz_TPP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000399">
        <property type="entry name" value="TPP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045229">
        <property type="entry name" value="TPP_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011766">
        <property type="entry name" value="TPP_enzyme-bd_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18968">
        <property type="entry name" value="PTHR18968"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02775">
        <property type="entry name" value="TPP_enzyme_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00205">
        <property type="entry name" value="TPP_enzyme_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02776">
        <property type="entry name" value="TPP_enzyme_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00118">
        <property type="entry name" value="acolac_lg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00187">
        <property type="entry name" value="TPP_ENZYMES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7 8" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="6 8 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TPP_enzyme_N" evidence="11">
        <location>
            <begin position="13"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="TPP_enzyme_M" evidence="9">
        <location>
            <begin position="205"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="domain" description="TPP_enzyme_C" evidence="10">
        <location>
            <begin position="398"/>
            <end position="567"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QDV55848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="591" mass="64301" checksum="C9B1421844B64805" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRX8</accession>
    <name>A0A518IRX8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Neutral/alkaline non-lysosomal ceramidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_17820</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
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        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021905300" evidence="1">
        <location>
            <begin position="21"/>
            <end position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="502" mass="54960" checksum="3B6B9385D5B4BB4D" modified="2019-10-16" version="1" precursor="true">MFRHLALCCLFSFTLTIYSAAELRAAELTAGVAKVDITDMQAGPVNDRSYVRALVISDGTTTAAIVTVDAVAIGEIGRIDNEYLGKVRGEVEKSLGISPANVMINASHCHSVVRTDVDELTVQAISQAAAKMVPVQVGVGVGHEDRIMENRRLQLADGRQIDVRHAYSLPPDEAVAAVGPIDPQIGVLRVDTTEGDTLAIVYNFACHPIQGVPGGANTADMTGYASNVIEQNMSDGTVALFVQGCAGDINPIDYKDVDHPRHAQTLGNLLGLSTLQAARKIETRPDATLRVVNETLPLPRADLAQRIIEMEAEREKLVNSLTGTSLNLKTFLPLVVKYRLSEEFPSYYSHRYLHDKALGRSDLRHLDIENRKNMARYINNIHTMEQITRVNTNIRLLRQHQADLVDGGKRMIDVELVGLRVGDFVLTTFPGELTVQIGKNIKQASPHEHTFVAGYTNGYIYYAPTADQLRNVGNAQEDSDCVLAPAWQAIYEAKAAQILSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRY8</accession>
    <name>A0A518IRY8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Lipopolysaccharide export system ATP-binding protein LptB</fullName>
            <ecNumber evidence="6">3.6.3.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">lptB_1</name>
        <name evidence="6" type="ORF">Mal33_18290</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.6.3.-" evidence="6"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03218">
        <property type="entry name" value="ABC_YhbG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030921">
        <property type="entry name" value="LPS_export_LptB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04406">
        <property type="entry name" value="LPS_export_lptB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="6"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="243"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV55850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="283" mass="30880" checksum="B3B32B8B4512CE70" modified="2019-10-16" version="1">MSLAILEAIDLHKTYGRRKVVDGVNLHVNEAEIVGLLGPNGAGKSTSFKMICGMVDPDRGRVCLGGEEVTDWPMFRRARDGGMGYLPQDSSVFKKLTVEQNILALLELLGHNRKQRQARCEELLTEFSITHIRKSRGGKLSGGERRRLEIARCLVSNPRIILLDEPFAGIDPITVQSIQGVIHQLRDSGIAVLITDHAAREILSTVDRCYVIAKGQVLVDGTPDVVKRHPQVQAEYLGDLDAAESHGQSSQTLRHDSPAPAAAAPPASSGLFKSSAPRRRTDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IS73</accession>
    <name>A0A518IS73_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type II secretion system protein G</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">xcpT_2</name>
        <name evidence="2" type="ORF">Mal33_19240</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011453">
        <property type="entry name" value="DUF1559"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07596">
        <property type="entry name" value="SBP_bac_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="367" mass="39496" checksum="686618CB43CC7088" modified="2019-10-16" version="1">MAQRQRLGFTLVELLVVIAIIGILMGLLVPAVQRARETARKTQCANNIRNLGLAAIQYEMRKGKFPGYMQHYGDYASGDPLITDVTPGAHSKFGTWAVALLADLDNQPVYEFWTVNKYSLLSTDSAHSSPDGYDSRKIPNMEIFQCPSDIANSNEEYGKNSYVSNNGTFAAAFPTSVAATPESPANGIFNLNAQPTDTAGVSGVTWSDGLANGPKVRMENIRDSKAQTMLFSENVQARQWYWVTSDPGTNLVAGGLNGISAGAVEASTGSLWWYADSQGAGGATAPSDVVKINGGDIYTETLASGALQLRARPSSFHTGGANAAFADGGMRFINDEIDYRVYQAMMTPYGKGSDVPFKEYVLSDEDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IS76</accession>
    <name>A0A518IS76_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_19350</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNase I family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004536">
        <property type="term" value="F:deoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006308">
        <property type="term" value="P:DNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016202">
        <property type="entry name" value="DNase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00130">
        <property type="entry name" value="DNASEI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00476">
        <property type="entry name" value="DNaseIc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="SSF56219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="56"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="343" mass="38233" checksum="F18585227BDBCAF4" modified="2019-10-16" version="1">MKFVLNLIVVSVIAIIALVKFYEIEGIDGLHLKRRESSAGVVQDLRAMFSSATAEPGSGFSAPGGQPLPSLPGVGVQTVSSRQGAPGTIRLGTFNLREFSREKVNDPKTMDFIVRLLQQIDLIAVQEVDADRRELFPRIVEYLNRDGRTYDFIAGPQVGPDGYQQLLGFIFDRQRVEADLKQTYTVTDPANQIAYEPLVGWFRTVGVDPLDAWTFSLANVYVDPDNPQKELELLTLLFHSIQHDGRGEDDVILAGCFFAGDHELARFASADIRFALEGTPSDIHAQRQTANLLFNRNNTTEFLGESGAIDFLRQYNLTIAEAEAISDHLPVWAEFQIREAIQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISH9</accession>
    <name>A0A518ISH9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Arylsulfatase</fullName>
            <ecNumber evidence="6">3.1.6.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">atsA_16</name>
        <name evidence="6" type="ORF">Mal33_20240</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="PTM">
        <text evidence="3">The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the sulfatase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.6.1" evidence="6"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004065">
        <property type="term" value="F:arylsulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024607">
        <property type="entry name" value="Sulfatase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00523">
        <property type="entry name" value="SULFATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sulfatase" evidence="5">
        <location>
            <begin position="68"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="26"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="modified residue" description="3-oxoalanine (Cys)" evidence="3">
        <location>
            <position position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR600917-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV56045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="789" mass="87576" checksum="C53480DFE55190B5" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISR0</accession>
    <name>A0A518ISR0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_21040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011453">
        <property type="entry name" value="DUF1559"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07596">
        <property type="entry name" value="SBP_bac_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="254" mass="26967" checksum="3E354E43F12C5330" modified="2019-10-16" version="1">MLQFIEGNTLFDQMSWVGRSPGYVNESSPSAGRDVNSPVMRNVLLPHMRCASTTIPEFNGYEMISCYVGISGAASEGASDPFQGNLQQTRSIGGSNGILASNGMLSMNGWYGMRDCLDGSSNVIIMSEMSGVMRYAGSGGSLGQIVLRGASGSDHGWLMGTLEPNRAPGFVNDGNNARCFNITTIRYPVKAAPFSNTVYPGMASNYGPNNPLTSNHPGGAMSLRTDGSVQFLAESTQLLTLKRLASRDDGNPVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISS4</accession>
    <name>A0A518ISS4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_21200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="61"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="105"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="215" mass="24297" checksum="00FA00AD9768332C" modified="2019-10-16" version="1">MGAGWPKRVVCGLGDRELISSGSRRKQPGKDMICHQTLKPKWCRRCRDLTNHEVYEVIPSWLFWSAVIGTLGIAYPLLASIQHRSPNRCAHCDACNNGRYFEKLRRERSPGSRPDKTRRRVKRRRISEVPPADSGGLPRATSRSRPGAPHFATDTSTEREQTTAEICDTSTQRKQTTAEICDTSTQRKQTTAENCDTSTQRKQVIEKQQLQSSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISY0</accession>
    <name>A0A518ISY0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_21760</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="184" mass="21069" checksum="37E7C311FA3FB218" modified="2019-10-16" version="1">MPLFETVQDLDRDAATVRRRYHGVIEARDGRLSSIRLRPWPSLITRLRVWQDTRRRATEARQDVCRLYYDQLWRQPNFLVLKYVVSSSGTSFATARAAALALDAIADLKRSDAIVCEASNARISERLLDRWGWQRHLLSSSRRHYIKRLYPNSRPLTSTGHDLTIFPAIAGPQLAENPSATPAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IT74</accession>
    <name>A0A518IT74_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Helix-turn-helix domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_22690</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041657">
        <property type="entry name" value="HTH_17"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12728">
        <property type="entry name" value="HTH_17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_17" evidence="1">
        <location>
            <begin position="9"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="68" mass="7755" checksum="B90F06DD3CEFE1CC" modified="2019-10-16" version="1">MTEKLSDYLMTAEAAEFLGVSQNTLRTWAKLGKVPVRVNPVNNYRLFRRKDLQAFLDSVAKPVSRKAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IT84</accession>
    <name>A0A518IT84_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Biosynthetic arginine decarboxylase</fullName>
            <shortName evidence="11">ADC</shortName>
            <ecNumber evidence="11">4.1.1.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11 16" type="primary">speA</name>
        <name evidence="16" type="ORF">Mal33_22810</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 11">Catalyzes the biosynthesis of agmatine from arginine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>H(+) + L-arginine = agmatine + CO2</text>
            <dbReference type="Rhea" id="RHEA:17641"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:32682"/>
            <dbReference type="ChEBI" id="CHEBI:58145"/>
            <dbReference type="EC" id="4.1.1.19"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 11 12">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="11">Amine and polyamine biosynthesis; agmatine biosynthesis; agmatine from L-arginine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 11">Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.19" evidence="11"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00186">
        <property type="reaction ID" value="UER00284"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008792">
        <property type="term" value="F:arginine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006527">
        <property type="term" value="P:arginine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008295">
        <property type="term" value="P:spermidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06830">
        <property type="entry name" value="PLPDE_III_ADC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.37.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01417">
        <property type="entry name" value="SpeA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009006">
        <property type="entry name" value="Ala_racemase/Decarboxylase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040634">
        <property type="entry name" value="Arg_decarb_HB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041128">
        <property type="entry name" value="Arg_decarbox_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002985">
        <property type="entry name" value="Arg_decrbxlase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022657">
        <property type="entry name" value="De-COase2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022644">
        <property type="entry name" value="De-COase2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022653">
        <property type="entry name" value="De-COase2_pyr-phos_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000183">
        <property type="entry name" value="Orn/DAP/Arg_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43295">
        <property type="entry name" value="PTHR43295"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17810">
        <property type="entry name" value="Arg_decarb_HB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17944">
        <property type="entry name" value="Arg_decarbox_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02784">
        <property type="entry name" value="Orn_Arg_deC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001336">
        <property type="entry name" value="Arg_decrbxlase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01180">
        <property type="entry name" value="ARGDCRBXLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01179">
        <property type="entry name" value="ODADCRBXLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="SSF51419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01273">
        <property type="entry name" value="speA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00878">
        <property type="entry name" value="ODR_DC_2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00879">
        <property type="entry name" value="ODR_DC_2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="10 11 16" id="KW-0456">Lyase</keyword>
    <keyword evidence="7 11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 11" id="KW-0620">Polyamine biosynthesis</keyword>
    <keyword evidence="11 12" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11" id="KW-0745">Spermidine biosynthesis</keyword>
    <feature type="domain" description="Orn_Arg_deC_N" evidence="13">
        <location>
            <begin position="89"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="domain" description="Arg_decarb_HB" evidence="14">
        <location>
            <begin position="372"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="domain" description="Arg_decarbox_C" evidence="15">
        <location>
            <begin position="580"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate-binding" evidence="11">
        <location>
            <begin position="285"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="11 12">
        <location>
            <position position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00002257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR001336-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF17810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF17944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="QDV56299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="635" mass="71465" checksum="13502E19586E9980" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITF9</accession>
    <name>A0A518ITF9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF1080 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_23460</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010496">
        <property type="entry name" value="3-keto-disaccharide_hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06439">
        <property type="entry name" value="DUF1080"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022049200" description="DUF1080 domain-containing protein" evidence="1">
        <location>
            <begin position="27"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1080" evidence="2">
        <location>
            <begin position="39"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="217" mass="24322" checksum="67DDAFB6283CF541" modified="2019-10-16" version="1" precursor="true">MNRLTRNTAVAAFSIFAALCSSVAVTAEENKSSDDEAAWISLFDGKSMEGWEKVGSDGSKWEVKEGAIWGSGTPSMLVNTTGPYKNFRYRAEVKINDGGNSGLYFRTTRRPGFSDGYEAQIDSTHTDPIRTGSLYGFCHVYPQLVKPGTWFTYEIEVRDDVWRGREMTRIKITVDGNELYEYLDFEKNYGPGHFAFQQHDPGSTVAIRKAEVQPLAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITL3</accession>
    <name>A0A518ITL3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">AI-2 transport protein TqsA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">tqsA</name>
        <name evidence="7" type="ORF">Mal33_24080</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002549">
        <property type="entry name" value="AI-2E-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21716">
        <property type="entry name" value="PTHR21716"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01594">
        <property type="entry name" value="AI-2E_transport"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="37"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="59"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="88"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="193"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="239"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="267"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="302"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="344"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV56418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="400" mass="43290" checksum="A3778FA029CA56B5" modified="2019-10-16" version="1">MGSVSFEAAIASPLGAFLVFSFSMIPKDPTTDTRVQTVCLMALAVVAVTFSIYWLRPVLVPLVVALIVVSGVSPILTTLERRLGVNRLIAAGLTFVSGVGLMIAFGVSVWMSMVDLNANSEMYRVRVQEIVDWAELRVEAIGSRMEEEAALFLPTRELSVDVTKSPEVDKANEPTMRDASEFVDAFIRDGISIISQAFISLVSTCAIVMIYVFFLLIGTPTVGDDWPMVREIDQQIRSYLGLKTIISIFTGLAFGLALRMFGVPMAFTFGVLAFLLNFVPNIGPLVASLLPIPLILLNPEGSIGWMASAIVVTCGIQGISGNLIEPKIMGNSSDLHPVTVLVALMFWGMMWGVIGMFLATPITAAMKILLQRIDSTRPLADLMAGRFSANGDAEDRSLVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITN9</accession>
    <name>A0A518ITN9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cation efflux system protein CusC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">cusC_2</name>
        <name evidence="6" type="ORF">Mal33_24200</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010131">
        <property type="entry name" value="RND_efflux_OM_lipoprot_NodT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01845">
        <property type="entry name" value="outer_NodT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0564">Palmitate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1134">Transmembrane beta strand</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="31"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="503"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="397"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV56430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="550" mass="60156" checksum="541075AA90BBA7D3" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITT1</accession>
    <name>A0A518ITT1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_24840</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="88" mass="9341" checksum="269DBD60342F5148" modified="2019-10-16" version="1">MTTHALTPSNGGVCFSTKIKAVLSVALFWCTPVSAIVSIVAVRATSGTSGWPREVARTGAFLTIGWVAYLTVAIAWMLYVIVWNPALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITU5</accession>
    <name>A0A518ITU5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_25050</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021508">
        <property type="entry name" value="Gp17-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11367">
        <property type="entry name" value="DUF3168"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="136" mass="15387" checksum="33CCC0905C3097B5" modified="2019-10-16" version="1">MIVDVQQFVTAWLNTDATINGIVAKRITADELDKQKVYPAIRHTIITTTEDTDLDGNAVALHSRIQIDCLALNRHQANALCRLVRNRLRGYWGTYDGFLVHGLIPVDAQRNQYTQPKPSVQGIRAAIQDFRISYQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IU20</accession>
    <name>A0A518IU20_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Flagellar biosynthetic protein FliQ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">fliQ</name>
        <name evidence="8" type="ORF">Mal33_25790</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FliQ/MopD/SpaQ family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002191">
        <property type="entry name" value="Bac_export_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34040">
        <property type="entry name" value="PTHR34040"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01313">
        <property type="entry name" value="Bac_export_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004669">
        <property type="entry name" value="FliQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00952">
        <property type="entry name" value="TYPE3IMQPROT"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0966">Cell projection</keyword>
    <keyword evidence="8" id="KW-0969">Cilium</keyword>
    <keyword evidence="8" id="KW-0282">Flagellum</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="14"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="51"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV56587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="89" mass="9644" checksum="BBBF07BCB6C37A97" modified="2019-10-16" version="1">MDANSAADFVREALLQAVIIASPLLFMGMAAGLIIGLVQALTQIQDQTVSFVPKILAMATTMIVCMPWMIQRMVEFARELYISAGQIGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IU28</accession>
    <name>A0A518IU28_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glycosyl transferase family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_25880</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00316"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025993">
        <property type="entry name" value="Ceramide_glucosylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12726">
        <property type="entry name" value="PTHR12726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="278"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="308"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="351"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV56596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="410" mass="45279" checksum="D124069C75FEDB80" modified="2019-10-16" version="1">MTIVSALYCLIALIVAIQTTAAVCFVWFMSRSGRDRQASDQPKAAIILCLRGADPFLSDCLQSLLSQDYANYLLCVVVDSDEDPAWSVLRKFEGRAGLQIEVLQNPPPTCSLKCSSLVQAIGNLDASFQIVALCDADAVPGPNWLADLSAPLTDPDVGVATGNRWYVPQPNSAGSMIRYLWNVPAAVNMVLLKIAWGGSLAIRRDVIAKTDMLNHWSGALCEDTILYRLLRKHGFRQAFVPDAMIVNRESTTLGSVLDWVPRQMLLAKLYHPSWPATVGYGSISIIVPFLAALLIVVTAIQSNLRETMGVLVAVAAFEVSNALLVGLCQWGVRRRLASRAAEWKSWGWRSIAALPFWVLLSQLISPVFYWKCFTARSIQWRAVRYDIAGLRITKHPHSSYRPNTDASQSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUI6</accession>
    <name>A0A518IUI6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">RNA polymerase sigma factor RpoS</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rpoS_1</name>
        <name evidence="8" type="ORF">Mal33_27280</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000943">
        <property type="entry name" value="RNA_pol_sigma70"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007630">
        <property type="entry name" value="RNA_pol_sigma70_r4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04545">
        <property type="entry name" value="Sigma70_r4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00046">
        <property type="entry name" value="SIGMA70FCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="6">
        <location>
            <begin position="132"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4" evidence="7">
        <location>
            <begin position="242"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="108"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV56730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="307" mass="34685" checksum="7E2E4ED91E85FE78" modified="2019-10-16" version="1">MRGRESAGSLTPSIHLLEIDLGRSDIAYIPNEDFDTASEQDFAEIDGQLYADEEESGRSRRDAEAFLMAIEASRLLTVEGERFLFKRLNFLRFRANALQASLGRGRAAKRSQQEIDRLLCEANQTRDQIACANLRLAASIVRKYSNSQDDFDEFLAEANAILLNAVDKFDYSRGYRFSTYATHAIQRHIYRLLQKTRKARDRQTADGNDQILQIEASPYVGEAACEDAAKAMKKLIASFDRVLDDREQEIVRRRFGLNASGKGASMRAIGDELGISKERVRQLLNSSIEKLAKIAEPLESILQQDRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUK7</accession>
    <name>A0A518IUK7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_27740</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="547"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="572"/>
            <end position="595"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="683" mass="75185" checksum="9D6B969F5D048D09" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUM3</accession>
    <name>A0A518IUM3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative efflux pump membrane fusion protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_27910</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="446"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="476"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="506" mass="54531" checksum="2F7AE0B22911E932" modified="2019-10-16" version="1">MNEQEAPYRAPLTTAGRRRGGGIQVALATMLLVAVAIGVGLAASSMQRSDHPATDRSPGESSRPHTAARNASTLPVETMQVQRVESYARERTFTGIIKPARQSELSFERLGEVVEVSADLGDRVEKGQPLARIGDRRLKVKRLGLEAQHREALAVLAELEAGPRKESIAAQRATVQDLAAQVDAADQMAKRRQRLLLASASSREEAEQAAFSLTAVEARLQSAQKVLDELTAGTRQERLDAQKAIVAQFDASIQDVDIEIEKSQIVAPYDAFVTERSVDEGSIAQPGSTIFRIIEDTSLEVWVGVPTTIAASIQAGEKLPVIVRDQSFDATVRSRIADLDHQTLTQTIVLTLDDVSPQQIVPGEVARLAFTQEIPVDGFWIPLAAISRGGQGLWSVLAVVGDGDATTTTERRDVDLIETQGERALVRGTLETGDWIVSSGTHRLTTKQAIRVPEPTDEVDESATAPATEPASQDVMPPAEKPPEPLDLVPTPRSDRPIASLTPTAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUT9</accession>
    <name>A0A518IUT9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_28620</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="258" mass="27997" checksum="40DCF37DF2B2F06A" modified="2019-10-16" version="1">MIQRPPILLLLAGGLVGGPYVATETELGQSLQAKLTQVTASGGDAQTAGWTSPSADGLDSHYSTEALWARGDKHPHRDLDWLSHPSQALAGGPFQDFRDVLRFDATPAWVTAQFSRVTTVLADRQLEGLRVPVVTGAKPDDLAGTITYYFTPQHRLQRISFNGFTGDPTRLVSLMLAHYHLSPDHSLGSGGYSYGWNGTPSSLMKITPTPVIYSESPNSRFTVFLELNQPNGPYGLSHAATDILSVSRTSQTPQRTSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUU6</accession>
    <name>A0A518IUU6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">TadE-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_28670</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012495">
        <property type="entry name" value="TadE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07811">
        <property type="entry name" value="TadE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="138" mass="14735" checksum="CC7CF70BB00AD6FB" modified="2019-10-16" version="1">MIQQSPIQRPRAKSRRGTAIVEFAVCLPLLALLVFGTIEAASRIFLKQTLSISAYEAARQAIRVGSTTENSKASGDSILTARKVKGSQIVFSPADITNASRGELISVSVSAPTRDNSQVLGKFIADKTITATVVMVKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IV45</accession>
    <name>A0A518IV45_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_29570</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022242214" evidence="1">
        <location>
            <begin position="24"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="185" mass="20442" checksum="16606E748C3C8826" modified="2019-10-16" version="1" precursor="true">MRFTARFIAAITIAASATATANAQQVAGEYIVDSQIISDVAVGEETGESHQASASGQCTNCQADGASGGTLRGNGHLASMVRGGQQGPYIPKQYAQPDLFYNYYSNGQNQVNAEMYLAPGPVPAFVGHTWVPYQPLMPHNYLYQHQDRYHNHYDYGRGTNRTKASYRVAPKQYAQTMYNFFRIAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVP1</accession>
    <name>A0A518IVP1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Undecaprenyl-phosphate mannosyltransferase</fullName>
            <ecNumber evidence="2">2.4.1.54</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_31480</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.4.1.54" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047267">
        <property type="term" value="F:undecaprenyl-phosphate mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="11"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="250" mass="27811" checksum="7C7C4CE07B292106" modified="2019-10-16" version="1">MTAPDKWLCALPVYNEVNFVDEVLDNVANYAANILVVDDGSNDGTDARLAQRTDVTVVRHPENRGYGAALTTAFEYAIDNGYDVVVTIDCDGQHQPVRIPDFVAAASQADIVSGSRYLAMSEDDDAPPEERMLINRKITQQLNRRLGLKLTDAFCGFKAYRVDALRKLRITDPGYAMPLQLWVEAALADLSVVELAVPRIYLDLSRSFGGSLDHAETRLAYYNRVLEDAITSACREGRKLPRRRELCPDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVS6</accession>
    <name>A0A518IVS6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase</fullName>
            <ecNumber evidence="11">2.4.2.43</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">arnT_1</name>
        <name evidence="11" type="ORF">Mal33_31920</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.4.2.43" evidence="11"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0103015">
        <property type="term" value="F:4-amino-4-deoxy-L-arabinose transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038731">
        <property type="entry name" value="RgtA/B/C-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13231">
        <property type="entry name" value="PMT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 11" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="278"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="354"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="379"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="434"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="479"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="526"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="564"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="589"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="630"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="656"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="683"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_2-like" evidence="9">
        <location>
            <begin position="33"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="PMT_2" evidence="10">
        <location>
            <begin position="333"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QDV57190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="815" mass="91014" checksum="A6D215849BA27BF3" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IW50</accession>
    <name>A0A518IW50_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphoribosyl-AMP cyclohydrolase</fullName>
            <shortName evidence="7">PRA-CH</shortName>
            <ecNumber evidence="7">3.5.4.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">hisI</name>
        <name evidence="9" type="ORF">Mal33_33220</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>1-(5-phospho-beta-D-ribosyl)-5'-AMP + H2O = 1-(5-phospho-beta-D-ribosyl)-5-[(5-phospho-beta-D-ribosylamino)methylideneamino]imidazole-4-carboxamide</text>
            <dbReference type="Rhea" id="RHEA:20049"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58435"/>
            <dbReference type="ChEBI" id="CHEBI:59457"/>
            <dbReference type="EC" id="3.5.4.19"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="7">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 3/9.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the PRA-CH family.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.19" evidence="7"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00008"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004635">
        <property type="term" value="F:phosphoribosyl-AMP cyclohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.810">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01021">
        <property type="entry name" value="HisI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026660">
        <property type="entry name" value="PRA-CH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002496">
        <property type="entry name" value="PRib_AMP_CycHydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038019">
        <property type="entry name" value="PRib_AMP_CycHydrolase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01502">
        <property type="entry name" value="PRA-CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141734">
        <property type="entry name" value="SSF141734"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="5 7 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="PRA-CH" evidence="8">
        <location>
            <begin position="32"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="79"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV57318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="137" mass="14861" checksum="9C2F3E7AC4EE02DB" modified="2019-10-16" version="1">MTDAPAIPDFSRGVDGLLPAIAQDADSGRVLMLAWMNPQAWQETLETGQATYWSRSRGQLWRKGETSGHRQRVTEIRVDCDADTILLSVEQTGAACHDGFASCFYRAIQTDGTAKVADSRLVDPNDVYGKGSNAPSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWB4</accession>
    <name>A0A518IWB4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_33810</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027602">
        <property type="entry name" value="PGA_system"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04332">
        <property type="entry name" value="gamma_Glu_sys"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="355"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="405" mass="44047" checksum="83C61CC7DC2B213B" modified="2019-10-16" version="1">MNRQSFLKMNPAQPFQVMYWRPKKISRRWLWAGMLASLAGLFAVEWWPQQVAAPSPQLTAAAEKANEALRHIKDLRIAQGHRALPKLDPSGSHLIGPSMSMVTSKLGSLESKQTSINPNLAAVVVRWLEQAGVEPGDSIAIGASGSWPALNIAVYAAAETLQLKPTIVLSVASSQYGANSPDMMWVDMERQLRDAGIFPESFAAKSASLGGLFDRAAGMTEPTREMLELAATRNGIPVLDVADIEDSVGQRMEIYQNASSDQPYAAYINVGGGSASIGGTAGNACFSAGVHRTTPSDQEVPDCVASRMLTQGIPIVNVVDAKQIAESYGLAIAPAQMPRVGQGSLFSHMTYRRPLAAALICMTWVWMSVTVFPRWYLRTVLKLRRLVRRPNVSTNALPKQVEWMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWC5</accession>
    <name>A0A518IWC5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Macrolide export ATP-binding/permease protein MacB</fullName>
            <ecNumber evidence="9">3.6.3.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">macB_5</name>
        <name evidence="9" type="ORF">Mal33_33490</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="3.6.3.-" evidence="9"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="300"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="349"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="411"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="8">
        <location>
            <begin position="21"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="7">
        <location>
            <begin position="334"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV57345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="447" mass="48876" checksum="8C88E3A1F1037920" modified="2019-10-16" version="1">MLLLRTFRLGVKSLMLHPLRSGLTMLGILIGVAVVIALTAISNGASRVVQEQIESLGADTIIVRTVKPPSDVFAGRSAVPYGLSRDELDLLIATVPTIRSALPIREIKRQFMYRDRSIDGRLVGCTPEYADVTKLELQPGPEGASGQFITDLNNLKRDSVCVLAAKVAEKLFPFENPIGKRIYLPEHTDFYRVVGVLKHRTASAAIGGSLDSQDFSSDVYIPLKTLEQRIGDTIVTRGSGSFSMDIVELNQITLKIDKVSNVRTTAAFIEDLLGPRHTALNDISVVFPLELLEQAENMRLMFIGIGVLIAFISLFVGGIGIMNIMLASVTERTREIGIRRALGAKRADIVWQFLVETIVLSFVGSLLGIVLGLLSPWMYDGMRLLATEFIPEKLAALPEAIREARPQIVELSIPIAVVIAMGVGILSGLYPAIRAARMNPIEALRHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWE4</accession>
    <name>A0A518IWE4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Capsule biosynthesis protein CapC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">capC</name>
        <name evidence="2" type="ORF">Mal33_33800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045227">
        <property type="term" value="P:capsule polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008338">
        <property type="entry name" value="Capsule_biosynth_CapC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14102">
        <property type="entry name" value="Caps_synth_CapC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01759">
        <property type="entry name" value="CAPSULEPROTC"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04011">
        <property type="entry name" value="poly_gGlu_PgsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="103"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="154" mass="16658" checksum="EF4B5C4E1E27F990" modified="2019-10-16" version="1">MDTTLLAIAIGLVVSLLVTEVFGLSVGGMIVPGYIALSMHHPIAVVMTIVAALVTWGIIRQVSRWVILYGRRRVVLTMLFGFVVGTMFRLLANSLAGVPAEDAMNPVVMIGFIIPGLIALWFERQGFIETLSPMMSAAVLVRLTLITIGVENFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWG3</accession>
    <name>A0A518IWG3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Protein-glutamine gamma-glutamyltransferase</fullName>
            <ecNumber evidence="4">2.3.2.13</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">tgpA_3</name>
        <name evidence="4" type="ORF">Mal33_34420</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.3.2.13" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003810">
        <property type="term" value="F:protein-glutamine gamma-glutamyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002931">
        <property type="entry name" value="Transglutaminase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01841">
        <property type="entry name" value="Transglut_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00460">
        <property type="entry name" value="TGc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="38"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="75"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="105"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="142"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="179"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="211"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="664"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="domain" description="TGc" evidence="3">
        <location>
            <begin position="540"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="242"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV57432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="790" mass="86043" checksum="A35FC5E64F5C8757" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWK9</accession>
    <name>A0A518IWK9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Thiol:disulfide interchange protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_34730</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012336">
        <property type="entry name" value="Thioredoxin-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13098">
        <property type="entry name" value="Thioredoxin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin-like_fold" evidence="1">
        <location>
            <begin position="46"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="144" mass="15846" checksum="8C8E0210C9515FB5" modified="2019-10-16" version="1">MRKPQIGSVLIGAVIGCSLMLAQSEASGEIRWINSVRQAQQKWSASRKPLLVYVTSESCFFCKKLDQATWMDPSVGDLVKERFVKLKVNGQRNHAIAQQLNVTAFPTVIVLSADGQVLGRRDGFVEPTEMSAFLQTVAPATTLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWR2</accession>
    <name>A0A518IWR2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphonoacetaldehyde hydrolase</fullName>
            <ecNumber evidence="2">3.11.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">phnX</name>
        <name evidence="2" type="ORF">Mal33_35150</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.11.1.1" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050194">
        <property type="term" value="F:phosphonoacetaldehyde hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019700">
        <property type="term" value="P:organic phosphonate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01375">
        <property type="entry name" value="PhnX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006323">
        <property type="entry name" value="Phosphonoacetald_hydro"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01422">
        <property type="entry name" value="phosphonatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0704">Schiff base</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="280" mass="30346" checksum="195EC1E18E2990C3" modified="2019-10-16" version="1">MNNETANPIRLVVVDWAGTTIDFGSQAPAAAFTSVFAARGIEVSGDESRAPMGLNKREHLIAMLRQPEIAKRWREVYQKDWTEDDIDAMYHEFVPLQLKAIEQFAQLVPQLTETVQQLRDRNLQIAGTTGYFRAAAEAVAERAAAAGFVPDTNICADDVPQGRPAPWMIYRAMERLGVYPPAAVVKVGDTVADIQSGLSAGCWSIGVCDSSSLTGLSVEQFAALTEDQRRDQLAQTAAAFRAAGSHAVIDSIADLPALIDTINARSLEYPQVIDPVSATL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWT9</accession>
    <name>A0A518IWT9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Class III cytochrome C family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_35640</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029467">
        <property type="entry name" value="Cyt_c7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020942">
        <property type="entry name" value="Cyt_c_III_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036280">
        <property type="entry name" value="Multihaem_cyt_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039118">
        <property type="entry name" value="QrcA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39425">
        <property type="entry name" value="PTHR39425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02085">
        <property type="entry name" value="Cytochrom_CIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14522">
        <property type="entry name" value="Cytochrome_C7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48695">
        <property type="entry name" value="SSF48695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Cytochrom_CIII" evidence="2">
        <location>
            <begin position="46"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome_C7" evidence="3">
        <location>
            <begin position="137"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV57554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="228" mass="25144" checksum="7C4C79D9AE2136E4" modified="2019-10-16" version="1">MDRFLFPRWVNRFLMLMGALVAGGGAYAGVVFIGATDPGTLNTGYQPDQPIPFSHAIHAGQLRMDCRYCHNTVFDAALAAVPPTATCINCHSPADEAGQTALSAVHADSPKLKPLHQSWETGKSVGWKRVHNLPDFVYFNHAAHVNSGVSCVRCHGRVDKMDVVYQAKELSMAWCLDCHRGVDPADIRPVEFVTKLDWKSDEDPIALGEKLIKEKNIHPQTNCAVCHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWU8</accession>
    <name>A0A518IWU8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Caspase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_35800</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004197">
        <property type="term" value="F:cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029030">
        <property type="entry name" value="Caspase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001309">
        <property type="entry name" value="Pept_C14_p20"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52129">
        <property type="entry name" value="SSF52129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50208">
        <property type="entry name" value="CASPASE_P20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021980953" evidence="2">
        <location>
            <begin position="27"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="domain" description="CASPASE_P20" evidence="3">
        <location>
            <begin position="53"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="439"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="482"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="482"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="535"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="557"/>
            <end position="573"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV57569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="600" mass="66118" checksum="478181BB018FC403" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWV3</accession>
    <name>A0A518IWV3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_35850</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="307" mass="33666" checksum="5DF6450D4A1292D3" modified="2019-10-16" version="1">MPPALFDPSPAFQFEPISEAHSSPKPQRLDLAGAMSIAASEPATQNILSGVQRIPTFLSSSPSGVDHRIVRYDVPLTEVTAHNLFRASGVQGKLMDVPSDDPEQETIRVVRYEVPDDEILLHSTISQNGLQGDLVEVHDDQSWRPQVRFLQPKARVFFDMKRDNDSEFDLFRNGSILASLDVLEIYKPLKLVTDFFADENSKKVSLHDLGWRFGATLGLGITTALSNGGTDGGGAPIGVGSIGFRYEFPIGPEPPAVLDQNGRPIRLDQRTRVGFEAGLQAGTSTDETIADRFDVGFYLGMLVNTPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWX8</accession>
    <name>A0A518IWX8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Outer membrane protein assembly factor BamD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">bamD_2</name>
        <name evidence="2" type="ORF">Mal33_36050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13174">
        <property type="entry name" value="TPR_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="123"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="403" mass="45649" checksum="1FBCA828103A0027" modified="2019-10-16" version="1">MRMNIYTLLAIGLIAVPGCQSFQNTPWSDGLVAQELPPPTEATDADQIAEIEDKRNPAVALTDYVTGKGPANRPKARELYREGEALFEQAAAAEGKPRMKQFRQAAASFIKASKEWKDSALEEDALMMAGESYFFADDFPEADKMYGELLESHPRSRHIDRVVARRFEIAKYWLAVDKQSPQILPVNLTDHRLPALDVDGSGIKLLDQIRYDAPTGKLADDATMAAGLEYFERQKWTTADGFFSDLRESFPDSDHQFNAHLFGLKCKLKIYQGPKYSGTVLNEADDLVKRMQRHFATELQKPENRELVSKAAAEIDHLLAERLYSRAQFRELRSEHGAAKFYYRQLIQDHPKTSYADTARERLTAIEGKPDTPPQRLAWLHKMFPDSEPAKPIMVGNPSNMLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWZ5</accession>
    <name>A0A518IWZ5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_36070</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="106" mass="11927" checksum="A0AB1A9E5C103A4D" modified="2019-10-16" version="1">MSRREQIEAMLKDEPQDTFLRYSLAMELRSEGDNEASIRQLVEMTGDTPPYVPAFFMAAQQLVDLDRTDEARSMLRDGIEQARAQDDAHAAAEMADFLAMIGDLGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IX02</accession>
    <name>A0A518IX02_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_36330</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="154" mass="15843" checksum="4722B06E36E093EA" modified="2019-10-16" version="1">MKFGRLLSVVFVASIVATFTIGCDGGTPLADVYPASGRVLVDGKPVEGISVALLPEAGVAGRGGFGVTDASGAFSLTSVEGQEGVREGKYKVIFTKLALPDGSPIPEGASAADVGAENILPPAYGNPDMSTMYTTITAGTNPEMEFELDSKRKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IX46</accession>
    <name>A0A518IX46_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_36680</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="126" mass="14367" checksum="675B3725970AB4AE" modified="2019-10-16" version="1">MRDLREQEKPSTDVPMSVLMCWRDALEVPLAELLVEPDMRLSQSIAHRAKLVRMMKTILTLCEHGGDERTQRLVTMLREQMLELMPELTEVTGWPSMGSRRSQDELGRIGQQPISLDGFSSDVLAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IX85</accession>
    <name>A0A518IX85_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">4-hydroxybenzoate octaprenyltransferase</fullName>
            <ecNumber evidence="5">2.5.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ubiA</name>
        <name evidence="5" type="ORF">Mal33_37100</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.5.1.-" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016765">
        <property type="term" value="F:transferase activity, transferring alkyl or aryl (other than methyl) groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13959">
        <property type="entry name" value="PT_UbiA_COQ2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006371">
        <property type="entry name" value="HB_polyprenyl-transferase-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039653">
        <property type="entry name" value="Prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000537">
        <property type="entry name" value="UbiA_prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044878">
        <property type="entry name" value="UbiA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11048">
        <property type="entry name" value="PTHR11048"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01040">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01475">
        <property type="entry name" value="ubiA_other"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="49"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="98"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="123"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="146"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="177"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="222"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="251"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="283"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV57697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="306" mass="32430" checksum="16BD13A7F4F01270" modified="2019-10-16" version="1">MAQPSKLRMMLEMIRFSHTIFALPFAALATVMAIKLPLPDGAAVRVRPLDLVAILICMVAARSVAMAFNRLADQAIDAGNPRTAGRHLPAGLLGRHEVTIFAILCAVGFLVGCALFLPNWLPLAASIPVLMFLCGYSLAKRFTAAAHLWLGVALSLAPICVWAALRGSAVLADPSDLLPAVILAAAVALWVTGFDIIYACQDEAFDRSEGLQSVPARFGAKGAFRIAAACHAGMVLVLLVLPSVVPALGLGWIYYAAVGSIAALLIYEHCLVRPDDLDRINQAFFQVNSIVSVGLLVAAGIDCWMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXB2</accession>
    <name>A0A518IXB2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NfeD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_37310</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
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        <property type="entry name" value="NfeD-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01957">
        <property type="entry name" value="NfeD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="55"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="NfeD" evidence="4">
        <location>
            <begin position="106"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="164"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV57718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="199" mass="21255" checksum="EFC91868F0762EFD" modified="2019-10-16" version="1">MDGPLFWSFALLAAGLLLIIVEFFVPSGGVLAIASGLTLVGSIVVGFSVSPRWGMIMVVLVAVIVPVVLGMTVRLWPRTPMGRSIMARQPGDPLPDVLPDDDFHRKIKSLQGRVGVAASDMLPNGTIKIDGEKFDAVSSGGVIDRGQNVEVFRVDSGKLHVRATSRPVEENRGRIEPPGSPLDQPIEQLGIDSLEDPLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXJ2</accession>
    <name>A0A518IXJ2_9BACT</name>
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        </submittedName>
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    <gene>
        <name evidence="5" type="primary">sir_1</name>
        <name evidence="5" type="ORF">Mal33_38250</name>
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        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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    </organism>
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
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    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050311">
        <property type="term" value="F:sulfite reductase (ferredoxin) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005117">
        <property type="entry name" value="NiRdtase/SiRdtase_haem-b_fer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036136">
        <property type="entry name" value="Nit/Sulf_reduc_fer-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006067">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045169">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045854">
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        <property type="entry name" value="NO2/SO3_Rdtase_FeS/sirohaem_BS"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="71"/>
            <end position="123"/>
        </location>
    </feature>
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        <location>
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            <end position="331"/>
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    <feature type="domain" description="NIR_SIR_ferr" evidence="4">
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            <begin position="366"/>
            <end position="435"/>
        </location>
    </feature>
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        <location>
            <begin position="453"/>
            <end position="587"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV57810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="592" mass="64899" checksum="746752081CB1AFF2" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXN0</accession>
    <name>A0A518IXN0_9BACT</name>
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        <submittedName>
            <fullName evidence="2">Internalin-A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">inlA_2</name>
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    <organism evidence="2 3">
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    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
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                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
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                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="3"/>
    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="392" mass="43128" checksum="C9A0051537937709" modified="2019-10-16" version="1">MIVYGNRHLCLPQNPRQYLMVNTRITGWLAITCLMLGTTLADDKAAEPAKPAAAAEAKPEAKKPEEKKDVKPEAKKEAKPEAKAEPKKEDKPEPKKEAKPEPKKEAKPAPKKEAKPAAKPKEMKAEAKPEEKKPEAKPAPTFPDKALEAAVRAEVFAKRYNNEPITAEDVKNISRVVGKGKGIKSLEGLQHCKAIMLIDLEDNEISDLGPIKDLTRLQSVTLAGNKISDIKPLAGLVKMQLLDLSRNQVSDLAPLKAMSNLRTLYVADNKLATLAPIAELTKIWSLDAAGNQISDLSPLSNLGWLTTLDIQRNAVSDLSPLKSLDDLDFMLLQDNKIADLSVLVEMCKKDFEGSKRFAPFLKLYVKGNPLSDDAKKQQLAKLKEFGTRVHAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXN6</accession>
    <name>A0A518IXN6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_38660</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetes</taxon>
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    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="84" mass="9823" checksum="1807F1CD6D603E36" modified="2019-10-16" version="1">MAEQHSRHQEKIIKNYYRNRDQIALQRSQELVTELYLTTGKKREQVWKNLAGHLEKLGLPAAQITHLQEQDDPAVIAEVIQKYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXR3</accession>
    <name>A0A518IXR3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_38950</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="258" mass="29107" checksum="F31384F12DC1CA1E" modified="2019-10-16" version="1">MSTSPPSSFDQAWQFYHRGEYAEVVGKLQPRSEELSAEELQLLGLALHDLGRPLEAADAIEKASLICPVSDEVRIALASCYAQLRRTDLARELYLQLALSRKLPPALMLRIAAGLEAIDAPQLAMQVCEWITEQDDSIAQAYYDMGRYAACAGQPLYITEVLTIRALQLEPQNVQFRVGLVSLLIQLRRDDEAIRELLLLSRSDLQQVRCFSCLERIAEMLQRHGHTALARDCRAQVARLRSVDRNDPPTNIHREAKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXT5</accession>
    <name>A0A518IXT5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_39180</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="26"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="342" mass="36401" checksum="AC8FEC8524CF6233" modified="2019-10-16" version="1">MIRGIFHHRSTTTACRRQATRRGFTLFEVVVALGLSVVLMGMIGFAMQFYAAQLNVRDSEARRTQLARAILRMIAEDLQACIYPQEFDAGALAEVLASSATGAAAGGSSGSSSSSESDAVTVEEGEEMEATAISDSLASTVRPGLIGNQYQIQFDVSRLPRMEEYLPMLTNPTDVGIQDMPSDVKTVAYFVQQANLSGVGDSIGQLGSGGATNLQSSSGLVRRALSRELTTYASESGDVMRLNQTGDVLAPEVLQIEFAYFDGTQWIYEWNSDESQGLPIAVQIRLTLGKPPGSAEDPMNAGLATAGDATTGDVYDLMVRLPMAQLVSEEEATATDLSAAGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXY5</accession>
    <name>A0A518IXY5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">ATP synthase subunit beta</fullName>
            <ecNumber evidence="10">7.1.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">ATP synthase F1 sector subunit beta</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">F-ATPase subunit beta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10 12" type="primary">atpD</name>
        <name evidence="12" type="ORF">Mal33_39580</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:57720"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.1.2.2"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell membrane</location>
            <topology evidence="10">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the ATPase alpha/beta chains family.</text>
    </comment>
    <dbReference type="EC" id="7.1.2.2" evidence="10"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045261">
        <property type="term" value="C:proton-transporting ATP synthase complex, catalytic core F(1)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1140.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01347">
        <property type="entry name" value="ATP_synth_beta_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005722">
        <property type="entry name" value="ATP_synth_F1_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020003">
        <property type="entry name" value="ATPase_a/bsu_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004100">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036121">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024034">
        <property type="entry name" value="ATPase_F1/V1_b/a_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02874">
        <property type="entry name" value="ATP-synt_ab_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50615">
        <property type="entry name" value="SSF50615"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01039">
        <property type="entry name" value="atpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00152">
        <property type="entry name" value="ATPASE_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="4 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 10" id="KW-0139">CF(1)</keyword>
    <keyword evidence="10" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="6 10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 10" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AAA" evidence="11">
        <location>
            <begin position="152"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="160"/>
            <end position="167"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QDV57942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="484" mass="52768" checksum="DCA81A037240C2C8" modified="2019-10-16" version="1">MSTVTENKSGRVTQIIGSTFDAEFPQDALPKIYNALKITSEHKGVKVNLTGEVQQHLGGGRVRCVALGSTDGMIRGMEVIDTGSPITVPVGKGALARVFNVLGEPVDGRGPVESDERWPIHRQAPQISELSTNTELFETGIKVIDLLTPFVRGGKAGLFGGAGLGKTVILTELIARIASTHGGYSVFAGVGERTREGTDLWLEMQETEIGSTGRNVIEQTCMVFGQMNEPPGARLRVALSALTMAEYFRDTTGVDTLLFVDNIFRFSQAGSEVSALLGRMPSAVGYQPTLATEMGALQERISSTKKGAITSVQAVYVPADDPTDPAPATAFGQLDAFIYLERSISEKGIYPAIDPLASNSRILDPQYVGERHYAIARRVQTILQRYRELQDIIAILGVDELSESDKMIVHRARRIERFLSQPFLVAEKFIGKPGEVTSIGDTIRSFEEICDGKWDHLPEQAFMYVGSIEQAEEQAKQMAEKAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IY38</accession>
    <name>A0A518IY38_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_40130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022157734" evidence="1">
        <location>
            <begin position="30"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="322" mass="34717" checksum="8507D95DC2359946" modified="2019-10-16" version="1" precursor="true">MRKLHSSARMAFSLAIALAGALIDRDACAQPQFFLSAGAWVPVLPEYKAGTLLDGGSSTDLFSDDQTDAGAQLTLGGFYHFAPTRTMIESDLQIAGIGSMGSSGTFTDPGAASEGSFDSLSGSSLGVTGAGETLSMNVDSDIFHLHKYVGLRDRFSLDWIGLGDITIGCGFSWMLFDQDFQSDARFGDGRRGQYLEDLDTNYLGGEFRGTLRQSIFGQICYLDARYGIYEMDADYYGTSTYHSAAGALMDRSQLSTSLKQTTTTAELALRTDVCVGGWLVRPMIGVKYFDDMAQIERSPGGVGTSLTTDNAYIFNGSIEFSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYF9</accession>
    <name>A0A518IYF9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">MMPL family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Mal33_41310</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004869">
        <property type="entry name" value="MMPL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000731">
        <property type="entry name" value="SSD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03176">
        <property type="entry name" value="MMPL"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50156">
        <property type="entry name" value="SSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="25"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="214"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="236"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="263"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="307"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="339"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="592"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="646"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="689"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="716"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="domain" description="SSD" evidence="8">
        <location>
            <begin position="235"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="752"/>
            <end position="781"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV58114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="781" mass="84868" checksum="E8391115DD4305BF" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYX9</accession>
    <name>A0A518IYX9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ECF RNA polymerase sigma factor SigW</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">sigW_4</name>
        <name evidence="4" type="ORF">Mal33_43060</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="2">
        <location>
            <begin position="20"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="3">
        <location>
            <begin position="115"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV58288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="174" mass="19505" checksum="891B81EDA285F32C" modified="2019-10-16" version="1">MNEASSNGKPLSHATLEQAVSELLPYWLRMAQRLSGDPEIAEEAVQDALVRVAKSWKGFRGQATLQTWVGRIVIHCVRDRMTARKQPTGCQEAAPDVVAKSRGPVEELLASEQQQRVRTAIGLLPDRQREVLTLTIWEAKSVAEVGELLEISTQNVYATLHVARQRLKEILREE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZQ3</accession>
    <name>A0A518IZQ3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Vitamin B12 transporter BtuB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">btuB</name>
        <name evidence="8" type="ORF">Mal33_46000</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039426">
        <property type="entry name" value="BtuB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30069">
        <property type="entry name" value="PTHR30069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0798">TonB box</keyword>
    <feature type="domain" description="Plug" evidence="7">
        <location>
            <begin position="156"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="6">
        <location>
            <begin position="411"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="57"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="489"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="106"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="489"/>
            <end position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV58577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="810" mass="88993" checksum="5D6E0121E957B981" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZT9</accession>
    <name>A0A518IZT9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">cusS</name>
        <name evidence="9" type="ORF">Mal33_46260</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
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            <end position="249"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="257"/>
            <end position="473"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV58602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="482" mass="52927" checksum="FD7B474D45DB3A8A" modified="2019-10-16" version="1">MKLTTRVSAYFLVALAIALTIYSLVFYSVTRRQIESQFERELQGVLNSFVAVAEIEDTEVKWQPLEHSVSFGSFDDFGEIHWVVVGDKNRVVEKSRSADQAMTSLAMQLAAGNAASGTMLAQVEPKRQQRILYHRLTAPHPLAVNRELDEFDELMVVVGRSTAKRDAIVSRLTFFVTMLPLAAWCVAAGLGRWIVRHALRPVSAMADQAQAIAGSDFQTRLIVQDTGDELAELGTTFNHLLDRQQAAFEQQSRFAGDAAHELRSPITVLLGQIDVTLRRPRSVDEYRTTLELLRTKTLSLQEIVEALLFLARSEGDTASPTMQPIAFASWLNDDASTWTNLPRGADLRLENSVEQSVSVRATSTLLGRIVENLVSNAIKYSSPGSPIEVQAINDANHVVLRVTDAGCGISESDQPHLFDPFFRSSDARSKGISGNGLGLAIASRIATTLGGTLQVESTQGHGSCFTVRLPIDLNREPSNHLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZU1</accession>
    <name>A0A518IZU1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_45780</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="52" mass="5604" checksum="B1EBA32C80FF30B6" modified="2019-10-16" version="1">MCVFHVPASGLVGDSSFMTGGLCRRQFVCQPPAWLKVTACQPSTTDRLCSGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J068</accession>
    <name>A0A518J068_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Macrolide export ATP-binding/permease protein MacB</fullName>
            <ecNumber evidence="9">3.6.3.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">macB_8</name>
        <name evidence="9" type="ORF">Mal33_47620</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="3.6.3.-" evidence="9"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="281"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="324"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="367"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="8">
        <location>
            <begin position="23"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="7">
        <location>
            <begin position="309"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV58737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="405" mass="43449" checksum="565AA9DE98CD9A6E" modified="2019-10-16" version="1">MNLKKLVWRELFERKSQMITIFVGILLGITTVIAIKNITYYSEMAVAREMDSLGANILVLPKSVTLQDYYSADIHNETIPEEYALRLTMSNLAGVDNLSPKLCVPVDLEGRQFTLTGILPKSEFQAKAAWGGAGIFSRPIGCGAIDVGVAAEPEDKKTLVRNRVIDDLATDEALVGADTASVLGIEEGQTLDLMGKQFSVVAVLPETGTVDDSRIFAHLHTVQEMADKEAVVSCIEIVGCCKEISAGLVDNVNKLLPEAKVVTVTQVVATQTKVNGMMEQLSMIFVAIIVVIGGAGIANFMFANVYERRREIGTLMSLGAESHLILRIFLLKALLLGFAGGVGGFLIGTALAVTLGPRLANVPVLPMPVLALWAIGISVGTTLLASYFPARNAARLDPVTSFQEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0K7</accession>
    <name>A0A518J0K7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_48940</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="59" mass="6685" checksum="8FD99962AFC8A44A" modified="2019-10-16" version="1">MTSLTAPRKQRPQFSSLVDSARERIASNWNAQERAQRKAEAERKLASLCQMLLSPQKVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0M3</accession>
    <name>A0A518J0M3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">pknB_22</name>
        <name evidence="10" type="ORF">Mal33_49070</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001440">
        <property type="entry name" value="TPR_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="80"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="7">
        <location>
            <begin position="641"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="7">
        <location>
            <begin position="675"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="7">
        <location>
            <begin position="709"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV58882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="793" mass="87341" checksum="997D041040BF57DC" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J140</accession>
    <name>A0A518J140_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_50750</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="139" mass="15562" checksum="85FBCF6F948ADC4D" modified="2019-10-16" version="1">MLDLNHPDTPITFAVAAEHGKVLHYAKRMTLVSTQDRQRLLDEALNACAAIRDITKQRWGNAKNKIKSVELLETNLRELASTQSTNDYADSWEGCNCDVCDSPIEDLPGYPDMVYCRTCIAAVRPGLDAVDRSYGLWCI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1C1</accession>
    <name>A0A518J1C1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_51620</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021870653" evidence="2">
        <location>
            <begin position="22"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV59136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="121" mass="13000" checksum="1EF97B7F7F0DF4A8" modified="2019-10-16" version="1" precursor="true">MRFWKFAPVLLGGLLIPVIYGCSSTEPDQVTPTATPASDTADDHADAKSPMDKMMPGLKELSPQDYKSAMAQHICPVSGEMLGTMGAPKKVDVDGEAIWICCDGCKAKLLAEPDKYLAKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1H2</accession>
    <name>A0A518J1H2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin)</fullName>
            <ecNumber evidence="4">1.17.7.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4 5" type="primary">ispG</name>
        <name evidence="5" type="ORF">Mal33_52110</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>(2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + H2O + oxidized [flavodoxin] = 2-C-methyl-D-erythritol 2,4-cyclic diphosphate + reduced [flavodoxin]</text>
            <dbReference type="Rhea" id="RHEA:43604"/>
            <dbReference type="Rhea" id="RHEA-COMP:10622"/>
            <dbReference type="Rhea" id="RHEA-COMP:10623"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57618"/>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <dbReference type="ChEBI" id="CHEBI:58483"/>
            <dbReference type="ChEBI" id="CHEBI:128753"/>
            <dbReference type="EC" id="1.17.7.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="4">Binds 1 [4Fe-4S] cluster.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 5/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the IspG family.</text>
    </comment>
    <dbReference type="EC" id="1.17.7.3" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00056">
        <property type="reaction ID" value="UER00096"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046429">
        <property type="term" value="F:4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019288">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.413.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00159">
        <property type="entry name" value="IspG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011005">
        <property type="entry name" value="Dihydropteroate_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016425">
        <property type="entry name" value="IspG_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004588">
        <property type="entry name" value="IspG_bac-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045854">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30454">
        <property type="entry name" value="PTHR30454"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04551">
        <property type="entry name" value="GcpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004640">
        <property type="entry name" value="IspG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51717">
        <property type="entry name" value="SSF51717"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00612">
        <property type="entry name" value="ispG_gcpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3 4" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 4 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="4">
        <location>
            <position position="286"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="289"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="323"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="330"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV59183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="380" mass="41722" checksum="E56AC49829B1B09D" modified="2019-10-16" version="1">MTIQRNPTRRVQIGSVVVGDGNRIAVQSMTATKTQNVEATAAQANALHAAGADVVRIAVDSEKDVAALAEIRKLTEANLAVDLQENFRLAELVAPHVDKIRYNPGHLYHHQKDKPWQEKVEFIINQAKRHDCAIRIGVNCGSVDPEKANKFDPEDSITPMLESAWEHCEFVDSLGFDRYVVSLKDSDPDKVVEVNRRFAEKRPDVPLHLGVTEAGMPPDGIIKTRIAFEQLIGHGIGDTVRVSLTVPNDRKHEEIEAGRGIVDDIASGRVRSVVVFDRNSLNIISCPSCSRVENEAFVDLAAKVKEMTAYAKEHAITIAVMGCRVNGPGETDDADLGLWCGPNHVNLKRGPEALGAYKYDEILPVLKQELDQLIAANHAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1U2</accession>
    <name>A0A518J1U2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ECF RNA polymerase sigma factor SigE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">sigE_7</name>
        <name evidence="4" type="ORF">Mal33_53350</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="2">
        <location>
            <begin position="34"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="3">
        <location>
            <begin position="123"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV59307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="187" mass="21582" checksum="32B5BAA43A2AC13A" modified="2019-10-16" version="1">MSEPDPISEQVRECADRIAESGAAALSGLYDLTSGRLVRFATTVTRNQHDAEDAVQSALVKVADNPRTLRRAERPWPYLLQMVRNESLLILRRKKRWRFATGIFDLLTRCPVDELEQEETYRMVWSAMRRLPPKQSEVVALKIWENFTFAQIGEVLMISPATAASRYRYGIAKLEIELRGEEVEERR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J293</accession>
    <name>A0A518J293_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Vibriobactin utilization protein ViuB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">viuB</name>
        <name evidence="2" type="ORF">Mal33_54860</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
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        <property type="entry name" value="SIP_C"/>
    </dbReference>
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        <property type="entry name" value="SIP_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30157">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04954">
        <property type="entry name" value="SIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="1">
        <location>
            <begin position="4"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="251" mass="27949" checksum="B26DD13F408D4B69" modified="2019-10-16" version="1">MAKPTPIELEVIRTTSLTEHMLRVTLGGDALASFPEEQESAYIKLIFPQGEGKRPVLRTYTIRHQRPTEIDVDFALHDAKGPALTWAVNAQPGDRILVGGPGPKKLIQHDADWFLLAGDMSALPAISVNLSKLPADAVGYAVIEVLSEADIQSLDHPEKMELRWEINPHPDPNGEFLPSKIEALPWLEGTPAVWAACEFNSMRNLRRLLKQRADLPNSHLYLSSYWKIGQTEDEHKVAKRNDSEHDAAAVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J2A3</accession>
    <name>A0A518J2A3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Thiol:disulfide interchange protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_54960</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
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        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="28"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="4">
        <location>
            <begin position="39"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV59461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="170" mass="18960" checksum="685D7AA814F8FA6B" modified="2019-10-16" version="1">MTTDDSVSNASSLTAAPTSAPRKRFFHFWRCFWLAFLVISLGYAWYCFYVPTNRVAWADDFDTAQQQAVAEGKPMVLFFTSQWCVPCRTMKRNVWADDQVSAVVNESLIPVTIDVHDPQAAATIDQYRVKATPVTVVTDSQGNPLQWKQGGISKADFLELLVAAKPSTDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J2D3</accession>
    <name>A0A518J2D3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_55260</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022131586" evidence="3">
        <location>
            <begin position="23"/>
            <end position="1034"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1013"/>
            <end position="1034"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="412"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV59491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1034" mass="113627" checksum="60806B904BB667B9" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J2F9</accession>
    <name>A0A518J2F9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Linear gramicidin dehydrogenase LgrE</fullName>
            <ecNumber evidence="3">1.1.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">lgrE</name>
        <name evidence="3" type="ORF">Mal33_55610</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the thioesterase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.-.-" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012223">
        <property type="entry name" value="TEII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001031">
        <property type="entry name" value="Thioesterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11487">
        <property type="entry name" value="PTHR11487"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00975">
        <property type="entry name" value="Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioesterase" evidence="2">
        <location>
            <begin position="15"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV59526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="244" mass="27036" checksum="16C90F9C7139F77D" modified="2019-10-16" version="1">MFRTIYEAAEPKLQFFWFCHAGAGSASLVRAARGLSGPLSLQVASLPGREHRFRDGLNLSLDELVDQLAAELRAQIRGPYHLIGHSFGSLLSYLLAQKMIAAGLPPLSLTVMTLAAPDRVNRNPRTAHLTNEEFLDYLDHRFGSVPRALRTNPEAAALFLPIVRYDLQLLESYVHQPTPPLPIPILALAGSEDRAVSPEAMRQWERFTSESFELQTIPGGHFFPTENVDPIIQRAIGSFQQGPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IM62</accession>
    <name>A0A518IM62_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycerophosphoryl diester phosphodiesterase</fullName>
            <ecNumber evidence="3">3.1.4.46</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ugpQ_1</name>
        <name evidence="3" type="ORF">Mal33_01280</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.4.46" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008889">
        <property type="term" value="F:glycerophosphodiester phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030395">
        <property type="entry name" value="GP_PDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03009">
        <property type="entry name" value="GDPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="SSF51695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51704">
        <property type="entry name" value="GP_PDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022118033" evidence="1">
        <location>
            <begin position="20"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="domain" description="GP-PDE" evidence="2">
        <location>
            <begin position="30"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="273" mass="30389" checksum="8BD16C203C607CF6" modified="2019-10-16" version="1" precursor="true">MTATQFLSVLLLAFGQVFFAVDATDEFLANGVTAHRGNSGDFPENTLSAFKSGMEVGADWIELDIFRTKDGRLVVTHDKTTERVGDKNVRVPDSTYEELLAVDVATAFRRRSGNTVEECPAQCIPLLEDVLRLVMKQNRTRVSIQPKMDCVAEAVELVKELKAERWVGFNDGNLQFMTEVKQLAPEIPVFWDRGAGTNIDDDIRIAKQHGFESLVLQYSGITPEKVQKIKAAGLEAGAWTVNDQSMMSKLLDIGVQRIYTDHPSALLALKREL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IN75</accession>
    <name>A0A518IN75_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tRNA pseudouridine synthase D</fullName>
            <ecNumber evidence="4">5.4.99.27</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">tRNA pseudouridine(13) synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">tRNA pseudouridylate synthase D</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">tRNA-uridine isomerase D</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4 6" type="primary">truD</name>
        <name evidence="6" type="ORF">Mal33_04940</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>uridine(13) in tRNA = pseudouridine(13) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:42540"/>
            <dbReference type="Rhea" id="RHEA-COMP:10105"/>
            <dbReference type="Rhea" id="RHEA-COMP:10106"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="EC" id="5.4.99.27"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the pseudouridine synthase TruD family.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.27" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106029">
        <property type="term" value="F:tRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031119">
        <property type="term" value="P:tRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2340.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2350.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01082">
        <property type="entry name" value="TruD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001656">
        <property type="entry name" value="PsdUridine_synth_TruD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020119">
        <property type="entry name" value="PsdUridine_synth_TruD_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011760">
        <property type="entry name" value="PsdUridine_synth_TruD_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042214">
        <property type="entry name" value="TruD_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043165">
        <property type="entry name" value="TruD_insert_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01142">
        <property type="entry name" value="TruD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50984">
        <property type="entry name" value="TRUD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01268">
        <property type="entry name" value="UPF0024"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="TRUD" evidence="5">
        <location>
            <begin position="155"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV54539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="340" mass="38512" checksum="CC4DD0BBE7EFD013" modified="2019-10-16" version="1">MNPIDPPRLLGPSLGSVIFKSQPEDFEVEELLRFEPSGEGEHCLVWLEKRHRNTNDVASELATKLGLRKRLISHCGLKDKEAVTRQWFSLHLPGKPSPSAEDLTVEGVRVLRIVRHLRKLHRGAHDGNRFWIRLRGCEFSREAAAARWQQMIDRGVPNYFGTQRFGRDGGNVPQALRWFKDEIQVRDRMLRGILLSAARSYLFNACVGHRVLDGTWDTPLSGDVFGFADNRSLVLPHNLHGDEADRVRQGALELTAPLWGEGELQSQAAVKAMEEQVVAAYPDLLAGLAQFNLRQERRVMRLRPLSAELTWESDSTLVLRFDLPKGTYATTLLRELVDIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INA3</accession>
    <name>A0A518INA3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein-tyrosine-phosphatase</fullName>
            <ecNumber evidence="3">3.1.3.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ywqE</name>
        <name evidence="4" type="ORF">Mal33_05120</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10684"/>
            <dbReference type="Rhea" id="RHEA-COMP:10136"/>
            <dbReference type="Rhea" id="RHEA-COMP:10137"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:82620"/>
            <dbReference type="EC" id="3.1.3.48"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.48" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016667">
        <property type="entry name" value="Caps_polysacc_synth_CpsB/CapC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016195">
        <property type="entry name" value="Pol/histidinol_Pase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39181">
        <property type="entry name" value="PTHR39181"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19567">
        <property type="entry name" value="CpsB_CapC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016557">
        <property type="entry name" value="Caps_synth_CpsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89550">
        <property type="entry name" value="SSF89550"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV54557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="265" mass="29548" checksum="6B8EC4DBCACD4A1E" modified="2019-10-16" version="1">MDEELAFIDIHCHLLPGIDDGARDWDESLAMARIAVQDGIRCSVLTPHQLGQYSLTTGDEIRRLTAEFQTRLQEQEIPLVVRPGADVRIDLDMIERLASGDCVSLSDRSKHVLLELPHELYFPLEPVLANLKKLGMVGILSHPERNEGILKRPELIPPLVQAGCLMQITADSLTGVFGSAPKKMSEWLLQNGLTHFIASDAHGTRRRKPLMRRSFDRASELVGEAYATAICCHNPLAVVNGKTVAKLPPIKRRGWMDRILKRQAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INC9</accession>
    <name>A0A518INC9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tetratricopeptide repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_05420</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001440">
        <property type="entry name" value="TPR_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="60"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="414"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="465" mass="52221" checksum="646FDE8EE1F0D666" modified="2019-10-16" version="1">MKRLKQLLIVILVLEVIFCGIYVKRRLWNHHVVLPAVTLDDPLLAAEFQQLADQAATGGSAEWQALGEGLLGQGFYGEAEHAFRAAVDIDPSNYMAHFALAFCLDRTGRIAESSEEYLKAAEIQRKSKQLVGSVEHCLYQVGKNHLREEDAAAAIDSFASQAGFAPASYQYAKLLVRDGKVDRAMPVLKMELDKTPLSLKFNALRLQALESTGQQRLADEAADVLQRSQYQIPIDLNTDYVTPMNQRLGISRQLQEYNELLASGDMDLLAKHLQSMWEVVEPTTLNQKSKILISMAEVAFQRRRAEEMLHAVDRLKELGVSSPDMLQLEGAAYQLNGDIDRAIALWIRASEMSPNIPLHQILADAYQQKNDDARRDYHRGQAALLEAKLAYWNNQWEPAKQAAQRAIDVDPSLDQAWFYLAEIERELGNPQPALEAYQKCLELNPNHGRALAAESRLGEKEVDSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INF0</accession>
    <name>A0A518INF0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_05660</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010330">
        <property type="entry name" value="CoiA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06054">
        <property type="entry name" value="CoiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="279" mass="32469" checksum="73D43128F37AC8CD" modified="2019-10-16" version="1">MQLALVNNERSEAFPGGRGICPVCSSEVIAKCGPRVMHHWSHLRLRDCDPWWENETDWHREWKNLFPIECREVSHTADDGEIHRADIKTLTGIVIEVQHSSMTDAERISREQFYKNLVWVVDGSGFKKNFDIYHLLPKPDSELAADIVWVKAKRQLDGANRGMFFRVSEARKENPAASKENIRGGYYHFMDEIEDEVNRSYTGYHQFDWVRPRKTWLDASCPVYIDFGDDNLVKLETYDESGLKCIRFVHKRKFVHDAMVESQATDIATRFYPLPDVAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ING6</accession>
    <name>A0A518ING6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptide chain release factor 1</fullName>
            <shortName evidence="5">RF-1</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">prfA_1</name>
        <name evidence="5" type="synonym">prfA</name>
        <name evidence="7" type="ORF">Mal33_05820</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 5">Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="5">Methylated by PrmC. Methylation increases the termination efficiency of RF1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the prokaryotic/mitochondrial release factor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016149">
        <property type="term" value="F:translation release factor activity, codon specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00093">
        <property type="entry name" value="Rel_fac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005139">
        <property type="entry name" value="PCRF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000352">
        <property type="entry name" value="Pep_chain_release_fac_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045853">
        <property type="entry name" value="Pep_chain_release_fac_I_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004373">
        <property type="entry name" value="RF-1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03462">
        <property type="entry name" value="PCRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00472">
        <property type="entry name" value="RF-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00937">
        <property type="entry name" value="PCRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75620">
        <property type="entry name" value="SSF75620"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00019">
        <property type="entry name" value="prfA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0488">Methylation</keyword>
    <keyword evidence="4 5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCRF" evidence="6">
        <location>
            <begin position="66"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="modified residue" description="N5-methylglutamine" evidence="5">
        <location>
            <position position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV54627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="360" mass="40981" checksum="D5A4A3F3DFD086AF" modified="2019-10-16" version="1">MTSIRDTLDEKLKRFLDLERQMSDPAVQSDGTLMSAVAREHGGLAKMANKFRTFKKLTDEIRGCKEIIEETDDPDEREMAEEEADSLRKKREALWDELLTMTVGGEDSHRTRCVMEIRSGTGGDEAALFARDLFEMYRKHAERVGWKTEILDSSATELGGFKEITLAFEGESVFRDLQYESGGHRVQRVPETETQGRVHTSAATVAVMPEPEDVEVTLKSEDYRIDKFCASGPGGQHVNKTESAIRLTHHDTGIVVQCQDEKSQHKNLAKALRVLKTRIYEQKREEELAKRADTRKSLIGSGDRSQRIRTYNFPQNRLSDHRINLTLYKLDQIIAGDLQPVTDAMIEYDRDQLRGDMGEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INI0</accession>
    <name>A0A518INI0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_06080</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="78" mass="8452" checksum="00FDCEC6D024FD11" modified="2019-10-16" version="1">MTDSSPDAVSFNRVPHGPRVLQTDARGVATAVKRFVQAELLSAETATYLRSISFFMSSVIGMTSKSLKYISQSVPPCI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INJ5</accession>
    <name>A0A518INJ5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD dependent epimerase/dehydratase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_06130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="46"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="341" mass="37137" checksum="B263FF05DDEE6CE9" modified="2019-10-16" version="1">MPDLIESEAQLDAMLAQPDDRLIDFMRQLEGDLIILGIAGKMGVSLGQLAVAAIEKAGVEKNVYGVARFSDADARGRLEAAGVRTIQCDLLDRTAVAKLPQSPNVLFMAGRKFGTGGEEPLTWAMNTLVPANVADHFRDSRIVAFSTGCVYPLARVDSQPDETTPPDPIGEYAQSCLGRERMFEYGSNRWGTPVCLYRLNYSIDLRYGVLHDIATKIWHGQPVDNSAEAFNVIWQGDANRQALLCLGHCSSPASILNVTGPETLETEAVARQFGELLEKPVQFTSTPGDGCYLSDSSQATKLFGSPSVTADQLIRWQAHWIKTGGRSLGKPTHFEISDGAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INX6</accession>
    <name>A0A518INX6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nucleoside transporter YegT</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">yegT</name>
        <name evidence="2" type="ORF">Mal33_07590</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005337">
        <property type="term" value="F:nucleoside transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004740">
        <property type="entry name" value="Nuc_H_symport"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03825">
        <property type="entry name" value="Nuc_H_symport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="104"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="140"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="166"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="213"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="253"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="277"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="303"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="339"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="434"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="470" mass="51462" checksum="AEBB8AA2CCDFA7D0" modified="2019-10-16" version="1">MSTAAPTSQSNMTTRLSIMMFLQFFAWGAWFATLALALGSNGLAEFTGGAYESAPIAAIFAPLFLGLIADRFFASERVMGVLLLIGGGIMCMLPSIAADGDGTLMVRLMIAYMCCYMPTLGLSNTIAFTHIPDQNHFPKIRVWGTIGWIVAGLTLGFAGWSDSLNIFWLGAISSILLGLYSFTLPHTPPPAKDTPLDFRSLLMLDAFGMMKSPGFLVFAICSMLICIPLGYYYGQTSAYLGAAGFTEPGSTMTLGQMSEIFFMILIPFFFRKLGVKLMLMIGMASWVLRYLLFAMGAPDQVTWMLLLGVALHGICYDFFFVTGFMYTDNKAPREIRGQAQSLLVFLTQGLGLFFGFRFAFGANFPFTNIPLPTRIGEYGAAPGPELAEQISALRADAATPTFLESLMNMFNKGYPEGLDTAAYVVPAMQDWKNYWIFPAILASAVFVLFTVGFWDRMTPAAEEEATTEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP14</accession>
    <name>A0A518IP14_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_07730</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025841">
        <property type="entry name" value="CP_ATPgrasp_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016450">
        <property type="entry name" value="UCP005522"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14403">
        <property type="entry name" value="CP_ATPgrasp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005522">
        <property type="entry name" value="UCP005522"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="465"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="465"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="504" mass="55769" checksum="8EB9688150EEDAD5" modified="2019-10-16" version="1">MINASENYSSGGAFDEMFTPNGEARGYCAPYVNKLGKLQAGELGRRQTSAEHALRNMGITFNVYGHADGREKVWPFDVLPRIIDGNEWNQVEAGLKQRIRALNLFLDDIYNEQDILHDKILPEDLLATAGTLRPQMRGFSPAKRVWCHITGVDLVRDADGTIYVLEDNLRCPSGVSYVLENREVMKRTFPQVFEGIAVRPVEEYSEQLLKTLLQCAPPGTIAPTAVVLTPGSYNSAYYEHTFLAQQMGVQLVQGSDLVVENGYVHMRTTQGLQRVDVIYRRIDDDFLDPKCFRKDSCLGVPGLIDVYRAGRVTLANAPGTGVADDKAVYAYVPEIIKYYLDEDAILQNVPTYVCADPKHRQHVLANLDKLVVKPTNESGGYGILMGPQSTREEQAKYVDLINANPRNYIAQPMLNLSTVPTLVDDRLQPRHVDLRPFVLCGEDIYVMPGGLTRVALTEGSMIVNSSQGGGSKDTWVMDNSTSQPAPPAPAPEPESGQSQSQSQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP20</accession>
    <name>A0A518IP20_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">CNNM transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Mal33_08060</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002550">
        <property type="entry name" value="CNNM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01595">
        <property type="entry name" value="DUF21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51846">
        <property type="entry name" value="CNNM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="67"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="91"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="130"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="CNNM transmembrane" evidence="7">
        <location>
            <begin position="1"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV54841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="319" mass="35257" checksum="5EB25A628B5F1966" modified="2019-10-16" version="1">MIFFLLLFAFGISLSAFFSGSETGLYRVPRVRLVLDAISGRLVSKVLLWLANHPTVFVATVLVGNNIANYLTSFAVVMAISLVISNNQSAAELFGTVMVTPIVFVFGELLPKYLFFNAPYRMLGFSGPLLVLTTILFLPITGLLVLLNNLLSAFSGPAPFQSRQSMARGELQQMLRHGHTIGLLKPSQQRTAQNMWQVGERPAKAFAVPPDRLARIPSTATPDEAITAARRQGHPLILVEDPKTRRTTGYVRYADLASAELPLVNRIRPVVRVKQEANNLQVLFELYDKHSDIAELIDAAGQVTALVTLRQLQEPLLRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP63</accession>
    <name>A0A518IP63_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Thermophilic serine proteinase</fullName>
            <ecNumber evidence="10">3.4.21.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Mal33_08410</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the peptidase S8 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.-" evidence="10"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07473">
        <property type="entry name" value="Peptidases_S8_Subtilisin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034204">
        <property type="entry name" value="PfSUB1-like_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003368">
        <property type="entry name" value="POMP_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01376">
        <property type="entry name" value="POMP_repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="4 8 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 8" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0720">Serine protease</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Peptidase_S8" evidence="9">
        <location>
            <begin position="218"/>
            <end position="542"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV54876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1116" mass="116431" checksum="571FC0398C0825CA" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP65</accession>
    <name>A0A518IP65_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_08190</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010390">
        <property type="entry name" value="DUF990"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06182">
        <property type="entry name" value="ABC2_membrane_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="117"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="147"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="180"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="237"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="267" mass="30213" checksum="B89ABE6E6D06C0E6" modified="2019-10-16" version="1">MIVRISLEERLVYRGDFALGTLMRFLPIITQIFLWSAVFASMAQPGEETTFGGFRFHDMVAYYLITMVARAFSSMPGLSSGIARQIRDGEIKKFMIQPIDLLGFLLLGRVAHKVAYYSVATLPFVLVFFLCRSYFVDGWPDPTIIAAFAATLVMGFLIGFFLEAAIGLIGFWFLEVSSLLFIYMLFSFFLSGHMFPITLLPDEIEWFVQLLPLKYLAYFPAAVFLGKIPPDELGQELLIEAGWVVFLIIVCRVMYARGVRRYSGFGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP73</accession>
    <name>A0A518IP73_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HicB family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_08520</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013321">
        <property type="entry name" value="Arc_rbn_hlx_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010985">
        <property type="entry name" value="Ribbon_hlx_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035069">
        <property type="entry name" value="TTHA1013/TTHA0281-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008651">
        <property type="entry name" value="Uncharacterised_HicB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05534">
        <property type="entry name" value="HicB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143100">
        <property type="entry name" value="SSF143100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47598">
        <property type="entry name" value="SSF47598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="133" mass="14649" checksum="F387DEECCDE692C3" modified="2019-10-16" version="1">MIEYKGYVGKVEFDDEAAIFHGEILGTRDVITFQGESVSELTQAFRDSIDDYLAFCKERGESPDKPFSGQFVTRIPHELHRQVSMAANVAGKSLNAFVKEQLEAAVEKVAAKPKRGGTTKVNTKAKPRGKQSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPF1</accession>
    <name>A0A518IPF1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Serine--tRNA ligase</fullName>
            <ecNumber evidence="7">6.1.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Seryl-tRNA synthetase</fullName>
            <shortName evidence="7">SerRS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Seryl-tRNA(Ser/Sec) synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 10" type="primary">serS</name>
        <name evidence="10" type="ORF">Mal33_09440</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>ATP + L-serine + tRNA(Sec) = AMP + diphosphate + H(+) + L-seryl-tRNA(Sec)</text>
            <dbReference type="Rhea" id="RHEA:42580"/>
            <dbReference type="Rhea" id="RHEA-COMP:9742"/>
            <dbReference type="Rhea" id="RHEA-COMP:10128"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78533"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.11"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + L-serine + tRNA(Ser) = AMP + diphosphate + H(+) + L-seryl-tRNA(Ser)</text>
            <dbReference type="Rhea" id="RHEA:12292"/>
            <dbReference type="Rhea" id="RHEA-COMP:9669"/>
            <dbReference type="Rhea" id="RHEA-COMP:9703"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78533"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.11"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Aminoacyl-tRNA biosynthesis; selenocysteinyl-tRNA(Sec) biosynthesis; L-seryl-tRNA(Sec) from L-serine and tRNA(Sec): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer. The tRNA molecule binds across the dimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="7">Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.11" evidence="7"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00906">
        <property type="reaction ID" value="UER00895"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004828">
        <property type="term" value="F:serine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016260">
        <property type="term" value="P:selenocysteine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097056">
        <property type="term" value="P:selenocysteinyl-tRNA(Sec) biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006434">
        <property type="term" value="P:seryl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00770">
        <property type="entry name" value="SerRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00176">
        <property type="entry name" value="Ser_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002317">
        <property type="entry name" value="Ser-tRNA-ligase_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015866">
        <property type="entry name" value="Ser-tRNA-synth_1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042103">
        <property type="entry name" value="SerRS_1_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033729">
        <property type="entry name" value="SerRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010978">
        <property type="entry name" value="tRNA-bd_arm"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11778">
        <property type="entry name" value="PTHR11778"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02403">
        <property type="entry name" value="Seryl_tRNA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001529">
        <property type="entry name" value="Ser-tRNA-synth_IIa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00981">
        <property type="entry name" value="TRNASYNTHSER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46589">
        <property type="entry name" value="SSF46589"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00414">
        <property type="entry name" value="serS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 7 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="9">
        <location>
            <begin position="137"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Serine binding" evidence="7">
        <location>
            <begin position="229"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="44"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="260"/>
            <end position="262"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="276"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="283"/>
        </location>
        <ligand>
            <name>L-serine</name>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="350"/>
            <end position="353"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="386"/>
        </location>
        <ligand>
            <name>L-serine</name>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV54976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="424" mass="46890" checksum="3B6A3905CFE8A553" modified="2019-10-16" version="1">MLDRKFIVEHADQVQANCERRGVSCEVQRIVSLEAQRKTLLTDSQEFNRLANEVSKKIKSAKDNDERQQFIAEGRDLRQKKDAAQKQHDEIDAEVLSLISAIPNMTHPDVPSGGEEDAKEVGFGKTAVRTFDFAVKDHLELAQPLDLVDFEAGARVTGSGFYFLKNDAVLLDLALQQFAIRHLMSKGFIPVTTPDLATTSVLQGIGFTPRGPETQIYSIENSDLHLVGTAEITLGGMYADQTVDLEELPIKLCGLSHCFRTEAGAAGRASRGLYRVHQFTKVEMFAFTSPEQSDAMHEELRQTECELFDALEVPYRIVDTASGDLGGPAYRKYDLEAWMPGRGEAGEWGEVTSTSNCTDYQARRLNVRYKTKGEKGTNFVHTLNGTAFATGRAMIAIIENNQQADGSIAVPKALQPWVGKEKIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPH0</accession>
    <name>A0A518IPH0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ATP-dependent Clp protease adapter protein ClpS</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1 4" type="primary">clpS</name>
        <name evidence="4" type="ORF">Mal33_09420</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Binds to the N-terminal domain of the chaperone ClpA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ClpS family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030163">
        <property type="term" value="P:protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00302">
        <property type="entry name" value="ClpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022935">
        <property type="entry name" value="ClpS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003769">
        <property type="entry name" value="ClpS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014719">
        <property type="entry name" value="Ribosomal_L7/12_C/ClpS-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02617">
        <property type="entry name" value="ClpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54736">
        <property type="entry name" value="SSF54736"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ClpS" evidence="3">
        <location>
            <begin position="23"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV54974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="114" mass="13015" checksum="88D88EBD356AA32A" modified="2019-10-16" version="1">MTSKSAAAAIPEVEQQGTRPKPKRQPRYNVILWNDDDHSYEYVMMMMKELFRYPIEKGFQVAKEVDRSGRAICLTTTREHAELKRDQIHAFGKDSLIARCQGSMSATIEPVPGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPR2</accession>
    <name>A0A518IPR2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">BNR/Asp-box repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_10310</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011040">
        <property type="entry name" value="Sialidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036278">
        <property type="entry name" value="Sialidase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13088">
        <property type="entry name" value="BNR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50939">
        <property type="entry name" value="SSF50939"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021851808" evidence="1">
        <location>
            <begin position="32"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="domain" description="Sialidase" evidence="2">
        <location>
            <begin position="69"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="534" mass="58209" checksum="654AD91341623F64" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPZ7</accession>
    <name>A0A518IPZ7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Mal33_11090</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the HisA/HisF family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00412"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006062">
        <property type="entry name" value="His_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00977">
        <property type="entry name" value="His_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3 5" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV55140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="254" mass="26267" checksum="4C0CE572AE21A678" modified="2019-10-16" version="1">MLSTTAEPTDDDPLASVLGVIDLKGGKAVHAVRGNRDSYRPVCCAATNDGDPIALAQMYLDSGVGGLYVADLDAITAGAPHDDLLNRLADLGAPIWIDAGVVDLQLAASDRIVRVVGTESIASLEELVPLRERWSARRHGIVLSIDLREGVVLGGSPALASQTAVEIASEAIGSGFRRLITLDLAAVGAASGTLTLPICQAIAEKHPHVELTSGGGIRTLADIYVLKEGGCRYVLVGTALHGGRKKLSFGGGTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQD4</accession>
    <name>A0A518IQD4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_12820</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010390">
        <property type="entry name" value="DUF990"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06182">
        <property type="entry name" value="ABC2_membrane_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="133"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="164"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="223"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="258"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="291" mass="33186" checksum="5EA8AEB9F32DFD58" modified="2019-10-16" version="1">MKSTMAEPNQGPHYGRVLLTFARNSLVRDMTFRANFLFQCISSVSWTLMNVGFYLIIFQYTNSIGEGTGWHKHQFFLFLATTWFINSLVQAFFMPNAEEFSELIRTGGLDFALLKPIDTQFLVSFHKVDWSSLSNFAVGLVLAAISLSYLITDPVAPLQITATMVILYPLFILCGVAIMYSLMISLSATSIWLGRNQTLYNFWFYITNFSRYPMEIYQNGWGWSLWGLFTFVIPVLVVVNVPARIIAKPLDPRAAWEWPLAGFMLFATVVCLVASRWVFRKALLSYRSASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQK9</accession>
    <name>A0A518IQK9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cadmium, cobalt and zinc/H(+)-K(+) antiporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">czcD_1</name>
        <name evidence="6" type="ORF">Mal33_13450</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1510.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002524">
        <property type="entry name" value="Cation_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027469">
        <property type="entry name" value="Cation_efflux_TMD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01545">
        <property type="entry name" value="Cation_efflux"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161111">
        <property type="entry name" value="SSF161111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01297">
        <property type="entry name" value="CDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="52"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="82"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="106"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="140"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="168"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV55374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="200" mass="20654" checksum="3CFC8DFAFF419932" modified="2019-10-16" version="1">MTDCGCELEAEGDAQRRTLRVVLAINAAMFVVEIIAGVLASSTGLIADSLDMLADASVYAISLYAVGRAANIRRNAATASGVLQLALGFGVLIEAVRRFIGGGEPIGVAMMAMGFIALIANSFCLWLIAKHKGGDVNFRASYIFSANDVIANIGVIVSGLIVKLSGSQIPDLVIGILIASVVVRGGIKILRMAGSGEEAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQW7</accession>
    <name>A0A518IQW7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_14720</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="258" mass="30511" checksum="2F7166F29810EF76" modified="2019-10-16" version="1">MFANRWRLRNKSVSNPSNPHLYIHHHLGLGDMIHCNGMVRALLAQLPEEQNVRVFCKQSYSSMVEWMYRDQPRIELRCIDQKKRETPEVRRVLRAERATNFLSVGHKAMRPLEAAHPELFFDQLFYLQLGMPYENRFSQCYWQRDLEEEERVFRKLAPEGEYAFVHDDPSRGFQLKTEHIDIPIVRNDVTESIFHMGLLLERAKEIHCMESSIRCMIESLDVENVQLYWHAFRYGSRALGTATCKNWVTVPYHLAEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQX9</accession>
    <name>A0A518IQX9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">D-inositol-3-phosphate glycosyltransferase</fullName>
            <ecNumber evidence="2">2.4.1.250</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">mshA_3</name>
        <name evidence="2" type="ORF">Mal33_14740</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.4.1.250" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102710">
        <property type="term" value="F:D-inositol-3-phosphate glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="204"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="413" mass="45852" checksum="8542DA1926E29647" modified="2019-10-16" version="1">MRVLIFEPQHAGHNLAYVSRLCEGVQTLGCEVHLATSRQAAASEQFEQHLGARRNLRVLPLDGFHQRAGSGVIRVNGPKGVRSLHRGFWNALQEVKPDHVFVPFGNPISNWYGLPNRVSRYLKANQIETELVLLFGRYAYPLDGLRSRCKQRYALSMLQRGPWTKIHHILPHAVRVISSFSRQLQAKTNYLPDPVDPLPSIDRQQARQLIGVPADGRYITMMGLIEERKGVHQLLAAFRTALPNLQPNDRVLLAGKASEDVRLALSENYADLVASQRIIALDRHLDGQAFGASCCASNLICTPYPRHQYSASIVIQAAAAGLPVLGNAVGWIDETIRTYQLGTTCDTNDPACFAKQLSIAVNTSDDFTPAADIDQFVQRHSVDNFKTLLTARLRERLGVEAGNDSLLERRAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQZ1</accession>
    <name>A0A518IQZ1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_14800</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007657">
        <property type="entry name" value="Glycosyltransferase_61"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04577">
        <property type="entry name" value="Glyco_transf_61"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV55504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="397" mass="44178" checksum="BBB52516AA3B76D1" modified="2019-10-16" version="1">MDIAQHNRKLVHYGKYVFALSTLLPFRRGNKKPTERLSTAELLARYPERVKMLWREKAGSLPAKSPHDAVESDRTGDFDDGLVMEIEGGWCHGRQCDWIGIDNVVLSELHRCDGPLAPKAVPGGWLNPRRIRRAVTTPRRLPQPVHVAGDVVVLNTSGSHNYFHWLCEVLPRLELVREAGVLQADAYVVDNYKPFHRQALELLGIPAAKVIEPHEGLLIQADRLIVPSLATAVSRRRLGARLQSRLGPATGVSQPPSQRRLYVSRRLARNRSLGNDAEVAALLASHGFESHCLEQYTLAEQVRLFRDAAVVVGLHGAGLTNILLSPNPIDLIEIKPSNCDRDYFELLANEVGATYQQVSASRNRWRGPWHCPLEPLENAVRDAIAASESELLAPHTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IR64</accession>
    <name>A0A518IR64_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_15470</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="263" mass="29296" checksum="3B13C65A7D0075E0" modified="2019-10-16" version="1">MDDSADRNGSISLNRSGAALNKLKQPNGTHSMKSVFRKTCKLLTIAALLSHTGLAASSIQAEELPVVFQDDFENGVQRWQPTDAAKWKVTKQADGSNAYHLLGKSDYQPPHRSPHSISLIKDLVVGDFELTARVQTLQTSRGHRDMCIFFGYQDPANFYYVHLGQETDPHANQIFIVNDAPRVAISESTNAGTPWKDGTWHQVKVVRRVADGLIEIYFDDMDKPQMVTHNREFQFGQIGLGSFDDLGLWDDVVVRGIPAKASK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IR65</accession>
    <name>A0A518IR65_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HEAT repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_15560</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="230" mass="25358" checksum="A2A5E15CC664E914" modified="2019-10-16" version="1">MHRLTPLAILTTCALLAGCHDGPLFALKTINPVYRSQWADDEKLGPTDAQRHEELQRLVASMPSLSDADQEYWLAHIEALLENDKNPEMRTLAIRALAGCRSQRVLDLCEKQLTDESIKVRMAVCDVLAVRDEARSTELLGTTIGSESNEDVMMAAIAAVGKHQSPEAAQALKASLKSRNPAVRTAAVESLAQCTGKELGEDPQVWVAYLEGKAVDEQKKSFTRQMRDLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRJ5</accession>
    <name>A0A518IRJ5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Arginine transport ATP-binding protein ArtM</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">artM</name>
        <name evidence="6" type="ORF">Mal33_16980</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030802">
        <property type="entry name" value="Permease_MalE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02405">
        <property type="entry name" value="MlaE"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
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            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
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            <end position="423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="464"/>
            <end position="485"/>
        </location>
    </feature>
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        <location>
            <begin position="497"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="13"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="45"/>
            <end position="52"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
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    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV55719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="524" mass="57199" checksum="1F687C411C6F562A" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRJ8</accession>
    <name>A0A518IRJ8_9BACT</name>
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        <submittedName>
            <fullName evidence="4">Cold shock protein 2</fullName>
        </submittedName>
    </protein>
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="CSD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="39"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV55708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="65" mass="7089" checksum="31466B8E410DB3EA" modified="2019-10-16" version="1">MSQGTIKKITDKGFGFIDGERGDIFFHHSAVVEGSFESLREGQNVEYTEGSGPKGPRAENVRASE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRK2</accession>
    <name>A0A518IRK2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF58 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_16930</name>
    </gene>
    <organism evidence="3 4">
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        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <location>
            <begin position="21"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="domain" description="DUF58" evidence="2">
        <location>
            <begin position="212"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="396" mass="45245" checksum="F5CBF082460FC2E9" modified="2019-10-16" version="1">MGLSATPTDKLHRIKVRLTRSGYHFGFVALFTIVGAVVRDLNLLAILAGLLIGTLVMQWRFSRGTLHGLTIARQLPVEVFAGDLFSIRYRIRNLRKMLPAWFLQLDERIHSESQRRETASGRAALAYIGSQDEQTAAFQCRIAQRGRYLLGPLRFSTEFPFGLTRASRLIDRREEFVVYPRLGRLRKGWRGWMLSDQTGLVASRRRAGVNEGDFYGLRDWQNGDSRRWIHWRTTARIGELAVRQFEQQQRQQIALLVDLYQEVPSDESLERLVGFAATLMNEVLRNPETQVAFAITDGLVISNRNCRGLEFRRRVMSSLAMASRRPGPLLHDKLRELVGVSDTNWPLVVASTRPMNHQVLDSQDSAATVAGRLDLRWLNLADESSQQIFMETAHED</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRM2</accession>
    <name>A0A518IRM2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_17170</name>
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    <organism evidence="3 4">
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        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetia</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010269">
        <property type="entry name" value="T6SS_TssC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044032">
        <property type="entry name" value="TssC1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044031">
        <property type="entry name" value="TssC1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35565">
        <property type="entry name" value="PTHR35565"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05943">
        <property type="entry name" value="VipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18945">
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    </dbReference>
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        <property type="entry name" value="VI_chp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="67"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="domain" description="VipB_2" evidence="2">
        <location>
            <begin position="376"/>
            <end position="485"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="490" mass="54926" checksum="8A406CCB43095342" modified="2019-10-16" version="1">MSSLQTESEGGAAVAELSLMDQILDQTRALDDSERSRNQTYIEQFVAKVVDGNATVDKDVVTNITSWIAEIDHKLSVQLAEVMHCDEFQQLEGTWRGLHYLTQNSETGTSLKIRVMNVKKAELQKDLEKAVEFDQSTMFRKCYEEEYGQLGGEPYGMLVGDYHFGRTADDINLLRLISNVAAAGHAPFVAAADPNMFNMDSFTDLSGPRDLAKIFQGADYAAWRSFRDSEDSRYVALTMPNVLGRLPYGGDFKKVESFDFNEHVDGTDHSQYLWMSSAWAYATRVTDAFAKHGWFAQTRGVEGGGKVENLPVHTFPTDDGDVAMKCPTEIAITDRREFELSNLGFLPLLHAKNTDFAAFLGAQSCQKPKTYFEEDANANAELSSKINYLMCVSRFAHYLKVMARDKIGSSMERAECQEWLNDWISNYVCDPSTAGEETKAERPLSEARVEVAEIPGRPGWYEAIAYLRPHFQMETLGASMRLVAEVPKQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRN9</accession>
    <name>A0A518IRN9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">FG-GAP repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_17340</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.130">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013517">
        <property type="entry name" value="FG-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028994">
        <property type="entry name" value="Integrin_alpha_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011519">
        <property type="entry name" value="UnbV_ASPIC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13517">
        <property type="entry name" value="FG-GAP_3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07593">
        <property type="entry name" value="UnbV_ASPIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69318">
        <property type="entry name" value="SSF69318"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021850654" evidence="3">
        <location>
            <begin position="29"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="domain" description="UnbV_ASPIC" evidence="4">
        <location>
            <begin position="503"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV55755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="583" mass="62426" checksum="8C86F5CFCA59B848" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRS7</accession>
    <name>A0A518IRS7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Manganese transport system membrane protein MntB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">mntB_2</name>
        <name evidence="10" type="ORF">Mal33_17690</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the ABC-3 integral membrane protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046914">
        <property type="term" value="F:transition metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037294">
        <property type="entry name" value="ABC_BtuC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001626">
        <property type="entry name" value="ABC_TroCD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001367">
        <property type="entry name" value="Fe_dep_repressor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036421">
        <property type="entry name" value="Fe_dep_repressor_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022689">
        <property type="entry name" value="Iron_dep_repressor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30477">
        <property type="entry name" value="PTHR30477"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00950">
        <property type="entry name" value="ABC-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02742">
        <property type="entry name" value="Fe_dep_repr_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00529">
        <property type="entry name" value="HTH_DTXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47979">
        <property type="entry name" value="SSF47979"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81345">
        <property type="entry name" value="SSF81345"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="14"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="66"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="98"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="150"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="181"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="211"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="237"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="269"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="domain" description="Fe_dep_repr_C" evidence="9">
        <location>
            <begin position="368"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="411"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="411"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV55790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="440" mass="47301" checksum="92A044E50C16AB64" modified="2019-10-16" version="1">MNALQSLTWSLDGWIIVAGCLCALSAALLGNFLVLRKMSMLGDAITHAVLPGLAAAFLLTGNRSSIAMFVGAVIVGVLTALFSEWIRGFGKVDEGASMGVVFTSLFALGLVMIVQAADHVDLDPGCVLYGAIELTPLDLVRFAGLEMPRVVAVLSVVLCINVAFVALFYKELKLSSFDASLATALGFRATLIHYSLMTLVAITAVASFESVGNILVVAMFVVPPAAALMLTDRLSMVILLSSLIAIASGVLGHLSALVVPGWFGFRSTSTSGMMAVATGLLFVVAMLLGPRHGVLVKAVRRQMLSWRILAEDVLAVMFRMEEHRDHVVATGAQLGPRLMAGPLSTALLLRMHQGRGNVQPIDAGYRLTKRGRTQARWLVRSHRLWEQYLVDEAGVDTDRLHAKADALEHVTDAEMGDKLNRETRDTQTDPHGSPIPPLEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRW0</accession>
    <name>A0A518IRW0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TadE-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_17990</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012495">
        <property type="entry name" value="TadE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07811">
        <property type="entry name" value="TadE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="27"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="156" mass="17110" checksum="65A7B1E3805E8796" modified="2019-10-16" version="1">MNRSQIANTTDRPRRRRGKRRGQDRRGAAVVEFAVVANTLFLVIFTCVEFSRLNLIRNTAQNSAYYGARAAMVSGATAQDAIDTAENLLDAIGAKGVTVTVNDGAPLTSTTEKIVVKVEVKYNKNAFFAPLFIPDHKCVATSNVKAERYDFFFDGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IS07</accession>
    <name>A0A518IS07_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyl transferases group 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_18580</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="202"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="323" mass="36653" checksum="78B9EFA8B1F3667D" modified="2019-10-16" version="1">METGKRPVRIVARQNGVGLDRDVQLLQSTLPPGTLVENYSVRSLASIADRFKSLCCSPAPGSLPLNVLVERVPWAWVKNQGQSVLLPNQERFPKRLLHRLRDIDIVLCKSRHAEEIFSRHAKQARFIGFTSLDRRLPEVAPDYSKFFHLAGSSTLKGTQMLLELWSQNPQWPTLTIVQHPRHAPETVPANVALFKEYLTDAVLQRMQNEHGIHLCPSRSEGWGHYIVEAMSCAAVVVTTDAPPMNELVDESRGFLVPWNRSQPRHLGTDFFVDPAELQRVINEILATDTASLEQRGHAARGWFETNEVEFETRARELFLELLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISA9</accession>
    <name>A0A518ISA9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">N-carbamoyl-L-amino acid hydrolase</fullName>
            <ecNumber evidence="5">3.5.1.87</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">amaB</name>
        <name evidence="5" type="ORF">Mal33_19390</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="3">Binds 2 Zn(2+) ions per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M20 family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.87" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016813">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050538">
        <property type="term" value="F:N-carbamoyl-L-amino-acid hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010158">
        <property type="entry name" value="Amidase_Cbmase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001261">
        <property type="entry name" value="ArgE/DapE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32494">
        <property type="entry name" value="PTHR32494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001235">
        <property type="entry name" value="Amidase_carbamoylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01879">
        <property type="entry name" value="hydantase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00758">
        <property type="entry name" value="ARGE_DAPE_CPG2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="M20_dimer" evidence="4">
        <location>
            <begin position="213"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="93"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="191"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="384"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR001235-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV55960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="414" mass="44978" checksum="DFB3CC1A197BE9E3" modified="2019-10-16" version="1">MEIRVDLERIKRDILTLAKIGRRESDRGIYRMAFTDADIQGKRWLTQQIEQADLIASTDGAMNISGELSGTTDAPRVLVGSHIDTVPCAGALDGTLGVVVGLECLRTLRETGFQPDRTLELIAFSDEEGRFGGMFGSQAVCGQLNPQSLETTTDMNGVLLRDELGRHGHDALSALDAARVPESIAAYIELHIEQGPVLDRTKKAVGVVDEITGLFTWAVTLRGEANHAGTTPMEMRNDAFMGLADFAHEIPRILEENGSDRSRTTIGKAQILPGATNTVPGLVEFSLDVRDTSEAVLEELGTAFRKALSAIARRRNLMFEFAQKSYLRPVACHDAIVQLLMDQASKLELDHLRMPSGAAHDAQIMGSMVPVGMIFVPSKNGQSHSPAEWTAWSDIEAGANLMLQTLVQLSSATN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISE6</accession>
    <name>A0A518ISE6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATPase RavA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ravA_4</name>
        <name evidence="3" type="ORF">Mal33_19910</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011703">
        <property type="entry name" value="ATPase_AAA-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041628">
        <property type="entry name" value="ChlI/MoxR_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07726">
        <property type="entry name" value="AAA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17863">
        <property type="entry name" value="AAA_lid_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_3" evidence="1">
        <location>
            <begin position="46"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="AAA_lid_2" evidence="2">
        <location>
            <begin position="239"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="323" mass="35787" checksum="14B84046BBB2D7A5" modified="2019-10-16" version="1">MPQPTSPNVTEVTELSKKIISNVEQAIVGKRKQLVLSLVAWFSSGHILLEDVPGVAKTMLARALAKSVGCKFKRVQCTPDLLPSDISGTSIFNQKSGEFEFRKGPLFTQLFLADEINRATPRTQAALLEAMAESRVTVDGTTYQLEAPFLVVATQNPVDHEGTFPLPEAQLDRFLMRFSLGYPSLEEELRMLELLQVQHPIDGLKPVATAQQLVACQTAVRHVHVDRLVREYILQIVHDTREHEDLALGASPRATIALFRCAQAMAAIRGRSFVQPDDVKRIVGPVMNHRIIVRPESRLRKITAEKVMESILGEIAVPTVGEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISF8</accession>
    <name>A0A518ISF8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Outer membrane protein transport protein (OMPP1/FadL/TodX)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Mal33_19890</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell outer membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the OmpP1/FadL family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005017">
        <property type="entry name" value="OMPP1/FadL/TodX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35093">
        <property type="entry name" value="PTHR35093"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03349">
        <property type="entry name" value="Toluene_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV56010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="411" mass="43756" checksum="C19DF2BF3E685428" modified="2019-10-16" version="1">MFLLLGTTGVCFGQGAIVSSAGPVHRGMGGASTAAPISALGALYWNPATISGMEHGELEVGMDLLFTQHRVDSTFGPFSGSTEAEPGTFPIPNIGWVHHLENSPVSLGLSVNAVAGFKTNVQSDPTNPVMSPQPTGLGRVSSEASFLQIAPVISYALTDRISIGGGPVITSGQVGLEPFVFGSANSDSTYSSGRSSRYHWGGGLQAGVYFIPNEDWRFGASFKSPSWMEEFEFYGEDETGAPRELSAHIDLPMILSLGTAYAGFDKWLLAVDLRYIDYANADGFGDPATYDATGRLNGLDWSSVMAVAFGAQRAIGDRAFIRGGYSYNQNPVRESESFYNVATPLIYEHTLSVGGSYKLNEMLALNIAYSHFFENSRTGPIVMPGVGAIPGSSVTNEMSADVLSFGILMRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISG1</accession>
    <name>A0A518ISG1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 25">Na(+)-translocating NADH-quinone reductase subunit F</fullName>
            <shortName evidence="25">Na(+)-NQR subunit F</shortName>
            <shortName evidence="25">Na(+)-translocating NQR subunit F</shortName>
            <ecNumber evidence="6 25">7.2.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="24 25">NQR complex subunit F</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="23 25">NQR-1 subunit F</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="25 28" type="primary">nqrF</name>
        <name evidence="28" type="ORF">Mal33_19720</name>
    </gene>
    <organism evidence="28 29">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="28 29" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="28 29">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 25">NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 25">
            <text>a ubiquinone + H(+) + n Na(+)(in) + NADH = a ubiquinol + n Na(+)(out) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:47748"/>
            <dbReference type="Rhea" id="RHEA-COMP:9565"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="7.2.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="25">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
        <text evidence="25">Binds 1 [2Fe-2S] cluster.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 25">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5 25">Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="25">Cell membrane</location>
            <topology evidence="25">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 25">Belongs to the NqrF family.</text>
    </comment>
    <dbReference type="EC" id="7.2.1.1" evidence="6 25"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016655">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006814">
        <property type="term" value="P:sodium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00430">
        <property type="entry name" value="NqrF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008333">
        <property type="entry name" value="Cbr1-like_FAD-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010205">
        <property type="entry name" value="NqrF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00970">
        <property type="entry name" value="FAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000044">
        <property type="entry name" value="Cis_Diol_DH_RD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="SSF52343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01941">
        <property type="entry name" value="nqrF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 25" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="9" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="8 25" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="13 25" id="KW-0274">FAD</keyword>
    <keyword evidence="10 25" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="19 25" id="KW-0406">Ion transport</keyword>
    <keyword evidence="15 25" id="KW-0408">Iron</keyword>
    <keyword evidence="16 25" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="21 25" id="KW-0472">Membrane</keyword>
    <keyword evidence="12 25" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17 25" id="KW-0520">NAD</keyword>
    <keyword evidence="28" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="29" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="18 25" id="KW-0915">Sodium</keyword>
    <keyword evidence="22 25" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="14 25" id="KW-1278">Translocase</keyword>
    <keyword evidence="25" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="25" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="25" id="KW-0813">Transport</keyword>
    <keyword evidence="20 25" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="26">
        <location>
            <begin position="32"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="27">
        <location>
            <begin position="127"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="binding site" evidence="25">
        <location>
            <position position="67"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="25">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="25">
        <location>
            <position position="76"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="25">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00002972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005570"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00019729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00023075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="ARBA" id="ARBA00030032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="ARBA" id="ARBA00030787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="25">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="26">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="27">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="28">
        <source>
            <dbReference type="EMBL" id="QDV55993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="29">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="406" mass="45259" checksum="E030BC0CA0CCAA43" modified="2019-10-16" version="1">MTIFFGVLMFTGVIFLLVGVILGAKKILVPSGDVKININDQKDISVPAGGKLLGALADAGIFVSSACGGGGTCAQCKVKVLDGGGEILDTERNHISKKEAACGERLSCQVAVKQDMKVEVPHEAFETKKWECTVRSNNNVATFIKELVLELPEGEDVAFKAGGYIQIECPPHTVHYKDFDIESKFHEDWDKFNIWRYTSVVDEEVVRAYSMANYPGEKGIIMLNVRVASPPPRAPEDTPPGKMSSYIFGLKPGDKVTISGPYGEFFIKDTDSEMVYIGGGAGMAPLRSHLFELFRNLKTGRKVSYWYGGRSHRELFYVDHFRKIEEEFPNFKFNIALSEPLPEDNWTGYRGFIHQVLYNEYLKDHPAPEDIEYYICGPPMMNAAVFNLLDDLGVEKENVAYDDFGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISX0</accession>
    <name>A0A518ISX0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Haloalkane dehalogenase</fullName>
            <ecNumber evidence="2">3.8.1.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">dhaA_1</name>
        <name evidence="2" type="ORF">Mal33_21720</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.8.1.5" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018786">
        <property type="term" value="F:haloalkane dehalogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="37"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="305" mass="34252" checksum="95B80F6CFEA4BE4C" modified="2019-10-16" version="1">MNSDAIWQNEYPFTSRWHEADGHRYHFISEGAGDQTILAVHGNPTWSFYWRNVVQRFSDSRRVVAVDHIGCGMSDKPQEYDYCLETHAANLSSLIEAEDLRRITLLAHDWGGAIGLLALTKHVDRFERIVLLNTGAFPPPYVPWRIGVLRCPVLGPLAIRGLNAFAGPAVTMAMSRRSLSPEARAGLLAPYKNWADRVAIDRFVQDIPMSPSHRTWQPLERLEAALPSLSHLPTMLIWGMKDWCFRPECMDRIKKSMPHAQTVPIADAGHYVMEDATEEVLDSIDSFFQSTDAPSATSATSHPST</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISX1</accession>
    <name>A0A518ISX1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_21660</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="286" mass="33614" checksum="CDD8AC6804C6A627" modified="2019-10-16" version="1">MLPKEELVEQAYFFRILSERMGERLAMQDLLKQVKFELLTSTKLPMAVDFLLTELLHGGAMGPAMRRMQHYFTSFQTYLVEEAEFERGRFGMQTAVKVLQFDAEYRSGQPSRQGCFLYQFEALCRNRLRYDQGLKAMSEDPIYDADWKQWLLEVRHQIGLVDLADMIFLRSEEYVQRKRAIEGPEFEPKLPPLFGQHEGRMAMANHRKDPLFLFAAMQRHLGYPAVPRLAPPDPTAEIVPQLQRRMERLETRMKIMEEEQRHGLDITKFYVDPHKPPSDHDSDIDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IT61</accession>
    <name>A0A518IT61_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_22570</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="190" mass="21693" checksum="1883482200AD95CE" modified="2019-10-16" version="1">MQNPFETIRVEVATMSHLLAIAFFFLPVIVGLTSCVTAYGDDPPFRIKTKRDDDKVEVTVENDKGVISVRSPFGLSQAIIERSGNKWPDIVTLRLHLKGLEKFKVTNGKDTLEAAVSSQYGKVRLWKDGKEDRALDSKHLYWTEIRMVGKDGEPVKTIPLKDGYFEMQLPKALFEHNPPSITLHWIDFYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IT76</accession>
    <name>A0A518IT76_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Efflux pump periplasmic linker BepF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">bepF</name>
        <name evidence="6" type="ORF">Mal33_22780</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022213448" evidence="4">
        <location>
            <begin position="24"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="domain" description="HlyD_D23" evidence="5">
        <location>
            <begin position="119"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="39"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="153"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="63"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV56296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="420" mass="46227" checksum="C097FA7D29E4A139" modified="2019-10-16" version="1" precursor="true">MQTPTLPAITLMLPLILCVPACDDVVALRDTVLHSGTQLADLPSSTHPHGAASHPTAHAAAHADAGHAEDSHQTSEHDSEAHAEGGHHVAHKIIVTSPVAKDVVSTQQYVCQIHSWRHIEVKALEGGYLERIAVNEGQAVKQGDLLFKILPTLYQARLESDQAEAQLAQIELQNTERLYHQNIVAMPEVALARAKLAKAQAKVNLALAELDFANVKAPFDGIVDKQYEQLGSLIEEGAMLTTLSDNSVMWAYFNVPEARYLAYQADPNKDDVKVELLLADGNKFSQVGRIGAIEADFNNETGNIAFRGDFPNPSHLLRHGQTGTVLLSRVINGAVVIPQRATYEILAKKYAFVVDDDNVVHQREITIQSEQDDIFLIKEGLSATDKIVLEGIRQVRDGDRVEYEFQDPEDVLRNLKHHAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITA3</accession>
    <name>A0A518ITA3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">Ornithine carbamoyltransferase</fullName>
            <shortName evidence="5">OTCase</shortName>
            <ecNumber evidence="3 5">2.1.3.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">argF</name>
        <name evidence="9" type="ORF">Mal33_23060</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>carbamoyl phosphate + L-ornithine = H(+) + L-citrulline + phosphate</text>
            <dbReference type="Rhea" id="RHEA:19513"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
            <dbReference type="ChEBI" id="CHEBI:57743"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="EC" id="2.1.3.3"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.1.3.3" evidence="3 5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016597">
        <property type="term" value="F:amino acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004585">
        <property type="term" value="F:ornithine carbamoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1370">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01109">
        <property type="entry name" value="OTCase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006132">
        <property type="entry name" value="Asp/Orn_carbamoyltranf_P-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006130">
        <property type="entry name" value="Asp/Orn_carbamoylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036901">
        <property type="entry name" value="Asp/Orn_carbamoylTrfase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006131">
        <property type="entry name" value="Asp_carbamoyltransf_Asp/Orn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002292">
        <property type="entry name" value="Orn/put_carbamltrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024904">
        <property type="entry name" value="OTCase_ArgI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00185">
        <property type="entry name" value="OTCace"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02729">
        <property type="entry name" value="OTCace_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00100">
        <property type="entry name" value="AOTCASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00102">
        <property type="entry name" value="OTCASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53671">
        <property type="entry name" value="SSF53671"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00658">
        <property type="entry name" value="orni_carb_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="OTCace_N" evidence="8">
        <location>
            <begin position="2"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="OTCace" evidence="7">
        <location>
            <begin position="148"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Carbamoyl phosphate binding" evidence="5">
        <location>
            <begin position="128"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Ornithine binding" evidence="5">
        <location>
            <begin position="225"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Carbamoyl phosphate binding" evidence="5">
        <location>
            <begin position="261"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>carbamoyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>L-ornithine</name>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="221"/>
        </location>
        <ligand>
            <name>L-ornithine</name>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="289"/>
        </location>
        <ligand>
            <name>carbamoyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV56324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="311" mass="34214" checksum="C0455847B9E3239E" modified="2019-10-16" version="1">MRHLRTLFDLSPAEVKQILATALTLKTRLAEGDRTPILPGRVLGLLFEKPSLRTRVSFEAGMAQLGGSSLFLGSDVGWNTRETASDFTRVIGQYLDVVVCRAKAHDRVEELAQFNALSVVNGLTDLSHPCQALADMLTILETFGTCSGKHIVFVGDGNNVARSLALICAMLDARFTLACPAGYEIDAPWLERIRSEYPDAQIQQVRDPMPAVADADAIYTDVWTSMGQEAERAERVKIFQDYQVNEALQAAAPKECQILHCLPAVRGEEITDGVIESPQSAIVQQAGNRMHAQKALLVWLLEPNWIAENVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITD0</accession>
    <name>A0A518ITD0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cystathionine gamma-lyase</fullName>
            <ecNumber evidence="4">4.4.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">mccB</name>
        <name evidence="4" type="ORF">Mal33_23230</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 3">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the trans-sulfuration enzymes family.</text>
    </comment>
    <dbReference type="EC" id="4.4.1.1" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004123">
        <property type="term" value="F:cystathionine gamma-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080146">
        <property type="term" value="F:L-cysteine desulfhydrase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044540">
        <property type="term" value="F:L-cystine L-cysteine-lyase (deaminating)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019346">
        <property type="term" value="P:transsulfuration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00614">
        <property type="entry name" value="CGS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000277">
        <property type="entry name" value="Cys/Met-Metab_PyrdxlP-dep_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11808">
        <property type="entry name" value="PTHR11808"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01053">
        <property type="entry name" value="Cys_Met_Meta_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001434">
        <property type="entry name" value="CGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00868">
        <property type="entry name" value="CYS_MET_METAB_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="2">
        <location>
            <position position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR001434-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV56341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="381" mass="40744" checksum="FDB58B95EBB5A656" modified="2019-10-16" version="1">MKFRTRAIHDGNSIDPQTGAVVPPIHLASTFRQPGAGEWGEFDYSRSGNPTRSNLQATLNSLEGAVGSLAFSSGMAATHCVTMLLGNGDHVVAGKDIYGGTYRLLHKICDRNGISVTLVDMTDLDAVAAAIQPNTKLLWAETIGNPLFSIPNLTALAELAHSRGALIGVDNTFGTPVLVRPLEFGIDIVMHSATKYLGGHSDCLGGTLSVADKELYDRLYFVQNATGAVLDPFSSFLIGRGLKTLDVRIREQSKTAARLADWLAAHPRVSRVYYPGLTSHPGHELAARQFDGIYGAMLGFELAGDFKATAAMVGKTHLFHLAVSLGAVESLIEQPASMSHASYDPADRAKAGISDALVRLSVGLEDFDDLRQDIEQAIESV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITG9</accession>
    <name>A0A518ITG9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">UvrABC system protein C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">uvrC_2</name>
        <name evidence="2" type="ORF">Mal33_23590</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000305">
        <property type="entry name" value="GIY-YIG_endonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035901">
        <property type="entry name" value="GIY-YIG_endonuc_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01541">
        <property type="entry name" value="GIY-YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00465">
        <property type="entry name" value="GIYc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82771">
        <property type="entry name" value="SSF82771"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50164">
        <property type="entry name" value="GIY_YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GIY-YIG" evidence="1">
        <location>
            <begin position="47"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="402" mass="46311" checksum="DB80E855EC797981" modified="2019-10-16" version="1">MDLHQPAGLFEGFGPNPLDPLGPRTTHRVAATSTAELRTLVRQQCPKSPGIYGMLDRSGQLIYVGKSKRLRIRLLSYFSPRNAEEKAGRIIQAAQTVLWETQPSEFAALLREQQLIRRWTPRWNVQEIPKRQRPVYLCLGGAPAPYFFLDAMPPADVVASEGPFRGAGKMQRAVDALNNFYRLRDCSSKQELYFADQLQLFELEQRPGCLRYEIGRCSGPCVGQCTRRQYDQQVAEAESFLDGFHAAPLETIRETIHRAAEMRQYELAGRMSRDLVSLEYLHRKLMFLAAARRKYTFVYSVPGHESEPDAQQNHRGVWYLIRRGEVCESIVAPRCPEEFQRARRRVTHWKRVLADPENHRAASPFPFTLSLVAQWLRKQPQELERTFHPSEAGRRYRALARS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITI3</accession>
    <name>A0A518ITI3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_23860</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="330" mass="36292" checksum="1ABB6D533DC39013" modified="2019-10-16" version="1">MNDRQTILDRHDCNAIDAISRAEIAPHAINGKTVSAAMQKRVLKLLASYSSDRCWLSIESIAEQLEHNERTVRLAIQSLLQKDLLIESGHRNRRTRCVHWTQVGRLIRSDGGDSGGDPGRHGAEKHARDVSHDPVESVPRPVSSGHEVSHDPVHPGLGARTYQRPRNQSPSSPCNRPTTAKVLDPNWEPAVEALLAVGLAHTAKAIALAKSAGMAPEELVDLVLVVQHVGQLRPGAIIARLRDGCWPIDGIPDADEIRRRMQGKAEAIRQARHEAAETAENRPQRWIIDGLVGRDLRKAGLIDLAADAELQAANRMDEVDRLRCDRLALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITN5</accession>
    <name>A0A518ITN5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_24370</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="246" mass="27766" checksum="98A1C0D6B1225AB5" modified="2019-10-16" version="1">MFLANPPEYSQLESEFAWEKTHFAERQRRETAEPVMTRVSSFAKNVKSFIAPKRNKIASVAFDVMQTQDHSKPLKVLDIGCGWGDLMLEVHCRFAQLGRDVLPIGIEVSKELALLSEEKIAPIGGKVICANAIDGISDLEPDSIDLALMSSFLEHECQPLQLLQRLHTVLAPNGAVVLKVPNFDCWNRLIRGRKWCGFRYPDHVNYFTPKTLQRLAHESQFAVARQNVLDKFPLSDNMYAVLAKSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITQ8</accession>
    <name>A0A518ITQ8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Type I site-specific deoxyribonuclease</fullName>
            <ecNumber evidence="3">3.1.21.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">hsdR_2</name>
        <name evidence="14" type="ORF">Mal33_24630</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endonucleolytic cleavage of DNA to give random double-stranded fragments with terminal 5'-phosphates, ATP is simultaneously hydrolyzed.</text>
            <dbReference type="EC" id="3.1.21.3"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the HsdR family.</text>
    </comment>
    <dbReference type="EC" id="3.1.21.3" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="REBASE" id="355352">
        <property type="entry name" value="PbaMal33ORF24600P"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009035">
        <property type="term" value="F:type I site-specific deoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007409">
        <property type="entry name" value="Restrct_endonuc_type1_HsdR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040980">
        <property type="entry name" value="SWI2_SNF2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04313">
        <property type="entry name" value="HSDR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18766">
        <property type="entry name" value="SWI2_SNF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="8 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0680">Restriction system</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="13">
        <location>
            <begin position="278"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="217"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="801"/>
            <end position="828"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="QDV56473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1047" mass="117122" checksum="DAE1D33D4D60B77E" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITS2</accession>
    <name>A0A518ITS2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_24760</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="162"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="346" mass="37846" checksum="318191D7E422880C" modified="2019-10-16" version="1">MRGAKQQTIDFTRGDQLGLLKSLPIKSADVGDGKAAARVSSRMALSVLRAIDDYCGKSGRCWASAATIGADINCSERSVRRAIRLLESEQLIVIEHRHGRSPIMVINWGEISLRVSKANATATPDILTSGNPGHFFANPGQSDMNPGQSDMNPGQYVRRTVSNRKRTALPPPPQNTSGSEGSDFDLPSPIEETATWHHVAQRLALSGIREWRRALADLKAAVDVEHATRLLDVYTDRVGAYGPFALYRRCRNASAVLPPEDGWPDPKPESAYARDYVAAERILATVHRDAANRESLGYDKPSPKAIAAVAADRMAAAGLGCDLLPERYRKLLDHRLQTGRERQTCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITT2</accession>
    <name>A0A518ITT2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Site-specific DNA-methyltransferase (adenine-specific)</fullName>
            <ecNumber evidence="2">2.1.1.72</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">hsdM_1</name>
        <name evidence="6" type="ORF">Mal33_24600</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2'-deoxyadenosine in DNA + S-adenosyl-L-methionine = an N(6)-methyl-2'-deoxyadenosine in DNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:15197"/>
            <dbReference type="Rhea" id="RHEA-COMP:12418"/>
            <dbReference type="Rhea" id="RHEA-COMP:12419"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90615"/>
            <dbReference type="ChEBI" id="CHEBI:90616"/>
            <dbReference type="EC" id="2.1.1.72"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.1.1.72" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="REBASE" id="355353">
        <property type="entry name" value="M.PbaMal33ORF24600P"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008170">
        <property type="term" value="F:N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009007">
        <property type="term" value="F:site-specific DNA-methyltransferase (adenine-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022749">
        <property type="entry name" value="D12N6_MeTrfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003356">
        <property type="entry name" value="DNA_methylase_A-5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038333">
        <property type="entry name" value="T1MK-like_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12161">
        <property type="entry name" value="HsdM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02384">
        <property type="entry name" value="N6_Mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HsdM_N" evidence="5">
        <location>
            <begin position="6"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="domain" description="N6_Mtase" evidence="4">
        <location>
            <begin position="151"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="495"/>
            <end position="526"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF12161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV56470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="598" mass="67699" checksum="417E7632D314ADEB" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITU4</accession>
    <name>A0A518ITU4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_25000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="157" mass="16378" checksum="299E8AA72FC29971" modified="2019-10-16" version="1">MIVVLATGISGTEFAFDPGTLLDVSDTAAARLIAGGLANPVVDAEIDPAKVKTLPRSRRQSVAPSVVDASNTVDNIDTNSMDVDVDLADLVDYGLDPKVHARLIAGLAELDATTRPSTGRELIQWSADNGGMGELAEVGAASVRDIHVVFRSLGLIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITX3</accession>
    <name>A0A518ITX3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_25010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="105" mass="12080" checksum="D91E094061D471DA" modified="2019-10-16" version="1">MVSKANLRRYVELDNRRTQLLARLASIDEEYFAIKDDIESDLECRHNSRSVEMVGYQVTVKRGERVVPWERELRSVLGDQAIARLIRSAPRSTTLQVTEAACNTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IU25</accession>
    <name>A0A518IU25_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative oxidoreductase CzcO</fullName>
            <ecNumber evidence="1">1.-.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">czcO_2</name>
        <name evidence="1" type="ORF">Mal33_25850</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.-.-.-" evidence="1"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="572" mass="65606" checksum="B1D1FB6BFD3EA0BF" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IU47</accession>
    <name>A0A518IU47_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_26060</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="87" mass="10133" checksum="8D02986841071642" modified="2019-10-16" version="1">MMLSCKEISKLVSESLETKLTLRQRVELWMHLRLCRLCAAFRRDVDTLHLRTQQHVEELDSDRSVAKAKLSAGARQRIKQAIEARND</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IU57</accession>
    <name>A0A518IU57_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ATP-dependent Clp protease ATP-binding subunit ClpX</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6 9" type="primary">clpX</name>
        <name evidence="9" type="ORF">Mal33_26170</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the ClpX chaperone family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00175">
        <property type="entry name" value="ClpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004487">
        <property type="entry name" value="Clp_protease_ATP-bd_su_ClpX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046425">
        <property type="entry name" value="ClpX_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010603">
        <property type="entry name" value="Znf_CppX_C4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038366">
        <property type="entry name" value="Znf_CppX_C4_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06689">
        <property type="entry name" value="zf-C4_ClpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00994">
        <property type="entry name" value="zf-C4_ClpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00382">
        <property type="entry name" value="clpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51902">
        <property type="entry name" value="CLPX_ZB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 6 7" id="KW-0143">Chaperone</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="ClpX-type ZB" evidence="8">
        <location>
            <begin position="10"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="22"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="25"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="130"/>
            <end position="137"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV56625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="429" mass="47391" checksum="E0FAE84E4975752A" modified="2019-10-16" version="1">MTSKDITTGRRSGGTTKKNAFCSFCRKSYRDVGPLVEGPGDVYICSECIELCQSILDQEQRRRGPSKKLFDDIPAPRELVSHLDQYVIGQQAAKKVLSVAVHNHYKRLTAEWEGTSDVEIEKSNVLMVGPTGCGKTLLARSLARMLNVPFAIGDATTLTEAGYVGEDVENLLLKLLHAADFDLEAAQRGILYIDEVDKIGKTGGNVSITRDVSGEGVQQSLLKMLEGTVANVPPQGGRKHPEQQYIQMDTSNILFICGGTFVGIEEIIRKRQGHRTLGFGSDAGHRDESDVASLLAQVSSDDILEYGLIPELVGRMPVVTHLAPLDEEGLLNVLREPRNALTKQYQALFQMEHCEVEFTEDALRVIAQRAQEKGTGARGLRSIIEEVMLDIMYELPDQERGSVYTIDESIVTGRRKLFQMPEQPQTKSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUC5</accession>
    <name>A0A518IUC5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_26940</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010869">
        <property type="entry name" value="DUF1501"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07394">
        <property type="entry name" value="DUF1501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022102970" evidence="1">
        <location>
            <begin position="22"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="422" mass="45488" checksum="443DF8D20F221A6B" modified="2019-10-16" version="1" precursor="true">MKRRHFLQSTAAAAAATPLLASQTNAMPMGKAEHCVMIWLGGGMAQIDTFDPKAMGDAKAKKAGSYYKAIDTAVPGVQVCEHLSGTARMMEQVTALRTVHHDVVDEHAAATNRMHTGRPTTGTVQYPSIGSIIADQRGAAGEGVPAYMLIGYPNLTRGPGFLGQKAGFVYLTDIKSGPAGLARPAEITDGRQARREQLLTAVRSAGRKRFAGDKLYADYDSAVAESLRLSGPDFMKSFDLSNESDDLRNQYGDGFGQRLLMTRRLFQSGVRFIEVSHNMNFRNGTGWDTHNDGQLNQHVLIQELDRSMSALMADLEAHKMLDKTLIVINSEFGRPAQFDSGGGRGHYSKNFSMVLAGGGLRHQGAYGVSDELAMNAVENPISVPDAFATIMATMGIDTSINLYDGDRPVPITDGGVPIASLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUG1</accession>
    <name>A0A518IUG1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_27160</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039060">
        <property type="entry name" value="Antitox_HigA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40455">
        <property type="entry name" value="PTHR40455"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="142" mass="16032" checksum="C72633606145D60A" modified="2019-10-16" version="1">MQNMTKSTRKRSEPLHPRLIKSAAEHDRALARVEELFTAKPGTAEGDELELWLLLIDAYESKEFPIDLPDPIEAIRFRMEQGNLKQKDLVPIFGSKGKVSEVLNGKRELSLTMIRNLVNQLGIPAEVLLQQRTAKISPSLSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUJ3</accession>
    <name>A0A518IUJ3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Inner membrane protein YiaV</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">yiaV_1</name>
        <name evidence="3" type="ORF">Mal33_27650</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039562">
        <property type="entry name" value="MFP_biotin_lipoyl_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13533">
        <property type="entry name" value="Biotin_lipoyl_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="domain" description="Biotin_lipoyl_2" evidence="2">
        <location>
            <begin position="63"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="457" mass="47554" checksum="9173A8EF5B112B0F" modified="2019-10-16" version="1">MIAFMLTIYVAVVVLLFKMKLVKPNPYPIALILVAGIFVIGGPAVAWTLSAPVSPRVVTTQYVVQLVPYVKGQVAKVHAQANVPMKKGDLLLEINPTPYQNALDQATAQLQAAREGLKQAEAGVDVAKASVASAAAGVQQATAAVGQSKAVVSNALASIKRAKAGIASAEAGVTKAKAADDLAKTEEQIAVNLQKTDAGAISALRVTQSVQSRQAADAALQAAETGVNEAQAALLQAEAGLSQSQAAEQQAAAGLVAARAVQQQVDASESQAMLGVKIAASKVQAAEAQVSDAQFNLGQCKMLAPADGYVVNWTVQEGTMLVPVPLAAAGTFINTEQTFIVASYPQNWLMNVESGDDVELVLNPFPGRLFKGKVDQVIPATGEGQFDPSKSVPLASQVGSHGFLAVKILLDQDQTIPSLPLGAGGTVAIYTDHGKPVHIISKVAIRMQKWLLYIMPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUM2</accession>
    <name>A0A518IUM2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_27760</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011465">
        <property type="entry name" value="DUF1571"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07608">
        <property type="entry name" value="DUF1571"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="304" mass="34382" checksum="A52BDCB6D3E99D73" modified="2019-10-16" version="1">MNRNQILLLIVIGQGLVIALLFAIRFKRESADPEDSIAVVEVAEQMQQAPSNARESTLAEALTIARAGLAEMRANMTDYRGRVVKRERIKGQLANEYEMEIKVQCRRLVEEEVVAPMRVYLKFLQPQSVAGREVIWAEDQNDGRLIAHEPGLLNVAQASLDPHGERAMEGNLYPITEIGLVNLVVQLIARGENDLEESQVRVTLAEGQTIGDRECQQIRIELIQPHDELNFQYAEIFIDSERQIPLRYAAYGWPEDAATGDHDGPPELLEEYTYYDIQTNVGLTDADFDPNNEAYDFPAFRINL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUN8</accession>
    <name>A0A518IUN8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tricarballylate dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_27970</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="488"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="516"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="530"/>
            <end position="553"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="553" mass="62066" checksum="695E8C00DC0E78B5" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUP7</accession>
    <name>A0A518IUP7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_28130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="188"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="217"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="246"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="287"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="320"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="355" mass="39516" checksum="1B164EABB9C8BB63" modified="2019-10-16" version="1">MSAEVSPMPVRSRVAAVPAARDQASGFLFSPLIDLLFIANICWPLILFIDGFGGATTHQSLTFWQIYFITTPHRWITLVLVGLDKKKTADRRGLFIGLALAIVAGCLCLRFGTGTLLCLGVIDYIWNAWHFSSQHHGIYRIYQRRQPQHRDNGASWGEKALFRGFVLYVIARVAGWGWTEGPFPGSDAFAPLDLIVAGIPLYFVLRQLFQMRSLAASGIASFAYLASMMGLFTAMLYASHLQDSQLVLRLALASAIFHSLEYLAIVTWSVQQSRGKPASTGDAQPGVFAYLAGMWMLFLVAFVVLIGVGNYLLSRGYFEVWLLVNMIVAFWHYCFDGLIWKSPKRTRADLAVEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUP9</accession>
    <name>A0A518IUP9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_28160</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022009059" evidence="1">
        <location>
            <begin position="24"/>
            <end position="825"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="825" mass="92279" checksum="ED51E2F2845AA163" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUQ4</accession>
    <name>A0A518IUQ4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Biopolymer transport protein ExbD/TolR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Mal33_28190</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the ExbD/TolR family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003400">
        <property type="entry name" value="ExbD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30558">
        <property type="entry name" value="PTHR30558"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02472">
        <property type="entry name" value="ExbD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="125"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV56819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="250" mass="26774" checksum="F36A15224915EACA" modified="2019-10-16" version="1">MSMTCPRCGAQTQGVRCESCGADLPTADAIPVASEPSAAEPIEIEATDDGSDAAEAETVEAAAAEPAATEAHASVETTATAHHHGHAMAEAVNATNFGIEEEVAPDDLQMKGKIRDDSELDMTPMVDVTFLLLIFFMVTASFSLQKSITMPREQSEAPSTNQQDEPEEEIDLVTVQIDEFNSFTVLAADWEREVPGKQNLIRALKEAKPESEARLKIEVHEDAVIEAVVDAMDAGAEVGFSEIQKSEVKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUS5</accession>
    <name>A0A518IUS5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UPF0235 protein Mal33_28450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_28450</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the UPF0235 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00634">
        <property type="entry name" value="UPF0235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003746">
        <property type="entry name" value="DUF167"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036591">
        <property type="entry name" value="YggU-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13420">
        <property type="entry name" value="PTHR13420"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02594">
        <property type="entry name" value="DUF167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01152">
        <property type="entry name" value="DUF167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69786">
        <property type="entry name" value="SSF69786"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="100" mass="10820" checksum="CA112F280AC70B96" modified="2019-10-16" version="1">MIETTPRENQLIFAIHVSAGSRRNEVGGQHDGALRVAVTQAPEKGKANAAIIKLLAKTLGISKSQLEIISGDTHRRKTIAATQIDPQQIDQQLQTLATIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUV6</accession>
    <name>A0A518IUV6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 10 11">Ribulose-phosphate 3-epimerase</fullName>
            <ecNumber evidence="7 10 11">5.1.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">rpe_1</name>
        <name evidence="10" type="synonym">rpe</name>
        <name evidence="15" type="ORF">Mal33_28740</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10 11">
            <text>D-ribulose 5-phosphate = D-xylulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:13677"/>
            <dbReference type="ChEBI" id="CHEBI:57737"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="EC" id="5.1.3.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10 13">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="10 13">Binds 1 divalent metal cation per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="10">Carbohydrate degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 10 11">Belongs to the ribulose-phosphate 3-epimerase family.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.1" evidence="7 10 11"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00588">
        <property type="reaction ID" value="UER00646"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004750">
        <property type="term" value="F:D-ribulose-phosphate 3-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019323">
        <property type="term" value="P:pentose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00429">
        <property type="entry name" value="RPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02227">
        <property type="entry name" value="RPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026019">
        <property type="entry name" value="Ribul_P_3_epim"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000056">
        <property type="entry name" value="Ribul_P_3_epim-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11749">
        <property type="entry name" value="PTHR11749"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00834">
        <property type="entry name" value="Ribul_P_3_epim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001461">
        <property type="entry name" value="RPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01163">
        <property type="entry name" value="rpe"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01085">
        <property type="entry name" value="RIBUL_P_3_EPIMER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="13" id="KW-0170">Cobalt</keyword>
    <keyword evidence="9 10 11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="13" id="KW-0464">Manganese</keyword>
    <keyword evidence="8 10 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="10 14">
        <location>
            <begin position="153"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="182"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10 14">
        <location>
            <begin position="204"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10 12">
        <location>
            <position position="46"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="10 12">
        <location>
            <position position="182"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10 14">
        <location>
            <position position="19"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10 13">
        <location>
            <position position="44"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10 13">
        <location>
            <position position="46"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10 13 14">
        <location>
            <position position="77"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10 13">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00009541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR001461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR001461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR001461-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR001461-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="QDV56873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="232" mass="24991" checksum="0BCD280E77B5F491" modified="2019-10-16" version="1">MTNPRVKQLFEAAPAILPSLLQCDFGNLEREVRRLEDDGCQGLHLDVMDGVFVPNISYGMPIVDAIRKLTDLPLDVHLMIQDPGKYAQAFSDAGADLLTFHVEAVDEIAPVIDNVRSLNMGTGLVLNPGTAIDAVTPFLDQIDVVLVMSVDAGFGGQAFNPVAIDKLKALRAIKPDLILEIDGGVNLETIGSCREAGADLFVVGSAIFRSSDYAAALDRLRAEVQRHDPHSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IV46</accession>
    <name>A0A518IV46_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">4-hydroxythreonine-4-phosphate dehydrogenase</fullName>
            <ecNumber evidence="4">1.1.1.262</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">4-(phosphohydroxy)-L-threonine dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4 5" type="primary">pdxA</name>
        <name evidence="5" type="ORF">Mal33_29360</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>4-(phosphooxy)-L-threonine + NAD(+) = 3-amino-2-oxopropyl phosphate + CO2 + NADH</text>
            <dbReference type="Rhea" id="RHEA:32275"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57279"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58452"/>
            <dbReference type="EC" id="1.1.1.262"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="4">Binds 1 divalent metal cation per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Cofactor biosynthesis; pyridoxine 5'-phosphate biosynthesis; pyridoxine 5'-phosphate from D-erythrose 4-phosphate: step 4/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="4">The active site is located at the dimer interface.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the PdxA family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.262" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00244">
        <property type="reaction ID" value="UER00312"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050570">
        <property type="term" value="F:4-hydroxythreonine-4-phosphate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042823">
        <property type="term" value="P:pyridoxal phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008615">
        <property type="term" value="P:pyridoxine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00536">
        <property type="entry name" value="PdxA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037510">
        <property type="entry name" value="PdxA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005255">
        <property type="entry name" value="PdxA_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30004">
        <property type="entry name" value="PTHR30004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04166">
        <property type="entry name" value="PdxA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00557">
        <property type="entry name" value="pdxA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0520">NAD</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="3 4 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-0664">Pyridoxine biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="4">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="213"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="269"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="277"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="286"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="295"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV56935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="341" mass="36311" checksum="73BA7020C87FFB68" modified="2019-10-16" version="1">MKPRLAITTGDPAGVGPELALKILGDREITDRCVPILFGDLAILQSVGQRLSLPLPQQIVPRTAGLAAIAKIDQPAIFDFASPLDGFRPGIVDRATGAASFAYVVDAIDAALAGQVDAIVTGPIQKEAWHAAGIEFPGHTELLAQRSQADRCCMMLTSHDVSCALVTVHVGLCEVPELLSTEKILQTIRLAHAAISRQRGRPARVAVCGLNPHAGEGGMFGKQEEERWIVPAIEAARSEGLSVTGPLPADTAFVPAMRRQTDVYVCMYHDQGLIPLKTLAFDEAVNVTLGLPIVRTSVDHGTALDIAWQGIANDTSMKQAIRMAIDLAKNESPEEPAKANT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IV95</accession>
    <name>A0A518IV95_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cupin superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_30100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041667">
        <property type="entry name" value="Cupin_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13621">
        <property type="entry name" value="Cupin_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00558">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="JmjC" evidence="1">
        <location>
            <begin position="94"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="296" mass="33683" checksum="89C8864B08B3E449" modified="2019-10-16" version="1">MLQPLPTALSQDHLCDLDQQKFIDDFNRRPFKIGHQLSDHSLFALESLIALSKDLPADRVEYNAGNLPVSQDPTSTPQNGLSVEETIQRIQQCQSWLVLKNVELNNQYGDLLDQCLDQVKPLAALVSEGMTHKQGFIFISSPGSVTPFHIDPENNFLLQIRGTKKVWMFGQNDREVLPETQVEDFFSGAHRNMQFEERFRERGEQFDLAPGEGLHFPVVAPHYVENGPEVSVSFSITFQTQDSSDRQTLHRFNRHLRRIGLTPSNVGERPGRDNAKLAMLRTLRKVKNIVRRPADA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVK0</accession>
    <name>A0A518IVK0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Dockerin type I repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_31150</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007156">
        <property type="term" value="P:homophilic cell adhesion via plasma membrane adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002126">
        <property type="entry name" value="Cadherin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041690">
        <property type="entry name" value="Cadherin_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002105">
        <property type="entry name" value="Dockerin_1_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036439">
        <property type="entry name" value="Dockerin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045474">
        <property type="entry name" value="GEVED"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006626">
        <property type="entry name" value="PbH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040853">
        <property type="entry name" value="RapA2_cadherin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17803">
        <property type="entry name" value="Cadherin_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17892">
        <property type="entry name" value="Cadherin_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00404">
        <property type="entry name" value="Dockerin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20009">
        <property type="entry name" value="GEVED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00710">
        <property type="entry name" value="PbH1"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63446">
        <property type="entry name" value="SSF63446"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50268">
        <property type="entry name" value="CADHERIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cadherin" evidence="2">
        <location>
            <begin position="5922"/>
            <end position="6059"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2147"/>
            <end position="2171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="3324"/>
            <end position="3352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="3480"/>
            <end position="3513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="5443"/>
            <end position="5475"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="6632"/>
            <end position="6653"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="2152"/>
            <end position="2171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="3480"/>
            <end position="3509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="5443"/>
            <end position="5460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="6653" mass="696794" checksum="8A9A8E8BB432991E" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IW04</accession>
    <name>A0A518IW04_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">30S ribosomal protein S5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">rpsE</name>
        <name evidence="10" type="ORF">Mal33_32750</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the universal ribosomal protein uS5 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000851">
        <property type="entry name" value="Ribosomal_S5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005712">
        <property type="entry name" value="Ribosomal_S5_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005324">
        <property type="entry name" value="Ribosomal_S5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013810">
        <property type="entry name" value="Ribosomal_S5_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13718">
        <property type="entry name" value="PTHR13718"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00333">
        <property type="entry name" value="Ribosomal_S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03719">
        <property type="entry name" value="Ribosomal_S5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01021">
        <property type="entry name" value="rpsE_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50881">
        <property type="entry name" value="S5_DSRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7 8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 7 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="S5 DRBM" evidence="9">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV57271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="128" mass="13248" checksum="0EF83C5F8D376632" modified="2019-10-16" version="1">MVVVGDGKGKVGWGYGKANEVPPSVQKATKQATRDMVAVPLISGSIPHQVWGKFGAAKVLLMPAGAGTGIIAGQAVRAVCESAGIHDILTKSYGTNNPVTLVKATIDALSKLRTRETIAALRGVELDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IW07</accession>
    <name>A0A518IW07_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">30S ribosomal protein S8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">rpsH</name>
        <name evidence="7" type="ORF">Mal33_32780</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uS8 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01302_B">
        <property type="entry name" value="Ribosomal_S8_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000630">
        <property type="entry name" value="Ribosomal_S8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035987">
        <property type="entry name" value="Ribosomal_S8_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11758">
        <property type="entry name" value="PTHR11758"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00410">
        <property type="entry name" value="Ribosomal_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56047">
        <property type="entry name" value="SSF56047"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00053">
        <property type="entry name" value="RIBOSOMAL_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV57274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="133" mass="15089" checksum="D9E0BD83108E0882" modified="2019-10-16" version="1">MMTDPIADMLTRIRNAVRVERPYVDIPLSRVKRGIADVLKREGFIWDWEEVDSEDLPIKLIRLELKYGPNGEQLIQSITRISKPGRRTYVRSRELRPILGGMGITIISTSKGVVSDREARRQGIGGEVLCEVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWA2</accession>
    <name>A0A518IWA2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Chaperone protein DnaK</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">dnaK_3</name>
        <name evidence="5" type="ORF">Mal33_33710</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="PTHR19375"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="SSF100920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00297">
        <property type="entry name" value="HSP70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00329">
        <property type="entry name" value="HSP70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01036">
        <property type="entry name" value="HSP70_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV57366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="516" mass="55504" checksum="7DA849222DDAB7B4" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWA8</accession>
    <name>A0A518IWA8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein translocase subunit SecE</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">secE</name>
        <name evidence="8" type="ORF">Mal33_33870</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the SecE/SEC61-gamma family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0065002">
        <property type="term" value="P:intracellular protein transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043952">
        <property type="term" value="P:protein transport by the Sec complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1030">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00422">
        <property type="entry name" value="SecE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005807">
        <property type="entry name" value="SecE_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038379">
        <property type="entry name" value="SecE_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001901">
        <property type="entry name" value="Translocase_SecE/Sec61-g"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33910">
        <property type="entry name" value="PTHR33910"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00584">
        <property type="entry name" value="SecE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00964">
        <property type="entry name" value="secE_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0811">Translocation</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="30"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="63"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="112"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV57382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="148" mass="16643" checksum="2EF2FA93BDE54CE0" modified="2019-10-16" version="1">MSTEVAGNSTAPLLPELFKGQVYKRNQGRLVRQMTCLAFWVIVALGCKSLYDSLQGFFDESSAALELAIPAITCLVGFWISFRLVNWPRFADFLIAVEAEMNKVSWPSKAELIRASIVVIFTIFFLAMSLFTFDIIWRAIFEFIGVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWF6</accession>
    <name>A0A518IWF6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_34290</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="385" mass="41979" checksum="A449FE95640FF931" modified="2019-10-16" version="1">MWLLGIAAVGQEPLILPQPSGPSAAETPQLLPSPSATLQQPEYPAGTVGEPIVLSDQSLTDIGYCDSGYCGSCSDDGSCVSCGTTNAHNDTFSGRLYSAFSAALCDGDPCYIPEWHLLESASFWVDSARTQNRTRVRWDYGIGMILPDRSEYFMAKIGGKGPSPQPGSASINRLDYHEMSFYTETARGKFSMFTVTPYRSLYMEQAGHGAGFGDIQIGTKSMLHDTRMLQVTLQTTTSIPTGRAKHGVGTGHVSLEPALLMGLALTDRDFLQAQAAEWIPLGGDSQYAGALLRWGVAWNRIVWQRDAKNLMTVNLDFVGWSFQDGAYTDPVLGTQSSSNGTYVYVGPGTRFLFCGKFEFGIGGLYALSEQHFAEHLMRTELTMRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWH9</accession>
    <name>A0A518IWH9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">YHS domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_34470</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.620.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012348">
        <property type="entry name" value="RNR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007029">
        <property type="entry name" value="YHS_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04945">
        <property type="entry name" value="YHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022223802" evidence="1">
        <location>
            <begin position="24"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="domain" description="YHS" evidence="2">
        <location>
            <begin position="42"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="153" mass="16191" checksum="4E51F70A893BE94C" modified="2019-10-16" version="1" precursor="true">MRSSNPVICVLLAVATLTSFASAADDTLATKKCKCPVAGTEFTVGDAAASTQYKDAKVYFCCPGCMKRFVADQKKYAAKANLQLFVTGQAKQVHCPFAGRDANPDQSVTVDNHKVAFCCGGCKGKAAAAEGDAQLEMLFGEKAFKTGFEVVKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWQ5</accession>
    <name>A0A518IWQ5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Y1_Tnp domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_35230</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002686">
        <property type="entry name" value="Transposase_17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036515">
        <property type="entry name" value="Transposase_17_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01797">
        <property type="entry name" value="Y1_Tnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143422">
        <property type="entry name" value="SSF143422"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Y1_Tnp" evidence="1">
        <location>
            <begin position="6"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="87" mass="10022" checksum="9C8C791EAD743ACA" modified="2019-10-16" version="1">MAEGLKPYPVQLLAYQSMPNHWHLVLRPTEAEGISKFLRWMTATHTMPYHAYDHTSGERIVYQGVIQELSGPRRRSLPCCLSARRLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXK7</accession>
    <name>A0A518IXK7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_38390</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="9"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="74" mass="8811" checksum="FFF9004C13977FDB" modified="2019-10-16" version="1">MSDLPRMSIKSLRELIAKTELTLDELKTELHHREEAAQDSEIDHLEDHMKHAEISLQSIRDFFVILINEYRSRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXT9</accession>
    <name>A0A518IXT9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_39120</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010869">
        <property type="entry name" value="DUF1501"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07394">
        <property type="entry name" value="DUF1501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="477" mass="52221" checksum="B8A66126C77A221E" modified="2019-10-16" version="1">MLKPSLYPCGKSRREFVWEMGAGFAGVALASLLGRDGISMGTAAAKEGQQRSQPRAKACIFLMMNGAPSQVDTFDFKPELEKYSGKQLPADKKFINSGGRKMGFLTPAWRPFRPGGESGLLVSDYFPNVRKHADKLCVIKSCHTDSHAHGSALVAMNTGKTLIGRPSLGSWCVYGMGSGNENLPGYVVMLDKRGGPISGQPNWSSGFMPATYAGTLFRPTGEPILDLKGPAHVTPAVQREQLDLLGQLNQQHLDLRPGSQDLADRIRSYELAYRMQSATPEAVDLSDESQQTLDAYGVGKQPTDEYGRNCLIARRLVERGVRFIQLYSGGGHLEETWDAHESIEKNHGQHAAEVDQPIAALLADLEQRGLLDDTLVVWGGEFGRMPFSEGQGAPGRNHNPYGFCMWMAGGGIRGGQSYGETDEFGFEAVQNKVHLHDLHATILHAMGQDHELLSWFHQGREETLTDVGGRVVHELFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXW8</accession>
    <name>A0A518IXW8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_39510</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="23"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="123" mass="12786" checksum="52FEF38B754A65B0" modified="2019-10-16" version="1">MVGAGMIAFAASVILARLTEQPLALVVACGLVCFTGAIASLFVTLTMSRASVDGIVAGAIAGMLVRVAMAMAGAIVFVSAGLGQRQVVGGWILYWYLTFLVVEVVWLVRQMSPTSSTQEAQSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXX1</accession>
    <name>A0A518IXX1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Lipoprotein-releasing system ATP-binding protein LolD</fullName>
            <ecNumber evidence="5">3.6.3.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">lolD_5</name>
        <name evidence="5" type="ORF">Mal33_39480</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.6.3.-" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="13"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="47"/>
            <end position="54"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV57932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="232" mass="25437" checksum="7FAE67D49F5EF7B4" modified="2019-10-16" version="1">MNQQAASDGGILIRAEDVTKNYPDGDVPALRGVSLDIRRGEYVVIMGPSGSGKSTLLNLLGALDTPTTGEIYFDGQPITSIHPLHKLRSDKIGFVFQSFHLIPTLTAVENVQIPMFVKGWSPSHRASLATELLESVGMSHRLNHFPQKLSVGERQRVALARALANDPVALLGDEPTGNLDSKTGNDVLDLFDRLHQQQNKTLVIITHSPEVAERADRVVHIRDGLIEREDAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXZ4</accession>
    <name>A0A518IXZ4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Phosphate import ATP-binding protein PstB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">pstB_2</name>
        <name evidence="7" type="ORF">Mal33_39730</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015415">
        <property type="term" value="F:ATPase-coupled phosphate ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:inorganic phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03260">
        <property type="entry name" value="ABC_PstB_phosphate_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015850">
        <property type="entry name" value="ABC_transpr_PstB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005670">
        <property type="entry name" value="Phosp_transpt1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43423">
        <property type="entry name" value="PTHR43423"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43423:SF3">
        <property type="entry name" value="PTHR43423:SF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00972">
        <property type="entry name" value="3a0107s01c2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="6">
        <location>
            <begin position="31"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="64"/>
            <end position="71"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV57957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="284" mass="31747" checksum="1AEFE7A0C3252C7C" modified="2019-10-16" version="1">MVQATSAVLSKNTKAGSAVNGRDNGAAENVVIDCKIDNLYYGKFRAVRDSHIPVQQGQITAFIGPSGCGKSTALRCLNRMNDLVRGFRFEGHVHFRGRDIYHRSVDPVAVRRYIGMVFQQPNPFAMSIYNNVAFGLRLNRVKGDVPERVEKALRGAALWDEVKDKLKNSGLSLSGGQQQRLCIARAIATEPEVLLMDEPCSALDPIATRRIEELMVELKKQYTIAVVTHNLQQAQRVADMTAFMYVDTSQGARTGYLVEYSKTEAMFADPQEEYTKQYIRGEFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IY05</accession>
    <name>A0A518IY05_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transposase for transposon Tn5</fullName>
            <ecNumber evidence="4">3.1.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">tnpA_8</name>
        <name evidence="5" type="synonym">tnpA_9</name>
        <name evidence="4" type="ORF">Mal33_39840</name>
        <name evidence="5" type="ORF">Mal33_45840</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.-.-" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.740.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038215">
        <property type="entry name" value="TN5-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003201">
        <property type="entry name" value="Transposase_Tn5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014737">
        <property type="entry name" value="Transposase_Tn5-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014735">
        <property type="entry name" value="Transposase_Tn5-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02281">
        <property type="entry name" value="Dimer_Tnp_Tn5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14706">
        <property type="entry name" value="Tnp_DNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tnp_DNA_bind" evidence="3">
        <location>
            <begin position="8"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="domain" description="Dimer_Tnp_Tn5" evidence="2">
        <location>
            <begin position="378"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="250"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV57968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV58561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="474" mass="53293" checksum="C62C9146D851CD3E" modified="2019-10-16" version="1">MQPTSIAYEFQDIQLGDKRLNDRAEALLASLAANPSASINEACSGWDETKAAYRLFDNPNVDPEAILGAHAEKTLQRIKAQDTVCIAQDTTELDYTAHPPEGVRNLDRLGRRGLYDHSHIAFTPEKLCLGVVGVKFYDRDKEALGTSKKREGLPLHTGEGQRWLDGYRKACEIAGKCPETQIVSLADREGDIYDIFVEADQHETPAQFVIRSQRKRSLPEKDPDGGPAAYKKMRAEIASAQPVAYREVQLPQTPERTKGSGNKQHPGREARTAKLEIRAKRMTLRAPHNKQSSMPPVEISVVWVSEIDGPGDGTEVDWLLLSSLPVDTIAQTLRIVDLYVARWPIEVFFRVFKTGCRVEEIQLEARDRLIRALMFYKVIAWRIMFVTFLGRECPELPCDVVFSEAEWKSVWKVVEKTAPPKQAPELSQFIPVLATLGGYNHREGDGPPGAEVIWRGTRRMLDFALCWQAFGPDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IY47</accession>
    <name>A0A518IY47_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Methylisocitrate lyase</fullName>
            <ecNumber evidence="3">4.1.3.30</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">prpB</name>
        <name evidence="4" type="ORF">Mal33_40180</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = pyruvate + succinate</text>
            <dbReference type="Rhea" id="RHEA:16809"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:57429"/>
            <dbReference type="EC" id="4.1.3.30"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Organic acid metabolism; propanoate degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.</text>
    </comment>
    <dbReference type="EC" id="4.1.3.30" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00946"/>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046421">
        <property type="term" value="F:methylisocitrate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019629">
        <property type="term" value="P:propionate catabolic process, 2-methylcitrate cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00377">
        <property type="entry name" value="ICL_PEPM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039556">
        <property type="entry name" value="ICL/PEPM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018523">
        <property type="entry name" value="Isocitrate_lyase_ph_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012695">
        <property type="entry name" value="PrpB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02317">
        <property type="entry name" value="prpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00161">
        <property type="entry name" value="ISOCITRATE_LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV58002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="287" mass="31251" checksum="30A09ABB8ABF029F" modified="2019-10-16" version="1">MSSSQTVTAGERLWSAVDHERPLQIAGAVNAISAMLAEQAGFRAIYLSGSGVASASHGLPDLGVTTLHDVLEDARRITSATELPLLVDADTGWGDSRMIGRATRELIRTGAAGLHLEDQIAEKRCGHRPGKRLVSTIEMQDRLKAALDGRTDDRFAIMARTDAVDVEGIDAAIDRAARYVETGAEMIFAEAVASLDDYKRFTAAVEVPVLANITEFGKTPLFTVDELRSAGVRLIIYPLTAFRCMNAAARNAYETLRRDGTQAELIATMQTREELYDVLDYHAQEPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IY87</accession>
    <name>A0A518IY87_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_40680</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008969">
        <property type="entry name" value="CarboxyPept-like_regulatory"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49464">
        <property type="entry name" value="SSF49464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="175" mass="18219" checksum="95E0AE05310F62EF" modified="2019-10-16" version="1">MVGRSKRSAITILNSRDFSLPMRTIFPIVLSVLTLVFSGCGPGSNEPPTVSVKGTVTLGGKPLEGANVYYFSEQYSSAGKTDAAGVYELTKGALPGENRVYISKISVPEGALADSDGGVDEGQLMAMAGDPALARSKSGPKEIVPVKYSDPSKTELTITVPESGTEAADFALEAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYA4</accession>
    <name>A0A518IYA4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peroxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_40840</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019791">
        <property type="entry name" value="Haem_peroxidase_animal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037120">
        <property type="entry name" value="Haem_peroxidase_sf_animal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03098">
        <property type="entry name" value="An_peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00457">
        <property type="entry name" value="ANPEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="SSF48113"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50292">
        <property type="entry name" value="PEROXIDASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="734" mass="79854" checksum="F7869D32977BC5AA" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ97</accession>
    <name>A0A518IZ97_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">2-dehydro-3-deoxygluconokinase</fullName>
            <ecNumber evidence="2">2.7.1.45</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">kdgK_3</name>
        <name evidence="2" type="ORF">Mal33_44280</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.1.45" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008673">
        <property type="term" value="F:2-dehydro-3-deoxygluconokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PfkB" evidence="1">
        <location>
            <begin position="33"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="361" mass="39263" checksum="EECAD95E1D9AE2AB" modified="2019-10-16" version="1">MSVLNIKSEADLDFLALGAVVHRLDPGTTVFRKAREFKVHVSGGEYNCAANLSDCFGLNTGVCTAMVNYGIGEMVQARIQETGVRPFYKHFEHDGVHGPNIATVYSDCGCGVRAPVVFYNRANEAGAMLKPGDFDWDKLFSGGVKWFHSGGIFAALSASTSELVIEAMKAARAKGTICSFDLNYRAKLWNKLGGLEKGQEMIAKIVENVDVLFGNEEDLQKGLGFSGPEVEEKKDSKLDPETFFQMIEKTVAKYPNIKMVATTLREVHTTNRHDWGAVLWIGGEKHVAPTCQLDVLDRIGGGDGFASGLIYGLLDGRPHEEALRLGWAHGALLTTFSGDISNAKLPEVEAFAQGGSARVQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZR9</accession>
    <name>A0A518IZR9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AAA_13 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_46060</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026866">
        <property type="entry name" value="CR006_AAA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13166">
        <property type="entry name" value="AAA_13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_13" evidence="1">
        <location>
            <begin position="371"/>
            <end position="693"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="848" mass="94828" checksum="91C5D4F1832BF029" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZT8</accession>
    <name>A0A518IZT8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Y1_Tnp domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_46280</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002686">
        <property type="entry name" value="Transposase_17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036515">
        <property type="entry name" value="Transposase_17_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM01321">
        <property type="entry name" value="Y1_Tnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143422">
        <property type="entry name" value="SSF143422"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Y1_Tnp" evidence="1">
        <location>
            <begin position="13"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="358" mass="40457" checksum="40504705F698C1F4" modified="2019-10-16" version="1">MARQTRGEVIDPAEVQIVHCIERCVRRAYLCGHDPLTGKSFEHRRGWIRQRLEFLASCFAIDCLTFAIMNNHLHLVLRSRPDVVAGLSDEEIARRWLRLFPNRRNDDGSPADPSDADIEMIVGTPKILAQRRRRLSDISWWMRCTAENIARRSNAEDDVTGHFWEGRFKAQILLDEVSVLACAAYVDLNPIRAAMTELLETSEFTGAKERIDDIARLTPASRTYLHDWERASQQQISGWMSPLEIDERDDPTGPDIERSHRRASCKGFLSISLAKYLELVDWTGRQICNGAGASIPADLAPILSRFGLDSCAWCNLIKRYGRVFKRAAGTSESLAQEAKRRGQAWLQAPGNPLTVCAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZZ4</accession>
    <name>A0A518IZZ4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphodiesterase YaeI</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_46830</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="Metallophos" evidence="2">
        <location>
            <begin position="155"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="380" mass="42997" checksum="57561C9772379481" modified="2019-10-16" version="1">MFLQIVHWMLILLGHFGLHLTFYNRINATGLPRWQIKLVERTIAVECFLFPLLLLWYPSPASLPMWLQVYSWICLTAIVVLGIPWLIYRPLFGIQWLPIERQVTHVAVDQVLPESPIGSLRCRINAAIPMNQITELAIEQKHLPVAGLPQQLEGLRLAHFSDIHLTGDMLPSFYRYVSDQLMQWQPEIVCVTGDIVDKPHCIPWLSECFGKITAPGGCYFILGNHDTRVADPNQVREAMQEMGWTDLGGIAKRIPLRDTEIAIAGNELPWFGPAPAFPESSEPEFRVLLSHSPDQIAWARRNAVHLMLAGHTHGGHGRLPLIGPLLSPSRYGSRFASGEFDLPPTTMHVTRGLFGTHMQRFRCPPELSLLTLHQRDRTSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J019</accession>
    <name>A0A518J019_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Cytochrome c domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Mal33_47110</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002327">
        <property type="entry name" value="Cyt_c_1A/1B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013427">
        <property type="entry name" value="Haem-bd_dom_put"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11961">
        <property type="entry name" value="PTHR11961"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00034">
        <property type="entry name" value="Cytochrom_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02603">
        <property type="entry name" value="CxxCH_TIGR02603"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="3 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Cytochrome c" evidence="6">
        <location>
            <begin position="234"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV58687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="371" mass="39636" checksum="9EDD7F5EFFE91A89" modified="2019-10-16" version="1">MFRIPLSIVVCFAMGAIAFGQEGNSLSPRDKLIVETVLRIKDFKIESSAPAKAALLRYLRSQPGTEQYFELIERFGLTDVAGELTEFAIAHADETAGVRAAELLFKLDSQKLLIDAISAEASEHAVAAVSLIGRVGGTKTQEILMPLVAASDKSAELRAAAVAGIARRTDGQRALLKIVADGKLPADLNFAAANALFGSDDKSIVAEAAKYLQLPATADSQPLPPISELIQKQGDPVAGAIVFRKSGTCINCHKVKGEGKEVGPDLSEIGSKLSREAMYVAVLNPSAAVSHNFETYSLLTIDGDATTGLLVSETDAAVTLRNAEGIDKTVARDDIELFQKQAKSLMPQDLQRLMTVPQLIDLIEYTLTLTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J095</accession>
    <name>A0A518J095_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Tellurite resistance protein TehB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_47840</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044995">
        <property type="entry name" value="TMT/HOL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008854">
        <property type="entry name" value="TPMT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32183">
        <property type="entry name" value="PTHR32183"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05724">
        <property type="entry name" value="TPMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51585">
        <property type="entry name" value="SAM_MT_TPMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV58759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="215" mass="23791" checksum="2EE304CA25C7E760" modified="2019-10-16" version="1" precursor="true">MDANSTSRPACKVCCRDQTRLSSTDWQARYDAGKTGWDRGEPNPMLGRWMASGELQPGKILVPGCGRGHEVIALAEAGFDVTAIDFADAAVQSLSDELKRRDLKANVVQKDVFAYCPSRSFDAVYEQTSLCAIHPSQWATYQQLLACWLRSGGQLFALFMQSGTAGGPPYSCELDTMHKLFAKPTWHWSDSKTRVEHPTGMHEIACVLTRKETNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0C8</accession>
    <name>A0A518J0C8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Sialidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_48210</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011040">
        <property type="entry name" value="Sialidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036278">
        <property type="entry name" value="Sialidase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13088">
        <property type="entry name" value="BNR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50939">
        <property type="entry name" value="SSF50939"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021791303" description="Sialidase domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="932"/>
        </location>
    </feature>
    <feature type="domain" description="Sialidase" evidence="2">
        <location>
            <begin position="596"/>
            <end position="884"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="932" mass="103916" checksum="866FE8C0846061B8" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0S6</accession>
    <name>A0A518J0S6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_49570</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="192" mass="21971" checksum="0B83EBE9B1A9DABD" modified="2019-10-16" version="1">MPEPDPQRIRSFETPAAYGAWLQANHDSEPELWLKLFKKATGIPSIDWTEAVIESLCWGWIDGIKKSLDDKAYLQRVTPRRPRSHWSKRNCEHVERLIAEGRMQEPGLAHVHAAQADGRWEAAYSPASEMVMHDDFLAALRGNPKANQAFEKLSKSSLYLIGFHLQTAKRPETLQKRIVKYVGMLEQGKPIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0U8</accession>
    <name>A0A518J0U8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">6-phosphogluconate dehydrogenase, decarboxylating</fullName>
            <ecNumber evidence="3 7">1.1.1.44</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">gndA</name>
        <name evidence="9" type="ORF">Mal33_49500</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 7">
            <text>6-phospho-D-gluconate + NADP(+) = CO2 + D-ribulose 5-phosphate + NADPH</text>
            <dbReference type="Rhea" id="RHEA:10116"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58759"/>
            <dbReference type="EC" id="1.1.1.44"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 7">Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 3/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3 7">Belongs to the 6-phosphogluconate dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.44" evidence="3 7"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00410"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004616">
        <property type="term" value="F:phosphogluconate dehydrogenase (decarboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019521">
        <property type="term" value="P:D-gluconate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016054">
        <property type="term" value="P:organic acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006114">
        <property type="entry name" value="6PGDH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006113">
        <property type="entry name" value="6PGDH_Gnd/GntZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006115">
        <property type="entry name" value="6PGDH_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006183">
        <property type="entry name" value="Pgluconate_DH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11811">
        <property type="entry name" value="PTHR11811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00393">
        <property type="entry name" value="6PGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03446">
        <property type="entry name" value="NAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000109">
        <property type="entry name" value="6PGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00076">
        <property type="entry name" value="6PGDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01350">
        <property type="entry name" value="6PGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00873">
        <property type="entry name" value="gnd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0311">Gluconate utilization</keyword>
    <keyword evidence="3 7" id="KW-0521">NADP</keyword>
    <keyword evidence="3 7 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3 7" id="KW-0570">Pentose shunt</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="6PGD" evidence="8">
        <location>
            <begin position="183"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="130"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="190"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="187"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="194"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="11"/>
            <end position="16"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="34"/>
            <end position="36"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="76"/>
            <end position="78"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 6">
        <location>
            <position position="104"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="265"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="292"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="461"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="467"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR000109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000109-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000109-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000109-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV58925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="491" mass="53883" checksum="B86C4B1423F5680E" modified="2019-10-16" version="1">MSGDCDFGLIGLAVMGENLALNVESRGYKVAVYNRTTDKVDALIEGRAAGKNFVGCHSIEEFVKSCARPRKLMMLVKAGPAVDAIIEQLTPFLEPGDIIIDGGNTHYADTERRTKEVEAKGFHFIGTGVSGGEEGALKGPSLMPGGSKDAWPMVKEMFQAISAKVGPNNDIPCCDWVGPRGAGHYVKMVHNGIEYGDMQLICEAYQLLKDVGGLTNDELYDVFDEWNKGELQSYLIEITRDIFSVKDGDTNDHLVDRILDVAGAKGTGKWMSQLALDLGVPSTLVTSAVFARGISAQKEARVRASSILPGPAEGDNPKLAAAVAELAGDRATFIEMVRQGLYASKIVSYAQGFVQLQAASQEHDWDLDYGQCALLWRGGCIIRAQFLDRIKEAFDDQPNLENLMLYPYFKDAMATAQPHFRAVVMAATQLGVPVPAFSTALAYYDSYRRDRLPANLLQAQRDYFGAHTYKRTDKDGVYHTEWLDLRKQPTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0V2</accession>
    <name>A0A518J0V2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Monooxygenase</fullName>
            <ecNumber evidence="2">1.-.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_49950</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.-.-.-" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007138">
        <property type="entry name" value="ABM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03992">
        <property type="entry name" value="ABM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51725">
        <property type="entry name" value="ABM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABM" evidence="1">
        <location>
            <begin position="4"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="96" mass="11119" checksum="629F6D3754D4BB7C" modified="2019-10-16" version="1">MANLTIVAHIHAKADQIDFVKSELEKMVAPTRAEKGCVQYDLHQDHDHPTHFMFFENWESRELWQDHSNSQHVQAYRAASEGAVESFTLHEMTQIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0V5</accession>
    <name>A0A518J0V5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative transcriptional regulatory protein pdtaR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">pdtaR_2</name>
        <name evidence="3" type="ORF">Mal33_49890</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="6"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="121" mass="13178" checksum="947C2A4E7E4965A9" modified="2019-10-16" version="1">MKRSLRIVIADDEADIRQGFRRLLCKLGCEVVGEAENGRDLIALCAAERPDLVITDVRMPEMSGIEAAKVIAKANSIPVIVVSSYERPDDEDCAFIADFLLKPICITELRAAINKACDGAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0Y9</accession>
    <name>A0A518J0Y9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_50360</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="121" mass="13584" checksum="0EE8A23097E5A638" modified="2019-10-16" version="1">MLACVKIRQAVTDFLVGLRMAHLLYGAFLDQAMKRSANGLDVWAAIRIGGFKKTLNIVNSHDPVAWDECCHEVDKLLFPFGFWPDCYRLPDKPLFHRCDFGDGLAVLCSDFVKLAVASFFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J133</accession>
    <name>A0A518J133_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_50720</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="178" mass="19446" checksum="7FF26E2CC7024FF0" modified="2019-10-16" version="1">MFNTTAPDYPASVIGQFHRISTVRLDAFSGMQITNGPYGAISEPGPSDGTTHASADKEIPESEFISAIAWVLKHQTEIRKDFFAPFVDEYEEMRDILICDLGDEKAAKLVPKISSPEDLSPLCGLVALHIRGLNDTGEARFGIELGCNWEDEHGAGVRFNGLQIEEAGHADVSFLFCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J175</accession>
    <name>A0A518J175_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Type II secretion system protein G</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">xcpT_16</name>
        <name evidence="3" type="ORF">Mal33_51070</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011453">
        <property type="entry name" value="DUF1559"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07596">
        <property type="entry name" value="SBP_bac_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="194"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV59082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="366" mass="38984" checksum="E94456ECA8281AF1" modified="2019-10-16" version="1">MPTLPPRQTSPSKTLGFTLVELLVVIAIIGVLVGLLLPAVQSAREAARRMQCKNNVKQIALGMSMHEHTFGHYPYSRTGSLWRILSFVEQEALANVFNDAKHPNYNDPASSEYRWGYNAQIGTDWSNKADLVVAAGTSLSVFQCPSATGTRAVESSGVALGVSDYTTPRVPALRPVGHPLYYQSGEPQMQFSTAMTPASGSRNRNPLNKGGKARDITDGLSNTMMYYECVGSPELFVRGTVAAPTGGASLAWAGSGDGVKMRAYASDNLTADTSDTARGISSSGDPTVPDNATDCSAGAAWEAAIDTCGSFRVMNHTNKSQPYSFHPGIVNVGLCDGSARSISETIDIGVFLNLMLRNDGQVLGEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1Q1</accession>
    <name>A0A518J1Q1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_52880</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="64" mass="7480" checksum="503F37020A5DA585" modified="2019-10-16" version="1">MNRNVPEMEIFGSRGLFLARSLLFFTFVRVTAKHVSDPNETRDDIRRAIWRALSDNELTKILTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1Y3</accession>
    <name>A0A518J1Y3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acetylxylan esterase</fullName>
            <ecNumber evidence="4">3.1.1.72</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">axeA1_3</name>
        <name evidence="4" type="ORF">Mal33_53770</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.1.72" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046555">
        <property type="term" value="F:acetylxylan esterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022135185" evidence="2">
        <location>
            <begin position="23"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="Abhydrolase_3" evidence="3">
        <location>
            <begin position="90"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV59349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="298" mass="32649" checksum="141F4656ED87BE9F" modified="2019-10-16" version="1" precursor="true">MKLLASLVGCVFVICNIGSGTAAELETVRLWPQEAPGETSSVGPERQLPTRPQEEPNPIIRLTDIATPILTFYPAPEPASTGTTVIVCPGGGYNILAYNHEGTEICEWLNSIGVSAVLLKYRVPRRDPDAPHAIPLKDAQRAVRLVRSKAKDWKINPDRIGMLGFSAGGHLAVMAGTHFRDTTYEAIDEADKLSCRPDFLIPIYPAYLVDTKNKTQLDPQVTVDSETPPTFVAISYDDADRAIGAALLLILMKQNNVPCELHVYHKGGHGYGMRPSKNPVAQWPQRCQDWMVSLGLLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1Z3</accession>
    <name>A0A518J1Z3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CsbD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_53880</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0337 (CsbD) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008462">
        <property type="entry name" value="CsbD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036629">
        <property type="entry name" value="YjbJ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05532">
        <property type="entry name" value="CsbD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69047">
        <property type="entry name" value="SSF69047"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="124"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="CsbD" evidence="3">
        <location>
            <begin position="6"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV59360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="145" mass="15951" checksum="0EB4FBB28AB640BD" modified="2019-10-16" version="1">MITREELKGQWNEVKGRLQENWGQLTDDDLSRARGSAEQLVGVVQQKTGASRREVEEFLSRAVGEGSRIGDQVSQAAQQYADVASQYAADAGEYVKENYRRASELSGDYSERLAHTVRTRPAESLAIAFGLGIAAGAIVFMKGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IM02</accession>
    <name>A0A518IM02_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_00360</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="289" mass="31548" checksum="5925969446C5982D" modified="2019-10-16" version="1">MPESTVLSSGGLQNLEAPNQALVHALAAEAAPVTAADLCRKLPKIDQNDPQTIQTRLESLVQQQVLHRFAPYRGKADRFWNRSLDQYATLVITSEAEKQVGTKSDLSSRCRARLKDMSVKQLGDFINQLAASGQLHVGRFLGSQALRYSARPIGPQAMLENAIAQIAKRCSISPDEVRASIVPTDRTTPGATTPIEPNVSDETLVMQMIGQMSPNPSTAGAIVSIAELRRAMEFKLVGESFDAAIRQLEAHAQVDLTTHPDPGSLSPEDREARKLRGDGKVYDMLVVRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IM33</accession>
    <name>A0A518IM33_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HEAT repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_00960</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="170" mass="17609" checksum="93B0FE0763FD07A1" modified="2019-10-16" version="1">MTDQPRQDPSNLEHSDPAIRRQTLQSIIDESPRLADWTIPLLRAACDPHASVSELAIATLEDMGAPDASQVADIVAFAQRPADSETVYWATTLIGRIGPAAADAVPTLAGVLANSSFLHVREKAAWALGQIGPAAVGASAVLQSAAEQGPPRLQRLATKALAAMAGSAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IM63</accession>
    <name>A0A518IM63_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="14 15">Dihydroxy-acid dehydratase</fullName>
            <shortName evidence="15">DAD</shortName>
            <ecNumber evidence="14 15">4.2.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">ilvD_1</name>
        <name evidence="15" type="synonym">ilvD</name>
        <name evidence="16" type="ORF">Mal33_01180</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>(2R)-2,3-dihydroxy-3-methylbutanoate = 3-methyl-2-oxobutanoate + H2O</text>
            <dbReference type="Rhea" id="RHEA:24809"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:49072"/>
            <dbReference type="EC" id="4.2.1.9"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:24810"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>(2R,3R)-2,3-dihydroxy-3-methylpentanoate = (S)-3-methyl-2-oxopentanoate + H2O</text>
            <dbReference type="Rhea" id="RHEA:27694"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:35146"/>
            <dbReference type="ChEBI" id="CHEBI:49258"/>
            <dbReference type="EC" id="4.2.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
        <text evidence="15">Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 15">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="13 15">Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 3/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="12 15">Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 3/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="15">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the IlvD/Edd family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.9" evidence="14 15"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00047">
        <property type="reaction ID" value="UER00057"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00049">
        <property type="reaction ID" value="UER00061"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004160">
        <property type="term" value="F:dihydroxy-acid dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00012">
        <property type="entry name" value="IlvD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042096">
        <property type="entry name" value="Dihydro-acid_dehy_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004404">
        <property type="entry name" value="DihydroxyA_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000581">
        <property type="entry name" value="DiOHA_6PGluconate_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020558">
        <property type="entry name" value="DiOHA_6PGluconate_deHydtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037237">
        <property type="entry name" value="IlvD/EDD_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00920">
        <property type="entry name" value="ILVD_EDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143975">
        <property type="entry name" value="SSF143975"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00110">
        <property type="entry name" value="ilvD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00886">
        <property type="entry name" value="ILVD_EDD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00887">
        <property type="entry name" value="ILVD_EDD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 15" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="3 15" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10 15" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="7 15" id="KW-0408">Iron</keyword>
    <keyword evidence="8 15" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="9 15 16" id="KW-0456">Lyase</keyword>
    <keyword evidence="6 15" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="15">
        <location>
            <position position="474"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="126"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" description="via carbamate group" evidence="15">
        <location>
            <position position="127"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="448"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-carboxylysine" evidence="15">
        <location>
            <position position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00029304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00029436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00029437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00029490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="QDV54171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="559" mass="59573" checksum="898DF9549D602F25" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMD6</accession>
    <name>A0A518IMD6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Probable molybdenum cofactor guanylyltransferase</fullName>
            <shortName evidence="4">MoCo guanylyltransferase</shortName>
            <ecNumber evidence="4">2.7.7.77</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">GTP:molybdopterin guanylyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Mo-MPT guanylyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Molybdopterin guanylyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Molybdopterin-guanine dinucleotide synthase</fullName>
            <shortName evidence="4">MGD synthase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4 6" type="primary">mobA</name>
        <name evidence="6" type="ORF">Mal33_02100</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>GTP + H(+) + Mo-molybdopterin = diphosphate + Mo-molybdopterin guanine dinucleotide</text>
            <dbReference type="Rhea" id="RHEA:34243"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
            <dbReference type="ChEBI" id="CHEBI:71310"/>
            <dbReference type="EC" id="2.7.7.77"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="4">The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the MobA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.77" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061603">
        <property type="term" value="F:molybdenum cofactor guanylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02503">
        <property type="entry name" value="MobA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00316">
        <property type="entry name" value="MobA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025877">
        <property type="entry name" value="MobA-like_NTP_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013482">
        <property type="entry name" value="Molybde_CF_guanTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12804">
        <property type="entry name" value="NTP_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 4" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="1 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transf_3" evidence="5">
        <location>
            <begin position="16"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="19"/>
            <end position="21"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="76"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF12804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV54260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="212" mass="22817" checksum="DEFC905C0737FBF5" modified="2019-10-16" version="1">MTIHSSQTTQRLSLLGAILAGGRSSRMGSSKAMLPMPTGTTLLEHVAACLNPYCRSIVVSVAPSQQLTTSLPTVPDTDASQGPASGIASVLQLANQQGFAAAMIVSVDLPALTAIDLAPLIAAWEADPDRITATTADGKFPEPLVAIYPATYLEQLTTVACGADRSIMRWLRRTPHQTITIRREAIQDVDTPEQWNAYHDREVRKNARPSDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IML4</accession>
    <name>A0A518IML4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sigma-70, region 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_02790</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sigma70_r4_2" evidence="1">
        <location>
            <begin position="141"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="199" mass="22536" checksum="BA89C0E3B6277B0E" modified="2019-10-16" version="1">MKQKPGSPHISRFAAVAVTALICSSGETASAHSAPASESNAIQQIERYCSKSWQTAHMPRDEWNDSTQQVLAELLERIPRERLTAAIGASASEERRELNRSIWRIVKRWVRRQRHAPLDDFDTPGVVDDQSSRVDDQIEQVLRVASTQLSDQQRRIIELLKEGLTVAEIAGRMDLTPSRISNEKHRAIKQIRRYLCDAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMS6</accession>
    <name>A0A518IMS6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_03450</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011444">
        <property type="entry name" value="DUF1549"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022655">
        <property type="entry name" value="DUF1553"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008964">
        <property type="entry name" value="Invasin/intimin_cell_adhesion"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07583">
        <property type="entry name" value="PSCyt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07587">
        <property type="entry name" value="PSD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49373">
        <property type="entry name" value="SSF49373"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021800151" evidence="2">
        <location>
            <begin position="37"/>
            <end position="936"/>
        </location>
    </feature>
    <feature type="domain" description="PSCyt2" evidence="3">
        <location>
            <begin position="273"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="domain" description="PSD1" evidence="4">
        <location>
            <begin position="581"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="811"/>
            <end position="856"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV54391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="936" mass="104915" checksum="E4CBC100B95DD005" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMY2</accession>
    <name>A0A518IMY2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_03970</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011447">
        <property type="entry name" value="DUF1552"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07586">
        <property type="entry name" value="HXXSHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="454" mass="50517" checksum="4E7CA9250DC1F7B4" modified="2019-10-16" version="1">MSNPKNRAGSKTNRADRAVSRRTLLRGTGVAMALPWLESIPVWGSEKLTDDQVTASPQRFAALFMGCGINRDHWWAKGSGTEMELGKSLAPMEPIKHKMNFITGLYNENANGVGIHPGQTGNILSGASLKKGSELRGDISMDQVLANHFAEETVAPSLVLGCEQPTTGYHETNFSMAYSSHISWQNATSPVPMEVYPSLAFDSLFDNHGSRRMESILDRVREETASLNRKISQSDRTKLDEYLSSVREVEKRAEAMRTVHAKATERAHHRGQPIAAMKRPDDGLPEDIREHMQLMCDIIAIGFQTDKSRVATLLLNRDLSGLFYPFLDVTKTHHSASHDDRSDEYERISRYYCSQYAYLASKLDAMPEGDGTVLDHSCLLFISSMWSGSSHDSTKLPVLLTGGMSGRMETGRVLDYLDKGDDNRKLCGMYLTIMDRMGVKLDRFGDAENQLAGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IN07</accession>
    <name>A0A518IN07_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Tyrosine recombinase XerC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">xerD_1</name>
        <name evidence="10" type="synonym">xerC</name>
        <name evidence="15" type="ORF">Mal33_04310</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the 'phage' integrase family. XerC subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the 'phage' integrase family. XerD subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009037">
        <property type="term" value="F:tyrosine-based site-specific recombinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01808">
        <property type="entry name" value="Recomb_XerC_XerD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044068">
        <property type="entry name" value="CB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004107">
        <property type="entry name" value="Integrase_SAM-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011932">
        <property type="entry name" value="Recomb_XerD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023009">
        <property type="entry name" value="Tyrosine_recombinase_XerC/XerD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02899">
        <property type="entry name" value="Phage_int_SAM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02225">
        <property type="entry name" value="recomb_XerD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51900">
        <property type="entry name" value="CB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4 10" id="KW-0132">Cell division</keyword>
    <keyword evidence="5 10" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="3 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 10" id="KW-0229">DNA integration</keyword>
    <keyword evidence="8 10" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="7 10 11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core-binding (CB)" evidence="14">
        <location>
            <begin position="21"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="Tyr recombinase" evidence="13">
        <location>
            <begin position="125"/>
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        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
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        <location>
            <position position="165"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="189"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="262"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="265"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="288"/>
        </location>
    </feature>
    <feature type="active site" description="O-(3'-phospho-DNA)-tyrosine intermediate" evidence="10">
        <location>
            <position position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="HAMAP-Rule" id="MF_01808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="QDV54477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="316" mass="36014" checksum="B8014DD744AD0FBC" modified="2019-10-16" version="1">MARPTKLQQLKSRGPAKKSDGRSQSYCADFIVYLRNECHLADNSIKAYSRDLKRFLDWLEDRSIPRLKIADLSQYVSWLCQRSLAPASVARHVVALRTFYKYLQLEGVVLDNPAELLTTQKMWQRMPGVLSPAQVDGLLAAPRRSDSYWQRDRALLEVLYATGCRASEVCGLRLQNVNLKQKHLKCEGKGGKQRMVPLGVRSIESIQMYIDQLRVRLVALAATTPEHLFLSRSGQALDRVQVWRLVKRYAQRAGISDDISPHSLRHSFATHLLAGGAGLRQVQEMLGHANIQTTQIYTHVDHSRLQKVHREFHPRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IN14</accession>
    <name>A0A518IN14_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">O-Antigen ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_04410</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007016">
        <property type="entry name" value="O-antigen_ligase-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04932">
        <property type="entry name" value="Wzy_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0436">Ligase</keyword>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="35"/>
            <end position="56"/>
        </location>
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            <end position="86"/>
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            <end position="116"/>
        </location>
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        </location>
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            <begin position="497"/>
            <end position="517"/>
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    <feature type="transmembrane region" description="Helical" evidence="4">
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            <begin position="523"/>
            <end position="554"/>
        </location>
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        <location>
            <begin position="1"/>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV54487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="793" mass="85154" checksum="1FCB4E55991CDF81" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IN46</accession>
    <name>A0A518IN46_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Multidrug resistance protein MdtA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">mdtA_1</name>
        <name evidence="5" type="ORF">Mal33_04600</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="30"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="domain" description="HlyD_D23" evidence="4">
        <location>
            <begin position="87"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="138"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV54506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="418" mass="45854" checksum="5E2675434D0E62F7" modified="2019-10-16" version="1">MNEHTLTIDADTIDDIGDPAPVPNVPAWKLAFLIVALTGMIVAAFFVGWLPKTHRQQTLVETVQRQKEMLPIVEIVLPKPALETVEVTFPGEIEALEETVIYARTSGYLKRWHVDIGDTVQQGQLLAEIDTPEVDQQLQQALANVEQLKARREVAETKLGLTRYTLTRLDELLQSQAASRQEYDESQAEFAVAEHQVKVADADIAAGMAELQRIKELQSFAKVYAPFAGTITERSIDLGQLVTAGSGQAQSLFRLVSTDRVRGVVHVPQIYAFNIEPGEQAQLLVREMADRTFVGQVARTARSLDLQTRTMRIEIEFDNSDGQLLPGAYVQVRLPLRRPNPPMLIPASALIFNASGSQIATVNAENLVELRAVDVDADYGNVLGIATGIESTDRIVVNPGERLVDGMSVTIAEPDAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INH5</accession>
    <name>A0A518INH5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_05910</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010869">
        <property type="entry name" value="DUF1501"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07394">
        <property type="entry name" value="DUF1501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="493" mass="54043" checksum="36E25AA36298C76B" modified="2019-10-16" version="1">MNRFPTTRREFLSRASGGFAATALAGLCGDLQAASDDPLAPRSGHHAAKAERVIFLYSTGGTSHVDSFNHRPQLIADHGKSITASRWLNKSGDFKRFLIKPRYAFKQYGESGTWVSELFPHLGSVIDDVCVLNAMHCESDGHDKATLAAHTGSAQFARPSAGSWVSYGLGTVNQNLPSFMVLAPAAPYAGAQTWASDFLPACHQGTHVIPGSEPLPNIRPQDTDDALQQMELALRRNLNQTHLQQRAADQALDARIRSFETAFGMQREAPEAFDLSDETQATLELYGTERDATAGFGWQCLVARRLAERGVRFLELIDVGSNSNWDSHGNMGDHQRLAKAIDKPIAGLLTDLKQRGMLESTLVVWTTEFGRTPFHQNANHAGREHHNLCFSSWMAGGGVKGGIVHGHSDEYGIRTAEDAVHTHDLHATMLHLLGLDHERLTYRHAGRDYRLTDVHGRVVQEILTYVAVSSFCQSCKHCEQALGGTTATASVWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INI4</accession>
    <name>A0A518INI4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_06010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="83" mass="9850" checksum="1153081D85F7EE25" modified="2019-10-16" version="1">MNPAFLNDIDSRMRKDWTSFVEVWQQTKDQWRDGKCRQFEQEDLQPLPGVMSQTSAAIAEFRDFAARVSQELRDEESENDFFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INL8</accession>
    <name>A0A518INL8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">dCTP deaminase, dUMP-forming</fullName>
            <ecNumber evidence="3">3.5.4.30</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Bifunctional dCTP deaminase:dUTPase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">DCD-DUT</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 5" type="primary">dcd</name>
        <name evidence="5" type="ORF">Mal33_06360</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>dCTP + 2 H2O = diphosphate + dUMP + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:19205"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61481"/>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
            <dbReference type="EC" id="3.5.4.30"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homotrimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the dCTP deaminase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.30" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00610">
        <property type="reaction ID" value="UER00667"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033973">
        <property type="term" value="F:dCTP deaminase (dUMP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008829">
        <property type="term" value="F:dCTP deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006226">
        <property type="term" value="P:dUMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006229">
        <property type="term" value="P:dUTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07557">
        <property type="entry name" value="trimeric_dUTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00146">
        <property type="entry name" value="dCTP_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011962">
        <property type="entry name" value="dCTP_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029054">
        <property type="entry name" value="dUTPase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036157">
        <property type="entry name" value="dUTPase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033704">
        <property type="entry name" value="dUTPase_trimeric"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00692">
        <property type="entry name" value="dUTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51283">
        <property type="entry name" value="SSF51283"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02274">
        <property type="entry name" value="dCTP_deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 3" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="dUTPase" evidence="4">
        <location>
            <begin position="83"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="3">
        <location>
            <position position="121"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="93"/>
            <end position="98"/>
        </location>
        <ligand>
            <name>dCTP</name>
            <dbReference type="ChEBI" id="CHEBI:61481"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>dCTP</name>
            <dbReference type="ChEBI" id="CHEBI:61481"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="119"/>
            <end position="121"/>
        </location>
        <ligand>
            <name>dCTP</name>
            <dbReference type="ChEBI" id="CHEBI:61481"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="138"/>
        </location>
        <ligand>
            <name>dCTP</name>
            <dbReference type="ChEBI" id="CHEBI:61481"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="151"/>
        </location>
        <ligand>
            <name>dCTP</name>
            <dbReference type="ChEBI" id="CHEBI:61481"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="154"/>
        </location>
        <ligand>
            <name>dCTP</name>
            <dbReference type="ChEBI" id="CHEBI:61481"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for bifunctional activity" evidence="3">
        <location>
            <begin position="108"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV54680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="192" mass="21986" checksum="83C6B0EEE0367FCE" modified="2019-10-16" version="1">MILSGEEIRSRIGKQIVIEPFDDDKLNPNSCNLSLHDELLVYEEVVLDIRQPNRYRRLEIPAYGFVLQPGCLYLGRTCEWTETRGLVPMIEGRSSLGRLGLFVHVTTGFGDAGFCGYWTLEICTVQPIRIYPGIDICQIMYHEICGDVEEYCSKYQNSRDIQPSMMYRELGGSESDQQLELDFESLVREAIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INT1</accession>
    <name>A0A518INT1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_07130</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="66" mass="7011" checksum="538CC81DC78375CD" modified="2019-10-16" version="1">MKQQVLSLLLIASTGGFVGSGCAPRVAPGDPEVPRKTVYTRAEIDALKAEGVSDRELKNMGIKVIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INV4</accession>
    <name>A0A518INV4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Polysaccharide biosynthesis/export protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_07390</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015159">
        <property type="term" value="F:polysaccharide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003715">
        <property type="entry name" value="Poly_export"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02563">
        <property type="entry name" value="Poly_export"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="194"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="471" mass="50215" checksum="A6CDADCA11CC66B6" modified="2019-10-16" version="1">MCVLTKNRSSIVLSRWNWLAATSLLVLSATGCTSIMSPISGTPVGHLPPEMRGQSRNNLVPVPLSILRQQAPPHYLLDEGDILGIYIEGIMPPKAGADQTEAAPPVHFPEAGSDLPPAVGYPIPIRDDGTLPLPLVDPIQVRGMTLTEVEAAIRKAYVVDRNILKEGRDRILVSLMRERTYRVIVIREDEDDSLALPGGGRGGSGSQGSIVGGASRSGSGYTLDLPAYKNDVMHALAQTGGLPGLNAKNEVKILKANRVGQLDANGTPMMVMPGMMGADGMVAGDCYGGCMPHDPCYSGFNPNEDYDPTAIRIPLRVAPGQMPHLQPADIILEEGDIVVVEARDTEVFYTGGLLPGGQFPIPRDYDLDVVGAMAIAGQGLGSSGPSKGGGSLLGGGFAGASPTQLYVMRTTPYGDQFNISVDLNKALNDKSERLMIQPGDTLILRYKPCEELVNFSLVTFFTYGIRELFSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP01</accession>
    <name>A0A518IP01_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 12">Aspartate-semialdehyde dehydrogenase</fullName>
            <shortName evidence="12">ASA dehydrogenase</shortName>
            <shortName evidence="12">ASADH</shortName>
            <ecNumber evidence="7 12">1.2.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Aspartate-beta-semialdehyde dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12 14" type="primary">asd</name>
        <name evidence="14" type="ORF">Mal33_07840</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>L-aspartate 4-semialdehyde + NADP(+) + phosphate = 4-phospho-L-aspartate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:24284"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57535"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:537519"/>
            <dbReference type="EC" id="1.2.1.11"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 12">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 2/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 12">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 2/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 12">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 2/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6 12">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 12">Belongs to the aspartate-semialdehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.11" evidence="7 12"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00016"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00050">
        <property type="reaction ID" value="UER00463"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00051">
        <property type="reaction ID" value="UER00464"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004073">
        <property type="term" value="F:aspartate-semialdehyde dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071266">
        <property type="term" value="P:'de novo' L-methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019877">
        <property type="term" value="P:diaminopimelate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02121">
        <property type="entry name" value="ASADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012080">
        <property type="entry name" value="Asp_semialdehyde_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005986">
        <property type="entry name" value="Asp_semialdehyde_DH_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000534">
        <property type="entry name" value="Semialdehyde_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012280">
        <property type="entry name" value="Semialdhyde_DH_dimer_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01118">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02774">
        <property type="entry name" value="Semialdhyde_dhC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00859">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01296">
        <property type="entry name" value="asd_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9 12" id="KW-0220">Diaminopimelate biosynthesis</keyword>
    <keyword evidence="10 12" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="11 12" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="12" id="KW-0521">NADP</keyword>
    <keyword evidence="12 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 12" id="KW-0791">Threonine biosynthesis</keyword>
    <feature type="domain" description="Semialdhyde_dh" evidence="13">
        <location>
            <begin position="4"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="12">
        <location>
            <position position="128"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="12">
        <location>
            <position position="241"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="11"/>
            <end position="14"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="39"/>
            <end position="40"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="155"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="158"/>
            <end position="159"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="234"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="314"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="QDV54819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="338" mass="36054" checksum="68B9415FCDAB11FD" modified="2019-10-16" version="1">MIDTLAVVGATGAVGRIVLDQILQRKLPHGRLKLLASARSAGQVVTFGDQQITVELMEPSAFDGVDVVIASTPDEVSAEFAPWAVERGAIVVDESGYWRMDPKVPLIIPEVNASAIDNHQGIIASPNCSTTQMVVALAPLHNAARIKRVVVSTYQATSGAGLAGEAELMHSTRGSLDGSAPAAKTFQYPIAFNLIPQIGSEKHEGYTSEEMKMVYETRKIFGDDSIDVCPTCVRVPVAIGHSESILVETEKPLTVEQARELFANADGVTLIDDLAGRQYPMPVDSAGKDDVFVGRVRKDLSSPNGIAFWCVSDNLRKGAATNAVQIAELLAKKMASVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP16</accession>
    <name>A0A518IP16_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">2-phospho-L-lactate guanylyltransferase</fullName>
            <ecNumber evidence="1">2.7.7.68</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">cofC</name>
        <name evidence="1" type="ORF">Mal33_08000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.7.68" evidence="1"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043814">
        <property type="term" value="F:phospholactate guanylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018641">
        <property type="entry name" value="Trfase_1_rSAM/selenodom_assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36529">
        <property type="entry name" value="PTHR36529"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09837">
        <property type="entry name" value="DUF2064"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04282">
        <property type="entry name" value="glyco_like_cofC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="225" mass="25012" checksum="9D5987A52BF6173B" modified="2019-10-16" version="1">MRTLGMFTKYWQPGRVKTRLARDLGDDRAAAIYRICVEHLGGKLAHCGDKRLLIVSPDDRASDPCFARFENWSTTPQGGGDLGERMMRYFATAETDRDRLIVIGGDCPTVAPDRIEQAFDALEASRVAIGPSGDGGYYLLGIRGPWHNSLRALFDDMPWGTEEVMARTRSALNALEIEPHLLPPDRDVDTKSDLDDLLRRLPSDPASDNLRAAIERVLNTPTTES</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP55</accession>
    <name>A0A518IP55_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TonB dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_08420</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="QDV54877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039426">
        <property type="entry name" value="BtuB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30069">
        <property type="entry name" value="PTHR30069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0675">Receptor</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021778881" evidence="2">
        <location>
            <begin position="32"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="674"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="101"/>
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    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="674"/>
            <end position="688"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="818" mass="89747" checksum="9CCE4F6CFB12A77C" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPN7</accession>
    <name>A0A518IPN7_9BACT</name>
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        <submittedName>
            <fullName evidence="5">Putative ATP synthase YscN</fullName>
        </submittedName>
    </protein>
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        <name evidence="5" type="primary">yscN</name>
        <name evidence="5" type="ORF">Mal33_10050</name>
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        <name type="scientific">Rosistilla oblonga</name>
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        <lineage>
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            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
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        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="project" value="InterPro"/>
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        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
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        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
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        <property type="term" value="P:protein secretion by the type III secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="AAA+_ATPase"/>
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        <property type="entry name" value="ATPase_a/bsu_AS"/>
    </dbReference>
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        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
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        <property type="entry name" value="ATPase_T3SS_FliI/YscN"/>
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    </dbReference>
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    </dbReference>
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        <location>
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            <end position="345"/>
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    </evidence>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
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            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
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            <dbReference type="EMBL" id="QDV55037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="442" mass="47364" checksum="10BC6FC59F84D643" modified="2019-10-16" version="1">MKNAPFPELVKADDYRQTIRNAIDGRVVGSVHAIVGNRVEVRGLSVPVGSICTIHTRSGQKGAAKVIGFRDDSPILAVMDELSALSSGDPVELQSHSVNLRLGEGLIGRVVDALGRPLDGRPLPASLTSTSINMEPPASLDRPPIETVFETGIRSIDGLLTCGLGQRLGIFAGAGGGKSTLMGMLAKNSKADAVVIGLIGERGREVREFIEHTLGKKGMARSTLVVSTNDQPATMRIQAAWTATAIATALRDQGKNVVLLMDSITRFATAQREIGLAVGEPPTTRGYPPSVFSTLPKLVEQSGRTERGSITAFYAVLVDGDDNNEPISDNLRGLLDGHFFLSRKLGSEGHWPAIDVLESLSRLQTKLIPANSLAAATQLRKWLANYRTNEDLINIGAYRAGTNPELDKTIEMQPMLKQFLTQKSNEVSPLAITMKAMQTLAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPT5</accession>
    <name>A0A518IPT5_9BACT</name>
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        <submittedName>
            <fullName evidence="6">Sulfite reductase [NADPH] hemoprotein beta-component</fullName>
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        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">cysI</name>
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        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Planctomycetia</taxon>
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            <taxon>Pirellulaceae</taxon>
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    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
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                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
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                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="6 7">Mal33</strain>
        </source>
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    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
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        <property type="entry name" value="NiRdtase/SiRdtase_haem-b_fer"/>
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    <dbReference type="InterPro" id="IPR006066">
        <property type="entry name" value="NO2/SO3_Rdtase_FeS/sirohaem_BS"/>
    </dbReference>
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        <property type="entry name" value="PTHR11493"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="SSF55124"/>
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    </dbReference>
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        <property type="entry name" value="SSF56014"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="NIR_SIR"/>
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    <keyword evidence="1" id="KW-0349">Heme</keyword>
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    <keyword evidence="2 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NIR_SIR_ferr" evidence="5">
        <location>
            <begin position="92"/>
            <end position="150"/>
        </location>
    </feature>
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        <location>
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        <location>
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        <location>
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        <location>
            <begin position="214"/>
            <end position="238"/>
        </location>
    </feature>
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        <location>
            <begin position="10"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF01077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV55080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="614" mass="67890" checksum="47BC6F5613B245F2" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQ66</accession>
    <name>A0A518IQ66_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycogen synthase</fullName>
            <ecNumber evidence="2">2.4.1.11</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_11800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.4.1.11" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004373">
        <property type="term" value="F:glycogen (starch) synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
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        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13579">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="1">
        <location>
            <begin position="18"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="426" mass="47241" checksum="5FA79367457EB958" modified="2019-10-16" version="1">MHILFLTPNFPPEVNAGATRQYEHCRRWVAAGHRVTVVAPAPNWPAGKVYPGYRNKLRSVEMIDGIRVVRIATYISANQGVLLRTLSFISYMLHAAFTACFTRNVDVLVSTSPQFFAGFAGTLTRLFRRIPFVLEIRDIWPESVMAVGAMRRSKLIGFLEWLERRMYASADHIVAVGEGYRDKLIERGVQKKDISVVTNGVDLDYWQPCDADTQLRRQWGGEGKFVCAYVGTVGMAHGLDVVLDAAEIQQCEGRDDTTFWIVGDGARRQELREDAERRGLRNVQFLGQVTKPEVKQILASSDACLVHLRGTELFGTVIPSKIFETMAMNTPIVMGVRGAAQQVVLDANAGVPMVPDDPASLLQCIDRIAAFPAAFAKGRNHVMRFFDRDVLAQDMLNVLATYASPDKASIPIPTLPATSDADRKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQB0</accession>
    <name>A0A518IQB0_9BACT</name>
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        <submittedName>
            <fullName evidence="8">Sodium/glucose cotransporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">sglT_1</name>
        <name evidence="8" type="ORF">Mal33_12490</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Planctomycetia</taxon>
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            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038377">
        <property type="entry name" value="Na/Glc_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001734">
        <property type="entry name" value="Na/solute_symporter"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00474">
        <property type="entry name" value="SSF"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="sss"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50283">
        <property type="entry name" value="NA_SOLUT_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="32"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
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            <end position="95"/>
        </location>
    </feature>
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        <location>
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            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
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            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
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            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
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            <end position="247"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
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            <end position="293"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
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            <begin position="350"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
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            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="425"/>
            <end position="446"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="453"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="479"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV55279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="530" mass="57376" checksum="DBF04DC4FFD707F7" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQB1</accession>
    <name>A0A518IQB1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">Mal33_12550</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
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        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022057382" evidence="1">
        <location>
            <begin position="25"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="331" mass="36512" checksum="6774613D82566C32" modified="2019-10-16" version="1" precursor="true">MNCVWKVSALAVVMVFCLTSFVSAEQTSESNPVGLVGYEPASYDADGWLSSLKQHLRPSDHCFDDFISPMIDFVHFEDPRNLTELRPIFMTHQFPATLGPGNIPAGGSVQLFALQFRMALTERLSFIAVKDGYILDNSEGALDTLLLDSGWADVTAGLKYNFIRDTQAGTLLSGGFTYEIPLGSKQSSQAIGDGQFHFFATGGQRLLGGNAHILSSIGWQLPVDQSVQSTTVHWNNHIDMKVTDRVYLFTENSWWHWVDEAENGLALGVSGQDLLNLAATDVEGNDLVTHNVGMKFKPSGNIEAGIAYEFPLTAFKDVLEDRVTVDMIFRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQB2</accession>
    <name>A0A518IQB2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="3" type="ORF">Mal33_12470</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021834308" evidence="2">
        <location>
            <begin position="36"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="250" mass="26558" checksum="07ADE0647199C7B2" modified="2019-10-16" version="1" precursor="true">MSKASTANRLRCIATVALAASCMLAVAGLAGIAHAQPPESKGDQPPPAADLLGELDGLLDEAMQADSETNDKPEPKTDAPQAAAEPVDAMLKTLQAVDREMQQAIAGLGNGDAGPATQAAQRRALEMLQTIVDQSAQNSNQDQSQSSQRSQEQQMSQAGPEKPETDPNREGQQPQQPELGTQPGTEVGSSTDVIVNAGPLQGMREAVWGHLPERIRGELQATLPEKFLPRYRDAITEYFRQLSSGSDAKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQD8</accession>
    <name>A0A518IQD8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sulfatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_12900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008484">
        <property type="term" value="F:sulfuric ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021828598" evidence="1">
        <location>
            <begin position="25"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase" evidence="2">
        <location>
            <begin position="30"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase" evidence="2">
        <location>
            <begin position="153"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="637" mass="70693" checksum="461A91AEE5344E87" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQH5</accession>
    <name>A0A518IQH5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_13190</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="150" mass="17023" checksum="AB9B74203D2D43CD" modified="2019-10-16" version="1">MLYADDDSLPNLAEMEQPGKLSFVPFGGGHVHDWSSRLAPLRLTEFHLYDHQLPPETELRRQAARTVKQHSGCQAVLTKKRCLESYLHPDAILAANGIHVRFDDFDCVAEIVARELYRQRPGEIAWQLQSRRSQSHKGKSCETLAQHHGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQQ7</accession>
    <name>A0A518IQQ7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Site-specific tyrosine recombinase XerC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Mal33_13870</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044068">
        <property type="entry name" value="CB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025269">
        <property type="entry name" value="SAM-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13102">
        <property type="entry name" value="Phage_int_SAM_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51900">
        <property type="entry name" value="CB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core-binding (CB)" evidence="5">
        <location>
            <begin position="76"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="Tyr recombinase" evidence="4">
        <location>
            <begin position="190"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV55415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="411" mass="47267" checksum="108F60CDE0605003" modified="2019-10-16" version="1">MPRKPKYQTILCQFYEWRLIQRKENGVWYADARTTSKNRGRHSLGTRDKEEALAKLAQLDRLFAEERGVVAPSDQTDQQPLSIENGRKLFDDHTARPRGLGGTKLSTQKRYRAIFDKFEVFAADRRVRDWHNVNKSVLTAYATYLTDKGYARKTIHGEITLLKTAIKWLIAEGYIQTEPIKLPLKKAECERAYCYTSAEVAAMYKICTSTGRLQWLQNTIVGLACTGMRIEELCSLKWSDIKFDKRILTIADESGFASQTDESRSNKSSRTRHLPIRAELLDVLESLPRVDQYIFHGPRGGRLKADTVRNVLVREVITPLTKRFPKQFESERSFEDGRLHSFRHYFCSVCANTSIPERITMSWLGHADSEMVRHYYHLNDAESRRKMDQLNLLGGSDGCSATDDEQPLDGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQY1</accession>
    <name>A0A518IQY1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">prkC_5</name>
        <name evidence="5" type="ORF">Mal33_14700</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="4">
        <location>
            <begin position="46"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV55494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="392" mass="44449" checksum="3259CD2A8D05FA18" modified="2019-10-16" version="1">MLTTTRHDPNVTLTLRGKNSRTVDQELVSRYEEVLSNKKLNWTTYHRLGKLLGMGGQGKVYLSARRGTDGFTLPVAMKVFSPERYSDVRDYEAAMSRIAGIAARVAMIQNDNVLDVQNFVERNRIRIMVMEWVDGYDLQALMRPEKLKLLEGNISKRRWKYINEVILTRGPVQNRFKAGVAVAILRECLEALAALHRESIVHGDIKPSNIMLKKSGHSKLIDIGSAYDYRTPPVDRSCTPVYAAPEVLEHDNATPKSDLASLGYVLIEMLSGRPPFRGDISLRELLQAKRELPQRLNEVLPAEVTCNALLMHFCRGLIAPDPNRRFPSAEAAEHVEQGAAAFHRQLVLSDMSTEYDNDIRLWLEELNRIELSLEKEREENEDPSGNENESIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQZ0</accession>
    <name>A0A518IQZ0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Alpha-pyrone synthesis polyketide synthase-like Pks18</fullName>
            <ecNumber evidence="5">2.3.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_14810</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012328">
        <property type="entry name" value="Chalcone/stilbene_synt_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001099">
        <property type="entry name" value="Chalcone/stilbene_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011141">
        <property type="entry name" value="Polyketide_synthase_type-III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11877">
        <property type="entry name" value="PTHR11877"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02797">
        <property type="entry name" value="Chal_sti_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00195">
        <property type="entry name" value="Chal_sti_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000451">
        <property type="entry name" value="PKS_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Chal_sti_synt_N" evidence="3">
        <location>
            <begin position="4"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="Chal_sti_synt_C" evidence="4">
        <location>
            <begin position="238"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000451-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV55505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="369" mass="39747" checksum="3C6FBBC0782F074A" modified="2019-10-16" version="1">MTCSIIGLGTAQAPEIVSQEDALALSSEVICETEKQKRLLRTLFHKSGVSSRRTVIPYELGYLWHKSDSESNESGTGGNGPTTAQRMSLYRKHATPLALASATSAIHDAAVLPGDITHLVTVSCTGFAAPGVDIDLIQLLGMPSTTQRVHVGYMGCHGAINGMRTVQGLAAADPNACVLMCCVELCSLHFRMRWDLDGVVGNALFADGSGSIIAAGANWETKHPHSDSICQIEATGACLIEDTNDEMSWHIGDHGFQMRLTSGVPDCIKTYLRAWICQWLNSQGLKIEDIQRWIVHPGGPRILDAVEEALNLPPKQTQVSREVLNDLGNMSSATVLFVMERNQSQPIEGPAVVLAFGPGVMAEAALLRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IR62</accession>
    <name>A0A518IR62_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glutamate-1-semialdehyde 2,1-aminomutase</fullName>
            <shortName evidence="7">GSA</shortName>
            <ecNumber evidence="7">5.4.3.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Glutamate-1-semialdehyde aminotransferase</fullName>
            <shortName evidence="7">GSA-AT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">hemL</name>
        <name evidence="9" type="ORF">Mal33_15490</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>(S)-4-amino-5-oxopentanoate = 5-aminolevulinate</text>
            <dbReference type="Rhea" id="RHEA:14265"/>
            <dbReference type="ChEBI" id="CHEBI:57501"/>
            <dbReference type="ChEBI" id="CHEBI:356416"/>
            <dbReference type="EC" id="5.4.3.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; 5-aminolevulinate from L-glutamyl-tRNA(Glu): step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.4.3.8" evidence="7"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00317"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042286">
        <property type="term" value="F:glutamate-1-semialdehyde 2,1-aminomutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00375">
        <property type="entry name" value="HemL_aminotrans_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004639">
        <property type="entry name" value="4pyrrol_synth_GluAld_NH2Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00713">
        <property type="entry name" value="hemL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7 9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6 7" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="4 7 8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="7">
        <location>
            <position position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV55572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="441" mass="46193" checksum="987B6D955E60791E" modified="2019-10-16" version="1">MPESQAKAITAVGPNSVAAFDRACQLMPGGVNSPARAFGAVGGTPLFIESAKGPYLYDVDGRRYLDYIGSWGPMILGHQNPEVVAAIQAAILRGTSYGAPTEAESELAERIIEAVPSIDKVRLVNSGTEATMSAIRVARGYTGREKIVKFAGNYHGHVDSLLVSAGSAAATLGVPDSPGVTKGAGGDTIVLPHNDLAAVEAAFAAHPGQIAAVILEPVVGNMGCVPPCDGYLQGLRDITARDGSVLIFDEVMTGFRVAFGGAQQRYGVTPDMTTLGKIVGGGMPLGAYGGRREIMDQVLPAGKVFQAGTLSGNPVAVAAGNATLKRLKAQPPYEYLEKIGTQLANGLGQAAEAAGLPHQVQQVGSMLTLFFNGSPVTNWEQSDRNDRQQYAAFFWGLIRRGVYPPCSQFEAMFLSETHTEAMIDETIAAAKEVLQEIAASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IR85</accession>
    <name>A0A518IR85_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">50S ribosomal protein L9</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 10" type="primary">rplI</name>
        <name evidence="10" type="ORF">Mal33_15820</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Binds to the 23S rRNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the bacterial ribosomal protein bL9 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.430.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.5.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00503">
        <property type="entry name" value="Ribosomal_L9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000244">
        <property type="entry name" value="Ribosomal_L9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009027">
        <property type="entry name" value="Ribosomal_L9/RNase_H1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020594">
        <property type="entry name" value="Ribosomal_L9_bac/chp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020069">
        <property type="entry name" value="Ribosomal_L9_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036791">
        <property type="entry name" value="Ribosomal_L9_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020070">
        <property type="entry name" value="Ribosomal_L9_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036935">
        <property type="entry name" value="Ribosomal_L9_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21368">
        <property type="entry name" value="PTHR21368"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03948">
        <property type="entry name" value="Ribosomal_L9_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01281">
        <property type="entry name" value="Ribosomal_L9_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55653">
        <property type="entry name" value="SSF55653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55658">
        <property type="entry name" value="SSF55658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00158">
        <property type="entry name" value="L9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00651">
        <property type="entry name" value="RIBOSOMAL_L9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 7 10" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 7" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="RIBOSOMAL_L9" evidence="9">
        <location>
            <begin position="36"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="63"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS00651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV55605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="175" mass="19868" checksum="42B23AC112D7632C" modified="2019-10-16" version="1">MPRTTEKKLHRAHKRLPKGENGGIRLLLIHNVEHLGRQGDIVEVRRGYAMNYLMPQGLATIATDHHKRMVEKHREKLHQLELEKLSELRQYADQIATQSITIEANANDEGHLYGSVGQHEIVEALKEVGFTLADDQIRLQGPLKELGLYTVKVHLHSEVEVDLKVWVVPTVTAGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRF0</accession>
    <name>A0A518IRF0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_16550</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="SSF46565"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="186"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="150"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="233" mass="26461" checksum="07E7368C815DF692" modified="2019-10-16" version="1">MRAFDLRLNLMKTMPDASEPIDPYHKWLGIPKPQQPPTHYRLLGIEPFENNPEVIDAAASRQVAYLHQLTSGPHRRLTQKLMNEIAQARRVLMDDASREKYDAQLRDRPAEKPASPKPENKIDFGTFPAIDFGEKKTRKPIDTDSFAVVTDQSSEEPAASIGDSGAPRPRGGRAPKAWWQKNDWRIHLGISAISVAIFVVYLLFWGPGSNKRFVPEGNFEQPKIQNFDDQFID</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRM7</accession>
    <name>A0A518IRM7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_17280</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021934683" evidence="1">
        <location>
            <begin position="23"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="344" mass="37257" checksum="8CF80B3CAAF1CE74" modified="2019-10-16" version="1" precursor="true">MLVPVRIAIMFGVALTATWAVAQETDASKTYTARDSLSALDDPSLDAADCLKGFAWQPSSFEVTVETSDDDATPRTVRFASPLDTGNPINDVVTMKWYVAKDPDGATLHRPAVLVAHESGSGMTVGRLVAKTLSLYGVHAFLIHLPHYGDRRDRSIRPENQEIVKVMRQAVVDVRRGRDAIAVLPDVDADHIGLQGTSLGGFVAALAGSLDSGFDKVYITLAGGDFHGLLVNGEKDAAKMRQRLADAGYTGEKLRELVQQVEPLRIAHRLVPDRTWMFTGSEDRVVPFANAQALAKAAKLSDEHHVIVPANHYTAILYFPTIIDVIVRQSLPADAIPAALKSDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IS13</accession>
    <name>A0A518IS13_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Plasmid stabilization system protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_18660</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2310.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007712">
        <property type="entry name" value="RelE/ParE_toxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035093">
        <property type="entry name" value="RelE/ParE_toxin_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05016">
        <property type="entry name" value="ParE_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143011">
        <property type="entry name" value="SSF143011"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1277">Toxin-antitoxin system</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="103" mass="12060" checksum="F2800DA4A21BEEF8" modified="2019-10-16" version="1">MPNNKIFWTRQSREDLRSVRDHIARDAPATALTYVRKLRNSVGRLKQFPFSGEVVPEIGREDLREVLQGNYRIIYRVSERRVDILAVFHSSQIFDERDLGSAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISA5</accession>
    <name>A0A518ISA5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator BetI</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_19560</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041479">
        <property type="entry name" value="TetR_CgmR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17937">
        <property type="entry name" value="TetR_C_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="23"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="206" mass="22439" checksum="DD608E14792B5135" modified="2019-10-16" version="1">MPTDRSVGMIAAMSNCEQPSEATDTVTRILDAVMVLIRDGGLPAVTLSAVCRKAGLSKGGLMHHYPSKEALVNAFLQRGGQEHLALIQQAIERHPAGSGNRLRAYVDLLVGESTTLQCDEDRDCAAVMMALIQGGRDSDEVRKFYESLHQMLSGDGVSDEFLELILATVDGVWLQSVIEPPETIGPRSERIRQNLRRLIANEIAGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISE2</accession>
    <name>A0A518ISE2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_19960</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="212"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="239"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="939" mass="104511" checksum="03911C2E399C0092" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISG2</accession>
    <name>A0A518ISG2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">31-O-demethyl-FK506 methyltransferase FkbM</fullName>
            <ecNumber evidence="2">2.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">fkbM</name>
        <name evidence="2" type="ORF">Mal33_20030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.1.1.-" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006342">
        <property type="entry name" value="FkbM_mtfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05050">
        <property type="entry name" value="Methyltransf_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01444">
        <property type="entry name" value="fkbM_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_21" evidence="1">
        <location>
            <begin position="23"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="220" mass="24379" checksum="E6525463530B1ECC" modified="2019-10-16" version="1">MCREADEFPAFFTPRDDDALFLDCGANIGVTMLECKRRWPQAKIICFEPDPFAFAALQRNVDVNDIPGVRCIEAAVSDCEGQATFYGDMSPTADGRGNSLNAGWAERPGSTSRTVACRRLSPLIGDQQVDFLKLDIEGSEQAVLQEIADKLQQIQAIYVEVHETPATMAENSVEAITSQLTAAGFTVDAQQRHYEFALPPHLAQWQAAARPRQTQLLCWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISJ6</accession>
    <name>A0A518ISJ6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Type II/IV secretion system protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_20470</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GSP E family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001482">
        <property type="entry name" value="T2SS/T4SS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037257">
        <property type="entry name" value="T2SS_E_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007831">
        <property type="entry name" value="T2SS_GspE_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00437">
        <property type="entry name" value="T2SSE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05157">
        <property type="entry name" value="T2SSE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160246">
        <property type="entry name" value="SSF160246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00662">
        <property type="entry name" value="T2SP_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T2SP_E" evidence="2">
        <location>
            <begin position="387"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="570" mass="62855" checksum="88D825C11BDA455B" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISS2</accession>
    <name>A0A518ISS2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">GDP-L-fucose synthase</fullName>
            <ecNumber evidence="2">1.1.1.271</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4-reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">fcl_2</name>
        <name evidence="2" type="synonym">fcl</name>
        <name evidence="4" type="ORF">Mal33_21210</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>GDP-beta-L-fucose + NADP(+) = GDP-4-dehydro-alpha-D-rhamnose + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:18885"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57273"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57964"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.271"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Nucleotide-sugar biosynthesis; GDP-L-fucose biosynthesis via de novo pathway; GDP-L-fucose from GDP-alpha-D-mannose: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.271" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00128">
        <property type="reaction ID" value="UER00191"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050577">
        <property type="term" value="F:GDP-L-fucose synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070401">
        <property type="term" value="F:NADP+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042351">
        <property type="term" value="P:'de novo' GDP-L-fucose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd05239">
        <property type="entry name" value="GDP_FS_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00956">
        <property type="entry name" value="GDP_fucose_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028614">
        <property type="entry name" value="GDP_fucose/colitose_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="2 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="3">
        <location>
            <begin position="14"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="2">
        <location>
            <position position="143"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="17"/>
            <end position="23"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="112"/>
            <end position="115"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="170"/>
            <end position="173"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="186"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="209"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="216"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="276"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="2">
        <location>
            <position position="114"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="2">
        <location>
            <position position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV56142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="322" mass="35488" checksum="3A92C82C330B1D68" modified="2019-10-16" version="1">MNADTSAPSNQRLFVAGHRGMVGDAICRRVANDPSIELLTAGRDVVDLCDAEAVDQYYADNRPDAVVVAAAKVGGIYANSQYPVEFLSQNMKIAMNCVEAAYKQGVRRLLFLGSTCIYPRDAPQPLVESALLSGPLESTNEAYAIAKIAGLKLCQFYRQQYGVMFHSAMPTNLYGPGDNYHPENSHVLPALLRRFHEAKEEQRDSVTIWGSGSPRREFLHVDDLADAVMHLMSASHPPDWVNVGTGEDLTILELAKKIAAVVGFEGEIKTDPSKPDGTPRKVTDVSRLHEMGWRHEIDLDRGLKQTYASFLKEEAESGLRQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IST1</accession>
    <name>A0A518IST1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase</fullName>
            <ecNumber evidence="1">2.3.1.89</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">dapH</name>
        <name evidence="1" type="ORF">Mal33_21300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.3.1.89" evidence="1"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047200">
        <property type="term" value="F:tetrahydrodipicolinate N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="174" mass="18604" checksum="6783E7564BEFA866" modified="2019-10-16" version="1">MAIYRLGDRTPELAPDCFVAEEATLIGRVAIGSEASVWPSAVLRGDIELIDIGARSSVQDGTVMHTDPGCPLTVGEGVTIGHQATLHGCTIEDGALIGMQAIVLNRAVIGRNSLVGAGALITEGKTFPENSLILGAPARRVRELTEEEIENLAKTAKRYVVRSRDYRENLVRLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISY3</accession>
    <name>A0A518ISY3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">Triosephosphate isomerase</fullName>
            <shortName evidence="3">TIM</shortName>
            <shortName evidence="3">TPI</shortName>
            <ecNumber evidence="3 4">5.3.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Triose-phosphate isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">tpiA</name>
        <name evidence="5" type="ORF">Mal33_21820</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 4">
            <text>D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate</text>
            <dbReference type="Rhea" id="RHEA:18585"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="5.3.1.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 4">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 4">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate from glycerone phosphate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 4">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the triosephosphate isomerase family.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.1" evidence="3 4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00189"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00138"/>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004807">
        <property type="term" value="F:triose-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00311">
        <property type="entry name" value="TIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00147_B">
        <property type="entry name" value="TIM_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035990">
        <property type="entry name" value="TIM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022896">
        <property type="entry name" value="TrioseP_Isoase_bac/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000652">
        <property type="entry name" value="Triosephosphate_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020861">
        <property type="entry name" value="Triosephosphate_isomerase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21139">
        <property type="entry name" value="PTHR21139"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00121">
        <property type="entry name" value="TIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51351">
        <property type="entry name" value="SSF51351"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00419">
        <property type="entry name" value="tim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00171">
        <property type="entry name" value="TIM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51440">
        <property type="entry name" value="TIM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 3 4" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="3 4" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="2 3 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="3">
        <location>
            <begin position="9"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="3">
        <location>
            <begin position="234"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="active site" description="Electrophile" evidence="3">
        <location>
            <position position="95"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="167"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="213"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV56201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="250" mass="25440" checksum="30EC0BF9F728F21F" modified="2019-10-16" version="1">MRKPFICGNWKMNTRGECGVALAKAVAAGIPAGSEVEVGVCPPACYLGGVGAAIAGSAVGLGAQNMLAEADGAFTGEINPAMLNDLGCRYVILGHSERRQFFGETNEGVSKKTDAALAAGLVPIVCVGETLEQREGNQTEAVVAEQIAGSLAGISAEQLPTVVIAYEPVWAIGTGKVASPEQAEAVHAHIRKLLSDKFGSEAAEKVRIQYGGSVKPGNAAELLGQPNIDGALVGGASLKAEDFLGIIAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IT05</accession>
    <name>A0A518IT05_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_21740</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="56"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="185" mass="21090" checksum="19E44B5D2BE1CE54" modified="2019-10-16" version="1">MGITYFKRYRMELDLERFVPSEYRLPEGYEVLPWSEDLVRQHGLAKHEAFQWELDANVFPCLGQRDGCLRLMQEIAGRSNFVPEATWLLRFREPDSRKPQPVGTVQGIQSEGWGALQNLGIAKPHRGLGLGTILLNLATQGFQKIGLTRMHLEVTTDNTAALRLYERLGYRRAKTVFKAADVAMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IT56</accession>
    <name>A0A518IT56_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_22490</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="159" mass="18297" checksum="B5E50ADA5993D057" modified="2019-10-16" version="1">MNGNYRHTQRAPLCLLIYGAAVMFLVLGWALRNESVIQWIFPPTGLLMLVLAASFHHLTVEDKEDRLSISFGPIPLFRRTIKYENIVSIEVGQTTILDGWGIHMSFRGGWGWNIWSRDCVVLRLRKGILRVGTDDAEQLSVFLNRRLSDQEPFHEEDET</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IT91</accession>
    <name>A0A518IT91_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Recombination protein RecR</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">recR</name>
        <name evidence="9" type="ORF">Mal33_22940</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the RecR family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01025">
        <property type="entry name" value="TOPRIM_recR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00017">
        <property type="entry name" value="RecR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000093">
        <property type="entry name" value="DNA_Rcmb_RecR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023627">
        <property type="entry name" value="Rcmb_RecR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023628">
        <property type="entry name" value="Rcmb_RecR_C4-type_Zn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015967">
        <property type="entry name" value="Rcmb_RecR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034137">
        <property type="entry name" value="TOPRIM_RecR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30446">
        <property type="entry name" value="PTHR30446"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02132">
        <property type="entry name" value="RecR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13662">
        <property type="entry name" value="Toprim_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00493">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111304">
        <property type="entry name" value="SSF111304"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00615">
        <property type="entry name" value="recR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01300">
        <property type="entry name" value="RECR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5 7" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="6 7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="1 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Toprim" evidence="8">
        <location>
            <begin position="81"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C4-type" evidence="7">
        <location>
            <begin position="58"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV56312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="199" mass="22061" checksum="E08C660B2192A3C6" modified="2019-10-16" version="1">MAELTHSVADMIDQLGRLPGIGRKSAERLAYHLLRVPKTEALALADSIRSVRENVRYCEQCFNLSEAARCPICTDPNRDTTRLCIVEQPRDLISLEQSGMYRGLFHVLLGRIAPLDGIGPDQLTIDPLVDRVRLGKFTEVIMATNPTVEGDGTSLYISNLLQEYPVEITRLARGITAGSVLEFTNKEILADALNGRQKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITC5</accession>
    <name>A0A518ITC5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_23050</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013517">
        <property type="entry name" value="FG-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028994">
        <property type="entry name" value="Integrin_alpha_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13517">
        <property type="entry name" value="FG-GAP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69318">
        <property type="entry name" value="SSF69318"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1235" mass="135387" checksum="12FBF242189969F6" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITE0</accession>
    <name>A0A518ITE0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Branched-chain-amino-acid aminotransferase</fullName>
            <shortName evidence="15">BCAT</shortName>
            <ecNumber evidence="15">2.6.1.42</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">ilvE_1</name>
        <name evidence="15" type="synonym">ilvE</name>
        <name evidence="16" type="ORF">Mal33_23330</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 15">Acts on leucine, isoleucine and valine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 15">
            <text>2-oxoglutarate + L-isoleucine = (S)-3-methyl-2-oxopentanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24801"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:35146"/>
            <dbReference type="ChEBI" id="CHEBI:58045"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 15">
            <text>2-oxoglutarate + L-leucine = 4-methyl-2-oxopentanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:18321"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:17865"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57427"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 15">
            <text>2-oxoglutarate + L-valine = 3-methyl-2-oxobutanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24813"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57762"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4 14">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="6 15">Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 4/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="8 15">Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 4/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7 15">Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 4/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9 13">Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.42" evidence="15"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00047">
        <property type="reaction ID" value="UER00058"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00048">
        <property type="reaction ID" value="UER00073"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00049">
        <property type="reaction ID" value="UER00062"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052656">
        <property type="term" value="F:L-isoleucine transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052654">
        <property type="term" value="F:L-leucine transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050048">
        <property type="term" value="F:L-leucine:2-oxoglutarate aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052655">
        <property type="term" value="F:L-valine transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001544">
        <property type="entry name" value="Aminotrans_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018300">
        <property type="entry name" value="Aminotrans_IV_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036038">
        <property type="entry name" value="Aminotransferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005785">
        <property type="entry name" value="B_amino_transI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043132">
        <property type="entry name" value="BCAT-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043131">
        <property type="entry name" value="BCAT-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01063">
        <property type="entry name" value="Aminotran_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56752">
        <property type="entry name" value="SSF56752"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01122">
        <property type="entry name" value="ilvE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00770">
        <property type="entry name" value="AA_TRANSFER_CLASS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 15" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="15 16" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="12 15" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="11 14" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="15 16" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00003109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00004824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00004931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00005072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00009320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU004106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU004516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU364094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="QDV56351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="285" mass="31102" checksum="5D8F5CB089EFD0FE" modified="2019-10-16" version="1">MSLQISLNGQLVPKEDAKISVFDHGLLYGDGVFEGMRSYAGKIFKLDDHLDRLWDSARAICLELPITREQLAEDCKATLAANNIIDGYIRLIVTRGAGSLGLDPNRCTNPQVIIIADKISLYPSEYYENGLHLVTASTIRNHPAALSPRVKSLNYLNNIIAKMEGLQAGCVEALMLNHKGDVAECTGDNVFIVDRGVLKTPSTDSGILEGITRNAVLEIAADLGIPTREMTLTRHDLFVADECFLTGSAAEVVPVVQLDNRPIGDGKPGPITKRLLEAFHKLVRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITL4</accession>
    <name>A0A518ITL4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Thiol-disulfide oxidoreductase ResA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">resA_3</name>
        <name evidence="2" type="ORF">Mal33_24170</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016209">
        <property type="term" value="F:antioxidant activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004155">
        <property type="entry name" value="PBS_lyase_HEAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00567">
        <property type="entry name" value="EZ_HEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="1">
        <location>
            <begin position="239"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="421" mass="47534" checksum="BEFA5214023FAF95" modified="2019-10-16" version="1">MQRTLGSAVSIDRRRHTTVGGLGNGVKPVLITREQRKDPAMGSHSTWSYVVFIVLVFSIATDVSGQTAAIFDRVNAHEFHPLNEDGSFTKDRVLAKHGVSDLANDDWKVRLLAIRDLTRSLPQQLDAVVEGLEHNDPHVRQIAAAALGIARQKEAASALQHVLEADPMALVRSQAAMSLGQLESVESLEFLRQFFERDKSRDVRHQCELAIDQIEKRLGATDAQLAAFRALDEASFEQVQVGQPAPDFTLNDSEGNPWQLSRAGNGKWTVLIWIFADWCPVCHGEFKELMSMKKEFDEANAVVATIQCHDLYRCRLMVGKEKDAAYWFSKTSFQQKYLRSVWWPHLSDLAGRVGAQYGVDPMSFAVHAEYVNRPSTIIIDPEGRVRLTYYGTFWGDRPSLHETLEMIKSEEFGFEHPRRLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITM1</accession>
    <name>A0A518ITM1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_24290</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="56" mass="5793" checksum="33D6450B3D075166" modified="2019-10-16" version="1">MGLGGSEKYQAGVKQQPAGGAVSGNIILPSPLRSVTASFCDRDLFNLNYQSPHASG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITS1</accession>
    <name>A0A518ITS1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_24780</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="217" mass="24759" checksum="E0C25FB7B0D9F62A" modified="2019-10-16" version="1">MASAIANSIPDLIRIAESQFRMRATSFDHFRPHFLHDDVTVHAFRRSGNDDHLDDHTYDGLRDWFENQGWIVSRQRFRKPPFDGVEHIYIAPIETLHPSVAFHATRTVSIKSIENNGLCPGLRERCNTERLDSIGNIYAASKLGSPGDESRNNFGTAHWWREHLAHENRFDDPVWSILQIDVAAVGGLTCFRDIWSRTGIVIRANVPIDGRFVKTVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITW4</accession>
    <name>A0A518ITW4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Biotin--[biotin carboxyl-carrier protein] ligase</fullName>
            <ecNumber evidence="2">6.3.4.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">birA</name>
        <name evidence="4" type="ORF">Mal33_25210</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="6.3.4.15" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004077">
        <property type="term" value="F:biotin-[acetyl-CoA-carboxylase] ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd16442">
        <property type="entry name" value="BPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004408">
        <property type="entry name" value="Biotin_CoA_COase_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003142">
        <property type="entry name" value="BPL_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004143">
        <property type="entry name" value="BPL_LPL_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008988">
        <property type="entry name" value="Transcriptional_repressor_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02237">
        <property type="entry name" value="BPL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03099">
        <property type="entry name" value="BPL_LplA_LipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50037">
        <property type="entry name" value="SSF50037"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00121">
        <property type="entry name" value="birA_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51733">
        <property type="entry name" value="BPL_LPL_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0092">Biotin</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BPL/LPL catalytic" evidence="3">
        <location>
            <begin position="6"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00024227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV56529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="274" mass="29731" checksum="A704C21221F3FAF1" modified="2019-10-16" version="1">MQVDWQGPDAVLQLLSRSGWLRSIRWVPEVDSTNRLAKSLADQADRPTPMLIVAKSQTQGRGRLGRSWFSDSGTLTFSLMLAAPQLAADRTRWPQLALVAGLAVCDVVGEVVEPVAVQLKWPNDVYLAGGKVAGVLIETAGHDNDHVVIGIGLNVATDLSKAPAEVQQRARSIRDYADHPVETFAVLPEIIDRIAVRIADWRTDSAAIANDFSKVCLLRGRRVAIDTAGQTLEGACLGIDGDGALRVRRDDGEVVEVRSGEVVRWSDEVEVHDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITW8</accession>
    <name>A0A518ITW8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_25240</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028978">
        <property type="entry name" value="Chorismate_lyase_/UTRA_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64288">
        <property type="entry name" value="SSF64288"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="183" mass="20852" checksum="56EE04B2F0EE7CCA" modified="2019-10-16" version="1">MTSEIANLPPSVDLHALIALFYDRSEELGEFTQQPAEALPPAYQQLLAHHAHMTVTVERFHNSLVDVHVHRTDTDENRYAREITLARQSDGEVVQYGIVRLNHEYLEPQVWKEIASEEIPLGRVLIQHNVLREVVLEKLWQVKCAPPLARFLNVSPGDIVYGRTAMIFCNKEPAIELLEIVVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITY9</accession>
    <name>A0A518ITY9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphotransferase enzyme family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_25480</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="APH" evidence="1">
        <location>
            <begin position="33"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="330" mass="36570" checksum="427751574794897E" modified="2019-10-16" version="1">MNEIPESILHQLLAPRGATRIEPAASGWGLSGARVYRVEADGTSYCLRRWPLGTELARVDQVHRFMTAARSGGCLLVPEVGCRQAAPTRIASDNCVWDLTRWMPGRCLSRDELSLPRIEQAAAAIASIHQSVAAVDCQDQVAPAVLARIARIEQLTHNNPFDRALASPPPLQSLARRAIALWNANHASIRYRLQEVAAVRVRTQWVLRDVHLEHLLFDNLGDAAETVSAIVDYDAVRIDTPATDLARFLGSFGGIPPQWYNTAIASYRRICPLAADSERLIPLLDAATHLIASANWTQWLCVENRRFDAGAEKAVDRFREAVDRAEMLFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUE1</accession>
    <name>A0A518IUE1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_27120</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="110" mass="11847" checksum="C5D539E2FC2C5D28" modified="2019-10-16" version="1">MTVNQIEGGVIIFHFRDGPLEGEIVRSDVATDRDSTNAATTFWAMTQGGKIGRTLKTTGGGTIGDLLAGGVPLDGKQLGTAKHLYRVIDRTESPKQIEIFVEFVKSLAKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUH3</accession>
    <name>A0A518IUH3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_27440</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021767052" evidence="2">
        <location>
            <begin position="25"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="155"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="238"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="287" mass="29108" checksum="98037B8912526B25" modified="2019-10-16" version="1" precursor="true">MARSLFLMILVVAGSFGFQSPSQAQSPVLAELYGRGVHAYYCGDLIDAHRYLSMAIDNGSRDPRAHYFRGVVNAATGRQLEAEADWQLGAQLEIQGEYGAGIGRALQRVQGPVRMEMENIRQLARLEYRANQSAKNQARYNDLKAAEGEVLRGNKPAAPAAPAAPAPAAPAAPAAGGDTNNPFDDKAAAPGEPVPDAKNNPFNDDPAEPAAPAAGADPFGGGAEPAAPAADADPFGAPAPAAPAPAAPAPAPAADPFGGGDPFGGDAAPAGDGDMSDPFGGSDPFGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUR0</accession>
    <name>A0A518IUR0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_28250</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10600">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021866">
        <property type="entry name" value="SpoIIAA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038396">
        <property type="entry name" value="SpoIIAA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11964">
        <property type="entry name" value="SpoIIAA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="118" mass="13811" checksum="DA0157EEC4ACE30E" modified="2019-10-16" version="1">MAIVLHEDFDTGLLEVKVSDKLSKEDYEHFEPAVERLIESCGKIKILLEMHDFHGWEMGAVWEDIKFATKHCRDIEKIAMVGETKWEKWMSAICKPFTMSTIKYFDAGQDQEARQWLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUY3</accession>
    <name>A0A518IUY3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Sulfatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_28810</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="PTM">
        <text evidence="1">The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008484">
        <property type="term" value="F:sulfuric ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022109128" evidence="2">
        <location>
            <begin position="22"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase" evidence="3">
        <location>
            <begin position="25"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="modified residue" description="3-oxoalanine (Cys)" evidence="1">
        <location>
            <position position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR600917-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV56880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="530" mass="59032" checksum="C1A8D8F29C77E42C" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IV10</accession>
    <name>A0A518IV10_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_29270</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="69" mass="7562" checksum="FD49BA1BCFE2EC6F" modified="2019-10-16" version="1">MRYEEFRFAKLTSTLLVLLAMVAGTTSVGCGPTSSPEDSAGEAEVFDEDAYAEEMAAEQKRVAKELREQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IV30</accession>
    <name>A0A518IV30_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CheX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_29530</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028976">
        <property type="entry name" value="CheC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038756">
        <property type="entry name" value="CheX-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028051">
        <property type="entry name" value="CheX-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39452">
        <property type="entry name" value="PTHR39452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13690">
        <property type="entry name" value="CheX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103039">
        <property type="entry name" value="SSF103039"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0145">Chemotaxis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CheX" evidence="2">
        <location>
            <begin position="44"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="166" mass="17418" checksum="7BEA180CCAD11024" modified="2019-10-16" version="1">MLTTENEAFQKAVEEIFNSCLGCEVKLKEIGDSTAADRINEIKGIIGISGAICGTAALSVSRDFAYKATGALLGETPAELNSDVVDAVGEIVNMIAGRARVLLGNEATNMSLPSVIMGQCEIAFGSENHGTCLRFETAWGPVSMELVLKQQSKSAIPNVTPVAILA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVN0</accession>
    <name>A0A518IVN0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GTP cyclohydrolase 1 type 2</fullName>
            <ecNumber evidence="3">3.5.4.16</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_31490</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GTP cyclohydrolase I type 2/NIF3 family.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.16" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003934">
        <property type="term" value="F:GTP cyclohydrolase I activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002678">
        <property type="entry name" value="DUF34/NIF3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036069">
        <property type="entry name" value="DUF34/NIF3_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13799">
        <property type="entry name" value="PTHR13799"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01784">
        <property type="entry name" value="NIF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102705">
        <property type="entry name" value="SSF102705"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00486">
        <property type="entry name" value="YbgI_SA1388"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="125"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="267" mass="28923" checksum="1C3DF66EFD2EE314" modified="2019-10-16" version="1">MPLQIEHVCQSLAAVAPLRLAESWDNVGLLIGDRRRECRRVMTCLTITPDVVAEATDQQVDLIVAHHPLPFKPIARLTTDSTASGMVLELAAHRIAVYSAHTAFDSARRGINQQLAEGLQLTDIAPLQPDPADTSETPDGSGRYGRVAATTLEPILRRAADFLKLPNVRYVGDPDAAVTKVALACGSGGSFLDAARRKGCDCMLTGESNFHGCLEAQSQGIGLILVGHYASERFAMEQLADHLSQEHDELTVWASRSESDPLRQFSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IW02</accession>
    <name>A0A518IW02_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_32610</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011453">
        <property type="entry name" value="DUF1559"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07596">
        <property type="entry name" value="SBP_bac_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="307" mass="33534" checksum="CEC630AEC045D8F0" modified="2019-10-16" version="1">MKTYAPTRRAFTLVELLVVIAIIGILVGLLLPAVQAAREAARRMSCSNNMKQLGLAMHNYHDTFRKFPYGYVDSGMVTRKRDCWMQRLLPFFEEGNMQDLYEQQNPEWIMDVDVTIKDRQIAALLCPSDTATPGLGANGGVRSGGAGFQGNYVMCTGDQYMYHTARGRGLIYAYSDTKFSSVTDGTSTSLMGGESIRGGGDTGGWGGAGGYWGGGRWGGYGFTAMEAPNTPVPDQHYTCKSTTYRDLPCISLVGADETRNSLRSRHPGGVQCFRIDGSTQFLSETIQLDVYRAMATIDNGEVVSDNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IW73</accession>
    <name>A0A518IW73_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Pyridoxal phosphate homeostasis protein</fullName>
            <shortName evidence="1">PLP homeostasis protein</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_33520</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02087">
        <property type="entry name" value="PLP_homeostasis"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001608">
        <property type="entry name" value="Ala_racemase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011078">
        <property type="entry name" value="PyrdxlP_homeostasis"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10146">
        <property type="entry name" value="PTHR10146"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01168">
        <property type="entry name" value="Ala_racemase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004848">
        <property type="entry name" value="YBL036c_PLPDEIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="SSF51419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00044">
        <property type="entry name" value="TIGR00044"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ala_racemase_N" evidence="4">
        <location>
            <begin position="48"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="1 2">
        <location>
            <position position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR004848-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV57348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="237" mass="25939" checksum="1BA3AC6CFAB65CB5" modified="2019-10-16" version="1">MTDQVSDSVQAKIDANWRSVSEQVADACRAVGRGPDEVTIVGVTKYVDVPLTQALLRAGCRDLGENRPQVLWQKAEAMSDPTIRWHLIGHLQRNKSRRTIPLVHRLHSIDTLRLAETVAQQSGEAGQTTSCLLEVNVSGDEQKHGFRPAEIEKIVPDLIALPNLKILGLMGMASFDQPNHDPAIDFAALRELRDRLTVTTGLPLPELSMGMSGDFQAAIAEGSTCVRIGTRLFEGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWA7</accession>
    <name>A0A518IWA7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FecR protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_33750</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006860">
        <property type="entry name" value="FecR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012373">
        <property type="entry name" value="Ferrdict_sens_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30273">
        <property type="entry name" value="PTHR30273"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04773">
        <property type="entry name" value="FecR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="FecR" evidence="2">
        <location>
            <begin position="225"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="574" mass="61581" checksum="97B670DEB7D6830F" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWV9</accession>
    <name>A0A518IWV9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Y1_Tnp domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_35900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002686">
        <property type="entry name" value="Transposase_17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036515">
        <property type="entry name" value="Transposase_17_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM01321">
        <property type="entry name" value="Y1_Tnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143422">
        <property type="entry name" value="SSF143422"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Y1_Tnp" evidence="1">
        <location>
            <begin position="13"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="357" mass="40744" checksum="4D261703A41C4E76" modified="2019-10-16" version="1">MTMARKYLVDPAVTRWYHCISRCVRQTLLLHDNSRDTKRDWRQWIEDRLQLLDSNFAISVGGFSVMDNHLHVLCRLDPEAADRWSPQEVMRRWIAIYPPKTLKSDDEKAVRQWLEKHAKDARRVTLLRDRLKNLGWFMKSLKEPLARLANKADGCRGTFWEARYKSIAILDDDALLATSTYIDLNPLAAGVVSTPEQGLHTSIHQRVEHVCQKGEKEIERLKAARRGSVAASVAAGAMEQDHWLVPIEDRRTALRDEAGGLECREGMLESFPLGSYLLVLDYTGRLFREGKANMEAGVKEVFDRLSSTLEAWQTRADKMLHAKSLRGSFFASNNQTVAEITTAPGHHFRNLSPQPPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWX4</accession>
    <name>A0A518IWX4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Multidrug resistance protein MdtN</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_35990</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039562">
        <property type="entry name" value="MFP_biotin_lipoyl_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13533">
        <property type="entry name" value="Biotin_lipoyl_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GAF" evidence="1">
        <location>
            <begin position="245"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="domain" description="Biotin_lipoyl_2" evidence="2">
        <location>
            <begin position="402"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="627" mass="68712" checksum="3575F68EE420D95A" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXA0</accession>
    <name>A0A518IXA0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Oligopeptide transport ATP-binding protein OppD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">oppD</name>
        <name evidence="6" type="ORF">Mal33_37270</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015833">
        <property type="term" value="P:peptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013563">
        <property type="entry name" value="Oligopep_ABC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08352">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01727">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="6"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="42"/>
            <end position="49"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV57714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="326" mass="35813" checksum="5638897DD7B04C86" modified="2019-10-16" version="1">MNKPLLSVENLGVGFGTDDGMLDAVRGVSFDVAAGETVGIVGESGSGKSVTNLAMMGLIPMPPGKITSGRAMFDNQDLLAMSQEQLSAVRGRRIAMIFQDPMTALNPFLTVEDQLTEVTRLHLGLNRRQATEHAIEMLTQVGISAPEKRLHDYPHQFSGGMRQRVMIAMALSCNPEILIADEPTTALDVTIQAQILDLLKKLQREHNTAIVMITHDLGVVANICHRVLVMYAGRIVERAPVDQLFANPQHPYTQGLLHSIPRWDQHGSELLKAIEGQPPHLAELPSGCAFHPRCPHKIDRCLSEDPRLENTSAERQKACFVDLNLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXA5</accession>
    <name>A0A518IXA5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATPase family associated with various cellular activities (AAA)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_37340</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011703">
        <property type="entry name" value="ATPase_AAA-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041628">
        <property type="entry name" value="ChlI/MoxR_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07726">
        <property type="entry name" value="AAA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17863">
        <property type="entry name" value="AAA_lid_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="1">
        <location>
            <begin position="46"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="333" mass="37143" checksum="893FFAFDBC81B5B2" modified="2019-10-16" version="1">MSTLADSMQQQAEEFQQRYAAVREQIGRVIVGHDDIVHGVLTSMLIGGHCLLEGVPGLGKTMLVRTLAETLDLQFSRIQFTPDLMPADILGTNMIVERDGQKNFEFQRGPIFTQILLADEINRATPKTQSALLETMQEGTVTAGGTRYTMDKPYFVLATQNPIEQEGTYPLPEAQLDRFMFKLVVGYSSREQLATIIARTTSGETVQPTKVMDGAEIVRWQHLVREVILASHVQDYIVRLVLATHPDGPLATPITNQYVRWGSSPRGAQTLALAAKVRALLGGRFNVSFEDVRRVYLPAMRHRVLLNFEAQAEGIEPDRVLLEILEKVAEKAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXI3</accession>
    <name>A0A518IXI3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Planctomycete cytochrome C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Mal33_38030</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011429">
        <property type="entry name" value="Cyt_c_Planctomycete-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011444">
        <property type="entry name" value="DUF1549"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022655">
        <property type="entry name" value="DUF1553"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006558">
        <property type="entry name" value="LamG-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07635">
        <property type="entry name" value="PSCyt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07583">
        <property type="entry name" value="PSCyt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07587">
        <property type="entry name" value="PSD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00560">
        <property type="entry name" value="LamGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021834310" evidence="6">
        <location>
            <begin position="17"/>
            <end position="1045"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="7">
        <location>
            <begin position="33"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="413"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV57788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1045" mass="116826" checksum="A24F575E11E79655" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXV9</accession>
    <name>A0A518IXV9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Putative 3-methyladenine DNA glycosylase</fullName>
            <ecNumber evidence="5">3.2.2.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Mal33_39380</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the DNA glycosylase MPG family.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.-" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003905">
        <property type="term" value="F:alkylbase DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00540">
        <property type="entry name" value="AAG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00527">
        <property type="entry name" value="3MGH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011034">
        <property type="entry name" value="Formyl_transferase-like_C_sf"/>
    </dbReference>
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        <property type="entry name" value="MPG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036995">
        <property type="entry name" value="MPG_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10429">
        <property type="entry name" value="PTHR10429"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02245">
        <property type="entry name" value="Pur_DNA_glyco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50486">
        <property type="entry name" value="SSF50486"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00567">
        <property type="entry name" value="3mg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4 5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV57922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="213" mass="23676" checksum="308532ADE83992DB" modified="2019-10-16" version="1">MGFEKQTTKWPRPLAESFYRRPTAIVARSLIGKTLLHRNDDRIVGGVIVETEAYLADGDPACHAARGMTPRNATMFGPPGRLYVYTIHAKYCLNAVTQRAGVGSAVLIRAIQPRWGVPQMQQRRGQQATDRLCRGPSMLCQALAIDLQHDGVCLTEDSSIWIGRAVERIATERIIAVPRIGISQAKDLPLRFLLQDSPFVSGPKYWHRTGARS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IY10</accession>
    <name>A0A518IY10_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Enterochelin esterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">fes</name>
        <name evidence="6" type="ORF">Mal33_39900</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Fes family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008849">
        <property type="term" value="F:enterochelin esterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006826">
        <property type="term" value="P:iron ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021764">
        <property type="entry name" value="Enterochelin_esterase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000801">
        <property type="entry name" value="Esterase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11806">
        <property type="entry name" value="DUF3327"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00756">
        <property type="entry name" value="Esterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="SSF81296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022086691" evidence="4">
        <location>
            <begin position="26"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3327" evidence="5">
        <location>
            <begin position="194"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF11806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV57974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="545" mass="59618" checksum="BCEAC5B0F8039A99" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IY52</accession>
    <name>A0A518IY52_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ribosomal N-acetyltransferase YdaF</fullName>
            <ecNumber evidence="2">2.3.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ydaF</name>
        <name evidence="2" type="ORF">Mal33_40330</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.3.1.-" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="18"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="200" mass="22677" checksum="AA716A29A3CD4B72" modified="2019-10-16" version="1">MNDPLPWPQPVTLHGPLATLEPLSREHHDPLAAAVSDGQLWKLWYTNVPTPDAMMAEIERRLNLQASGSMLPFVVRDANDTIVGMTTYMHIDAENRRLEIGSTWYAQRVQRTGLNTQCKLLLMSHAFETLRCIAVEYRTSSLNLASRRAIERLGAKLDGVLRSHQRHRDGTLRDTCVYSILQHEWPAVKSHLEFKLQAGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IY69</accession>
    <name>A0A518IY69_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_40550</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="43" mass="4681" checksum="6CD0E56AE24AD634" modified="2019-10-16" version="1">MGYFLEGLLEKRRRFAYAINSLAAPPNGARPHGGSAVLGRRPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IY96</accession>
    <name>A0A518IY96_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Protein translocase subunit SecA</fullName>
            <ecNumber evidence="10">7.4.2.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">secA</name>
        <name evidence="14" type="ORF">Mal33_40610</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell membrane</location>
            <topology evidence="10">Peripheral membrane protein</topology>
            <orientation evidence="10">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="10">Distribution is 50-50.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the SecA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="7.4.2.8" evidence="10"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0065002">
        <property type="term" value="P:intracellular protein transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017038">
        <property type="term" value="P:protein import"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd18803">
        <property type="entry name" value="SF2_C_secA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01382">
        <property type="entry name" value="SecA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000185">
        <property type="entry name" value="SecA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011115">
        <property type="entry name" value="SecA_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014018">
        <property type="entry name" value="SecA_motor_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011130">
        <property type="entry name" value="SecA_preprotein_X-link_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044722">
        <property type="entry name" value="SecA_SF2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036670">
        <property type="entry name" value="SecA_X-link_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30612">
        <property type="entry name" value="PTHR30612"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07517">
        <property type="entry name" value="SecA_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01043">
        <property type="entry name" value="SecA_PP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00906">
        <property type="entry name" value="SECA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00957">
        <property type="entry name" value="SecA_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00958">
        <property type="entry name" value="SecA_PP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81767">
        <property type="entry name" value="SSF81767"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51196">
        <property type="entry name" value="SECA_MOTOR_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-1278">Translocase</keyword>
    <keyword evidence="8 10" id="KW-0811">Translocation</keyword>
    <keyword evidence="1 10" id="KW-0813">Transport</keyword>
    <feature type="domain" description="SECA_MOTOR_DEAD" evidence="13">
        <location>
            <begin position="1"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="11">
        <location>
            <begin position="78"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="12">
        <location>
            <begin position="422"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="76"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="497"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="QDV58044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="616" mass="68904" checksum="47FCBBBF27B36D63" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYB5</accession>
    <name>A0A518IYB5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Iron-sulfur cluster insertion protein ErpA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">erpA</name>
        <name evidence="2" type="ORF">Mal33_40980</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.300.12">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000361">
        <property type="entry name" value="FeS_biogenesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016092">
        <property type="entry name" value="FeS_cluster_insertion"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017870">
        <property type="entry name" value="FeS_cluster_insertion_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035903">
        <property type="entry name" value="HesB-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01521">
        <property type="entry name" value="Fe-S_biosyn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89360">
        <property type="entry name" value="SSF89360"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00049">
        <property type="entry name" value="TIGR00049"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01152">
        <property type="entry name" value="HESB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe-S_biosyn" evidence="1">
        <location>
            <begin position="1"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="110" mass="12194" checksum="54AF1ED7AD1E523B" modified="2019-10-16" version="1">MPIQLSERAAEEVKRFRTEHNFEDAMFLRIGVAGGGCSGFNYTLNFDDNFDDKADSKYESHGVAVVVDKKSALYLDGTTVDWFESLEKQGFTFENPNATKSCGCGSSFQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYJ2</accession>
    <name>A0A518IYJ2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ribosomal large subunit pseudouridine synthase D</fullName>
            <ecNumber evidence="2">5.4.99.23</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rluD_3</name>
        <name evidence="2" type="ORF">Mal33_41740</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="5.4.99.23" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120159">
        <property type="term" value="F:rRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034470">
        <property type="term" value="P:ncRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001522">
        <property type="term" value="P:pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02869">
        <property type="entry name" value="PseudoU_synth_RluA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PseudoU_synth_2" evidence="1">
        <location>
            <begin position="11"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="236" mass="26358" checksum="DC85F023FFAB175B" modified="2019-10-16" version="1">MDVIWEDNYALVVNKPNGLLTTAARGVESLEIQLLEFFKQRSGEESPYVGMPHRIDRPVSGAVLIGKTRSATKQFCAQFQSRKIEKTYVAIVSGTPTEPTGTWRDWMRKISDRAEAEIVDAEHPEAKQAILNYELLASVGDLSCLRIGLETGRTHQIRLQAAHRGFPIVGDSLYGSQIDFGPQSTEPRKRPIALHARQIVFRHPKNGKATSVLVDVPEVWRTLGFHEVLKEGELCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYL7</accession>
    <name>A0A518IYL7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NifU-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">nifU</name>
        <name evidence="2" type="ORF">Mal33_41960</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06664">
        <property type="entry name" value="IscU_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002871">
        <property type="entry name" value="NIF_FeS_clus_asmbl_NifU_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01592">
        <property type="entry name" value="NifU_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NifU_N" evidence="1">
        <location>
            <begin position="10"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="145" mass="15616" checksum="D220B4EDB59BE4B9" modified="2019-10-16" version="1">MSNSYGAIDQTLIDHFEDPYHRGDCEAATHVAEGENSLCGDTMQVQLRISPSGGQIEEAWFDGDGCVVSQAAASMLMETIEAMTPDAIRDFDTRAMLELLGPSIAVSQQKCGLLAWRVLQLALQSPLDEFGDGPTFGGPHLGEEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYX4</accession>
    <name>A0A518IYX4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glycerol uptake facilitator protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">glpF</name>
        <name evidence="7" type="ORF">Mal33_43130</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the MIP/aquaporin (TC 1.A.8) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015267">
        <property type="term" value="F:channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1080.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023271">
        <property type="entry name" value="Aquaporin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000425">
        <property type="entry name" value="MIP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00230">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00783">
        <property type="entry name" value="MINTRINSICP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81338">
        <property type="entry name" value="SSF81338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00861">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="89"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="167"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="198"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="253"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV58295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="288" mass="30045" checksum="DB29B3E09984C3CE" modified="2019-10-16" version="1">MSDRPLSACCVAEVLGTFLLIFFGCGAVHVAVLMGDLQGLWQVGIVWGISIMLAIYVVGSISGAHINPAITCGLATWGLFPWARVPAYVLSQLAGAILAAAVLFTVFQPYLAAKEKQKGVVRGQPGSELTAMCYGEYFPNPGGMAGTPDLYDATAHAEHNKLVTEPIACLIEIIGTAILALVVIAVTDSKNQAGPGNFAPVFIGLTVAALICVIAPLTQACFNPARDFGPRLFAYFAGWGSIALPGAQGTGFLTVYIISPIVGSVLGIGIYQLMLGRWVAESETPAGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ24</accession>
    <name>A0A518IZ24_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Diaminopimelate epimerase</fullName>
            <shortName evidence="8">DAP epimerase</shortName>
            <ecNumber evidence="4 8">5.1.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">PLP-independent amino acid racemase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 10" type="primary">dapF</name>
        <name evidence="10" type="ORF">Mal33_43550</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>(2S,6S)-2,6-diaminoheptanedioate = meso-2,6-diaminoheptanedioate</text>
            <dbReference type="Rhea" id="RHEA:15393"/>
            <dbReference type="ChEBI" id="CHEBI:57609"/>
            <dbReference type="ChEBI" id="CHEBI:57791"/>
            <dbReference type="EC" id="5.1.1.7"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; DL-2,6-diaminopimelate from LL-2,6-diaminopimelate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the diaminopimelate epimerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="5.1.1.7" evidence="4 8"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00025"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008837">
        <property type="term" value="F:diaminopimelate epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00197">
        <property type="entry name" value="DAP_epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018510">
        <property type="entry name" value="DAP_epimerase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001653">
        <property type="entry name" value="DAP_epimerase_DapF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31689">
        <property type="entry name" value="PTHR31689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01678">
        <property type="entry name" value="DAP_epimerase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00652">
        <property type="entry name" value="DapF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01326">
        <property type="entry name" value="DAP_EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 8 10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6 8" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="8">
        <location>
            <begin position="73"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8">
        <location>
            <begin position="213"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8">
        <location>
            <begin position="223"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="72"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8">
        <location>
            <position position="72"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="222"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="11"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="63"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="162"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Could be important to modulate the pK values of the two catalytic cysteine residues" evidence="8">
        <location>
            <position position="164"/>
        </location>
    </feature>
    <feature type="site" description="Could be important to modulate the pK values of the two catalytic cysteine residues" evidence="8">
        <location>
            <position position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV58337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="279" mass="30448" checksum="CFDDEAEEE775865C" modified="2019-10-16" version="1">MQFTKMQGAGNDYVYIDCFAQPTPENIADLAIRISDRHFGVGGDGLVLIQPSEIADARMRMFNADGSESEMCGNAIRCVAKYLYDHDIRRTPTLNIETGVGVLKLDLQAEGDRVQQVTVNMGKPILEAAEVPTTILPSGRVVDEKFEIDGHQLSVTCVSMGNPHCVCFVESATDELVLGLGPKIEVDPRFPNRTNVEFVEVISRGELRQRTWERGSGETWACGTGASAVCAAAVLSGRTDRDVLIHLLGGDLRLRWDEASGDMFKTGPAVEVFTGQWEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ71</accession>
    <name>A0A518IZ71_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_44060</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="85" mass="10094" checksum="CBE58B9F87321B7D" modified="2019-10-16" version="1">MKKHEWRETTDEGEVRLATATRHAGKWKLRSRLKSEAEWTEFPVIPLEDLRTLHDLISNKYQRQRAPYEHLLELEALIAAAEQKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZB0</accession>
    <name>A0A518IZB0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cofactor-independent phosphoglycerate mutase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Mal33_44370</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00145">
        <property type="reaction ID" value="UER00565"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046537">
        <property type="term" value="F:2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16011">
        <property type="entry name" value="iPGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023665">
        <property type="entry name" value="ApgAM_prokaryotes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006124">
        <property type="entry name" value="Metalloenzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004456">
        <property type="entry name" value="Pglycerate_mutase_ApgM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042253">
        <property type="entry name" value="Pglycerate_mutase_ApgM_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31209">
        <property type="entry name" value="PTHR31209"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01676">
        <property type="entry name" value="Metalloenzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10143">
        <property type="entry name" value="PhosphMutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006392">
        <property type="entry name" value="IPGAM_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00306">
        <property type="entry name" value="apgM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02535">
        <property type="entry name" value="hyp_Hser_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metalloenzyme" evidence="6">
        <location>
            <begin position="1"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV58419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="401" mass="42918" checksum="CB93786D4776555B" modified="2019-10-16" version="1">MKYVIIIPDGCADEALEALGGKTPLQAAQIPHMDAIAAAGTVGLSNNTPADFPAGSEVANLCLLGYDPNQYFTGRAPLEAAAQGIELGPHDWAVRCNLVTIENQTMVDFTADHITTAEATELLKSLQEKLGSDQIQFVPGVSYRNLMLFRGSAESPAPFGQETRTSAPHDLTDLPVVDDFPRGPGSDMISELMAASHEIFADHPVNVARRAAGKRPATNVWLWGQGLAPSLPPFREAYGPQGVMITAVDLLRGIAAIVGWPRIEVAGATGYLDTDYAAKGQAAIEALKEYDLVCVHIEAPDEASHEGRHDAKIEALQQIDSQIVGPLHAALQAQGEYRILVMPDHPTFCSTKKHTHGMVPFAIAGSDTKADPAQTFDEVAAASTGKSFDQGWDLMKEFTAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZB5</accession>
    <name>A0A518IZB5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_44490</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021892501" evidence="2">
        <location>
            <begin position="26"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="181"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="191"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="334" mass="36946" checksum="B3568357BD6C2624" modified="2019-10-16" version="1" precursor="true">MLRSSKTTCCLLLLLLISASGCSLVPDAIHDPQVHNPFPQLKRIAVLPFFNQSNEPTLNQDAVAEAYYGELQAILGFEVLPVGVTKLKWHEFNRQYGDSAGPDYFQRFAQYLDVDAVVVGAVTDFTPYYPPRMAMTTHWYAANPGFHPIPPGYGLPWGTPEEQDIPRDVVLETEFELARAQLKTQSPQSPAAPAPQAPYPSNDTPPAPADMTIFDPAAGDPAIAGSLPGGWPDPTGLIPDPPSVVPPPMLAQAEPVLSHTRIYRGDDSEFTQKLADTFYSDDDARFGGWQSYLSRSDDFIRFCCKLHITEMLGSRGGKHKSDLILRWPISRYER</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZS2</accession>
    <name>A0A518IZS2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">4-hydroxy-tetrahydrodipicolinate synthase</fullName>
            <ecNumber evidence="2">4.3.3.7</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">dapA_5</name>
        <name evidence="2" type="ORF">Mal33_46190</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DapA family.</text>
    </comment>
    <dbReference type="EC" id="4.3.3.7" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008840">
        <property type="term" value="F:4-hydroxy-tetrahydrodipicolinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002220">
        <property type="entry name" value="DapA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12128">
        <property type="entry name" value="PTHR12128"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00701">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001365">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01130">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR001365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="304" mass="33171" checksum="ACA06B4571EC3755" modified="2019-10-16" version="1">MPALMTPCDSVGNPDFDALVRKGQQLIDAGMCAVVYCGSMGDWPLLTDQQRQEGVRRLSEAGVPVVVGTGAQNPRLAAAHAAHAQEVGAAGLMLIPRVLSRGNSAAAQRHHFTDILRAADRLPAVIYNSPYYGFQTRADLFFELRREHPNLVGFKEFGGAESLSYAAEHITSGNPDLALMVGVDTQVFHGFVRCGAVGAITGVGNALPKQVLRLIELCRAAAAGDVDARRLALELDGAMAVLSKFDEGPDLVLYYKYLMVLEGDSEYEHHFNSYDALSDSQRALIHEQWTLFKSWWNNWPGAKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZU3</accession>
    <name>A0A518IZU3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Multidrug resistance protein MdtN</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_46410</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="15"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="487"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="188"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="514"/>
            <end position="529"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV58617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="537" mass="58722" checksum="81C06662660FA004" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZV6</accession>
    <name>A0A518IZV6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_46470</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011447">
        <property type="entry name" value="DUF1552"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07586">
        <property type="entry name" value="HXXSHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="439" mass="47911" checksum="35E09048944D5075" modified="2019-10-16" version="1">MINRRKMLMGTAAGMGAALGGPLVPNRVQAAAARPGTPRRVIFFLQNQGFDPATCIPQGLDHDASLSGITLPEPVQALEPYKDKMTIINGLHGRHTSPSHSAFFGALGGYRGGIGIPPSGATIDHELSQLLPETILPHLCIGMDALENMISRPTLATLSAAGPGKPLFMHSNPNDLYQMIFGGIATGDVKQRFEARSRVFNRVEQLAGQHGRSLPQGDRERYGSYVDGFREINGLRERLAGVSDHLKKFAPEYGDKFLKPEFETDWHDSLLDVGIATLKAGLTNVLTIGSGRGEIFGAWKGLGIAQAGHNLGHMDQPDNPIWIKIRQYNCQMLVKLMKELESVPEGDGTMMDNTLIVYTSNNANKQHTNGDNWPFILLGNCAGRLKTGQFIQMNDKRPINALYTTLLHAVGDTRDRFNMNKNTAGVHDTKVGPIEEIMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZY3</accession>
    <name>A0A518IZY3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DNA ligase</fullName>
            <ecNumber evidence="3">6.5.1.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ligA_1</name>
        <name evidence="3" type="ORF">Mal33_46770</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="6.5.1.2" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003911">
        <property type="term" value="F:DNA ligase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000551">
        <property type="entry name" value="MerR-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13411">
        <property type="entry name" value="MerR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00422">
        <property type="entry name" value="HTH_MERR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="SSF52113"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50937">
        <property type="entry name" value="HTH_MERR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH merR-type" evidence="2">
        <location>
            <begin position="135"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="432" mass="47781" checksum="8D22112DB66E2D4E" modified="2019-10-16" version="1">MTNRTPADDETADSVSALDDVNDELADDETLSPEPPSEDSPIKGKRIAFAGKLGGLSRRDAMRLIREHSGIACDQPSMAVDIVVIGAEESPLAEGDLLSDELCEAAARGEIEVLSETEFWQRLGLVEAEQAVKRLYTPAMLADLLGVSVRVIRRWHRRGLIVPARTVHKLPYFEFQEIATARRLAELLAAGASVAAIERKLESLSQVLPSVDRPLAQLSVIIEGKQLLLRQGEGLIEPGGQLRIDFDALPLEDDPEPEANPSVLAFGNSDPEPVEEEGEIDPLQQKAFDSEDDGEFEAAIDCYHAILARDGARADISFQLAELFYRMGESWAARERYLISIELDPDFVEARASLGGLLAEMGRKELAVAAFRGALRVHDDYPDVHYNLARTLDELDREIEADHHWRRFLQLAPESPWAAAARERLNLDPEPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0A1</accession>
    <name>A0A518J0A1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DsrE/DsrF-like family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_47830</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027396">
        <property type="entry name" value="DsrEFH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003787">
        <property type="entry name" value="Sulphur_relay_DsrE/F-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02635">
        <property type="entry name" value="DrsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75169">
        <property type="entry name" value="SSF75169"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021769797" evidence="2">
        <location>
            <begin position="24"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="225"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="405" mass="42655" checksum="3466FFD2B64EE01D" modified="2019-10-16" version="1" precursor="true">MKRSIPFLSILILGLLAIATASAQHQSGERRGLGFGGGRGAGLGHGKGMRRHPAADKKTAEARQLVYPVIANHGGVVHLPDAAQQPRAGTKLVVDLTSGGDPGQLNAGVEKLARYLNIYAGAGAKPAAAKIAVVFHGGATLAVLNEDAYTAKFKTASNPNLKLLRQLHDAGVELFVCGQALNGKGSAPDEVVDFIDVAVSALTAIVNLQSDGYAYIPLAGAAPKASPELDPASANESDNSKQAGPVGHGHGHGNGGKHGGGGMQGDMKTLHAMFDERSKIKRTVTNLPDGAEAVTESDDEAVTLMIQNHVAAMEERVLGNKPLPPMTFHPIFVALLKHADDYTFTYTPTEKGIRVKYQSDNPYVVMLVQEHAKLISRFIKNGMAEVHAPYTLPTSVQEPNADGRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0B1</accession>
    <name>A0A518J0B1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Threonine--tRNA ligase</fullName>
            <ecNumber evidence="9">6.1.1.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Threonyl-tRNA synthetase</fullName>
            <shortName evidence="9">ThrRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9 12" type="primary">thrS</name>
        <name evidence="12" type="ORF">Mal33_47930</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>ATP + L-threonine + tRNA(Thr) = AMP + diphosphate + H(+) + L-threonyl-tRNA(Thr)</text>
            <dbReference type="Rhea" id="RHEA:24624"/>
            <dbReference type="Rhea" id="RHEA-COMP:9670"/>
            <dbReference type="Rhea" id="RHEA-COMP:9704"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78534"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.3" evidence="9"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004829">
        <property type="term" value="F:threonine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006435">
        <property type="term" value="P:threonyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00771">
        <property type="entry name" value="ThrRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00184">
        <property type="entry name" value="Thr_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004095">
        <property type="entry name" value="TGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012676">
        <property type="entry name" value="TGS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002320">
        <property type="entry name" value="Thr-tRNA-ligase_IIa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018163">
        <property type="entry name" value="Thr/Ala-tRNA-synth_IIc_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033728">
        <property type="entry name" value="ThrRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012947">
        <property type="entry name" value="tRNA_SAD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11451">
        <property type="entry name" value="PTHR11451"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02824">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07973">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01047">
        <property type="entry name" value="TRNASYNTHTHR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00863">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55186">
        <property type="entry name" value="SSF55186"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81271">
        <property type="entry name" value="SSF81271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00418">
        <property type="entry name" value="thrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51880">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 9 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 9" id="KW-0820">tRNA-binding</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="TGS" evidence="11">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="10">
        <location>
            <begin position="276"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="402"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="453"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="582"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QDV58768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="729" mass="81764" checksum="2E324BF2C083AEDF" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0D4</accession>
    <name>A0A518J0D4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_47900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010869">
        <property type="entry name" value="DUF1501"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07394">
        <property type="entry name" value="DUF1501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="493" mass="54183" checksum="2A6126563CC34B6B" modified="2019-10-16" version="1">MTDSLQNEIGLKQSQLTTRRALLGGSVTGIGAMALNQLLANESPAAAAETDVSPGLPGLPHFAPKAKRVIYLFQSGGPSHIDLFDHKESLDKLHGTDLPDSIRGDQRLTGMTSWQKSFPVVKPLWGGKRCGEHGTWIGNPLPHTQTIADEISIVRSMWTEAINHDPAVTYINTGSQQIGHASMGSWLSYGLGSENEDFPAYMVLLSQGTGKNPGQPLFSRLWGSGYLPSSHQGVMLRPGANPVLYLQNPAGVSRDSRRNLLDTLGQLNQMHWDSSGDPETLARIEAYEMAYRMQTSVPDLTDVSDEPESTFELYGEDSRRPGTFAANCLLARRMAEHGVRFIQLFHRGWDQHVSLEHQLPRQCKDVDQASAALVKDLKRLGMLKDTLVVWGGEFGRTVYSQGELGNPSSGRDHHGRCFTTWMAGGGVKAGFDYGTTDEFAYNIVENPVHIRDLNATILHLLGIDHSRFTFKFRGLSQRLTGVEEAHVVDGLVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0Q1</accession>
    <name>A0A518J0Q1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Succinate--CoA ligase [ADP-forming] subunit beta</fullName>
            <ecNumber evidence="6">6.2.1.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Succinyl-CoA synthetase subunit beta</fullName>
            <shortName evidence="6">SCS-beta</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 9" type="primary">sucC</name>
        <name evidence="9" type="ORF">Mal33_49460</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>ATP + CoA + succinate = ADP + phosphate + succinyl-CoA</text>
            <dbReference type="Rhea" id="RHEA:17661"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.2.1.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="6">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Carbohydrate metabolism; tricarboxylic acid cycle; succinate from succinyl-CoA (ligase route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Heterotetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the succinate/malate CoA ligase beta subunit family.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.5" evidence="6"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00223">
        <property type="reaction ID" value="UER00999"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004775">
        <property type="term" value="F:succinate-CoA ligase (ADP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.261">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00558">
        <property type="entry name" value="Succ_CoA_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013650">
        <property type="entry name" value="ATP-grasp_succ-CoA_synth-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005811">
        <property type="entry name" value="CoA_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017866">
        <property type="entry name" value="Succ-CoA_synthase_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005809">
        <property type="entry name" value="Succ_CoA_synthase_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016102">
        <property type="entry name" value="Succinyl-CoA_synth-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11815">
        <property type="entry name" value="PTHR11815"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08442">
        <property type="entry name" value="ATP-grasp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00549">
        <property type="entry name" value="Ligase_CoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001554">
        <property type="entry name" value="SucCS_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52210">
        <property type="entry name" value="SSF52210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01016">
        <property type="entry name" value="sucCoAbeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01217">
        <property type="entry name" value="SUCCINYL_COA_LIG_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 6 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 6" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="ATP-grasp" evidence="8">
        <location>
            <begin position="9"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding; shared with subunit alpha" evidence="6">
        <location>
            <begin position="329"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="46"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="53"/>
            <end position="55"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="107"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="207"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="221"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="272"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared with subunit alpha</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV58921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="395" mass="42270" checksum="500C82BE3E2EE892" modified="2019-10-16" version="1">MKIHEYQAKELFRAAGVPVLQGMVARNADEAKDAYNKLGGAIAVVKAQIHAGGRGKGTVTEKPEQHGVELVKSADDAARVAENLLGNHLVTIQTGPEGQRVNQVFVESGCNIARELYLGIVLDRAVSLPVLMVSTEGGMEIEKVAEETPEKILKEHFDPHVGLESYQVRKLCKAMGISGKAARSADLFMKKICQLYVDLDCALLEVNPLVITGDDEMIALDAKVTFDDNAMFRHKDIAELRDDAEEEPSELRAAASGLSFVKLDGNIACLVNGAGLAMSTMDIIKHHGGEPANFLDVGGGANKDQVTEAFRILLADPHVKAVLVNIFGGIARCTTIADALIAASKEVGFNVPLVVRLEGTEVEEGRRMLEESDVEIINAVGLTDAAKKVVEAAGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0T2</accession>
    <name>A0A518J0T2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">RNA polymerase sigma factor SigL</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_49670</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
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    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011517">
        <property type="entry name" value="RNA_pol_sigma70_ECF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07638">
        <property type="entry name" value="Sigma70_ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02999">
        <property type="entry name" value="Sig-70_X6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="187" mass="21010" checksum="8F3C3F2E57CFCC4C" modified="2019-10-16" version="1">MNSDVTNILEAIESGDQQAAEQLLPIVYQELRRLAASRMTREKAGHTLQPTALVHEAFMRLVGGTDRQKWSGREHFFAAAAESMRRILIESARRRNAEKRGGGMVRADLGENDAAVCPQDDETLLALNEALIKLQDHDARLAKLVELRYFTGMTIDETAAVLGVSSRTVKRNWTYARAWLRNQMDGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J129</accession>
    <name>A0A518J129_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_11310</name>
        <name evidence="2" type="ORF">Mal33_50690</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="99" mass="11518" checksum="DC67FC461EE366CF" modified="2019-10-16" version="1">MMRADISYDLVLDEDMEFLEGTYRLPGQDWQVFVVSAFRRDVPDAQIVPQRWQSGVTGVLLRIPEAEKINARVVERLLSEGFHVSEWIRVRGPDSMQLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J157</accession>
    <name>A0A518J157_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl hydrolase family 92</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_50950</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041371">
        <property type="entry name" value="GH92_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012939">
        <property type="entry name" value="Glyco_hydro_92"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07971">
        <property type="entry name" value="Glyco_hydro_92"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17678">
        <property type="entry name" value="Glyco_hydro_92N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_hydro_92N" evidence="2">
        <location>
            <begin position="22"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_92" evidence="1">
        <location>
            <begin position="306"/>
            <end position="728"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV59070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="747" mass="82782" checksum="BFA68C807E962450" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1A2</accession>
    <name>A0A518J1A2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_51380</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="53" mass="5844" checksum="A566D3A4F969A0B7" modified="2019-10-16" version="1">MPTTRPEADGLRAKLVSGFGNYVVLYFVTSETIDIARVVWGGQEIDQIALNCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1M6</accession>
    <name>A0A518J1M6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATPase family associated with various cellular activities (AAA)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_52660</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011703">
        <property type="entry name" value="ATPase_AAA-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041628">
        <property type="entry name" value="ChlI/MoxR_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07726">
        <property type="entry name" value="AAA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17863">
        <property type="entry name" value="AAA_lid_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_3" evidence="1">
        <location>
            <begin position="37"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="AAA_lid_2" evidence="2">
        <location>
            <begin position="247"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV59238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="319" mass="34881" checksum="2099F4AF219B41A9" modified="2019-10-16" version="1">MEPREAILKISAAMNAAVIGQQEVVERILIALLADGHVLMEGFPGTAKTRSVKTLSKLVESDFGRVQFTPDLLPSDVTGSEIYREQDGSFEFQPGPIFGNLILADEINRAPAKVQSALLEAMEERQVTVAAKTHALPELFLVLATQNPIEQEGTYPLPEAQMDRFLLYVRVDYPVGENETAILRLVRGEKSGAAAEPIAPLSQEVIFAARKEVYAVHVAEPAEKYIVDLILATRNSKQYGDQLARWIRLGASPRGTLALDAAARAHAWLQGQDFVSPDNIRAVAAACLAHRIHLTYEAEAAGVTRVEVIEELLKNVVPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1N5</accession>
    <name>A0A518J1N5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Inositol 2-dehydrogenase</fullName>
            <ecNumber evidence="2">1.1.1.18</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">iolG_18</name>
        <name evidence="2" type="ORF">Mal33_52690</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.1.18" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050112">
        <property type="term" value="F:inositol 2-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GFO_IDH_MocA" evidence="1">
        <location>
            <begin position="31"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="429" mass="47184" checksum="BC1C9CBA1CCE6E97" modified="2019-10-16" version="1">MQSSSLLLAGGAVAGGLSVARAAHSFGSDTIRVGLIGCGGRGTGAVTQALSTVDGEVRLTAMGDLFEDRMQTAFRTIKSKHPDRVDVTRDTRFVGFDAYQKVLQADVDVVILATPPGFRPLHFEAAVDAGKHVFMEKPVATDAPGVRRVLAANAIAKHNGLAVSVGLQRHHEARYRQCVAQLHAGMIGDVIMSRAYWNGSGIWVRPRQQNDTELQYQCRNWYYFNWLCGDHITEQHVHNLDVINWVMDGFPVDAQGQGGRQVRTGEDTGQIFDHHFVEYTYDGGAKLISQCRHMKGCWNSVGEYVHGTRGYAIVNKAEIYDHQDNLIWKSDAAVEQGKGWQQQHHDLFAALRRGESPNEADYGAHSTMTAIMGRMATYGGKVVRWDDAIHSDIALADFDSLRSWDDVPPVLPADDGSYPVAVPGKTIVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1W8</accession>
    <name>A0A518J1W8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Decarbamoylnovobiocin carbamoyltransferase</fullName>
            <ecNumber evidence="4">2.1.3.12</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">novN_2</name>
        <name evidence="4" type="ORF">Mal33_53600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NodU/CmcH family.</text>
    </comment>
    <dbReference type="EC" id="2.1.3.12" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.870.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
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        <property type="entry name" value="Carbam_trans_C"/>
    </dbReference>
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        <property type="entry name" value="Carbam_trans_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003696">
        <property type="entry name" value="Carbtransf_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16861">
        <property type="entry name" value="Carbam_trans_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02543">
        <property type="entry name" value="Carbam_trans_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Carbam_trans_N" evidence="2">
        <location>
            <begin position="26"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="domain" description="Carbam_trans_C" evidence="3">
        <location>
            <begin position="430"/>
            <end position="596"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV59332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="613" mass="68621" checksum="97121D3A5F5230CC" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1X7</accession>
    <name>A0A518J1X7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DDE_Tnp_1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_53640</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002559">
        <property type="entry name" value="Transposase_11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01609">
        <property type="entry name" value="DDE_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_1" evidence="1">
        <location>
            <begin position="23"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="131" mass="14819" checksum="08E1D86C7968A14F" modified="2019-10-16" version="1">MIETSNRLVGHVDWPGFAQAIRLTRTRILGGERQTEISYAITSVDRERADARDLLKFVRGHWGIENRLHWVRDVAMGEDKCRARTGAIPQNLAALRNATLTLVRAKGHNAITSTLRRLATKPMEIISILKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J245</accession>
    <name>A0A518J245_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF5615 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_54470</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041049">
        <property type="entry name" value="DUF5615"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18480">
        <property type="entry name" value="DUF5615"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF5615" evidence="1">
        <location>
            <begin position="7"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="134" mass="14960" checksum="29587EDFACA2C191" modified="2019-10-16" version="1">MKLNDCRLLADENLHSRVVESLRAMEMDVQSVREEGWSGKPDGELLQLAVEDKRVVVTHDSDFGALAIRRRQAVYGILYLRPGHMQPAKTIALAQSVLRQAIDVTPPFIVVAHCAGEDVTIRVRELARESEGTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J275</accession>
    <name>A0A518J275_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Choline-sulfatase</fullName>
            <ecNumber evidence="4">3.1.6.6</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">betC_10</name>
        <name evidence="4" type="ORF">Mal33_54660</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="PTM">
        <text evidence="1">The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.</text>
    </comment>
    <dbReference type="EC" id="3.1.6.6" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047753">
        <property type="term" value="F:choline-sulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021762536" evidence="2">
        <location>
            <begin position="26"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase" evidence="3">
        <location>
            <begin position="30"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="modified residue" description="3-oxoalanine (Cys)" evidence="1">
        <location>
            <position position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR600917-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV59431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="473" mass="53187" checksum="0D21D910A98D57A5" modified="2019-10-16" version="1" precursor="true">MNRLQRIACAIACLLSVCCSPAAFADDRPPNVVVVFIDDMGYADPSCFGNPAMKTPNIDRLAAEGIRLTNFYVNSPICSASRVALTTGQYQQRYRIHSYFATRESNRQRKMPDWLDPTAPTLAKLLKSAGYATAHFGKWHMGGGRDVGDAPLPQAYGFDESLVSFEGLGDRILWQKTGNQEQSWKHGRGKILDLPKHKTTETYVDHAIDFMTKNRDQRFYLRVFPNDVHDRHLPSDEQRKKWEGASDNPPDVDFFAVLDETDRQIGRLLNTIDALELADDTLVLFTSDNGPTDWPRYYKDGHQPPGFTGPLRGRKWSLYEGGIRMPFIARWPGKIPAGATNDQTVMAAIDVLPTIAKLCGAGVDMDRADGLDMSAALLGKPTVRNRPIFWEYGVHGSIKPGTPENISPQLAMRQDDWKLLCNPDGSELKLFDLANDIGETENVAANHQQRTAEMQTQLLQWWSEMNTYYETKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J284</accession>
    <name>A0A518J284_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Zeta toxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_54830</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="199" mass="22495" checksum="DD30FE1B9E601173" modified="2019-10-16" version="1">MIESQKPTVYVIAGPNGAGKTTFAQEYLLKHANCDEFVNADLIAAGLSPYKPESQSVAAGRLMLDRIDELTSAKQIFAFETTLAGRGHVKRLRRMRNKQGYRIVVFFIWLPSVEQAVARVAARVREGGHAIPEPTIRRRYRLGIQNFGQLYAPFVDHWLVYDGSSRPAVIVVEQNDATNTVFDDDRYEFILQRTPELLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J2E1</accession>
    <name>A0A518J2E1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_55380</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="158" mass="17348" checksum="DFD40E9578520E53" modified="2019-10-16" version="1">MHGTDVLSVETRSIRIPRVAMAVRLLFALFLLSTGIMTIGFAINGYPVGDSPGDVGRFMMALEKTGYLIFWVGFFKAVVGGLMFVPRTAPLAVLMSLPYAFNILLYVTLFAHQYLVVGLPDFAACTLLLYCYFDWYRPIFAGQTTAPIQVSCGDGNAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ILY8</accession>
    <name>A0A518ILY8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">FG-GAP repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_00580</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.130">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013517">
        <property type="entry name" value="FG-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028994">
        <property type="entry name" value="Integrin_alpha_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011040">
        <property type="entry name" value="Sialidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036278">
        <property type="entry name" value="Sialidase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13088">
        <property type="entry name" value="BNR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13517">
        <property type="entry name" value="FG-GAP_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50939">
        <property type="entry name" value="SSF50939"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69318">
        <property type="entry name" value="SSF69318"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022034555" evidence="2">
        <location>
            <begin position="23"/>
            <end position="1005"/>
        </location>
    </feature>
    <feature type="domain" description="Sialidase" evidence="3">
        <location>
            <begin position="694"/>
            <end position="972"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV54116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1005" mass="111162" checksum="E599B452697B0DA5" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMT6</accession>
    <name>A0A518IMT6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Primosomal protein N'</fullName>
            <ecNumber evidence="9">3.6.4.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">ATP-dependent helicase PriA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9 12" type="primary">priA</name>
        <name evidence="12" type="ORF">Mal33_03490</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the primosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the helicase family. PriA subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.-" evidence="9"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990077">
        <property type="term" value="C:primosome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006269">
        <property type="term" value="P:DNA replication, synthesis of RNA primer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006268">
        <property type="term" value="P:DNA unwinding involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1440.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00983">
        <property type="entry name" value="PriA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005259">
        <property type="entry name" value="PriA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041222">
        <property type="entry name" value="PriA_3primeBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042115">
        <property type="entry name" value="PriA_3primeBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041236">
        <property type="entry name" value="PriA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040498">
        <property type="entry name" value="PriA_CRR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17764">
        <property type="entry name" value="PriA_3primeBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18074">
        <property type="entry name" value="PriA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18319">
        <property type="entry name" value="PriA_CRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00595">
        <property type="entry name" value="priA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 9" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8 9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 9" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 9 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1 9" id="KW-0639">Primosome</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
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            <end position="444"/>
        </location>
    </feature>
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        <location>
            <begin position="540"/>
            <end position="706"/>
        </location>
    </feature>
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        <location>
            <begin position="505"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C4-type" evidence="9">
        <location>
            <begin position="532"/>
            <end position="548"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QDV54395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="800" mass="88289" checksum="508FDAC211291276" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMT9</accession>
    <name>A0A518IMT9_9BACT</name>
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        <submittedName>
            <fullName evidence="2">BON domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_03560</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">Mal33</strain>
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    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="BON"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="11"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="79" mass="8906" checksum="91899600CDF8DC80" modified="2019-10-16" version="1">MTTQTLPAQHDIEPLQIRVDSVIRQHPHLRGMGIRPHADGQNVVLSGTVRSYFIKQMAQEAVRSVPGADQVDNQIEVHW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMU9</accession>
    <name>A0A518IMU9_9BACT</name>
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        <submittedName>
            <fullName evidence="3">ECF RNA polymerase sigma factor SigW</fullName>
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    </protein>
    <gene>
        <name evidence="3" type="primary">sigW_2</name>
        <name evidence="3" type="ORF">Mal33_03590</name>
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    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
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            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 4">Mal33</strain>
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    </reference>
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        <property type="protein sequence ID" value="QDV54405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="component" value="Chromosome"/>
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    <dbReference type="GO" id="GO:0003700">
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        <property type="project" value="InterPro"/>
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        <property type="project" value="InterPro"/>
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        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
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        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="PTHR43133"/>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="2">
        <location>
            <begin position="32"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="191" mass="21361" checksum="0A751CD583A5D502" modified="2019-10-16" version="1">MSTAFQSDLRNQTVAELVTAAQAGDRLAFGELFDRYRPQVIGLAIRRLGSVDEAEELAQDVFVQAMQKIDQLRVPEAFGGWVRQIVHRMAINRFTRRPRAVACDPVTLDATCFDSGTPEDVAIDRENAAYIHEGLGRLGDMDRQTLEAFYLDGQSLIEMSDAFDAPVGTIKRRLHVARKRLAKELDVLQAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMX4</accession>
    <name>A0A518IMX4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_04000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022044139" evidence="1">
        <location>
            <begin position="25"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="147" mass="15624" checksum="0E2D1FA05F806A69" modified="2019-10-16" version="1" precursor="true">MIQSPTRISTFAAATLLLIPSLTALVGCGTSDAGPGKYSVTGTVTFEGQPLPEGEILFAPDTASGNKGPASVAYVKDGKFSTQPGMGLVGGAYTLEVTGFQTKAEMDQDGEPIVEPLFDTFVTKHEFEHQDSTYDFAVEPSEKKKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IN08</accession>
    <name>A0A518IN08_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Endonuclease/Exonuclease/phosphatase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_04240</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="SSF56219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="3" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022173600" evidence="1">
        <location>
            <begin position="38"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="domain" description="Endo/exonuclease/phosphatase" evidence="2">
        <location>
            <begin position="43"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="305" mass="34369" checksum="5B870331CD2AE3CC" modified="2019-10-16" version="1" precursor="true">MTLSRRRSSCFYCAAFLPLVLLWSTLVSLSASPVAIADDVRVMSFNIRYGTASDGENHWERRKEFVAETIAAYDPDLLGTQETLEFQKQFLEQQMPDYTSVGVGRDDGSDKGEMTALFFKTERFELRDEGHFWLSETPGKAGSKSWDSSLPRICSWVRLKDRQSDAPREILFINTHFDHRGQQARNESAALVMRKIDELGANCDVVLTGDFNSSVTSVPYRTLFADAAESSRLVDTFAVAGTKETKGDTTISRFLSDQFAGPRIDWIATRGNWKILDAQIDRTAKEGRAPSDHYPITARLQRDGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IN23</accession>
    <name>A0A518IN23_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_04260</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021789920" evidence="1">
        <location>
            <begin position="25"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="391" mass="41766" checksum="7BCBEAFF806A5F66" modified="2019-10-16" version="1" precursor="true">MTVFRIACCCVVALLFCLSRDAVAHEGHDHGTSKKNGSAPVDAMQNTFEANGKSYVWKHRPDLGKQSEAMVAAAKGGLHNNADRDSSTGEIVTVVAKHGLVTLDPEMKEWTLVEGQDPLFAAGMNAHGTDCFMIEDQSYWAFSSTNTGSVVVSQRGKVIAQLTQPKGDEFDNPTVNAYFAAGGRFTPCDVVYLPVAKRLVVVIGYAPGDFALSAEIRDGKWQWGGPAWGGKEQVGGVFSTAHGVQVATEAGQEIVEVASRSHGRVFAFTSSGAQIKMPGADAKYYLDLPKGSTPCNISHIGSSMFLPLLNPLASTKGLAPLLVMDGGKPSGMLVPATYETLGYMHHMHGFCPVERDGTLYGVVLSWPNGRENAAGKRNDGQIAIFEAVEQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IN25</accession>
    <name>A0A518IN25_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_04500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="49" mass="5734" checksum="448A95BDB6A9009F" modified="2019-10-16" version="1">MPHPSDMPANRCHWPSLHARPAYEYVPEGIETVQAFPLFRTHDERAKFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IN72</accession>
    <name>A0A518IN72_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_04860</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="50" mass="5323" checksum="CDC4B47BD26FA681" modified="2019-10-16" version="1">MSSSSGAPPDSAGEEFLSPPPALPRSENHGFNLRYQPPRVSVRLSKGTGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INC3</accession>
    <name>A0A518INC3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Lipid-A-disaccharide synthase</fullName>
            <ecNumber evidence="2">2.4.1.182</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Mal33_05530</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a lipid X + a UDP-2-N,3-O-bis[(3R)-3-hydroxyacyl]-alpha-D-glucosamine = a lipid A disaccharide + H(+) + UDP</text>
            <dbReference type="Rhea" id="RHEA:67828"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:137748"/>
            <dbReference type="ChEBI" id="CHEBI:176338"/>
            <dbReference type="ChEBI" id="CHEBI:176343"/>
            <dbReference type="EC" id="2.4.1.182"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.4.1.182" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008915">
        <property type="term" value="F:lipid-A-disaccharide synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003835">
        <property type="entry name" value="Glyco_trans_19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30372">
        <property type="entry name" value="PTHR30372"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02684">
        <property type="entry name" value="LpxB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00215">
        <property type="entry name" value="lpxB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 10" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-0441">Lipid A biosynthesis</keyword>
    <keyword evidence="4" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00029342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV54598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="427" mass="48246" checksum="6E4879AC994ED7CB" modified="2019-10-16" version="1">MMLATRFVLTNFSAANTCVYLGRSLLQPYHAPMNRSIFFSAGEPSGDQHSARLIDALRARDPQLRFRGFGGNEMEQAGCQIDFELTQLAVMGVVEVAPKIAEFYRVAQQAKQIFAQEPPQAVVLVDFPGFNWHIAKRAKACGIPVYYYLPPQLWAWAPWRLRKVRKYVDKVLCVLPFEYNWYRDRGIDAEYVGHPFFDAVAKQRLDRPTIERFDQLKADGKRLVAVLPGSRRGEVTNNWPLQLEAIRRLTKRHPDVRFQVACFRDRQCLWCREQLTAEDQSLPLDFFVGKTSEIVEAAESAIMVSGSVSLELMARSTPAVVLYRVGRILKALASVLVSTKSMTLPNLIAEKTLFPEFVSAGDPEPVIREVVAAADRMLSEPEYLADLQQQLQTLRSKYAAPGASERAAAELIELMGDHRETPIRRAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INR9</accession>
    <name>A0A518INR9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Trehalose utilization</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_06990</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029010">
        <property type="entry name" value="ThuA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06283">
        <property type="entry name" value="ThuA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022232030" evidence="1">
        <location>
            <begin position="24"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="ThuA" evidence="2">
        <location>
            <begin position="29"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="251" mass="28047" checksum="F7E415F56C5645CC" modified="2019-10-16" version="1" precursor="true">MRLSSIASVLFLCLLFVSGRATAAEPLRALLVTGGCCHDYENQIKILQAGLGKHLDIDWTVEQYDEKRDRKANVYTKPKWAESFDVIIHNECFGGVTDGEFVESIVAEHVRSGVPAVVIHCSMHSYRNAPTADAWRGLIGVTSKRHEKAKRSLKVVAREAEHPILEGFPSPWSTPNGELYIIERSWPNTQVLASAYSDEEKADQPVVWTNQYKGVRVFGTTLGHHNETMQDDVWLNLTAKGIQWATTADAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INU7</accession>
    <name>A0A518INU7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative major pilin subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_06920</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011453">
        <property type="entry name" value="DUF1559"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07596">
        <property type="entry name" value="SBP_bac_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="340" mass="36340" checksum="D4B3F8EA3E447C24" modified="2019-10-16" version="1">MKRKGFTLVELLVVIAIIGILVGLLLPAVQAAREAARRMQCSNNLKQQALAMHNYHDTYKKLPPMYIHDTAVTDDGGHWAWSSFLLPFIEQQPRYDALEVGTAKARVKITTNPELFQAPIDGYRCPSSSGPDVHVPGTDPGYCIDDTSQNNTGLAVTNYIVVSNIANLRMKRASNMTDGLTGAIGIFSRGIGREPTAGLSDILDGTSNTLMIGERFHTRAGGIRMSGGTMLVVRDNVDKGPTAHDNPGNSHWNQGIMTLAGSVRYPINVVMTPSENASSEKKMAFSSLHPGGAQFAAADGSVKFISDTVELSNGNNGGGWTVDSVLEALIGMQDGVPASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP23</accession>
    <name>A0A518IP23_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tRNA pseudouridine synthase A</fullName>
            <ecNumber evidence="4">5.4.99.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">tRNA pseudouridine(38-40) synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">tRNA pseudouridylate synthase I</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">tRNA-uridine isomerase I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4 9" type="primary">truA</name>
        <name evidence="9" type="ORF">Mal33_07830</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4 7">
            <text>uridine(38/39/40) in tRNA = pseudouridine(38/39/40) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:22376"/>
            <dbReference type="Rhea" id="RHEA-COMP:10085"/>
            <dbReference type="Rhea" id="RHEA-COMP:10087"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="EC" id="5.4.99.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 7">Belongs to the tRNA pseudouridine synthase TruA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.12" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106029">
        <property type="term" value="F:tRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031119">
        <property type="term" value="P:tRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02570">
        <property type="entry name" value="PseudoU_synth_EcTruA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.660">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00171">
        <property type="entry name" value="TruA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001406">
        <property type="entry name" value="PsdUridine_synth_TruA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020097">
        <property type="entry name" value="PsdUridine_synth_TruA_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020095">
        <property type="entry name" value="PsdUridine_synth_TruA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020094">
        <property type="entry name" value="TruA/RsuA/RluB/E/F_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11142">
        <property type="entry name" value="PTHR11142"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01416">
        <property type="entry name" value="PseudoU_synth_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001430">
        <property type="entry name" value="tRNA_psdUrid_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00071">
        <property type="entry name" value="hisT_truA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4 7" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="PseudoU_synth_1" evidence="8">
        <location>
            <begin position="12"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="domain" description="PseudoU_synth_1" evidence="8">
        <location>
            <begin position="145"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4 5">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4 6">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001430-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001430-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV54818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="260" mass="28858" checksum="C45953076076C042" modified="2019-10-16" version="1">MLRTFRLTIGYDGFRYAGWQVQADLPTIQGELQRAFAELTGERVSITGSGRTDSGVHAIAQVASLTTDAWRSSDAALGRAINTKIPDDITVYCCEEMPVDFHALRDAVGKRYRYQMQIGGVRDAFDFRYFWHHHVQLDIEAMRQAAAMIVGTHDFACFQATGSERKTTVRTIHDLALTTGQGRAGQGHLIVEVEANGFLYNMVRNIVGSLVEVGRGKHPPTWIEELIAGRDRNQAGPTAPAHALFLLRVDYDVQPLAAQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPK3</accession>
    <name>A0A518IPK3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Alpha-1,4 glucan phosphorylase</fullName>
            <ecNumber evidence="10">2.4.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">malP_2</name>
        <name evidence="11" type="ORF">Mal33_09940</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.</text>
    </comment>
    <comment type="function">
        <text evidence="8">Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>[(1-&gt;4)-alpha-D-glucosyl](n) + phosphate = [(1-&gt;4)-alpha-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:41732"/>
            <dbReference type="Rhea" id="RHEA-COMP:9584"/>
            <dbReference type="Rhea" id="RHEA-COMP:9586"/>
            <dbReference type="ChEBI" id="CHEBI:15444"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="EC" id="2.4.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 10">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the glycogen phosphorylase family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.1" evidence="10"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008184">
        <property type="term" value="F:glycogen phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102250">
        <property type="term" value="F:linear malto-oligosaccharide phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102499">
        <property type="term" value="F:SHG alpha-glucan phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011833">
        <property type="entry name" value="Glycg_phsphrylas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000811">
        <property type="entry name" value="Glyco_trans_35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035090">
        <property type="entry name" value="Pyridoxal_P_attach_site"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11468">
        <property type="entry name" value="PTHR11468"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00343">
        <property type="entry name" value="Phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000460">
        <property type="entry name" value="Pprylas_GlgP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02093">
        <property type="entry name" value="P_ylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00102">
        <property type="entry name" value="PHOSPHORYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4 10 11" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6 9 10" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10 11" id="KW-0808">Transferase</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="9">
        <location>
            <position position="668"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000460-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QDV55026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="819" mass="93225" checksum="16B8BFC924C3D3A9" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPX3</accession>
    <name>A0A518IPX3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_11140</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="437" mass="48317" checksum="674CA2A1D9239F9B" modified="2019-10-16" version="1">MLFDNPTIVAGFSPPRIGAALALCLFVAPFAAAQTRQFSGRHVTIHTDLPASAALDQLPAAFDAAVPQWCEFFGVDPDRLADWHVTAYLMTSRDAFKQRGLLPDHLPDFAHGYQYGNSVWVVDQPSDYYTRHLLLHEGVHALMFQLFGGAGPAWYMEGMAELLATHRWSDGEIALPVIPESREAFPFWGRLKVIQSARDKGQALPIDAVMRYSHKAHRQVEPYAWSWGALTLLNMYPEYRTAAIAATDRAGQPPLQFTRNFYSELKDQWPQLQLRWRMLVDGLDYGFDPLRNRIDLTNFPATAEASTATKQLEIAADRGWQSSGIRVAAGQSVRITAEGRYTLGDDPRPWECEPQGVTIQYHRGHPLGMLLAAVAPTSDADATRMTNPQIVGVGREGTFVAEFDGLLLLRIGDDPASLADNRGSASVTVSVAAAERP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQ64</accession>
    <name>A0A518IQ64_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">UDP-2,3-diacetamido-2,3-dideoxy-D-glucuronate 2-epimerase</fullName>
            <ecNumber evidence="3">5.1.3.23</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">wbpI</name>
        <name evidence="3" type="ORF">Mal33_11820</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UDP-N-acetylglucosamine 2-epimerase family.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.23" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008761">
        <property type="term" value="F:UDP-N-acetylglucosamine 2-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003331">
        <property type="entry name" value="UDP_GlcNAc_Epimerase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029767">
        <property type="entry name" value="WecB-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43174">
        <property type="entry name" value="PTHR43174"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02350">
        <property type="entry name" value="Epimerase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00236">
        <property type="entry name" value="wecB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase_2" evidence="2">
        <location>
            <begin position="28"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="370" mass="40299" checksum="251BE3BA6954271E" modified="2019-10-16" version="1">MLTVDIIAGARPNFMKIAPIVHAIDADQSSIEYRLIHTGQHYDAKMSGDFFTQLGIPEPHYNLGAGSGSQAEQTGAIMRGYEQVLQTKPSDLCLVVGDVTSTMACAIVAKKAGIDVAHVEAGIRSGDRTMPEEINRLVTDAITDYFFTTSAKANESLRTAGIDDSAIFFVGNTMIDTLLKNIDRLRKPDFFDEQSLISGNYIVITLHRPANVDKPENLATMLNAIAESANGLPVIFPVHPRTRKNLEQLPQLPECIHVVDPQPYLQFIYLVKNAKAVLTDSGGITEETTVLGVPCMTLRDSTERPETVTMGTNELIGTSVSNIPPAMQRLLAGQWKSGQVPPKWDGKTGARIVEILKQLQVASQTRTNAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQC6</accession>
    <name>A0A518IQC6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_12710</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021888224" evidence="1">
        <location>
            <begin position="23"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="191" mass="21214" checksum="A6F570FBD08BE016" modified="2019-10-16" version="1" precursor="true">MNRKGSQTLLTLLAALAAVSSAGCFGVNSGATLGIFGFPIPVSPYYQHRQEEKFWEHERYARVPILGPITSGGPPIALDPPSDDEIMMALEKARPIQGGIPLLFERQRNNVRIIKEKIADYVDPPRVMPLVGPVQLHHAHYKCTVYFSERTIVGYPVPHTLEDQDSVEVIYVDHNHLHMVGDVDPATVPEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQE4</accession>
    <name>A0A518IQE4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_12860</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="100" mass="11440" checksum="6ED142D0815850A7" modified="2019-10-16" version="1">MAKSRGSNLKRARDEADAFEAKEAEAPVKKKAKAKRKTKKKVAVEARMKLYWGVFSQSLKRVAVFEFDQKEEAEKRCKELGKGGKSPHFVQKVKEEIVEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQG5</accession>
    <name>A0A518IQG5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">1,5-anhydro-D-fructose reductase</fullName>
            <ecNumber evidence="2">1.1.1.292</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">afr_2</name>
        <name evidence="2" type="ORF">Mal33_12980</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.1.292" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033712">
        <property type="term" value="F:1,5-anhydro-D-fructose reductase (1,5-anhydro-D-mannitol-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GFO_IDH_MocA" evidence="1">
        <location>
            <begin position="32"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="349" mass="38748" checksum="D2FA65535C4FCD02" modified="2019-10-16" version="1">MPRRDRVSPFLFVALFAQTAWFADRIFRLNALRFGVLGTARIARRIVADMQSVDAIQVVGIASRDPARARWYADQYGIAQAFDSYDAMLASDSIDAIYIPLPPSLHHDWALAAADAGKHLIVEKPVAMTLAEAQAIDQRCRDRGRQWLDATAWLHHLRTDRIRQSIDAGELGRVQHISVACSFFEPFQSDDHRLKPDLGGGCLLDLGWYAYGMARWAAGRLPVAVQSIGRQDRGIWFRSSSLLDFGDDLTATVNCAYDTATRKWFEIAGDQASIVCDDFTRPWPSKPARFWIHDRAGSAKSETFDGNQEARMLATFADLVSNATAAAAMNQQALDTQQILQTVADGIAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQH1</accession>
    <name>A0A518IQH1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Planctomycete cytochrome C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_12810</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011429">
        <property type="entry name" value="Cyt_c_Planctomycete-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07635">
        <property type="entry name" value="PSCyt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021750627" evidence="2">
        <location>
            <begin position="24"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="167"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="197"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="237"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="267"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="domain" description="PSCyt1" evidence="3">
        <location>
            <begin position="48"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV55310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="325" mass="35052" checksum="C716B8B7F8344A9A" modified="2019-10-16" version="1" precursor="true">MKTNKFLGIVFCLAFLSSSAAIAAGPLNADGQVIDFQRDVAPILRTKCLSCHGPDDAKNDFRVDDPEIMADYIEAGDHESSSLYIDYIVAEDPDMLMPPESEGPMSPAEIAILRLWIEEGANWPEDAQVVLSDPAAVEVVVVEPVPVPDSLASRVWAFQGYLHPATVHFPVALLTFGAAFVVLGYKWPQLAHPIPFACLLCGALSAIAASAMGWSFADQEGYGSWSKGLEASISRHRWTGVGVTITSVAFALIAIKAEMNENLRLRKVWQIGLLISAGMVGLVGHIGGELTYGEEFYHKAFEILSGTDSELPVIEIETVSTDGES</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQK4</accession>
    <name>A0A518IQK4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_13430</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022074769" evidence="1">
        <location>
            <begin position="23"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="122" mass="13417" checksum="BFB6B373F1103847" modified="2019-10-16" version="1" precursor="true">MTMMNWMTSFKGISLATIAAMAIGLSGCNKDQVTGDGAADPVAATNVDHSHGGWWCVEHGVPEEECALCDKSLVSKFKEDGDWCDEHDRPESQCFICSPARFDKFAMRYEAKTGQKPPQPEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQR3</accession>
    <name>A0A518IQR3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ribonuclease P protein component</fullName>
            <shortName evidence="5">RNase P protein</shortName>
            <shortName evidence="5">RNaseP protein</shortName>
            <ecNumber evidence="5">3.1.26.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Protein C5</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 6" type="primary">rnpA</name>
        <name evidence="6" type="ORF">Mal33_13980</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.</text>
            <dbReference type="EC" id="3.1.26.5"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5">Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the RnpA family.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.5" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004526">
        <property type="term" value="F:ribonuclease P activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001682">
        <property type="term" value="P:tRNA 5'-leader removal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00227">
        <property type="entry name" value="RNase_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000100">
        <property type="entry name" value="RNase_P"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33992">
        <property type="entry name" value="PTHR33992"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00825">
        <property type="entry name" value="Ribonuclease_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00188">
        <property type="entry name" value="rnpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="4 5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1 5" id="KW-0819">tRNA processing</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV55425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="128" mass="14680" checksum="D23ACC6766C90995" modified="2019-10-16" version="1">MIDQRFPKTLRLKTPEQFGRIIRKGRVATDRTLVLNAMSNGMDFSRIGITIPKKTGNAVVRNRWKRLIREAFRTQKEQLPQGFDFVVRPRRGAVADHAAIRKSLVSVAWRATGQRRGDDAKRKPDPKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IR17</accession>
    <name>A0A518IR17_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Planctomycete cytochrome C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Mal33_15120</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011429">
        <property type="entry name" value="Cyt_c_Planctomycete-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011444">
        <property type="entry name" value="DUF1549"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022655">
        <property type="entry name" value="DUF1553"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07635">
        <property type="entry name" value="PSCyt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07583">
        <property type="entry name" value="PSCyt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07587">
        <property type="entry name" value="PSD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022076526" evidence="2">
        <location>
            <begin position="24"/>
            <end position="1088"/>
        </location>
    </feature>
    <feature type="domain" description="PSCyt1" evidence="5">
        <location>
            <begin position="46"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="domain" description="PSCyt2" evidence="3">
        <location>
            <begin position="167"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="domain" description="PSD1" evidence="4">
        <location>
            <begin position="548"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="789"/>
            <end position="809"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV55535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1088" mass="121146" checksum="E8BB0E950C30E869" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IR79</accession>
    <name>A0A518IR79_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_15710</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010869">
        <property type="entry name" value="DUF1501"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019546">
        <property type="entry name" value="TAT_signal_bac_arc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07394">
        <property type="entry name" value="DUF1501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01409">
        <property type="entry name" value="TAT_signal_seq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="478" mass="52485" checksum="B40B9994CD3AE506" modified="2019-10-16" version="1">MDPRTEYAAFSTRRHFLQQSTAGVGAMALASLMAGDASGNDPLAAAKPHFPAKAKRVIYLHMTGSPPNLDMFDYKPELEQRDDQDCPDHFIEGKTFAFTSGKPKLLGSPRKWKQCGSNGTWMSDAIPNFHKTADDMCIVHSMYTDQFNHAPAELLVLTGSPRSGRPSLGSWTTYGLGSENENLPGFVVLISSGVQPNGGKNSFGSGFLPSVYQGVQCRSKGDPVLYSSDPAGMSRGMRRMSLDAIRDLNQIQAEQLGHPETMTRIAQYELAFRMQTAVPEVMDISQESQKTLDDYGAEVGGASLANNCLLARRLVESGVRFVQLFDWGWDFHGTGAATGIQKGLTDKCATMDKPIAALIKDLKQRGLFEDTLIVWGGEFGRTPFREGRTAKGKILGRDHYPDAFTMWLAGGGVKGGFDYGNSDELGFNVAEKPVHIHDLQATILHLLGFDHEQLTYRFQGRDFRLTDVHGHVVKDLLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRA5</accession>
    <name>A0A518IRA5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">2-dehydro-3-deoxyphosphooctonate aldolase</fullName>
            <ecNumber evidence="6">2.5.1.55</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">3-deoxy-D-manno-octulosonic acid 8-phosphate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">KDO-8-phosphate synthase</fullName>
            <shortName evidence="6">KDO 8-P synthase</shortName>
            <shortName evidence="6">KDOPS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Phospho-2-dehydro-3-deoxyoctonate aldolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 8" type="primary">kdsA</name>
        <name evidence="8" type="ORF">Mal33_16130</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>D-arabinose 5-phosphate + H2O + phosphoenolpyruvate = 3-deoxy-alpha-D-manno-2-octulosonate-8-phosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14053"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57693"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:85985"/>
            <dbReference type="EC" id="2.5.1.55"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Bacterial outer membrane biogenesis; lipopolysaccharide biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 6">Carbohydrate biosynthesis; 3-deoxy-D-manno-octulosonate biosynthesis; 3-deoxy-D-manno-octulosonate from D-ribulose 5-phosphate: step 2/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the KdsA family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.55" evidence="6"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00030"/>
    <dbReference type="UniPathway" id="UPA00357">
        <property type="reaction ID" value="UER00474"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008676">
        <property type="term" value="F:3-deoxy-8-phosphooctulonate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019294">
        <property type="term" value="P:keto-3-deoxy-D-manno-octulosonic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00056">
        <property type="entry name" value="KDO8P_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006218">
        <property type="entry name" value="DAHP1/KDSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006269">
        <property type="entry name" value="KDO8P_synthase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21057">
        <property type="entry name" value="PTHR21057"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00793">
        <property type="entry name" value="DAHP_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01362">
        <property type="entry name" value="KDO8P_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0448">Lipopolysaccharide biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DAHP_synth_1" evidence="7">
        <location>
            <begin position="13"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV55635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="278" mass="29400" checksum="DAA2BAD53962B013" modified="2019-10-16" version="1">MHQDGITPAKIGDYTCGPGNPLLLIAGPCVLETREAAIEIGLRLRDIGQEHGASIVFKASFDKANRTSLSSYRGPGLEAGLEILQAVGEATGLPVTTDIHLPEQAEAAGRVCDLLQIPAFLARQTDLLVAAAETGKAINVKKGQFMAPGDMRYVVEKLRESGSQNILLCERGTFFGYGRLVNDMRSIPEMQALGVPVVFDATHSVQQPGGLGGATGGNRAMVEPLARAAVAIGTDALFFETHPDPDKSPSDGPNMVPLDQFSGLVGRMLAIRRGLEAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRB2</accession>
    <name>A0A518IRB2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha-D-kanosaminyltransferase</fullName>
            <ecNumber evidence="3">2.4.1.301</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">kanE_1</name>
        <name evidence="3" type="ORF">Mal33_15990</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.4.1.301" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="26"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="415" mass="46151" checksum="24AC836684132615" modified="2019-10-16" version="1">MKSKPYRILMLLENESVPDDCRVLLEAEALIDAGYAVTIICPTGEVTKKVDRIGEIRVYRYPQAWEMSGVLGYLLEYGYSLVAAFVLSWFVLLRHGFDAVHVHTPPDLMGLVAIFFKLLGKRFVFDHHDLSPELYLAQKPGRSEGTVYRALRFFERLSCRKADRLIATNDTQRSIQIDRCGADPEDCYIVRNGPNALFLSDVQPLESIRTPGVLTIGYVGVIGVQDGVDFMVRALHEVKTKHGRDDFRGVIVGSGPAIADLKRLAAKLDLADKILFTGMIPFATVPSHIAAFDICLTPDPSNAYNDSCTTIKTMEYMALRKPTVCFRTRENQITAGDAAVYADNNDIPAYADAIVQLMDDPALRQSMGQTARQRIDNGLTWQHQAVRLIELYDNLFDVVRDPADCDAPAAVASVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRC4</accession>
    <name>A0A518IRC4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 10">Adenine phosphoribosyltransferase</fullName>
            <shortName evidence="10">APRT</shortName>
            <ecNumber evidence="5 10">2.4.2.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10 12" type="primary">apt</name>
        <name evidence="12" type="ORF">Mal33_16190</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>AMP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + adenine</text>
            <dbReference type="Rhea" id="RHEA:16609"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.4.2.7"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 10">Purine metabolism; AMP biosynthesis via salvage pathway; AMP from adenine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the purine/pyrimidine phosphoribosyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.7" evidence="5 10"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00588">
        <property type="reaction ID" value="UER00646"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003999">
        <property type="term" value="F:adenine phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006168">
        <property type="term" value="P:adenine salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044209">
        <property type="term" value="P:AMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006166">
        <property type="term" value="P:purine ribonucleoside salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00004">
        <property type="entry name" value="Aden_phosphoribosyltr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005764">
        <property type="entry name" value="Ade_phspho_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01090">
        <property type="entry name" value="apt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 10 12" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9 10" id="KW-0660">Purine salvage</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pribosyltran" evidence="11">
        <location>
            <begin position="39"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QDV55641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="176" mass="19192" checksum="5E367EF79FE84BFE" modified="2019-10-16" version="1">MSDASIDLRDYIRDVPDFPKPGILFRDITPLLKCPIAMSAVIDRLAAPYLDQKIDVVAAAEARGFIFAAPLAIRLNASFVPIRKPGKLPFTSHSLTYDLEYGTDTVQMHVDGVEPSQRVLVLDDLLATGGTVDACCQLLEKCGAEIVGCAFVINLKALGGEQRLSKYPLHSLLTYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRD5</accession>
    <name>A0A518IRD5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_15800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="174"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="295" mass="32328" checksum="3E528497DFD3883D" modified="2019-10-16" version="1">MNEATLVEAFRGIPRRDSVRIGIQVGKLRKVCMGDQALEAFFPEALDILLRLFHAPAGAFWFRPFNATTLFPISRVGFEQLSLSNSCLSACEQMVRGAWQSLAPQVRPIDRSFVSLIGPIRDGSTSIGALQLVADSGGDKDQQPKLVYARAMAGVLSLIQPAIHRRMQVGETSIREATDRLAQLADQLTGLQQSMRHAIDQTLGQLRGASFGSLEANQQFTRVIHELLETHGLRVVCPECGAAAILRCSKNPRTRDGVFVFDHSVAGRRTFHGGYTTLPVLQVVSKPPRRGKSLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRU5</accession>
    <name>A0A518IRU5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_17980</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="78" mass="8347" checksum="10552238B19DE842" modified="2019-10-16" version="1">MPRKNTSHLLELVGCLSLAATILVGSTGCQVSVAGQTLPSPYYLDDDVQYFPAGPEFKLPREAAALRAARAEEKLKGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRZ5</accession>
    <name>A0A518IRZ5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Pyrimidine-nucleoside phosphorylase</fullName>
            <ecNumber evidence="6">2.4.2.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">pdp</name>
        <name evidence="6" type="ORF">Mal33_18480</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.2" evidence="6"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004645">
        <property type="term" value="F:1,4-alpha-oligoglucan phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016154">
        <property type="term" value="F:pyrimidine-nucleoside phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006206">
        <property type="term" value="P:pyrimidine nucleobase metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006213">
        <property type="term" value="P:pyrimidine nucleoside metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1030.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000312">
        <property type="entry name" value="Glycosyl_Trfase_fam3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017459">
        <property type="entry name" value="Glycosyl_Trfase_fam3_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036320">
        <property type="entry name" value="Glycosyl_Trfase_fam3_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035902">
        <property type="entry name" value="Nuc_phospho_transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036566">
        <property type="entry name" value="PYNP-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013102">
        <property type="entry name" value="PYNP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018090">
        <property type="entry name" value="Pyrmidine_PPas_bac/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017872">
        <property type="entry name" value="Pyrmidine_PPase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000053">
        <property type="entry name" value="Thymidine/pyrmidine_PPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10515">
        <property type="entry name" value="PTHR10515"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02885">
        <property type="entry name" value="Glycos_trans_3N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00591">
        <property type="entry name" value="Glycos_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07831">
        <property type="entry name" value="PYNP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000478">
        <property type="entry name" value="TP_PyNP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00941">
        <property type="entry name" value="PYNP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47648">
        <property type="entry name" value="SSF47648"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52418">
        <property type="entry name" value="SSF52418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54680">
        <property type="entry name" value="SSF54680"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02644">
        <property type="entry name" value="Y_phosphoryl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00647">
        <property type="entry name" value="THYMID_PHOSPHORYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PYNP_C" evidence="5">
        <location>
            <begin position="339"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV55869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="431" mass="45737" checksum="271A3823C11C8A82" modified="2019-10-16" version="1">MIPAVLIAKKRDGHPLNDAEIAWFIEAFTRGEVSDPQMSAMAMAICLRGMTPLEISALTAAMLASGETLPRDSSSVPRVDKHSTGGLGDKVSLILAPLLACCEVQVPMISGRGLGLTGGTLDKLESIPGFRCDFDLDQSAQLLKAVGCHIVSASERLAPADRRLYSLRDVTGTVESVSLITASILSKKLAASLDALVMDVKVGSGAFMKSHSDALQLANALVETGTEMQLPVSALMTDMDQPLGRAVGNALEVNEVLDLLRGQGPGEVRELTLQLSAEALLAAKVCTSRDQALLRLQRVWDDGSAMERFEKMIAAQGGRISGQLPVAAKHPIVAQRAGFVSAVQCSTIGQCVVELGGGRRSAGDTIDPAVGLQVDVAIGERMESGQPLGFVFCSDDQAERWTKELQQAFVIADEVVAPRPLIIQRIESKKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IS27</accession>
    <name>A0A518IS27_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Legionella pneumophila major outer membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_18780</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011446">
        <property type="entry name" value="BBP7"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07585">
        <property type="entry name" value="BBP7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022184763" evidence="1">
        <location>
            <begin position="28"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="323" mass="35003" checksum="8DE52867E54B9780" modified="2019-10-16" version="1" precursor="true">MLKFHQKRFQVAAWFLLSMGLTSIAQGQFGCDASSGCDAVGCGATTRWSFGAKALFLERADDDVRIFSGANGNFDSDEFDLGFQAGYELNGRYNLNDSNALTVRWMSVDRWSDSHGDLVGPAGNATLNATAPVTFPGVTSIDGVHRSDLHSLELGISRRLTESVRLTTGFRYLEIDDRIGFRLDAAATPTTIDTAAQNRLYGGQIGLESELFRKGKWSLDGFGQVGLFGNAAKQSTLLDTGVVQIRDAGDRGKFSFLAELGLNARRSLTSQLDLVAGYQVMWVTSVAVASDELVHSNFIAPHGVDASDSVFYHGATVGLEYHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IS97</accession>
    <name>A0A518IS97_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_19550</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="462" mass="50034" checksum="CCFACBC47805FD9B" modified="2019-10-16" version="1">MVDRVAAVKSGIFRQPKLGGRMATLRRWCLVGLALLCCLPAGCRGGMQLTTARNQFYHGAFDDSQATLEKIKESDRKASVVSTLDLAMVHLAAGETDAAEQLLLEARGTLDENQAADPVAGTISYITDDTARQYRGWGYEQVMIRAMLALTSMMSDAVDAEAYALQAQSKQMELQQAAIDAGMLDADKHYQPLAFAPYVRGVLREMNYRDYDDASRAYRLVSEIQPSFAPAEIDIARAESGVHCQPGHGVVYIFALVGQGPQRVAQQAPVTSNVLLLADRVVSAVGKYSVPPTMAPIEIPAVAIPETAIDTVFVMADDQPLGLTQSITDVGQMAVQQYEAEKTDLLVRAVARRIVKKSAVAAGKDAFGIQDPMLQLVVDLAGSAWEATEKTDTRCWSLLPREIQVLRAELPVGTHNISLQAFGRGSPLQRDPTARTIEVEDGRNTYVLATAPSDRVIAAAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISL4</accession>
    <name>A0A518ISL4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_20390</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021991659" evidence="1">
        <location>
            <begin position="25"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="domain" description="GFO_IDH_MocA" evidence="2">
        <location>
            <begin position="30"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="394" mass="42218" checksum="77EDA7F659374662" modified="2019-10-16" version="1" precursor="true">MSLPRRSFLLSSASALAASRFAWAAAAKRRVAVIGHTGRGDFGHGLDTVWQQIPETKIVAVADANEAGLARQLSKLKIDHGFRDYQQMLRQVQPEFVAICSRHADQHHAMALAAIEAGARGLYIEKPICRTPAEADALLAACEKHDAKIAVAHRNRYHPALPQIDSLIANGRIGNLLELRGRGKGDHRGGAEDLWVLGSHVLNLVDHFTGPPKTCSAVMLQGGRRVTAADVRPGAEGLGPLAGDALHARYETTAGPIAYYDSVAKDGTAGTAFCLQLIGSRGTITIHMDGRPLAYLCEGSPFRPPAEPRRWLPISSGGVDVAEPNPKAVAEATHHIAAVKDLIESVDSGRRPLCDMQNAATTVEMICGVFESHRQESAAVALPLAKRDNPLTRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISQ0</accession>
    <name>A0A518ISQ0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_21010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011453">
        <property type="entry name" value="DUF1559"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07596">
        <property type="entry name" value="SBP_bac_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="94" mass="9975" checksum="3AF0F62A47644E22" modified="2019-10-16" version="1">MRRHAFTLVELLVVIAIIGILVGLLLPAVQAAREAARRMECSNNLKQFGLALHNYHDTYRKFPAGVFASNIPRGGGPTTSFGPSALSGLGIGVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IT23</accession>
    <name>A0A518IT23_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_22130</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="120" mass="13728" checksum="0F2575B2E875BB49" modified="2019-10-16" version="1">MAWSWSHTNEAYAAVEEQLNNKADAANNGDTEAAEWLQMVWSEWVASKREDNLIMADLNLRKYELCLVRAKRQGGLLGYEKLTKDIWEWTTELAACTNRGHEAYLCPHGCHLLPFSVEAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IT44</accession>
    <name>A0A518IT44_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_22150</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="68" mass="7539" checksum="0B515B8D6E9E312F" modified="2019-10-16" version="1">MPTIQTSVFDTLYTIVFTNTTLGRSVEEGLNVWVCENVAAFRQSLDVLKGKPHCRVISAGPSVVKREK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITJ2</accession>
    <name>A0A518ITJ2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_23990</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="106" mass="11991" checksum="8AFA14FE3C193206" modified="2019-10-16" version="1">MEVIDDWIDSEIKREMASFGHRGLSVEESARLVCRSPETVAKYHGGYCKPVWIPTPSEIAERAAEIRQRWTEEERLARIQAPVDVDYEPAESCGTRNDEGKVNANG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITM4</accession>
    <name>A0A518ITM4_9BACT</name>
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        <recommendedName>
            <fullName evidence="2">DDE_Tnp_1_assoc domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_24180</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032806">
        <property type="entry name" value="YbfD_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13808">
        <property type="entry name" value="DDE_Tnp_1_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="domain" description="DDE_Tnp_1_assoc" evidence="2">
        <location>
            <begin position="23"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="177" mass="18971" checksum="7D123D9F38D11469" modified="2019-10-16" version="1">MELYSTYGETTVKVPAAGSLLAILAAIPDYRGRKGRRHSLAAMLAAIICGLLTGAKGCTAIAQWLHDQEPEFWHSIGFARKPPTSNCFRDVLLGLPPGTLENAVRAWVTEYLAAVPGELRPVALDGKTLCGTLQPHGQSIHLLAMFDTATGGVIAQARMPATPMNIRWRCGCCEAIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITN6</accession>
    <name>A0A518ITN6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Bifunctional hemolysin/adenylate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">cya_1</name>
        <name evidence="2" type="ORF">Mal33_24430</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.150.10.10">
        <property type="match status" value="19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018511">
        <property type="entry name" value="Hemolysin-typ_Ca-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001343">
        <property type="entry name" value="Hemolysn_Ca-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011049">
        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00353">
        <property type="entry name" value="HemolysinCabind"/>
        <property type="match status" value="29"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51120">
        <property type="entry name" value="SSF51120"/>
        <property type="match status" value="14"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00330">
        <property type="entry name" value="HEMOLYSIN_CALCIUM"/>
        <property type="match status" value="37"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="560"/>
            <end position="799"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="818"/>
            <end position="922"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1094"/>
            <end position="1208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1233"/>
            <end position="1255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1439"/>
            <end position="1608"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1784"/>
            <end position="1955"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2155"/>
            <end position="2206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2220"/>
            <end position="2294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2474"/>
            <end position="2645"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2808"/>
            <end position="2869"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="565"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="602"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="782"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="901"/>
            <end position="922"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1940"/>
            <end position="1955"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="2626"/>
            <end position="2645"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="2836"/>
            <end position="2855"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="3010" mass="303431" checksum="6E01862CAAFEF726" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IU71</accession>
    <name>A0A518IU71_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_26210</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="448"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="457"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="485" mass="48901" checksum="40275CE59E829F87" modified="2019-10-16" version="1">MRIGLTHLMLSIAGTVLVTGCAPVRHNLPPAERMMQPGPGVGGPGPGVLAPPAMQMGGGGPMMGGPGMGPGPMMGGGPMMGPGQMGPGQMPPGASEPGSQVAQMPSPIAQAAFNGMYGSGMSNVCNASSGCGCSSCSGGMDDGGGEIVQAAFQMNPTVQVTFARPDSMHVQYDVSGGGSFDSEPLVVPARQNFPAGGLYRLKLTNIVGREGVELYPSLEIAPGNPRTGAYLAHNSIPIQITEEDLDQVLTGNFVTKVIYLPDPDFQGPALAGIDTLVSTRLDPGVDPIIEADRRGSILAILRLGDKDIEMAGQMGAGAMLGGMPNGAGGYMMGMAGAGGYAMGNCANGSCGPMGIPGGAPMPPGLPGMISGVTAPQYGMPITGTPIGLPGPPHIPLGGPASLKSHTMTNRTHSVMPSPVKDVKIGVKMQPGYSYPHPVSRINITEQNIHPGTAYGRPGYTQGSQAVSSPNAPGTVPGGGAYCPPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUA2</accession>
    <name>A0A518IUA2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FG-GAP repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_26690</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.130">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013517">
        <property type="entry name" value="FG-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028994">
        <property type="entry name" value="Integrin_alpha_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011519">
        <property type="entry name" value="UnbV_ASPIC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13517">
        <property type="entry name" value="FG-GAP_3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07593">
        <property type="entry name" value="UnbV_ASPIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69318">
        <property type="entry name" value="SSF69318"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="UnbV_ASPIC" evidence="2">
        <location>
            <begin position="484"/>
            <end position="543"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="560" mass="60103" checksum="3DE5F060B69AC916" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUI8</accession>
    <name>A0A518IUI8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulatory protein TdiR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">tdiR_1</name>
        <name evidence="5" type="ORF">Mal33_27460</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="1"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="136"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV56748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="212" mass="23672" checksum="AA4C9914A49D8A6B" modified="2019-10-16" version="1">MPDGLTFYLFSNFDHRVRTVVRTAADRFADAAVRELSHQALLSPQPPTEAGCILIDLDQTAGLDAVREFIVANGQQSKIILISERADLKLARQAFPLGVFDCLAKPVDPEQLLDSIARATEAIRCDRKTWRVSRSDAAAVEALTPRELEYFSKLLEGWSIKTLSTHFQVSIQTAAKHRSRVLAKLKAENEVELVHRFGTTRLTFPRDPGDSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IV03</accession>
    <name>A0A518IV03_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phosphorylated carbohydrates phosphatase</fullName>
            <ecNumber evidence="1">3.1.3.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_29060</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.3.-" evidence="1"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="203" mass="22513" checksum="F902133D18431EBA" modified="2019-10-16" version="1">MFDTEPLYYQVGTELLGRRGFEFNMQIQQKMMGRPAPEAIGVLIAEFQLTDLPADLMQESDDLYAALLAEGLVALPGLFELLDHLETQSIPFAVATSSKRRFAQQMLSSFDLIPRLQFLLTGDDVSQGKPHPEMYLAAADRFQIQPENMLVLEDSENGCISAARSGACAVAVPGEHTAGHRYDQAFLSIDSLADRRLFELLQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IV09</accession>
    <name>A0A518IV09_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glycoamylase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_29230</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019282">
        <property type="entry name" value="Glycoamylase-like_cons_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016883">
        <property type="entry name" value="UCP028431"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10091">
        <property type="entry name" value="Glycoamylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028431">
        <property type="entry name" value="UCP028431"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021884015" description="Glycoamylase-like domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoamylase-like" evidence="2">
        <location>
            <begin position="196"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="435" mass="48452" checksum="D4A076D45CFA2B3A" modified="2019-10-16" version="1" precursor="true">MKRRSFLFVSGLSLPPLVQAANADVVARDDGLFLRDMQQRCYRYFLEASHPATGLVSDRSAADGSRASEHSSIAACGFGLAAHAIAADQEWLPRGEIAERVEVLLRTLVERADHERGFLYHFLNRADARRTWNSEASTIDTALVIAGAMTAAGCFSEERSIVALADALYRRVEWTWMLGSDDCLHMGWTPEDGTIPHRWDHFSELLILVLLAIGAPENPIPPRCWQAWNRRPILTFGDTSFLSYPPLFVHQYPAAFFDFRRFRSPSGRSYFDNAVTAHLAQIQFMTDLGNKYPDQLGHYGPRLWGLTSSDSDAGYRDWGGPYQDGRCEPDRGIDGTLVPSAAAGGLPFVPRQAMETLRYQESQFGDAIYGRYGFVNAHNPASGWIDSDVIGIDTGISLLMAENLISGSVWDWFGRHPAAIRGLRLAGFSRDEQID</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IV16</accession>
    <name>A0A518IV16_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cyclic di-GMP phosphodiesterase response regulator RpfG</fullName>
            <ecNumber evidence="2">3.1.4.52</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rpfG_4</name>
        <name evidence="2" type="ORF">Mal33_29350</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.4.52" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071111">
        <property type="term" value="F:cyclic-guanylate-specific phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037522">
        <property type="entry name" value="HD_GYP_dom"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51832">
        <property type="entry name" value="HD_GYP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD-GYP" evidence="1">
        <location>
            <begin position="127"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="402" mass="44257" checksum="07516D99BFA8B311" modified="2019-10-16" version="1">MGTLAESGHQLNVGELLQEDILSSSGDVLYRAGEPITADIAATIQRHGLRRVLQDSEQAFDSSATSGIHRQQRLKMANEPYSQERAAVLRRLIDESTFKIREMTATLHGRGRVDWQDLAEIPSRFAKQSEQDIDQTLSSTLHQSEYHELSSHCLTLSTLGMMIAQEIPGCDVDEILDVGIAGSLHEMGLGELELGPEARSRRSELSASDFATYSRHPIVAYQLCGSISGLSDRARMGIQHVHEQLDGTGFPHGVGGSQVNRIARILNVADAYLTLQNSLDGRPAVKPYDALVCLLHQVRAGRCDAEAVRGLLNLVSLFPVGSFVRLDDARIARVIRSNSPYYTKPTVVTLDTDELINLRESDLQIVAIEANPSSQEIRLQQDELQRPIWIPSVHQPQGTSAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IV99</accession>
    <name>A0A518IV99_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_30130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="113" mass="12254" checksum="31AF97CDD0A08F6D" modified="2019-10-16" version="1">MGTTNSKMSLPQFGVGIVAVAIVAAGLWWWMRPPAPLSENGYDLTIALYRVCNQRSDEGLQRIEQLLAESRSTGEASDPSHGIVAAIVAQAKTGDWESAARASRRALEDQVKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVE2</accession>
    <name>A0A518IVE2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">MotA_ExbB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Mal33_30530</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the exbB/tolQ family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002898">
        <property type="entry name" value="MotA_ExbB_proton_chnl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01618">
        <property type="entry name" value="MotA_ExbB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="15"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="82"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="114"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="MotA_ExbB" evidence="8">
        <location>
            <begin position="63"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV57052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="160" mass="17787" checksum="6A381B227A3F4455" modified="2019-10-16" version="1">MTSIENLLFDMAQLFWWPVLLLVLFTFAYALFKLGGFLIEAFLRLRLPQRHWVVPTNATGSLESMELLVLRELEGLRLCSRIAPMLGLVATMIPLGPALAAVSSGQSQITANSMGGAFAAVIIALVAASITFAIYTIRRRWLMQELTHWMESQTSEPEST</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVF9</accession>
    <name>A0A518IVF9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_30770</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="313" mass="34717" checksum="56532494D6C134CE" modified="2019-10-16" version="1">MSQQPSGLSQFHFAPAEVIHLMHAAMLAELASSLALHGPSLLADGASIPPAALQDYWVVSRNRSTRWHQTLAMHRQLDRSGDRIGLQAWWEQHLPTLEEILVSEILTRVYAALGHGLDAKHAEPEIYPVVHSVHISHLEARNRVLGLMVAQRGGSSQTTARLNQLRKSVERWTDVLVAQIAAVNPDAARYGTVLERTLEFADEAADQAGAVRQTHRRLLTATLRSSLLRQMHATAANPDENGKISDAVLVCIRPDMFDSLGTLQSLWLHRLKHSAEQTDSVLTQLLAPNLATADLLPDFEAVRAPEFARRLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVQ7</accession>
    <name>A0A518IVQ7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_31660</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="99" mass="11602" checksum="42AF78C4EFB2C9BA" modified="2019-10-16" version="1">MKSDKSCGVRVPQVKEVPRWCRRCREVVPHVCYENISRRSVVLLSAATLGAAYPFLNRYYRKSQNRCLYCSAENNGRYFNRQRQRQRKRTSGAATSLRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVS1</accession>
    <name>A0A518IVS1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">pknH_1</name>
        <name evidence="10" type="ORF">Mal33_31840</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="385"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="10"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="285"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="598"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV57183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="621" mass="68868" checksum="2516AD887AB91829" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVV1</accession>
    <name>A0A518IVV1_9BACT</name>
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        <recommendedName>
            <fullName evidence="2">AAA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_32170</name>
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    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetia</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
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    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
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        <property type="entry name" value="AAA_22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="2">
        <location>
            <begin position="287"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1360"/>
            <end position="1380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1914" mass="217171" checksum="1F7299BEA2B4DF28" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWF5</accession>
    <name>A0A518IWF5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_34380</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="DUF1552"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07586">
        <property type="entry name" value="HXXSHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="446" mass="48711" checksum="70A5C46C8CA99A52" modified="2019-10-16" version="1">MIHNQQINRRIMLRGLGVAMGLPLLEAMTPMARSVMASPSSKTMPTRMACVFFPNGVIVPKWQPAKGPELVLGESLQALQPLKHKLTMVSGLALDNGRAKKDGAGDHARAGSTFLTAARPVKTSTDIKVGVSVDQLAAQQIGQETRLASIELGVLGSRNAGSCDSGYSCAYSSNVSWRSENQPAAKETVPRLAFERLFGTGDNAATRERDFYRKSILDVVAQDARKLDKKLGTTDRRKIDEYFTGVRELERRIEMTEAEDRKGVPDLELPHGRPKQFVEHADLMSDLMVVAFQTDATRVATFMLDNAGGNRSYPDIGVNDGHHQISHHSNHEGKVANLQKIDAHLAERLAYFLQKLDSVQEAGGTLLDHSMVLYGSGLSDGNRHRHEDLPIVIAGGARGRIKTNRHIELGEETPMANLFMSMLDIVGAPVESIGDSTGRLDQLTTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWJ6</accession>
    <name>A0A518IWJ6_9BACT</name>
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        <submittedName>
            <fullName evidence="5">Response regulator ArlR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">arlR</name>
        <name evidence="5" type="ORF">Mal33_34780</name>
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    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
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        <property type="entry name" value="HDOD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08668">
        <property type="entry name" value="HDOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51833">
        <property type="entry name" value="HDOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="10"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="HDOD" evidence="4">
        <location>
            <begin position="186"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="135"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="448"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="139"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="448"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV57468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="578" mass="63827" checksum="4A1ACA8B1C219908" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWJ9</accession>
    <name>A0A518IWJ9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Dephospho-CoA kinase</fullName>
            <ecNumber evidence="1">2.7.1.24</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Dephosphocoenzyme A kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1 3" type="primary">coaE</name>
        <name evidence="3" type="ORF">Mal33_34450</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>3'-dephospho-CoA + ATP = ADP + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18245"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57328"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.24"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 5/5.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the CoaE family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.24" evidence="1"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00241">
        <property type="reaction ID" value="UER00356"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004140">
        <property type="term" value="F:dephospho-CoA kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00376">
        <property type="entry name" value="Dephospho_CoA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001977">
        <property type="entry name" value="Depp_CoAkinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01121">
        <property type="entry name" value="CoaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00152">
        <property type="entry name" value="TIGR00152"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51219">
        <property type="entry name" value="DPCK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0173">Coenzyme A biosynthesis</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="37"/>
            <end position="42"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="225" mass="25469" checksum="46CF25ECAA833D75" modified="2019-10-16" version="1">MPTAARRSDKRERAAHGTTSDQTSYNMIVIGIIGPPAGGKSTVARALAEQGAAWINADRLAHAALRMGRVKNKLREHFGDSIFNTAGAVQRPALAAKVFGDDPTSRRQLEYIESVLHPVVGQLAARKLQRLAAQQQSVVVIDAPLLIEANWHFQCDEIWYVDSPWEQRIQWIAKRSWTPEQLRQREARQLSLAEKRRYATRILDNSQGPPHTRRQILALWRQLTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWN8</accession>
    <name>A0A518IWN8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">UPF0316 protein Mal33_35200</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Mal33_35200</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 7">Cell membrane</location>
            <topology evidence="2 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the UPF0316 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01515">
        <property type="entry name" value="UPF0316"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019264">
        <property type="entry name" value="DUF2179"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044035">
        <property type="entry name" value="DUF5698"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022930">
        <property type="entry name" value="UPF0316"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40060">
        <property type="entry name" value="PTHR40060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10035">
        <property type="entry name" value="DUF2179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18955">
        <property type="entry name" value="DUF5698"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="40"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="69"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="DUF5698" evidence="9">
        <location>
            <begin position="28"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2179" evidence="8">
        <location>
            <begin position="119"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF10035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF18955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV57510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="179" mass="19355" checksum="AF559B0EAF6E8434" modified="2019-10-16" version="1">MIESFSVPLASAALIFVLRLVDVSLGALRISMLFRGRRGLAGMFGFFEALTWLIAASLVLGNLDSPIKFIAFASGYAAGTMLGSTVESWLAIGDALVRIVTPSGTPELSQLMRDAGYYVTTVDARGRDGDVQVNLSVIPRKMVPNLMSMIHRINPQAFITYEETTPLRLATTAALSVRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWT7</accession>
    <name>A0A518IWT7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Endonuclease MutS2</fullName>
            <ecNumber evidence="6">3.1.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">mutS2</name>
        <name evidence="6" type="ORF">Mal33_35690</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
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        <location>
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            <end position="26"/>
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        <location>
            <begin position="1"/>
            <end position="18"/>
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    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="QDV57559.1"/>
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    <sequence length="650" mass="71356" checksum="A14B9FE9A67C20ED" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWV1</accession>
    <name>A0A518IWV1_9BACT</name>
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    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </dbReference>
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            <dbReference type="EMBL" id="QDV57546.1"/>
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        <source>
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    </evidence>
    <sequence length="570" mass="63250" checksum="55F67D8F07E95FA3" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWV8</accession>
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        <submittedName>
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    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
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                <person name="Kohn T."/>
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                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="449" mass="49739" checksum="F8FDCBA433CCD79A" modified="2019-10-16" version="1">MRSFIAWTICWLVVLVSTGGPLAAADWLSFLGPTANGKSTETGILTDWSDGKLKLLWTLDLDTSYGIGAVDQGRYFQFDRVGDVERLICLDAASGREIWHADQPVAYRDMYGYNNGPRSSPVIAGNRVFTYGVAGRLSCFDKTDGKLLWTHSLNEEFGVIQNFFGVSCCPVIYKDMVIVMVGGSPAADQRLPLGALDRVIGNNSGIVAFRQSDGKLAYQLSDELASYSTPVIAKIDGQDVGLAFMRGGLLAFDPNKGEELWHFPWRSPRLESVNAALPIVRGDQVLISECYDVGSALLKVTPRDYELLWKDPRSRRAQAMRAHWATPIQHGDYLFGCSGRNEPDSDLRCIRWSDGEVMWTKPNRIRTSLLWIDGHFVVLDERGHMELIKDSSDSYQPVTEIDLSEALGDSEAPFLRSPCWAAPVVANGRLYVRGANRVACFQLIPSAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWZ1</accession>
    <name>A0A518IWZ1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Asparagine synthase</fullName>
        </submittedName>
    </protein>
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    <organism evidence="2 3">
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        <lineage>
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            <taxon>Pirellulaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004066">
        <property type="term" value="F:asparagine synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006529">
        <property type="term" value="P:asparagine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001962">
        <property type="entry name" value="Asn_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00733">
        <property type="entry name" value="Asn_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Asparagine synthetase" evidence="1">
        <location>
            <begin position="171"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="442" mass="49715" checksum="4D1F0E1B2CD85425" modified="2019-10-16" version="1">MHNHQYVERFVSLLDPDANILLNATVDEAVELLGSGDAEALKNIEGQFALVHRNGHIVRMARSIGRPMRYFLAKQVDGPCLVVAERMDEIRDWLIAEGLDGQFHPSYTRMVPAHHIVEIALLGCPDPNPQYTRFFTPQRNRLPANLDEIGGRYIGALQASIAQWIDQIDPTEPIGVLFSGGIDSGAVFCTTYDCLLKRGDSPARLKAFTLSIDGQGRDADQAHRFLSDLDLGMFLEVIDCPVGEVDYREAIRVIEDYKPLDVQAATMGLALCRGIRRRYPDWKYLLDGDGGDENLKDYPIEENRELTIRSVLNNLMLYQEGWGVDAIKHSLTYSGGQSRGHVRSFAPVRQTGFQGFSPFAVPRVIEVAEGIPFIELTDWQHDKLYALKGEIVRRGVEQVTGLTMPTFEKCRFQHGASTEEVFANLFPADEQSYRNAFRQVLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWZ3</accession>
    <name>A0A518IWZ3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Large cysteine-rich periplasmic protein OmcB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">omcB_3</name>
        <name evidence="4" type="ORF">Mal33_36080</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001434">
        <property type="entry name" value="DUF11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01345">
        <property type="entry name" value="DUF11"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01451">
        <property type="entry name" value="B_ant_repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022055129" evidence="2">
        <location>
            <begin position="24"/>
            <end position="858"/>
        </location>
    </feature>
    <feature type="domain" description="DUF11" evidence="3">
        <location>
            <begin position="405"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="domain" description="DUF11" evidence="3">
        <location>
            <begin position="728"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="175"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="299"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="206"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="300"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="340"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV57596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="858" mass="91848" checksum="644923404A139981" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IX37</accession>
    <name>A0A518IX37_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Rhodanese domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_36560</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodanese" evidence="2">
        <location>
            <begin position="97"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="208" mass="22574" checksum="D33B8B1AD6CE07EC" modified="2019-10-16" version="1">MVGRESVANDLTVHAIVTFNSVTPTRRKILMYRNFMPLLIASLMLLAFVAQPAPAQLGSLFGFGPKVPTISTADLNKQLASQRDAEAKAQAAGTTAPVPDFVVVDVRSDAEVNVSVIPGAITKAEFEKNQQQYQGRTVIAYCTVGGRSGKYAAQLAKDGVDVKNYKGSILKWVDAKLPLVTLEGQPTNRVHTYSDRYSVPAEYEQVTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IX50</accession>
    <name>A0A518IX50_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Amidohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_36710</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04909">
        <property type="entry name" value="Amidohydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="1">
        <location>
            <begin position="3"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="282" mass="31798" checksum="81DDC4BCBD37A933" modified="2019-10-16" version="1">MKIDSHHHLWNYDPAQYGWISEQMSVLRRDFAPADLQTELTGAGIDAAVAVQAQQTVAETQWLIEQAEQNRSIVGVVGWVPLADDGVDSELDRLHQHEVLKGIRHVVQDEPQDDFILGDAFNRGVAKLQGFGLVYDILIYGKHLGPTIEFVDRHPSQPFVLDHIAKPTIRGEQFDKDWATQLRELGRRRNVVCKFSGVATEVRDEGAAIETIRPYWEAALEAFGPNRLMFGSDWPVCLLKLSYRQWVEMVAELASGLTAAEQKQFWGLTAATTYGLSFPSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IX52</accession>
    <name>A0A518IX52_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Photosystem I assembly protein Ycf3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_36770</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022178462" evidence="2">
        <location>
            <begin position="22"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="114"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="148"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="182"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="352" mass="39396" checksum="6432F85ADB7C5EAE" modified="2019-10-16" version="1" precursor="true">MHRQLLLIATCILGWAGTAAAQQPTTAASLKTAYSISKNATSESEYTQIIDQIQQSDLAAADEEVRSYGNQLLAWALNRRGELRWDQIQAPDDEFATAAIEDFRNALRLDPNRWRAKQNMAFVYATRGQMKEAEALFDDVIQTKPDHANAFFNRGELRYEMGKLPAAISDYDRAIALQPGEADFYTGRGHARFQHGDIGPAIDDYRRAFQLDKGNATRAIDLADALQNAGQWRSAAENYRNALRLDSQNLRTLLNLAWLLATCPDGSLRDGQQALEITQELRDIPANEEFRYIDTYAAALAETGQFEKATRVAQTGLNLVPASERSGFEARVANYKSNQRYRQSPIRQVGGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXA6</accession>
    <name>A0A518IXA6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Flotillin-like protein FloA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">floA</name>
        <name evidence="6" type="ORF">Mal33_37320</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts FMMs are highly dynamic and increase in number as cells age. Flotillins are thought to be important factors in membrane fluidity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homooligomerizes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Membrane raft</location>
            <topology evidence="5">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the flotillin-like FloA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045121">
        <property type="term" value="C:membrane raft"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01562">
        <property type="entry name" value="FloA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022853">
        <property type="entry name" value="FloA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12127">
        <property type="entry name" value="YdfA_immunity"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV57719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="364" mass="39172" checksum="F6C60A80BD1BF303" modified="2019-10-16" version="1">MAALNSLMLLAQGKDANVLWLAVIVVMVIGMMVFAMVFFSYFGLWIQSLLTGAKVTLGDLLGMTFRNVNARTIVRGKIMSTQAGIEDPELTSKALEAHYLAGGNVPQVIRALIAAKKAKTISLTFREATAIDLAGRDVLESVQTSVYPKVIDCPPRGSVKPSLDAVAKDGIQLKVKARVTVRANLQQLIGGATEETIIARVGEGIVSAIGSADGHKNVLENPDLISKWVLSKRLDSQTAFEIVSIDIADIDVGVNVGARLQADQAEADTRVARARAEGRRAMAVAEEQEKLAEIENSQAMLVAAQAEVPLAMAEAFRSGKLGILDYYKLQNINADTDMRKAISRSTRDASELAIQKQQRAQAQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXG6</accession>
    <name>A0A518IXG6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">4-carboxy-2-hydroxymuconate-6-semialdehyde dehydrogenase</fullName>
            <ecNumber evidence="7">1.1.1.312</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ligC_2</name>
        <name evidence="7" type="ORF">Mal33_37950</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.312" evidence="7"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050606">
        <property type="term" value="F:4-carboxy-2-hydroxymuconate semialdehyde hemiacetal dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016798">
        <property type="term" value="F:hydrolase activity, acting on glycosyl bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008152">
        <property type="term" value="P:metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019546">
        <property type="entry name" value="TAT_signal_bac_arc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01409">
        <property type="entry name" value="TAT_signal_seq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0520">NAD</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GFO_IDH_MocA" evidence="6">
        <location>
            <begin position="37"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV57781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="502" mass="55070" checksum="5CCE3B6A300C7E93" modified="2019-10-16" version="1">MSKLSRRQFVHTSAAAGAGLAVSGRLAHAVQSNEKIGVALIGAGGRGGSHLNAWLGDKRTDLLTIVDVDEKAAASRADAAEKAQGFRPKIVTDMREVFDDKSIDVISTATPNHWHALCGIWAMQAGKDAYIEKPVSHNIHEGTALIAAARKYDRICQVGTQCRSATAQQEMVDFIQAGGIGEVNFARGLCYKRRKSIGALGDYAVPDNVDFNLWSGPAAYTDPKVTRPRFHYDWHWQRLYGNGDSGNQGPHQTDVARWGLGIDTHPISVISYGGRLGYQAERKDDNYVDAGDTPNTQVSIYDYGDKCMVFETRGLGVDNSDDAELNKLFKSTKGNKIGVVFYGSNGYCVQVSYGHSIAYDADMNVIKEFKGAKDHFANFLDAVESRNYKDLTADVREGHLSASLSHLGNISLAIGEQKKMSVKEATEHLSKIKSLDDNDATLQRTIKHLEKNGVDLEKYPIAMGPLLKFDPEKEIFPENEVATAMCTREYRAPFVCPTADKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXT3</accession>
    <name>A0A518IXT3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cytochrome c-type protein NrfH</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">nrfH</name>
        <name evidence="6" type="ORF">Mal33_39010</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022900">
        <property type="term" value="P:electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3820.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036280">
        <property type="entry name" value="Multihaem_cyt_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005126">
        <property type="entry name" value="NapC/NirT_cyt_c_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038266">
        <property type="entry name" value="NapC/NirT_cytc_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017571">
        <property type="entry name" value="NrfH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03264">
        <property type="entry name" value="Cytochrom_NNT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48695">
        <property type="entry name" value="SSF48695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03153">
        <property type="entry name" value="cytochr_NrfH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="30"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrom_NNT" evidence="5">
        <location>
            <begin position="30"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV57886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="174" mass="19099" checksum="3A32F7BA8D62BE56" modified="2019-10-16" version="1">MSADSSQTDAPLDEGQPPDEAKRPMRFGKVAMTFFVCLGLLAGVGTFTFGYGKGASYLSNNPETCINCHVMQDHMDSWQQSSHHHVAVCNDCHLPHDFVGKWVTKADNGFFHSLAFTMGGYKDPIQIKPRNQRVTQSTCISCHKDFVHPLLPATAGHDMLSCVHCHADVGHAGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXV8</accession>
    <name>A0A518IXV8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Inosose dehydratase</fullName>
            <ecNumber evidence="2">4.2.1.44</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">iolE_2</name>
        <name evidence="2" type="ORF">Mal33_39340</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="4.2.1.44" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050114">
        <property type="term" value="F:myo-inosose-2 dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013022">
        <property type="entry name" value="Xyl_isomerase-like_TIM-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01261">
        <property type="entry name" value="AP_endonuc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="SSF51658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AP_endonuc_2" evidence="1">
        <location>
            <begin position="23"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="334" mass="37389" checksum="19AE6966BC7FA506" modified="2019-10-16" version="1">MARPVTLFTGQWADLGIQDLARMCSEFGYDGIELACWGDHFEVDRANAEDDYCAKKRELLDSHGLQCLAISAHLVGQAVCDIIDQRHQLILPSYVWGDGDPAGVNERAIEELKQTARAAQKMGVSVVNGFTGSSIWHLLYSFPPVSAQMIDDGFKLFADRFNPILDVFAECGVKFALEVHPTEIAFDIHTAQRALEALDHRPEFGFNFDPSHLIWQGMDPEKFIRAFPDRIYHVHVKDAIVKLDGTSGILSSHINFGDHRRGWDFRSPGRGGVNFEEIIRALNDIDYQGPLSIEWEDSGMERCFGATEACKFTKELDFAPSGRAFDQAFEDGNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXW4</accession>
    <name>A0A518IXW4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Helix-turn-helix domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_39370</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041657">
        <property type="entry name" value="HTH_17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010093">
        <property type="entry name" value="SinI_DNA-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12728">
        <property type="entry name" value="HTH_17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01764">
        <property type="entry name" value="excise"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_17" evidence="1">
        <location>
            <begin position="78"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="148" mass="16393" checksum="1AB060167503EACA" modified="2019-10-16" version="1">MSVLDETFVPSETDIANAKEFSRAVARDIDPTSVITIQSTGDGRSIEVPKNVFDVLVKTLAIMAEGKAFSLIPVDKELTTQQAADILNVSRPFLSKVLDLGEIPHRKVGRNRRVKFRDLIEYKKKQEQSSKAALQSLADEAQELGMGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXY6</accession>
    <name>A0A518IXY6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Enoyl-[acyl-carrier-protein] reductase [NADH]</fullName>
            <ecNumber evidence="6">1.3.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">fabI_2</name>
        <name evidence="9" type="ORF">Mal33_39650</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a 2,3-saturated acyl-[ACP] + NAD(+) = a (2E)-enoyl-[ACP] + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:10240"/>
            <dbReference type="Rhea" id="RHEA-COMP:9925"/>
            <dbReference type="Rhea" id="RHEA-COMP:9926"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:78784"/>
            <dbReference type="ChEBI" id="CHEBI:78785"/>
            <dbReference type="EC" id="1.3.1.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.9" evidence="6"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00128">
        <property type="reaction ID" value="UER00191"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004318">
        <property type="term" value="F:enoyl-[acyl-carrier-protein] reductase (NADH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016631">
        <property type="term" value="F:enoyl-[acyl-carrier-protein] reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014358">
        <property type="entry name" value="Enoyl-ACP_Rdtase_NADH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43159">
        <property type="entry name" value="PTHR43159"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000094">
        <property type="entry name" value="Enoyl-ACP_rdct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="5 6" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="6" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="5 6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="4 6 8" id="KW-0520">NAD</keyword>
    <keyword evidence="3 6 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="8">
        <location>
            <position position="16"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="64"/>
            <end position="65"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="95"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="162"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR000094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000094-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000094-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV57949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="267" mass="28677" checksum="AD68E21FC838E0A7" modified="2019-10-16" version="1">MTDFLKLSGRNILVMGVANKKSVAYHVAKTLEEVGANVIYSVRSEQRRASLAKLLPGREIVICDVSQQVEIDALAAYISDNGWTIDGLLHSIAFADYSDGIKPFHETTRAQFLQAVDISCFSLVAICNALRGCFSDDASVVTIGISTTRMASESYGYMAPIKAALASSLAFLTKSFSKFSQVRFNSVAAGLLKTSASAGIPGYVDSYLFAESVIPRGKAVSTSEVADTAAFLLSPRSSGICAQQLIVDAGMEINYFDQDVVRRATDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYB1</accession>
    <name>A0A518IYB1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative peptidyl-prolyl cis-trans isomerase</fullName>
            <ecNumber evidence="2">5.2.1.8</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ppiB_3</name>
        <name evidence="2" type="ORF">Mal33_40890</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="5.2.1.8" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000413">
        <property type="term" value="P:protein peptidyl-prolyl isomerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044016">
        <property type="entry name" value="Big_13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015919">
        <property type="entry name" value="Cadherin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044666">
        <property type="entry name" value="Cyclophilin_A-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002105">
        <property type="entry name" value="Dockerin_1_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045474">
        <property type="entry name" value="GEVED"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625">
        <property type="entry name" value="PTHR45625"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19077">
        <property type="entry name" value="Big_13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00404">
        <property type="entry name" value="Dockerin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20009">
        <property type="entry name" value="GEVED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49313">
        <property type="entry name" value="SSF49313"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="SSF50891"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="1">
        <location>
            <begin position="223"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1273" mass="134467" checksum="02BF4533124B7AB9" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYB3</accession>
    <name>A0A518IYB3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 7">4-alpha-glucanotransferase</fullName>
            <ecNumber evidence="3 7">2.4.1.25</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5 7">Amylomaltase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6 7">Disproportionating enzyme</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">malQ</name>
        <name evidence="8" type="ORF">Mal33_40940</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>Transfers a segment of a (1-&gt;4)-alpha-D-glucan to a new position in an acceptor, which may be glucose or a (1-&gt;4)-alpha-D-glucan.</text>
            <dbReference type="EC" id="2.4.1.25"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the disproportionating enzyme family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.25" evidence="3 7"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004134">
        <property type="term" value="F:4-alpha-glucanotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102500">
        <property type="term" value="F:beta-maltose 4-alpha-glucanotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003385">
        <property type="entry name" value="Glyco_hydro_77"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32438">
        <property type="entry name" value="PTHR32438"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02446">
        <property type="entry name" value="Glyco_hydro_77"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00217">
        <property type="entry name" value="malQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7 8" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00031423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV58077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="498" mass="56730" checksum="4804E49DB6CE884A" modified="2019-10-16" version="1">MQLPRSSGILLHITSLDNEFGIGDLGEGAYRFIDFLQRSGQSLWQLLPLGPSAAENSPYSCYSAFAANPLLISPTDLQRRGLLTAEEVQSLHAAKGPIDYGAVNNRRMELLKTSFERFQSPVGDSLRDGFASFCAMNQAWLVDFARYKALTDHFGIGDWSQWPDRDLVLRREGALEHWDRELAQPIEFAKYLQFLFMLQWQALKSYAGEHGVRIFGDMPIFVAYDSADVWAHQDLFHLDEAGKRYVVAGVPPDYFSATGQLWGNPLYRWDAMKDHGYEWWIDRLQSAFCYFDLLRIDHFRAFEAYWEVPADAETAVDGVWMPGPMDGPFRAARAALGPLAIIAEDLGMITDEVHQLRDQLEFPGMRVFQFGFDSYDDPYHRPVAYPEQSVAYTGTHDNDTVMGWYHQRRQERHEDPLLDEVVHRDDPNPHHALIRAVLASRSDTAILPMQDVLGLGSDARMNVPGQAAGNWTWRCPPDGLDQHVSDWLRQVTEETGRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYB9</accession>
    <name>A0A518IYB9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative subtilase-type serine protease</fullName>
            <ecNumber evidence="3">3.4.21.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_40810</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.4.21.-" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
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        <property type="entry name" value="Peptidase_C_arc/bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04151">
        <property type="entry name" value="PPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPC" evidence="2">
        <location>
            <begin position="354"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="788"/>
            <end position="831"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="831" mass="89281" checksum="700C717237708448" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYD7</accession>
    <name>A0A518IYD7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_41110</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011453">
        <property type="entry name" value="DUF1559"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07596">
        <property type="entry name" value="SBP_bac_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="330" mass="36146" checksum="3128B4030027CF77" modified="2019-10-16" version="1">MVRKGFTLVELLVVIAIIGILVGLLLPAVQAAREAARRMQCSNNLKQIGLALHNYHDTYQSLPPGHVDVGGTMVNADPDYRWGWNAQILPFMEQQAVLDAIHFGNWNVRSCAADATTRAAMSNPISAYRCPSDVAPDTNNECPMASQRTATSNYIGVHNSDIWNGQACADNQERGGCFYGEGVVRFRDVLDGLSNTLMVGERKWQTRDKNGTLETSGAAHAFGIVRWNDWHRGYIYGVGVYRQNMDGLDFRNGSTNRTKQGFSSMHPGGAQWVSADGSVGFVANTIDANFDSRGVQADPSGSVVEANRRVIDTVWERLLARGDGQPVTRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYK1</accession>
    <name>A0A518IYK1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Sodium-dependent dicarboxylate transporter SdcS</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">sdcS_1</name>
        <name evidence="7" type="ORF">Mal33_41710</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031312">
        <property type="entry name" value="Na/sul_symport_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001898">
        <property type="entry name" value="SLC13A/DASS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00939">
        <property type="entry name" value="Na_sulph_symp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00785">
        <property type="entry name" value="dass"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01271">
        <property type="entry name" value="NA_SULFATE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="80"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="124"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="207"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="250"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="287"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="329"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="359"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="394"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="419"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="453"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV58154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="472" mass="49268" checksum="4CC01D52B9F2B20B" modified="2019-10-16" version="1">MMFSCPKSAMLPGGVVVAALVGAGCSSAGLEAPACWCAATATLCAMWWIFEVLPIAATALLPFIVFPLTGVLDHRTVATAYGHTMILLLMGGFLLSAAMERSGAHRRLAMIMVRAVGGRGERRIVLGFMLATAMLSMWISNTATTLMMLPIAMAVLERHACNGLRVPLLLGIAYSASVGGMGTPVGTPPNAMFMGFYEEKLGRSLAFVDWMVIAVPIVAILLPIIWLWLTRNLKSDAIFEMPDVGAWRSAEVRVLIVFSLTALAWITRTTPFDGWSYWIGATTPNDAGGITSLVGDSTVALAATLALFIIPSGGEAKGPLLDWETAERIPWGILLLFGGGLALAKGFDASGLSTVIGDSLAGLASLPPILVIGGVCLLVTFLTEITSGTATTALLLPILASTAIAADVPAEMIMIPGTISASCAFMLPVATAPNTIVYGAGGLSTGVMARTGLVLNLIAVCVITTFCWLMLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYS1</accession>
    <name>A0A518IYS1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Succinate-semialdehyde dehydrogenase [NADP(+)]</fullName>
            <ecNumber evidence="3">1.2.1.79</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">gabD_1</name>
        <name evidence="3" type="ORF">Mal33_42440</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.2.1.79" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004029">
        <property type="term" value="F:aldehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036243">
        <property type="term" value="F:succinate-semialdehyde dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044638">
        <property type="entry name" value="ALDH7A1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43521">
        <property type="entry name" value="PTHR43521"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="2">
        <location>
            <begin position="28"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="514" mass="54200" checksum="293D693B9258A004" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZZ7</accession>
    <name>A0A518IZZ7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="13">CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase</fullName>
            <ecNumber evidence="13">2.7.8.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">pgsA</name>
        <name evidence="13" type="ORF">Mal33_46910</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">Mal33</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="10">Phospholipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the CDP-alcohol phosphatidyltransferase class-I family.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.5" evidence="13"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00610">
        <property type="reaction ID" value="UER00666"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008444">
        <property type="term" value="F:CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000462">
        <property type="entry name" value="CDP-OH_P_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043130">
        <property type="entry name" value="CDP-OH_PTrfase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004570">
        <property type="entry name" value="Phosphatidylglycerol_P_synth"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01066">
        <property type="entry name" value="CDP-OH_P_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000847">
        <property type="entry name" value="Phos_ph_gly_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00560">
        <property type="entry name" value="pgsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00379">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="9" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 11 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="138"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="160"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="QDV58667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="197" mass="21604" checksum="C1A2921B629039FC" modified="2019-10-16" version="1">MTTATTTTTTPPSIYNVPNLLTTIRFFLAIGVVVLLAYQEYWSALVAFSVAAGTDWMDGYWARKYGQVTKLGRIFDPFVDKIIICGTFIALVAIDDSNVAPWMAIVIVARELLVTSLRGMIEGSGGDFSARWSGKWKMVLQCAAIILVLIGLGMRDAPAWILHATTLTLWSAVALTLYSGWEYILAATRMLRDGAKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0C6</accession>
    <name>A0A518J0C6_9BACT</name>
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        <submittedName>
            <fullName evidence="4">Thioredoxin-2</fullName>
            <ecNumber evidence="4">1.8.1.8</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">trxC</name>
        <name evidence="4" type="ORF">Mal33_47800</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.8.1.8" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047134">
        <property type="term" value="F:protein-disulfide reductase (NAD(P)) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005746">
        <property type="entry name" value="Thioredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01068">
        <property type="entry name" value="thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="3">
        <location>
            <begin position="3"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV58755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="138" mass="14773" checksum="1C37474BF04FAD03" modified="2019-10-16" version="1">MNFVCSACASVNRVPDSKLADGPICGRCKQPLLPSHPIDLTESSFAKFIAKTELPVLVDFWAPWCGPCRMMAPAFAEAAAQLSPKVLLAKLNTEQAPSTAGQFDITGIPTMILFKAGVPVARQSGAKNVQQIVQFANR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0F5</accession>
    <name>A0A518J0F5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Rhomboid protease GlpG</fullName>
            <ecNumber evidence="8">3.4.21.105</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">glpG_2</name>
        <name evidence="8" type="ORF">Mal33_48520</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="3.4.21.105" evidence="8"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038236">
        <property type="entry name" value="GlpG_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022732">
        <property type="entry name" value="Peptidase_S54_GlpG_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022764">
        <property type="entry name" value="Peptidase_S54_rhomboid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01694">
        <property type="entry name" value="Rhomboid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12122">
        <property type="entry name" value="Rhomboid_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="SSF144091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="113"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="179"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="209"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="234"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="265"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="290"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="domain" description="Rhomboid_N" evidence="7">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="domain" description="Rhomboid" evidence="6">
        <location>
            <begin position="166"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV58827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="318" mass="34757" checksum="4C9C8434A39472E9" modified="2019-10-16" version="1">MRKIGELTERAEAVRFCDYLLTIDISAMAETSHSDPQAWAIWIRDEDRLDEARTQFAAFREQPGDAKYNVQKQADEIRKQQEAKNKDRLKQQRKVGGAAWAGSGNFMTRKPRLTIGLVITCVVLFFITDPGAQRSGDDAGAQLFRALRFVGVQDYVESEGDPLASIKKGEIWRVFTPNLLHGSLMHLGFNMMALFFLGGAIERLQSPGAFALLVFLTGVTAIVLQSVFPESLGGSPNVIGISGAVYGLFGYLWIRPILQPTFPNLIPPSTVMLMMVFLFMFILLPQGSMGGVSVANVAHVAGLVTGIACAAVASRMPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0H3</accession>
    <name>A0A518J0H3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Pyrophosphate--fructose 6-phosphate 1-phosphotransferase</fullName>
            <ecNumber evidence="11">2.7.1.90</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">pfp</name>
        <name evidence="11" type="ORF">Mal33_48680</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>beta-D-fructose 6-phosphate + diphosphate = beta-D-fructose 1,6-bisphosphate + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13613"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="EC" id="2.7.1.90"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 3/4.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.90" evidence="11"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00182"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003872">
        <property type="term" value="F:6-phosphofructokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047334">
        <property type="term" value="F:diphosphate-fructose-6-phosphate 1-phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006002">
        <property type="term" value="P:fructose 6-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.460">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022953">
        <property type="entry name" value="ATP_PFK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000023">
        <property type="entry name" value="Phosphofructokinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035966">
        <property type="entry name" value="PKF_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011403">
        <property type="entry name" value="PPi-PFK_TM0289"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00365">
        <property type="entry name" value="PFK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036482">
        <property type="entry name" value="PPi_PFK_TM0289"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00476">
        <property type="entry name" value="PHFRCTKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53784">
        <property type="entry name" value="SSF53784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PFK" evidence="10">
        <location>
            <begin position="7"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QDV58843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="423" mass="46445" checksum="657C8F066EECF91F" modified="2019-10-16" version="1">MTQEIKRVAILFAGGPAPAANSVIATAASSFMKEGIEVYGIKHGYSRLAEYTASGPMREGVDYIKFTHEMLAHARTSRGIMIGTARTNPGKHVSSPEHLDDAELSAPLRRVYEGLVSMGVDALISIGGDDTLKTANKIKMFQDRLPEDAKKFPVVHLPKTIDNDYMGIDFTFGYFTAVETLAEEIRNLNYDASAGRAYFICEAMGRSAGWLAYGAAIAGEASMVLSVEDIAGSLRGEEVINAETGETRPVMEIDRVIDRMVDMMLARERQGREYGVIVIAEGLAEFLPSKNLEGIDRDEHGHIAISQINLGAMISGLLTRRYEERTGKTRKVNGLQLGYECRCAPPHAFDVMLGSQLGVGAYRALKEEKLNGVMVSVSGQLDLHFVPFDNLVDPKTLVTKVRFIEGDSDFYKLARFLETCVED</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0I9</accession>
    <name>A0A518J0I9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Alpha-amylase 1</fullName>
            <ecNumber evidence="5">3.2.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">amyA</name>
        <name evidence="5" type="ORF">Mal33_48400</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 57 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.1" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003844">
        <property type="term" value="F:1,4-alpha-glucan branching enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004556">
        <property type="term" value="F:alpha-amylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030979">
        <property type="term" value="P:alpha-glucan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015179">
        <property type="entry name" value="A-amylase/a-glucTrfase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015178">
        <property type="entry name" value="A-amylase/a-glucTrfase_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040042">
        <property type="entry name" value="Branching_enz_MT3115-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028995">
        <property type="entry name" value="Glyco_hydro_57/38_cen_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004300">
        <property type="entry name" value="Glyco_hydro_57_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41695">
        <property type="entry name" value="PTHR41695"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09094">
        <property type="entry name" value="DUF1925"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09095">
        <property type="entry name" value="DUF1926"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03065">
        <property type="entry name" value="Glyco_hydro_57"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="SSF74650"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88688">
        <property type="entry name" value="SSF88688"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="SSF88713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_hydro_57" evidence="2">
        <location>
            <begin position="44"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1925" evidence="3">
        <location>
            <begin position="315"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1926" evidence="4">
        <location>
            <begin position="414"/>
            <end position="700"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF09095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV58815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="724" mass="82226" checksum="E1E0EC6D7A6C2E0E" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0R1</accession>
    <name>A0A518J0R1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">GTP pyrophosphokinase rsh</fullName>
            <ecNumber evidence="1">2.7.6.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rsh</name>
        <name evidence="1" type="ORF">Mal33_49560</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.6.5" evidence="1"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008728">
        <property type="term" value="F:GTP diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="163" mass="17983" checksum="1D85447B976F78D5" modified="2019-10-16" version="1">MHTNVQAAREFALRAHGSQQYGEHPYSYHLDAVAALLEPFGDQAQVAAYLHDTVEDTSATNEEIEASFGQPMAETVALLTDEEGDTRSARKAKTNAKLAATNNTLALTVKAADRLANLLECQRGSCGKLEMYRREHEAFRKAAYRDGLSEDLWQRIDAIIAGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0Z3</accession>
    <name>A0A518J0Z3_9BACT</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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    <organism evidence="1 2">
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    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
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                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
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                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="64" mass="7462" checksum="DE50EB90F57CBC61" modified="2019-10-16" version="1">MAKKTATEEGFRLDEYNTPIAIHADSRDRQRWWVHFDGKRNVFGHHLSVCITEGTEDAEVYLGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J117</accession>
    <name>A0A518J117_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Addiction module component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_50530</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="entry name" value="CHP02574_addiction_mod"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09720">
        <property type="entry name" value="Unstab_antitox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02574">
        <property type="entry name" value="stabl_TIGR02574"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="69" mass="7793" checksum="7C37E281A2833E4B" modified="2019-10-16" version="1">MTLQESLRSLPPDQKLAIVTQLWDDLASSAPLTLPSDELAEMQRRRDEMLADPSIAIDADEVWRRVDGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J143</accession>
    <name>A0A518J143_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytochrome c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Mal33_50820</name>
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    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Rosistilla</taxon>
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    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012938">
        <property type="entry name" value="Glc/Sorbosone_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013427">
        <property type="entry name" value="Haem-bd_dom_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011041">
        <property type="entry name" value="Quinoprot_gluc/sorb_DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13442">
        <property type="entry name" value="Cytochrome_CBB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07995">
        <property type="entry name" value="GSDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="CxxCH_TIGR02603"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
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        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021920018" evidence="5">
        <location>
            <begin position="23"/>
            <end position="1038"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="6">
        <location>
            <begin position="47"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="6">
        <location>
            <begin position="225"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV59057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1038" mass="114689" checksum="F446F640F1844E36" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J149</accession>
    <name>A0A518J149_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">Mal33_50910</name>
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    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Rosistilla</taxon>
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    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022071524" evidence="1">
        <location>
            <begin position="22"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="313" mass="34411" checksum="2C3E346C1759962E" modified="2019-10-16" version="1" precursor="true">MMKSAALLAVLVAFLSSSTDASDQETTHSFLACGQKTYIMDDDGKVSWTYPASTRDGYVLRDGTVVLTLSKSERYRGGAVVKIAPDKTETLLWEGTQSEINSAQPTPDGNFVITEAGNKPRLLEIDSEGEIVLEFPLACQMKNHHMQTRMARKLADGTFLAPHLLDFAVFHYGNDGEVLNKLDTTVPGDTEHKIHSWPFTAIRHGDGHTLVCCTNGNRVVDFDSDGKIVWTLTNDDLPGAWLQDPCGSQVLPGGNIVITSYAAGRKDPNAPKLFEVTRDKKVVWKYVDGQKVGIHHFQLLTTNGKRLQGPVLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J189</accession>
    <name>A0A518J189_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative diguanylate cyclase AdrA</fullName>
            <ecNumber evidence="3">2.7.7.65</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">adrA_2</name>
        <name evidence="3" type="ORF">Mal33_51230</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.7.65" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052621">
        <property type="term" value="F:diguanylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GGDEF" evidence="2">
        <location>
            <begin position="208"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="143"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV59098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="346" mass="38200" checksum="1535EE62013EEB48" modified="2019-10-16" version="1">MPEPGPNENLDAFAIAKDALRLIGQFKTPPTPNVYRVWYRYVEGQDQELVRQLQPAVNDARSVSVGMLESLHSQSPDVVDDTNANIGEALVAELSRFQNLLSQQQAAGDEFEGTIDTASKLLNTNSPSDKNSADCIAVINAGAALMKGQLTEASDKLAAAKNQIAKLQTELAQSRRGMMTDHLTGIGNRRYFDAHVRQTLQSLEYCSGAVYLILMDVDHFKNINDSFGHDAGDQVIRFIASETSRRHPNVSLSRLGGDEFAVILQTNSSLEAAEFADELRKFFATQKLKIMPSRTPMGSIRISMGLARLRVDDNEQSWYTRADAMLYRAKGAGRDQVAIEEECMPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1A0</accession>
    <name>A0A518J1A0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF4062 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_51340</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025139">
        <property type="entry name" value="DUF4062"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13271">
        <property type="entry name" value="DUF4062"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4062" evidence="1">
        <location>
            <begin position="7"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="352" mass="40378" checksum="B2289001681271D7" modified="2019-10-16" version="1">MHDKRYQIFISSTYDDLKVERSEVMQALLELDCMPGGMELFPSANEEQWNWIRKVIDESDYYLVIVANRYGSVSDQTGMSYTEMEYRYAADIGKPTIAFLHEDPTGIEAKRSEQSQTGKRKLAQFRKLCETRLVKYWNSPVDLGAKVSRSLTQLIKHEPAIGWVRADKIPEDQSAVILRLRDEISGLKSKLKESSARSRAPDNLACGTDQVEIDFSYQTKKAKTGKNGQAYWVNDDEHDGSLRTTWDDLFSCLAPDLINPASEYRIVSCINNFIEGRTHFKMQEMHPDKKIETIRIYSNVLDQIKVQLRALGLIEIEYGNDWVLTEHGDQHMIELLAQKKAEPSCEPVRPTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1C5</accession>
    <name>A0A518J1C5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_51410</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010869">
        <property type="entry name" value="DUF1501"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07394">
        <property type="entry name" value="DUF1501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="450" mass="49412" checksum="0305E6B242B75FA0" modified="2019-10-16" version="1">MNSIEPTRRQCLRSLIGSSILFPAVLSDLAAAEAPAVGPLTPKAPHFPAKAKRVIMVFATGGVSHIDSFDPKSSEKGRDGSGKDKLMGCVFPTNADKKTGTVVSDLFPHLRDSMEDICLIRSMKSAHFDHTEAAVGMHTGSPTFARPSMGSWLSYGLGTVNQNLPSFIVIAPHLPYGGTQVYASDFLPAYHQGTRVIPGTEPIANLAPRTTREKIQQMELSLVDSLNQKHLESRRDDSQLAARIKSYETAFQMQTAGPEAFDLSKEDEPTLSMYGLKPGETSSFAWQCIIARRLAERGVRFIELVDSGSRPNWDSHGDMKEHQPLAKASDQPLAALIQDLKQRGMLDETLIVWATEFGRTPTKEGKFGRGHHGDCFSIWLAGGGVEAGFVLGETDELGKAIVRDKIDVHDLHATILHQMGIDHKRLTYRHAGRDFRLTDVHGRIVKEILA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1H8</accession>
    <name>A0A518J1H8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Riboflavin biosynthesis protein RibD</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="10">Diaminohydroxyphosphoribosylaminopyrimidine deaminase</fullName>
                <shortName evidence="10">DRAP deaminase</shortName>
                <ecNumber evidence="10">3.5.4.26</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="10">Riboflavin-specific deaminase</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="10">5-amino-6-(5-phosphoribosylamino)uracil reductase</fullName>
                <ecNumber evidence="10">1.1.1.193</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="10">HTP reductase</fullName>
            </alternativeName>
        </domain>
    </protein>
    <gene>
        <name evidence="15" type="primary">ribD</name>
        <name evidence="15" type="ORF">Mal33_52060</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 10">Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine + H(+) + H2O = 5-amino-6-(5-phospho-D-ribosylamino)uracil + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:21868"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:58453"/>
            <dbReference type="ChEBI" id="CHEBI:58614"/>
            <dbReference type="EC" id="3.5.4.26"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>5-amino-6-(5-phospho-D-ribitylamino)uracil + NADP(+) = 5-amino-6-(5-phospho-D-ribosylamino)uracil + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:17845"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58421"/>
            <dbReference type="ChEBI" id="CHEBI:58453"/>
            <dbReference type="EC" id="1.1.1.193"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10 13">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="10 13">Binds 1 zinc ion.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Cofactor biosynthesis; riboflavin biosynthesis; 5-amino-6-(D-ribitylamino)uracil from GTP: step 2/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 10">Cofactor biosynthesis; riboflavin biosynthesis; 5-amino-6-(D-ribitylamino)uracil from GTP: step 3/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 10">In the C-terminal section; belongs to the HTP reductase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.26" evidence="10"/>
    <dbReference type="EC" id="1.1.1.193" evidence="10"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00275">
        <property type="reaction ID" value="UER00401"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008703">
        <property type="term" value="F:5-amino-6-(5-phosphoribosylamino)uracil reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008835">
        <property type="term" value="F:diaminohydroxyphosphoribosylaminopyrimidine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.430.10">
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="APOBEC/CMP_deaminase_Zn-bd"/>
    </dbReference>
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        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
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        <property type="entry name" value="DHFR-like_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="Eubact_RibD"/>
    </dbReference>
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        <property type="entry name" value="RibD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002734">
        <property type="entry name" value="RibDG_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01872">
        <property type="entry name" value="RibD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006769">
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    </dbReference>
    <dbReference type="SUPFAM" id="SSF53597">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF53927"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00227">
        <property type="entry name" value="ribD_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00903">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 10 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="10 12" id="KW-0521">NADP</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0686">Riboflavin biosynthesis</keyword>
    <keyword evidence="8 10 13" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="14">
        <location>
            <begin position="7"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="11">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="162"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="178"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="208"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="212"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="215"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="301"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
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        <location>
            <begin position="303"/>
            <end position="309"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004910"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00007417"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022619"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR006769-2"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="QDV59178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="372" mass="39669" checksum="AD0B36826ED7B110" modified="2019-10-16" version="1">MTQRILPNDQQWMRHALALAARGKGFVEPNPMVGCVIVRDGKPLAEGYHEKFGGPHAERQALAALPADCDPAGATWYVTLEPCCHTGKTPPCSDAVIAARPQRVVIAAVDPFSEVAGGGIAQIRAAGIDVEVGVCEAEANRLNAPFIKRVRQQKSWVIAKWAMTLDGKIATHSGNSQWISGEASRRRVHEVRGQVDAIVTGIGSVLADDPTLTARPPGPRTAARIVLDDKAELPLNSTLIKTRETAPVYAVVRSDAPQQRIDALRKAGVGVIVNESRTRSGGVEQLLTWCHDQGMTNLFLEAGAGAMASFFEADAIDEYHVYVAPKLIGGSAAPGPLGGQGLATIAESPAMEPLQVESIDGDLFITTRRTNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1I6</accession>
    <name>A0A518J1I6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_52340</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Pirellulaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="321" mass="34803" checksum="2D43B6AA79093C05" modified="2019-10-16" version="1">MRNRSIRSGFTLVELLVVIAIIGILVGLLLPAVQAAREAARRMQCTNNVRQIGLACHNYHSTLRRMPPGRLVYDGTNSAGAPTKVVTGFLAMLLPYMEGSNLHDIYDQTYGFDDVANQTAVNMEVPAFTCPSTPGDRTMPIYAGWNMGWTTDPAALDPNLTGFETSYQGVRGIHRLQGDPLVSGFDSDCGILNETGSRFADITDGTSNTLLLFEMTGKPSHWLLGKQQPSVTNAQFYAYGPWAGNNGIGIYNWSDDGLSKGCNTCTKYINVDNTASPYGFHPGVVAIVLADGSTRTLAETVDAEIFINLCRKQDGNVVGDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1J3</accession>
    <name>A0A518J1J3_9BACT</name>
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        <submittedName>
            <fullName evidence="2">Transcriptional repressor MprA</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="primary">mprA_5</name>
        <name evidence="2" type="ORF">Mal33_52330</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
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                <person name="Devos D.P."/>
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                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="GO" id="GO:0003700">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00598">
        <property type="entry name" value="HTHMARR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="19"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="167" mass="18994" checksum="6CFB2995B4D7224F" modified="2019-10-16" version="1">MATPTNSPTSQKVGFDSPEQEVFLQLWRTYDCLKTLEEQLFAQHDLSPQQYNALRLLQQVAPAGMQTMELGRQLISRAPDTTRMLDRLQKRGLIARNRRAENRRVVEIALTEAGHALLAELSGSVLQMHHQQLGHLDASQRGDLIDLLKRARRPHEDSSCDWLEDGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1J4</accession>
    <name>A0A518J1J4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">BNR/Asp-box repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_52410</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011040">
        <property type="entry name" value="Sialidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036278">
        <property type="entry name" value="Sialidase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13088">
        <property type="entry name" value="BNR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50939">
        <property type="entry name" value="SSF50939"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021978177" evidence="1">
        <location>
            <begin position="26"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="domain" description="Sialidase" evidence="2">
        <location>
            <begin position="53"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV59213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="382" mass="42290" checksum="FB506FD70573F476" modified="2019-10-16" version="1" precursor="true">MRKWNISSAACVGTVVAWLCSVAVAGDSIPTVDISSESDRHSFVARGTTEVYQGHPCTVLLPDGKTMFCAWSINHAGFLGPLSRSDDGGKTWSQPLAVPGNWRQVTKTTPTLHRLVDPEGVARLFVFGGCDFPGRLRQAYSEDNGKTWTPMRDTGLAAECAPKTVMAFDDGKRLVMWCDRRGPFAANQPHADPYIWQAESLDGGLTWSPEQPVLKTESRWGQPAVVRSPDGNQLLMLLRNEESHSLFSVSDDDGKTWAPVRPLPATLTGHRHKILYAPDGRLVVVMRNKDAESQSHGHFVAWVGTYDDILAGRDGQYRIKLLHSHARWDCGYSGFELLSDGTFVATTYIKYKPGPEKHSVVTTRFKITETDHKLADAKKLVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1P2</accession>
    <name>A0A518J1P2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">TVP38/TMEM64 family membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ydjZ</name>
        <name evidence="3" type="ORF">Mal33_52800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TVP38/TMEM64 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032816">
        <property type="entry name" value="SNARE_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015414">
        <property type="entry name" value="TMEM64"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12677">
        <property type="entry name" value="PTHR12677"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09335">
        <property type="entry name" value="SNARE_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="62"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="99"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="177"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="219"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU366058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV59252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="257" mass="27935" checksum="A5932D2C21D4BA76" modified="2019-10-16" version="1">MTTDSEPQDESKPSGIGMKIGLLVLVIAIIAIAYTQFGDLLSLENLAKQEAQLRAFQSDHPVLVYGAAFLIYVAVAGLSLPGAAVLTLVYGWYFGLARGVVLVSFASTAGATVAFLLSRFLFRDSIQKRFGKRLENFNQSLEKEGPFFLFTLRLIPAVPFFVINAVMGLTPIHVRTFWWVSQLGMLAATVVYVYAGASVPNLQTLADSGIGAVFSPSQLSQIVFAFVLLGLFPLIVRFAMKFIHRGTPQHAVDSPAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1T6</accession>
    <name>A0A518J1T6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Acetolactate synthase small subunit</fullName>
            <shortName evidence="8">AHAS</shortName>
            <shortName evidence="8">ALS</shortName>
            <ecNumber evidence="8">2.2.1.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Acetohydroxy-acid synthase small subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ilvH</name>
        <name evidence="10" type="ORF">Mal33_53280</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>H(+) + 2 pyruvate = (2S)-2-acetolactate + CO2</text>
            <dbReference type="Rhea" id="RHEA:25249"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:58476"/>
            <dbReference type="EC" id="2.2.1.6"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 1/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 8">Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 1/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 8">Dimer of large and small chains.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 8">Belongs to the acetolactate synthase small subunit family.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.6" evidence="8"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00047">
        <property type="reaction ID" value="UER00055"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00049">
        <property type="reaction ID" value="UER00059"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003984">
        <property type="term" value="F:acetolactate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990610">
        <property type="term" value="F:acetolactate synthase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04878">
        <property type="entry name" value="ACT_AHAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004789">
        <property type="entry name" value="Acetalactate_synth_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027271">
        <property type="entry name" value="Acetolactate_synth/TF_NikR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019455">
        <property type="entry name" value="Acetolactate_synth_ssu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039557">
        <property type="entry name" value="AHAS_ACT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30239">
        <property type="entry name" value="PTHR30239"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01842">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10369">
        <property type="entry name" value="ALS_ss_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00119">
        <property type="entry name" value="acolac_sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7 8" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ACT" evidence="9">
        <location>
            <begin position="26"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU368092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV59300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="189" mass="20950" checksum="4C818F723C5FAED9" modified="2019-10-16" version="1">MMRSFLARPGFSLDSTTVQKHNMRHVLSALVQNVPGVLAHISGMLASRGYNIDSLAVGETDDPHLSHMTFVVVGDEKTLAQVRKQLEKIVTVVRVMDISATDFVERDLMLCKVQAAPGPSRSEVRELVDIFRGRIVDVGPDEITIEMSGRESKVEAFIERMRTYGIIELVRTGRIAMVRSGAVSEEPVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1U9</accession>
    <name>A0A518J1U9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_53430</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="431" mass="48918" checksum="009810ED2BF2CF23" modified="2019-10-16" version="1">MEDPVKSPYERRKILFLSEFLPSHHGHGGNVYPYFVLTGLRAQAVDHVTLVPDAMASFGKPWCSHACKFKSDGWVNIGSTSVSTKPKHWFRFFAQRLRSVLKKLLRRNFAASVHAVPKSPRLATTDCESAKPLRPRLAKGLEDYLVRLQPHVLMVNFPYLIDSLSDQILQRHYVVTLTHELIHERVEAYQDQDWKLDFQPLSRSQEKRLLSRSQLVTAISEDDRKKLKQMLPHNEVVTCFPPIYESNHERVFSTPRAPHELTFLFIGSGAVHNRETMRWILDEIWPKVSARYPKMKFHIAGSVCQHAQDFASVSSVKLLGRVPEATDAYRDADIAFAFAISGAGVKMKLLEAIRFGVPALVTEETLRGLPVGAKDVFPTVFSASDLLKLIGDFFIGNTTLTELQNRQQSWADTQLQPKNLIQPLLNSLPLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J226</accession>
    <name>A0A518J226_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NADPH-dependent 7-cyano-7-deazaguanine reductase</fullName>
            <ecNumber evidence="1">1.7.1.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">7-cyano-7-carbaguanine reductase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">NADPH-dependent nitrile oxidoreductase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">PreQ(0) reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1 2" type="primary">queF</name>
        <name evidence="2" type="ORF">Mal33_54090</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>7-aminomethyl-7-carbaguanine + 2 NADP(+) = 7-cyano-7-deazaguanine + 3 H(+) + 2 NADPH</text>
            <dbReference type="Rhea" id="RHEA:13409"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:45075"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58703"/>
            <dbReference type="EC" id="1.7.1.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">tRNA modification; tRNA-queuosine biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.7.1.13" evidence="1"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00392"/>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046857">
        <property type="term" value="F:oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033739">
        <property type="term" value="F:preQ1 synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008616">
        <property type="term" value="P:queuosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00818">
        <property type="entry name" value="QueF_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043133">
        <property type="entry name" value="GTP-CH-I_C/QueF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029500">
        <property type="entry name" value="QueF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016856">
        <property type="entry name" value="QueF_type1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14489">
        <property type="entry name" value="QueF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF027377">
        <property type="entry name" value="Nitrile_oxidored_QueF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03139">
        <property type="entry name" value="QueF-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="1 2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1" id="KW-0671">Queuosine biosynthesis</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="1">
        <location>
            <begin position="56"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="1">
        <location>
            <begin position="75"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="active site" description="Thioimide intermediate" evidence="1">
        <location>
            <position position="34"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="121" mass="14043" checksum="EAA3EAFA7DF08D4F" modified="2019-10-16" version="1">MSTDFGDLLETFDNPYAGRNYTIEHTCPEFTSVCPKTGQPDFGTLVFTYVPNELCIELKSLKMYLQRYRNEGIFYEHITNRIMDDFVNAVKPRWANLESRWTPRGGLSSVIVVEYPDSEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J280</accession>
    <name>A0A518J280_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulatory protein BasR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">basR</name>
        <name evidence="5" type="ORF">Mal33_54800</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="2"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="4">
        <location>
            <begin position="123"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="123"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV59445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="217" mass="24484" checksum="489A46009C2ED18D" modified="2019-10-16" version="1">MRVLVVEDEPGLRDAVAMSLREEHYAVDEAADGRTGLQKARQWSYDAIVLDLMLPEIDGWELLAQLRKTHATPVLILTARDTVEDRVRGLDRGADDYLCKPFSLSELSARVRALIRRSHGQAKAEIVIGSVVINTANRTVEKEGRSVDLTAREYTLVELLALNRGELVSRSTVYDHVFDENEDSLSNLVDVHIYNIRKKLGKNFVTTRRGHGYIIET</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J2A8</accession>
    <name>A0A518J2A8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Bacterial Ig-like domain (Group 2)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Mal33_55100</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011444">
        <property type="entry name" value="DUF1549"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022655">
        <property type="entry name" value="DUF1553"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07583">
        <property type="entry name" value="PSCyt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07587">
        <property type="entry name" value="PSD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="2 3" id="KW-0408">Iron</keyword>
    <keyword evidence="1 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022109807" evidence="5">
        <location>
            <begin position="22"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="6">
        <location>
            <begin position="494"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="554"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="556"/>
            <end position="572"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV59475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="840" mass="92151" checksum="309E5F7353CF3EA8" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J2C9</accession>
    <name>A0A518J2C9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Serine/threonine-protein kinase PrkC</fullName>
            <ecNumber evidence="4">2.7.11.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">prkC_15</name>
        <name evidence="4" type="ORF">Mal33_55290</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.11.1" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="323"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="3">
        <location>
            <begin position="1"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="510"/>
            <end position="537"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV59494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="548" mass="61431" checksum="87E6FB04ED01B591" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ILV3</accession>
    <name>A0A518ILV3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Conjugal transfer protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_00210</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GSP E family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
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        <property type="entry name" value="T2SS/T4SS"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T2SP_E" evidence="2">
        <location>
            <begin position="90"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="449" mass="50093" checksum="BBAB1CB4138768B4" modified="2019-10-16" version="1">MNQATLSPSNSIERRERLQRVRGEIHDQLVARIDMSALRNIKPELMREQLRLGAQELCRFHSDLLTHAEQEEIVEDLLYEMLGLGPIEVLMNDPTISDILINGPSSVFVERRGMLEETQVRFQSLDHLVNIVQRVASRVGRRIDESSPMVDARLPDGSRLNAVIRPLALEGALVSIRKFATRPMTAADFVKRRVATPEMLGFLAACIAAKLNIVISGGTGSGKTTLLNMLSSHIPKGERIATIEDAAELQLQQSHVARMETRPANLEGRGEVTASDLLKNALRMRPDRIIIGECRGVEAFDMLQAMSTGHAGSMTTIHSNDTRDAINRLEMLVGMAAPELPMWFVHRQIASSINIVIQTHRMAGGTRKITQISEITGTQNDAINMHDLFTFQQTGVGENGQVEGHFEASGIMPKCLPRLRSAGVHIDADMFRQRRMEVDIDQMQEYRIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IM29</accession>
    <name>A0A518IM29_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_00800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041289">
        <property type="entry name" value="Bact_RF_family3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18845">
        <property type="entry name" value="baeRF_family3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="367" mass="39857" checksum="A3C2CF1B675109C7" modified="2019-10-16" version="1">MSTTTQETTLRTLKASDLKELANVCADPCVSILLPTHRTGREVQQAAIRLKNLLAQASDQLKSAGHDCSILDPVVSLSTTTDFWQHQADGLAIYLTTDQLWAFQLPHSVKERSCVGDSFFLSPLAPQHSRDGHCFALTLTWDEAKLYRCDGESMELVETDLLPAKFHDLVLPRDPEENLQNTSHRSVADTPGTSTAMFHGHGEGEDKIQADRQQYLTRVDDLVSSAVYNSNLPLVVVATKEVGGHFAATTDLTIDAKIDGSPARWSDDKLNEQVGQAISDPSAQEQANFAERFGTAAAQSLASSDISEVVFAAKHGRIESVMVSESEAVDDLVNLVVVQTLRHGGSVLRGCHDSMPDGGAVAAIYRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IM97</accession>
    <name>A0A518IM97_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_01670</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="177"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="202"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="216" mass="23177" checksum="D68823BE127ED22C" modified="2019-10-16" version="1">MVAGGLSAANTTGTNHVIDRPPPTGSHIYLRSLRERHALCPRIPEGAAARRPPATFCGPSGSVAPDKIAANRCHRIPQGSQTVAGGLSVANTTGTNRVIESPPPTGSHIHLRSLRERCALEPRIPEGAAARRPPATFCGPFGSVVPDKIAARRCHRIPTGSQTVAGGLSEYHRYKSRYRSPAPDGVVQRPAIPSGALRRTKSQRVDATESRRDRRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IM98</accession>
    <name>A0A518IM98_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DDE_3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_01710</name>
        <name evidence="4" type="ORF">Mal33_08860</name>
        <name evidence="5" type="ORF">Mal33_14930</name>
        <name evidence="6" type="ORF">Mal33_21030</name>
    </gene>
    <organism evidence="3 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 7">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038717">
        <property type="entry name" value="Tc1-like_DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13358">
        <property type="entry name" value="DDE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0814">Transposable element</keyword>
    <feature type="domain" description="DDE_3" evidence="2">
        <location>
            <begin position="39"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV54920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV55516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV56124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="231" mass="27140" checksum="32B6F24C306FC644" modified="2019-10-16" version="1">MTNRKIQYWVIPPDADSEFVACMEEVLDTYEEPYDSDYPVVCMDEQPVQLHKETRTPIPATRNHARRVDYEYERCGTASVFMFTEPLAGWREVTVRPKRTKVDWAIEMEALLTTRYKKAKKIILVCDNLNTHTKGAFYEAFKPEKARALVRRIEFRYTPKHGSWLNAAENELSSMTRQCINGRRFATIAPLRKETQAWSSHSNRRQRGVDWQFQVKDARTKLKSLYPKIKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMD3</accession>
    <name>A0A518IMD3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">HlyD family secretion protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_01990</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990961">
        <property type="term" value="P:xenobiotic detoxification by transmembrane export across the plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030196">
        <property type="entry name" value="MdtN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039562">
        <property type="entry name" value="MFP_biotin_lipoyl_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30367:SF1">
        <property type="entry name" value="PTHR30367:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13533">
        <property type="entry name" value="Biotin_lipoyl_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Biotin_lipoyl_2" evidence="2">
        <location>
            <begin position="549"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="210"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="818" mass="89722" checksum="CB43A61DBA0B23B2" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMM2</accession>
    <name>A0A518IMM2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Xylose operon regulatory protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">xylR_2</name>
        <name evidence="2" type="ORF">Mal33_02940</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="1">
        <location>
            <begin position="281"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="383" mass="43222" checksum="9F832F8427863434" modified="2019-10-16" version="1">MKRHVALIVETSSIYGRQVLSGIIQHMRMFDDWSVFLDQHDLTQEPPRWLANWAGDGIISRTTTPELLQTVQATGVPLIELTDRHQSHGRTYVWSDDAAIGRMAAEHLLERGFREFGFCGFTNEAWSERRQDAFSQRVEAAQRRCHQYESPWYGPDALSWEEEQQRLRAWLRTLPSSCGIMACNDLRGQQVVDACLQEGLSVPEEVAIIGADNDTLLCRVCSPPMSSVIPNAEGVGFRAAELLTQLMNGEVPQKTEHLIQPLGVAERQSTDVVAIDDPDIAAALRYIRENACRGINVVDVTDNVAISRSSLERKLRQYLSRTPQQEIRHVQIKRVCELLTSTELPAEQIATLCGFDNPEYMYVVFRRIVGMTPGKFRSKAKPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMT3</accession>
    <name>A0A518IMT3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Probable membrane transporter protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Mal33_03530</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002781">
        <property type="entry name" value="TM_pro_TauE-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01925">
        <property type="entry name" value="TauE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="51"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="107"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="147"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="187"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="236"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV54399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="258" mass="27356" checksum="F568C93EE34EA0C5" modified="2019-10-16" version="1">MKESIYEMQQLAWYVVLIAAGFIAGIINTIAGGGSFLTLPALMLFGLDPKIANGTNRVAVLFSSASAVATFNKHGYLNRSLALELTIPTLAGVPVGALLAIYLPSGIFEAIFGVIFLCMAVLIAMNPKRLIETRQASDRSRWVTSPLFFAIGIYVGFIQAGMGILLLMAMSLLNTGDLLASNAIKNLIGFLVTLAAVGLFAVYGYIEWLPGLAMAMGNVVGGVVGAKLAIKKGNRLIFVFLIVVMTASGVKMIWSSLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMY6</accession>
    <name>A0A518IMY6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Imidazoleglycerol-phosphate dehydratase</fullName>
            <shortName evidence="5">IGPD</shortName>
            <ecNumber evidence="5 6">4.2.1.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">hisB</name>
        <name evidence="7" type="ORF">Mal33_04050</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + H2O</text>
            <dbReference type="Rhea" id="RHEA:11040"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57766"/>
            <dbReference type="ChEBI" id="CHEBI:58278"/>
            <dbReference type="EC" id="4.2.1.19"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 5 6">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 6/9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5 6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the imidazoleglycerol-phosphate dehydratase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.19" evidence="5 6"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00011"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004424">
        <property type="term" value="F:imidazoleglycerol-phosphate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07914">
        <property type="entry name" value="IGPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00076">
        <property type="entry name" value="HisB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038494">
        <property type="entry name" value="IGPD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000807">
        <property type="entry name" value="ImidazoleglycerolP_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020565">
        <property type="entry name" value="ImidazoleglycerP_deHydtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23133">
        <property type="entry name" value="PTHR23133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00475">
        <property type="entry name" value="IGPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00954">
        <property type="entry name" value="IGP_DEHYDRATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00955">
        <property type="entry name" value="IGP_DEHYDRATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5 6" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="4 5 6" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV54451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="196" mass="21445" checksum="79285CE36C701506" modified="2019-10-16" version="1">MTRAASIQRKTGETDISLSIDLDGQGAGTRTTGVGFLDHMLDLFARHGLIDLTVDASGDLEVDDHHTTEDVGICLGQAIDKALGDRAGIRRYGHFTLPMDETLVTVAIDFSGRYAFEYRAPIANPKLGSFDSELIEHFWQSFAANTRCNLHVLMHYGRNSHHIAEAVFKATARAVRMAVEVDPRVQGVMSTKGSLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IN00</accession>
    <name>A0A518IN00_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RNA polymerase sigma factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_04060</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014331">
        <property type="entry name" value="RNA_pol_sigma70_ECF_RHOBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02989">
        <property type="entry name" value="Sig-70_gvs1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="2">
        <location>
            <begin position="28"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="180" mass="20269" checksum="A75FF5B4238B2FEF" modified="2019-10-16" version="1">MQPELPHPPSDAEFVGLLTQSQLSLLLYVRSLMPGEADAGDVAQQANAKIWEKRADFALGTNFLAWSFAIARFEVLNYRKRRARDSRLTFSEDLEQTITSELQQIDDDLLSRQEALRKCLDGLKPESRTLLMDRYGTTESLADFARRIGRSAGGLKVSLHRIRTTLADCIERRLVSGASQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INA1</accession>
    <name>A0A518INA1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Corrinoid adenosyltransferase</fullName>
            <ecNumber evidence="4">2.5.1.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Cob(II)alamin adenosyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Cob(II)yrinic acid a,c-diamide adenosyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Cobinamide/cobalamin adenosyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">yvqK</name>
        <name evidence="6" type="ORF">Mal33_05290</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>2 ATP + 2 cob(II)alamin + reduced [electron-transfer flavoprotein] = 2 adenosylcob(III)alamin + 3 H(+) + oxidized [electron-transfer flavoprotein] + 2 triphosphate</text>
            <dbReference type="Rhea" id="RHEA:28671"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16304"/>
            <dbReference type="ChEBI" id="CHEBI:18036"/>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="EC" id="2.5.1.17"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>2 ATP + 2 cob(II)yrinate a,c diamide + reduced [electron-transfer flavoprotein] = 2 adenosylcob(III)yrinate a,c-diamide + 3 H(+) + oxidized [electron-transfer flavoprotein] + 2 triphosphate</text>
            <dbReference type="Rhea" id="RHEA:11528"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18036"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="ChEBI" id="CHEBI:58503"/>
            <dbReference type="ChEBI" id="CHEBI:58537"/>
            <dbReference type="EC" id="2.5.1.17"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Cofactor biosynthesis; adenosylcobalamin biosynthesis; adenosylcobalamin from cob(II)yrinate a,c-diamide: step 2/7.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the Cob(I)alamin adenosyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.17" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00148">
        <property type="reaction ID" value="UER00233"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008817">
        <property type="term" value="F:cob(I)yrinic acid a,c-diamide adenosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016030">
        <property type="entry name" value="CblAdoTrfase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036451">
        <property type="entry name" value="CblAdoTrfase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029499">
        <property type="entry name" value="PduO-typ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12213">
        <property type="entry name" value="PTHR12213"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01923">
        <property type="entry name" value="Cob_adeno_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89028">
        <property type="entry name" value="SSF89028"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00636">
        <property type="entry name" value="PduO_Nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Cob_adeno_trans" evidence="5">
        <location>
            <begin position="12"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU366026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV54574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="197" mass="21512" checksum="164D5BAA9ADF4D41" modified="2019-10-16" version="1">MMLNKEQHKMKIYTRTGDAGMTGLFAGPRVSKDDLRIESFGTVDELNSVLGVARSHPIDADIADQLEQVQADLFTVGARLATTQPERLKIRLVGDADVQRLEDWIDAHEESLPALEHFILPGGSVAAASVHHARTVGRRAERLVVGLVAAYPNEGYEVVGIYLNRLSDYLFVLARAINHRGGVADSIWIGEPSSPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INB9</accession>
    <name>A0A518INB9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_05350</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="139"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="191"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="237" mass="26919" checksum="45CDB2CD36EFFE51" modified="2019-10-16" version="1">MNTTPPHGETSQRRTIIPWPLKLAYTAFTAVLTVYYWREYGPTNFLYFCDIALFLAVLAVWTEKPIYASMAAVGITIPQLLWQIDFLGAFAGVRVIGMTEYMFDDSISLIARGLSFFHFWLPILLLYLVWRLGYDRRALIGWTIIAWGAMLIAYFVLPGPGDPLAFPNQPHNVNYVFGPAPETAQTWMPGWAWLSCLMLGLPALFYLPTHAALAYWDKQTRRVDVTPESGNRMPSAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INM1</accession>
    <name>A0A518INM1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_06170</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010869">
        <property type="entry name" value="DUF1501"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07394">
        <property type="entry name" value="DUF1501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="491" mass="53632" checksum="03C981A6DAEEA8ED" modified="2019-10-16" version="1">MTLKTQNAACGRTERRQFLSDFGLGFTGLALGAMMHRDAAGSTATVAARGLPHFAPRAKSVIWFFMNGGTSHLESFDPKPALNQHAGKTIDESPLGQAIVDSPFYRKNVVDFGGKPRAMMSQIYPMQVGYGPRGESGIEVSDWWPHVGDCIDDIALVRSMWTTDNDHAAQLQFHTGRHIFDGFFPSIGSWVHYGLGSLNDNLPQFIVMGNPPGDCCGGVGAHDGSYLGPQHAGVQMVSDPNRPLAFGTPGSGTRVAQQRDQLDLLDDLHRMTAAARPDDEALRARIKAYELAFRMQMSVPEIVDLNRETKQTQAMYGLDVKQTQQVGRHALTARRLVEQGVRFVQIYDGGGGGGGWDAHTKLKENHARNCARVDKPIAGLLKDLKQRGLLEETLVVWATEFGRTPGAEKSDGRDHHPYGFSVWMAGGGLKGGVAHGATDELGFHAVEDRHYVTDIHATVLHQLGLDPRKLSLPSQKRLEIDYGNPIEAIIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INS6</accession>
    <name>A0A518INS6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nudix hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_07040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="1">
        <location>
            <begin position="13"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="148" mass="16841" checksum="B61D0BBA19802B66" modified="2019-10-16" version="1">MDTNKDRADRRQRTGMGVVGVILREDRFLLIRRSKTVTAPGFVCFAGGGVEAGESEQDALVREMQEELAIDIVPTQRIWESVTRWGTELGWWLIEAAHDLDPVPNPAEVEEIFWLKRSEITPRRDLLGSMPDFLGAWQQGAFKLPIDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INU5</accession>
    <name>A0A518INU5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glutamate-1-semialdehyde 2,1-aminomutase 1</fullName>
            <ecNumber evidence="7">5.4.3.8</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">hemL1</name>
        <name evidence="7" type="ORF">Mal33_07310</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="5.4.3.8" evidence="7"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042286">
        <property type="term" value="F:glutamate-1-semialdehyde 2,1-aminomutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001031">
        <property type="entry name" value="Thioesterase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00975">
        <property type="entry name" value="Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="1 4" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
            <begin position="9"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="87"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="222"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="89"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="222"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4">
        <location>
            <position position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV54766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1073" mass="116943" checksum="A337E3A4BD0D9B57" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP21</accession>
    <name>A0A518IP21_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NanoRNase/pAp phosphatase</fullName>
            <ecNumber evidence="3">3.1.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_08180</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.-.-" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001667">
        <property type="entry name" value="DDH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038763">
        <property type="entry name" value="DHH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003156">
        <property type="entry name" value="DHHA1_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01368">
        <property type="entry name" value="DHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02272">
        <property type="entry name" value="DHHA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64182">
        <property type="entry name" value="SSF64182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DHH" evidence="1">
        <location>
            <begin position="19"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="domain" description="DHHA1" evidence="2">
        <location>
            <begin position="260"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="326" mass="35501" checksum="14B9226D90537305" modified="2019-10-16" version="1">MPVNWKKFKDTIAHYENFVLTSHIRPDCDALGSELGMAEVLRAVGKKVRIINAHDTPPGLQFLDPAGNIEVLRRHVEAEDIETDCIMVLDTSAWAQLGAMAQVVEETRADKLIVDHHLGEDDMGALLFKDTSAEATGHLVVQAADALGVPLTKKMAMPLYAAIATDTGWFRFSSTSADTYRCIARLVDAGASPTEIYGDLYERDTLGRVKLRGRILSRTTAELGGRLVYTWVLAEDFEKTGALPSDTEDAINLTLAIAGTDAAVIMIEQLKGGFKLSFRSRCEMNCNDVARVFGGGGHKAAAGAFIEGNIETVKEKVLPVVMEMMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPA2</accession>
    <name>A0A518IPA2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Mal33_09010</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the glycosyltransferase 87 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016758">
        <property type="term" value="F:hexosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018584">
        <property type="entry name" value="GT87"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09594">
        <property type="entry name" value="GT87"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="25"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="121"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="172"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="197"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="229"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="301"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="327"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="352"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="379"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="411"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV54935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="444" mass="48719" checksum="3A68C0D11C1D8286" modified="2019-10-16" version="1">MKESTTDNEPRDDAADSSTQRHRQIVSWLAAACFLIGVVLTAGRIVLAYQTPGPFDPSRQGYCDFHNGVYFPALAFREGVSPYSSAYVQQYPVERSIPFYSPLVLALHAPLTWLPLAVAEVVYFIVSLGMLLGIAWLSVRWTTGSAGAGWRWDWFWIVASSLVFTRGGQQTLFTGYFTFELILGALLAVHYGKTHPWRSVLGLVVISCKPTFVLPIAGLMLFRGNIKAVAFAGVISLVLAVACFGWLIQSGSAAELMSDIGTSQDVHRSDDYELPANTWTRIDVLAIVAKWTDWVPGDATHLVWMIGLLLPAAIVLMVYHRHNRDDGAATGLSGAIVLLTSLVAIFHQVYDVMILTPAIVAILIALRPAWDALSWRMRMFLAISMLIPALNYASSLMVLNRFQIDGFAKDVVTSLNAISLLIACVVLLVLAWNRCGGRANRASV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPD6</accession>
    <name>A0A518IPD6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_09330</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009599">
        <property type="entry name" value="DUF1207"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06727">
        <property type="entry name" value="DUF1207"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="335" mass="37401" checksum="8BB43B7B5178843E" modified="2019-10-16" version="1">MAVLCCDAAIAQRVASLTPTTSQSLPTPGAITAALNDSQSLSFDPYQTSPPQTQVAGLPPLPLAPLPFAPQTLQPLGMSPQSTVWQWQLLPKDSIYPVYLADEKASRLAGRFTRPEGDNLLLDGTLGGRFGLFRFGDRSNGPFRHGMQLDIEGSAQVRLDMEEEADVRSVDFRAGVPLSFGFGRWQTRVGYYHLSSHTGDEFLLKNPDHDRLNFSRDVLFAGAAFWITERLRTYGEVGWAFYSDVSEQWEFMFGIEFMPTAPTGWRGAPFAAAHAHLREELDYGGSLTLQAGWAWRGRDGALLRLGVDFYEGKSQQWSFYDSYEPLIGFGLWYDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPD8</accession>
    <name>A0A518IPD8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Prenyltransferase and squalene oxidase repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Mal33_09000</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein prenyltransferase subunit beta family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008318">
        <property type="term" value="F:protein prenyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001330">
        <property type="entry name" value="PFTB_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045089">
        <property type="entry name" value="PGGT1B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008930">
        <property type="entry name" value="Terpenoid_cyclase/PrenylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11774">
        <property type="entry name" value="PTHR11774"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00432">
        <property type="entry name" value="Prenyltrans"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48239">
        <property type="entry name" value="SSF48239"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0637">Prenyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV54934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="306" mass="33344" checksum="46DE00715D4A01C2" modified="2019-10-16" version="1">MTYLEALTIRLAQGAAELPEAMRQRQGDWLLAQQRPDGGFAGREGGSDLYYTAFALRSLMILGLLDGEPADRAAEFLKQRLQGREAIIDLISLIMAAKMLEISSGIDVMQSANGGWQDAIAELLETLRREDGGYAKSPEGRAGSTYQTFLTLLCYELIERSPPEPRQIEAFIRGQAQVEGGFLEIRVGKRAGVNPTAAAIGALRVLQRLDEPTQQLTTEFLAEMQINDGGMTANTRIPIADLLSTCTAIVTLTDLQSLDQIDRAAATRYVHSMERPGGGFAGFEMDPAEDVEYTFYGLAACSLLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPH7</accession>
    <name>A0A518IPH7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_09520</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="134" mass="14396" checksum="D27B303EF68E535B" modified="2019-10-16" version="1">MPKFRKVPACLADVVHQVISDLDLEERFRVEVDIPNNIPLPAPVRPLAEIVSALAEQATASMEAGGEVAFIGWESPDACELEIADSGRGLLERPCDLPAAMQMTGAELSWQNCPQGGAAVTVRFAKQQISRQAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPK8</accession>
    <name>A0A518IPK8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_09990</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011453">
        <property type="entry name" value="DUF1559"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07596">
        <property type="entry name" value="SBP_bac_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="354" mass="37716" checksum="017A93DEF3DF0C34" modified="2019-10-16" version="1" precursor="true">MFTEPCRIRRTNGRLGFTLVELLVVIAIIGILVGLLLPAVQAAREAARRMQCSNNLKQLGLAALNHESTYGLVPASLIVELGSAPGASGQPGYPYPGIVHSWAPQFLPYIEQNALYERYDLKYPWFSSPSSVPGTPDNLAVTQQVVSSFICPSTPGGSERRCSGKFNFSVDFPFTDMAVTDYATNSSINPGSITFFGYPSGLSQSDLFSAMKPSLKGPGITPILGESNSQANKIGFVDGTSNTILLCESAGRPDFYINGKSQGVTRSDGGWAHHENDYGLDGAISGTDSSPGNCVINCHNNNETYSFHPGGANHGFSDGSVRFISETTSAQVYAALITANGSGYTDAEVSPWQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPL9</accession>
    <name>A0A518IPL9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Flagellar motor switch protein FliG</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">fliG_1</name>
        <name evidence="14" type="ORF">Mal33_10070</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Bacterial flagellum basal body</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the FliG family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009425">
        <property type="term" value="C:bacterial-type flagellum basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003774">
        <property type="term" value="F:cytoskeletal motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000090">
        <property type="entry name" value="Flg_Motor_Flig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023087">
        <property type="entry name" value="Flg_Motor_Flig_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011002">
        <property type="entry name" value="FliG_a-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032779">
        <property type="entry name" value="FliG_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028263">
        <property type="entry name" value="FliG_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30534">
        <property type="entry name" value="PTHR30534"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01706">
        <property type="entry name" value="FliG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14841">
        <property type="entry name" value="FliG_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14842">
        <property type="entry name" value="FliG_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00954">
        <property type="entry name" value="FLGMOTORFLIG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48029">
        <property type="entry name" value="SSF48029"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="14" id="KW-0966">Cell projection</keyword>
    <keyword evidence="6" id="KW-0145">Chemotaxis</keyword>
    <keyword evidence="14" id="KW-0969">Cilium</keyword>
    <keyword evidence="7" id="KW-0283">Flagellar rotation</keyword>
    <keyword evidence="14" id="KW-0282">Flagellum</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FliG_N" evidence="13">
        <location>
            <begin position="6"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="domain" description="FliG_M" evidence="12">
        <location>
            <begin position="115"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="FliG_C" evidence="11">
        <location>
            <begin position="270"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="63"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="222"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF14841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF14842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="QDV55039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="373" mass="40436" checksum="32BF3B3E16E75560" modified="2019-10-16" version="1">MDQGSLRRVAVLLDSLDQVTASQLLAKMPPSRAAQVRYAISQLSGVDPLERKMAIADFMQKSQNATTPRPTPVASEPAAAAAPATATSSPAENTAEEEAESRDPLHFLNEMPIRALVSALSDEHPQTVAIVLASMQPSVAAQLLSDLPTSVCKSAIQRLAAITEIPSQALQEISEHLQSLMKKVTPAEPQAGSRSLASILTHLDLDQRKQILSELPDLAASLPPEPVAPVESAPPEPPQQLDEWDSGAIESAEVVDELHLDLDSEPTPIDFAPIERLPADALRRVLLEVEVDTAILSLCGMDPRVVQRLLTILPRNQRREVQDLMRKIDNVELRQIDASQRELYDAAMQLHDAGKLPELHLPASAPSRMSFAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPQ8</accession>
    <name>A0A518IPQ8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_10180</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="50" mass="5776" checksum="56EB7951D72A3CF6" modified="2019-10-16" version="1">MLTAKQAVTNLVSSFVTRQASRSDSRRDFRNPPWPQSLDDFRYAKSTETL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPT2</accession>
    <name>A0A518IPT2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_10510</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007742">
        <property type="entry name" value="NosD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006626">
        <property type="entry name" value="PbH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05048">
        <property type="entry name" value="NosD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00710">
        <property type="entry name" value="PbH1"/>
        <property type="match status" value="15"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021900691" evidence="2">
        <location>
            <begin position="31"/>
            <end position="1002"/>
        </location>
    </feature>
    <feature type="domain" description="NosD" evidence="3">
        <location>
            <begin position="622"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="domain" description="NosD" evidence="3">
        <location>
            <begin position="855"/>
            <end position="965"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="975"/>
            <end position="1002"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV55082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1002" mass="103440" checksum="814B0928ACDB92EE" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPX0</accession>
    <name>A0A518IPX0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_11100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="487"/>
            <end position="530"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="530" mass="58023" checksum="0B7CA6DB72E3E500" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPX6</accession>
    <name>A0A518IPX6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Purine nucleoside phosphorylase</fullName>
            <ecNumber evidence="6">2.4.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Inosine-guanosine phosphorylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">punA_2</name>
        <name evidence="8" type="ORF">Mal33_11060</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 6">Purine metabolism; purine nucleoside salvage.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homotrimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the PNP/MTAP phosphorylase family.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.1" evidence="6"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00606"/>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004731">
        <property type="term" value="F:purine-nucleoside phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009116">
        <property type="term" value="P:nucleoside metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09009">
        <property type="entry name" value="PNP-EcPNPII_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000845">
        <property type="entry name" value="Nucleoside_phosphorylase_d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035994">
        <property type="entry name" value="Nucleoside_phosphorylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011270">
        <property type="entry name" value="Pur_Nuc_Pase_Ino/Guo-sp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011268">
        <property type="entry name" value="Purine_phosphorylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018099">
        <property type="entry name" value="Purine_phosphorylase-2_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11904">
        <property type="entry name" value="PTHR11904"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01048">
        <property type="entry name" value="PNP_UDP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000477">
        <property type="entry name" value="PurNPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53167">
        <property type="entry name" value="SSF53167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01700">
        <property type="entry name" value="PNPH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01697">
        <property type="entry name" value="PNPH-PUNA-XAPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01240">
        <property type="entry name" value="PNP_MTAP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 8" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PNP_UDP_1" evidence="7">
        <location>
            <begin position="25"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR000477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV55137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="279" mass="30185" checksum="29150072F96D1608" modified="2019-10-16" version="1">MLDLYDKIQESTAAIKAAWGTTPRAGIILGTGLGGLVDEIEIEASLDYSEIPHFPTSTATSHRGRLVCGKLQGVPVVAMEGRFHMYEGYPLKQITLPVRVMKALGAELLVVSNACGGLNPYFQSGDIMVIEDQINLMGDNPLIGINDDRLGPRFPDMCEPYSQRLVDTALEIARRENIRAHKGVFVAVAGPNLETRAEYRFLRTIGADVVGMSTVPEVIVAVHCGLKVVGFSVITDMCLPDALQPAVVEEIIAIANAAEPNLRTLVRQSVADFANDRLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQ19</accession>
    <name>A0A518IQ19_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_11580</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="391" mass="43580" checksum="469FCE239BC15DDF" modified="2019-10-16" version="1">MPFLGGSLAFERFDVSGFDAPQFIDEHIEILDSHRAGQTQTSSTENIHVGFLGGSHLFDPDFDISKNVINDALHCGVRIDTNQIPAAIRNAWLQMELAALAKDNSSGVPTKAQRKEAKEAVEQRCDVEAATGKYRKMQQFPILWDQRNSMLYFGGSTGTASGHCADLLERTFEIELRHVSAGTIAMQWGRDNKQLADVEDLVPACFVPNHHHGDIAWTSEHSQAPDFLGNEFLLWLWWTLENETDTFELPDESEVTVMLNKTLTLECPAGESGKEVISAEAPTRLPEAMQAVRCGKLPRKTGMTVVRDGQQFDLVLQAETFAISGAKIHVDEDMEFGVEDRIDAIRALSETIDLMFHVFCARRVSSAWSKDLGEIVNWLEVSDQRDQKSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQ67</accession>
    <name>A0A518IQ67_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_12110</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021954012" evidence="2">
        <location>
            <begin position="20"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="113" mass="11498" checksum="51F6822528C6A056" modified="2019-10-16" version="1" precursor="true">MLRVSLLCASLMMMFLVVGCEDATKMKDDASTATEEAVGDMADHAEEGADKAGDAAADTMEAAKATAGDAVEAVKEKTGEAVEAVKEAAGDATDAAKKKVNEAADAVKKATDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQU0</accession>
    <name>A0A518IQU0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Prenyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_14290</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016765">
        <property type="term" value="F:transferase activity, transferring alkyl or aryl (other than methyl) groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000537">
        <property type="entry name" value="UbiA_prenyltransferase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01040">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="85"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="139"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="193"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="223"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="254"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV55455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="279" mass="31810" checksum="5C428537C7F9DD95" modified="2019-10-16" version="1">MLEIIKIARPGFWPTHVWFYLLPFAGRDMFGSIPFWLGCFYVSFPLGLLLYGWNDLGDYVSDRCNPRKDSWLFGGRPDAAMRRRLPWIIAAVQVPFLIAFVIIGGWWMLLWFAAVLLTNATYNTLGFKRLPVLDLLNQIGYLLIFLLGSWLCGVPQLNAATMVFSALFAMQSHLFGQLMDIEEDRIAERHNTAITLGAVPSKWLLVGIMLVEVAISWTYFQSPIVAGFMFAGAIFFSLDALAGPKQYPPLFTKLFFIAWNLIVIATMHFVWRYGVFLVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQW1</accession>
    <name>A0A518IQW1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF1080 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_14240</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010496">
        <property type="entry name" value="3-keto-disaccharide_hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06439">
        <property type="entry name" value="DUF1080"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022236140" description="DUF1080 domain-containing protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1080" evidence="2">
        <location>
            <begin position="28"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="229" mass="25911" checksum="5D78B6A4F4C3286A" modified="2019-10-16" version="1" precursor="true">MQATTNIAALLLSAFLISGAAIGQDDDQWTDLFNGEDTSGWNNPYEWGEVNVVDGEIHLTASKKFFLVTDKKYGDFVFEGEVMIPEGQANSGFMFRCHSEKNKVYGYQAECDGSDRRWSGGLYDESRRGWIWPSIKGRTKEAKFLEHAEESQAYFKKPEVAGALDRNGWNKYRITCQGDSLKIEVNGVVTTEIEDDTDASGFIAIQHHGEKGQTYRFRNLRIKELKPQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IR33</accession>
    <name>A0A518IR33_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphocarrier protein NPr</fullName>
            <ecNumber evidence="2">2.7.11.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ptsO</name>
        <name evidence="2" type="ORF">Mal33_15190</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.11.-" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00367">
        <property type="entry name" value="PTS-HPr_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1340.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000032">
        <property type="entry name" value="HPr-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035895">
        <property type="entry name" value="HPr-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00381">
        <property type="entry name" value="PTS-HPr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00107">
        <property type="entry name" value="PHOSPHOCPHPR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55594">
        <property type="entry name" value="SSF55594"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01003">
        <property type="entry name" value="PTS_HPr_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51350">
        <property type="entry name" value="PTS_HPR_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HPr" evidence="1">
        <location>
            <begin position="8"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="98" mass="10445" checksum="8900F2E41C631609" modified="2019-10-16" version="1">MHAMSNPSCQQIVVVKNEKGLHLRPAELMARLAMQYEATVMVTKDDQSADCKNMLSVLTLGAVQGTQLGLSAEGPDAAEALSAVAELFEAGFHELDAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IR57</accession>
    <name>A0A518IR57_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">WD domain, G-beta repeat</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_15530</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_repeat"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021937785" evidence="2">
        <location>
            <begin position="32"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="445" mass="47431" checksum="AE113A8F402BEB20" modified="2019-10-16" version="1" precursor="true">MLDPFAKTIRTNWFASLSLAAVLSFASPLFADDEPTKPAAKEQPPAAEAKPEAKPEAKPEAKPEAKPEPKPEPKPEPKPEPKPEPKPEPKPEPKPEPKPEPKPEPKPEPKPEPKPEPKPEPKPEPKPEPKPEPKPEPKPEAKSEATWPHRWVTAVSTNAGRVCAAAADGLLLREANVVAVNPADLAGSETLYTHPASVWAVAVAPDGASVASTDYKGNLGIYRFDSEQLTMKETVFERWTRALAFAPDGSVLVAANEAGKVFVYDVAKGEVIQSVELGGQQIYSLAFSADGKLLAAGDGAGSVHLLKLAGLETVKKVACGEAPIWAVCFSANDKQMFAGGSDRKLRRIEVDGEAEPTVLGQASDWITAIDCNPGASQIAVGSMDGTMFTSDGNNFEKIGKVPSGIWSVAFADGKLLAATRKHMIASFVPSWKSGYTAPDIAELKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRW3</accession>
    <name>A0A518IRW3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Patatin-like phospholipase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_18170</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="1 2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNPLA" evidence="3">
        <location>
            <begin position="6"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="DGA/G" evidence="2">
        <location>
            <begin position="210"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="41"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV55838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="375" mass="41856" checksum="9D200ABD74DB0594" modified="2019-10-16" version="1">MKIALAFSGGGVRATVFHLGVLARLARQDLLSSVKIVSSVSGGSLAAGLVFATAGNRWPSSEQYLHDVVPRCLSLLTTRNLQRTFVMKSLMQPWRLMSGRASVLGDVLESTWGLKGSLADLPIAPRWLINATCYQTGKNWRFQRDLMGDYQTKYVPDPDFRLSHALAASAAVPGLIGPLLVRSKKYQWSEFCEDDWKAIRPKYKHLHLWDGGVYDNLGVEPLFKPGEGLREGTDYLIVCDASRPLASETRQSRWRPGFLQASLRLVDVATDQVRSLRARMLMEHFKQNPGTGAYLRLGLATKSVYARSPTPGKPALSDDEVQRVAQIETTLRQLSHNEFSLLFRHGFEVADAMLSTYGQESLRHVPRNRVLFKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRY3</accession>
    <name>A0A518IRY3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Na(+)/H(+) antiporter subunit G</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">mrpG_1</name>
        <name evidence="2" type="ORF">Mal33_18380</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005451">
        <property type="term" value="F:monovalent cation:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098662">
        <property type="term" value="P:inorganic cation transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005133">
        <property type="entry name" value="PhaG_MnhG_YufB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34703">
        <property type="entry name" value="PTHR34703"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03334">
        <property type="entry name" value="PhaG_MnhG_YufB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01300">
        <property type="entry name" value="CPA3_mnhG_phaG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="111" mass="11584" checksum="CB5E2E60125ED71B" modified="2019-10-16" version="1">MIALDILSWALMLIGAFFSIVGGIGIVRLPEFFSRLHGAGITDTMGAGAILLGLVFQVGLSLAAVKLIMILFFLLVTSPSSCHALARSAVTHGLKPVLDSSRRDGSSGTEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRZ3</accession>
    <name>A0A518IRZ3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Indole-3-pyruvate decarboxylase</fullName>
            <ecNumber evidence="10">4.1.1.74</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ipdC</name>
        <name evidence="10" type="ORF">Mal33_18470</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="5">Binds 1 Mg(2+) per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the TPP enzyme family.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.74" evidence="10"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047434">
        <property type="term" value="F:indolepyruvate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012000">
        <property type="entry name" value="Thiamin_PyroP_enz_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012001">
        <property type="entry name" value="Thiamin_PyroP_enz_TPP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000399">
        <property type="entry name" value="TPP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012110">
        <property type="entry name" value="TPP_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011766">
        <property type="entry name" value="TPP_enzyme-bd_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43452">
        <property type="entry name" value="PTHR43452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02775">
        <property type="entry name" value="TPP_enzyme_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00205">
        <property type="entry name" value="TPP_enzyme_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02776">
        <property type="entry name" value="TPP_enzyme_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036565">
        <property type="entry name" value="Pyruvt_ip_decrb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00187">
        <property type="entry name" value="TPP_ENZYMES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="4 10" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="TPP_enzyme_N" evidence="9">
        <location>
            <begin position="23"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="domain" description="TPP_enzyme_M" evidence="7">
        <location>
            <begin position="213"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="domain" description="TPP_enzyme_C" evidence="8">
        <location>
            <begin position="399"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="452"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="479"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="481"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR036565-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV55868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="568" mass="62547" checksum="F3471FF8EF59E53A" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IS26</accession>
    <name>A0A518IS26_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Calx-beta domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Mal33_18760</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007154">
        <property type="term" value="P:cell communication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2030">
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006644">
        <property type="entry name" value="Cadg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015919">
        <property type="entry name" value="Cadherin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038081">
        <property type="entry name" value="CalX-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003644">
        <property type="entry name" value="Calx_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002105">
        <property type="entry name" value="Dockerin_1_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036439">
        <property type="entry name" value="Dockerin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043710">
        <property type="entry name" value="DUF5650"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006626">
        <property type="entry name" value="PbH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040853">
        <property type="entry name" value="RapA2_cadherin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17803">
        <property type="entry name" value="Cadherin_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03160">
        <property type="entry name" value="Calx-beta"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00404">
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</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
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        <submittedName>
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
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                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
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                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
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                <person name="Mascher T."/>
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                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
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    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
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                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
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                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
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                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
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        <text evidence="1">Belongs to the UPF0677 family.</text>
    </comment>
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        <source>
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</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
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    <name>A0A518ISQ9_9BACT</name>
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        <submittedName>
            <fullName evidence="6">Planctomycete cytochrome C</fullName>
        </submittedName>
    </protein>
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        <name evidence="6" type="ORF">Mal33_20980</name>
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    <organism evidence="6 7">
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        <dbReference type="NCBI Taxonomy" id="2527990"/>
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            <taxon>Planctomycetia</taxon>
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            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
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                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
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                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
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    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="DUF1549"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="SSF46626"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
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    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022163669" evidence="2">
        <location>
            <begin position="25"/>
            <end position="954"/>
        </location>
    </feature>
    <feature type="domain" description="PSCyt1" evidence="5">
        <location>
            <begin position="42"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="PSCyt2" evidence="3">
        <location>
            <begin position="148"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="domain" description="PSD1" evidence="4">
        <location>
            <begin position="667"/>
            <end position="924"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="373"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV56119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="954" mass="107652" checksum="033DEA7F01860CE7" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISY5</accession>
    <name>A0A518ISY5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_21710</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="401" mass="42724" checksum="7811ED71EFC8CDCB" modified="2019-10-16" version="1">MVCIPCDSLPSRAVMAMVSAQAFGRSSSLCPLVMMMVNLRSVLLSIAWFSAAILPAVCAADSFDDQLRSVCRVVGTELPLRVVAQRIGDAHGINVWIDRRVDPSTPVSLSAAAGSLQQTLEAIAAKSQLEVGYASPVVILAPQGVAIDTATRILKLRSEMKQLPISAATRLLEPQDLAWDRLSTPAEIAQQIAAAWQVSVVGESLPHDLWDRCKLRGVDAADALVLLAAGFDLAPNYDPQQATFGFDRIEKSAGVALEYPSTKVAASMARELRKIDPDVKLENRGALIRVTGNSAVHHRIRSDRSAAKPKQNGGLADVAPGMRRFTLRIPGMKPAASILQAVCNASGFTLDTSAASSENLKRPVGLEVEDQLATAIIESICTQAGLTVRFDATTAVVADRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IT15</accession>
    <name>A0A518IT15_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_22200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="137" mass="15035" checksum="8ADC05A92F2D0CC1" modified="2019-10-16" version="1">MQTSCVRSGQVEVGIIAHQGKEFSAIGASVVGSNLTAYTRLKHSDTQLTSWCGQTILACRSEVVQRYADNSLAIMFRLTGNQFIVGYALADDGMLFRGELLSKSDEDDARYLARQLADDFAQLDADDEEAFALSEEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IT33</accession>
    <name>A0A518IT33_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_22230</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="91" mass="9863" checksum="0A8E025F84CE72A8" modified="2019-10-16" version="1">MKARELGIGVNGEYVLFYERSDTPTKPKVTPASKADHTGLLESLQALGLSGLTTKQVGEAVEACYPKGTNSEDENDILRTVFRHLKRSGIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IT75</accession>
    <name>A0A518IT75_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF4268 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_22710</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025364">
        <property type="entry name" value="DUF4268"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14088">
        <property type="entry name" value="DUF4268"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4268" evidence="1">
        <location>
            <begin position="228"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="378" mass="43490" checksum="5F33E8E1F08490A0" modified="2019-10-16" version="1">MPLFQLSKTELAEIATASFESLGYKEREDLQRLLRERIEIIVPDGFVVAEEFADWDESKRRIDLLVLDRNANLVIVELKRTEDGGHSELQALRYAAMISTITFDQVVEAHRNFLARLGIREDPQTRILKFLAWNEPDDDRFGQDVRVVLASADFSKELTTTVLWLNDQGLDIRCVRMRPYAHDGKVILDVQQLLPLPETQEYQVRVREKLSSEKSARQGQTERQRRNLAFWAGLLKKAGERSTLHQSISPSKDNWATVSSRGLGMSYVLARGGGRVELYINRTSQAENKSIYDELYLQRAQIEAEFGDTLNWERLDGKLSSRVFYVVPSTGTEEEEGTWDQLQTDLIDHMLKLEAVLGSRIQKYRDGENFVVRQDEHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IT88</accession>
    <name>A0A518IT88_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 11">Adenylosuccinate lyase</fullName>
            <shortName evidence="11">ASL</shortName>
            <ecNumber evidence="4 11">4.3.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 11">Adenylosuccinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">purB</name>
        <name evidence="14" type="ORF">Mal33_22800</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>(2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate = 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + fumarate</text>
            <dbReference type="Rhea" id="RHEA:23920"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:58443"/>
            <dbReference type="ChEBI" id="CHEBI:58475"/>
            <dbReference type="EC" id="4.3.2.2"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:23921"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>N(6)-(1,2-dicarboxyethyl)-AMP = AMP + fumarate</text>
            <dbReference type="Rhea" id="RHEA:16853"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:57567"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="4.3.2.2"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:16854"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Purine metabolism; AMP biosynthesis via de novo pathway; AMP from IMP: step 2/2.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 11">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.3.2.2" evidence="4 11"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00132"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00075">
        <property type="reaction ID" value="UER00336"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070626">
        <property type="term" value="F:(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido) succinate lyase (fumarate-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004018">
        <property type="term" value="F:N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044208">
        <property type="term" value="P:'de novo' AMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020557">
        <property type="entry name" value="Fumarate_lyase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000362">
        <property type="entry name" value="Fumarate_lyase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022761">
        <property type="entry name" value="Fumarate_lyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004769">
        <property type="entry name" value="Pur_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013539">
        <property type="entry name" value="PurB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08328">
        <property type="entry name" value="ASL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00206">
        <property type="entry name" value="Lyase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00149">
        <property type="entry name" value="FUMRATELYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="SSF48557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00928">
        <property type="entry name" value="purB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00163">
        <property type="entry name" value="FUMARATE_LYASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 14" id="KW-0456">Lyase</keyword>
    <keyword evidence="6 11" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lyase_1" evidence="12">
        <location>
            <begin position="14"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="domain" description="ASL_C" evidence="13">
        <location>
            <begin position="330"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF08328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="QDV56298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="454" mass="50060" checksum="8E72C06D506BA685" modified="2019-10-16" version="1">MELSELTAISPIDGRYASKTSELREAFSEYGLIQCRVEVEVQWLLALASQSQITEVPQLSSEAAALLKGIVDNFSLADAEAVKSIEATTNHDVKAVEYFIKQRFEGNQELTAISEFVHFACTSEDINNLSHALMLRRGLDVLLPVMQKVASDLRDKAVVFAEVPMLSRTHGQTASPTTVGKEFANVVARLERQLAQLQAIPLLGKINGAVGNYNAHLSAYPDVDWADHARAFVESLGLHWNPYTTQIEPHDYMAELFDAIARFNTIVIDLDRDLWGYISLGYFKQKTIAGEVGSSTMPHKVNPIDFENSEGNLGLANAVLSHLSAKLPISRWQRDLTDSTVLRNTGVGMAYSMIAYKSTLKGLGKLELNAARLEQDLNSAWEVLAEPIQTVMRRYGIESPYEKLKALTRGQAVTAETFAAFIETLELPAEAKANLLQLTPSTYLGTAVQQAKNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITA4</accession>
    <name>A0A518ITA4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nucleoid-associated protein Mal33_22930</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_22930</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Nucleoid</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the YbaB/EbfC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043590">
        <property type="term" value="C:bacterial nucleoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1310.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00274">
        <property type="entry name" value="DNA_YbaB_EbfC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036894">
        <property type="entry name" value="YbaB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004401">
        <property type="entry name" value="YbaB/EbfC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33449">
        <property type="entry name" value="PTHR33449"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02575">
        <property type="entry name" value="YbaB_DNA_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004555">
        <property type="entry name" value="UCP004555"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82607">
        <property type="entry name" value="SSF82607"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00103">
        <property type="entry name" value="DNA_YbaB_EbfC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="121" mass="12550" checksum="55C59AE60BF4B9ED" modified="2019-10-16" version="1">MFKGLSDIASLMQQAQKLPAKMEELNRQLQAERVTGSAGGGMVTVEMNGTGEVTAVRIEQELIDQGDREMIEDLLPAAINEANGKAKAKQAESMQGLTGGINLPGMEAALSKFTGGGGGAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITB8</accession>
    <name>A0A518ITB8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_23100</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051304">
        <property type="term" value="P:chromosome separation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005234">
        <property type="entry name" value="ScpB_csome_segregation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34298">
        <property type="entry name" value="PTHR34298"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04079">
        <property type="entry name" value="SMC_ScpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0132">Cell division</keyword>
    <keyword evidence="2" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="22"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV56328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="381" mass="42120" checksum="1B6C16D3E5CCF437" modified="2019-10-16" version="1">MDDDNTADEDQEGKAKVDDELVDELGESEEDEAEDEAEDEAEDEAEDEAEDEAEDEAEDEAEDEAEDEAEDEAEDEAEDEAEDEAEDEAEDEAEDEADDEADDEADDEADDEADDEAEDEAEDEAEDEAEDEAEDEAEDEAEDEAEDEAEDDFSLDDLGAAYAEAMVEAGLMPEPPPAEEADTEAVEEDAAAEIDPIDEQLIEPPTPEGIVEAALFIGHPENKPLTAKELARVMRDVSPKEVESIIESLNAIYREDGHAMRIDKEQGGYRMLLSPEVDAVRRVFYGKVREARLSQVALEILALVAYQPGISAPDLSNQRGRDCGPLLNQLVRRRLLDVTREKAEGEGRAVPKYYPTQRFLNLFGLGSLEDLPQVDEDVLPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITJ0</accession>
    <name>A0A518ITJ0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_23910</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
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    </dbReference>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="153" mass="17305" checksum="78DCA38A110A38A7" modified="2019-10-16" version="1">MTFNKEDAVARKQQQIKVGLNLEIGPPPKYQWSAWVLDVANSEIRNTFAKPAVEHLILQVQELAREPSPSSSDILRIEKVEDFFELKDKGGVLGNVNARLFFGIDKRERAIVIIGGMKKQNNGKTPAGDRVRMRRRWRNYLDGTYGKPGGGVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITT6</accession>
    <name>A0A518ITT6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_24890</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="108" mass="11734" checksum="159AC9E5464A5522" modified="2019-10-16" version="1">MSPNQQLIAAVVVGLIVLLAIAVVVVLVIRRNRKRCGCAPGCETPTPFTSLRNVRPTSNSFAVDCEEAQAYIDMRAEAKARQHKLAVARSMRELADAQLAEEDAAEVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITW2</accession>
    <name>A0A518ITW2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Squalene--hopene cyclase</fullName>
            <ecNumber evidence="6">4.2.1.129</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">shc</name>
        <name evidence="6" type="ORF">Mal33_25260</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Secondary metabolite biosynthesis; hopanoid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the terpene synthase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.129" evidence="6"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00337"/>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005811">
        <property type="term" value="C:lipid droplet"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016866">
        <property type="term" value="F:intramolecular transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016104">
        <property type="term" value="P:triterpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001330">
        <property type="entry name" value="PFTB_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032696">
        <property type="entry name" value="SQ_cyclase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032697">
        <property type="entry name" value="SQ_cyclase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018333">
        <property type="entry name" value="Squalene_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008930">
        <property type="entry name" value="Terpenoid_cyclase/PrenylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11764">
        <property type="entry name" value="PTHR11764"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00432">
        <property type="entry name" value="Prenyltrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13243">
        <property type="entry name" value="SQHop_cyclase_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13249">
        <property type="entry name" value="SQHop_cyclase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48239">
        <property type="entry name" value="SSF48239"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="SQHop_cyclase_N" evidence="5">
        <location>
            <begin position="28"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="SQHop_cyclase_C" evidence="4">
        <location>
            <begin position="298"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="domain" description="SQHop_cyclase_C" evidence="4">
        <location>
            <begin position="463"/>
            <end position="641"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV56534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="649" mass="70893" checksum="6A0CAF329A9519D1" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUA1</accession>
    <name>A0A518IUA1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Helix-turn-helix domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_26720</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041657">
        <property type="entry name" value="HTH_17"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12728">
        <property type="entry name" value="HTH_17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_17" evidence="2">
        <location>
            <begin position="8"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="407"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="178"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="269"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="595" mass="60032" checksum="87ED4879BD228AC3" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUC4</accession>
    <name>A0A518IUC4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Molybdenum cofactor biosynthesis protein A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Mal33_26530</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024521">
        <property type="entry name" value="DUF3641"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026351">
        <property type="entry name" value="rSAM_SeCys"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43728">
        <property type="entry name" value="PTHR43728"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12345">
        <property type="entry name" value="DUF3641"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04167">
        <property type="entry name" value="rSAM_SeCys"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0349">Heme</keyword>
    <keyword evidence="3 5" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Cytochrome c" evidence="6">
        <location>
            <begin position="65"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV56660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="376" mass="41955" checksum="3A5D3C647AE41757" modified="2019-10-16" version="1">MPTRLNEVSVHQPSDPQRIHTMQLSLLRQKSELANAARQREVLEDEFTPPLPYFTEALSNNGLPRLTATGIEVLQINVGKLCNQTCTHCHVDAGPDRRESMSRATAEAIIDVLARHDIPTLDITGGAPEMNPNFRWLVEQATLLGRRVIDRCNLTILMANGYRDLPEFLAEHEVEVVASLPCYLEENCDSQRGDGVFKRSIDGLRRLNALGYGQPDSPRTLNLVYNPVGPSLPPSQAALEATYRSELKSRYDIVFTNLHTITNLPISRFLDDLLRSDQFDNYMQKLIESFNPVTVEGVMCRTMVSVDWQGHLFDCDFNQMLNIGLSPEQPRHISDFDFESLASRGIQTGRHCFGCTAGNGSSCQGAVVKIGTEKPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUD2</accession>
    <name>A0A518IUD2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_26900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011453">
        <property type="entry name" value="DUF1559"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07596">
        <property type="entry name" value="SBP_bac_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="335" mass="35908" checksum="62A2065E52851ECD" modified="2019-10-16" version="1">MFAKRRAFTLVELLVVIAIIGILVGLLLPAVQAAREAARRMQCGNNMKQLGLALHNYVDTYQKFPASSRGYGGCVGNAVNGEIKNASGLVALLPYIELQNVYDQFNHEEAFAVTSSGQRATGNVIGDPATNGNATIAELELDVFACPSDSNPIKGRLVGNHYGPAPGFSGAATNYDFIVAASPEFASCNSYATSNSTTKRMFGGDVNTRMAEVIDGLTNTFMVGETTRYHVNGAALAWSYRGWVMTGVDPYYTSAANGGINVWHQPWISPTWQSPPFTPIRGRARSWWVASASLHPGGCHFAMGDASVQFVSETIDKPTLLNLTVMSDGQVATLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUH1</accession>
    <name>A0A518IUH1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_27300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010775">
        <property type="entry name" value="DUF1365"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33973">
        <property type="entry name" value="PTHR33973"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07103">
        <property type="entry name" value="DUF1365"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="285" mass="33018" checksum="50DECC712DCD28C9" modified="2019-10-16" version="1">MNASAAIPSDASLISELEVESAAEVTSDLSPPARSSCLYFGTIRHRRFVPVGHQFCYSLFLAMIDLDEVNSLFRFPLFCSTSRFSLLRFRRSDYCGDPERPLADCIRELVQDQIGLTVTGPIRLLTHLRFFGLSFNPASFYFCYHADGRRLQAIVAEVTNTPWGERHCYVIPCDGDSRIHRHQCRKVFHVSPFMPMQMMYRWRISTPAQQLSVQIENFDEATQVFDATLQLKRQPFSYRRLVWAVVRFPLMTCQVVAAIYWQALRLWWKKVPFVPHPGRHREASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUV7</accession>
    <name>A0A518IUV7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_28690</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007432">
        <property type="entry name" value="DUF480"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38768">
        <property type="entry name" value="PTHR38768"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04337">
        <property type="entry name" value="DUF480"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="180"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="208"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="181"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="241" mass="26306" checksum="7DDC80FC3786D7D2" modified="2019-10-16" version="1">MDVDQESAAPKWKPLGTTERRVLGVLIEKAKTTPDNYPITLASLTAGCNQKSNRAPQMQLNDDDVDLSLDRLRSVGVAVEVQGSGRVPKYRHTAYDWFDVKGPEIAVLTELLLRGEQTAGELRTRASRMEPFQDLAALQPVLQMLLDKNLIVALTPPGRGQLFTHNLYPDADLAHLRKKITGDSSSPSPQPVAVASQPATPVPAAAAVAPANDELQSMRDEIARLSEEVAQLKQRLDILES</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVI8</accession>
    <name>A0A518IVI8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">3'-5' exoribonuclease YhaM</fullName>
            <ecNumber evidence="2">3.1.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">yhaM</name>
        <name evidence="2" type="ORF">Mal33_30980</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.-.-" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HDc" evidence="1">
        <location>
            <begin position="159"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="323" mass="36259" checksum="8FB04E6B7C62F485" modified="2019-10-16" version="1">MSERLFINQLSEQTQVDDVYRAADKQLRANRQGNKYILLKLADRTGTLTGMFWNAEDRDFERCQDSEYLHVKGRTQIYNGNMQMIVTGISPVDPSQVDPADFDMFDASASEQAFARLKELLGSVRNIHLRQLLDACLADEEFMTRFKQSPAAVTNHHAFPGGLLRHTVDLIELAQLIGPRYPQLDIDLLTTGAFLHDIGKTEELSSGGELTYTDRGQLVGHIVIGVQYLADRIAVVEAETKSPFPVQLKWHLEHLILSHHGLLEYGSPKVPLTREAIALHHLDNLDAKLAAATSIIDSDISGDKNWTNYNPSMGKKLWKSPIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVJ6</accession>
    <name>A0A518IVJ6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Septum site-determining protein MinD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">minD</name>
        <name evidence="3" type="ORF">Mal33_31120</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="6"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="411" mass="44653" checksum="727B09E4F4ED5520" modified="2019-10-16" version="1">MPNVLRLAVVDPNDKTREDLKAMLLGLDVVWLEAECSRYEFFPDVVTQTHPDIGVVSLDSDPERGIELLNTIRSTTPDCALLVVSSSTSGQLILQSMRAGAKEFLTLPLSGGDLSAALHRIGEQKFGASDSRNRNCEVIVVAGATGGVGATSVAVNMGCMLASREGNSVALMDLDLAVGDADVFLDSIPDYTLADVTQNIARLDFTLLKRSLTKHSSGLYLLPRPVELQDMSIINGDSIEKVITLLKASFTHLVIDLSKTYSEVDMAAMQMAAKIILVTQLDVPCLRNVVRLLLSFEQYEGLKEKVHVVVNRAGLESGPISIRKARETIGCDIYAQLPNDYRTMVEVRNNGVPLFEQDPKAAITLAMLGLVERLSGSSKETQEEESGEAVAVTESSGWLNFWPRGGKQKKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVK2</accession>
    <name>A0A518IVK2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SAF domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_31100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017592">
        <property type="entry name" value="Pilus_assmbl_Flp-typ_CpaB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031571">
        <property type="entry name" value="RcpC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013974">
        <property type="entry name" value="SAF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16976">
        <property type="entry name" value="RcpC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08666">
        <property type="entry name" value="SAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00858">
        <property type="entry name" value="SAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03177">
        <property type="entry name" value="pilus_cpaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAF" evidence="2">
        <location>
            <begin position="39"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="296"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="344" mass="37021" checksum="AD462914487D24B1" modified="2019-10-16" version="1">MRNKSVILLAIALGCGMIASVGISQVVMSGSEAQPTKMVEILVASMDIPSNAKIAADNIMLEKWPAGKTPEGAITDVTAIENKYAKQHIYAGEAILKQKVVDATERATVGIPPGHTVVTYSIGSDPGIANLIEPGDRINVIGFFEKSDIVPETTHRDVFRNVKIFAVDGRTSRETEEKAKRGPVSSILLLIKQEDERVWNWAKKVGSLQLTLGNPNEPVNPNTPNAAGIEFMKWLDDYAEERRLGQVETKPTEVLVEKPGGEIIKMLTPKGYRLFRWNKGTQTMELIQEHAPNDAQLGAGTSAADAGAVAPDASSGLPGAASVPQVDAGDSSTVNEAYRINRAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVU1</accession>
    <name>A0A518IVU1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_32060</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025048">
        <property type="entry name" value="DUF3987"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13148">
        <property type="entry name" value="DUF3987"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="621"/>
            <end position="647"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="647" mass="70141" checksum="EAB86A0286E10F06" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IW56</accession>
    <name>A0A518IW56_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_33110</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011444">
        <property type="entry name" value="DUF1549"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022655">
        <property type="entry name" value="DUF1553"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07583">
        <property type="entry name" value="PSCyt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07587">
        <property type="entry name" value="PSD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PSCyt2" evidence="1">
        <location>
            <begin position="89"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="domain" description="PSD1" evidence="2">
        <location>
            <begin position="362"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="588" mass="66308" checksum="D221E4DFCDC03DFC" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWA9</accession>
    <name>A0A518IWA9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transposase DDE domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_33780</name>
        <name evidence="4" type="ORF">Mal33_45750</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002559">
        <property type="entry name" value="Transposase_11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01609">
        <property type="entry name" value="DDE_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_1" evidence="2">
        <location>
            <begin position="132"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="422"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="436"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV58552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="463" mass="52685" checksum="E52F328054072851" modified="2019-10-16" version="1">MTTPENESDAEAPFCRAKALLSELLGLPQIQAAFEGQEASHAQRVYTQAPTLWLLVMQRLGGGLTLDQVVKDLIQNHSDILPENRRVTQGRLSENNSAYNKARQRLPVQRIEEFSHRVCDHLARRAEPAFLDHRVFILDGTTVTLPPTPGLKKAFPPARNQRGESVWPVACLMVAHEMQTGCALAPQIDPMYGPNNSSEPKQAKKIIDRLPENSIVLADSGFGIFSVAFHCQLRAKPFILRLTKQRYKAYIKNATLIEDAAGYRTYHLIWKPTAQERKKHPEFPVDAAVEAFIHQVDLENEQTLELVTSIEVDALSVGELYRRRYDVEFDIRDLKVTMDTENIRAKSVDTFMKELLGSVIAYNLVTQLRKQAAKLINVPPRRLSFSGVWTTFRYDLLYKECGTLQEWNHAFQRALVSASGRKLPNRKEPRSYPRLAHTRRQKSTKFQKSLRKSKRKGPAPPPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWB1</accession>
    <name>A0A518IWB1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_33390</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="79" mass="8890" checksum="6F34F2A7AEAA0ACD" modified="2019-10-16" version="1">MYDQREKALRDHEWRLAAAREEGEKIGEARGVVLGRIQILQSILSMTVSSEAALRDATTEQLIEIEADLQRIARARGQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWG0</accession>
    <name>A0A518IWG0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_34390</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="722" mass="80959" checksum="0F100E06A1D470A8" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWH1</accession>
    <name>A0A518IWH1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_34510</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021706519" evidence="2">
        <location>
            <begin position="23"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="157"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="159"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="253" mass="29082" checksum="776BCE01B2EB46B9" modified="2019-10-16" version="1" precursor="true">MRYLTATLAIALLSTATATARADHRLEAIAHDYHESVHILADYIAHDRHSSHYLSRYVSRLDDVSHDFYEALVHDPYRSRTRGLFDDVRSLHYRVRSLLGHGCRALPGAAAVWHDADRLYSRLSHAFSDNHHGHHHHPHRVGRVILPPTTVPYPQKRVEIRVEVPRSQGKPNHRDRFDSRGPSNNRDRGDARGPSNDRDRNRGDAGKPRYNLDRERSERKENESRKPNQRPSTSLRSDVTNDAVGRLLTSLFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWL8</accession>
    <name>A0A518IWL8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_34990</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="76"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="102"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="133"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="159"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="199" mass="20643" checksum="03FBB3991930C3A9" modified="2019-10-16" version="1">MKIFLPVLFALCTAMCWGMYGPTIGNAQSKSWSPFKPYVFIGIAYLVLAIIGGLIAMRLKGDTFSYTGEHFAPAKWGFLAGCLGALGALFLTSAMMTSKGNALLVMPIVFGGAVSVTALYSTWRLWGHVQISPVLWVGIAMVAVGVILVATNTPHGHAAAKPAPAAGAVEHGGSEQPAPADDGADSAASESTPEFDPNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWN7</accession>
    <name>A0A518IWN7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Outer membrane biogenesis protein BamB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_35190</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025666">
        <property type="entry name" value="PQQ-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018391">
        <property type="entry name" value="PQQ_beta_propeller_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002372">
        <property type="entry name" value="PQQ_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13360">
        <property type="entry name" value="PQQ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13570">
        <property type="entry name" value="PQQ_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00564">
        <property type="entry name" value="PQQ"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021719060" evidence="2">
        <location>
            <begin position="22"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="domain" description="PQQ_3" evidence="3">
        <location>
            <begin position="51"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13570"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV57509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="417" mass="44693" checksum="3DC8AE995E39A320" modified="2019-10-16" version="1" precursor="true">MRLMLLATAISFSFAVSTSRADNWGHWRGPDGNGAAANASPPTQWSDTENVKWKVAIPGKGSGSPVVWENQVFVVTAAPAANAPAETLDFLLMCFDRANGKLLWQQTATTARPHQGTHATNGFASASPCTDGQHVYAHFGSRGLYCYTMDGQLVWKRDDLGKMNTRLGFGEGSSPVLAGNKIIVPWDHEGPSALMALDKLTGQTIWNVAREEPSGWATPLIVQHDGQKQVVMNGDGYARSYDLETGEELWRCGGQTMRPGASAVAADGMIYVASGFRGAYLGAFTPDGKGDIEGTRKVVWSLGRDTPDIASPLLSEGRLYFYKGRSGLLSCLDAKTGEPHYAASRIAGINSTYASPVAAGGYVFLSGRSGRIVVIKDSPELEIVATNAMNETVDATPAPVDNELFIRGERHLFCIAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWU5</accession>
    <name>A0A518IWU5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_35450</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="SSF47473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021883439" description="EF-hand domain-containing protein" evidence="2">
        <location>
            <begin position="23"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="34"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV57535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="161" mass="16854" checksum="C79BE66A642C39FA" modified="2019-10-16" version="1" precursor="true">MNSTLRLIAISGILTYASTVSAQPPGRGGPPGGSPMEMISQLFDRADTNRDGSVTKQELSVVMQAMQSMRGGRQGGPGGPPPQGGPGAGEMTQPRPEHGGQHGPPPRPGQVIPDFVVQSLSLTDRQSKQLTALQTTVDKRLAAILTDEQMVALQQPPQGPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWZ4</accession>
    <name>A0A518IWZ4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Serine/threonine-protein kinase PknB</fullName>
            <ecNumber evidence="4">2.7.11.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">pknB_17</name>
        <name evidence="4" type="ORF">Mal33_36200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.11.1" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="110"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="135"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="168"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="206"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="230"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="271"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="3">
        <location>
            <begin position="301"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="330"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV57607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="591" mass="65675" checksum="1E3C508D863FDD4F" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IY55</accession>
    <name>A0A518IY55_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_40320</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021837030" evidence="2">
        <location>
            <begin position="21"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="247"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="279" mass="30348" checksum="B6233F0F4660C49C" modified="2019-10-16" version="1" precursor="true">MKSQPLMLLLACSLFACDLAGEEAQEPKHWDKVVAIQTKQKTTNKHATAFFIRKGDAYFMVTANHAADETKGDTRILYVREDGDSRWMQLRGIVPADTNPWTQFKNNDLAVARLQFPRASKSDIADFNYLALPYEALLTSTPPRASEIVFAGFPMAYGTTPPIRSLVVRGHIASRELKSKGDWGVVPIIYATPTVASGTSGSPVFSFMQSPDEIAIVGMYIAVAVDETGAKLAKLVPARLIREAIDAASEAPAGQDAEKESDEESSEAVEPQEAALQAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IY56</accession>
    <name>A0A518IY56_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Acetyl-CoA acetyltransferase</fullName>
            <ecNumber evidence="7">2.3.1.9</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">thlA_2</name>
        <name evidence="7" type="ORF">Mal33_40300</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the thiolase-like superfamily. Thiolase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.9" evidence="7"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003985">
        <property type="term" value="F:acetyl-CoA C-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00751">
        <property type="entry name" value="thiolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002155">
        <property type="entry name" value="Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020615">
        <property type="entry name" value="Thiolase_acyl_enz_int_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020610">
        <property type="entry name" value="Thiolase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020617">
        <property type="entry name" value="Thiolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020613">
        <property type="entry name" value="Thiolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02803">
        <property type="entry name" value="Thiolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000429">
        <property type="entry name" value="Ac-CoA_Ac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01930">
        <property type="entry name" value="AcCoA-C-Actrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00098">
        <property type="entry name" value="THIOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00737">
        <property type="entry name" value="THIOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00099">
        <property type="entry name" value="THIOLASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thiolase_N" evidence="5">
        <location>
            <begin position="5"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="domain" description="Thiolase_C" evidence="6">
        <location>
            <begin position="268"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="3">
        <location>
            <position position="88"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="346"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000429-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV58014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="391" mass="40703" checksum="F0DCEABDA12BDF16" modified="2019-10-16" version="1">MSTAYILSACRTPIGRFQGDFASVAAPDLAAVAIREAIRRTGLLVAEVDEVILGHVLSAGVGQAPARQAALRAGLPATVAACSVNKVCGSGLKAVMLADQAIRSGDVKLVVAGGMESMSRCGWLLRRGQRALGDQQLTDWMLHDGLTCAMTGHSMGAIAEQLAARAKISRPTQDRFALESHRRAIEAIDAGAFAEEIVPVAVNTKNGAIEISNDSGPRRETTLEQLAELRPVFGKEGTVTAGNASMISDGAAAVVVADASVAERSVVHPLCRIVATATSGGAPEDLFTAPVAAIREVVRKAGQSLQEIDLFEINEAFAVQMIACIDQLDIPHSRVNIHGGAIALGHPIGASGARVLVTLLNALQRHEKRLGIAALCLGGGNAVAMLVDREI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYG0</accession>
    <name>A0A518IYG0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC-2 family transporter protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Mal33_41440</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032688">
        <property type="entry name" value="ABC2_membrane_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12679">
        <property type="entry name" value="ABC2_membrane_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="15"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="125"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="191"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="221"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="293"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV58127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="323" mass="36259" checksum="2547F8A2E84E7FD8" modified="2019-10-16" version="1">MMTRVLIRKFIGEAILLWAACALALVAFNVLRVWLVSQMEMERFKAIIEQFRDYERFSPIPFDQLFSYVGRIGMTFDEPIVILCVVVWVIARGSDVVSGELGRGTLEMLLAQPVTRTQVMRAHGIVAVTGLAGLTLCVWLGIWIGIMCFTVKQTPPTPTFYIPLIGLHLPILTGPIEPIDTPMRELVSAEVFGVGVLNLFAFGFALLGISTWISSIDRYRWRAVGVTIGFYVVNVILMIASQATERLDWLKYFTYFTAYMPQEIIQHQMNLETGSPWQILISDTTGARQPGPFAATLFLLLIGVAGYSLAFRRFNRRDLPAPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYU0</accession>
    <name>A0A518IYU0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">N-acyltransferase YncA</fullName>
            <ecNumber evidence="2">2.3.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">yncA</name>
        <name evidence="2" type="ORF">Mal33_42690</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.3.1.-" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="168" mass="18592" checksum="708E330B5994C6E5" modified="2019-10-16" version="1">MLIRDAVQSDLDAIFEILNHEILTGVNTFKLDPLSPEQQQAWWQLHTADAFPVLAAEDSAAALMGWASLSPWSLTAGGYHRTSEVSVWIGEPFRGQGVGKALFAALIDRAHRIGHRVLLSKVEASNQASLALHHRFGFRDVGIMHGVGDKFDRELDVAILELDLRRSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ41</accession>
    <name>A0A518IZ41_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Soj-like protein</fullName>
            <ecNumber evidence="2">3.6.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_43680</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.6.-.-" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025669">
        <property type="entry name" value="AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13614">
        <property type="entry name" value="AAA_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_31" evidence="1">
        <location>
            <begin position="7"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="252" mass="27417" checksum="F253EC21EA04A4C5" modified="2019-10-16" version="1">MRNTMGRILCVANQKGGVGKTTTAVNLAAGLARGGYKTLLVDMDPQCNATSALGHAPAPRHPLIDPQTLRESILESSESNLDLLPGSRSFQDVDQLAKATGSEASLLRSHLETGLHSYDHVLIDCPPSLGTLTRAALAASTEVLMPIQCEYFAMEGLTQMIHVIREAIQATDGRLTFGGILLTMYDPRLELTHEVDSEVREFFGEIVFDTVVPRDVALTEAPSHGENIFQYSPRSRGAYAYTQLCMEVLGRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZB4</accession>
    <name>A0A518IZB4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Vegetative protein 296</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">yurY</name>
        <name evidence="6" type="ORF">Mal33_44530</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily. Ycf16 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03217">
        <property type="entry name" value="ABC_FeS_Assembly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010230">
        <property type="entry name" value="FeS-cluster_ATPase_SufC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43204">
        <property type="entry name" value="PTHR43204"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01978">
        <property type="entry name" value="sufC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="6"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV58432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="273" mass="30209" checksum="490EEEDCB62CA536" modified="2019-10-16" version="1">MTKPTLTITNLHVSVGDKPILRGVDLVMRHGETHAMMGPNGSGKSTLGLAIMGHPGYEVTEGSITLDDQDVLAMSPDERARGGIFMAFQRPMAIPGVKMADFLRHATTNVRNPERKEGEELIPMREFRKELKGKMEHLRMDVEFARRYVNDGFSGGEMKRAEILTMAMLQPTFAILDETDSGLDADAVRLASESIAEIGREKMGLLIITHHDKLLEHNPPEFTHVMLGGRIVETGGSELADELHTNGYDRIRKAHPEADALNQEMLSEEAVEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZE5</accession>
    <name>A0A518IZE5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">GEVED domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_44230</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002105">
        <property type="entry name" value="Dockerin_1_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036439">
        <property type="entry name" value="Dockerin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045474">
        <property type="entry name" value="GEVED"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00404">
        <property type="entry name" value="Dockerin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20009">
        <property type="entry name" value="GEVED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GEVED" evidence="2">
        <location>
            <begin position="931"/>
            <end position="1004"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1311"/>
            <end position="1337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1346" mass="142391" checksum="043274576155D347" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZJ2</accession>
    <name>A0A518IZJ2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_44780</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007386">
        <property type="entry name" value="DUF447"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04289">
        <property type="entry name" value="DUF447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="186" mass="20184" checksum="E3367D9E24B91F13" modified="2019-10-16" version="1">MILESLVTSTNASGELNVAPMGPIVDAGITQIQLRPFKTSTTYGNLRATSRAVVHVTDDVLMIAQAAIGRIEPPPEVRPIDGGWFVLEKASRWFAIEVVRWIDDPQRPTAECAIRAEGTGPPFFGLNRAKHAVVEAAILATRTHLLPAAELLADLERLQVLVDKTAGDAEREAFALLQATIRQRVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZN2</accession>
    <name>A0A518IZN2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Type II secretion system protein G</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">xcpT_14</name>
        <name evidence="1" type="ORF">Mal33_45720</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011453">
        <property type="entry name" value="DUF1559"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07596">
        <property type="entry name" value="SBP_bac_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="331" mass="35058" checksum="B241286418EDB82D" modified="2019-10-16" version="1">MRRNSSRGFTLVELLVVIAIIGILVGLLLPAVQAAREAARRMQCSNNLKQIGLALHNYHDINRSLPIGSLGFLIQGWTVPVLPFVEQQTVYDQLAIGLPNGFDVNGVNAAVVDNWTPDMFWCPSSAATPMHLRVTSGNTVKMSTMSYIGIAGAPTSATNSSDPTGAGRCISGGQGYACANGTMIPNDTVRFRDLTDGLSNTVVIGESSSWGETAAGARIEIRTSAEWGAWAGSAASTTPPNNGTSYMWSANPYCRQITSLRYPIGTTLQLSGSGGNHRDGVNNALHSMHPGGVQVARGDGGVGFLSETMEFLVLRNLCIRDDGNVIPGDVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZN9</accession>
    <name>A0A518IZN9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_45830</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="292" mass="31636" checksum="D473F78D857DA774" modified="2019-10-16" version="1">MDIRQPVQRTLVLAVLFAALGTTQDAVGVEAVSRDFNIQPLERIPAGTVITPDGAKGWSDLLLFVNGSLGKGDVDAASSTVKHYASLFNIAYMANVAKDAEGRFTLDKIGVGFTTKIDGQDVVITSDTHKSLGADLGMIGGAVFSANERALSEIVQVARYRDGAIFDAPTIMLREGEHKKVIVRFFVWVSPQGSVGTVCWVLDGYGGSRYVVPNKEIVLLRPQLVENRVMHVDGDRFTLGIPSEDAFAVVSLPPGREYKIDDDLATLIAKKRYDAQSFFDTVQKLSQSLAAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZS5</accession>
    <name>A0A518IZS5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/beta hydrolase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_46130</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="315"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="593"/>
            <end position="614"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="614" mass="68373" checksum="1351F30812255E55" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZX7</accession>
    <name>A0A518IZX7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_46700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022226322" evidence="1">
        <location>
            <begin position="20"/>
            <end position="515"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="515" mass="56777" checksum="FC572F8400349A96" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J078</accession>
    <name>A0A518J078_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transcriptional regulatory protein ZraR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">zraR_10</name>
        <name evidence="8" type="ORF">Mal33_47720</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002197">
        <property type="entry name" value="HTH_Fis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002078">
        <property type="entry name" value="Sigma_54_int"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025662">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025944">
        <property type="entry name" value="Sigma_54_int_dom_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02954">
        <property type="entry name" value="HTH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00158">
        <property type="entry name" value="Sigma54_activat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01590">
        <property type="entry name" value="HTHFIS"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00675">
        <property type="entry name" value="SIGMA54_INTERACT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00688">
        <property type="entry name" value="SIGMA54_INTERACT_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50045">
        <property type="entry name" value="SIGMA54_INTERACT_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Response regulatory" evidence="7">
        <location>
            <begin position="7"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma-54 factor interaction" evidence="6">
        <location>
            <begin position="147"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="5">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV58747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="446" mass="50514" checksum="2DFB53CFB8B9C6C8" modified="2019-10-16" version="1">MTEDTFDILFVEDDPEFSSGYVRWFEKHGHSVEHATTGQEAVRRCDQREFDIIVLDWNLPGLSGLELVQRMCEENPDTEIIVLTGEGTIEKAVESMRRGVFDFLSKPFSMNGLERRCKAALERRRLKMENARLREVIDRGRTPDRKMIGESKPMKSLYRLIDRVAPTDKAVLIQGESGTGKELVAQAIHAGSPRAQRPLVTINCAALPEQLVESELFGHEKGAFTGATAAKPGLFEIADESTLFIDEIGELPLSLQPKLLRVLEDGSLRRVGSHKQRRVNVRIVAATNRDLQQEVAEHRFREDLFYRINVMPLNLPPLRQRTGDIELLIDHFLGNDWEIEADARAALLNCQWPGNIRQLINTIDRAQILADDGIITIEDLPVEMTSRKTSVVSEKAPADSSIYAVMRAHLIDVLRREQGNKTQAAQVLGVDRRKLYRMLLQYDIGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0C1</accession>
    <name>A0A518J0C1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative ABC transporter ATP-binding protein YxlF</fullName>
            <ecNumber evidence="5">3.6.3.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">yxlF_3</name>
        <name evidence="5" type="ORF">Mal33_48140</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.6.3.-" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="26"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="64"/>
            <end position="71"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV58789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="320" mass="35880" checksum="FD04C94A6DF5487C" modified="2019-10-16" version="1">MDIDSTAVADGTEDSKAKSDSSSVVIETRSLSKVYRDFWGRKKVQALKPLDIEVKQGEIFGLLGPNGSGKSTTIKLILGLLFPTSGRVLVFDQDATETKKNERIGYLPEESYLYKFLNAEETLDFYGRLFDLSAAERAARVDELIKMVGLDKARHRQLREYSKGMTRRVGLAQALVNDPDLIMLDEPTTGLDPIGTREMKDLILRLRDQGKTILLCSHQLADVQDVCDRVAILHQGELKELGRVDELLKVKDVTEIHARGLSDAAKAEIQAVIERNGGKTDYIDNPTATMEELFLQIVRESDERPGMRRVSERELQEGDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0D6</accession>
    <name>A0A518J0D6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_48280</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="200"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="413" mass="46811" checksum="CAE1283922DAEC4F" modified="2019-10-16" version="1">MSEANQQAQAPAGTQQAQTSSTATSGSMHKYLDRALNVLDKFGLSKREDTPQEMIHLLESVKHVDEARVLAIAEVIQHMSTFNQLVRENVENIQVGNRYLEITQMFDSVREDSKMLIAQLDDGRIGFTEKWQNWWMKIRRGTPSDRFDKIIDVYRDVTTDTKDQLSREEAIMDGYIDFRFALKEAEVLASELLDKHGPTLAAAQESLAAAQTAVDEFQGEDEGSRSRLELARDEARQKFEEEDRTFQLLKDIAENLSIGYDVGETLITKLKQTHDVKDRVFRRSVTFFTTNEHVFTILGTVYTSQQGLHEVTQATEAMKEGVNKGLEDVADLGRELERAALKAGYGSTVDPESVQKLVDAISDFQIESLTMITELRKESEESTRQIRAVVEKGKKRFQETVARHAQQAEAKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0J7</accession>
    <name>A0A518J0J7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ATPase involved in DNA repair</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_48840</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
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        <property type="project" value="InterPro"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1297"/>
            <end position="1446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="923"/>
            <end position="956"/>
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    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="609"/>
            <end position="636"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
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        <source>
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        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV58859.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1785" mass="202622" checksum="3D007BCCDD23A9F7" modified="2019-10-16" version="1"> </sequence>
</entry>
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    <name>A0A518J0K5_9BACT</name>
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        </submittedName>
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
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                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="entry name" value="DUF4838"/>
        <property type="match status" value="1"/>
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            <begin position="1"/>
            <end position="22"/>
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            <begin position="23"/>
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            <dbReference type="ARBA" id="ARBA00022801"/>
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        <source>
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    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1000" mass="112541" checksum="C1677BFA91528B58" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
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            <fullName evidence="1">BFN domain-containing protein</fullName>
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    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
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                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="project" value="InterPro"/>
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        <property type="entry name" value="DUF151"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="2"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="135" mass="15056" checksum="10382A63646FC346" modified="2019-10-16" version="1">MPVQMQLARIIISEISDNQVIYLQEVDGDRQFPILIGIFEATNIDRRVKEDYKPPRPLTHDLVVNVAEALGAEVDSVVISGLKEHTYFAQLRLKKDGEIIEIDSRPSDAIAVAVTFSPPLPIYVAEEVLDDAIKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0R9</accession>
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    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="PTM">
        <text evidence="7">The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sulfatase family.</text>
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        <property type="protein sequence ID" value="QDV58943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
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        <property type="term" value="F:choline-sulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
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        <property type="term" value="F:iduronate-2-sulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
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        <property type="entry name" value="IDS"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SULFATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="5 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022196599" evidence="8">
        <location>
            <begin position="23"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase" evidence="9">
        <location>
            <begin position="29"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="modified residue" description="3-oxoalanine (Cys)" evidence="7">
        <location>
            <position position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR600917-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV58943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="522" mass="59001" checksum="BA1198EE4F43D6A3" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J112</accession>
    <name>A0A518J112_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 4">Alanine dehydrogenase</fullName>
            <ecNumber evidence="2 4">1.4.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ald</name>
        <name evidence="10" type="ORF">Mal33_50200</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>H2O + L-alanine + NAD(+) = H(+) + NADH + NH4(+) + pyruvate</text>
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            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="EC" id="1.4.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
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    <dbReference type="EC" id="1.4.1.1" evidence="2 4"/>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000286">
        <property type="term" value="F:alanine dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042853">
        <property type="term" value="P:L-alanine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05305">
        <property type="entry name" value="L-AlaDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008141">
        <property type="entry name" value="Ala_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007886">
        <property type="entry name" value="AlaDH/PNT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007698">
        <property type="entry name" value="AlaDH/PNT_NAD(H)-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42795">
        <property type="entry name" value="PTHR42795"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01262">
        <property type="entry name" value="AlaDh_PNT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05222">
        <property type="entry name" value="AlaDh_PNT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000183">
        <property type="entry name" value="Alanine_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01002">
        <property type="entry name" value="AlaDh_PNT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01003">
        <property type="entry name" value="AlaDh_PNT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00518">
        <property type="entry name" value="alaDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0520">NAD</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 4 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AlaDh_PNT_N" evidence="9">
        <location>
            <begin position="4"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="AlaDh_PNT_C" evidence="8">
        <location>
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            <end position="297"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="5">
        <location>
            <position position="96"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="5">
        <location>
            <position position="270"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="15"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
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        <location>
            <position position="198"/>
        </location>
        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
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        <location>
            <position position="203"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
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        <location>
            <position position="220"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
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        <location>
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            <end position="240"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
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        </ligand>
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            <begin position="267"/>
            <end position="270"/>
        </location>
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            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
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        <location>
            <position position="279"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
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        <location>
            <begin position="298"/>
            <end position="301"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005689"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00012897"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV58995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="368" mass="39258" checksum="E8D19C001000BAE1" modified="2019-10-16" version="1">MIVGVPAETKSDEYRVSMLPVGVEELTRRGHTVVVQAGAGLGSGLFDHDYLKAGAELVATAKDVFDRADLIIKVKEPLEPEWPLIREGQTLFNYFHFAASRALTDALLNAGANCLAYETLRDQNGRLSLLTPMSEVAGRMSVQEGAKYLEKPQMGRGILLGGVPGVAPAHITVLGGGIVGANAARIAAGFQADVAILDVNLDRLRYLDDVMPANVNVLFSDRHTIHEQLKRADLVIGAVLIPGAKAPHLVHAEDLRIMKPGSVIIDVAVDQGGCVETSRPTTHKEPTFIVDEVVHYCVSNMPGAVGRTSTFALCNATLPWVLALADKGTEAAVREIEPIRHAANILGGAVTNLAVADTFDLAYTNLHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J118</accession>
    <name>A0A518J118_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
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        <lineage>
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    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
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                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
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            <dbReference type="EMBL" id="QDV59034.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
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    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1H1</accession>
    <name>A0A518J1H1_9BACT</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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                <person name="Boedeker C."/>
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                <person name="Kohn T."/>
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                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
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                <person name="Meyerdierks A."/>
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                <person name="Lage O.M."/>
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                <person name="Merkel B.J."/>
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                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
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                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
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            <strain evidence="2 3">Mal33</strain>
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        <location>
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        <source>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="536" mass="59204" checksum="2CC85FC0F76CC7ED" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1H3</accession>
    <name>A0A518J1H3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Outer membrane biogenesis protein BamB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_52100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018391">
        <property type="entry name" value="PQQ_beta_propeller_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002372">
        <property type="entry name" value="PQQ_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13360">
        <property type="entry name" value="PQQ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00564">
        <property type="entry name" value="PQQ"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="416" mass="45069" checksum="8D00E12EE6DA1B6C" modified="2019-10-16" version="1">MKICFSKTNQRSGFLAGGRRVPRLLLASLLWVPLCLVDAAADDWPAWRGPHRDGVSHESLPADGLQVRWRGEVGTGFSSFVVADGNALTIGNSESVDTLFCFDAESGELKWRHSYDAPLDDRDFEGGPTSTPTVHEGRVYVLARQGDLFCLDLATGKVVWQQQIVDATDIRIPGWGFGGSPQVFGDRLLLTVGEAGVAVDLADGKLVWQSGDKEAGYASPVIFDWQGKTLAMFPSGRSFSAVDVATGEAIWQQRWLTSFGCNAADPIVHDGHVFLCSGYNRGCALLRLTDDDPEIVWKHKLMQNQMNGCVRIGDALYGIDGDLESEPKLKCIDWASGEVHWADDSIRPGAIAATREHLIVLTTEGALMIGKVSTAGFEPLTELKVLQGKCWTVPVLANGSIYCRTASGSVVCVALK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1P7</accession>
    <name>A0A518J1P7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Chaperone protein DnaK</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">HSP70</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Heat shock 70 kDa protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Heat shock protein 70</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">dnaK_4</name>
        <name evidence="6" type="synonym">dnaK</name>
        <name evidence="10" type="ORF">Mal33_52870</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Acts as a chaperone.</text>
    </comment>
    <comment type="induction">
        <text evidence="6">By stress conditions e.g. heat shock.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00332">
        <property type="entry name" value="DnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012725">
        <property type="entry name" value="Chaperone_DnaK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029048">
        <property type="entry name" value="HSP70_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="PTHR19375"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="SSF100920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100934">
        <property type="entry name" value="SSF100934"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02350">
        <property type="entry name" value="prok_dnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00297">
        <property type="entry name" value="HSP70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00329">
        <property type="entry name" value="HSP70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01036">
        <property type="entry name" value="HSP70_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword evidence="4 6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0143">Chaperone</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0346">Stress response</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="613"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="536"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphothreonine; by autocatalysis" evidence="6">
        <location>
            <position position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV59259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="643" mass="69743" checksum="585FC628FFD10CC6" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1S1</accession>
    <name>A0A518J1S1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_53100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="150" mass="16334" checksum="D5ACFD1D8DC1835D" modified="2019-10-16" version="1">MRFQTFCNGIVLTGLLLLAGCGDEQTAKTSLFEHDHEVAEHWPDDFADAAVKLRQRLDVSTDETADAKQAEAEIADIVSWVPEIAADTDLPEQDWIPLDNAAESLMANLRSSGNELTDANRKQTVAFCELIEEAIAKLPAPIQSPQGASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1S2</accession>
    <name>A0A518J1S2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_53120</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="58" mass="6607" checksum="7792C3B109DFDF2F" modified="2019-10-16" version="1">MGTRLNEKLQFDLLDSTYHQQHQTSSHHKTYDGSRKLCTQRELVAKIPRTAAFTSSGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1T7</accession>
    <name>A0A518J1T7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Segregation and condensation protein A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">scpA_3</name>
        <name evidence="2" type="ORF">Mal33_53270</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01805">
        <property type="entry name" value="ScpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003768">
        <property type="entry name" value="ScpA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33969">
        <property type="entry name" value="PTHR33969"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02616">
        <property type="entry name" value="SMC_ScpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="269" mass="30732" checksum="C745F45FD231340F" modified="2019-10-16" version="1">MTFRIDLPVYRGPLDLLLYLVRRSELDITTMSLANVVDQYLEYLEVLQDLDVNGVGDFIDLASTLVEFKSKAVLPQADDEQEEEVLEDPQEELVERLLEYKRFRDASSILDEMGEQWQQRYPRIADDLPPRQIDPGDQPIADLELWDLVSAFGRIMRESSGPPPTQVVYDDTPIHVYMQRIHEQLLKVDEVRFSDLFDLGAHKSAMIGIFLAILELARHYGVSTRQEAGGIDIVVTRGERFETELNVSEVDNYDASAVDETNLPIKKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1U5</accession>
    <name>A0A518J1U5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ketol-acid reductoisomerase (NADP(+))</fullName>
            <shortName evidence="8">KARI</shortName>
            <ecNumber evidence="8">1.1.1.86</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Acetohydroxy-acid isomeroreductase</fullName>
            <shortName evidence="8">AHIR</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Alpha-keto-beta-hydroxylacyl reductoisomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 12" type="primary">ilvC</name>
        <name evidence="12" type="ORF">Mal33_53290</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>(2R)-2,3-dihydroxy-3-methylbutanoate + NADP(+) = (2S)-2-acetolactate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:22068"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:49072"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58476"/>
            <dbReference type="EC" id="1.1.1.86"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>(2R,3R)-2,3-dihydroxy-3-methylpentanoate + NADP(+) = (S)-2-ethyl-2-hydroxy-3-oxobutanoate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:13493"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:49256"/>
            <dbReference type="ChEBI" id="CHEBI:49258"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.86"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="8">Binds 2 magnesium ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 2/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 2/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8 9">Belongs to the ketol-acid reductoisomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.86" evidence="8"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00047">
        <property type="reaction ID" value="UER00056"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00049">
        <property type="reaction ID" value="UER00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004455">
        <property type="term" value="F:ketol-acid reductoisomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00435">
        <property type="entry name" value="IlvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013023">
        <property type="entry name" value="KARI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000506">
        <property type="entry name" value="KARI_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013116">
        <property type="entry name" value="KARI_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014359">
        <property type="entry name" value="KARI_prok"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21371">
        <property type="entry name" value="PTHR21371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01450">
        <property type="entry name" value="IlvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07991">
        <property type="entry name" value="IlvN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000116">
        <property type="entry name" value="IlvC_gammaproteo"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00465">
        <property type="entry name" value="ilvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51851">
        <property type="entry name" value="KARI_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51850">
        <property type="entry name" value="KARI_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8 9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7 8 9" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="12" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6 8 9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0521">NADP</keyword>
    <keyword evidence="8 9 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="KARI N-terminal Rossmann" evidence="10">
        <location>
            <begin position="39"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="domain" description="KARI C-terminal knotted" evidence="11">
        <location>
            <begin position="220"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="145"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="62"/>
            <end position="65"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 9">
        <location>
            <position position="228"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8 9">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 9">
        <location>
            <position position="264"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 9">
        <location>
            <position position="268"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 9">
        <location>
            <position position="289"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QDV59301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="370" mass="40620" checksum="153EEB733B623242" modified="2019-10-16" version="1">MEPKRLLTLERPVEYKPKIVQLFKPTYATIAQGTLHMAATIYYDNDADLSHLKGKTIAIIGYGSQGHAQAQNLRDSGCDVIIGQRPGGPNYDLAKSHGFEPMSADEATAKADVVNLLLPDEVQGDIYKAQIRDNLQPGNVLMCSHGFNIHFGQIEPPTGVDTLLVAPKGPGHLVRSEYEKGGGVPSLIALGEGASEETKQIGLAYAKGIGGTRGGVIETTFQEETETDLFGEQVVLCGGLSELIKAGFETLVEAGYQPEMAYFECMHEVKLIVDLFYQGGLSYMRYSISNTAEYGDYVTGPRIITPETKAEMKRVLTEIQNGTFARNWILENRGGAAMFKTTRRLEQGHEIENVGKRLRSLMSWIDDKQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1W0</accession>
    <name>A0A518J1W0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_53520</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="109" mass="12535" checksum="C22BCB1E623BD63E" modified="2019-10-16" version="1">MLGSFLSNHPQIYWGNERFNPTFWAPLRFATIQASCTNLPCYGTKCFLHHLARVPKDDFGKRLLNEFSQAGWKTISLKRVNCFRHALSIEKALSSNRFLQLKGGPPHRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1Y2</accession>
    <name>A0A518J1Y2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Triphosphoribosyl-dephospho-CoA synthase</fullName>
            <ecNumber evidence="2">2.4.2.52</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_53730</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>3'-dephospho-CoA + ATP = 2'-(5''-triphospho-alpha-D-ribosyl)-3'-dephospho-CoA + adenine</text>
            <dbReference type="Rhea" id="RHEA:15117"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57328"/>
            <dbReference type="ChEBI" id="CHEBI:61378"/>
            <dbReference type="EC" id="2.4.2.52"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.4.2.52" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046917">
        <property type="term" value="F:triphosphoribosyl-dephospho-CoA synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002736">
        <property type="entry name" value="CitG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01874">
        <property type="entry name" value="CitG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV59345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="306" mass="32491" checksum="79DBA30F620D3A85" modified="2019-10-16" version="1">MSSKELPISSSIRQTPFDWQAAANLSVGAAVGLACTLEATAVKAGNVFPGQEFHDLGVADFLAAAAVCSCVMERADDFSTGQLVLESVQRSRAATRSNANLGIVLLLAPLAKAAAAGGRHRDIAALRQQLTLQLTNLTPEDGRLVFQAIREAAAGGLGDAESHDVNATQVDVDLLEAMRMGRDRDKIAEQYSTGFAFVFETVAPCLQRAIADEGDLLRGISRAQIALLADHIDTLIQRKCGAAIAEEAKQRARIVYDAGAFDVRSPEWIALNDWLCGDGNRRNPGTTADLIAAGLFVLIRSGFSLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J206</accession>
    <name>A0A518J206_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Chaperone protein DnaK</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">dnaK_5</name>
        <name evidence="4" type="ORF">Mal33_54000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021030">
        <property type="entry name" value="DUF3731"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="PTHR19375"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12531">
        <property type="entry name" value="DUF3731"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00297">
        <property type="entry name" value="HSP70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV59372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="935" mass="102843" checksum="7EEF98BF63A102B8" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J221</accession>
    <name>A0A518J221_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_54040</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021852943" evidence="2">
        <location>
            <begin position="22"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV59376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="56" mass="5598" checksum="5CF5C2DE2F35B140" modified="2019-10-16" version="1" precursor="true">MSFVPRSLSLLAILVAISAIGCGETNSGPVTPKPTATPTSDAPPRGPEPVLAEEGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J228</accession>
    <name>A0A518J228_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 13">Biotin synthase</fullName>
            <ecNumber evidence="3 13">2.8.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13 16" type="primary">bioB</name>
        <name evidence="16" type="ORF">Mal33_54230</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12 13">
            <text>(4R,5S)-dethiobiotin + [sulfur carrier]-SH + 2 reduced [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine = 2 5'-deoxyadenosine + [sulfur carrier]-H + biotin + 2 L-methionine + 2 oxidized [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:22060"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="Rhea" id="RHEA-COMP:14737"/>
            <dbReference type="Rhea" id="RHEA-COMP:14739"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:29917"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57586"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:64428"/>
            <dbReference type="ChEBI" id="CHEBI:149473"/>
            <dbReference type="EC" id="2.8.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13 14">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
        <text evidence="13 14">Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13 14">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="13 14">Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 13">Cofactor biosynthesis; biotin biosynthesis; biotin from 7,8-diaminononanoate: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the radical SAM superfamily. Biotin synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.6" evidence="3 13"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00078">
        <property type="reaction ID" value="UER00162"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004076">
        <property type="term" value="F:biotin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009102">
        <property type="term" value="P:biotin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01694">
        <property type="entry name" value="BioB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010722">
        <property type="entry name" value="BATS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002684">
        <property type="entry name" value="Biotin_synth/BioAB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024177">
        <property type="entry name" value="Biotin_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22976">
        <property type="entry name" value="PTHR22976"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06968">
        <property type="entry name" value="BATS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001619">
        <property type="entry name" value="Biotin_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00876">
        <property type="entry name" value="BATS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00433">
        <property type="entry name" value="bioB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13 14" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="4 13 14" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="9 13" id="KW-0093">Biotin biosynthesis</keyword>
    <keyword evidence="10 13 14" id="KW-0408">Iron</keyword>
    <keyword evidence="11 13 14" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8 13 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 13 14" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 13 16" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Radical SAM core" evidence="15">
        <location>
            <begin position="52"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13 14">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13 14">
        <location>
            <position position="74"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13 14">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13 14">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13 14">
        <location>
            <position position="146"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13 14">
        <location>
            <position position="206"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13 14">
        <location>
            <position position="276"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR001619-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="QDV59388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="335" mass="37253" checksum="4F1DA1C751041AA9" modified="2019-10-16" version="1">MQDVATGTWHGLADRVLAGESIGRDEALSILRADDTQVLDILAAAYRIRHRYHGNTVQLYFLMNAKSGLCPEDCGYCSQSKISNAPVEKYTILNREKLMDAARVAAERQAKTYCLVISARGPNEREMKAVETIVPEIKAKYDLKICACLGLLTEEHAQRLKAAGVDRVNHNLNTSENHYKEICTTHTFADRKETLHHVRNAGMELCSGGIIGMGETDDDVVDMAMELRELKVESIPLNFLNAVDGTPLEGNDQLTPAYCLKALAMFRFVNPDRELRISGGREIHLRSLQPLGLYAANSMFVGDYLTTQGQPPQADYDMIRDLGFEVTINEETVSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J234</accession>
    <name>A0A518J234_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative ABC transporter ATP-binding protein YbhF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ybhF_8</name>
        <name evidence="5" type="ORF">Mal33_54400</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="2"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="34"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV59405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="238" mass="25879" checksum="4B84D0E3FC2A9F9C" modified="2019-10-16" version="1">MIEAVGLSKFYGPFAAARDISFTVNEGELVAFLGPNGAGKSTTMKMLTGYIAASEGEARIAGHNMLSDRIEGSKRLGYLPENGPLYPEMTPASLLEFFADARGMGLRERKQHVERVVEICDLSTVMHKATSKLSKGFKQRVGMAQALLHDPDVLILDEPTAGLDPNQIRGVRATMAKLAETKTILLSTHILQEVEAMATRVVLINEGRKVYDGTVDDLGHKGQLDEAFHKLTHGESVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IM77</accession>
    <name>A0A518IM77_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">MinD/ParA/CobQ/CobA-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_01330</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025669">
        <property type="entry name" value="AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13614">
        <property type="entry name" value="AAA_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_31" evidence="2">
        <location>
            <begin position="1"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="288"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="311" mass="34981" checksum="27C3719E21E37E96" modified="2019-10-16" version="1">MAVILFTNLKGGVAKTTNAIAVAECLASSGKLTLLIDADHQCTASELLLGEQALIELDRKKRTLHDLLSEMLKPEFEAKQFDAYVRPSASNIGGGIEDLSVIPCSVRIDDFQTNYAKGGHGFHTWQDFRKLFDANRRQFRRWLKQFAYVIVDCPPSLSLQVKLFLGIADGYVVPCQPNRLSIRGLLWLSDRIHNYRYKTVCLGTLWSMCRGNDRMHKAIIEGAANNHAQLRDLPTPFETTVPLAANIAHAGELTDKQPKTFRAKYGTEFGRIYEQICEELMERVEALESERAEERGGRRQPQRKSPASVTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMI3</accession>
    <name>A0A518IMI3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF1080 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_02330</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010496">
        <property type="entry name" value="3-keto-disaccharide_hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06439">
        <property type="entry name" value="DUF1080"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022188017" description="DUF1080 domain-containing protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1080" evidence="2">
        <location>
            <begin position="36"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="254" mass="28336" checksum="233417C00FF040ED" modified="2019-10-16" version="1" precursor="true">MMRAIALSLIGFALPLAAEEFRPDQSQLPAEPPADAIVLFDGESEPKFRSTQGTAINWPIENGSLVSTVSQGEQAVRSNHLVSTLHFRDADLHVEFLIPEGGTGNSGIYIHGNYEVQIIDSHGKQELSQQDAGSVYGFSKPLANACGPRGQWQVYDIRYRAPRRDDQGKITQEGSITAWLNGQQVQHDLQLGEPRSSYHPYRYGTTPYLKAIWERQLKTSTGPLFLQDHDNAVRFRNVWVRPLDDKAFIDTSGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMP0</accession>
    <name>A0A518IMP0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_02960</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="138" mass="14588" checksum="CA58E34BF0CFFB82" modified="2019-10-16" version="1">MVFSELRLFAAIAILTVPLAVGCGGTRSDQIPVTGKVSFGGQPVEQGTITFMPVSGVGQTTGAEIVAGSYSTTVSPGEQAVQITANKTVVKENPTEEEVQRGLTESTEQYLPAKFNRQSELRVTVSADATTHDFDLQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMP1</accession>
    <name>A0A518IMP1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_03100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="111"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="154"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="191"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="224"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="259"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="297" mass="32141" checksum="4EDA92A0061BBF96" modified="2019-10-16" version="1">MTSIQINDGGDAISPADDSVCVAAAGAWPFVSRRVYKLAGEVESIWTSRQHRKSLGPRRAASSLATWVFNPQSLNWWIGCIFAIGSSLFAAGSLLTLVPQLAKASGLEANINAIFFAGSIPFTTAAWLQLFQAANAGRSPNQSRKLFGWRPHDVGWLSCALQFAGTILFNINTFDGMIPGLNWFQSGLAVWTPNILGSLLFFASGYLAWIETCHAHWSFQPREIAWWIVAINLLGCISFLLSAFWGISLPTTPEDWPTISVAFTLAGAICFLIGALLMLPEAEQSTSEPATVVAITA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMR1</accession>
    <name>A0A518IMR1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 11">Glucose-inhibited division protein A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11 15" type="primary">mnmG</name>
        <name evidence="11" type="synonym">gidA</name>
        <name evidence="15" type="ORF">Mal33_03300</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 11">NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 11">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="9 11">Homodimer. Heterotetramer of two MnmE and two MnmG subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the MnmG family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002098">
        <property type="term" value="P:tRNA wobble uridine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00129">
        <property type="entry name" value="MnmG_GidA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004416">
        <property type="entry name" value="MnmG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002218">
        <property type="entry name" value="MnmG-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020595">
        <property type="entry name" value="MnmG-rel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026904">
        <property type="entry name" value="MnmG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044920">
        <property type="entry name" value="MnmG_C_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040131">
        <property type="entry name" value="MnmG_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11806">
        <property type="entry name" value="PTHR11806"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11806:SF0">
        <property type="entry name" value="PTHR11806:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01134">
        <property type="entry name" value="GIDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13932">
        <property type="entry name" value="GIDA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00136">
        <property type="entry name" value="gidA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01280">
        <property type="entry name" value="GIDA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01281">
        <property type="entry name" value="GIDA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 11" id="KW-0274">FAD</keyword>
    <keyword evidence="5 11" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8 11" id="KW-0520">NAD</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="GIDA" evidence="13">
        <location>
            <begin position="9"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="domain" description="GIDA_C" evidence="14">
        <location>
            <begin position="405"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="206"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="607"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="14"/>
            <end position="19"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="126"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="277"/>
            <end position="291"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="374"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF13932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="QDV54376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="629" mass="69712" checksum="AD7F87DB9E47275D" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMV0</accession>
    <name>A0A518IMV0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">L-allo-threonine aldolase</fullName>
            <ecNumber evidence="6">4.1.2.49</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ltaA</name>
        <name evidence="6" type="ORF">Mal33_03710</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the threonine aldolase family.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.49" evidence="6"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008732">
        <property type="term" value="F:L-allo-threonine aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001597">
        <property type="entry name" value="ArAA_b-elim_lyase/Thr_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023603">
        <property type="entry name" value="Low_specificity_L-TA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48097:SF9">
        <property type="entry name" value="PTHR48097:SF9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01212">
        <property type="entry name" value="Beta_elim_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017617">
        <property type="entry name" value="Thr_aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta_elim_lyase" evidence="5">
        <location>
            <begin position="1"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="4">
        <location>
            <position position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR017617-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV54417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="330" mass="35510" checksum="770A3F10D16BC24B" modified="2019-10-16" version="1">MADAEVGDDVIDVDPTVQRLEQRTAELLGKEAAIYMPSGSMTNQIAIRVHCGRGEEFLCEADCHVYNYEQGAFASLSGLVARTIQGDSGVLRLDQVRGMVRPDNDHSVRTRMITLENTHNRGGGRVQPFENVKGICDWAKQEGLTRHLDGARLWNAVAATGIDEATWAAEFDSVSVCFSKGLGAPVGSALVGSHAFVQEARRARKLFGGGMRQAGIIAAGALYAIEHHRGCLVDDHAHAQLLAEAVRDSPGIDLPTPTVDTNIVIASVDPAWGTAAEFRDQLAAADVSVMAFGPQAVRFVTHRDVDRAQIDRACQAIRTVAQKNRTSVAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMY4</accession>
    <name>A0A518IMY4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_04010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011453">
        <property type="entry name" value="DUF1559"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07596">
        <property type="entry name" value="SBP_bac_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="326" mass="35199" checksum="82ED115A232F6D08" modified="2019-10-16" version="1" precursor="true">MQRTNTRTKGFTLVELLVVIAIIGILVGLLLPAVQQAREAARRIQCTNQTKQIGLALHNYHDTHRSFPPGGIVAEKVTKGVGDTWCNAGSSTQGAPWTVLILPFMEEGARYDQYDFDLPLSASYTSQVPSSSPNRPLWYEQNANYQCPSDPSSGGDVNNLSYFGVQGGGDSTTVNCWGGNSNVFFVNGILYANSSSKFRDVTDGTTNTFLVGETKYHLTEAGTVSTFYLSWASSIRLGTGGTMPHPVTLAGTYEPINSRIPTGSVPKGNTDSRTGYSRLFGSFHPGGCNMLMADASVNFVSETMDLNIYRQLGIRNDSLPIGGLPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IN43</accession>
    <name>A0A518IN43_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">2-isopropylmalate synthase</fullName>
            <ecNumber evidence="3 7">2.3.3.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Alpha-IPM synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Alpha-isopropylmalate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">leuA_1</name>
        <name evidence="7" type="synonym">leuA</name>
        <name evidence="9" type="ORF">Mal33_04630</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>3-methyl-2-oxobutanoate + acetyl-CoA + H2O = (2S)-2-isopropylmalate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21524"/>
            <dbReference type="ChEBI" id="CHEBI:1178"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.3.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 7">Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 1/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.3.3.13" evidence="3 7"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00048">
        <property type="reaction ID" value="UER00070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003852">
        <property type="term" value="F:2-isopropylmalate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01025">
        <property type="entry name" value="LeuA_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013709">
        <property type="entry name" value="2-isopropylmalate_synth_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002034">
        <property type="entry name" value="AIPM/Hcit_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036230">
        <property type="entry name" value="LeuA_allosteric_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005671">
        <property type="entry name" value="LeuA_bact_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000891">
        <property type="entry name" value="PYR_CT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00682">
        <property type="entry name" value="HMGL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08502">
        <property type="entry name" value="LeuA_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00917">
        <property type="entry name" value="LeuA_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110921">
        <property type="entry name" value="SSF110921"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00973">
        <property type="entry name" value="leuA_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00815">
        <property type="entry name" value="AIPM_HOMOCIT_SYNTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00816">
        <property type="entry name" value="AIPM_HOMOCIT_SYNTH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50991">
        <property type="entry name" value="PYR_CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 7" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="4 7" id="KW-0432">Leucine biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pyruvate carboxyltransferase" evidence="8">
        <location>
            <begin position="14"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV54509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="517" mass="56343" checksum="9FB300E8F8D96149" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IND1</accession>
    <name>A0A518IND1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histidinol-phosphatase</fullName>
            <ecNumber evidence="3">3.1.3.15</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">hisN</name>
        <name evidence="3" type="ORF">Mal33_05450</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the inositol monophosphatase superfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.15" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004401">
        <property type="term" value="F:histidinol-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046855">
        <property type="term" value="P:inositol phosphate dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011809">
        <property type="entry name" value="His_9_proposed"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000760">
        <property type="entry name" value="Inositol_monophosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020550">
        <property type="entry name" value="Inositol_monophosphatase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00459">
        <property type="entry name" value="Inositol_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00377">
        <property type="entry name" value="IMPHPHTASES"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02067">
        <property type="entry name" value="his_9_HisN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00630">
        <property type="entry name" value="IMP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="271" mass="28587" checksum="F0EA0D67C68F3125" modified="2019-10-16" version="1">MTTTPPSEWSARDEGRVAAMIDLAHAAGQLTLNFFGDATLAVDRKGDASPVTEADRSAERLIRQRVAESYGDDAILGEEFADTQGSSGYRWIVDPIDGTKSFICGVPLYSTIVAVEKDDQVIAGAIVIPALGESIVAAIGSGAWHRRNNDADWTAAHVSPCDRIEDAVFLTSQVDSFANRGAGAAYDSLQSAASITRSWGDAYGYLLVATGRADIMVDPIVNPYDVAAVQPVLTEAGGQFSDWKGNPTIRGGDAFGTNGKLHAQVLSHLGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INE2</accession>
    <name>A0A518INE2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_05500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002105">
        <property type="entry name" value="Dockerin_1_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036439">
        <property type="entry name" value="Dockerin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00404">
        <property type="entry name" value="Dockerin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63446">
        <property type="entry name" value="SSF63446"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="810"/>
            <end position="858"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="858" mass="92260" checksum="7BED20471CF63B5B" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INU2</accession>
    <name>A0A518INU2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Twin arginine translocase protein A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Mal33_07170</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003369">
        <property type="entry name" value="TatA/B/E"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02416">
        <property type="entry name" value="TatA_B_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0811">Translocation</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="52"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="77"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV54757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="92" mass="10179" checksum="534695666271857E" modified="2019-10-16" version="1">MFGLSPFELVLFGIVAILLFGSKLPEVARSLGQSYNQFRRGLSDLQGQFKISEFTNPSPTPATKLEDYDEPEYSKPVAPKFTPPPAKSPSEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INY4</accession>
    <name>A0A518INY4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Integral membrane protein TerC family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_07690</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005496">
        <property type="entry name" value="Integral_membrane_TerC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03741">
        <property type="entry name" value="TerC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="140"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="166"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="196"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="236"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="270" mass="29764" checksum="DAAF279B18AC94AF" modified="2019-10-16" version="1">MGAITELFTLANLLTLLMLIALQAVLGFDNLLYISLESKRVAEESQQKVRRMGIGLAIALRIVLLYIVVKAIKTFEDPFLTIGSDTEGAWMFGAFNLASVVEIAGGGFILYTAMKEIYHMLSVHEVGHGEESAQRTVGSAIFWIVLMNLVFSFDSILSAMALTDSIAVMAVAIVISGVLMMVMADHVSEFLKRNRMYEVLGLFILFIVGIMLVSEGGHNAHLTFFGYHVEAMQKTTFYFVLVVLVVVDIIQGRYQKKLMAQQAAEAGKHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP54</accession>
    <name>A0A518IP54_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_08230</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011453">
        <property type="entry name" value="DUF1559"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07596">
        <property type="entry name" value="SBP_bac_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="373" mass="39661" checksum="F351AB6C9D6C1437" modified="2019-10-16" version="1">MLLLRLVGVPLSISLSRKSIVKMNRRRMGFTLVELLVVIAIIGILVGLLLPAVQAAREAARRMQCSNNLKQLGISLHNYHDTYKSFVPRKQGTGTCGSPRDNCNRVSGFIGLLPFMEQQPMYDQIMAGDASVPPGGPEGWAGWAVWNQAPEGLRCPSGNYSGTPDSTNNYMFSVGDQIDNNRDRSDLRGVFAYRRGIKFAQIVDGTSNTIAMSEHLRGNFSLGSNSQPKIGVSMVGNLDPRTNPGACLDSHANGIYTDIASAKSRFGTRWTDGQTERVGFTTVTPPNGPSCFEGANVNADSAHSVIAPSSNHPGGVMSVFCDGSVHFISDTIDTGNLASVAAWKGTGGDSGISPFGVWGALGSKDGGEPSGDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP81</accession>
    <name>A0A518IP81_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Phosphomethylpyrimidine synthase</fullName>
            <ecNumber evidence="10">4.1.99.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Hydroxymethylpyrimidine phosphate synthase</fullName>
            <shortName evidence="10">HMP-P synthase</shortName>
            <shortName evidence="10">HMP-phosphate synthase</shortName>
            <shortName evidence="10">HMPP synthase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Thiamine biosynthesis protein ThiC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10 11" type="primary">thiC</name>
        <name evidence="11" type="ORF">Mal33_08610</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 10">Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>5-amino-1-(5-phospho-beta-D-ribosyl)imidazole + S-adenosyl-L-methionine = 4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine + 5'-deoxyadenosine + CO + formate + 3 H(+) + L-methionine</text>
            <dbReference type="Rhea" id="RHEA:24840"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:17245"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:58354"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:137981"/>
            <dbReference type="EC" id="4.1.99.17"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="10">Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="10">Cofactor biosynthesis; thiamine diphosphate biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the ThiC family.</text>
    </comment>
    <dbReference type="EC" id="4.1.99.17" evidence="10"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00060"/>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016830">
        <property type="term" value="F:carbon-carbon lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009229">
        <property type="term" value="P:thiamine diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.540">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00089">
        <property type="entry name" value="ThiC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037509">
        <property type="entry name" value="ThiC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038521">
        <property type="entry name" value="ThiC/Bza_core_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002817">
        <property type="entry name" value="ThiC/BzaA/B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30557">
        <property type="entry name" value="PTHR30557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01964">
        <property type="entry name" value="ThiC_Rad_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00407">
        <property type="entry name" value="phosphomethylpyrimidine_syntha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00190">
        <property type="entry name" value="thiC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 10" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7 10" id="KW-0408">Iron</keyword>
    <keyword evidence="8 10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="9 10 11" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6 10" id="KW-0784">Thiamine biosynthesis</keyword>
    <keyword evidence="5 10" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="184"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="225"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="264"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="268"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="291"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="332"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="412"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="415"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="420"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QDV54896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="443" mass="48873" checksum="BEEDED726D53A73B" modified="2019-10-16" version="1">MKETQILAARAGETTPEMEFVAKREDLAVDLVRDEVAAGRMVIPANKVHVAGRLEPMAIGIASKCKINANIGNSAVTSNEGEELEKLHYAVHHGADTVMDLSTGKNIDQIRKSIIDASPVPIGTVPIYQMLEELGGNIEDMRAQHFLDMVEHQAKQGVDYMTIHCGVLLEHLHLTVNRVTGIVSRGGSLIAKWMMVHNKQNPLYEAFDDLCDIMRQYDVTWSLGDGLRPGSIADASDAAQFAELEVLGELTKRGQDRGTQVMVEGPGHIPMHEIEMNMKKQAELCNGAPFYVLGPLVTDIAPGYDHITSAIGAALAGWHGAAMLCYVTPKEHLGLPNKEDVKQGCVAYKIAAHSADLARGRKGVQDRDDALSKARFEFDWKEQFRLSLDPETAQRYHDETLPQETFKSAHFCSMCGPKYCSMKITEEIREMAKGKQLVELPTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPF9</accession>
    <name>A0A518IPF9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AAA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_09230</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13401">
        <property type="entry name" value="AAA_22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="1">
        <location>
            <begin position="42"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="275" mass="30395" checksum="F9BAC085F3CF7BE0" modified="2019-10-16" version="1">MYKSHWNLTERPFENWSNEQFYYPSEVHQTALLKLRYGVENRRSAAVLCGESGMGKTILLDSFARQLSDDFGPVAQVVFPSLPGEQLLSYIADQWTGSTGDDSESMRGALGRIQTFLNNNVAAGKHAVLIVDEAHLLSDSQQLETLRLLLNINAGAEGSESAWTLILVGHPTLISTIERNRALDGRMSVKCVLQRLSMEQTAGYIQHRLAAVGAEIDKIFTLAALEAIQLRSSGIPRRINRLCDLGLMVAYAEDQSQVDAHHIEGVYNELVSIPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPK1</accession>
    <name>A0A518IPK1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_09870</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008969">
        <property type="entry name" value="CarboxyPept-like_regulatory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49464">
        <property type="entry name" value="SSF49464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="SSF49503"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021961777" evidence="1">
        <location>
            <begin position="20"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="256" mass="27719" checksum="88F13BBCC43FF498" modified="2019-10-16" version="1" precursor="true">MRFLIISAFVATTFLSATADAQQWGDLKVKFVFKGAAPDADKIAVTVDKEFCGKHDLVDESLVVGKDGGIQNVVVYAYDGRGGVKLPAIHPDLEGKPNTHELANKDCRFEPHIVICKAGDTLNVTNPDPVGHNCNLAFLVNAAQNFTIPPLKSKEVKLDNAEPAPIPVACNIHPWMQAKVVVLEHPYAAKSDESGTLVIKNLPTGKLAFRLYHEAAGRLSGLEVAGSEVNRRNVFEVEIKPGENDLGTVELDAKLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPL1</accession>
    <name>A0A518IPL1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Signal transduction histidine-protein kinase BarA</fullName>
            <ecNumber evidence="10">2.7.13.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">barA_1</name>
        <name evidence="10" type="ORF">Mal33_09800</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="10"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13188">
        <property type="entry name" value="PAS_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="75"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="100"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="135"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="165"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="198"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="8">
        <location>
            <begin position="288"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="9">
        <location>
            <begin position="363"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="8">
        <location>
            <begin position="430"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="6">
        <location>
            <begin position="577"/>
            <end position="799"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="7">
        <location>
            <begin position="817"/>
            <end position="932"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="7">
        <location>
            <begin position="956"/>
            <end position="1072"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="406"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="3">
        <location>
            <position position="871"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="3">
        <location>
            <position position="1003"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV55012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1073" mass="119197" checksum="140DD1B553F872E9" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPY0</accession>
    <name>A0A518IPY0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_11020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025737">
        <property type="entry name" value="Phenol_MetA_deg_put"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13557">
        <property type="entry name" value="Phenol_MetA_deg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021873554" evidence="1">
        <location>
            <begin position="21"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="346" mass="38320" checksum="B503558D71BAB25B" modified="2019-10-16" version="1" precursor="true">MKRLNVAFFMLLAAANVSSAHDEYRSRADKHAPAGLMGDHLHAPGEWMVEYKYMNMYMDGNRAGTQRLSDSEAIDFGATSNPVTNRMASPNNMTHEMHMVHIMRGMTEDITLYAMVMLPSITMDHTRGPMNPAGGGPGSLFTTHNSGFGDTTIGALIGLYTDSNDDVILNLGGSLPTGDIFRTTSIPSGGMMEQPMPYPMRLGSGTFNARPGITWKHYFDFGSFGTQFQTDLPIGRNYRGYSVSDEFRLNNWYSQLITDNFTTSIRVENLWRTNYDGADPMSPDSMISTNVESFRGGYTLNLGLGAAALVRGHLLNVEFVPMLHQDLNGIQLETDWSIVSSWSKSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPY3</accession>
    <name>A0A518IPY3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">L-fuculose phosphate aldolase</fullName>
            <ecNumber evidence="2">4.1.2.17</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">fucA</name>
        <name evidence="2" type="ORF">Mal33_11240</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="4.1.2.17" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008738">
        <property type="term" value="F:L-fuculose-phosphate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.225.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001303">
        <property type="entry name" value="Aldolase_II/adducin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036409">
        <property type="entry name" value="Aldolase_II/adducin_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00596">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01007">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53639">
        <property type="entry name" value="SSF53639"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldolase_II" evidence="1">
        <location>
            <begin position="3"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="Aldolase_II" evidence="1">
        <location>
            <begin position="214"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="413" mass="44742" checksum="F2E4E8FFF15C2261" modified="2019-10-16" version="1">MDRIYRYRMTTTSGGNLSIRDADGNIWITPARVDKGNLTRNDIVCVAADGSVDGLHPPSSEFPFHKAIYAARPDIGAIVHAHPVALVAFSICQQTPNTRLFHQAHSVCGKIGFAPYACPGSEALGASIANTFSEGCDSVILENHGVVVGGDCLASAFKRFEAFEFAGKTLIKANQLGELRFLSDAQLDQAAQRGVDFQSFDPGVASADERELRRQLCEFVQRGCRQRLLISTEGSFSARLDGDAFLITPTQKDRELLSAEDFVLVDGDRRESGKLASRAARAHQAIYKRHPHVQAIVFAHPVNATAFSATDVPFDVRTIPESYVFLRDVRRADYGVQYGSDGSIADFVTSRNPAAILENDGVLVTGSSVLDAFDRLEVLESTAEAVINAKSIGAVSAMPKSVIDELCDAFNLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQ18</accession>
    <name>A0A518IQ18_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_11660</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021987451" evidence="1">
        <location>
            <begin position="28"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="306" mass="33918" checksum="ECE4D98F0E98A920" modified="2019-10-16" version="1" precursor="true">MNSLICQLVRRALHAAALTGIAVCLMAIDSVGQEPEVELAWDDQPVVRFRKSMFQGVILSGGYVSDAGDNALSIADYKVSARLAVPLGSFQNLLVLTPSFRQYFVNAGDAIDVPDRLYETGVSLFTRYQWKPGLSILAMVSPQLRTDFETEDASWRLSGFGVIAWEWIPEVLTVSFGAAYLGRDDLPVLPAVGLDWRPNADWRLELMFPRPRLMRRIAKNGPLSETWAYASIAPGGNTFNVRRSDGRDDELTLGDIRTMLGVEQIRDGGRGWFAELGLAFARTIEYESGDEYDFDAGMFANVGVTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQ61</accession>
    <name>A0A518IQ61_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Polysaccharide biosynthesis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Mal33_11870</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002797">
        <property type="entry name" value="Polysacc_synth"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01943">
        <property type="entry name" value="Polysacc_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
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        </location>
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        <source>
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        <source>
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        </source>
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        <source>
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        </source>
    </evidence>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="QDV55217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="437" mass="46691" checksum="844A1598D5E8ED82" modified="2019-10-16" version="1">MIVGNRLLAIVTSFVSIPLLSRYLGEELFGLWMMVTGLVGFLVFADLGVGIGFQNQLIRCFATDDRKQPGVWVANSLVIMLSMLGVIVASSLLILPAMPLTRMLANASPETAAWIVPSMIAMALSFAIGLPAALIEYIGNAYQRGYWTHGLAAVGRLLGFVGVCVGGYMEATLPVLIFLFVGVPNVVNFVGLCVLWGRVPWLQPKFQSVSVVHIRQLLHVGSGMLGVRIAHAFAMQGPAIVVAQLHGFVAAGIFAVIQKLLTIPALLTSPLLIATQGAIGEAAHKQDWGWVRCHLSRITKIATLAYFSATVVVVAIGGGGVVWLLDVDAPPPDRGLLALLCIYAGLSTIRSGFGTLLTVTDRVFVQVAYRVAALVSAYAAILWFQPSVFYIMLAFVCLGELPQVVCTMCEASYVMRKGRRFNALADADAGDLAVADA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQD0</accession>
    <name>A0A518IQD0_9BACT</name>
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        <recommendedName>
            <fullName evidence="2">Beta_helix domain-containing protein</fullName>
        </recommendedName>
    </protein>
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    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
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                <person name="Overmann J."/>
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                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <location>
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            <end position="29"/>
        </location>
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        </location>
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            <begin position="173"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13229"/>
        </source>
    </evidence>
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        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
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    <sequence length="439" mass="48325" checksum="66D28C4D9C3DAC31" modified="2019-10-16" version="1" precursor="true">MKRTTKFSTPLYATWILIAIHCLPCLVDAADFHLTVQGAGRKDGSTWEHALDQQALSEVVNDTMMPGDRLLLGGGVYKDVRLTITQGGAEGSPKTIAGVDRGEGLPVFISTWSEDKPDKGATAVQIKPGAGYLVLEGLRIEDYKNCVLVSAGKEGANCPHLVFNDVDMRRFRHGFYLSGCDDLQLHGCDLRRYTKHGFRFEQGCNRVTLRQCTADCSEGDADWETKTELFPFGFIVNNGGAPNSQFVFEDCLAQNNLMPLQKNRYKNGDGFVVEGNTSDVRFTRCRAIRNQDGGFDLKVDGVQLVDCVALRNSRNIRIWKSGTLKNCFSGWATCGLWCNGGPISVDRSTFHAMRTAAVQTDDKANQPITLRNCLITSCPQTHRKTARGKVETDATVVAEEADAAYMQPSPEWDGLGTAFNSRTYPDKGYHQPLSANATN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
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    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
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        <property type="entry name" value="Acrflvin-R"/>
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        <location>
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            <end position="1092"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="QDV55339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1113" mass="122173" checksum="922A1737260D53D2" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQR1</accession>
    <name>A0A518IQR1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Manganese transport protein MntH</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_14040</name>
    </gene>
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        <lineage>
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            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
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                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="NRAMP_fam"/>
    </dbReference>
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        <property type="entry name" value="PTHR11706"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01566">
        <property type="entry name" value="Nramp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="48"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="99"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
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            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
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            <end position="244"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
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            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="379"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
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            <end position="450"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
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            <end position="478"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
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            <end position="513"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV55431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="517" mass="56881" checksum="DA20D5FE5B967741" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQX0</accession>
    <name>A0A518IQX0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Helix-turn-helix domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_14600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="88" mass="9837" checksum="D53DD2A700A468DE" modified="2019-10-16" version="1">MVAERYFTPPQAADIIGANADKVIGWIHSGELVASNVAANPNGERPRWRISEDELAKFLFRRQHPASTLPAKPKRKRHAATTAPRYFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQX4</accession>
    <name>A0A518IQX4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_14730</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="216" mass="24739" checksum="C59CE4B507887244" modified="2019-10-16" version="1">MLRKLITKAVIKRELPANPFDGEMLPLERLRLFQWMQVHRPRVVLEVGAGVGGSTFYLSEALKQYGGKLYTCDPMRKPPQDFLDRFAGTLDFRSLKSVELIDELIAQNIVPDMLFFDGPEIPELALEDLQRLEPVIPHGCLFAMHDWELIGGRNKKIISIKSEQVRPYIEQSSDWEPLEVLSGHQKNVWWTKGRWDSVGLCLYRYQGNAARATVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IR07</accession>
    <name>A0A518IR07_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">YHS domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_14860</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004879">
        <property type="entry name" value="DUF255"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03190">
        <property type="entry name" value="Thioredox_DsbH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021705232" evidence="2">
        <location>
            <begin position="20"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredox_DsbH" evidence="3">
        <location>
            <begin position="18"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="148"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="245"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="192"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV55510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="391" mass="41278" checksum="31D635645AB91A97" modified="2019-10-16" version="1" precursor="true">MRIALLLTALFVFASSSQAEIPWNADLKVAHQQAQAEGKLLLVHFESDNCVWCDRLEAGAFQSPEVAAVIGQAFVPVKINASNNKKLAEYFKVNRFPTDVVVDASGAVHAHSVSPQAPLQYVTMLQEAAAKGGRPIGAPAADPAANIAQQTPATPSPTSLQTPAVAAQPPAAEPTGPASGYGMPPSIAGNVAANAPQGQFQLPSHPGLQTPSVTPASAAISMPPSKPVQQNDGGAASIEANSFAATTATQEPATPSPEPESPSVAATPPLAMDGFCPVAILDETRWVSGDKQFGAIHLGKLYLFASAESQTKFLADPEKYTPALGGMDVVRFFENQEQVEGTREFGLHHQGQLFFFTSEDSLKRFFQSPESYSVKAQGVMHQAMSQVRQLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IR82</accession>
    <name>A0A518IR82_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_15730</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011447">
        <property type="entry name" value="DUF1552"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07586">
        <property type="entry name" value="HXXSHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="457" mass="50092" checksum="0F239A4330D31572" modified="2019-10-16" version="1">MRRMNTHATTLNRRTLLRGLGTAIALPLLDAMSPTRCLTAAAAPTNTAIPMRMAFLYVPNGMHMPDWKPTKEGSDYELPRTLKELAAHRSDFNVMTGLALKGAEAQGDGGGDHARSVAAFLTGAHPKKTDGANIQNGVSVDQVAADAIGSATRFASLELGLENSAQAGTCDSGYSCAYSSNMSWRNATSPVAKEIDPAKVFDRLFGHGDGGAVREARATRHKYRKSVLDFALQEANQLKDQLGVLDRRKLDEYLYSVRSIEKRIVGTDKLDATEEGVPDYPRPAGVPREMQKHADLMLDMMTLAMQTDSTRVISFMFTNAGSNRGYPELDVREGHHELSHHGKSEEKQTKIATINRFYAQRFAYFLERLKQVPEGDGTLLDHSAIVYGSGISDGDRHNHYDLPILLAGRAGGRIQTGRHIVYPKKTPLCNLYLWMLQQAGAPSESFGDSNAAIDRLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRH2</accession>
    <name>A0A518IRH2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Zinc carboxypeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_16760</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="F:metallocarboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000834">
        <property type="entry name" value="Peptidase_M14"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00246">
        <property type="entry name" value="Peptidase_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M14" evidence="1">
        <location>
            <begin position="55"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="domain" description="Abhydrolase_3" evidence="2">
        <location>
            <begin position="591"/>
            <end position="686"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00246"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="850" mass="95042" checksum="386E537482A0A9CB" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRI1</accession>
    <name>A0A518IRI1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FHA domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_16680</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd00060">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SSF49879"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="2">
        <location>
            <begin position="74"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="FHA" evidence="2">
        <location>
            <begin position="201"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="277" mass="30974" checksum="3EFE74E4DA3372C4" modified="2019-10-16" version="1">MNDDAPPPTQLESDEEVQRVQAELRRQAKGSAKTTADNDEKMFRPTARPPVALLVVCDDGKDSGEAIRIRGDRFSIGRTEGDLQITHDEMISSRHLAIHRQSVAGQTRLCVTDLQSRNGLFVRVTKAPLMHDAEVLIGGGHYKMDIVREEVPETVAMAGVEDLLPASTKALEGQHLPGAVIFSEIVAGRAEARTMLDRQRYVIGRGEDCDIQRPRDPFTRMQHAVLTRSERGTWVIESGNTINGIWLRVPQIVLNVGKSCEFRIGEQRFRLKFGRRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRJ6</accession>
    <name>A0A518IRJ6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">UPF0313 protein Mal33_16940</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Mal33_16940</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="6">Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the UPF0313 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01251">
        <property type="entry name" value="UPF0313"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020612">
        <property type="entry name" value="Methylthiotransferase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023404">
        <property type="entry name" value="rSAM_horseshoe"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022946">
        <property type="entry name" value="UPF0313"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024560">
        <property type="entry name" value="UPF0313_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013704">
        <property type="entry name" value="UPF0313_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32331">
        <property type="entry name" value="PTHR32331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11842">
        <property type="entry name" value="DUF3362"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08497">
        <property type="entry name" value="Radical_SAM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01069">
        <property type="entry name" value="UPF0313"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03904">
        <property type="entry name" value="SAM_YgiQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01278">
        <property type="entry name" value="MTTASE_RADICAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4 6" id="KW-0408">Iron</keyword>
    <keyword evidence="5 6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="8">
        <location>
            <begin position="319"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="638"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="663"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="333"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="337"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="340"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV55715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="677" mass="75455" checksum="5D75C2B5903040BE" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRQ0</accession>
    <name>A0A518IRQ0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">S1 motif domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_17410</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05685">
        <property type="entry name" value="S1_Tex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.650">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3500.10">
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="NA-bd_OB-fold"/>
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        <property type="entry name" value="RNaseH-like_sf"/>
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        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S1 motif" evidence="1">
        <location>
            <begin position="653"/>
            <end position="722"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="723" mass="79288" checksum="26BEEAB344B0A987" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRV5</accession>
    <name>A0A518IRV5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glutamine amidotransferase</fullName>
            <ecNumber evidence="1">2.4.2.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_17910</name>
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    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.4.2.-" evidence="1"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
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    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
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        <property type="entry name" value="Peptidase_C26"/>
    </dbReference>
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        <property type="entry name" value="PuuD-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43235">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07722">
        <property type="entry name" value="Peptidase_C26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="250" mass="27756" checksum="3CF424D94791310C" modified="2019-10-16" version="1">MTSTRPLIGINTDFRPAQQRTPAYVYLAAGYYENIQAAGGIPVILPPSDDVDAIHAAMDRLDGFVLIGGQDLDPRNDGYMLHHSMKLMHSNRETFDRIVVNEITERRMPVLGIGAGMQLLNIVQGGNLFYDIAEDLPNAVPHRDHQDPLHRHSLVVESDSLVGRVYGDGEIRVASRHHMAIDEVAPGFRVTARCPDGVIEAIESEMMDWFAVGTQFHPECEAASALDIRIFEEFVDGVKERQTGDLRLVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRW6</accession>
    <name>A0A518IRW6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_18140</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="57" mass="6065" checksum="F0407A19ADB1CFA4" modified="2019-10-16" version="1">MELLASVHFTLPRIGSGIGGFAESLGRSPAGETARARLGEFEDYSDFADLIKFTDSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IS02</accession>
    <name>A0A518IS02_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">L-arabonate dehydratase</fullName>
            <ecNumber evidence="3">4.2.1.25</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">araC_1</name>
        <name evidence="3" type="ORF">Mal33_18570</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the IlvD/Edd family.</text>
    </comment>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
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        <property type="term" value="P:carboxylic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
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        <property type="term" value="P:primary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042096">
        <property type="entry name" value="Dihydro-acid_dehy_C"/>
    </dbReference>
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        <property type="entry name" value="DiOHA_6PGluconate_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020558">
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        <property type="entry name" value="IlvD/EDD_N"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ILVD_EDD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="578" mass="63022" checksum="B67BAB417F11A9F0" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISJ1</accession>
    <name>A0A518ISJ1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Proton glutamate symport protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">gltP</name>
        <name evidence="9" type="ORF">Mal33_20190</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046942">
        <property type="term" value="P:carboxylic acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001991">
        <property type="entry name" value="Na-dicarboxylate_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018107">
        <property type="entry name" value="Na-dicarboxylate_symporter_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036458">
        <property type="entry name" value="Na:dicarbo_symporter_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00375">
        <property type="entry name" value="SDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118215">
        <property type="entry name" value="SSF118215"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00714">
        <property type="entry name" value="NA_DICARBOXYL_SYMP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0769">Symport</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="83"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="172"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="211"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="244"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="378"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="431"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV56040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="451" mass="47777" checksum="82002597B343C4A0" modified="2019-10-16" version="1">MSSPRLALHWQILLGMLAGLLFGLLASHFGWTEFTTNWIKPFGQIFVNMLKLIAIPLIITSLIKGVSDLQDISKFSRMGGRTILLYLCTTIVAVTLGLVVANVVAPGRSITEQTRNDLLGSAGGGPAGEGQSQQIDKIKAEAAATKSQGPLQPLVDIVPDNIFSASSSNRNMLQVIFFVVFFGIGLILIPSESAKPVKDFFDGLNEVILKLVDLIMLAAPFGVFALLSALIVDAPGSDLLIALSVYAFCVLLGLGLMAFVFYPALVVMFTGRSYVSFFRGISPAQLLAFSTSSSAATLPVTMERVQEHLGVDEEVASFVLPVGATVNMDGTSLYQAVAAMFIAQAYNIDMTLGDQVTIVLTATLASIGSAAVPGAGMVMLVIVLGAIGVPEEGLALIFAIDRLLDMCRTTVNVTGDATVAMLIAKSVGMLHDPPEDHDPTPSEVLTKEQPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISJ4</accession>
    <name>A0A518ISJ4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">3-methyl-2-oxobutanoate hydroxymethyltransferase</fullName>
            <ecNumber evidence="5">2.1.2.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Ketopantoate hydroxymethyltransferase</fullName>
            <shortName evidence="5">KPHMT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 9" type="primary">panB</name>
        <name evidence="9" type="ORF">Mal33_20020</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + 3-methyl-2-oxobutanoate + H2O = (6S)-5,6,7,8-tetrahydrofolate + 2-dehydropantoate</text>
            <dbReference type="Rhea" id="RHEA:11824"/>
            <dbReference type="ChEBI" id="CHEBI:11561"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="EC" id="2.1.2.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5 8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="5 8">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Cofactor biosynthesis; (R)-pantothenate biosynthesis; (R)-pantoate from 3-methyl-2-oxobutanoate: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 5">Homodecamer; pentamer of dimers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the PanB family.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.11" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00028">
        <property type="reaction ID" value="UER00003"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003864">
        <property type="term" value="F:3-methyl-2-oxobutanoate hydroxymethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015940">
        <property type="term" value="P:pantothenate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06557">
        <property type="entry name" value="KPHMT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00156">
        <property type="entry name" value="PanB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003700">
        <property type="entry name" value="Pantoate_hydroxy_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20881">
        <property type="entry name" value="PTHR20881"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02548">
        <property type="entry name" value="Pantoate_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000388">
        <property type="entry name" value="Pantoate_hydroxy_MeTrfase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00222">
        <property type="entry name" value="panB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3 5" id="KW-0566">Pantothenate biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 9" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Alpha-ketoisovalerate binding" evidence="5 7">
        <location>
            <begin position="49"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5 6">
        <location>
            <position position="183"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5 8">
        <location>
            <position position="49"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 7 8">
        <location>
            <position position="88"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5 7">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>3-methyl-2-oxobutanoate</name>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 8">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000388-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000388-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000388-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV56023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="265" mass="28074" checksum="94AD1564F98D1754" modified="2019-10-16" version="1">MSETIRPVTTQTLSKMAAKGERIAMLTAYDFPTARLLDEAGIDVLLVGDSLAMVVQGHETTLPVTLDQIIYHAEMVGRAARRALVVVDLPFPEGQLEVGRTLAAGARILKETRCRAVKLEGGSEQAHRIEALVTAGIPVMAHVGLRPQNIHIDGGYRVQRDAQQLISDAQAAADAGAFAVLIECVPAEIAAQITAAIQVPTIGIGAGGDVDGQVLVTNDLIGLTNGYLPRFVKQYSDVGGTISSAVQQYAAEVKNGNYPGPEHQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISL6</accession>
    <name>A0A518ISL6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Arylsulfatase</fullName>
            <ecNumber evidence="7">3.1.6.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Mal33_20670</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="PTM">
        <text evidence="1">The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.</text>
    </comment>
    <dbReference type="EC" id="3.1.6.1" evidence="7"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004065">
        <property type="term" value="F:arylsulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010496">
        <property type="entry name" value="3-keto-disaccharide_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032506">
        <property type="entry name" value="DUF4976"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06439">
        <property type="entry name" value="DUF1080"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16347">
        <property type="entry name" value="DUF4976"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022114525" evidence="3">
        <location>
            <begin position="21"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase" evidence="4">
        <location>
            <begin position="24"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4976" evidence="6">
        <location>
            <begin position="359"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1080" evidence="5">
        <location>
            <begin position="490"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="709"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="modified residue" description="3-oxoalanine (Cys)" evidence="1">
        <location>
            <position position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR600917-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF06439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF16347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV56088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="729" mass="82140" checksum="E6CB601CB88B595A" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISR3</accession>
    <name>A0A518ISR3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_21070</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="143" mass="16219" checksum="D9726A418CA089E2" modified="2019-10-16" version="1">MFLLPIVILLFRASPSERRSVVSLMFAALFLFGIPTSVGWGAEFEDNKAGSLRREGSQLTGVAGEVMPVGNRWVFVGSDQRTYRLHENLALQRIVHSLRRDHADTHWTVDGTITEFMDENFLQLSRATRTSQSKRTEKKTPKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISU4</accession>
    <name>A0A518ISU4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Y1_Tnp domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_21450</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002686">
        <property type="entry name" value="Transposase_17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036515">
        <property type="entry name" value="Transposase_17_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM01321">
        <property type="entry name" value="Y1_Tnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143422">
        <property type="entry name" value="SSF143422"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Y1_Tnp" evidence="1">
        <location>
            <begin position="13"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="357" mass="40614" checksum="18F6543A8E944041" modified="2019-10-16" version="1">MTMARKYLVDPAVTRWYHCISRCVRQAFLLHEDGNETQCDWRQWIEDRLQKLDANFAISVGGFSVMDNHLHVLCRLDYEVADRWSPQEVVRRWIAVYPPKTLKSNDGNVVRKWIADHAKDQRRVTQLRDRLKNLGWFMKSLKEPLARLANKADDCHGTFWEARYKSIAILDDAALLSTGVYIDLNPLAAGIASAPEESLHTSIRKRVQHVCEKGEKEIERLKAARRGSVAASLTAGSMEQDLWLVPIEDRRSVELDEAARESCREGMLESFPLGSYLLLLDYTGRLFHEGKANMEAGVKEIFERLSSSLEAWQTRTDRMLHSKSLRGSFSASNNATVAAIATAPGHHFRNLSPQPPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISY1</accession>
    <name>A0A518ISY1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein-export membrane protein SecG</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Mal33_21830</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Involved in protein export. Participates in an early event of protein translocation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the SecG family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015450">
        <property type="term" value="F:protein-transporting ATPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004692">
        <property type="entry name" value="SecG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03840">
        <property type="entry name" value="SecG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00810">
        <property type="entry name" value="secG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="59"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="134"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="160"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QDV56202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="223" mass="22536" checksum="EE450E442AFE8A1E" modified="2019-10-16" version="1">MTALVFASMAGVFFGLTLSTLSLFLILLVLVQRGKGGGLTGALGGPGGQSAFGTKAGDLFTKITSVVALVWIFLCGASVYVMGNALPPVDNAVVVESPSLEGLDAAGEMVDESAAVALPGDDEEVVSEELVDQSDVAVPGDSEEAAMTEQPAAEAAKTEEPAAEAPKAEEPAAEAPKTEEPKAEAPKTEEPAAEAAKAEEPAAEAPKAEEPKADAPESEKAGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IT85</accession>
    <name>A0A518IT85_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Signal transduction histidine-protein kinase BarA</fullName>
            <ecNumber evidence="7">2.7.13.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">barA_3</name>
        <name evidence="7" type="ORF">Mal33_22790</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
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    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="CheY-like_superfamily"/>
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        <property type="entry name" value="HATPase_C"/>
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        <property type="entry name" value="HATPase_C_sf"/>
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        <property type="entry name" value="His_kinase_dom"/>
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        <property type="entry name" value="HisK_dim/P"/>
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        <property type="entry name" value="HisK_dim/P_sf"/>
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        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
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    <keyword evidence="7" id="KW-0808">Transferase</keyword>
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        <location>
            <begin position="676"/>
            <end position="707"/>
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        </location>
    </feature>
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    </evidence>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="841" mass="92597" checksum="49A23353221B8DB1" modified="2019-10-16" version="1"> </sequence>
</entry>
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    </protein>
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            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
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                <person name="Spormann A.M."/>
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                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56290.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
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    </evidence>
    <sequence length="130" mass="14729" checksum="36D64F9EBE6E9F8F" modified="2019-10-16" version="1">MAEITTRILQVIEVPRSLISDFIKMPESRQVAIYFLVAGSDSGDDLQIYVGQTGDLRARLAKHNKDKEFWERALSVISGTNSLTQTQTLFHEWHCIQAVRDAERYSDHNGNSGTRPYPPAPLEADCFEVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITC7</accession>
    <name>A0A518ITC7_9BACT</name>
    <protein>
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            <fullName evidence="3">4'-phosphopantetheinyl transferase sfp</fullName>
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        <name evidence="3" type="primary">sfp</name>
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        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
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                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
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                <person name="Luecker S."/>
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                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
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                <person name="Jetten M.S.M."/>
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                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
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        <property type="evidence" value="ECO:0007669"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="245" mass="27559" checksum="5152FE5832E56186" modified="2019-10-16" version="1">MFLSPPLSPNIVHLWRIDLEPSDGPFPDCLVPENDLLAREVLSDEEFAKASRFVSQPLRLRYAAAHVAMRFILGSYLEQPAAEVVLAVEKMGRPIVDFAAMQLAPSLFFNLSHTEDIALLAVGSQNPLGVDIEAIREMKSRPGIDRQVYTETERQRLLDANDSLWFDHWTAKEAVLKATGYGFYLSPLQIEIDPTLRFAVANEKSGASRWLLHRCPPSSRWSATLATSSPIEAIDQLEFPWQQIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITD3</accession>
    <name>A0A518ITD3_9BACT</name>
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        <submittedName>
            <fullName evidence="3">Bacterial membrane flanked domain protein</fullName>
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    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005182">
        <property type="entry name" value="DUF304"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03703">
        <property type="entry name" value="bPH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="domain" description="bPH_2" evidence="2">
        <location>
            <begin position="54"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="177" mass="20291" checksum="89C762B7AA725477" modified="2019-10-16" version="1">MTESPPPTQPSDAVFDASKITRPDDSLLVYYALVAACTVIGFPFVFIPLWIRFKTLSYRFDDTGVSMCWGYFFRREVHLTYRRLQDIHVTRNIVERWMGLSKLPLQTASGTAGATMQIEGIRDPEPLRDFLYAQMRGARNDSLDPESVDSDDQVLGVLTEIRDELRRIRNVPEGDDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITP8</accession>
    <name>A0A518ITP8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AbiTii domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_24510</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041304">
        <property type="entry name" value="AbiTii"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18864">
        <property type="entry name" value="AbiTii"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AbiTii" evidence="1">
        <location>
            <begin position="3"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="287" mass="31585" checksum="8A0ABEBD73DD7B30" modified="2019-10-16" version="1">MQSLVLELQRLASEDATSLPELLRKALIVAKKLGLPEFESWINNELNGYPNKIVPAYREIRGTLRVRHPYRGPIPFHLADAEMDLLITTVPCSSGVSDLFALISEGSGTEVVANIPHEMKTYLMQIQESQMPFEPMVVIGKNHFSQILDAIRTKVLNWSLELEAQGISGENMTFSRQEKEKAHSSITITNFQGVLGDVESSTLNLKMQIGDLTSLTRTLKEKGVADAEIAELEDAITKDGARDRNLGPEVSKWVGKMTAKAADGSWQIGIGAAGQLLATALQLYYGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUY1</accession>
    <name>A0A518IUY1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_28950</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="75" mass="8272" checksum="74ADA8A5976EE23B" modified="2019-10-16" version="1">MPYSFWLPFLSGEPIVREIVAPDGTPCCVEINAFWDDKPNGDIRVILSIDDGGRDALMPYGHDFILSPDGSFVGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUZ1</accession>
    <name>A0A518IUZ1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_28960</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="132" mass="14096" checksum="7D4CE70A3C1354CE" modified="2019-10-16" version="1">MTDLDGDAIIAKYCNALGGRARYDADLSATVLADLSCAIVMVNAFWSGPSMQTLVRIANVIADVDVDCRIELIVCDTDHIPDLSLEPWGLNTLGGYGEIAWVHNGQIVARRDPGRAPDLTTTTCSLLASCEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUZ8</accession>
    <name>A0A518IUZ8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative DNA-binding transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_29150</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015292">
        <property type="entry name" value="Tscrpt_reg_YbiH_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09209">
        <property type="entry name" value="CecR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="18"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="210" mass="23490" checksum="7A2F567222C8C460" modified="2019-10-16" version="1">MLNAAGRVFAARGYQNATVREICAAAGVNIASVAYYFGDKMGLYRAVVRLIRDEESRRFPIPDPAVQTDPTERLFAFVRTLLQRMFDTNEDDGWQVRLLIRELQQPTEAMEDIVKDHFAPIQDQLYQNLAELVGEPIDPSSLMHLSFTVIGQCFHYGVCENAVNALLIQRGLAAELDIDELAVHITSVAMAAAANAGFVKHQARLRELIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVD0</accession>
    <name>A0A518IVD0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Assimilatory nitrite reductase [NAD(P)H] small subunit</fullName>
            <ecNumber evidence="5">1.7.1.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">nasE</name>
        <name evidence="5" type="ORF">Mal33_30400</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.7.1.4" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008942">
        <property type="term" value="F:nitrite reductase [NAD(P)H] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00355">
        <property type="entry name" value="Rieske"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="SSF50022"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
        <property type="entry name" value="RIESKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rieske" evidence="4">
        <location>
            <begin position="7"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV57039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="108" mass="11754" checksum="25B3B5E979575FBC" modified="2019-10-16" version="1">MNAAENWTTIAKSEEIEEGIGREFLVGTRIVAVFRVDGQLFAIDGICPHQGGPLADGAVRDGCVTCPWHGWQFELTSGRHTISGRSLAETFPIRDRDGSVELIVADEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVF0</accession>
    <name>A0A518IVF0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_30650</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="90" mass="10241" checksum="52BBED52DB3604E6" modified="2019-10-16" version="1">MFGRIVNVAERTIAKVESGNADADKLIRPYNEVYRLWEALGNLVDPESLGLWFQTPNDSFDGLKPVEVIERGEIDRLWDMVFELQTGMPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVF2</accession>
    <name>A0A518IVF2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Cob(I)yrinic acid a,c-diamide adenosyltransferase</fullName>
            <ecNumber evidence="1">2.5.1.17</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">cobO</name>
        <name evidence="1" type="ORF">Mal33_30600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.5.1.17" evidence="1"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008817">
        <property type="term" value="F:cob(I)yrinic acid a,c-diamide adenosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00561">
        <property type="entry name" value="CobA_CobO_BtuR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003724">
        <property type="entry name" value="CblAdoTrfase_CobA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02572">
        <property type="entry name" value="CobA_CobO_BtuR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015617">
        <property type="entry name" value="Adensltrnsf_CobA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00708">
        <property type="entry name" value="cobA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="204" mass="22599" checksum="F9C54DDC7B9B24B7" modified="2019-10-16" version="1">MTDETNEEHRKRMVRINEIKDRQLASATKEKGLVIVHTGAGKGKSTAAFGMAIRALGQGMKVGIVQFIKGAIPTGEAEFIKQISATGMPIEMHTMGEGFTWKTQDRERDIATAMKGWDQAVQLMRDPSFDLIVLDELNIATKYDYVPASVVVDELLAKRPMLHVVVTGRNASPELIEIADLVSEMKVIKHPYAHGIQPQRGVEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVH5</accession>
    <name>A0A518IVH5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_30910</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="30" mass="3252" checksum="433CC23CCACB8D83" modified="2019-10-16" version="1">MPPVATSRLRWLTVQGGQLESASLLLQVIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVJ1</accession>
    <name>A0A518IVJ1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Uroporphyrinogen decarboxylase</fullName>
            <shortName evidence="8">UPD</shortName>
            <shortName evidence="8">URO-D</shortName>
            <ecNumber evidence="4 8">4.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8 12" type="primary">hemE</name>
        <name evidence="12" type="ORF">Mal33_31070</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>4 H(+) + uroporphyrinogen III = 4 CO2 + coproporphyrinogen III</text>
            <dbReference type="Rhea" id="RHEA:19865"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57308"/>
            <dbReference type="ChEBI" id="CHEBI:57309"/>
            <dbReference type="EC" id="4.1.1.37"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 4/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8 9">Belongs to the uroporphyrinogen decarboxylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.37" evidence="4 8"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00321"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004853">
        <property type="term" value="F:uroporphyrinogen decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004852">
        <property type="term" value="F:uroporphyrinogen-III synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd06578">
        <property type="entry name" value="HemD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00717">
        <property type="entry name" value="URO-D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10090">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00218">
        <property type="entry name" value="URO_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036108">
        <property type="entry name" value="4pyrrol_syn_uPrphyn_synt_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003754">
        <property type="entry name" value="4pyrrol_synth_uPrphyn_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038071">
        <property type="entry name" value="UROD/MetE-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006361">
        <property type="entry name" value="Uroporphyrinogen_deCO2ase_HemE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000257">
        <property type="entry name" value="Uroporphyrinogen_deCOase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02602">
        <property type="entry name" value="HEM4"/>
        <property type="match status" value="1"/>
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</entry>
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
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                <person name="Kohn T."/>
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                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
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    <sequence length="6572" mass="688912" checksum="7E244FF28554A7E7" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
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    <name>A0A518IVM9_9BACT</name>
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        </submittedName>
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
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                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
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                <person name="Bunk B."/>
                <person name="Jeske O."/>
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                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
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                <person name="Ovreas L."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <location>
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        </location>
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        </source>
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        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVN1</accession>
    <name>A0A518IVN1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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    </gene>
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        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetia</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <location>
            <begin position="219"/>
            <end position="240"/>
        </location>
    </feature>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
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            <begin position="361"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="811" mass="84085" checksum="74466DC9C750FF70" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVR6</accession>
    <name>A0A518IVR6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_31750</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011447">
        <property type="entry name" value="DUF1552"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07586">
        <property type="entry name" value="HXXSHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="441" mass="49012" checksum="3EF5259A8FF9FA00" modified="2019-10-16" version="1">MNHRNLGRRELLRKLGVSAAAIPFLSNLPSIASAAKANRRKQRLVIMFSPNGTIPDEFWPDQEGSDFELKRILAPLEPYKDRLLTLHGICNKVKGDGDSHMRGMSCLLTGTHLFPGNIQGGSHTPAGWASGISIDQEIKNFLQSNPETQTRFGELLFGVNVGDRADPWTRLSYAGPNKPVAPIEDPYRMFEKMYGRVEDQATIRSVLDSVQEDLRRVRGLISREDRRLLDEHESFVREMEKELKAGGKQTYAVSVPELESGVKNENDNAPLLGKMQIELMVNGLANDMNRVAVLQYTKSVGGARMNWLGIDENHHSLSHEPDDNEAAKEKLVKINTWFCEQLVYLAKRLDETPEPGGQGSLLDNTTIVWTNELGKGNSHTLNNIPFVMLGGGLGFKMGRSLKYNKQNHNRLLAAIANGMGHEITTFGDPNLCSDGVLTDLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVV3</accession>
    <name>A0A518IVV3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_32080</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="74" mass="8142" checksum="ABBD97E477D498B4" modified="2019-10-16" version="1">MPTSQPMPQAYPPLLTKQQTAELYATTTRTIDRWLLEKVLPSDAKVIIGGSVRFRTAVLIDHINGSTTDTPEGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IW09</accession>
    <name>A0A518IW09_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5 7">50S ribosomal protein L15</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 10" type="primary">rplO</name>
        <name evidence="10" type="ORF">Mal33_32740</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Binds to the 23S rRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uL15 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01341">
        <property type="entry name" value="Ribosomal_L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036227">
        <property type="entry name" value="L18e/L15P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030878">
        <property type="entry name" value="Ribosomal_L15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005749">
        <property type="entry name" value="Ribosomal_L15_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001196">
        <property type="entry name" value="Ribosomal_L15_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021131">
        <property type="entry name" value="Ribosomal_L18e/L15P"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12934">
        <property type="entry name" value="PTHR12934"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00828">
        <property type="entry name" value="Ribosomal_L27A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52080">
        <property type="entry name" value="SSF52080"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01071">
        <property type="entry name" value="rplO_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00475">
        <property type="entry name" value="RIBOSOMAL_L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L18e/L15P" evidence="9">
        <location>
            <begin position="27"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV57270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="170" mass="18610" checksum="BFF239A335BF005F" modified="2019-10-16" version="1">MKLHDVNTGITKNRKRKRIGRGPGSGHGKTAGRGHKGHKSRSGYSRKPSFQGGSMPLFRRIPKRGFNNAFAPTIKVMNVADLEALCDDGMEITPELLTSTRVLTGIFDELKILGNGELTKKLKVSAHRFSKSAVEKIKAAGGEVTILTAKRLPKERAELLKSGEVQRAHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IW96</accession>
    <name>A0A518IW96_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_33730</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="SSF46565"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="178"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="223" mass="23758" checksum="CE6F20724FB3B912" modified="2019-10-16" version="1">MFDSLQTWFGIPPQEQPANHYRLLGIELFESSVETIDAGFEQRMTYLHGCSTGEHAEQAEKLMNEVSAARLILLNPEKKASYDASLRRSLAAPVVAVAAAPVVPAAPAAPISPPARPAPPRQARPTLAPPVRPSAPQNPFGSLSPRSATDAKNFAIRTPKSDSRDAETPKSDRNAQSWIIVGFSVLVSCLLLGLVALILALVNPYVPPSPGQSQPSAVRNSAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWB0</accession>
    <name>A0A518IWB0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_33720</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.600">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1610">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010621">
        <property type="entry name" value="DUF1214"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037049">
        <property type="entry name" value="DUF1214_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010679">
        <property type="entry name" value="DUF1254"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037050">
        <property type="entry name" value="DUF1254_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06742">
        <property type="entry name" value="DUF1214"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06863">
        <property type="entry name" value="DUF1254"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1254" evidence="2">
        <location>
            <begin position="95"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1214" evidence="1">
        <location>
            <begin position="364"/>
            <end position="475"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="498" mass="54267" checksum="F72F574F1AD66F65" modified="2019-10-16" version="1">MKQTKSVIPHGTLARRLVAVALTTTLFVGCNKQGDTISSAEEADKKAGIAAPGIEETKAIAEEGFIYGLPIVMNYAVMNEFSVDKNSGQFKAPFNVLNSEARVATYKDTAVVTPNSDTPYSFLWLDLRSEPMVISVPAVEKDRYYSVQLIDGNTYNYGYIGNRSTGTEAGKYLAVGPDWKGDKPAGIDKVFRSSTPFGVTLFRTQLFNPADMPNVVKVQAGFKAQPLSAFLNQPAPPAAPEIDFIPATTKGIKKNFYEYLDAALATVPETPENKPVREKLASIGIGPGKSFEFKDLSDEHKAAVLLGMKEGDDKVKAFIAGAGKDQNGWQVGGVSGGDHAYYNNDWLKRAATASAGLYANDAAEATYPLTRKDADGEELDTSKHNYTLTFDEGKLPPVNAFWSVTMYDGKSQLLIENPIDRYLINSPMLPDMKKNDDGSVTLYIQKESPGADKESNWLPAPNDTAYLVMRLYWPKTEAPSILPPGEGTWQPPGIVKTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWC4</accession>
    <name>A0A518IWC4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">Elongation factor Tu</fullName>
            <shortName evidence="7">EF-Tu</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">tuf</name>
        <name evidence="9" type="ORF">Mal33_33890</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01884">
        <property type="entry name" value="EF_Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03697">
        <property type="entry name" value="EFTU_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00118_B">
        <property type="entry name" value="EF_Tu_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041709">
        <property type="entry name" value="EF-Tu_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033720">
        <property type="entry name" value="EFTU_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004541">
        <property type="entry name" value="Transl_elong_EFTu/EF1A_bac/org"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004160">
        <property type="entry name" value="Transl_elong_EFTu/EF1A_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03143">
        <property type="entry name" value="GTP_EFTU_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="SSF50465"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00485">
        <property type="entry name" value="EF-Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 7 9" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="5 7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="8">
        <location>
            <begin position="10"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="19"/>
            <end position="26"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="83"/>
            <end position="87"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="138"/>
            <end position="141"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV57383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="398" mass="43140" checksum="4E5C66B961E58585" modified="2019-10-16" version="1">MAKETFERTKPHVNVGTIGHIDHGKTTTTGAILAVQAAKGLAKAKGYSDIAKGGTVRDSTKTVTIAVAHVEYETAARHYAHIDCPGHADFVKNMITGAAQMDGAILVVSAADGPMPQTKEHVLLARQVGVPYIVVFLNKVDLVDDPELLELVELEVRELLSKYDFPGDDVPVIQGSALPAYNNPADPDASKCISDLMDALDEYVPEPSREEDRPFLMAIEDVFSIEGRGTVATGRIERGVINVGEEVEIVGFHEESKKTICTGVEMFRKQMDKGIAGDNVGCLLRGVKREEIERGQVLSKPGSITPHTKFEAEVYCLSKDEGGRHTPFFSGYRPQFYFRTTDVTGTANLVGAEMCMPGDNVKVEVELHKPIAMDDGVRFAIREGGRTVGSGVVTKILA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWX9</accession>
    <name>A0A518IWX9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_36020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="173" mass="19534" checksum="6E9BD09D5CEB61D0" modified="2019-10-16" version="1">MPTIDPAGITDGSRWFEQSEHHRKLSRIRSMPPTGSHKNLRPLRERRPSLALHSGAAPLRIDLPLTSWPVREPHTLQPIGRFAIGLGTGIDWIWDRLRFKLGIGDRHQLDWRGWIVFGTGTNRNGDRHKPLRTCGMRQAGLGTGMYCIGDRPPNRPGGFRRVQGQAWNGELIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IX22</accession>
    <name>A0A518IX22_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NADH dehydrogenase</fullName>
            <ecNumber evidence="2">1.6.99.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ndh</name>
        <name evidence="2" type="ORF">Mal33_36550</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.6.99.3" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017584">
        <property type="entry name" value="Pyridine_nucleo_diS_OxRdtase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03169">
        <property type="entry name" value="Nterm_to_SelD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="1">
        <location>
            <begin position="12"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="383" mass="41732" checksum="7FC2CA7BBCE79B08" modified="2019-10-16" version="1">MSPKLDEAPTKNIVLLGMGHTNADIAHRWQEDPIPGCRLTCISKFPTATYSGMLPGTLGQQFRDDEMRIDLASLADRAGADFVLADTSGLDLDAGQIHFHDHPSIPFDLLSIGVGSMPAGWAEYSDSPLMVPIKPMQTFLQRLDARLQTASRSAGGPMRVAIVGGGVASVEIACCLQARAGKSDNNGSLAIEIFTSSEHIADGMTPRSINRIERLLERRGINVQRSRRVVEVGETDLATDDGQRHVADCVIWATGAAAPPVLQQLGLQTDDRGFIATAATLQSLTDPRIFAVGDAGTIVASPSPKAGVYAVRQCPVLWDNLNASIAGQPLYEFDPQSDFLKILNTGDGKALLEFGRWTAHSRWCWWLKTWIDRRFVQKFQRPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IX70</accession>
    <name>A0A518IX70_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Thioredox_DsbH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_37050</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02955">
        <property type="entry name" value="SSP411"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004879">
        <property type="entry name" value="DUF255"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024705">
        <property type="entry name" value="Ssp411"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42899">
        <property type="entry name" value="PTHR42899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03190">
        <property type="entry name" value="Thioredox_DsbH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006402">
        <property type="entry name" value="UCP006402_thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022246178" description="Thioredox_DsbH domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredox_DsbH" evidence="2">
        <location>
            <begin position="30"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="645" mass="71999" checksum="2AAB023F5AD4BD56" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IX78</accession>
    <name>A0A518IX78_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glycerol kinase</fullName>
            <ecNumber evidence="5">2.7.1.30</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">ATP:glycerol 3-phosphotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Glycerokinase</fullName>
            <shortName evidence="5">GK</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 9" type="primary">glpK</name>
        <name evidence="9" type="ORF">Mal33_37030</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + glycerol = ADP + H(+) + sn-glycerol 3-phosphate</text>
            <dbReference type="Rhea" id="RHEA:21644"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17754"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.30"/>
        </reaction>
    </comment>
    <comment type="activity regulation">
        <text evidence="5">Inhibited by fructose 1,6-bisphosphate (FBP).</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Polyol metabolism; glycerol degradation via glycerol kinase pathway; sn-glycerol 3-phosphate from glycerol: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the FGGY kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.30" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00618">
        <property type="reaction ID" value="UER00672"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004370">
        <property type="term" value="F:glycerol kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019563">
        <property type="term" value="P:glycerol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006072">
        <property type="term" value="P:glycerol-3-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00186">
        <property type="entry name" value="Glycerol_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000577">
        <property type="entry name" value="Carb_kinase_FGGY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018485">
        <property type="entry name" value="Carb_kinase_FGGY_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018483">
        <property type="entry name" value="Carb_kinase_FGGY_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018484">
        <property type="entry name" value="Carb_kinase_FGGY_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005999">
        <property type="entry name" value="Glycerol_kin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02782">
        <property type="entry name" value="FGGY_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00370">
        <property type="entry name" value="FGGY_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000538">
        <property type="entry name" value="GlpK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01311">
        <property type="entry name" value="glycerol_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00445">
        <property type="entry name" value="FGGY_KINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 5" id="KW-0319">Glycerol metabolism</keyword>
    <keyword evidence="5 6 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FGGY_N" evidence="7">
        <location>
            <begin position="7"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="FGGY_C" evidence="8">
        <location>
            <begin position="260"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="84"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="244"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="14"/>
            <end position="16"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="14"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="18"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="266"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="309"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="313"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="410"/>
            <end position="414"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV57690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="498" mass="54341" checksum="603D7E7A67EC0D34" modified="2019-10-16" version="1">MKTTKFILALDQGTTSSRAILFDHSGQIRGVAQQEFRQILPQPGHVEHDPEEIWSSQLAVARQVMEEAKLTHDDIAAIGITNQRETVVVWDRETGKPIQNAIVWQSRITADLCDQLTRDGMADTFRNKTGLLIDPYFSGTKIKYILDRHPGLRARAQRGEVLFGTVDSFLLWRLTGGKHVTDYSNASRTLLYNIHDLDWDDELLTALDIPRAMLPEVLPSSGSFGETKAEFLGGVIPIAGVAGDQQAATFGQGCFEEGSAKNTYGTGCFMLMNIGETPKLSDNRLLTTIGWGIDGKVTYCLEGSVFVAGAIVQWLRDGLGIIAESSDVEALAAKVDGADDVIVVPALVGLGAPHWDPHARGAILGISRGTTAAHIARASIESMAFQTRDVLDAMQQDAGTKLKILKVDGGACCNDALMQFQADILDTAVQRPKVSETTALGAAYLAGLAVGYWKNLKAVKENWALDREFTPAMDPEIRESRYHKWQTAVERSKGWANS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXC2</accession>
    <name>A0A518IXC2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_37430</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002798">
        <property type="entry name" value="SpoIIM-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01944">
        <property type="entry name" value="SpoIIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="101"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="180"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="229"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="267"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="299"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="326" mass="35837" checksum="968D193FCC94ACF4" modified="2019-10-16" version="1">MNIVSLLEQRRHGWEELELLCNQMQNRGRTRAKAAGAARFASLYRSACADLALAEAYQLPPATVEYLHRLVGRAHNQLYRSRNFSLARSVDMLVRRAPQRIFADPCVHVCALLFFGLFWLSMLLGMSEQRLPDFPAQVVGQAQLEQMESNFEAELNAGFEHYVMMASFYIRHNTGIGLKCFAYGILIIPCIFTLAYNAVALGTSFGYMARDSTIGGENFFEFVTAHGPFELTAIVLSAAAGLRLGLGLISTTGLCRGDSLKVNAIRAIPVIAAAAVLFFLAAITEGFLSPSPLPYTFKAMWAIMSSGAMTFYFVVLGFPRAGIDAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXG4</accession>
    <name>A0A518IXG4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex</fullName>
            <ecNumber evidence="8">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">pdhC</name>
        <name evidence="12" type="ORF">Mal33_37980</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(R)-N(6)-dihydrolipoyl-L-lysyl-[protein] + acetyl-CoA = (R)-N(6)-(S(8)-acetyldihydrolipoyl)-L-lysyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:17017"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="Rhea" id="RHEA-COMP:10478"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="ChEBI" id="CHEBI:83111"/>
            <dbReference type="EC" id="2.3.1.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 8">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4">Forms a 24-polypeptide structural core with octahedral symmetry.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the 2-oxoacid dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="8"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045254">
        <property type="term" value="C:pyruvate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004742">
        <property type="term" value="F:dihydrolipoyllysine-residue acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003016">
        <property type="entry name" value="2-oxoA_DH_lipoyl-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001078">
        <property type="entry name" value="2-oxoacid_DH_actylTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006256">
        <property type="entry name" value="AcTrfase_Pyrv_DH_cplx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036625">
        <property type="entry name" value="E3-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004167">
        <property type="entry name" value="PSBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43178:SF2">
        <property type="entry name" value="PTHR43178:SF2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00198">
        <property type="entry name" value="2-oxoacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02817">
        <property type="entry name" value="E3_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47005">
        <property type="entry name" value="SSF47005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00189">
        <property type="entry name" value="LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51826">
        <property type="entry name" value="PSBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="5 8" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="12" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="10">
        <location>
            <begin position="2"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="Peripheral subunit-binding (PSBD)" evidence="11">
        <location>
            <begin position="159"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="84"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="201"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="127"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QDV57784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="465" mass="47807" checksum="D3B8140BFCCCA981" modified="2019-10-16" version="1">MATEVKLPELGDGIESGDVLEIFVSVGDVITAGQDVVEMETDKATVPVSSNAAGKVTKILVAEGDTVAVGGVILEIEAAAAAETPAASTPAEPAAEAPAKAPEPAAKAPETPAPAAASEKPAPAAPAPAAAEAPKPAPAAPAPAAPAAPAPASSDAIVAAGPAVRRFAREVGVDLQGVQGTGEGGRITREDVLAIVRSANQSRGGAATGTAAAPSKTAAAPVDAGAEQDEYGPIRVERMSKIRKTIASQMHESWSTVPRVTNFDDADISDLEHLRQSSKDDYAAQGLKLTTMPFLIKAIATALKHNPEVNAVIDEANGQLIYKDYVNIGIAVDTERGLVVPVMKNADRMGIPDIARSLAEMAAKVRSGQFAVSDLRGGTFTISNLGAIGGQYSTPIVNIPEVAILLVGRSRKLPCVMPDDSIKPRLMMPLSLSYDHRLVDGGTAARFLNDVIGYLEAPSRLLLAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYB7</accession>
    <name>A0A518IYB7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA (guanine-N(7)-)-methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.33</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">tRNA (guanine(46)-N(7))-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">tRNA(m7G46)-methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1 2" type="primary">trmB</name>
        <name evidence="2" type="ORF">Mal33_40990</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>guanosine(46) in tRNA + S-adenosyl-L-methionine = N(7)-methylguanosine(46) in tRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42708"/>
            <dbReference type="Rhea" id="RHEA-COMP:10188"/>
            <dbReference type="Rhea" id="RHEA-COMP:10189"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="ChEBI" id="CHEBI:74480"/>
            <dbReference type="EC" id="2.1.1.33"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">tRNA modification; N(7)-methylguanine-tRNA biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.33" evidence="1"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00989"/>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008176">
        <property type="term" value="F:tRNA (guanine-N7-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01057">
        <property type="entry name" value="tRNA_methyltr_TrmB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003358">
        <property type="entry name" value="tRNA_(Gua-N-7)_MeTrfase_Trmb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23417">
        <property type="entry name" value="PTHR23417"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02390">
        <property type="entry name" value="Methyltransf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00091">
        <property type="entry name" value="TIGR00091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51625">
        <property type="entry name" value="SAM_MT_TRMB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="1 2" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0819">tRNA processing</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="1">
        <location>
            <begin position="193"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="44"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="155"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="215" mass="24427" checksum="654B9EF160E05D78" modified="2019-10-16" version="1">MPRQQLRTPSTSIDLSQHFRMVDALPQQVTSQTLFQNDAGLQIEVGSGKGLFLLNASGEQPDQNFLGIEIAHKYAKHAATKLKNAGRTNAIMASGDALPIFEKQIPDASLAAVHVYFPDPWWKKKHKKRRVLNEPFLRSASRTLAPGGRFYFWTDVLDYFESTLELMAMVVPELGPPLPDVVSEAEHDLDYRTHFERRSRKNEIPVYRVHFDKPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYC6</accession>
    <name>A0A518IYC6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_41060</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011453">
        <property type="entry name" value="DUF1559"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07596">
        <property type="entry name" value="SBP_bac_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="306" mass="33137" checksum="7602AFE0951FCF14" modified="2019-10-16" version="1">MLRAKSLRKAFTLVELLVVIAIIGILVGLLLPAVQAAREAARRMQCGNNVKQITLATHNYHDTYNALPVGAYGCCWGTWQIAIQSFMEQDAIYEMYNQNGKFDIPDNSFRYSGAKNIAATSIRLDAHSCPSDMPNTPISTITSHNYAANYGNTGNAQQTVNGVLFEGAPYGTASSTNLKQYKFRDVLDGLSNTLMIAEVLQGKGGDLRGFTWWADATGFTTFLGPNTALPDRIYSSSYCQNLEVAGLPCAVSTTTNPTMFASRSRHPGGVQVGKCDGSVRFVAETVDLNAWRASSTTYGGEALQID</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYL9</accession>
    <name>A0A518IYL9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hydantoinase/oxoprolinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_41910</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002821">
        <property type="entry name" value="Hydantoinase_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002756">
        <property type="entry name" value="MfnF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01968">
        <property type="entry name" value="Hydantoinase_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03123">
        <property type="entry name" value="one_C_unchar_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hydantoinase_A" evidence="1">
        <location>
            <begin position="72"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="351" mass="37632" checksum="330EC1F835730BEE" modified="2019-10-16" version="1">MNDPTLANDAASQSAASDMRWIGIDVGGANIKAADTSGWTSAEPFALWKHPERLADQLRQQLPAPTATTRYALTMTGELADCFADRPQGVRQIVDAVAEATQTEASAGVDPLRVYSLDGQWLRADEAKSNPDDVAAANWHATASYAERYLGANETGLMIDIGSTTTDLITIDSNGVQTRSRTDFDRLLLSELLYLGVGRTPLCGLTSSLPFRGRDIPVMAEFFATTDDCFLVLGRTAAMPEDCDSADGKPRTVEHSVKRIARMIGLDHRSFNLDDAVAASEHIEAILKARVAAGIAKVASDASAWVIAGHGEWLLPKTVARQISLAQELGAERSRVGPAYALACLAEARFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYN0</accession>
    <name>A0A518IYN0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Acetyltransf_6 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_42120</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038740">
        <property type="entry name" value="BioF2-like_GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13480">
        <property type="entry name" value="Acetyltransf_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acetyltransf_6" evidence="2">
        <location>
            <begin position="193"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="390" mass="44190" checksum="0CA96C8575209336" modified="2019-10-16" version="1">MPLADSANQPTEVPETRRGDRGGAASGAGVCGSQRPSTCRTIPVRELDDGLVAAWKALRADNPALYSPFFSPEFTLAVDEVRDDGQIAIVERSGEPIAFLPFHRSGRSLFPIGRTINDAHGLICAHDTTIDWHWLLQQLDATGYEYHALFSSSDDAGEHAFGWTKAFLCDLTASDLRYDLWLEQNRKTIFKQRRKTKKLIRDEGPLRLEYASTDPAVLDRLIQLKREQYQRTRIFDIFSVDWIRNLLHLMLTRDGALQGRLSALYAGDKLVAMHMGMQEGKLLHYWFPVYDQAFGYASPGTALFLEIVRQAEANRIDKIDFGYGELPYKWTLNNVIDSVPHGAICVSHAAWHARRLRGGVMQTLKALPGKEWSKRVLRKVHPQFGRGRYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYN8</accession>
    <name>A0A518IYN8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase IS200 like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_42050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002686">
        <property type="entry name" value="Transposase_17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036515">
        <property type="entry name" value="Transposase_17_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01797">
        <property type="entry name" value="Y1_Tnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01321">
        <property type="entry name" value="Y1_Tnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143422">
        <property type="entry name" value="SSF143422"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Y1_Tnp" evidence="1">
        <location>
            <begin position="5"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="152" mass="17652" checksum="137D20D05BACA5E9" modified="2019-10-16" version="1">MSQSLAKVAIHFVFSTKHRKPLLDPLELREQLYAYMATILRENVDSPAIKIGGGEDHVHALLLLSRKFALADVAQEMKTETSKWLKKQATGLKAFSWQSGYGAFSVSESNIDDVKRYIANQQEHHRKMTFKEEFRELCRRHGLEIDERYVWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYQ0</accession>
    <name>A0A518IYQ0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 7">Citrate synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">gltA2</name>
        <name evidence="9" type="ORF">Mal33_42290</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>acetyl-CoA + H2O + oxaloacetate = citrate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16845"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16947"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.3.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Carbohydrate metabolism; tricarboxylic acid cycle; isocitrate from oxaloacetate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 5 8">Belongs to the citrate synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00223">
        <property type="reaction ID" value="UER00717"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004108">
        <property type="term" value="F:citrate (Si)-synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd06114">
        <property type="entry name" value="EcCS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016142">
        <property type="entry name" value="Citrate_synth-like_lrg_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016143">
        <property type="entry name" value="Citrate_synth-like_sm_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002020">
        <property type="entry name" value="Citrate_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019810">
        <property type="entry name" value="Citrate_synthase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024176">
        <property type="entry name" value="Citrate_synthase_bac-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036969">
        <property type="entry name" value="Citrate_synthase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010953">
        <property type="entry name" value="Citrate_synthase_typ-I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00285">
        <property type="entry name" value="Citrate_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001369">
        <property type="entry name" value="Citrate_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00143">
        <property type="entry name" value="CITRTSNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48256">
        <property type="entry name" value="SSF48256"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01798">
        <property type="entry name" value="cit_synth_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00480">
        <property type="entry name" value="CITRATE_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="active site" evidence="6">
        <location>
            <position position="316"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR001369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001369-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV58212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="438" mass="48927" checksum="5161B4C0DE17198B" modified="2019-10-16" version="1">MSTATNGEATTTGTARLSVGDTQIDMPVIEGTEHERAIDISKLRAETGLITIDEGFVNTGSTTSSICYLDGENGILRYRGYPIETLAENCDFVETSYLLIYGELPTADQLNEFRSSIRKHTMIHEDMRSFYNGFPRDAHPMAILSSVVGALSTFYQDSLDPHDAKEVEISIHRLLAKLPTIAAYSYKKSVGQPFPYPNNALTYCENFLEMMFGTPAEDYHPDPDFVKALNLLLIVHADHEQNCSTSTVRIVGSSNANLFASISAGICALWGPLHGGANEACVNMLQQIADDGGDVEKYVRMAKDKQDGFRLMGFGHRVYKNRDPRAIIIKEACDTLLAKMDIKDPLFDVAQRLEEVALQDPYFVERKLYPNVDFYSGVIYRAIGIPVQMFTVLFAMGRLPGWIAHWVEMHNSPGTRIGRPRQVYTGPTKRDFVPIENR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYX1</accession>
    <name>A0A518IYX1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Biopolymer transport protein ExbD/TolR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Mal33_42960</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the ExbD/TolR family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003400">
        <property type="entry name" value="ExbD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30558">
        <property type="entry name" value="PTHR30558"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02472">
        <property type="entry name" value="ExbD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV58278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="156" mass="16991" checksum="F7B521499166F672" modified="2019-10-16" version="1">MRLPSGHGREPLELKMTPMIDVVFLLLVFFLWTSSFEEPEYLMPSAIADPPLAAGAVATLQPPPASEPFDEIIVRIQWTSGAATLLFNDQPLPSLDALRQRLQAILDVGVLPPVIVDPDPEVPMGDAIRVYDTARSLGFDRVLFAARADTAPPSSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYZ2</accession>
    <name>A0A518IYZ2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_43240</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="QDV58306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021796">
        <property type="entry name" value="DUF3365"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11845">
        <property type="entry name" value="DUF3365"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="189" mass="21168" checksum="295BF9AD98D3839D" modified="2019-10-16" version="1">MLFRGWMIRACAFVLICVAVQVGRGDPPAAEKSEPETKVIPDAQRMPVAEARQRARLMHDIYAATLDVMHHRYFHGGRAIVPARAMEDIFEEIQRDSHTEARWISVNLKPMSIHHKPKTKFEQHAADEIAKGKPAVDIVEDGYYRRATAIPMSGGCIGCHDGFLKKPTKEAKFTGLVISIPVLEAKPEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ07</accession>
    <name>A0A518IZ07_9BACT</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
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    <organism evidence="1 2">
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1487" mass="170888" checksum="7773E0569C2A55AF" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ31</accession>
    <name>A0A518IZ31_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_43630</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="15"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="96" mass="10266" checksum="5527A45B0DB70C4C" modified="2019-10-16" version="1" precursor="true">MENIESGGLLPRFTLRWFSICFTLSVLIAWILRQAVMGSLWAQAGIATLVAMAGFFAIYAVLFLTIWIPTAIANLGSSSEQSTAAAAPSDPQEANS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZC5</accession>
    <name>A0A518IZC5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Vitamin K epoxide reductase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Mal33_44670</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the VKOR family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012932">
        <property type="entry name" value="VKOR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038354">
        <property type="entry name" value="VKOR_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07884">
        <property type="entry name" value="VKOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-0874">Quinone</keyword>
    <keyword evidence="9" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="30"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
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            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
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            <end position="135"/>
        </location>
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        <location>
            <begin position="141"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="domain" description="VKc" evidence="11">
        <location>
            <begin position="32"/>
            <end position="163"/>
        </location>
    </feature>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF07884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QDV58444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="211" mass="23600" checksum="05AB118DCFA72452" modified="2019-10-16" version="1">MFSKATVPCHDIERPVPPYKHNPSAWSQRIPICLLAFVAAGISVHLSLFQWGLIESVWDPVFGDGSDKVVKSDAALKMYGILGIHDAALGVLAYLGDAVLGLAGSARRWQYRPWLVVLFGIDVIPLGIVSVVLVAVQGLVVGSWCFLCLMTALISLILVYWAWDEVRVALTYLWIVWKQNRDRRLLWDAFWGNRSEPLDRAAESLLAREVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZG3</accession>
    <name>A0A518IZG3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_44940</name>
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    <organism evidence="2 3">
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        <lineage>
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            <taxon>Planctomycetia</taxon>
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    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="155"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="195"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="224"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="253"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="277" mass="29188" checksum="BB69056F4723B16A" modified="2019-10-16" version="1">MAIRLKCKCGKDLSLKDELAGKSIRCPGCKEVLKVPSGNAPPSRPAAAAPSQPTAFPAAAAAAPASGGVGSLFDDEGIGQLTGPVCMACAKEMRPGTLICMNCGYNTQTGERVQGFTESQVAASEFGHAALDEAAAHMRRDAKVQQQISGTGMPVWMLATILMCLGGLAVMGVFVSNAIAAEEGANSGSPVPRGMLLVILLFLQACSMYFWIKIMIHGFKESALHGFLSLFIGLYALIYAFRRPEIRTYGWSLLTISIIYSIVFFGGFALLGLLGLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZI6</accession>
    <name>A0A518IZI6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Flagellin N-methylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_45200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005358">
        <property type="entry name" value="Puta_zinc/iron-chelating_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03692">
        <property type="entry name" value="CxxCxxCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0966">Cell projection</keyword>
    <keyword evidence="1" id="KW-0969">Cilium</keyword>
    <keyword evidence="1" id="KW-0282">Flagellum</keyword>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="145" mass="17276" checksum="79032A419E631FFA" modified="2019-10-16" version="1">MTAPRPKRIPRELVPKGESLCDYCSAKCCRYFALPIDTPESRQDLDFIRWYLLHDRASMFVEGDTWYLLVHTTCKHLQEDHRCGIYETRPQICRDYTTAECEYEDTWVYDQYFETPEQVQDYMDALYGHEYESLRSRKPAALPIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZP2</accession>
    <name>A0A518IZP2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DDE_Tnp_1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_45770</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002559">
        <property type="entry name" value="Transposase_11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01609">
        <property type="entry name" value="DDE_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_1" evidence="2">
        <location>
            <begin position="165"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="423"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="440"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="460" mass="51213" checksum="253A72389FEA1508" modified="2019-10-16" version="1">MTVDELLDRFKNECPVAMGTRLVLNHLLSDERMDTLFATHAGSQRCGELLFSSVADIMACVALNIKPSVNAAYKKHKEKLKVSVTSVYNKLQGIETQVSRALVSETAAELSQLWDHLEGPKPPPVLSGYKTRIIDGNHLAGTEHRIKELRTLGAAALPGTTIPILDPDKKLLVDVILSRDGHANEATLHPEILELVEKGEVWIGDRYFASQKMMTTIALDKKAFFVFRHSKGLLPNWESQGERRRIGRCDGGTIYEQKIAFTYQGRAICPRRVTIELDTPTRKGDTAVHVLTNLPSRVSAKSVANAYLKRWNIETAFQHLATTLNSEINTLGYPQAALFSFCMSMMMYNLISVMKTSIGCAAGDADLADEVSSYYAANDVSESWKGFMTAVTEKEFDSVYGKLTLKQLAKELVDVARKLDFSQYRKSHRGPKKPPPKRKSGNRGNHESTARILDQRAPKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZQ4</accession>
    <name>A0A518IZQ4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Arginine--tRNA ligase</fullName>
            <ecNumber evidence="9">6.1.1.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Arginyl-tRNA synthetase</fullName>
            <shortName evidence="9">ArgRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9 14" type="primary">argS</name>
        <name evidence="14" type="ORF">Mal33_45990</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg)</text>
            <dbReference type="Rhea" id="RHEA:20301"/>
            <dbReference type="Rhea" id="RHEA-COMP:9658"/>
            <dbReference type="Rhea" id="RHEA-COMP:9673"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32682"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78513"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.19"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="9">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9 10">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.19" evidence="9"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004814">
        <property type="term" value="F:arginine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006420">
        <property type="term" value="P:arginyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00123">
        <property type="entry name" value="Arg_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001278">
        <property type="entry name" value="Arg-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005148">
        <property type="entry name" value="Arg-tRNA-synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036695">
        <property type="entry name" value="Arg-tRNA-synth_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035684">
        <property type="entry name" value="ArgRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008909">
        <property type="entry name" value="DALR_anticod-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11956">
        <property type="entry name" value="PTHR11956"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03485">
        <property type="entry name" value="Arg_tRNA_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05746">
        <property type="entry name" value="DALR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00750">
        <property type="entry name" value="tRNA-synt_1d"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01038">
        <property type="entry name" value="TRNASYNTHARG"/>
    </dbReference>
    <dbReference type="SMART" id="SM01016">
        <property type="entry name" value="Arg_tRNA_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00836">
        <property type="entry name" value="DALR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55190">
        <property type="entry name" value="SSF55190"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00456">
        <property type="entry name" value="argS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 9 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arg_tRNA_synt_N" evidence="13">
        <location>
            <begin position="5"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="DALR_1" evidence="12">
        <location>
            <begin position="539"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="244"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="9">
        <location>
            <begin position="124"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM01016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="QDV58576.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="658" mass="72574" checksum="7BAEA321B2D5665A" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
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    <name>A0A518IZV8_9BACT</name>
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        <submittedName>
            <fullName evidence="3">YCII-related domain protein</fullName>
        </submittedName>
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        <name evidence="3" type="ORF">Mal33_46500</name>
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    <organism evidence="3 4">
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        <lineage>
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    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
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                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 4">Mal33</strain>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <location>
            <begin position="1"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="127" mass="13866" checksum="50CE714F4422B712" modified="2019-10-16" version="1">MKFVCLGYIDETRFADLTQAQRDETMEACFAYDDELRRGGHFIGGEALQSARNAVTLRIKEGKVDVTDGPYAETKEVLGGILLLEANDLNHAIALMSQHPGVTVGPFEIRPADAQINAMIAARQTNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
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    <name>A0A518J041_9BACT</name>
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            <authorList>
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                <person name="Boedeker C."/>
                <person name="Pinto D."/>
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                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
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                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
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                <person name="Mascher T."/>
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                <person name="Devos D.P."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="56" mass="6798" checksum="C10DB54DE9B293E5" modified="2019-10-16" version="1">MTEFHGKALEYTLELELHLFFIPLMQDWGDGIVMTRTLQLPLRRDRSRRVCHLKRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J066</accession>
    <name>A0A518J066_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">Mal33_47530</name>
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    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
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                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
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                <person name="Jetten M.S.M."/>
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                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">Mal33</strain>
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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            <end position="246"/>
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    </feature>
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        <location>
            <begin position="216"/>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="284" mass="32177" checksum="9A2113B964535AC7" modified="2019-10-16" version="1">MRHFTDQRLRYFVNQSSPVCVGSHSKRTCLADRNKTEVLIPRSPVPTFRKDAQCLEDHSPLRQLLALLRLDACCFPDAANREPATTVAAPLLRPAMDRLRNHNPPIRVLARVIRRYRLQLPPQRKTTHLRAVRAHVLHHLAARAHVRRSRNRIAGAILEASEWQPIRQHKRLQKVSLNCVSIARVHRLLLRSASRFRRDADTICIRNEVGPMETELSSDRDQQVAGASVKQQHAASHQPVAPTQRWRLERPSHVLAAMPEAITEGDFGCGASCQEAVDRIGVAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J069</accession>
    <name>A0A518J069_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ferredoxin--NADP reductase</fullName>
            <ecNumber evidence="6">1.18.1.2</ecNumber>
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    <organism evidence="6 7">
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            <taxon>Planctomycetes</taxon>
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    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
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    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12801">
        <property type="entry name" value="Fer4_5"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
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            <end position="363"/>
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    <feature type="transmembrane region" description="Helical" evidence="4">
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        </location>
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    <feature type="transmembrane region" description="Helical" evidence="4">
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    <feature type="transmembrane region" description="Helical" evidence="4">
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    <feature type="transmembrane region" description="Helical" evidence="4">
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="641"/>
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    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
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            <end position="687"/>
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        <location>
            <begin position="745"/>
            <end position="774"/>
        </location>
    </feature>
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        <source>
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        <source>
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        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
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    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
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        <source>
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    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV58730.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
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    </evidence>
    <sequence length="801" mass="88071" checksum="7F03146409682884" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J073</accession>
    <name>A0A518J073_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">FAD-dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_47680</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="524" mass="54905" checksum="DC3DC4D36390A0F7" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0A0</accession>
    <name>A0A518J0A0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Peptidoglycan O-acetyltransferase</fullName>
            <ecNumber evidence="11">2.3.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">patA_2</name>
        <name evidence="11" type="ORF">Mal33_47980</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the membrane-bound acyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="11"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042121">
        <property type="term" value="P:alginic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024194">
        <property type="entry name" value="Ac/AlaTfrase_AlgI/DltB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028362">
        <property type="entry name" value="AlgI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004299">
        <property type="entry name" value="MBOAT_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03062">
        <property type="entry name" value="MBOAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500217">
        <property type="entry name" value="AlgI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016636">
        <property type="entry name" value="AlgI_DltB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 11" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="48"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="76"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="114"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="150"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR016636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QDV58773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="484" mass="54924" checksum="6010FFAABC783CEC" modified="2019-10-16" version="1">MLFNSFAFLIFLPCFLAIYWTLRGRGRIAFCLAGSYLFYGWWDARFLGLLILSSVVDFTVGLALGKTDSPSRRRLLLSLSIVSNLGILATFKYFNFFADSLQQLVAPLNWSLDWPTLNLILPAGISFYTFQTLSYSIDVYRKQILPQRDFLRFATFVGFFPQLVAGPIVRAGEFFPQLETDRRFAWEDFESGFGRVLQGFFKKIVIADSIGTVVDPMFRDPEGFSSLNTAMIVVLYAFQVYCDFSGYSDIAIGTARMLGIRLPENFRTPYLATSPADFWHRWHISLSTWLRDYVYIPLGGSRRGAWKTYRNLAITMLLGGLWHGASWNFVIWGAIHAGLLIAHRIWISFLGPPSTRLADCETFSAAWLQRLGIDAAKSAMMFTALCITWVFFRSGSFDQAVQILAQIASLDGLSPSTLQNRIPLLKACGLVSILAGFEIASHFIRWPQLFLRIPAARAVYYACLLWSLALWGTFDGKQFIYFQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0B6</accession>
    <name>A0A518J0B6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Epimerase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_48060</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013549">
        <property type="entry name" value="DUF1731"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010099">
        <property type="entry name" value="SDR39U1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08338">
        <property type="entry name" value="DUF1731"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01777">
        <property type="entry name" value="yfcH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="2">
        <location>
            <begin position="163"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1731" evidence="3">
        <location>
            <begin position="412"/>
            <end position="459"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV58781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="462" mass="50321" checksum="B8A6A9E9524A822D" modified="2019-10-16" version="1">MANKRYLRCVDLPGTIDQAFAYHDRPGALMRLIPPWESVTILRSDNSLQPGSEVELKTKLGPLSIRWLARHELYHPPRLFSDIQVSGPFAYWHHAHRFETGADPESSRMCDTVDYRLPGGAIGAVLGAGKALRTLDAMFAYRHRTTRDDLQMFVDHDPEPLRIAVSGSTGLVGSCFNNVASLLGHDIVRLLRGEPTSDDASAADAGIYPWSDSFAPESFAGTDAVVHLAGKPIADKRWTPEIKQQIIDSRVTQTRALCEHLAAMQTPPKVLICASAIGIYGDRGDEILSEESEIGEGFLADVGRQWEAACKPAEEAGIRVVNLRIGLALSPQGGALQQLLLPAKLGVNGPVSHGKQWWSWVALDDVIGAIYHAIKTPTLRGPVNVVAPNSVTCGQFARDLGRVLHRPAFIPAPAPILRLALGEMADALLLASTHVVPGKLQASGYRFRFEDLTTCLRHLLGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0E5</accession>
    <name>A0A518J0E5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Thioredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">trxA_7</name>
        <name evidence="2" type="ORF">Mal33_48410</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="1">
        <location>
            <begin position="9"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="293" mass="31557" checksum="48A2A67FBB6EF442" modified="2019-10-16" version="1">MASSGAIWQNGGMNNPTLIETTDATFELDVLERSRTVPVVVDFWADWCQPCRMLAPILEKLAEEFAGSVIVAKANTDDCQQAASEFGVSGIPALFGVVDGTIVDGLQGAVSEEVLRVFFRRMVSAAEFRTAMQIEDTDPAAALATYDKMLEDDPENLPAKIGRGRASLAAGDVATATQILEELEARGFLEPEAEQLKSRLSLAASVPAGDLQELEKQLAADPSNSPLKIEVARKQAAAGSFQAALDLALEVVEATHGDDRDQARLLMIDIFRTLPDDSPLTGEYRRKLASALY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0H7</accession>
    <name>A0A518J0H7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Choloylglycine hydrolase</fullName>
            <ecNumber evidence="5">3.5.1.24</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">cbh</name>
        <name evidence="5" type="ORF">Mal33_48690</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C59 family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.24" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045302">
        <property type="term" value="F:choloylglycine hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029132">
        <property type="entry name" value="CBAH/NAAA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02275">
        <property type="entry name" value="CBAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021953146" evidence="3">
        <location>
            <begin position="27"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="domain" description="CBAH" evidence="4">
        <location>
            <begin position="27"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV58844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="364" mass="38920" checksum="2FD0AC6BB79AC5AC" modified="2019-10-16" version="1" precursor="true">MKSFWNITACCALVALSILSASPAPACTGITLSPKDGSVIFARTLEFATDLKSNVIVVPRGKEYVGTAPGNQPGLRWTTKYGTIGANAVDLPYIIDGINEKGLHVGLFYFPGFAKYQTVEKQDFDKSLAPWEFGTYLLGTCANADEAVAAAGKVLVGDAVQKEMGIVPPAHFIVSDAAGNCFVLEHVDGELKVHQNPFGVITNSPAFDWHVTNLSNYMTLSPENKPNIDLAGKQIGSLGQGSGMLGLPGDFTPPSRFVRAVAYSQTALQSADAKSGVLQAFHILNAFDIPVGAAAGIEGGHRVFDRTLWTSVADLKNVRFYFRTLENSQIRMVDITKVDLDAAEVQSISMGGEEQIEDLSATAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J131</accession>
    <name>A0A518J131_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_50740</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="193" mass="21661" checksum="57AF791756670500" modified="2019-10-16" version="1">MHRSGGGQPNENLQSFAAAPVMPAVLPLKMLNRLITKFNDVMEHLVDAVRLRLIGPHLLGDIPQIPLPCKLDDALKAYGEPYEQSEGDVLPDTQNYTFEVHDLHLVQIWVWKSEVHQILYTSPRGDGATDLQTVFDAYGDGKEWTTWTEGYLYASADDSLRVWCSALPMIGVGTKEFVHFRDAHKSAAKEQDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J173</accession>
    <name>A0A518J173_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_51180</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010869">
        <property type="entry name" value="DUF1501"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07394">
        <property type="entry name" value="DUF1501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="482" mass="53371" checksum="7895049A02F22DBE" modified="2019-10-16" version="1">MTTTFTDATSVNRRLFFRRGAAGIGVAALANLLKENAHAAVDQADPQLESEGLHFAPKAKRIIYLCQSGGPAQHDLFDYKPLLNQRNGSELPASIRGQQRLTGMSANQSSLPLAGSQFKFAQHGQSGAWLSELLPYHREIVDDVCFVKSMYTEAINHDPAITFFQTGSQIAGRPSLGAWMSYGLGSENKDLPSFIVLVSSNQGGQPLYGRLWGSGFLDSRHQGIQFRGGADPVLYLSNPKGVSSSRRRAQLDVIGQLNRHQFQRELDPEIESRIAQYEMAYRMQTSVPDAANFADEPESTFKAYGEDARTPGTFAANCLLARRLAQRDVRFIQVYHQGWDQHSNLPKQIAGQAKETDQASAALVKDLKQCGLLKDTLVIWGGEFGRTPYSQGTLKPGNYGRDHHPRCFTTWMAGGGIKPGISYGATDEFGYNITEKGVHVHDFNATILHLMGIDHERLTFKYQGRRFRLTDVHGHVVNEIVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J182</accession>
    <name>A0A518J182_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_51250</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010869">
        <property type="entry name" value="DUF1501"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07394">
        <property type="entry name" value="DUF1501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="468" mass="51293" checksum="BC5749E8C74073D1" modified="2019-10-16" version="1">MKPMFGRRELLRRTAGGLGSIALAAMLAEEGSAATHAAANDPLAAKVPHFPAKAKRVILLYMTGGVSHVDSFDPKPELYAGHGKKITVDNWQGKIGEFPRFLKRPDWQFRPGGESGTEVSDLFPKTREIVDELCVIRSMSTDHTNHYESTLGMHCGSWTFARPSLGAWISYGLGTVNRNLPSFVVVAPQAPYAGAQTWGSDFLPGSHKGTQFIPGDTPIPNIQPRVGSAELQKMELELLAQANRRHAEERPDEAVLDARIRSFETAFGMQQEAPEALDLSTESAATLQAYGLQPGQKSGFGWQCLVARRLAERGVRFIELIDVGSSNNWDAHGDMQTHLPLAKNVDGPIAALITDLKQRGMLDDTLVVWTTEFGRTPYHETANHAGREHHHQVFSSWLAGGGVKGGIVHGASDDLGIAVDSDRVHVHDFHATILHLLGLDHEQLTFRHAGRDYRLTDVHGNVVREILS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1J7</accession>
    <name>A0A518J1J7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Methyltransf_11 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_52420</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="1">
        <location>
            <begin position="99"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="271" mass="31059" checksum="C72BBC92B411860B" modified="2019-10-16" version="1">MPLMATQPCTGHMPHRHRIQFPPHDANNLEQDEVTFHVVEGERRLELRFHDYDQIYLRPGLYEQVFYDRLKCTSPKKVGELLKRTLDGSEKNFTEMRVLDLGAGNGMMGELLKSYGVARLVGADIIPEAKDACYRDRPGVYDEYYVADFTNLKPELVEEISDWSIDCLTSVAALGFGDIPPEAFFQSLQFVAKGGWVAFNIKETFLDRSDTSGFSRFIRELIFSKYLDIHHIERYRHRLSMEGTPLYYFALVAQKTADIPNDFLQANGIGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J255</accession>
    <name>A0A518J255_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_54600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="19"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="99" mass="9896" checksum="AF7FF98781611AB5" modified="2019-10-16" version="1">MVEVEGATKLGQLPLLSRIVMFVASLSLSVIGLTVSNLRSGATGSGKRIGLGASNPVDRHSLTTAPPGCGGGFCKSLQQLEPLAAGSVGCERGMGWGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J259</accession>
    <name>A0A518J259_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_54460</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007367">
        <property type="entry name" value="DUF433"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04255">
        <property type="entry name" value="DUF433"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="76" mass="8367" checksum="7A0480FA77E042A7" modified="2019-10-16" version="1">MFDRIVCDPEILSGKPTVKGTRISVEIILEWLASGATPEEIVSEYDHLSIEDVQQALRYAAAALHDNLVIQTKVAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J288</accession>
    <name>A0A518J288_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_54880</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="13"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="49"/>
            <end position="56"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV59453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="257" mass="27381" checksum="A3291B90AC6C1D7A" modified="2019-10-16" version="1">MLQTKSSSQAIPLDVQQVVKKYPQGGSVVHALDGVSLSVEPGEFVAIMGASGSGKSTLLHAMAGLIDVDAGRVLVAGQDLSQLADGPLTRFRRDNLGIVFQAYNLIPSLSAEDNIRLPAPKSLGKQLDATVDELFDRLGMTARRHHKPGALSGGEQQRIAIARALICNPTILLADEPTGSLDSVTGTQICELLRDLVDNQGRSIVMVTHEPHVAMWADRICVLKDGTNLAELQTDGSRDPQTVAQQYQEALGAETVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ILU6</accession>
    <name>A0A518ILU6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Beta sliding clamp</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">dnaN</name>
        <name evidence="13" type="ORF">Mal33_00020</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Forms a ring-shaped head-to-tail homodimer around DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the beta sliding clamp family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009360">
        <property type="term" value="C:DNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00140">
        <property type="entry name" value="beta_clamp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001001">
        <property type="entry name" value="DNA_polIII_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022635">
        <property type="entry name" value="DNA_polIII_beta_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022637">
        <property type="entry name" value="DNA_polIII_beta_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022634">
        <property type="entry name" value="DNA_polIII_beta_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30478">
        <property type="entry name" value="PTHR30478"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00712">
        <property type="entry name" value="DNA_pol3_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02767">
        <property type="entry name" value="DNA_pol3_beta_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02768">
        <property type="entry name" value="DNA_pol3_beta_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000804">
        <property type="entry name" value="DNA_pol_III_b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00480">
        <property type="entry name" value="POL3Bc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00663">
        <property type="entry name" value="dnan"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7 9" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="5 9 13" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DNA_pol3_beta" evidence="10">
        <location>
            <begin position="1"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="DNA_pol3_beta_2" evidence="11">
        <location>
            <begin position="129"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="DNA_pol3_beta_3" evidence="12">
        <location>
            <begin position="248"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR000804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="QDV54061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="371" mass="40782" checksum="5EE473DE6DACF189" modified="2019-10-16" version="1">MKITCERETFAAAFQLAAGVAPSRSPKAILQNVKIIARDGAVTLSATDMEVGIHLNVDGVEIETDGTALLPVQRVSSILRESSDEHLTFEASETGIKVRGSRSRFQLPGANPDEFPSVATFQETSYHEIATRLFRELVRRTVFATDAESGRYALGGVLLEMEGERVTAVGTDGRRLATMTGTGVSIGEHKTSGTNTIVPNRSISLIERALNDKDETVEVAARSNDLLVRTPRCTIYSRLVEGRYPNWRQVLPQRDDVVTIDLTIGPLHAALRQAAIVTDHESRGIDFTFGEGTMLLEANTAEVGESRVEMPIGYEGEPIKVTLDHRFLADFCKVLDAERTVQMEIESSDRPALLTTDDGFQYVVMPMARDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IM19</accession>
    <name>A0A518IM19_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_00710</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="344" mass="38355" checksum="EAE28BB9DC835C39" modified="2019-10-16" version="1">MSESELPPVLEELASINMAYSYLGSEKDFRNVEDEKNCFCRHAAGLLLLSEHDNTIGNQLQSRIQGKITDAKREFLRLASDIESSVDPDKPRPNNFNFAAVRDTHRRKAEQIVEKFLSETLTARTILRVNEFESQCNPATVANITRDMRRRSAELERSIEEARQGTEKIEAMLADLGDKIEKKTIEDAADDFKKLASGHRSHECFWSVSLVITAIGFCLAIFKSYTSIGDLAGDSVQHVGGVTAAIAGTRNLLLLSLAGIGMRISLTKYNVERNMRVIYDHRETALSQYNLLKDRLDGDAEAQRQLLLEVTRLLFSDPATGLTKLPDEVNVNPVLNVVSKALGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IM24</accession>
    <name>A0A518IM24_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_00770</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="22"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="155"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="190"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="240" mass="27286" checksum="45C334641D6CBA1D" modified="2019-10-16" version="1">MIPDYPDQTNVLVVSYLTIRRAIGVSGLLLPLVLGPGGWLFGIPFQHNISSYYHTGMRDIFVGTLCAIGIFLYCYRGYDWIENWTANLGCASALGVALFPLDFNSDPLVQKSLTGYLHTFSGGVFFLTLAFYSLYHFPRDSHREAEPHLQERRWIYRASGIVILISLVTMGGFLFVLNSQWKQTLNDYNFLFWMEWIAIWAFAAAWLAKGRTIIADIAVDVLAYANQLIPKRRTGNDRPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IM80</accession>
    <name>A0A518IM80_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF4886 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_01360</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032616">
        <property type="entry name" value="DUF4886"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16227">
        <property type="entry name" value="DUF4886"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022185124" description="DUF4886 domain-containing protein" evidence="2">
        <location>
            <begin position="25"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4886" evidence="3">
        <location>
            <begin position="36"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="590"/>
            <end position="613"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV54187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="650" mass="72027" checksum="48EB44FF8338A413" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMH8</accession>
    <name>A0A518IMH8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_02480</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="124" mass="13773" checksum="673E6B5B76B1F091" modified="2019-10-16" version="1">MDYQPSDGTWQVGGDARLLIELRQQMTTDQYESNKQALKEFLCGYFSSGDCNRALGDSISPLKATAKGGKVLKVRWALPGSGKSGSLRLVVVAYCHEKRVHIAQAFNRRDNPSGDDFREAVDDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMM1</accession>
    <name>A0A518IMM1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Aldose 1-epimerase</fullName>
            <ecNumber evidence="3">5.1.3.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">mro_1</name>
        <name evidence="8" type="ORF">Mal33_02930</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>alpha-D-glucose = beta-D-glucose</text>
            <dbReference type="Rhea" id="RHEA:10264"/>
            <dbReference type="ChEBI" id="CHEBI:15903"/>
            <dbReference type="ChEBI" id="CHEBI:17925"/>
            <dbReference type="EC" id="5.1.3.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 3">Carbohydrate metabolism; hexose metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the aldose epimerase family.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.3" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00242"/>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004034">
        <property type="term" value="F:aldose 1-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019318">
        <property type="term" value="P:hexose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015443">
        <property type="entry name" value="Aldose_1-epimerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008183">
        <property type="entry name" value="Aldose_1/G6P_1-epimerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01263">
        <property type="entry name" value="Aldose_epim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005096">
        <property type="entry name" value="GALM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="SSF74650"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021981661" description="Aldose 1-epimerase" evidence="7">
        <location>
            <begin position="26"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="99"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="197"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="197"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="336"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="269"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR005096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR005096-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR005096-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR005096-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV54340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="371" mass="40986" checksum="6363D752232114D4" modified="2019-10-16" version="1" precursor="true">MKPSPLKSLFLIAAAALLLANPAAAVEVDDFDSIQLYTLKNRSGMTVSVTNYGAIITSIVVPDRNGKMADVALGYDRVEDYINAVDRPYFGAIVGRYGNRIANGKFTLDGKTYSLATNNNPNHLHGGNIGFDKVVWDAKPIEGQNAIQLSYLARDKEEGYPGNLQIRVTYTLTDDNAILVDYHATTDQATPVNLTQHTYFNLKGEGEGTILDHELMLNADRYTPVDATAIPTGELPAVAGTPMDFTQPKPIGRDIDQENQQLEFGRGFDHNWVLNKPDDNKAMTLAARVYEPTSGRVMEVHTTEPGIQFYCGNFLDGRLIGKAGKPYVHRGGFCLETQHYPDSPNQPDFPSTILRPGKTYQTQTSYRFSTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMX2</accession>
    <name>A0A518IMX2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Calcineurin-like phosphoesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_03990</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos" evidence="1">
        <location>
            <begin position="69"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="379" mass="43029" checksum="4DF93CE57BA30A7A" modified="2019-10-16" version="1">MWFENDQTACRIFIDTPPHSKSNEPLLISSHKKLSFPLLLLALTFHLGTFTSSADAQERTLPAADADSFSIVVIPDTQLYRPKDGKLSNDIFTQHIDWTLANLEKQNIVFVSHVGDIIDRNIDEQWIVAQQCMNRLHDKVPYGISVGNHDMTRAGDSSLFQKYFPTERFANCDWYGGCYTPKTHGVEVSGNNANSFQLFSTAGIDFVFLHLECNAPDDVLAWADEVLTQHNDRRAIITTHMCLGPKHHPKMPSDYMDAPKGRMQWKKVHGKLGNTPEEMWQKCFRKHANLSMICCGDQSRSHSLHEVAVGDHGNQVHQVLSDYSTGWLRLYRFHPAKNRVEAWTFHPSNEELCEGTKHVPGADGHQFAFDFPLTESKLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMZ3</accession>
    <name>A0A518IMZ3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Nitrogen regulation protein NR(I)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">glnG_1</name>
        <name evidence="4" type="ORF">Mal33_04130</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002197">
        <property type="entry name" value="HTH_Fis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02954">
        <property type="entry name" value="HTH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="7"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="122"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="122"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV54459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="224" mass="24245" checksum="B44E2D7A7040DAB6" modified="2019-10-16" version="1">MTAAPFNVLVVDDEPGIRIGLARGLFGEADLVATAADANEALELFGKEAFHFVIIDFNLRSGLSGLELLQQFHKLQPGADAIVITAYGSVDVAVQAMRAGALDFVPKPLDLNDVRQRVRSARMKHRLESESNRVPKAPDDGPPNEVDGDVGEQLPSPSLLQASRGLSAASGPLPNSLAEAVQECERMTINRALQACGRHREKTAKALKISVRTLHYKMGRYSLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IN04</accession>
    <name>A0A518IN04_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Histidinol-phosphate aminotransferase</fullName>
            <ecNumber evidence="3">2.6.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Imidazole acetol-phosphate transaminase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 5" type="primary">hisC</name>
        <name evidence="5" type="ORF">Mal33_04220</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>2-oxoglutarate + L-histidinol phosphate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:23744"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57766"/>
            <dbReference type="ChEBI" id="CHEBI:57980"/>
            <dbReference type="EC" id="2.6.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 3">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 7/9.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.9" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00012"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004400">
        <property type="term" value="F:histidinol-phosphate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01023">
        <property type="entry name" value="HisC_aminotrans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001917">
        <property type="entry name" value="Aminotrans_II_pyridoxalP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005861">
        <property type="entry name" value="HisP_aminotrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01141">
        <property type="entry name" value="hisC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00599">
        <property type="entry name" value="AA_TRANSFER_CLASS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2 3 5" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="3" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="4">
        <location>
            <begin position="28"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="3">
        <location>
            <position position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV54468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="357" mass="38987" checksum="5F15A811F83908A9" modified="2019-10-16" version="1">MTNSKLRFRPALSKMKAYVPGEQPQGGKFIKLNTNENPYPPAPAVVEAIRAAADSRLERYPDPVGSSFRRMAAQRLGLPGPEWILCGNGSDEILTILVRGFLSDGDLLRMPTPSYILYRTLAEIQGARCEEISFNADWTLPAAFSSSDGDPRLALLPNPNSPSGTVLSPQAVAEIAAPLPCPLVVDEAYGDFAEENCIELVKQHENILVTRTLSKSYSLAGLRFGFLVAQPHVIAELTKIKDSYNCDAIAIAAATAAIAASDWQTENRAKILATRERAKGKLRELGFDVLDSAANFLWCTHPDRALKPIYEALKENQVLVRYMDYADWGDGLRITIGTDAQIDAALVVLARLLQSDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IN54</accession>
    <name>A0A518IN54_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MMPL family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Mal33_04740</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004869">
        <property type="entry name" value="MMPL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000731">
        <property type="entry name" value="SSD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03176">
        <property type="entry name" value="MMPL"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50156">
        <property type="entry name" value="SSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="16"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="241"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="269"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="313"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="344"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="401"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="596"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="636"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="664"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="700"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="735"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="domain" description="SSD" evidence="7">
        <location>
            <begin position="649"/>
            <end position="762"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV54519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="769" mass="82380" checksum="AF850D1747E87E01" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IN56</accession>
    <name>A0A518IN56_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Serine/threonine-protein kinase PknB</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">pknB_3</name>
        <name evidence="2" type="ORF">Mal33_04780</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
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        </citation>
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            <strain evidence="2 3">Mal33</strain>
        </source>
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    </dbReference>
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    <keyword evidence="2" id="KW-0418">Kinase</keyword>
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        <location>
            <begin position="11"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="300" mass="34286" checksum="E26080D0F4FD4AF9" modified="2019-10-16" version="1">MAKMRDSLGPYRLVRLIRNGATSQIWEAVEDASDNRVAIKLLKDNFKDDKEEIASLKNEFEVASSMNSPLVLKAFHHGVENGIPHNVFELASETSFRNLVRMGVDAYGFMLQKMIQKSAEGLYYMHTKDWIHRDIKPDNFLVTRDGDVKLIDYRIAEKKRTGLKAMFYKPKVQGTRSYMSPEQIRAKGIDERSDMYSYGCTLFELVTGKPPYTATSPTELLNKHLTGQVVSPLAGNPNVSPEFSELIKKMMAKKKESRPASMWEFLKELRAITLFKKSPRIPDVHPFDQLEKGEKGFNLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IN61</accession>
    <name>A0A518IN61_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_04680</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="81" mass="9070" checksum="E09D89054D1C9E84" modified="2019-10-16" version="1">MQSTTLSPPAGPTNTFVDRRSAPNPNASVSERRQFVSSHDGLSDEAKELALAIDSYKLQHRRRYITFEEMLSVVKGLGYSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IN93</accession>
    <name>A0A518IN93_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">C4-dicarboxylic acid transporter DauA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">dauA_1</name>
        <name evidence="7" type="ORF">Mal33_05230</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008271">
        <property type="term" value="F:secondary active sulfate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011322">
        <property type="entry name" value="N-reg_PII-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015867">
        <property type="entry name" value="N-reg_PII/ATP_PRibTrfase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011547">
        <property type="entry name" value="SLC26A/SulP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001902">
        <property type="entry name" value="SLC26A/SulP_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11814">
        <property type="entry name" value="PTHR11814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00916">
        <property type="entry name" value="Sulfate_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54913">
        <property type="entry name" value="SSF54913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
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            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
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            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
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            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
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            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
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            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
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            <end position="301"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
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            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
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            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="415"/>
            <end position="438"/>
        </location>
    </feature>
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        <location>
            <begin position="23"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV54568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="678" mass="73757" checksum="FC3FD0C5CE321D5E" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INK2</accession>
    <name>A0A518INK2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Radical SAM superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Mal33_06150</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040086">
        <property type="entry name" value="MJ0683-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43432">
        <property type="entry name" value="PTHR43432"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01084">
        <property type="entry name" value="Uncharacterised_Radical_SAM_Su"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Elp3" evidence="7">
        <location>
            <begin position="64"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="334"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="337"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV54660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="355" mass="40612" checksum="67D8E593173B68E5" modified="2019-10-16" version="1">MQPMRHGSELDPPNRFESVRRELELEQLEWDQEHLASHDRREIEYLPDDSKSIVSENKSPDIPFRYSVNPYRGCVHGCSYCYARNTHEFLGFNAGLDFETKIMVKHKAPQLLETFLNRKSYQPETISFSGVTDCYQPAERQFRLTRQCLEVALRYQQPVGIVSKNALVVRDLDLLQLLAAQNLVHVYLSITTLQPELARAMEPRTSIPTARLRAVRMLAEAGVPVGVMVAPVIPGLNDSEIPAILDQARQAGAATANFILLRLPLTVEPVFREWLQRTQPEKQELIEARVRQTRDGSMYDSQWNQRMRGSGTIAEQIKQMFQLFAKKHGLDKPLPQVDSSRFQNPNAGPQQMNLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INL6</accession>
    <name>A0A518INL6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Vault protein inter-alpha-trypsin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_06300</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="MprA_tail"/>
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        <property type="entry name" value="VIT"/>
    </dbReference>
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        <property type="entry name" value="VWF_A"/>
    </dbReference>
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        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08487">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="VWA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="VIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="VIT"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VIT" evidence="3">
        <location>
            <begin position="54"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="2">
        <location>
            <begin position="308"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="652"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="658"/>
            <end position="687"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV54675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="738" mass="81206" checksum="D0CDA8F400D9B463" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP72</accession>
    <name>A0A518IP72_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF1570 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_08510</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011464">
        <property type="entry name" value="DUF1570"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07607">
        <property type="entry name" value="DUF1570"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1570" evidence="1">
        <location>
            <begin position="215"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="377" mass="42814" checksum="48B18007E84A14A2" modified="2019-10-16" version="1">MLRNRNLNVWTLLGVTWMLIFTTLTAGKVVAADHVTFVQGGQTLKVCGEALLEAQDGGLLFQANDGQIWTIQPEEIKDRKQDSMPVEIPSPEVAVAELVATLGSEFRVMQTAHYVVVSNADAPFVEYCAGLFEKLYKGFYAFWKNNGWDLPEPRFPLVALVFEDKASFQRYARPEAGDAAESIIGYYNLQTNRMTTYDIGEGAGVRAGGFLVDRNIATLVHEATHQLAYNCGLQKRYADNPYWVSEGMAVFFESPDLKRGDGWREIGRINEVNRLRFAQYLPQRPADSLVTLLQDDSRLTNSATASFAYAEAWALTYFLLKTKPKQYVAYLKQLSEGEYLESLGPRERLQMFRDAFGDLQKLDRQFIAYTRRFVLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP84</accession>
    <name>A0A518IP84_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Fatty acid desaturase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Mal33_08530</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016717">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03505">
        <property type="entry name" value="Delta9-FADS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015876">
        <property type="entry name" value="Acyl-CoA_DS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11351">
        <property type="entry name" value="PTHR11351"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00075">
        <property type="entry name" value="FACDDSATRASE"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="41"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="186"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="210"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="domain" description="FA_desaturase" evidence="8">
        <location>
            <begin position="65"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV54888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="319" mass="36486" checksum="F00B5FF5F3FAF795" modified="2019-10-16" version="1">MATVVDDAFDLAEQTGIDAGEVAKSKKQKAANLSREERTIVNTYSIIWLVAAHVGAIFAIWTFTWPALIAMVTLHWITGGLGICLGYHRYLTHTGFQSHRWVKYMFAVIGSLAGEGSPLDWVADHRKHHAESDQPGDPHSPNDGAWWSHMFWLAYSTHDGDREAYFKRWIPDLAADRGMRFIEKMFLPLNFALGVALAVGGYLYGGSEMAISMVVWGMFLRLVFVLHSTWLVNSASHMWGYRNYETTDKSRNNWWVALVTYGEGWHNNHHAYPRMAKHGHKWWEIDLTYMAIRAMQKVGLIWKVVDYRNVAEKKAKQGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPA9</accession>
    <name>A0A518IPA9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Neutral/alkaline non-lysosomal ceramidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_08970</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031329">
        <property type="entry name" value="NEUT/ALK_ceramidase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04734">
        <property type="entry name" value="Ceramidase_alk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021883437" evidence="1">
        <location>
            <begin position="19"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="domain" description="Ceramidase_alk" evidence="2">
        <location>
            <begin position="33"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="466" mass="51323" checksum="71D56CF0E4BA8EDA" modified="2019-10-16" version="1" precursor="true">MKWLTCFLFVLLPLTASAQPWQAGSARISITPDEPIWMAGYGGRDHPAEGKLTDLWAKSLVLQDAAGHTAVLITLDLVGIHRDTTTKICDQIGKKHNLSRDQIAINCSHTHTGPAVGANLGPLHYVQVPEEQKQQLDDYEQQLIEKIVSIVDSSFESLQPSWLTWGNGRCSVAVNRRDNVQNDVPALRVQGKLNGPSDHDVPVLLVRDADQKLRTVVFGYACHATVLGIYQWSGDYPGYAQIEVEERYPEAIAMFWAGCGADQNPLPRRTIELAQQYGKRLGTAVAEVVEGFVHPVESSLQTSYTELDLPLVGVPTVEEVIQTRETTKNKFERGRAEYILGRLGDAKALDETYPYPVASWKIGNDIRMVFLGGEVVVDYALRLKSTAAGTPDDSPTMIWVAGYSNDVMAYIPSRRVLNEGGYEGGGSNVYYGIPGLWSEKIENMIAGEVAKQWATPKPQPAETSSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPI9</accession>
    <name>A0A518IPI9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Type I phosphodiesterase / nucleotide pyrophosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_09790</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006124">
        <property type="entry name" value="Metalloenzyme"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01676">
        <property type="entry name" value="Metalloenzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022197111" evidence="1">
        <location>
            <begin position="27"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="domain" description="Metalloenzyme" evidence="2">
        <location>
            <begin position="227"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="371" mass="41520" checksum="CCDC9ED0A5C2861A" modified="2019-10-16" version="1" precursor="true">MTKTKTLSLLLIASLFLTCSPRPANAADRRTENVVLISIDGLRWQDLFSGADARLMNRDDGGVRELDPLRQRFDASTSEARRARLMPFFWSVIAKQGQVYGDVNAGSVVRVTNGRYFSYPGYSELLCGFGDETIDSNAKRPNKNVSVLEWLNGKPAYRDRIAAFGSWDVFPFILNQQRSGIYVNAGWQDLDVFGNERELAQWNLLSNSLPRYWSAVRYDAFTARGALEYLKVKQPRVLYVALGETDDWAHDGRYDQYLDAALRTDQAIEQLWNTCQKIDQYRDKTTFIITTDHGRGDDRVGWKSHGASIPGSEFIWIAVLGPDTPPLSKPSTAELTQAQVAATVAAALGEDFTASDNRIAKPLTKAFDVSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQ41</accession>
    <name>A0A518IQ41_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Methyltransf_21 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_11890</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006342">
        <property type="entry name" value="FkbM_mtfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026913">
        <property type="entry name" value="METTL24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32026">
        <property type="entry name" value="PTHR32026"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05050">
        <property type="entry name" value="Methyltransf_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01444">
        <property type="entry name" value="fkbM_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransf_21" evidence="1">
        <location>
            <begin position="74"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="248" mass="28079" checksum="43C2D576A9F4EFB1" modified="2019-10-16" version="1">MQKKVLSNLKRKCRRLLKQASGRYRHLDADVRVGMRWCGSLYGGFYVCHECIPSNAIVYSFGIGEDVSFDLSMIRDFGCRVYGFDPTPRSAEWVRRQDISRRFSFFEFGLGERCGSETFFLPRNSHNVSGSFVLQGYVDSSNAIKLEMKDFATICRELGHNQVDVLKMDIEGAEYDVLESVVNSGVRIDQLLIEFHDRFFDDGLARTKAAVAMLKDSGFQLFGASDSLEELSFIHRSVVSQASRSLAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQF5</accession>
    <name>A0A518IQF5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_12990</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="198" mass="20622" checksum="3336E6AEC303C831" modified="2019-10-16" version="1">MFPMTSMKSNAPDNSKIVGRASFRQIGCLLALSLVLAGCDAASDAGSAAAPAVDSEFLLAEVPADAVSISDAKQGLEAGGPVTVIARITAGEHDPFEADKAMFLMKSDTTTTLDAEAAAAHEGPGHDPDNCPFCKQKNNPTDSVAIVRFLDEEGKILPQDAREMLGVKKDQVVVVQGTASVDPLGHLMIDASGLFIVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQN4</accession>
    <name>A0A518IQN4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cation efflux system protein CusB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">cusB_2</name>
        <name evidence="5" type="ORF">Mal33_13660</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="match status" value="1"/>
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            <end position="84"/>
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            <end position="142"/>
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            <end position="393"/>
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            <end position="441"/>
        </location>
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            <begin position="1"/>
            <end position="58"/>
        </location>
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            <end position="15"/>
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            <begin position="43"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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        <source>
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        </source>
    </evidence>
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            <dbReference type="Pfam" id="PF19335"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="QDV55395.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="711" mass="76423" checksum="5FD55B6611576DF5" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQU5</accession>
    <name>A0A518IQU5_9BACT</name>
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        <dbReference type="NCBI Taxonomy" id="2527990"/>
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            <taxon>Planctomycetia</taxon>
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        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
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                <person name="Mascher T."/>
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                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="UniProt"/>
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        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03571">
        <property type="entry name" value="Peptidase_M49"/>
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    </dbReference>
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    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022075050" evidence="3">
        <location>
            <begin position="21"/>
            <end position="677"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV55461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="677" mass="75778" checksum="0D26F20394C39062" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
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    <protein>
        <submittedName>
            <fullName evidence="7">Putative ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Mal33_14340</name>
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        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetia</taxon>
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        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
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        <property type="protein sequence ID" value="QDV55460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
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        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
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        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
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        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
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        <location>
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            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
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            <end position="101"/>
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    <feature type="transmembrane region" description="Helical" evidence="5">
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    </feature>
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        <location>
            <begin position="267"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="294"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="6">
        <location>
            <begin position="358"/>
            <end position="593"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV55460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="602" mass="65285" checksum="8A865260C6CA4423" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IR48</accession>
    <name>A0A518IR48_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_15000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="25"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="175"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="199" mass="22152" checksum="8D1DD83A58906AE3" modified="2019-10-16" version="1" precursor="true">MNNPTDEPQQTAPIYRRIARRCTGFTLVELVVAMSFGSVVMLLAIGIVHQSLTISQLGQARADQDRALVRLDRQFRQDVHRSEGFELPDPQTLELAIDDTRVVYTFDSNKIQRQTTVDSKRQDRELFLLNDRSQIELLTLDAPQRLGIVVRSDPGLQGVPPRTDRQIIAAVGLLQKRMPSSNESPADSADSAATGDDAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IR58</accession>
    <name>A0A518IR58_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PSP1 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_15520</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007557">
        <property type="entry name" value="PSP1_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04468">
        <property type="entry name" value="PSP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51411">
        <property type="entry name" value="PSP1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PSP1 C-terminal" evidence="2">
        <location>
            <begin position="73"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="279"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="286"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="313" mass="35050" checksum="D5259BF703CEC72A" modified="2019-10-16" version="1">MSTATPTDETKASPMKYVVRCGSLRTLHVATSKSSFHYGEKVIVRTDRGMETGEVLVEATEHTLSHMTNPPGGQILRSLSGDDVNDLSHISDQGRKEFDACKRHIHRLGLDMKLVDIEHLFGGERVVVYYLADKRVDFRQLVRDLASEFQTRVEMRQIGVRDEAKLLADYGDCGKPVCCNTHLSAMPPVSMRMAKLQKATLDPSKISGRCGRLKCCLRYEFDTYEEMQRELPPPGAQVLTRDGKATVIFQEILAQQLLVQTEDNRRVLIDVSDVLSVVQKKPAGDNRSSSKSKKKQNSKNLDTPSKAEGEENL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRI4</accession>
    <name>A0A518IRI4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AAA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_16810</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13401">
        <property type="entry name" value="AAA_22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="2">
        <location>
            <begin position="50"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="424"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="583"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="584"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="612"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="632"/>
            <end position="648"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="764" mass="82081" checksum="82A1036DAF4549A3" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRL4</accession>
    <name>A0A518IRL4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_17070</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021741293" evidence="1">
        <location>
            <begin position="28"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="301" mass="32911" checksum="F0687B9D0EF86A7D" modified="2019-10-16" version="1" precursor="true">MFKMLNANVLRSSVLATTTMFSCFAGAVARAEAPAAKGSATEVTKREGLVAFWDFQEPAGQPRISRGGEPLALQEMEGPIARVDGGVFGPHAARIRSGQWFMIPRPQIGGLDIHGPEAQVTVVAWIRREGKQHWQAIAGAWDETRRKRQYCLFLNAPRGTKADEMKRYPLKNHIHGHVSGVGGPTPGERYCITYSSGATEIPLKQWHCLAMTYDGKQSCVYVDGRLDARSQYNPFPYTKGLFDGGSDGAAFTVGAVHRSEEWGNFFDGEIGGLAVFRRALSESELLSLANQIPLPDASGDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRT5</accession>
    <name>A0A518IRT5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">AMP nucleosidase</fullName>
            <ecNumber evidence="2">3.2.2.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">amn</name>
        <name evidence="2" type="ORF">Mal33_17790</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.2.2.4" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008714">
        <property type="term" value="F:AMP nucleosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044209">
        <property type="term" value="P:AMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009116">
        <property type="term" value="P:nucleoside metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011271">
        <property type="entry name" value="AMP_nucleosidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000845">
        <property type="entry name" value="Nucleoside_phosphorylase_d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035994">
        <property type="entry name" value="Nucleoside_phosphorylase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43691:SF6">
        <property type="entry name" value="PTHR43691:SF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01048">
        <property type="entry name" value="PNP_UDP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53167">
        <property type="entry name" value="SSF53167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNP_UDP_1" evidence="1">
        <location>
            <begin position="178"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="392" mass="43916" checksum="A3EE9E34D573E4ED" modified="2019-10-16" version="1">MSETMQILPGQSQADLDQQIEAACALMERHYASGVYSKLTVVRSWSKHNPTISGSIARPSAFRWYLRRELTKLAQRGAQLHVAPSRARVDLNAPKLLQLIDESDFDHTRKKVFLFGPERAELSIQRLEHYTGTQVEDFQRYVLLTNYQMHMNAFIEAYPDCIRPQRTDVQMPALHQRTVNNDGVTIINIGVGPSNAKNLTDHIAVLRPDAMLMVGHCAGIRNHQEIGDFVLGSGYMRADRLLDQTLPTSVPLSPNFVLNRNLARVLDERKLPYRFGVVYTTIDRNWELTLRGTLADLRASRSIAVDMESATVAANGFRYRIPSATLLCVSDKPLHGKPKLAAEALEFYKKTKSQHLAVAIAAIELAKQEFPGGFPNSDIRAMDEPLLGGPET</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRU1</accession>
    <name>A0A518IRU1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7 9">GTPase Der</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">GTP-binding protein EngA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 12" type="primary">der</name>
        <name evidence="12" type="ORF">Mal33_17950</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">Mal33</strain>
        </source>
    </reference>
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        <text evidence="7 9">GTPase that plays an essential role in the late steps of ribosome biogenesis.</text>
    </comment>
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        <text evidence="7">Associates with the 50S ribosomal subunit.</text>
    </comment>
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    </comment>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR032859">
        <property type="entry name" value="KH_dom-like"/>
    </dbReference>
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        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
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        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
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        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
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        <property type="entry name" value="KH_dom-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="GTP-binding_EngA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
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        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="GTPase_EngA"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51712">
        <property type="entry name" value="G_ENGA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5 7 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 7" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="EngA-type G" evidence="11">
        <location>
            <begin position="176"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="433"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="10"/>
            <end position="17"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <label>1</label>
        </ligand>
    </feature>
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        <location>
            <begin position="57"/>
            <end position="61"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <label>1</label>
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            <begin position="120"/>
            <end position="123"/>
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        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <label>1</label>
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        <location>
            <begin position="182"/>
            <end position="189"/>
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        <ligand>
            <name>GTP</name>
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        <ligand>
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        </source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="453" mass="51636" checksum="89EA44C68436E5DB" modified="2019-10-16" version="1">MSMPKVAIVGRPNVGKSSIFNWLAGRRIAIVDDYEGVTRDRMTTLIEHEGNFFELIDTGGMGVVDSDDLTADVEAQIEVAIATADVILFVVDIRTGLMPLDSLVAERLRSIDRPIVLLANKADHDNLDISAEEFHKLGRGHLICVSAEQKRHRDELMQLIVDRLPPSSDRAVDAHMKFAIVGRRNVGKSTFVNSLAQAKRMIVSEVAGTTRDSVDVNFELDGHQFTAIDTPGLRRRRSVRTDLDYYGMHRAQRSIRRADVSLMFFDASEKISKVDKQLVGYIADEYKPCVFVVNKWDLYHDEMPTERWVKYLRSQFPTMQYAPIAFITGQTGKNIKALLNHSQMLFKQARERTSTGRLNRIVQAAIEHQEPPMFQNRRPKIYYATQVSTEPPTIVLMCNDPKGFAPDYRRFLLSVLRDNLPFSEVPIKMYLQKREQRDPTAPPEVDQENERVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRY6</accession>
    <name>A0A518IRY6_9BACT</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
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        <name type="scientific">Rosistilla oblonga</name>
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    </organism>
    <reference evidence="2 3" key="1">
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            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
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                <person name="Jeske O."/>
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                <person name="Storesund J.E."/>
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                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
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                <person name="Jogler C."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
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        <property type="project" value="UniProtKB-KW"/>
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        </location>
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            <dbReference type="EMBL" id="QDV55856.1"/>
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        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="559" mass="62403" checksum="966801A5C3F0A07D" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IS63</accession>
    <name>A0A518IS63_9BACT</name>
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        <submittedName>
            <fullName evidence="2">Outer membrane biogenesis protein BamB</fullName>
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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                <person name="Kohn T."/>
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                <person name="Rast P."/>
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                <person name="Bunk B."/>
                <person name="Jeske O."/>
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                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
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                <person name="Lage O.M."/>
                <person name="Pohl T."/>
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                <person name="Mueller R.-W."/>
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                <person name="Amann R."/>
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                <person name="Devos D.P."/>
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                <person name="Ovreas L."/>
                <person name="Rohde M."/>
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                <person name="Jogler C."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
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        </location>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="QDV55937.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1571" mass="173460" checksum="AE91C7AD3217F08F" modified="2019-10-16" version="1"> </sequence>
</entry>
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    <accession>A0A518ISK0</accession>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="424" mass="45915" checksum="F4146DC10C5F57C7" modified="2019-10-16" version="1">MSQMQQQRRNFRIGFTLVELLIVVSIITLVTAIALPTVRDQLRDQKATRTASLVRSYLDTARARAVNTGKPYGVVIKRSGTSGFESARSIELRYCRLASSYSGDESDAFALITPPGTYDASIRIVQFPNTDGTDPVYGNDVIRTPPPGFVVVGDTIQFDDSDVNFQIRQVTYDTSTPPNLVSLLIEPVDPSVVSDVAVGAGSSATRGYSISRFRETASLPLYLQTGTMIDLAFSGYRRGDASVKDYGTPFGSHQRLAACQFSPMEIEHQYDLARGATSTAAYDTAGTSPVVASARTYPYGDIYILFAPNGTVYSVIYGELYGAPGSKAIRMQHHLVNSDIYLMVGREGLTDVADPMSLSSKEQATAFDLQSVWVVINGVSGEVTTQTPNPIASVRDSGLQAAEKTPAEMHNGISALMHVSREKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISU6</accession>
    <name>A0A518ISU6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_21290</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021815779" evidence="1">
        <location>
            <begin position="33"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="316" mass="34854" checksum="B47B59A4463DA209" modified="2019-10-16" version="1" precursor="true">MLTLQSWLKTMLLAIGLIVASLVGAVGAFAQAAVAPVETAEQEKEANAKKATSEYLRITKLDNGKPDSMETSIVRFEGPAGSKYAGRVVDLIGVVHIGQKEYYEQLNERFADYDRVLYELVAPEGTTVSKEQAGEVRGPLGAMQLGMKDILNLDFQLEHIDYDAKNFRHADMSPEEFAADMAERGDSVMKMVFRMLGSGMATQAAAEPAASDTALLFALFAPDRARRMKQIMASQFEDMEIATAAMADATGKSTIITERNAKAFSVLADELQRGSRKVAVFYGAGHLPDMADRLRDDFQMKKTQTEWFQAWDLQKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISW7</accession>
    <name>A0A518ISW7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Elongation factor P-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">yeiP</name>
        <name evidence="4" type="ORF">Mal33_21320</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the elongation factor P family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04470">
        <property type="entry name" value="S1_EF-P_repeat_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05794">
        <property type="entry name" value="S1_EF-P_repeat_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015365">
        <property type="entry name" value="Elong-fact-P_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_L2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020599">
        <property type="entry name" value="Transl_elong_fac_P/YeiP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013185">
        <property type="entry name" value="Transl_elong_KOW-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001059">
        <property type="entry name" value="Transl_elong_P/YeiP_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013852">
        <property type="entry name" value="Transl_elong_P/YeiP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30053">
        <property type="entry name" value="PTHR30053"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01132">
        <property type="entry name" value="EFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08207">
        <property type="entry name" value="EFP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09285">
        <property type="entry name" value="Elong-fact-P_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005901">
        <property type="entry name" value="EF-P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01185">
        <property type="entry name" value="EFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00841">
        <property type="entry name" value="Elong-fact-P_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01275">
        <property type="entry name" value="EFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EFP" evidence="3">
        <location>
            <begin position="68"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="Elong-fact-P_C" evidence="2">
        <location>
            <begin position="131"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV56153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="187" mass="20709" checksum="3A156F6400208644" modified="2019-10-16" version="1">MQAKEIKTGTVVVYNGDPLLILGIQVQTPSARGAATLYKFRGRNLVSRQKVDLTLKGTDALEMADFHKRDVQVMYRDAEQIHLMDTENYNQYAMNLDDVGDQLLYLSEGLEGIRALIYNDGPVGLELPASVEMDITQCDPAVKGNSATSRSKPATLETGLVIQVPEYIKDGERIKVDTRTGEFLSRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISZ6</accession>
    <name>A0A518ISZ6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_21800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="134" mass="14790" checksum="84A2CC3631DBD718" modified="2019-10-16" version="1">MRNIFILGILVVGAFMAGWFTIDRDGEQTTIKINRTEIREDAKQAIDRGKEYLERQNLGAPHEEGQVNALYNTVEQAASKLRYVQQGGEYGAPAGYQPPAYQPAGAPNQLQYSYPTANQPQPAGNPSGFTPARY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IT52</accession>
    <name>A0A518IT52_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_22540</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="191" mass="21332" checksum="969FE2D4E2B84B7E" modified="2019-10-16" version="1">MGVLAHETSRKEGMNLKPILQSILEDYALPLGGDHGVAHWARVLENGLKLADATGANVKVVSLFAVLHDSRRINEVTDPEHGTRAAEFAAELRGSLLDLDDHDFRLLYRACEGHTHERNHPDVTIQTCWDSDRLDLGRVGIMPHPSRLCTEFAKRPETIKWADGRASFGVVPTFVLDEWGIDLERGFRGEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITD9</accession>
    <name>A0A518ITD9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Outer membrane protein assembly factor BamD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">bamD_1</name>
        <name evidence="3" type="ORF">Mal33_23420</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13174">
        <property type="entry name" value="TPR_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021781781" evidence="2">
        <location>
            <begin position="28"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="537"/>
            <end position="570"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="626" mass="67709" checksum="558E7CD35D832C16" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITV5</accession>
    <name>A0A518ITV5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_24810</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="57" mass="6350" checksum="50DD8FD7CB5C5327" modified="2019-10-16" version="1">MPNKRPGWIGDLIENGYKARPAQDQLGKKPPPDVRSVQKPKQLPPPPPAPRSNNDKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IU38</accession>
    <name>A0A518IU38_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyltransferase Gtf1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">gtf1</name>
        <name evidence="2" type="ORF">Mal33_25980</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="139"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="325" mass="36875" checksum="9876904780F144B7" modified="2019-10-16" version="1">MSTRPVPHPPSWFNSLNPARWPKTDTQHIQRWLAKEQPDLALVTLGYHLNTVSPAAELMRRQIPYAINVQCASPDYLDSYFLDAFRAAYAGAARVYFVSQENLERVETMLAMRIETAKIIDNPFNVSWDAQPAWPTDRDGFRLACVGRLHFPSKGQDLLIDVLRQDKWRQRNLSLHLYGESQGFLRQTEDLIARHGLQDQIHYEGFSETIENLWANHHGLVLPSRFEGAALAVVEALLCNRVCVTTAVGRNRELIRDGETGFIAPAATAELIDHALEAAWQKRDRWQEIGQLAGQHIRQRYHEDPVAVLYSDLMALAAEQGVGNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IU97</accession>
    <name>A0A518IU97_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glutamate-pyruvate aminotransferase AlaC</fullName>
            <ecNumber evidence="3">2.6.1.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">alaC</name>
        <name evidence="3" type="ORF">Mal33_26410</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.6.1.2" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004021">
        <property type="term" value="F:L-alanine:2-oxoglutarate aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="3" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="2">
        <location>
            <begin position="56"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="425" mass="47473" checksum="B0D550B8FA676D31" modified="2019-10-16" version="1">MSDQINLDGPAIDQSTEDPQPEPFQIRVANRVDRLPPYMFGRINAMLYQKRRDGSDVIDMGMGNPSDPPQTDVVEKLTEAAHDERNHGYSKSNGLLNLRREVCNKYERKYDVQLEADHEVIACLGSKEGFSHMCLALMGPGDTAIIPSPYFPIHMYAVILASGNVVTLDVFDPEKFLRNVEYTCQTFTPRPKLLIINYPHNPSAATIEPDFFVEVVRLAKKYGFMVIHDFAYADIGFDGYQPPSFLSAPGAKDVGVEFTTMSKGYNMAGWRVGFCAGNADMIRALGTIKGYYDYGMFQAVQIAAIVAMRDTEDAVAEQALVYQSRRDALVDGLRRIGWEIDPPKAGMFVWAKVPEQWRHMSTMDFAMMLLEKGDVAVSPGSGFGPAGEGYLRMSLVENEQRLRQAVRQISRCLDKQSALESEATT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUG9</accession>
    <name>A0A518IUG9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zinc metalloprotease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">rip3_2</name>
        <name evidence="14" type="ORF">Mal33_27080</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="8 10">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="8 10">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the peptidase M50B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008915">
        <property type="entry name" value="Peptidase_M50"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016483">
        <property type="entry name" value="UCP006404_Pept_M50_CBS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02163">
        <property type="entry name" value="Peptidase_M50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006404">
        <property type="entry name" value="UCP006404_Pept_M50_CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0129">CBS domain</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 14" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="8 14" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8 10" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="100"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="138"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="179"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="13">
        <location>
            <begin position="303"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="360"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="61"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR006404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR006404-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR006404-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="QDV56710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="379" mass="41897" checksum="D330AC8ED15A0AFE" modified="2019-10-16" version="1">MMSRRFKLGTFFGIALFIHWSFFLMPALVAYSEWSNGGRWIDVLLTLGFVVLLFACVILHEYGHVLAARAFGVGTRDITMLPIGGVARLERMPEEPWQELIVAVAGPAVNVLIAATLGIGIVAFYGFNLDADGESNMFAHRLFAVNIALIVFNMIPAFPMDGGRVFRSVASMFTNHRRATWLAMRLGQVIAIALFALGISNLSNLPFLPFIAAFIFWVGMMEYRQVDIASQVKDLRVRDAMLRQFCVAPIDSSIADFAERAADQLQRTFPVVEHGLYRGVLQLEQIATAMQTANGQQQTVGEIARWDSITVDEDAPLEEVLVGMPRDATQIPVLDTTNKVVGLLDTDSCLRRVALRSGRSHNPAAPASIDYYSPPGDER</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUN6</accession>
    <name>A0A518IUN6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Alkaline phosphatase</fullName>
            <ecNumber evidence="5">3.1.3.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">phoA_2</name>
        <name evidence="5" type="ORF">Mal33_28030</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.3.1" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003993">
        <property type="term" value="F:acid phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004035">
        <property type="term" value="F:alkaline phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039331">
        <property type="entry name" value="PPA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008963">
        <property type="entry name" value="Purple_acid_Pase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015914">
        <property type="entry name" value="Purple_acid_Pase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22953">
        <property type="entry name" value="PTHR22953"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16656">
        <property type="entry name" value="Pur_ac_phosph_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49363">
        <property type="entry name" value="SSF49363"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021837028" evidence="2">
        <location>
            <begin position="24"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="domain" description="Pur_ac_phosph_N" evidence="4">
        <location>
            <begin position="49"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="Metallophos" evidence="3">
        <location>
            <begin position="157"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV56803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="481" mass="53849" checksum="F9272500410D6331" modified="2019-10-16" version="1" precursor="true">MMHLRTLLLTSFALLWVPQLGIAHEGEHGHSHAPIAVKPDEMYEPTAMPDRIVLTWDGDPHTSQAVTWRTSTAVNIGLAEIAVAEAGPGFPAKAEQIAAVSEALKTDLNTAHFHSVSFRDLTPGTRYAYRVGDGVNWSEWFHFSTPTTKHEPFSFIYFGDAQNNLRSMWSRVIREAYRDAPKAAFLLHAGDLVNRATADAEWGEWFGAGAWLNAMTPNIAVPGNHEQSKSADGKSRQLTAHWRPSFTFPQNGPKGLEESCFTLVYQNLRVIALNSNEMQKEQAVWLEDVLANNKSEWVVCTFHHPIFSTGKGRDNRSLRAAWKPILDKYKVDLVLQGHDHTYGRTGFSVPGVEVSEKEFSTFGVDDKAAAKEGDKEINVGTVNVPTGVQNVDPEHGTVYVVSVSGPKMYDNTRWPFMKRLAEDTQLYQVIHIDGDQLRFEARTAIGELYDAFELHKQADGEINKLVEIEVEMPQNLRPKKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUP2</accession>
    <name>A0A518IUP2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Ferredoxin-dependent glutamate synthase 1</fullName>
            <ecNumber evidence="16">1.4.7.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">gltB_2</name>
        <name evidence="16" type="ORF">Mal33_28050</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="14">Amino-acid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glutamate synthase family.</text>
    </comment>
    <dbReference type="EC" id="1.4.7.1" evidence="16"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00246"/>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051538">
        <property type="term" value="F:3 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016041">
        <property type="term" value="F:glutamate synthase (ferredoxin) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006537">
        <property type="term" value="P:glutamate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00982">
        <property type="entry name" value="gltB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02808">
        <property type="entry name" value="GltS_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002489">
        <property type="entry name" value="Glu_synth_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036485">
        <property type="entry name" value="Glu_synth_asu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006982">
        <property type="entry name" value="Glu_synth_centr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002932">
        <property type="entry name" value="Glu_synthdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00310">
        <property type="entry name" value="GATase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04898">
        <property type="entry name" value="Glu_syn_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01645">
        <property type="entry name" value="Glu_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01493">
        <property type="entry name" value="GXGXG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69336">
        <property type="entry name" value="SSF69336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0003">3Fe-4S</keyword>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0288">FMN</keyword>
    <keyword evidence="12" id="KW-0314">Glutamate biosynthesis</keyword>
    <keyword evidence="8" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="11" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 16" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="15">
        <location>
            <begin position="23"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00029440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="QDV56805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1520" mass="166826" checksum="8B51703EB135DD98" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUT5</accession>
    <name>A0A518IUT5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_28550</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008138">
        <property type="term" value="F:protein tyrosine/serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:protein dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00195">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="SSF52799"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50054">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="3">
        <location>
            <begin position="44"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="domain" description="TYR_PHOSPHATASE_2" evidence="4">
        <location>
            <begin position="109"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV56854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="187" mass="21645" checksum="BEA75CA584256929" modified="2019-10-16" version="1">MDPKPETPLPKNVPLWQRLYARGVFYPTLTWNMLLGRALKVRRWWDPIDPHVIVGAYPFARDVSLMYEQGVRAVVNTCEEYAGPQAVYDAMGIEQFRMPTTDFTHPKLEDIERAVEFVQSHVAQEHTVYIHCKAGRARSATVALCWLIKYRGQTPEQAQKILLEHRPHVNPHVYLRPVVAEFVKRIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUU7</accession>
    <name>A0A518IUU7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_28640</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="175" mass="19281" checksum="3749780770EAAC7E" modified="2019-10-16" version="1">MIQFNVSQSLRLFALLLATVCHHLPAHGEDATAAGELGTSVLNQESSVDDREVYIVTSKLRGTFPKVGAILHASIAICPQGVSPVVYENGVPVSNCYECKLYGTQVFERGFQLERKRIGVTATKVCGISAETAERRMRNHHALNIPILNDCRHHVIQALGIHNRHGHLKRPISLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUW2</accession>
    <name>A0A518IUW2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">von Willebrand factor type A domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_28660</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028087">
        <property type="entry name" value="Tad_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13400">
        <property type="entry name" value="Tad"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00092">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="2">
        <location>
            <begin position="171"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="350" mass="37101" checksum="69841B03E99C9FC7" modified="2019-10-16" version="1">MTQQTTQSARRRQTPAQRRRGAMMIFVAVLMIAFLATVVFSIDLAHMHLTRTQLRSATDAAAKAAAQELSATQDRGAARRQAKAIAGQNLVAGKPLLLNNADIKFGRSVADPQSGKFVFDTAGTPINSIQIHGDRSKGSASGSVKLLFGGIFGVEDFQPEQEATATFLERDVVLVVDRSGSMFGQKANDLKNAINIFVNTLSGTPVDEVVGLASYSNTATADVALTTSLGQITTAMNSMRFSGTTSISAGMSAGGAILSGGRNTDFVERTMIVMTDGIHNAGRDPQIDAQILANQGVFIHTITFGAGADIARMKRIATTGRGKHFHAANGAQLIEIYREIALTLSTLITK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVA5</accession>
    <name>A0A518IVA5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UPF0178 protein Mal33_30170</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_30170</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the UPF0178 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00489">
        <property type="entry name" value="UPF0178"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003791">
        <property type="entry name" value="UPF0178"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35146">
        <property type="entry name" value="PTHR35146"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02639">
        <property type="entry name" value="DUF188"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="157" mass="17388" checksum="632EF7400077FF0C" modified="2019-10-16" version="1">MKIWIDADAAPMDVKQIVFRAAKRLDVETILVANRMMEVPASLSMVRSIQVREGADQADRYIAAEGQRGDLAITADLPLAGDLVEKGLFVIDPRGEEYSPETITSRLSMRNFMDDLRGAGMVVGRTAPYGETDKKAFAATFDRLLTRAIRLAERAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVM0</accession>
    <name>A0A518IVM0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF2383 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_31280</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011971">
        <property type="entry name" value="CHP02284"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019052">
        <property type="entry name" value="DUF2383"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016920">
        <property type="entry name" value="UCP029477"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09537">
        <property type="entry name" value="DUF2383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029477">
        <property type="entry name" value="UCP029477"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02284">
        <property type="entry name" value="TIGR02284"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2383" evidence="1">
        <location>
            <begin position="13"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="156" mass="17511" checksum="68362FF7A9F6D371" modified="2019-10-16" version="1">MSLETKTNLNESTVTKLQKLIRANIDAYDGFRESAEEIDDITLANLFREVANERSALATELQNYVQWNGAEAEEDGSVAASVHRSWINVRSKINGGDPYVILIEAERGEDHIKHAYEDVLKETAGSAMNDVLTAQYAIVKAGHDKIRDLRDSYKNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVP9</accession>
    <name>A0A518IVP9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Sensory/regulatory protein RpfC</fullName>
            <ecNumber evidence="9">2.7.13.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">rpfC_2</name>
        <name evidence="9" type="ORF">Mal33_31730</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.13.3" evidence="9"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00088">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036641">
        <property type="entry name" value="HPT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008207">
        <property type="entry name" value="Sig_transdc_His_kin_Hpt_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01627">
        <property type="entry name" value="Hpt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00073">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47226">
        <property type="entry name" value="SSF47226"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50894">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="1 3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="29"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="6">
        <location>
            <begin position="344"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="7">
        <location>
            <begin position="601"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="domain" description="HPt" evidence="8">
        <location>
            <begin position="754"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="721"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="3">
        <location>
            <position position="650"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphohistidine" evidence="2">
        <location>
            <position position="793"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV57172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="853" mass="92749" checksum="40612804AB49C770" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVS5</accession>
    <name>A0A518IVS5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF58 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_31940</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002881">
        <property type="entry name" value="DUF58"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01882">
        <property type="entry name" value="DUF58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF58" evidence="1">
        <location>
            <begin position="33"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="283" mass="32116" checksum="F86EDDD1633C9949" modified="2019-10-16" version="1">MLGRLERMELVSRKVFRGRMKGERRSRRKGQSVEFADFRNYVPGDDLRFIDWNMYARLDKLFLKLFLEEEDLHFYALIDASASMSFGDPTKLHVAKQLAAALGYVGMCRADRVRVAALGPPGAAAPTLRGKASLWKMLNYLDTVQPVHNVSLADGVKDFVLRNPGTGIVVLLTDLMDKQGYEAALRMLLGRRMDVFVVHILAPEEIDPPLQGDLKLIDVEDADEAEVTVNGALLQRYKQTVDAFIDQSRTFCSQRDMTYLLTRTDQSVEELVTKYLRQRGVVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVX3</accession>
    <name>A0A518IVX3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_32330</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="107"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="153" mass="15650" checksum="876237DE3BCE5F23" modified="2019-10-16" version="1">MKSMNYFAGRSSLVRFATSGAAIALLCIVGCGPAEKRVATAPVKGKVVYKGAPVTTGTVMFIPSGGGPPATGEIQPDGSYSLKTYEPEDGAVVGRHAVTISAIELATGSPEDPASDPKLLVPTKYSSSKMSGLTAEVSDGENAVDFELEGPLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVY6</accession>
    <name>A0A518IVY6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Riboflavin biosynthesis protein RibBA</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="12">3,4-dihydroxy-2-butanone 4-phosphate synthase</fullName>
                <shortName evidence="12">DHBP synthase</shortName>
                <ecNumber evidence="12">4.1.99.12</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="12">GTP cyclohydrolase-2</fullName>
                <ecNumber evidence="12">3.5.4.25</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="12">GTP cyclohydrolase II</fullName>
            </alternativeName>
        </domain>
    </protein>
    <gene>
        <name evidence="12 14" type="primary">ribBA</name>
        <name evidence="14" type="ORF">Mal33_32560</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 12">Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.</text>
    </comment>
    <comment type="function">
        <text evidence="12">Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>D-ribulose 5-phosphate = (2S)-2-hydroxy-3-oxobutyl phosphate + formate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18457"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="ChEBI" id="CHEBI:58830"/>
            <dbReference type="EC" id="4.1.99.12"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11 12">
            <text>GTP + 4 H2O = 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine + formate + 3 H(+) + 2 phosphate</text>
            <dbReference type="Rhea" id="RHEA:23704"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58614"/>
            <dbReference type="EC" id="3.5.4.25"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="12">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="12">Binds 2 divalent metal cations per subunit. Magnesium or manganese.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="12">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 12">Cofactor biosynthesis; riboflavin biosynthesis; 2-hydroxy-3-oxobutyl phosphate from D-ribulose 5-phosphate: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 12">Cofactor biosynthesis; riboflavin biosynthesis; 5-amino-6-(D-ribitylamino)uracil from GTP: step 1/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="12">In the C-terminal section; belongs to the GTP cyclohydrolase II family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 12">In the N-terminal section; belongs to the DHBP synthase family.</text>
    </comment>
    <dbReference type="EC" id="4.1.99.12" evidence="12"/>
    <dbReference type="EC" id="3.5.4.25" evidence="12"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00275">
        <property type="reaction ID" value="UER00399"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008686">
        <property type="term" value="F:3,4-dihydroxy-2-butanone-4-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003935">
        <property type="term" value="F:GTP cyclohydrolase II activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00641">
        <property type="entry name" value="GTP_cyclohydro2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00179">
        <property type="entry name" value="RibA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01283">
        <property type="entry name" value="RibBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017945">
        <property type="entry name" value="DHBP_synth_RibB-like_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000422">
        <property type="entry name" value="DHBP_synthase_RibB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032677">
        <property type="entry name" value="GTP_cyclohydro_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000926">
        <property type="entry name" value="RibA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036144">
        <property type="entry name" value="RibA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016299">
        <property type="entry name" value="Riboflavin_synth_RibBA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00926">
        <property type="entry name" value="DHBP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00925">
        <property type="entry name" value="GTP_cyclohydro2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142695">
        <property type="entry name" value="SSF142695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55821">
        <property type="entry name" value="SSF55821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00505">
        <property type="entry name" value="ribA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00506">
        <property type="entry name" value="ribB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 12" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="9 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-0456">Lyase</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="12" id="KW-0464">Manganese</keyword>
    <keyword evidence="7 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="8 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0686">Riboflavin biosynthesis</keyword>
    <keyword evidence="12" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="GTP_cyclohydro2" evidence="13">
        <location>
            <begin position="209"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="DHBP synthase" evidence="12">
        <location>
            <begin position="1"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="D-ribulose 5-phosphate binding" evidence="12">
        <location>
            <begin position="29"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="D-ribulose 5-phosphate binding" evidence="12">
        <location>
            <begin position="140"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="GTP cyclohydrolase II" evidence="12">
        <location>
            <begin position="202"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for GTP cyclohydrolase activity" evidence="12">
        <location>
            <position position="331"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile; for GTP cyclohydrolase activity" evidence="12">
        <location>
            <position position="333"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="30"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>D-ribulose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>D-ribulose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="254"/>
            <end position="258"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="259"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="270"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="272"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="275"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="297"/>
            <end position="299"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="319"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="354"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="359"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="site" description="Essential for DHBP synthase activity" evidence="12">
        <location>
            <position position="126"/>
        </location>
    </feature>
    <feature type="site" description="Essential for DHBP synthase activity" evidence="12">
        <location>
            <position position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00029293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="QDV57252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="410" mass="44932" checksum="10F5764B9A6F06D6" modified="2019-10-16" version="1">MSSPFNSVPEAVDAIARGEIVIVLDAENRENEGDYICAAEKASIENVNFMLSGRGQLCVAVLPDVCNRLDLHPLVERNDAPLKTAFQTPVDHRNAKTGITAAERSETIQALIQPHSHAEDFVRPGHVYPLLAKEGGVLRRAGHTEAAVDLARMAGLEPAGALCEVLNESGDRATRDDLLALAKKHNLKIITIEELIAHRRVNEKLVSRNAQADLPTSFGDFKIIVYDVQFEDQEPIALVYGDLASQDGPPPLVRMHSSCFTGDLVDSLRCDCGDQLKMALKVISSEGRGALVYLPQEGRGIGLAQKIRAYALQDQGLDTVEANHALGFKADMRDYGIGLQILKDLGLREVRLLTNNPKKTEAFNLRGFDLQVVDQVPIISESNVHNARYLQTKRDKMGHQLPSDPVESAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWC3</accession>
    <name>A0A518IWC3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_34080</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1285" mass="141123" checksum="B57ECDC2CE11CEF5" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWF9</accession>
    <name>A0A518IWF9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_34330</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035402">
        <property type="entry name" value="DUF1611-N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035086">
        <property type="entry name" value="DUF1611_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011669">
        <property type="entry name" value="UCP026760"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40690">
        <property type="entry name" value="PTHR40690"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07755">
        <property type="entry name" value="DUF1611"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17396">
        <property type="entry name" value="DUF1611_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF026760">
        <property type="entry name" value="UCP026760"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1611_N" evidence="2">
        <location>
            <begin position="60"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1611" evidence="1">
        <location>
            <begin position="156"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="365" mass="39200" checksum="A143FEA30E7652E1" modified="2019-10-16" version="1">MNTTVLETSRSAVAGLDSILQYRRIAIAVGTDAPLSNCKTTISLLRYRGEHCVAVIDPAHRGKTTQEVYGVGGETPIVASIAEVESPDAMFIGISPAGGAMPQSLRTTIGEGVDRGLDVISGLHEFLVEDDDLWQAAQQSGSRLIDVRRNLHRKTASGIAFRDGCLRIHAVGHDCSVGKMVTMLELERGLKERQRNAKFLATGQTGIMVVGNGVPVDCVVSDFVNGAVENLVQQNEEHDILLIEGQGSITHPAFSAVTLGLLHGCAPQGLILCYEAGRPHVKGMPHVALKSLQHYRELYEALASARSPAQVIGIAMNGRNLTAEQAEIEKREVQEQLGLPVCDVYRDGPGLLVDAVLQMQKRSGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWG6</accession>
    <name>A0A518IWG6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transcription termination factor Rho</fullName>
            <ecNumber evidence="6">3.6.4.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">ATP-dependent helicase Rho</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rho</name>
        <name evidence="10" type="ORF">Mal33_34440</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homohexamer. The homohexamer assembles into an open ring structure.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the Rho family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.-" evidence="6"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008186">
        <property type="term" value="F:ATP-dependent activity, acting on RNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006353">
        <property type="term" value="P:DNA-templated transcription, termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04459">
        <property type="entry name" value="Rho_CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01884">
        <property type="entry name" value="Rho"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011129">
        <property type="entry name" value="CSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011113">
        <property type="entry name" value="Rho_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004665">
        <property type="entry name" value="Term_rho"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46425">
        <property type="entry name" value="PTHR46425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07497">
        <property type="entry name" value="Rho_RNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00357">
        <property type="entry name" value="CSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00767">
        <property type="entry name" value="rho"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51856">
        <property type="entry name" value="RHO_RNA_BD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 6" id="KW-0347">Helicase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="1 6" id="KW-0806">Transcription termination</keyword>
    <feature type="domain" description="Rho RNA-BD" evidence="9">
        <location>
            <begin position="126"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="8"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="30"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="244"/>
            <end position="249"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="256"/>
            <end position="261"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="287"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV57434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="498" mass="55778" checksum="BC7D0D41166A424C" modified="2019-10-16" version="1">MEPRKPNRQNSSRPLQRGRNQSFGGGSRPRHPDAEVDQRIRELDAERDPLSLPEEIVVEATRAGGSVGVPQQRSDNAPMNLAQLQLLSRDELVALAEAEGVTDIEKCSRLDLSFSVLKRRMANNGLMYGEGTLEILPDGFGFLRSPDAHYISCPDDIYVSPSQIRRFGLQTGSSVAGQIRPPKENERYFALLRVEAINRRDPMDRQRNVRFEDLTPLHPNARIIMETDAHEMSTRVIDLLAPIGFGQRGLIVSPPRAGKTVLMQKMARSVLENYPDAYVIVLLVDERPEEVTDMEREVKGPHCEVISSTFDEPPARHIQVAQMVIEKAKRMVEYGIDVVIFLDSITRLGRAYNSEGGGTGKLLSGGLDAGALQKPKAFFGSARKLEEGGSLTILATALVDTGSRMDDVIFEEFKGTGNMEIVLDRNLVDRRIWPSIDPGRSGTRREEMLMDDEEHRRISILRRVMAELNPPEAMDMLIKQLKKTQNNAEFLLSLKEVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWW3</accession>
    <name>A0A518IWW3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ubiquinone biosynthesis O-methyltransferase</fullName>
            <ecNumber evidence="2">2.1.1.222</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ubiG_2</name>
        <name evidence="2" type="ORF">Mal33_35950</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.1.1.222" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
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        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0830">Ubiquinone</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="318"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="319"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="342" mass="38069" checksum="7195857886A39F0A" modified="2019-10-16" version="1">MVLGKTAGQAACRVCSSAGLELISTRDRRRQALETVVCTSCGLVQHAQIPTSEELAEFYSSQYRIDYNGEATPSNRRVYREWRRGRERFDALRPFIEPGDQVFEVGSGIGCNLRQFENFGCSVSGIEPGEGFCQYSRQQLGVNVRCAFLEDLADDARQDQSLVLLVHVLEHLPDPVDALRQIRRLMRPDGHLFVEVPDFGRPHAAPNRVFHYGHIYNFTEISLRNVAHKAGFRTQPVSLKSSHLPNLAMVLTPAPDAEKVPMVNGYRMAVDAYHRYTPLEYHLRPAKLRTAIGKAIDHVDEFLFASSQVARLRANRPAVSTARSGNNSSPQTAMASAVCASG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IX56</accession>
    <name>A0A518IX56_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Membrane dipeptidase (Peptidase family M19)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_36790</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070573">
        <property type="term" value="F:metallodipeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008257">
        <property type="entry name" value="Pept_M19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10443">
        <property type="entry name" value="PTHR10443"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01244">
        <property type="entry name" value="Peptidase_M19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51365">
        <property type="entry name" value="RENAL_DIPEPTIDASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="363" mass="39901" checksum="FE8AD8F99CEE5BB7" modified="2019-10-16" version="1">MRTMIDGHLDLAWNATSFDRDLRLSLDEIRTREQSMTDLKSRTRGTTCFPELQAGKIQVCIATLLARSGPATDRQTGYARTDLDFAHHIGAYAAAHAQLACYHLWEQQGAIRWIRTLADLEDHWSKCNGESKPPLGMILSMEGADPISDPAELPYWFGTGLRAIGLSHYGHGQYAAGTAVEGGLTEKGEQLLDAMAKLGMGLDVTHLADRAMEQAFDRFTGVLWASHHNSRTLVPGQRQLSDQQMKSVIEHDGVVGVAFDAWMMYPGWARGETDPNVVSIEAAADHIDYVCQMAGNTKHSAIGSDLDGGFGTEQTPGDLNSIADMQQLDGILSRRGYSDDDLNAIFHGNWMRTFRKLFGGCAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXD4</accession>
    <name>A0A518IXD4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_37680</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="160" mass="18029" checksum="C9603F5287413FB4" modified="2019-10-16" version="1">MSVSNKAKTVTINPAFLADVKDLHQELWDGLHALQEMCSLPISLEGKCFEFIGRLSDLRDKLAFQFSVEEAYGYFDDPAFCCPTFARRSGELLQQHRDLYMEIDSIAERAEQLLSVRDLAALTTIIPVAFDRFADKLQKHESAETQLMHDGLMQDIGGGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXD9</accession>
    <name>A0A518IXD9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_37650</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019600">
        <property type="entry name" value="Hemin_uptake_protein_HemP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10636">
        <property type="entry name" value="hemP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="64" mass="7128" checksum="FA61DC2C43AFBACB" modified="2019-10-16" version="1">MTNDSAPQDDAAAKEQELAAAALNLPKVIQFNDLPRCGDEVWITSDGQLYRLRKTRQGKLILTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXJ0</accession>
    <name>A0A518IXJ0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Carboxypeptidase G2</fullName>
            <ecNumber evidence="2">3.4.17.11</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">cpg2_2</name>
        <name evidence="2" type="ORF">Mal33_38200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.4.17.11" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="M20_dimer" evidence="1">
        <location>
            <begin position="203"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="408" mass="44449" checksum="530E04ECD68094E1" modified="2019-10-16" version="1">MNSSADRLNDACRWLESQKSVITQQLVQWAEIASGSHDTEGLQQMADRLRSDWQQHGLILQPTSLPSIEEIDSHGDILCWKTVDALVARQRPEAARRVLLAIHFDTVYERESSFRKCQWLDADRLRGPGVVDAKGGLLVMMWALAAIEKFDLAAEIGWTAILNPDEEIGSPASASLFQQQAGLHDFGLLFEPCLPDGAMVSQRKGSGNFTIVVRGRSAHSGRDPENGRNAIVLLSQVIGEVDRLNDPQADTTVNVGRIEGGGPLNRVPDLAIGRLNVRVSDASALADFENRLGQIVDQANEREGFEVRLHGGFHAPPKSVDDRTRKIQRAVEASLDTAAAAIRWQSTGGACDGSKLAFYGLPNVDTLGPRGGNLHNPEEWVDTASLVPKATSIVRLMTDYSRGVGPLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXJ1</accession>
    <name>A0A518IXJ1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sensor protein FixL</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">fixL_2</name>
        <name evidence="2" type="ORF">Mal33_38240</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004673">
        <property type="term" value="F:protein histidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PAS" evidence="1">
        <location>
            <begin position="3"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="128" mass="13995" checksum="D8121C1BB3F939D4" modified="2019-10-16" version="1">MKTDLDLAQFVQCVGDAIIAVDRRGEIILWNPGAVRLLGHSADEVLGKSMDFFIPHASRKPHWDGFHSAIASGQTHLGTNLIRVPALHKNGQTIRIALTVGILRDAEDQIEAIGAIIREDLQAPKQTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXK5</accession>
    <name>A0A518IXK5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative metallophosphoesterase YhaO</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">yhaO_1</name>
        <name evidence="2" type="ORF">Mal33_38370</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00840">
        <property type="entry name" value="MPP_Mre11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041796">
        <property type="entry name" value="Mre11_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos" evidence="1">
        <location>
            <begin position="6"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="419" mass="45355" checksum="1469E4BB5B859DCD" modified="2019-10-16" version="1">MTGESFRFIHASDFHLERPLGDLDEVPQHLREAMAGAAWKAAATVFETAVLENVDFVLLSGDLFHPITAGPRGMAMLVEQFEQLHQQNIQVFWTTGQVDDLAKLGDGLALPPNVTVFPRDRSEQAYVRRAGDTIAVVVGRSNDGRSGLHVPSFRHDPVEEFTIALGYGTSDATALAEGRFDYWALGGEHQRRTLDGAAGVGASYCGSPQGRSLSETGAHGFHLVDIDADGSSRVHFIESDSFRYVNVELGGADLGTASDLRSLLSQRIARLQHEHGDRHLLVGWEIHLGADSPMGAGDPTELLSWLRREFGHGSPAAWSVKLDVIAPPQFPQSWLEEDTILGDFLRAAGTHRKTGGRDLQLASLTEEHPGLAPAMEAALVEADPASRAATLDHATLLGVELLRGGKPRLAMVGDGKEYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXM6</accession>
    <name>A0A518IXM6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">4-diphosphocytidyl-2-C-methyl-D-erythritol kinase</fullName>
            <shortName evidence="8">CMK</shortName>
            <ecNumber evidence="2 8">2.7.1.148</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7 8">4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 11" type="primary">ispE</name>
        <name evidence="11" type="ORF">Mal33_38410</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>4-CDP-2-C-methyl-D-erythritol + ATP = 4-CDP-2-C-methyl-D-erythritol 2-phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18437"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57823"/>
            <dbReference type="ChEBI" id="CHEBI:57919"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.148"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 3/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the GHMP kinase family. IspE subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.148" evidence="2 8"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00056">
        <property type="reaction ID" value="UER00094"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050515">
        <property type="term" value="F:4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019288">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.890">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00061">
        <property type="entry name" value="IspE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013750">
        <property type="entry name" value="GHMP_kinase_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036554">
        <property type="entry name" value="GHMP_kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006204">
        <property type="entry name" value="GHMP_kinase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004424">
        <property type="entry name" value="IspE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43527:SF2">
        <property type="entry name" value="PTHR43527:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08544">
        <property type="entry name" value="GHMP_kinases_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00288">
        <property type="entry name" value="GHMP_kinases_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF010376">
        <property type="entry name" value="IspE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55060">
        <property type="entry name" value="SSF55060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00154">
        <property type="entry name" value="ispE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="5 8 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GHMP_kinases_N" evidence="9">
        <location>
            <begin position="110"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="domain" description="GHMP_kinases_C" evidence="10">
        <location>
            <begin position="239"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="16"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="159"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="117"/>
            <end position="127"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00032554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QDV57826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="320" mass="33757" checksum="DB5561435DB56690" modified="2019-10-16" version="1">MHANQPQAVEINTPAKLNLFLELLDRRADGFHKLETVMVAINRFDRIRVALSDSADVRVECGWLPHQAAVVERYRGSQAVAALPRSQDNLVTRALEQFRQRFSIADGFRASIAKTIPAGAGMGGASSDAAGALRAAAQLCQIDQHDQRLLQLAGELGSDIPFFFGSPQGAMSAAIATGRGERIDPVSIGGKLHFVVVHPPESVSTAEVYRRCQVPSRPSSAAAMLAALVGGRGTQIASQLLNRLSEPARATSEWIDRVLSAIARTPVLGYQVTGSGSACFGVCPNAAVASRIAHNLQAAGIGSAFAAHSVCIASPTRDMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXN5</accession>
    <name>A0A518IXN5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Translation initiation factor IF-1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2 5" type="primary">infA</name>
        <name evidence="5" type="ORF">Mal33_38670</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the IF-1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04451">
        <property type="entry name" value="S1_IF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00075">
        <property type="entry name" value="IF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006196">
        <property type="entry name" value="RNA-binding_domain_S1_IF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004368">
        <property type="entry name" value="TIF_IF1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33370">
        <property type="entry name" value="PTHR33370"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01176">
        <property type="entry name" value="eIF-1a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00008">
        <property type="entry name" value="infA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50832">
        <property type="entry name" value="S1_IF1_TYPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2 3" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="2 3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="S1-like" evidence="4">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV57852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="73" mass="8372" checksum="60F2739A429E0178" modified="2019-10-16" version="1">MAKNEEAFEVEGTVTQALANTRFRVQLETGSEVLAHVAGRMRKHFIRIVPGDKVRVELSPYDLTKGRIVYRER</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXW6</accession>
    <name>A0A518IXW6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Linear gramicidin synthase subunit B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">lgrB</name>
        <name evidence="3" type="ORF">Mal33_39430</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
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        <location>
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        </location>
    </feature>
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        </source>
    </evidence>
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            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="QDV57927.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1133" mass="124811" checksum="A326E16596B6A500" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXY2</accession>
    <name>A0A518IXY2_9BACT</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
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        <name evidence="2" type="ORF">Mal33_39600</name>
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        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
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            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
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        </location>
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        </location>
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        </source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="895" mass="97897" checksum="D31FEF24D86E1D2B" modified="2019-10-16" version="1"> </sequence>
</entry>
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                <person name="Boedeker C."/>
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                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
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                <person name="Storesund J.E."/>
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                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
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    </dbReference>
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        <source>
            <dbReference type="EMBL" id="QDV57969.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="256" mass="27692" checksum="4B4FCC7310A80EF6" modified="2019-10-16" version="1">MKLKDKTIMVTAAGRGIGKGCAVELARAGATLIINDRPGSQDLKPTVQELRDQGANVKGVEADVFTRSGCEDLLRKAVEQSGPVHGLVSCPAYQKVSPFLDLCPDDFERVIQGTLFSGFHMSQLVARQMVDEGIAGKLVFISSVLAQRPMAQKSAYCAAKAGLNQLAKTIAVELASRHINVNVIEPGWIDTPGEREAFTPKFFEEEAPKLPWGRLGTARDIGRAAAFLMSPNADYITGSVLPVDGAFRYRDGRMLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
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    <name>A0A518IY17_9BACT</name>
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        <submittedName>
            <fullName evidence="2">BNR/Asp-box repeat protein</fullName>
        </submittedName>
    </protein>
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    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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        <location>
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            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021875799" evidence="1">
        <location>
            <begin position="24"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="389" mass="42968" checksum="528600FFBE07EAAC" modified="2019-10-16" version="1" precursor="true">MKVVAFPLAVLLAFAATASRVGADDPLTAVTLETIDLTDQLRRQVVVDRETGLYLGYPTTALLDDGQSMLCIYAKGRGRGALLYKRSEDGGKTWGPRLDTPENWSTSKGVPNLHRVIDAEGKRRNLLWAGMYPARTAVSDDEGKQWSELKSAGDWGGSMVMGCVEALNTKGHYLAMFHDDGRYFTERGGSTETVTVYKSLSTDGGLTWSRPEAVFRSDEIHLAEPACIRSPDGKRLAVLLQESRLRKNSHVMFSDDEGKTWTQPRELPLALTGERHVARYDSDGRLMVSFRCRSPYRSANTRPFEGSWVAWVGTWDDIANGKQGQYNVCLKENTKGYDTGYSGVELLGDGTFVATSYGHWDEGLDPYILSVRLKLAELDGMSKGLAASE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IY48</accession>
    <name>A0A518IY48_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_40230</name>
    </gene>
    <organism evidence="1 2">
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        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
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                <person name="Bruemmer F."/>
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                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
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        <property type="entry name" value="AtuA"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="614" mass="65956" checksum="31123791BBB2376D" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IY57</accession>
    <name>A0A518IY57_9BACT</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
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        <name evidence="2" type="ORF">Mal33_40350</name>
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    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
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        <property type="entry name" value="DUF1501"/>
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        <property type="entry name" value="TAT_signal"/>
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    <dbReference type="Pfam" id="PF07394">
        <property type="entry name" value="DUF1501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="474" mass="53051" checksum="DEE5C3385D9D5DE2" modified="2019-10-16" version="1">MNAFNNCGLSRRELLCRSGMGFASLALADLMHGEAVADSVANPLLPKPPQFPAKAKRVIHLFMNGGPSHVDTFDPKPELQKRSGQPLDGGNLKTERPTGALMGSPFKFQRYGESGIEVSELFKETAKSIDDIAVIRSMHANVPNHEPSLMLMNTGESRLIRPSVGSWMTYGLGTENQNLPAFVSMCPGGYPIKGAQNWQSGFLPGIYQGTYVDSNNTRIEKLIENINNFRVSRDDQRQQLDLLNQLNGIHRSTRTSEPKLESRIQSFELAYRMQADAAEAFDINREPQHILDMYGKGVHARQTLIARRLVERGVRYVQLWHGAGQPWDNHDDLETRHRALAGQCDQAIGALLRDLKQRDMLKDTLVIWGGEFGRTPVVEMPKEGTNQGKMNGRDHNHHGFTVWMAGGGVKGGYVHGSTDEFGFKAVENRVHVHDLHATMLHLLGFDHKKLTYRYAGRDFRLTDVHGRVIDELIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYF1</accession>
    <name>A0A518IYF1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ECF RNA polymerase sigma factor SigE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">sigE_5</name>
        <name evidence="4" type="ORF">Mal33_41330</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
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        <property type="match status" value="1"/>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="36"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="3">
        <location>
            <begin position="137"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV58116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="201" mass="22771" checksum="04B036E7D6B16A04" modified="2019-10-16" version="1">MNVQNHSKPADEAVEASDDALIGRALAGEPAAYDSLVRRHAGRLLTMIRAQVGNRDDAEDLMQETLAQAYFKLDTFAGKSSFFTWMYRIAFNLTITKRRKRRLESTHTRTNIETAPAPEDPAVAVDQRMADAEQIARLRSAIDRLEPSRRRVLVLRDIDGLDYGEIAEILAIPKGTVRSRLHRARLDLRDLLSRDETIDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYF5</accession>
    <name>A0A518IYF5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
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    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
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    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="124" mass="13696" checksum="49C7EDBE22F3F62A" modified="2019-10-16" version="1">MSEPISSSPNSPTPDSERKHPIDAVHFVHHAIKHAIRDAAAQHSGKVSGEGLCRILLELAVDEFGGEGANVLKQWNIQTSDDVGLIVVRMQAAEIDEANRVDQDSNFGGWFDLDQPAEQWNLKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYH1</accession>
    <name>A0A518IYH1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Heme A synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ctaA</name>
        <name evidence="8" type="ORF">Mal33_41540</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016653">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006784">
        <property type="term" value="P:heme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003780">
        <property type="entry name" value="COX15/CtaA_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02628">
        <property type="entry name" value="COX15-CtaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="34"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="67"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="95"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="120"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="150"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="187"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
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            <begin position="224"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
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            <begin position="257"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="305"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV58137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="343" mass="37968" checksum="7731F90F75DAA6EA" modified="2019-10-16" version="1">MNREQEPILDELKNETPATDEAGSPWRSPWVHRWAVLLVCLTWPLIWVGGLVTTYDAGMAVPDWPATYGYNMFLYPWTTWLLGPFDLLIEHGHRLLASLVGLITIAMLVAAVWSRQPRWIVRLCIVALVGVILQGALGGARVVMDARTVAMIHGCFGPAFFVLCWMIAGVSSRWWQATDAPSVPRTAVRWGAALAISSYVQLILGAQLRHMPVDAGDSFFRHIVFSHLTGAALVAVLSVITAWKLRRCGDLTLSRIGLGLIGLLILQWSLGLGTWFVNYGSPWALSQWPSLARYVIVAKGWTESMIVTGHMATGSLILALACWTWLRASRRCENSSFAKPAFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYM4</accession>
    <name>A0A518IYM4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ubiquinone/menaquinone biosynthesis methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_42080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="Methyltransf_25" evidence="1">
        <location>
            <begin position="64"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="267" mass="29525" checksum="EF70946D698BF21A" modified="2019-10-16" version="1">MQIESIPSWQLPAGVSPGTWDYAARPAIATEYDQYFADHPLFALDQQLVLQHLPSPDSQGRATVADLGCGTGRALVALAASGYRGLAIDLSQHMLEVVQQKTQTQALPIASVRANLVDLNGIADNCVEHAVSLFSTLGMIRGRANRIAALGHTRRILKPGGKFVLHVHNIWSSLYDPAGLRWLCRSWWSGRKRGDQEFGDRVYQYRGLPNMFLHNFGLSELKSDLRQAGFEVEQIFPLNLTASGVLPLRRVLPRVRAGGFVAVCRRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYN9</accession>
    <name>A0A518IYN9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SHD1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_42110</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008092">
        <property type="term" value="F:cytoskeletal protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025574">
        <property type="entry name" value="Nucleoporin_FG_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007131">
        <property type="entry name" value="SHD1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13634">
        <property type="entry name" value="Nucleoporin_FG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03983">
        <property type="entry name" value="SHD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SHD1" evidence="2">
        <location>
            <begin position="586"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="281"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="402"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="553"/>
            <end position="582"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="653" mass="65515" checksum="E810816B2FA07AC3" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYQ7</accession>
    <name>A0A518IYQ7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">UDP-glucose:undecaprenyl-phosphate glucose-1-phosphate transferase</fullName>
            <ecNumber evidence="9">2.7.8.31</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">wcaJ_2</name>
        <name evidence="9" type="ORF">Mal33_42250</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bacterial sugar transferase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.31" evidence="9"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003362">
        <property type="entry name" value="Bact_transf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017475">
        <property type="entry name" value="EPS_sugar_tfrase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02397">
        <property type="entry name" value="Bac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03025">
        <property type="entry name" value="EPS_sugtrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="78"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="112"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="145"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="172"/>
            <end position="192"/>
        </location>
    </feature>
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                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
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    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
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        <location>
            <begin position="36"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="440"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="466"/>
            <end position="489"/>
        </location>
    </feature>
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            <begin position="210"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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            <begin position="753"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="213"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV58344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="777" mass="85892" checksum="C3F8A3FC190C307E" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
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    </dbReference>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="75" mass="8683" checksum="387F0A5D21827BAE" modified="2019-10-16" version="1">MDKEINVLALVKGEEKFIFLYDDANRTETLRLLGRFAADPEIDFSWYDAAVLSKRIRDSIPAVVEEEPIHRRFAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZF9</accession>
    <name>A0A518IZF9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">BNR/Asp-box repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_45000</name>
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    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
    <dbReference type="SUPFAM" id="SSF50939">
        <property type="entry name" value="SSF50939"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="430" mass="48399" checksum="1600FA8AC68A07B0" modified="2019-10-16" version="1">MNHIPDPQRQLGPSRRKFLAASAAATSCLMLPADNNLRADTEGVRSTDHFWYRLAPEGPYIDSQRDNKAFGFGLGKVYLSEDNGKTWAHDAIFRNADNITFSVILKNGNILFATRTKLYLSTDNLKTYKQITVKNSDGSDYLPHTPIDPANPGWYFHSLDGVHTWDVDGSEMLVWGNYCNVMGGAVPVNIYYSTDQGETVKLAYSFGQNPSFQQKGGDKSDWVGDPSNPVICRHVHTVAYNPVENAFYACTGDHDRVIDGKAQQECHWLRGTYDAAKDTWDWKVLVSVNSNSRYKSGGINFVDGQLYWASDANGNNGTMPHDRGIFRCDPADIADPSKHTMLFNPHYESANMIIEDDVFLSAHYGPASPFNTGFIISTDRGKTWAEYDLPQFGKRSPLRFHKKNSDGWFRVDLRKGWIERGEVLFIKPKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZG2</accession>
    <name>A0A518IZG2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">FtsX-like permease family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Mal33_45030</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="348"/>
            <end position="366"/>
        </location>
    </feature>
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        <location>
            <begin position="19"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="7">
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            <end position="375"/>
        </location>
    </feature>
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        <source>
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        </source>
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    </evidence>
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            <dbReference type="ARBA" id="ARBA00022989"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
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    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
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        </source>
    </evidence>
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            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV58480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="384" mass="41096" checksum="323B6180132E76FA" modified="2019-10-16" version="1">MLLPWEYGVRNLARRPVRTGLTLLALATVVMLVFVVVGFIRGLEQSLSVSGDDDVVLVYSVNSEENIENSSIAARSPALLSASLGGTWKRFGVDHVSPELYLGTRVSTSDQENGLGLVRGVTYRAPLVRRNVKIIDGAWPEQNEVIVGRLASAKLGSHSDALAIGQTIQFEGETWTVSGHFAADGAAYESEIWCDLSAFQTVTKRQDLSLVAMLLAPGASAAEIELFCKERTDLELRALRESDYYASLQQHYRPVRLLAWFVVALVSGAGVFAGLNMMYGAVAGRIRELATLQALGFRRRAILLSLVQEGVLLAAAASLLSGVIALTMLNGLAVRFTMGAFTLRIDSVAILVGCGVGLLLGVLGALPPALKALRESVAISLKAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZG6</accession>
    <name>A0A518IZG6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter ATP-binding protein YtrE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ytrE_2</name>
        <name evidence="5" type="ORF">Mal33_45060</name>
    </gene>
    <organism evidence="5 6">
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        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="4"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="40"/>
            <end position="47"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV58483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="229" mass="25030" checksum="04F92EBC90E326DB" modified="2019-10-16" version="1">MTLVELKNVSKSFSKGDETITPLDDVSLQIDEGEFVSLMGPSGTGKSTLLNLVSGIDRPDSGTIIVDGTEVTRLSRGQLADWRAANLGYIFQTHNLIPVLTAYENVELPTMLLKLTRAQRRQRVELALEAVGLADRSDHYPRQLSGGQEQRVGIARAIVAHPKVVVADEPTGSLDTQTSEQIQSLLQRLNRELNITMLMVTHDSDVAAIASRQLVLDRGKFIESQAATV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZS4</accession>
    <name>A0A518IZS4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Arylsulfatase</fullName>
            <ecNumber evidence="4">3.1.6.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_46110</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="PTM">
        <text evidence="1">The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.</text>
    </comment>
    <dbReference type="EC" id="3.1.6.1" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004065">
        <property type="term" value="F:arylsulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021881332" evidence="2">
        <location>
            <begin position="45"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase" evidence="3">
        <location>
            <begin position="50"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="modified residue" description="3-oxoalanine (Cys)" evidence="1">
        <location>
            <position position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR600917-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV58588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="503" mass="56601" checksum="4C1D211D6F7BE231" modified="2019-10-16" version="1" precursor="true">MSVFADACGYGLNDSIDNRTITMKATSLFLLSMLLIFFSSPAQAAEAHQPNIVFILVDDLGWSDLHCYGHRYHHTPHLDRLASEGLRFTAGYSPAPICSAARASILTGKTVGRLGFEFVTKNTPGRQSLDIDVPLLTPELTLNLPTAEVTIAERLAAVGYQTAFFGKWHVSQHYQRRYLAWHPDFGPKQQGFAVAGEDFGDHPYAWDKKHPPSPAPGGVFPRDSMIQRTADFIRRQADATKPYFLMASSFYVHTPVKTRCRWLVEKYERHLPPDAKHRRQRLEYAAFVETLDHHVGTIMDAIDQSGQRENTLVFFMSDNGGHPEYCANAPLRGSKWNLYEGGIRIPMIARWPGKIDAGVTSDTPVIGYDLSPTFVSLAGGDARGVDGIDMQRVLREPSWKPDRHLLWHFPYYHPEKTFSKAIDKIGVDDFTTSKTRPQSALRKGNYKLIHFAEDDRVELYDVAADISEANDLSQSHAEIAAQLRETLQQQLDAMNARRAVAWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J048</accession>
    <name>A0A518J048_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MerC mercury resistance protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_47480</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015097">
        <property type="term" value="F:mercury ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004891">
        <property type="entry name" value="Mercury-R_MerC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03203">
        <property type="entry name" value="MerC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="214" mass="22267" checksum="CA4C37335796B762" modified="2019-10-16" version="1">MDDVMQPTSIGPRGSESRLADSSSATFEWRDWIGIVASIGCAIHCAAMPFVIAFLPALGLSFLADEGFHRWMALACFVIALAAFVPGFRKHRRWTPGAIAIVGLSLITFAAFGFAGDCCAACESPAGTEVAATACADACCEHCAVNATAETKSSNPSSASFVTASVVSPNFLTGIAPWITPLGGILLVSAHLLNRRYGCLCGCCEAKPATKVAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J049</accession>
    <name>A0A518J049_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_47460</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="136" mass="14882" checksum="3ABD342B0109FB54" modified="2019-10-16" version="1">MFRLSLLTAVFVGLLGAQLRGDDPSALLIATSHQRTASSLPPLPHGSRVVVLIQKSEDDYATVNARALTARNATHIVFDRADQSPLIQMFRERLTRRGAIPVELREPWTQPLGLETSIADASTLSTFANFFAGPQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J050</accession>
    <name>A0A518J050_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative HTH-type transcriptional regulator YtcD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ytcD</name>
        <name evidence="2" type="ORF">Mal33_47420</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002577">
        <property type="entry name" value="HTH_HxlR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01638">
        <property type="entry name" value="HxlR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51118">
        <property type="entry name" value="HTH_HXLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH hxlR-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="79" mass="9036" checksum="F9E88A56A264AAA1" modified="2019-10-16" version="1">MFGCVTQRMLTKQLRELEASGLVNRMVYAEVPPRVEYELTEEGKSLQPVLELLKKWGEEHAMELISERQKSAVDGQATE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0K1</accession>
    <name>A0A518J0K1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_49010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="169" mass="18909" checksum="50DFF8D77A7B455F" modified="2019-10-16" version="1">MHALVLSNPKVARMKTFLQITLCVIVATGWSYGGQSLDDVGTSANGSDKTTAFDAALGAQPKLLRISGRFDGSGRIRFTRRVVRYEHKSWQPPSRVLFDGEPWTKLDRTPAPWRDFGARLDLSKAWIVKRKGRDVIALEHTPDGFDLYVCDSPNGSDDYSVMLAIPRRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0M6</accession>
    <name>A0A518J0M6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_49180</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008551">
        <property type="entry name" value="TANGO2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17985">
        <property type="entry name" value="PTHR17985"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05742">
        <property type="entry name" value="TANGO2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="258" mass="28282" checksum="71FAE3F1DC285C75" modified="2019-10-16" version="1">MCLLALQYQLVPESPVLVAANREEYFDRPSLAPSIQSGKPRVLCGIDQRGGGTWLGVNQNGMFVGICNRATVTPLFGQRSRGLLCLDLLRCGSSRKALEKVQSELSKTRYEGCNIMIADANAGFAIHSEEEHEVVELVEGLNIIGSRNLNDPTDERVAMARRLLTLQTLDSPVKFLAVASKVFARTPTLPGRPSMVVRGNDYGTVSSTLLSLGVKPRDAIYQFSTGAPDQAKYEDYSPLLRDILSRGLREARTKAQRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0N0</accession>
    <name>A0A518J0N0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/beta hydrolase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_49130</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022115724" evidence="1">
        <location>
            <begin position="26"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S9" evidence="2">
        <location>
            <begin position="195"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="683" mass="75202" checksum="26458EA2835C0D54" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0V8</accession>
    <name>A0A518J0V8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein-tyrosine-phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_49600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein-tyrosine phosphatase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.48" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016311">
        <property type="term" value="P:dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022778">
        <property type="entry name" value="CDKN3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05706">
        <property type="entry name" value="CDKN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="SSF52799"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TYR_PHOSPHATASE_2" evidence="3">
        <location>
            <begin position="99"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009580"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV58935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="186" mass="20494" checksum="6822E90E7878D808" modified="2019-10-16" version="1">MKIPSVFDKPVKPTPCSRTYWVLDGALLAGAYPGRPDPAEHQQRLQSLFDAGMRTFINLQEEGETNNSGKPFVRYDNGLRELAGGEFAHLRFPIPDGGTTTVDRMRSILDAIDVSLAADRPVYVHCFGGMGRTGTTVCCWLLRHGLTTSANVLDLLTQLRQADVQRASWKAPENASQEAFVLSWTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J187</accession>
    <name>A0A518J187_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_51000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="53" mass="6214" checksum="739C5D97177FA932" modified="2019-10-16" version="1">MMWGRMICSDDKMVVLAQTLIVLESDQRMKRMVRELVFGGWQEILQNADDGIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1G1</accession>
    <name>A0A518J1G1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SGNH_hydro domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_52120</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SGNH_hydro" evidence="1">
        <location>
            <begin position="73"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="223" mass="24472" checksum="82C2AF6BA44057E8" modified="2019-10-16" version="1">MILSPRRIVALAILFVVGGISVAEAQQKESRWEKTIAGFEAVDAKNPPQPGGIVFTGSSSVRMWDLKKSFPELQLVNRGFGGSEIADSTEFAPRFLIPHKPRQIVLYAGDNDIAKGKDAAAVIEDFQQFVNTISTALPETKIAFLAIKPSISRWKLWPTMKAANEGIAAICEADPKLDFIDISPDMFGDDGKPDPALFAKDGLHMTPAGYERWTARVRKTLGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1N3</accession>
    <name>A0A518J1N3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 2">Hypoxanthine phosphoribosyltransferase</fullName>
            <ecNumber evidence="1 2">2.4.2.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">hpt</name>
        <name evidence="4" type="ORF">Mal33_52700</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>diphosphate + IMP = 5-phospho-alpha-D-ribose 1-diphosphate + hypoxanthine</text>
            <dbReference type="Rhea" id="RHEA:17973"/>
            <dbReference type="ChEBI" id="CHEBI:17368"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="EC" id="2.4.2.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Purine metabolism; IMP biosynthesis via salvage pathway; IMP from hypoxanthine: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the purine/pyrimidine phosphoribosyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.8" evidence="1 2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00591">
        <property type="reaction ID" value="UER00648"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052657">
        <property type="term" value="F:guanine phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004422">
        <property type="term" value="F:hypoxanthine phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032264">
        <property type="term" value="P:IMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006166">
        <property type="term" value="P:purine ribonucleoside salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005904">
        <property type="entry name" value="Hxn_phspho_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01203">
        <property type="entry name" value="HGPRTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0660">Purine salvage</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pribosyltran" evidence="3">
        <location>
            <begin position="51"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU364099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV59242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="233" mass="26602" checksum="249DD71B8DE8EB66" modified="2019-10-16" version="1">MPESILAASHRFFNQLVQPWGNMLRCRRVPWPARIPPDITAFSHPRLLNMKTLLDEQQLERGVSELAQRINDHYGSRPLTVVAVMTGSLILLADLIRRLNMPIRVGVVQASSYRGGTRSGELLVNAAMLINIRDREVLLIDDIFDTGRTLERLLEDMRQMGAQDVKSAVLLQKNRQHDVQVRPDFVAFEIPDEFVVGYGLDYEDMYRNLPYLGVLEQADLDRHHALHGPAIDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1N8</accession>
    <name>A0A518J1N8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Lar_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_52770</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050043">
        <property type="term" value="F:lactate racemase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043166">
        <property type="entry name" value="LarA-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018657">
        <property type="entry name" value="LarA-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09861">
        <property type="entry name" value="Lar_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lar_N" evidence="1">
        <location>
            <begin position="25"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="409" mass="44130" checksum="A826F67967544A6F" modified="2019-10-16" version="1">MSTPEPHRFWQDGPLAIHGGCEAEVLTLAPVDLQALPDPRRSIRDALQHAEDYPPIHQAIVPGDRIAVVVDPNLPSLFDCVAGVLDAIASDANGEIEVVLGEDASEATLQRLTEVVGNQAKVHRHDPDDQATLGYLAASEAADPIYLNRMILEADFVIPLAIARPDGALDPRCEAGGVFPQFADRRSQQRVRDAQFFGRPSEAAPNTARKQADEAAWLLGIQMVVEVLPTVDARAAEIVAGTPGGVRRKLTSSIESSWQRSAPNPPSLVIACIDGDDQQQNWNNVARALHVARGLVEVGGAIAICCDLTDTPGPALRRLASDASYEDLQKATRKDLTREGMIANVLLRAREESRIVVASGLPREPLEEMGLGAIETREQLQNLVDQYSHTVVVRAAQFCVATVGEADEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1S8</accession>
    <name>A0A518J1S8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_53180</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="54" mass="6015" checksum="C143491709315D8F" modified="2019-10-16" version="1">MVDYEPAAIPNRRLVSPKIVGEIPSRVLIGMPRSRFGLVKHNKLLPSTVTPLSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1Z4</accession>
    <name>A0A518J1Z4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Arylsulfatase</fullName>
            <ecNumber evidence="8">3.1.6.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">atsA_38</name>
        <name evidence="8" type="ORF">Mal33_53790</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="PTM">
        <text evidence="3">The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the sulfatase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.6.1" evidence="8"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004065">
        <property type="term" value="F:arylsulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032506">
        <property type="entry name" value="DUF4976"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024607">
        <property type="entry name" value="Sulfatase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16347">
        <property type="entry name" value="DUF4976"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00149">
        <property type="entry name" value="SULFATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021877747" evidence="5">
        <location>
            <begin position="21"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase" evidence="6">
        <location>
            <begin position="24"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4976" evidence="7">
        <location>
            <begin position="393"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="501"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="modified residue" description="3-oxoalanine (Cys)" evidence="3">
        <location>
            <position position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR600917-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF16347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV59351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="524" mass="60347" checksum="D2F9CBF5627F33E2" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J2B8</accession>
    <name>A0A518J2B8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4832 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_55120</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032267">
        <property type="entry name" value="DUF4832"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16116">
        <property type="entry name" value="DUF4832"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021965813" description="DUF4832 domain-containing protein" evidence="1">
        <location>
            <begin position="29"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4832" evidence="2">
        <location>
            <begin position="277"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV59477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="472" mass="53004" checksum="1E4F611A51C11018" modified="2019-10-16" version="1" precursor="true">MTRTRPFASLPFSIALLLLAAFTSPAIAQPTAAWRFTPADFSYSPGPADNPLKGLVPYQDPPADRFPYSMEFNYLPLAKLVTGPGQYDWQPMDAMLEDIASRGRQTVVRVFLEYPGRKNLIPQFLIDGGLKVHYYMNTNTAPHPPAAIETPDYEDPNLRKTMTDFIAAWGARYDGDPRLAYITAGLLGTWGEWHTYPKTELWASKQVQREILDAYVAAFPKTPVLLRYPAGPDDELYYDSTIYPFGYHDDSFAHSTLPTGRKQDDWYFWPKMLHAGLSQRWQTAPIGGEIRPEVWGCCFDKEPCTAASQSFDECRDVTHATWMMDTGLSRKKADADRYRRAIEAVQKMGYDLQVVDAAAKRQPDGSVKVQVTVENRGIAPFYHHGWTARLQIASDQKLIGELATDWSPRMIQPGERKTFEHTLDPTKLPAGKHQLQLQIPNPMPSGKPLRFANQAVDPRSGALTLGTFAVAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ILY6</accession>
    <name>A0A518ILY6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Tad domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_00160</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028087">
        <property type="entry name" value="Tad_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13400">
        <property type="entry name" value="Tad"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="domain" description="Tad" evidence="2">
        <location>
            <begin position="24"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="500" mass="52263" checksum="8B070E9315142E65" modified="2019-10-16" version="1">MNTHAKQPSSLPARQIKPAARTGKVFVFLCVALPGVFAVLALVFDAGLMMTASRDYQNTTDAAAYAAATWTMMGGDENSINTISSEYVQSHNALPGANVTTNSPPSSGPYQGVAGFSEVIVQGESPSYFLQRFAAGGQQSITTRAVAGTKTATSPAAIMLLDADPAPITVASILSLPLYPSLLGGLEVLGLGSLTVDGAVLSNNTWGGVDEYGEKAGESHGPPYSIACTPLVPLTALRASDIRTAGGVDRLLHYDALPGLGALNLRANRMPMPDPMGNLAPPSTASDPDNVEVDDHGGVMVTLNILKPFGTVLEPGVYDWIDVTAGIARFEPGVYIIRGKHPITGIALGITGGIVYADGVMFYVTSNSNYDPASGLPDAVENREVAPPNTIGAQLPSVLISPLPGSRLSGLNDPSSPYHGMLVYQRPRDRRPITILSLQTLGITQFSGTVYSRWGHAILAGSGTFNSSFAVGTMRVVTLGNISLRPSGYFPAASDVYLVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IM91</accession>
    <name>A0A518IM91_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CsbD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_01570</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0337 (CsbD) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008462">
        <property type="entry name" value="CsbD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036629">
        <property type="entry name" value="YjbJ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05532">
        <property type="entry name" value="CsbD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69047">
        <property type="entry name" value="SSF69047"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="107"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="CsbD" evidence="3">
        <location>
            <begin position="6"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV54208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="142" mass="15831" checksum="C570DAF212F4A1FB" modified="2019-10-16" version="1">MATKQQISGEWNSIQGAVKEKYGQITDDELREVEGEKEQLIGLIQQKVGAARAEVESFVNKIYQECGESCSHLSDRAANYAEATGQRLREGYDQSTRAVARRPMESIVTAFGVGVLAGVAIGYSLAADRYREPTWRDRLMNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMC0</accession>
    <name>A0A518IMC0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Helicase Cas3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Mal33_01900</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the central section; belongs to the CRISPR-associated helicase Cas3 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051607">
        <property type="term" value="P:defense response to virus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3210.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035011">
        <property type="entry name" value="Cas3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006483">
        <property type="entry name" value="CRISPR-assoc_Cas3_HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038257">
        <property type="entry name" value="CRISPR-assoc_Cas3_HD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013444">
        <property type="entry name" value="Helicase_Cas3_CRISPR-ass_Anaes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24031:SF539">
        <property type="entry name" value="PTHR24031:SF539"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18019">
        <property type="entry name" value="HD_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02621">
        <property type="entry name" value="cas3_GSU0051"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01596">
        <property type="entry name" value="cas3_HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51643">
        <property type="entry name" value="HD_CAS3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0051">Antiviral defense</keyword>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 11" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD Cas3-type" evidence="10">
        <location>
            <begin position="857"/>
            <end position="1051"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="598"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="634"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="688"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="603"/>
            <end position="624"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QDV54240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1387" mass="153994" checksum="4BF0DD99ECBDB029" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMC2</accession>
    <name>A0A518IMC2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">3-phenylpropionate/cinnamic acid dioxygenase ferredoxin subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">hcaC</name>
        <name evidence="6" type="ORF">Mal33_01640</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008942">
        <property type="term" value="F:nitrite reductase [NAD(P)H] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042128">
        <property type="term" value="P:nitrate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012748">
        <property type="entry name" value="Rieske-like_NirD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00355">
        <property type="entry name" value="Rieske"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="SSF50022"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02378">
        <property type="entry name" value="nirD_assim_sml"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
        <property type="entry name" value="RIESKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0534">Nitrate assimilation</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rieske" evidence="5">
        <location>
            <begin position="5"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV54215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="105" mass="11679" checksum="A75DBFDB1468A079" modified="2019-10-16" version="1">MSDFETVGKVEDFEDGKGQAIPVNGRMVAVFRVGEEFYAIDDLCPHMGASLAEGHVDDEKGVTCPWHAWRFCIKDGTWCDNPKVKTEAFEVRVVDGEVQVLVSDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMG2</accession>
    <name>A0A518IMG2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_02290</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="70" mass="7744" checksum="4AD968DED6E856B7" modified="2019-10-16" version="1">MATSTLLNSRNSRITESHSDTTLSDFEIAGRVSAIRSNWSAEERVERHVEAARRFDALLEALNLDATPVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMH7</accession>
    <name>A0A518IMH7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sodium Bile acid symporter family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_02340</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002657">
        <property type="entry name" value="BilAc:Na_symport/Acr3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004710">
        <property type="entry name" value="Bilac:Na_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10361">
        <property type="entry name" value="PTHR10361"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01758">
        <property type="entry name" value="SBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="87"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="121"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="152"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="185"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="209"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="274"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="304" mass="32033" checksum="D70856F0A2BB7AC5" modified="2019-10-16" version="1">MLCGYSLIAYFWPSGGIDPFVASKAWLSWMIAATMFALGSLLPEDEVRRLRRQLPQVCLGTVTQCLVMPLAALAVVRFGGLEGGYRLGVILVGCVPGAMASNVLTLAAGGNVSYSVSLTTMATLASPITVPWLLVLMAGISESEARIEPLSMMLTLASTVLLPVIAGFSLARWSPRFKAIAERGGPILANLVILWIIAVVVGLNRDRLALIPLSLLASLLVVNLVGYVGGYTAGALTRMDEPMRRALTLEVGMQNAGLGTMLAVGSFGDQFPEAAIPTAAYTFGCVFTGTILVSLWRPRSAAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMM5</accession>
    <name>A0A518IMM5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosomal RNA small subunit methyltransferase A</fullName>
            <ecNumber evidence="6">2.1.1.182</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">16S rRNA dimethyladenosine transferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">16S rRNA dimethylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 9" type="primary">rsmA</name>
        <name evidence="6" type="synonym">ksgA</name>
        <name evidence="9" type="ORF">Mal33_02760</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>adenosine(1518)/adenosine(1519) in 16S rRNA + 4 S-adenosyl-L-methionine = 4 H(+) + N(6)-dimethyladenosine(1518)/N(6)-dimethyladenosine(1519) in 16S rRNA + 4 S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:19609"/>
            <dbReference type="Rhea" id="RHEA-COMP:10232"/>
            <dbReference type="Rhea" id="RHEA-COMP:10233"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74493"/>
            <dbReference type="EC" id="2.1.1.182"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.182" evidence="6"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052908">
        <property type="term" value="F:16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00607">
        <property type="entry name" value="16SrRNA_methyltr_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001737">
        <property type="entry name" value="KsgA/Erm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023165">
        <property type="entry name" value="rRNA_Ade_diMease-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020596">
        <property type="entry name" value="rRNA_Ade_Mease_Trfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020598">
        <property type="entry name" value="rRNA_Ade_methylase_Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011530">
        <property type="entry name" value="rRNA_adenine_dimethylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11727">
        <property type="entry name" value="PTHR11727"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00398">
        <property type="entry name" value="RrnaAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00650">
        <property type="entry name" value="rADc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00755">
        <property type="entry name" value="ksgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01131">
        <property type="entry name" value="RRNA_A_DIMETH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51689">
        <property type="entry name" value="SAM_RNA_A_N6_MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 6 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1 6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="4 6 7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 6 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="rADc" evidence="8">
        <location>
            <begin position="35"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="28"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="76"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV54325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="303" mass="33909" checksum="75C361BB335DAA92" modified="2019-10-16" version="1">MVNRQTASYLTKRFQQTGMRPLSRFGQNFLIDLNLVDLIADSADIDDRDLVLEIGTGTGSLTSRLAARAAHVITVEIDTNLAQLAQEELEDLPNVTMRLHDALKNKNNFDPELLENIREEFDKLPAKRRRFKLVANLPYNVATPIISNLLRCDPIPDVISVTIQKELADRIVAPPGTKDYSALSIWIQSVASASIVRTLPPGVFWPPPKVTSAIIRIDTDANLRARIDDIDFFHEKLRALYFHRRKFLRSVVLSAMKGELDKAQVDAVLEKLGFSGEIRAERLTVAQTIELINELGTASAEAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMS1</accession>
    <name>A0A518IMS1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Decarbamoylnovobiocin carbamoyltransferase</fullName>
            <ecNumber evidence="6">2.1.3.12</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">novN_1</name>
        <name evidence="6" type="ORF">Mal33_03270</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
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                <person name="Pinto D."/>
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                <person name="Rast P."/>
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                <person name="Lage O.M."/>
                <person name="Pohl T."/>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="429" mass="47868" checksum="36CDD33BB9234A6C" modified="2019-10-16" version="1" precursor="true">MRSFFVAAMAIGLLMPCGMTVSAADVEEGYTSLFNGTDMTGWVKRGGSAEYHVENGAIVGKCVPNTPGNTFLCSEKEFGNFILKLQYKVIEAGNSGVQFRSAAREEGDRERVYGYQYEISTGGNTTGRIYDEGRRGHKHGIIWLDAYTPEDRLAAAQASYKKDEWNDLEIQCVGPSIKTWLNGKLVVDMFDSFSMKGFFGLQIHSGKAGSVAWKNIRVKDLGQSQWEPFFVKADDGSYQLADAKFVLPEEWSFTEEGVLHGVHAKSQGKDGLVISNKNYDNFIARVTYRMHGGNSALYFRAEETSAPWVLRGFQNEIANNSKDSALWHTAGIVDGKKIPGRGWVATNDEFIEKVRNKDDQWNTTCTAAFGDRLVQTLNGFCTSDFIDEASEKTGKLGLQMHGGTDCEMYFKDFEVMPITDDMKKLIERK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INN9</accession>
    <name>A0A518INN9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_06700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="387" mass="41355" checksum="D6057E3915580FB0" modified="2019-10-16" version="1">MQPEPPRPDDNASRDNAAADELLRVANDLGPVVVDPAGAASSEPPVSPEPSAAPEPTGSLIDTLLFGLSLPERSARTVSALVGGLASESAARLIPTAFRSSKSYRVFVQQSLDFVIHDVGGVVSHKPASEDAQAEGLVARQTVGGMLDFAGVATLHMSPMTVLAIISDVAYGSSTYMRQLSEELKRKGLIDQESTIDHVTDLIDALQETSVQGADALNAPPINLEGLQQTIDKTRAALNRIDPTTTIPQAEIKRIWQEMETAATKAETSVFDVATTMTMFSMNRLSLVSQGALSSVVVAGNLIDQHIVGHYADALTEIQVRGLWTTLAESSQPYLEAIWNNFDDTKSTLTQDLLNGTLIGKAWSGLIGWWRGADKNKTPPAEESQQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP15</accession>
    <name>A0A518IP15_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_07790</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008374">
        <property type="term" value="F:O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003386">
        <property type="entry name" value="LACT/PDAT_acylTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02450">
        <property type="entry name" value="LCAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="506" mass="56355" checksum="694A93B4E8C22CCF" modified="2019-10-16" version="1">MLLSPRYRSFIVSLGCLIAAIGCAGKRSAKDLGNIYDSLAQAPDYERNPVIVIPGILGSRLVEEESRRVVWGTIDSRSTNPNDPEIAALLASPMVEGAPLASLRDNVVSDGPLARLKIRFLGIPIQVNAYEDILVTLGVGGYRDPSREEVEYANDHYNCFQFDFDWRRDITESVVLLHEFIQQQAEISRENSKRRFGIDNPDIKFDIVAHSMGSLVLRYYLRYGTQPLPEDGSLPELTWEGAKYIERAIMIAPPNQGSTLTLKELLAGSKFSSFLPIYPPAVLGTMPAVYQLLPRTRTGLVVQKQDPSKTLDLFDPAVWEELEWGLTAPDQDELLQAMLPDAPDRETRVRIANEHRRKCLIRAKKLHAALDLPATPPPGLQLHLFAGSSEPTVEKMVVDMETGEFEFPYKVAGDGTVTRTSAIMVEEVPGQQPLPRIYPIAWNSKTFIPSDHLGLTRHPIFVDNVLSLLLESRDAADLAAIRSAYAIQSMRKADVPPPLEELPLIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPB1</accession>
    <name>A0A518IPB1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_08700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="113" mass="12601" checksum="4A95547ACE7E311A" modified="2019-10-16" version="1">MADLILRDVDPERLREEIVRDVLEAIRPLLRQPAPPDSCRCCSRAELAQILGWSIAKVDRRTVAGAIPSIMDDGRRIYVVDDVMEALKQATPEAEAKAAARQAAKRAKRQPKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPC2</accession>
    <name>A0A518IPC2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cadmium, zinc and cobalt-transporting ATPase</fullName>
            <ecNumber evidence="7">3.6.3.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">cadA_1</name>
        <name evidence="7" type="ORF">Mal33_09050</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.3.3" evidence="7"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019829">
        <property type="term" value="F:ATPase-coupled cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027256">
        <property type="entry name" value="P-typ_ATPase_IB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="SSF81653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="SSF81665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01525">
        <property type="entry name" value="ATPase-IB_hvy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="16"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="40"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="74"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="239"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="264"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="569"/>
            <end position="588"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV54939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="625" mass="66286" checksum="B2798FE445559D03" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPE7</accession>
    <name>A0A518IPE7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Helicase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_09080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase C-terminal" evidence="1">
        <location>
            <begin position="227"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="407" mass="44263" checksum="42E5CF63C7F5FBF9" modified="2019-10-16" version="1">MVLDSAFSTVSHCQNQVTSCGLGLADNFAPAAAAAEVLAAARLQPRAYQRRMVVAALQMIAGRQRAPDGHLAPAAGRVLVESPVGSGKTVIGLAIASALQRATGCRVGWAAMRRNSLARVAAENAFRVFNLDLQSISMFDKSPADVDLLVVDEVACGGTAQIERLHRQLHPRWTLGLAANSDPIKACFDRVIRDAGVSQLIADGYLSPYRHYTLDEYTPAVVAKRLIEEPDRWGQSLAFFQRRQQGLACAGLLQEQGIACELLGTGAHRERQLDAFERGNVRVLISTAAVPESIDCPDLKTVFCRPAGRSSMLDMAGPVFCKSVGQPIKQIVQCRQAAWPMWKSIPADEQFVGGQGGWRSVAVNRQLAQIVAPSDPLRLASEFPRQEDFFLGRERLRCANASRSVRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPI3</accession>
    <name>A0A518IPI3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AAA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_09740</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="1">
        <location>
            <begin position="173"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="443" mass="49849" checksum="DF1AF97F9A8787BB" modified="2019-10-16" version="1">MILVTVLNQTHSIDSALLSGLLGGDTFWPTEPRNLDETGLSESYIDALILKIFLNTGTLSGRAMAERTGIPFGVVEPLLEAQRTRQLITHVRPAAFNDYYYSLSENGQKRAQTHMSHCAYTGPAPVPLSDYVLSVEAQAAGLDPIGYDDLRGALSGISHNNELLDQLGPAINSNSGLFLFGPPGNGKTTIARCLTQCLGQEVWIPHAIFDDGNLIKVQDDAFHRPMPIPETGDGIIKAQQWDRRWIRIQRPTVIVGGELVMDNLEVRHDPRSNTCEAPLQLKSNCGCLLIDDFGRQRIQPEELLNRWIIPLENRIDFLTLPSGKKIELPFEQLIIFSTNLNPDQLVDEAFLRRVPYKIMVDDPDPKEFTRIFNHNVEKMGFAPAKGAAEHLLRFYEQSGRSLRRCQPRDILTQVNNFCKYKKIPPQLRPDFLDQACKSYFSEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPK0</accession>
    <name>A0A518IPK0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">Phosphoribosylamine--glycine ligase</fullName>
            <ecNumber evidence="2 7">6.3.4.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">GARS</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Glycinamide ribonucleotide synthetase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Phosphoribosylglycinamide synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 10" type="primary">purD</name>
        <name evidence="10" type="ORF">Mal33_09860</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>5-phospho-beta-D-ribosylamine + ATP + glycine = ADP + H(+) + N(1)-(5-phospho-beta-D-ribosyl)glycinamide + phosphate</text>
            <dbReference type="Rhea" id="RHEA:17453"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:58681"/>
            <dbReference type="ChEBI" id="CHEBI:143788"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 7">Purine metabolism; IMP biosynthesis via de novo pathway; N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-alpha-D-ribose 1-diphosphate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the GARS family.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.13" evidence="2 7"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00125"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004637">
        <property type="term" value="F:phosphoribosylamine-glycine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009113">
        <property type="term" value="P:purine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00138">
        <property type="entry name" value="GARS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020561">
        <property type="entry name" value="PRibGlycinamid_synth_ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000115">
        <property type="entry name" value="PRibGlycinamide_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020560">
        <property type="entry name" value="PRibGlycinamide_synth_C-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037123">
        <property type="entry name" value="PRibGlycinamide_synth_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020559">
        <property type="entry name" value="PRibGlycinamide_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020562">
        <property type="entry name" value="PRibGlycinamide_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43472">
        <property type="entry name" value="PTHR43472"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01071">
        <property type="entry name" value="GARS_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02843">
        <property type="entry name" value="GARS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02844">
        <property type="entry name" value="GARS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01210">
        <property type="entry name" value="GARS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="SSF51246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00877">
        <property type="entry name" value="purD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00184">
        <property type="entry name" value="GARS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="9">
        <location>
            <begin position="107"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV55018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="428" mass="45821" checksum="4DF323A6FF954576" modified="2019-10-16" version="1">MKVLVVGNGGREHALAWKIGMSPRVSQVFVAPGNAGTGVDATNVPISADDTEGLVNFARRESIDLTVVGPEVPLVNGLVDALEAAGLRAFGPSAAAAELEGSKVFCKNLLKAADIPTADYQTFRTGDDAARFIKDRYPEENSAVPVVVKADGLAAGKGVIVCSTREDALDAIDRITRQREFGEAGNELIIEDRLIGQEASILAITDGNAIVMLPAAQDHKPAYDGDKGPNTGGMGAYCPTPIVDEKMIEMIQEDIIVPTVHAMKRNRRPFKGVLYAGLMITSTGPKVLEYNVRFGDPECQPLLMRLKSDIMDILEAVADGRLIDIDPPEWDERPSICVVMASEGYPGDYVKGREISGLHDAAKLKDVKVFHAGTKLTQGSVQTDGGRVLGVTALGNSISNAKLQAYTAVKQIRWPGAWCRKDISDKAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQ63</accession>
    <name>A0A518IQ63_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Outer membrane efflux protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_12050</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="615" mass="68776" checksum="73DC370371FBC7F3" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQ99</accession>
    <name>A0A518IQ99_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Leucine Rich repeats (2 copies)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_12380</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006553">
        <property type="entry name" value="Leu-rich_rpt_Cys-con_subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00367">
        <property type="entry name" value="LRR_CC"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="445" mass="48181" checksum="01CB6C5AF75C9F52" modified="2019-10-16" version="1">MTFVRTIPTLLLTLLLLSGCKKQEVAQPNNEPAEAPAPAAAAEPTPDDAEVVAAIEAAGGVTVKKKGENIVELDLRGLFPDAAEDQADEFAWVAGLPKLQKILARGPGVTLEAVEKLKAHPELKVIGFDNCTQVGDEAVAVLVTLPKLADVDLIKSEITDESLKTLAGCDTIRQIRIARTKVTDAGIKSLEAAKQLELLDLLECSLLTNECATSVGKLTKMRNVRLPNAVDDSGLAQLTDLNNLVALGLQYCRVGPEGIKHLVGLKELKEINLYGASKVDDEVIPLLAQLPKLQKVRARETSIRGENAAAFADMKALRDLDLSESPVQDAVFEHLAKLPNLENLNLWNTEATEEGIAQLKGMTQLKQLNLDNLGDAISDDCLDTIATMTNLELLHLGGTGVTDEGMPKLYGLKKLKRLFITRTYVIEKSTVEALKQELPQAKIEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQH0</accession>
    <name>A0A518IQH0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Arylsulfatase</fullName>
            <ecNumber evidence="7">3.1.6.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">atsA_9</name>
        <name evidence="7" type="ORF">Mal33_13030</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="PTM">
        <text evidence="3">The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the sulfatase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.6.1" evidence="7"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004065">
        <property type="term" value="F:arylsulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024607">
        <property type="entry name" value="Sulfatase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00523">
        <property type="entry name" value="SULFATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022155875" evidence="5">
        <location>
            <begin position="21"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase" evidence="6">
        <location>
            <begin position="24"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="442"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="modified residue" description="3-oxoalanine (Cys)" evidence="3">
        <location>
            <position position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR600917-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV55332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="469" mass="52396" checksum="39B1FA74351B72D5" modified="2019-10-16" version="1" precursor="true">MIRAIVMLVCAWAFIGSTFADRKPNVILIMADDVSWECFGCYGAKDYKTPNIDALAAKGMQFNNCYSTPICTPSRVKLMTGQYNFRNYTHFGYLNPRDKTLAQMLKHAGYKTAIAGKWQLNGLYHRADGCTDAGRVHDAGFDEYCLWQVTKTVYDEGGGERFWSPPLEQNGRMLTKQDNDGLYGPDIMSDYLCDFIQRNRDDPFFVYYPTVLVHNPFVATPDTIGDGDRTHQANKAPKGKAAKKKNFVAMVNYLDKIVGKVVQRVEDIGQLENTLILFTADNGTDRRIASAWNGREVVGGKGTTTDMGTHVPLVAYWKGHTPVGAKRDDLIDFTDFYATFADAAGVVLGADDPVDGRSFLPQLQGRPGNPRDWVVCHYQPYWGKFEGRQFTRNGFFKLYRDGSFYRIPDDLDEANDLAVGDAGIAGESARRFLQQVMQTLPPAPPVQAGKAATTRPVHPDWPNITDPND</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQI4</accession>
    <name>A0A518IQI4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_13150</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="51" mass="5684" checksum="B0E191D08C2C7EFB" modified="2019-10-16" version="1">MNKKNNKASPMTRLIAIVAKQIVLNLSKQIPVDAASEHLAPVQRKKEEDTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQS7</accession>
    <name>A0A518IQS7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DUF1232 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Mal33_13850</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010652">
        <property type="entry name" value="DUF1232"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06803">
        <property type="entry name" value="DUF1232"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="DUF1232" evidence="5">
        <location>
            <begin position="206"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF06803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV55413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1116" mass="123637" checksum="9725CD8D85D26737" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQS8</accession>
    <name>A0A518IQS8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_14180</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="513" mass="55091" checksum="A79655448C5592CB" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQV9</accession>
    <name>A0A518IQV9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Site-specific tyrosine recombinase XerC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_14500</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyr recombinase" evidence="3">
        <location>
            <begin position="164"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV55475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="354" mass="39753" checksum="21E89FFE93C87E33" modified="2019-10-16" version="1">MRKPFFRKQTQAWYVKDDQGRFIRLGKSRKEAFAEWKAMLTTPGSSGSDVLFISLCDDFLVEHEPLLSPLRFADHCRLCQSLVTHLGTGSLAKDVTPGRVTTWLREPKPGKIRKDGTAAEPKVWSTARQKDAVAVVRRVMNWAVQTDRLKKSPVESLETPAAGNREGVIDPNTHRRLVQAAMASDKSRSFACYLIASHCGARPQQIRDITAGHCESDFTHATFTQHKTAKSTGKPLTVYFAPCLQTLLRILAASRPEGRLFRNDHGRPWVKDTVCQRFRRLREQLGLPSDIVPYLYRHTFATDSIRAGQSEAITAALLGHKSSKMVQRIYSHMHRHDNELIEAAAKASAKRLGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQX8</accession>
    <name>A0A518IQX8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acyl carrier protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">acpP_2</name>
        <name evidence="3" type="ORF">Mal33_14670</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="2">
        <location>
            <begin position="4"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="1">
        <location>
            <position position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="86" mass="10080" checksum="65B9FEA04534E490" modified="2019-10-16" version="1">MTPEDIREEIIDILGDIAPDEDLSNLEDAKPFREQLELDSMDFLDIVMELRKRHRVQIPEEEYGQLASMQSTVTYLEPKMKDIVRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IR32</accession>
    <name>A0A518IR32_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">2-keto-3-deoxy-L-rhamnonate aldolase</fullName>
            <ecNumber evidence="2">4.1.2.53</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rhmA_1</name>
        <name evidence="2" type="ORF">Mal33_15280</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="4.1.2.53" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106099">
        <property type="term" value="F:2-keto-3-deoxy-L-rhamnonate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005000">
        <property type="entry name" value="Aldolase/citrate-lyase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03328">
        <property type="entry name" value="HpcH_HpaI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HpcH_HpaI" evidence="1">
        <location>
            <begin position="26"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="254" mass="27846" checksum="D4FCFAE7F369FF09" modified="2019-10-16" version="1">MRNSKTLAKVRAGKPVRMCSFGHFIPAYIQMAADSGYDCLWLDAEHRAFTDREIQTLLSYCHRFDIDCMLRPPTLEKSRLYRYLEDGATGLMIPHVSTADRAAELVQSVKFPPLGDRGQDGVGLDAGFLSRGDEYVEHANRETFLVVQIETPQAVENIDAIAAVPGVDGMFIGPGDLGLRIRRTETNVTIAQANADVAAAAAKHGKFWGGPGLSLENIQELYRAGAQMIAHGNDYDGLLAMIRKSSAELDAIYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IR49</accession>
    <name>A0A518IR49_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_15420</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021820861" evidence="3">
        <location>
            <begin position="21"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="149"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="175"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="69"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV55565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="268" mass="29051" checksum="FC84C8C3877663F2" modified="2019-10-16" version="1" precursor="true">MNRLLKTLLCIVALSQSVWANPSNKSLEQAIEAYNEGFAAVEREQRLRHFRRAELLFAQVAEAGEIENASLYVSLGNAALGAQRIGPAIVAFRRALAIDPSNRQARQNLEHARTLLPDWVPRPEATATSFGSLVGALFGESVARSADQIYLLASIAFLAAAVLLALAIRTDRKGLRNLAGVLAVIWIAFLGTAVWKSYQPTAAVAVVILPDTTARAADSINSPSRLPEPLPSGTEVQVMEDRSDWLRVRLFDGRDAWLPASSVARLAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IR70</accession>
    <name>A0A518IR70_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_15570</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007433">
        <property type="entry name" value="DUF481"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04338">
        <property type="entry name" value="DUF481"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021817381" evidence="2">
        <location>
            <begin position="25"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="402" mass="43887" checksum="86FF902B118AC284" modified="2019-10-16" version="1" precursor="true">MFSPTLIRLILVSSLGLTYGLSSACAQTTIQPLQASGYQPGAYGNSAPTYLPPVDGQSTQYPSIGQSGPAAGSAYSMPTTASVPNPQQVQSSYYQTANDNATYAQNQYLTAPAQNYTPPVPMNDPPSYQGGSVVGSGASQEALPAPEPEPTGDDLGISMMTPLPEQMEQIEEEYSWYHYPWVWIPRDGWDSSVEFGLNGSEGNTNSLSYAAGANLARKSDLYNLGVNLNYRKTSSGGIDTQNNARANFDLDRAIAETDFSAFIKSGLEYDEFKAFDARVNVNSGLSYFLAKTDDVTFITRIGAGASQEIGSVDEDWKPEMLFGLDLKQQVNKRNKIYVKADYFPAFADFSDYRVVTDAGWEILLDDSENFSLKLAATNRYDSTPLGLEPQDIDYTATLLYKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRE3</accession>
    <name>A0A518IRE3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Pectic acid lyase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_16540</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012669">
        <property type="entry name" value="Pectate_lyase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09492">
        <property type="entry name" value="Pec_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="479" mass="53979" checksum="7DA1C5E3E4F77D2B" modified="2019-10-16" version="1">MVCALAAAIAIVAAPIPRSYGDEPPTREQAVAAMHRAVKFFRDQASAGGGYVFRLSEDLSLREGEGKVGDSTAWIEPPATPAVGLAYLNAYRLTNDPILLDAARQTATALINGQLVSGGWGEQIEFAPRDRDRYAYRVDSMEVGKRRNTSTLDDNKTQSSLRFLMQLDSTLEFRDAKLHEAARFGLDRVLTAQYRNGAWPQRFDGPNDQAEVPVVKASFPEQSPKTFPKQKYDSFYTLNDNTHCDAIATMLEAWDTYQDPRYKEAAIRGGDFLLLAQLPQPQPGWAQQYDYQMHPVWARKFEPPSISGGESQGAMQMLLHLYRRTGDKRYLQAVRTALPYFNRSLREDGRLPRFLELQTNRPLYLTRDYAVTYNDNDLPTHYSFVVKARLDSIEKELNRLESLPPDQLWRPGKRKSPKMSDALAKAASQRIDLLDQRGAWVEKGKLKTHAQTPGGRIISSATFIKNLNVLAEYVAAANR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRL2</accession>
    <name>A0A518IRL2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Streptogramin A acetyltransferase</fullName>
            <ecNumber evidence="3">2.3.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">vatD</name>
        <name evidence="3" type="ORF">Mal33_17030</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
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                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
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                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
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                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 4">Mal33</strain>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="217" mass="23571" checksum="D84C90CAEE9E0C56" modified="2019-10-16" version="1">MHGPDPHTQHPLAGFPQVGYLKPILAAAEVENIIVGDYTYYDDPAGPERFIDNVLYHFPFIGDKLTIGKFCAIGRGVKFIMNGANHPMDGVSTYPFWIFGNGWESNAPAAGTLPHKGDTVVENDVWIGYEATIMPGVKIGNGAIIAAKSVVTSDVPAYTIVGGNPAREIRRRFAEPDADRLESIAWWDWPAPEITQHLASIAGADIDELERAITAGE</sequence>
</entry>
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    <name>A0A518IRP2_9BACT</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
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    </protein>
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    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="1 2">Mal33</strain>
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        <source>
            <dbReference type="EMBL" id="QDV55759.1"/>
        </source>
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    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
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        <submittedName>
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    <gene>
        <name evidence="3" type="primary">adrA_1</name>
        <name evidence="3" type="ORF">Mal33_17020</name>
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        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
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    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 4">Mal33</strain>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
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        <property type="entry name" value="Nucleotide_cyclase"/>
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        <property type="entry name" value="PAS-like_dom_sf"/>
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        <property type="entry name" value="PAS_fold"/>
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    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
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        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="515" mass="56584" checksum="C7416B8FF5C6630F" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRX4</accession>
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        <submittedName>
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    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
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                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
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                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="78"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="981" mass="107239" checksum="D5FC3DC0BD1DB47E" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IS62</accession>
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    <protein>
        <submittedName>
            <fullName evidence="5">23S rRNA m(2)G2445 methyltransferase</fullName>
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    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_18720</name>
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    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
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    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019614">
        <property type="entry name" value="SAM-dep_methyl-trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10672">
        <property type="entry name" value="Methyltrans_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltrans_SAM" evidence="4">
        <location>
            <begin position="110"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV55893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="294" mass="32540" checksum="518ABD2EA47040DE" modified="2019-10-16" version="1">MSAESLLQNYQLIDFGDGRKLESIDGYKLDRPSPAAEWDAPAQADAWQQADAVYDGSSWTIFNEWPESLELDAGAFRLAAEPKPFGHVGFFPEQAANWQWLASLADRLPADCRDAMNLFGYTGGSTLALARVGFRVAHIDASKPSVARTGDNARRSELGDAAIRYIVEDARRFAAREIRRGRKHSVIVLDPPAYGHGTKGDSWRIQRDLWPLLEDCLSLLTPRAAMLITGHSDTICDSDISDWLRQNQPAGLEIDEGRCKIPDSSGRSLDAGYFVRATWHLDSPSTMDLSDDAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISG3</accession>
    <name>A0A518ISG3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Polysaccharide biosynthesis/export protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_20000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015159">
        <property type="term" value="F:polysaccharide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003715">
        <property type="entry name" value="Poly_export"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02563">
        <property type="entry name" value="Poly_export"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="447" mass="48243" checksum="A30D92E4E70DF7F5" modified="2019-10-16" version="1">MSCLMNSDGSMTLPNFASVALMCLAGIGGLLHQRADAQQPMQYAQPGYDTSVPHVASANGTVLGAPRAITGPSAAACNCGNLTPPQACLGGCQPCMQGFDCANGQCNPKLKWKNMYPVDFGPYGQGEYAGPSRLSHMREYRVRVGDTLQFTYVLSRDMMRSSYRIGIGDQLLIESLADEEVLTRGTFERGLEVQPDGTISVRILGSIHAAGLTIDQLRDQLEEKYKKYYNEPGIDVTPIKTNILLEDIRNAVGGASGLNEQAISRTVTPDGRVALPKIGPVCVQGLTLGEIKQEVNLRYRSMVVGLEVEAGLQEQATHFVSVLGEVAQPGRFEMQGPTTALSAIALAQGHLVGANLRQVVVFRRAEDWRLISTVLDLRGAILGKSPLPADEIWLRDGDVVVVPSSPIRLFDNFVRQVFTEGIYGIVPFSGFSVVDAVNGFALENVVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISG5</accession>
    <name>A0A518ISG5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Maltose O-acetyltransferase</fullName>
            <ecNumber evidence="5">2.3.1.79</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">maa</name>
        <name evidence="5" type="ORF">Mal33_20140</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the transferase hexapeptide repeat family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.79" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008925">
        <property type="term" value="F:maltose O-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018357">
        <property type="entry name" value="Hexapep_transf_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024688">
        <property type="entry name" value="Mac_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12464">
        <property type="entry name" value="Mac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01266">
        <property type="entry name" value="Mac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00101">
        <property type="entry name" value="HEXAPEP_TRANSFERASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Mac" evidence="4">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV56035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="183" mass="19826" checksum="CE6188B64E1760A0" modified="2019-10-16" version="1">MLAGALYDALDPELVADRERARDLCHDLNASRERDQELRRRLLTELLGSGGDSVWIQPPFYCDYGSNIRLGQRVYFNFNCVVLDVCAVDIGDFSFFGPGVQIYTASHPLEAKLRRTQEFGKPVSIGSDVWVGGGAIILPGVTIGSRTVIGAGSVVTKDIPEGVLAAGNPCRVIRENIAGDSDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISJ8</accession>
    <name>A0A518ISJ8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">N, N'-diacetylbacillosaminyl-diphospho-undecaprenol alpha-1,3-N-acetylgalactosaminyltransferase</fullName>
            <ecNumber evidence="2">2.4.1.290</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">pglA_1</name>
        <name evidence="2" type="ORF">Mal33_20550</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.4.1.290" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102335">
        <property type="term" value="F:N,N'-diacetylbacillosaminyl-diphospho-undecaprenol alpha-1,3-N-acetylgalactosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="1">
        <location>
            <begin position="12"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="370" mass="40220" checksum="470836278F192257" modified="2019-10-16" version="1">MRIDLVITELFVGGAERQLTQLAIGLARRGAAVRVIALDVLPDTSPDDALVRQLRDAGIDVRSLGCRSIWAVPQAIARLRRLFLDDRPDLVQTFLFHANVVGTWAASRVGIPICVGGVRVAQPNSARLWLERQAARRMQAIVCVSQAVEKFAAQHLATSATTLLTIPNGVDTQRFAQAKPIGWETLGLDRAAEVILYVGRLHPQKGTDWLLEAAPRILAENRRAALVLVGSGPWQPRVEEALAKLPAGRAVHLPLQADIAPLMLAARLLVLPSRYEGMPNVVMEAMAAGMPVLATDAEGVRELLGEWGEPQIVSFGDTDSLCGQLSHLLNDASLAAQVSNSNRLRASEEFSVDAMVDRYWELYSRLSGTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISK6</accession>
    <name>A0A518ISK6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosomal RNA small subunit methyltransferase H</fullName>
            <ecNumber evidence="6">2.1.1.199</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">16S rRNA m(4)C1402 methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">rRNA (cytosine-N(4)-)-methyltransferase RsmH</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 7" type="primary">rsmH</name>
        <name evidence="7" type="ORF">Mal33_20570</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>cytidine(1402) in 16S rRNA + S-adenosyl-L-methionine = H(+) + N(4)-methylcytidine(1402) in 16S rRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42928"/>
            <dbReference type="Rhea" id="RHEA-COMP:10286"/>
            <dbReference type="Rhea" id="RHEA-COMP:10287"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74506"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="EC" id="2.1.1.199"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the methyltransferase superfamily. RsmH family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.199" evidence="6"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071424">
        <property type="term" value="F:rRNA (cytosine-N4-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01007">
        <property type="entry name" value="16SrRNA_methyltr_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002903">
        <property type="entry name" value="RsmH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023397">
        <property type="entry name" value="SAM-dep_MeTrfase_MraW_recog"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11265">
        <property type="entry name" value="PTHR11265"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01795">
        <property type="entry name" value="Methyltransf_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004486">
        <property type="entry name" value="MraW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81799">
        <property type="entry name" value="SSF81799"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00006">
        <property type="entry name" value="TIGR00006"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="5 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 6 7" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="6">
        <location>
            <begin position="39"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="59"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV56078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="307" mass="34208" checksum="6562119323082544" modified="2019-10-16" version="1">MPDSDSSTSMHVPVLPSEVIEALDLSPGKRIVDGTFGGGGHSRLILPAIAPGGMLIGLDRDPRAIQQYGPQWRDSLPAIESDPPPRIELINDSYHRLPQLIEELEIDGVDGILLDLGLSSDQLNDPSRGFSYQTDGDLDLRFDPTCGEAASDLLLRLPEKEIADLIYQFGEERCSRRIARRIVERRKERRAVKTADELASLVRSCVPRGKNHRIDPATRTFQALRIAVNQELRIVKQSLEDLPGCLRPGGRLAVISFHSLEDRLVKHAFREADDLEIITRKPILASDRENAENPRARSAKLRVAVKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISX4</accession>
    <name>A0A518ISX4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alkaline phosphatase D</fullName>
            <ecNumber evidence="3">3.1.3.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">phoD_1</name>
        <name evidence="3" type="ORF">Mal33_21610</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.3.1" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004035">
        <property type="term" value="F:alkaline phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07389">
        <property type="entry name" value="MPP_PhoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018946">
        <property type="entry name" value="PhoD-like_MPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038607">
        <property type="entry name" value="PhoD-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09423">
        <property type="entry name" value="PhoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022101432" evidence="1">
        <location>
            <begin position="26"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="domain" description="PhoD" evidence="2">
        <location>
            <begin position="193"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="502" mass="56070" checksum="97AD99BBEC8726F2" modified="2019-10-16" version="1" precursor="true">MLSLTTPNRLSFPFLVLLASAVAVSAQPPNPKAVPKAGMGIMVGELTSASANVQVRLTSTDTLVDRDLPGLAGTVAFQLFKEGSAQVVGKQILKASQQRDFIARASFRSLDPATRYRCETELTSSAGITQPGPVARFKTLPATEAAAEVRFVVVTGMNYAKFHGDQRIDLKQHKVQNNTNLPAPYEGVDKHLGYPALASILKLQPDFFVGTGDNVYYDTPNKPRAKSVEELRQKWHEQFVQPRFRDLFAAVPTYWMIDDHDYRRDDCDNSGNYSPSPVLGRRLMLEQLPVAQADDADAKTYRTFRIGKDLQIWMTENRMYRSDNKMEDGPDKTIWGAEQKAWLMKTLEASDATFKLLISPTPMVGPDDKRKTDNHANIGGFRTERDQFFAWLKTKQLDQGNFFVVCGDRHWQYHAIDPSGFEEFSCGALVDANSRLGRKAGDPASTDPEGLIKQPYLQDPRSGGFLEIHLTPAADDSQPATLHFRWRDEQGVLLHETSKSAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISY6</accession>
    <name>A0A518ISY6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_21790</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="75" mass="8093" checksum="A71A767D516157F5" modified="2019-10-16" version="1">MTDLGKINISLAFPLSGSRQLAGLPRCSPIAIAAELQSVGHGKSYLSAAPQTRRGWLELQPLNVLQLNLRSLVRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IT47</accession>
    <name>A0A518IT47_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_22320</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="323" mass="36258" checksum="63B4BB92000A0551" modified="2019-10-16" version="1">MVRYRTQSISITCRVSQQLSSEFMQIRSATLEKLASFICGDDPLPFPYRSSSKLTAFFTGLDLDYIHRGETRNTWTRESLIDVNRKPGPVGGYASSQAAMYAVIEEIMNPSFYEQVDDGAFEQCLELMNKTLRPYQLEVVFDDQAWTTSLVSMDGKFVSTAHRSPEKATKITFSPRVFEVPDGVEPRKNLVAIMMPFGGFDGVHKAIKSACEKAGLDSKRADDIWDNSTILQDIFDLIYSAEIVVSDFTNRNPNVMYETGVAHTLGKHVIPITQTLEHIPSNLHGHRSLLYVGANSQGLQQLESDIYERLVTITKGRKLGSPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IT66</accession>
    <name>A0A518IT66_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Site-specific DNA-methyltransferase (adenine-specific)</fullName>
            <ecNumber evidence="3">2.1.1.72</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">dpnM</name>
        <name evidence="8" type="ORF">Mal33_22670</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2'-deoxyadenosine in DNA + S-adenosyl-L-methionine = an N(6)-methyl-2'-deoxyadenosine in DNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:15197"/>
            <dbReference type="Rhea" id="RHEA-COMP:12418"/>
            <dbReference type="Rhea" id="RHEA-COMP:12419"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90615"/>
            <dbReference type="ChEBI" id="CHEBI:90616"/>
            <dbReference type="EC" id="2.1.1.72"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the N(4)/N(6)-methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.72" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="REBASE" id="356407">
        <property type="entry name" value="M.PbaMal33ORF22670P"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009007">
        <property type="term" value="F:site-specific DNA-methyltransferase (adenine-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1020.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023095">
        <property type="entry name" value="Ade_MeTrfase_dom_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012327">
        <property type="entry name" value="MeTrfase_D12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30481">
        <property type="entry name" value="PTHR30481"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02086">
        <property type="entry name" value="MethyltransfD12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00505">
        <property type="entry name" value="D12N6MTFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="7">
        <location>
            <begin position="58"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV56285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="359" mass="42287" checksum="D4C6C7E899BD83DD" modified="2019-10-16" version="1">MNSQPPQAIKFQHNVRFLLRSRWLSQKEGSDQIGVPYKWLRRLCHQGIERIDKRSRGNLEKLAQFFGVDVDELWSDRIQNVPRSNWVLIKWIGSKRRLAPEILRRFPRQIKTYWEPFLGSGAMLKELLASDIEVERIRCSDACEPLIGIWNLIKDNPRQLSEAYRRLWSELQSGEQRVYNEVRDRFNDIADPCDFFFLLRTCRVGAVEFSQQGKFITPYHLGELGLEPKFVDVLLADWHRKLKGRDVVFTVRDYRSVFSRHGDFMYLDPPYRSDRERLYYGPFDHDEFFGWLKKQRAGWALSLNGPAEIGDFVPEIYDERFELPNGTSAVRRLSGRQTPSITESLFVRAAVDPRPNENE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IT69</accession>
    <name>A0A518IT69_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nuclease-related domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_22680</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011528">
        <property type="entry name" value="NERD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08378">
        <property type="entry name" value="NERD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50965">
        <property type="entry name" value="NERD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NERD" evidence="1">
        <location>
            <begin position="18"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="344" mass="38421" checksum="C31C8395DF2FD14C" modified="2019-10-16" version="1">MIVKEKEGSIPTDKMGRAGYDAEKQMAFYLRRAFSESPDIFVFNDIRFVRNGEAAQIDHLVLHRYGFFLIESKSVTGAIEVNKQLEFVRVFGRQRKGMKSPITQVKMQADLLQALLNDNKESLRRKVMLGMVQGSFGEQRFDRLVAVSDNGIINRKGCDPPGLVKADRVASVVEDLIARRDKTRGFTGAMRLAFADKKTTKQLQEDDMPAFTAGELDLICSFLLDNDQPYVQPPPVVGQVVSPPETPPPPPAAANVQSVAAEIVRESPAQTQTSFSCRHCNATNVEIVYGQYGYYFKCNDCSKNTKIDFTCRCGVKSKISKKGQIFSWKCSSCGNNDHFYTNPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IT82</accession>
    <name>A0A518IT82_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Mal33_22550</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032808">
        <property type="entry name" value="DoxX"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13564">
        <property type="entry name" value="DoxX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="44"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="68"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="98"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV56273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="125" mass="14220" checksum="F812E39994763CD9" modified="2019-10-16" version="1">MKRIKSISKYLLAIFMIVAGTMHFVNPEFFLKIMPPYLPLHKELVLVSGVCEILLGVLLLIPKCSHLAAWGIIALLIAVFPANVYLYQHPEILPASPIIHLLRLPLQGVFILWAYWHTRPAERKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITL1</accession>
    <name>A0A518ITL1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acetolactate synthase, catabolic</fullName>
            <ecNumber evidence="4">2.2.1.6</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">budB</name>
        <name evidence="4" type="ORF">Mal33_24130</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TPP enzyme family.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.6" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003984">
        <property type="term" value="F:acetolactate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012000">
        <property type="entry name" value="Thiamin_PyroP_enz_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000399">
        <property type="entry name" value="TPP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045229">
        <property type="entry name" value="TPP_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011766">
        <property type="entry name" value="TPP_enzyme-bd_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18968">
        <property type="entry name" value="PTHR18968"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02775">
        <property type="entry name" value="TPP_enzyme_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00205">
        <property type="entry name" value="TPP_enzyme_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00187">
        <property type="entry name" value="TPP_ENZYMES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TPP_enzyme_M" evidence="2">
        <location>
            <begin position="34"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="TPP_enzyme_C" evidence="3">
        <location>
            <begin position="226"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV56423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="394" mass="43596" checksum="4455ED0EA517B942" modified="2019-10-16" version="1">MHLELPEDIAAEQVDEQPIPASLVRRPVAEDKSIHAAVEMIRAAESPLLLVGAGANRKRTCNMLRKWVAKLGIPFATTQMGKGVIDERDPWFLGNTALSSNDFVHRAFEAADLIINVGHDVVEKPPFFMHAGGVKVIHVNFSSASVDPVYFPQVEVVGDIANSIWRLMEQLEPQPHWDFSRFMTVRTAGETSVAQGADDDRFPVYPQRLVADVRQAIQKRGIIALDNGIYKIWFARNYKATAPNTVLLDNALATMGAGLPSAMAAKLVHPDRQVMAICGDGGFMMNSQELETAVRLKLDLVVLVLRDDAYGMIKWKQTNMGLKNFGLDYGNPDFVKYAEAYGANGHRVASSEALLPLLSRCLNSPGVHLVEVPIDYSENDRILNHEIRELSSKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITS8</accession>
    <name>A0A518ITS8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_24830</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008660735.1">
        <property type="nucleotide sequence ID" value="NZ_CP036318.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007352">
        <property type="entry name" value="DUF420"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04238">
        <property type="entry name" value="DUF420"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="148" mass="15998" checksum="A1201968FC18C187" modified="2019-10-16" version="1">MNTATLILTAVLILNLFAPFAVYYAIGLAKEGLYKTHKRIQNAVFIACVLGVLTLEGLIRFSGGSGSLAENSSFSGTTIFKTILAAHIIGAILTYILWTFQIVVSNRKFGEKLLGSFASMHKTIGYILFLGLIYTAVTAAIVCAMVWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITZ9</accession>
    <name>A0A518ITZ9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Retaining alpha-galactosidase</fullName>
            <ecNumber evidence="5">3.2.1.22</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_25550</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.2.1.22" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052692">
        <property type="term" value="F:raffinose alpha-galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008152">
        <property type="term" value="P:metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029483">
        <property type="entry name" value="GH97_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019563">
        <property type="entry name" value="GH97_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029486">
        <property type="entry name" value="GH97_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14509">
        <property type="entry name" value="GH97_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14508">
        <property type="entry name" value="GH97_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10566">
        <property type="entry name" value="Glyco_hydro_97"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021859723" evidence="1">
        <location>
            <begin position="22"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="domain" description="GH97_N" evidence="3">
        <location>
            <begin position="35"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_97" evidence="2">
        <location>
            <begin position="295"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="domain" description="GH97_C" evidence="4">
        <location>
            <begin position="536"/>
            <end position="631"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF14509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV56563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="635" mass="71402" checksum="CD6EE16F4AB5DC5D" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IU78</accession>
    <name>A0A518IU78_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_26250</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="122" mass="13485" checksum="021C789A7390845D" modified="2019-10-16" version="1">MHALTIEAAVMYDRQAAIALAAGSWIGWNKRASSRTNRGRTPPVANSHLEAESEFLRLLRSGHPFAFEDAAKLIRTPEGFDGRALGAIPARMHRDGEIVKAGYRTSESAKHHAVIKQLWRLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUH8</accession>
    <name>A0A518IUH8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Acetyl-CoA acetyltransferase</fullName>
            <ecNumber evidence="7">2.3.1.9</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">thlA_1</name>
        <name evidence="7" type="ORF">Mal33_27360</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the thiolase-like superfamily. Thiolase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.9" evidence="7"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003985">
        <property type="term" value="F:acetyl-CoA C-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00751">
        <property type="entry name" value="thiolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002155">
        <property type="entry name" value="Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020615">
        <property type="entry name" value="Thiolase_acyl_enz_int_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020610">
        <property type="entry name" value="Thiolase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020617">
        <property type="entry name" value="Thiolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020613">
        <property type="entry name" value="Thiolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02803">
        <property type="entry name" value="Thiolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000429">
        <property type="entry name" value="Ac-CoA_Ac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01930">
        <property type="entry name" value="AcCoA-C-Actrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00098">
        <property type="entry name" value="THIOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00737">
        <property type="entry name" value="THIOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00099">
        <property type="entry name" value="THIOLASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thiolase_N" evidence="5">
        <location>
            <begin position="8"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="domain" description="Thiolase_C" evidence="6">
        <location>
            <begin position="265"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="3">
        <location>
            <position position="90"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="338"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000429-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV56738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="379" mass="39166" checksum="655A0EC7F09C15E6" modified="2019-10-16" version="1">MEKSGKTVWIVAAKRTPQGRLLGALAKQSAVDLAVAAGREVVASVDPGWIDSVIVGNVLSAGLGMNVARQVGVRLGLPVSTPAFTVNMMCGSGMQAVILAAQAIQNGSAKMVLCGGTESMSNAPHLMQRARRGYKLGDAVLVDSVLRDGLTDAFSGDHMGQTAERLAAKYGISRAAQDAFAVRSQTLCAAAQQAGRFADEIVAVDGCVEDEHPRPGTTVEQLAKMSPAFQSDGTVTAGNASGINDGAAMLLLCDEDWGRQCGLEPMMVLTASAVAGCEPELMGLGPVHAVRKLGVDPQSFDAIELNEAFAAQSLACMRELKLDEALVNCDGGAIALGHPIGASGARLIVHLAHRRPRRGLATLCVGGGMGCAVVLDKPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUK4</accession>
    <name>A0A518IUK4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_27730</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="76" mass="8248" checksum="71EE5B0E86C8B1EA" modified="2019-10-16" version="1">MRPPLPRLRRWFERGGHAPQACTSLAGLASFGLGYAKDRSFAPQAKVQAAGAAIAYSLRREPQDHFPTGPMRGQVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUL6</accession>
    <name>A0A518IUL6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_27810</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018841">
        <property type="entry name" value="DUF2442"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10387">
        <property type="entry name" value="DUF2442"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="94" mass="10352" checksum="2A8E6C091ADDB82E" modified="2019-10-16" version="1">MAGSEIKPGERVKDVHFGDDAFSVDLLDGRTITVPYAWYPRLLHASPEHRANWRPCGGGFGIHWPDLDEDLSTEGLLRGAPAPRETEQASGRPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUQ7</accession>
    <name>A0A518IUQ7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_28240</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="64" mass="6607" checksum="0C6382B2F4BE4B59" modified="2019-10-16" version="1">MVAGGRRAAAHLRNATPPTRDDPRGITDRSDQAGGDSGSIDARVSDDVAAIKAAATTWGLYGIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUV5</accession>
    <name>A0A518IUV5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_28770</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="466" mass="50244" checksum="0DADD16988164B7B" modified="2019-10-16" version="1">MLGVAILAILSINWGFAQDSLLRTNPSFGGSAGVPSTNLVPVPSTSANALQSPPYPQTVAPTLPPNTQPIAPPAASLGPPQFDPYQAQPNNNPMSGFFGGAYNPAPTAGPIGYPTTPTPYGAQPASPYGAAPAPSPYPSPYPTQGASAPLGQAGGAYPSSVYPGTAPPVLFPGGLNWNVPAPNMQGWNPSGSMFDAGQGSFQFLQGPRFRQAWVSGNNSPESLDILDSDFSLALNWPNFLGSFQPLYILPSFSLHQWQGPNSSTGADLPSKAYSAFIDVGWQSDPNLMFGTELGLRTGVFTDFETFNDKSFRIMGQALAKLRITPATTLKLGVYYIDRNEVKIIPAGGFLWQPTPHSRWDIFFPLPKLSHYLTTVGTQDIWWYLSAEYGGGSWTVTRADGAEDSIDINDIRVMIGLEWGRSDLIKSGRRIGFFEAGFVFDRELDYRYSPDDIDNNDTFVLRAGFGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUZ6</accession>
    <name>A0A518IUZ6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glycine dehydrogenase (decarboxylating)</fullName>
            <ecNumber evidence="7">1.4.4.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Glycine cleavage system P-protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Glycine decarboxylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Glycine dehydrogenase (aminomethyl-transferring)</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">gcvP</name>
        <name evidence="9" type="ORF">Mal33_29100</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 7">The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>(R)-N(6)-lipoyl-L-lysyl-[glycine-cleavage complex H protein] + glycine + H(+) = (R)-N(6)-(S(8)-aminomethyldihydrolipoyl)-L-lysyl-[glycine-cleavage complex H protein] + CO2</text>
            <dbReference type="Rhea" id="RHEA:24304"/>
            <dbReference type="Rhea" id="RHEA-COMP:10494"/>
            <dbReference type="Rhea" id="RHEA-COMP:10495"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83143"/>
            <dbReference type="EC" id="1.4.4.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7 8">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4 7">The glycine cleavage system is composed of four proteins: P, T, L and H.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the GcvP family.</text>
    </comment>
    <dbReference type="EC" id="1.4.4.2" evidence="7"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004375">
        <property type="term" value="F:glycine dehydrogenase (decarboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019464">
        <property type="term" value="P:glycine decarboxylation via glycine cleavage system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00613">
        <property type="entry name" value="GDC-P"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00711">
        <property type="entry name" value="GcvP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003437">
        <property type="entry name" value="GcvP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020581">
        <property type="entry name" value="GDC_P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11773">
        <property type="entry name" value="PTHR11773"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02347">
        <property type="entry name" value="GDC-P"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00461">
        <property type="entry name" value="gcvP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7 8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="7 8">
        <location>
            <position position="728"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00033655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR603437-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV56909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="981" mass="106867" checksum="1E229EF10288F350" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IV05</accession>
    <name>A0A518IV05_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_29290</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011521">
        <property type="entry name" value="YTV"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07639">
        <property type="entry name" value="YTV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022239033" evidence="2">
        <location>
            <begin position="22"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="392"/>
            <end position="482"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="482" mass="54947" checksum="29B567BE3F6B91B8" modified="2019-10-16" version="1" precursor="true">MTHKKNIIALVSLCTAVSVPAAVEAQDECCFRPAYRMQCETVYEEQKVTNYRLVYETNYVEREITEEKPVVETKMEQRTYRVAKPIVETTYREDRYTVMKPVLETSYREEMRAQTRYVTETAEREEQVTTYRPVTTTQYQQQQQVVQRPVVETQYQTENVTTFRPVTTVQQQVVDQGGYVAQQYVQPGTVGYAAQWNPAAYYQPGPFGVFATRRGAYQAVPYATPATVQTQMTYRPNYVTQQYQQTTMVPQVVQQQRPIQVTRMQSEVVTQNIPVQVTTMQPTTEVRKIPYQVSRPVTEYIKHQVPVQSYKMVPEEHVRRVPVQTQRITYETRVEQVPVKVYKTQTVVKKVRVPQTTARYVPYTTTRLVPRQVMQRVPLTYYDPYSAAIVSSSPVETSMSITPTPAEATEEKPGVTSHKVETELEAVEEVEEVDSPEPTADPATDAPAKDSTIDSPSDKDPIDAPTLNGPGNGANDRPSTEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVB7</accession>
    <name>A0A518IVB7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">prkC_9</name>
        <name evidence="9" type="ORF">Mal33_30340</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="101"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="6">
        <location>
            <begin position="790"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV57033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="885" mass="96461" checksum="D0FCFE7301B8031E" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVG1</accession>
    <name>A0A518IVG1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">TadE-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_30740</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012495">
        <property type="entry name" value="TadE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07811">
        <property type="entry name" value="TadE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="142" mass="15194" checksum="A0AD5B549F564C3A" modified="2019-10-16" version="1">MMVKQIVKLPFGNRSRKGVAAVEMAIVAPTILLIAFGVQEVTAAIHLQQTLTICAYEAARVALQPDTTEANVKATCDKILLARRVVNASVKVTPSDYQNKDYGTEITVTVSADLEGNSLGPLLVLSNRSVVGEVTVMKEHGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVH9</accession>
    <name>A0A518IVH9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_30890</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="109" mass="12372" checksum="21A116DFC372EED4" modified="2019-10-16" version="1">MRRRKRARQTRRSALNTLPMTGFAVRWRGRRKAKCIGEQPVLPREEFAAARVWRIGRLGGAVDYASRLFAFNRDRVRLIARTMPLALLTVSSYSASGLLSATTPQPAWT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVJ8</accession>
    <name>A0A518IVJ8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Flp/Fap pilin component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_31080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007047">
        <property type="entry name" value="Flp_Fap"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04964">
        <property type="entry name" value="Flp_Fap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="56" mass="6181" checksum="56DD0DA5C50DA877" modified="2019-10-16" version="1">MKKFTEKVVDFLKEEDGPTAVEYAVMMALIIVVCLSTVKTIGTKANSQFTKIADNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVL9</accession>
    <name>A0A518IVL9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_31260</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010297">
        <property type="entry name" value="DUF900_hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05990">
        <property type="entry name" value="DUF900"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="410" mass="44744" checksum="BEC01FF23BE64CD7" modified="2019-10-16" version="1">MTASPFGLLIGLLLSLILVPAQLLAQQSAPPSQVQAAPPAAPSAIATPSETPAADGAAPSEAAIGDSLLAEPTESVAEDVVGKEAVAAELETAPLAEFDVRSLDQVWTISSRCVGSHHAPVQSLQFRRRIEGNRWQTESAESFFADNAGPLPMRTILFVHGNRTPEVKALRRGLQTYDQTVLNWQRPDSAVRFVIWMWPADKISGQLRDVRVKAARADLHAFHLARVITEIQPQQQVSVIGYSFGGRLAVGAMHLLGGGSLCGSRLPMTDPELPWINLALLAPAIRNDCFVTSRNAALRPVDHLFVLHNSRDQYLKLYRFLKLDNHTPALGYTGLCGLGRHQLASDRVHQYDAARSVGSDHNYLEYVADRRIESLVRQNIFFDTGAVPPHAVGHPHVGGQPEIRSFRLSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVX2</accession>
    <name>A0A518IVX2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_32380</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="547" mass="59198" checksum="E98907246297FD46" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IW80</accession>
    <name>A0A518IW80_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_33550</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011453">
        <property type="entry name" value="DUF1559"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07596">
        <property type="entry name" value="SBP_bac_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="335" mass="35899" checksum="4D44B56743EF1052" modified="2019-10-16" version="1">MKPKSLRSGFTLVELLVVIAIIGILVGLLLPAVQAAREAARRMSCSNNMKQIGLALHNYHDVHRTFPVGAFYNKHGSNWRALILPFIEETAAHDQINFETGGFWAHDVATQSNNPIFSSLRIAGYVCPSSPHGVTNIGDIPLSQHASTGNTSMVMDYVGVSGATPDLNGRTSACTADNIVSGGTYCNNGMMTVYFNKRFRDCTDGTSNTLIIGEQSGNVNGKEASANPLGGWHGWVNNSGEQMLENMSLSSFSSLAAYAGGITTVRYSPNAFWKSGAPSSASSQYEVNTILNSFHPGGIHGLLTDGAVRFVSETVELDTMIKLSIRDDGQVLGEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWN4</accession>
    <name>A0A518IWN4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative diguanylate cyclase YdaM</fullName>
            <ecNumber evidence="4">2.7.7.65</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ydaM_2</name>
        <name evidence="4" type="ORF">Mal33_34960</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.65" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052621">
        <property type="term" value="F:diguanylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="1"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="3">
        <location>
            <begin position="150"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV57486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="300" mass="33016" checksum="64CFFA7261DA8526" modified="2019-10-16" version="1">MLLHRMLQHAPTNGFEVCVCKTAEAAIDRLGDHQYDGLIINLDHEDQDPFEVLLRIRNLDPRLAILGITDRSDESFGLRMVECGAQDVIAKEMLNGQLLYRAMRYGIARQRQISCLKTAAHTDALTGLGNRRALDQALDQAVADFAVDRQPFGFLILDVDNFKQFNDQHGHRAGDYVLSQLGSLLRTAVTGNDLCSRYGGEEFAILIPATSTAKAVAKMKDLLQRIAEHFVEFEGTQYRVTSSAGLTISRPNDTVGSIIERADIALYRAKSDGRNRGDLNLPSSAAVPLSCETIAGGNQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWP7</accession>
    <name>A0A518IWP7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_35320</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="111" mass="12902" checksum="31F1A00BF851D448" modified="2019-10-16" version="1">MNMDRWSQKNDWLNQYNEMLVEETHGLVQQLWLDAEGDSAVVHGRAASYYAVQLAIRATQTFGHRHPVFDETRLSLTVAQRQLKLTIPHRRRKGRASTQADTRQRELTLVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWQ2</accession>
    <name>A0A518IWQ2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative hydrolase YxeP</fullName>
            <ecNumber evidence="2">3.-.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">yxeP_3</name>
        <name evidence="2" type="ORF">Mal33_35290</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.-.-.-" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017439">
        <property type="entry name" value="Amidohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11014">
        <property type="entry name" value="PTHR11014"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005962">
        <property type="entry name" value="Pept_M20D_amidohydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01891">
        <property type="entry name" value="amidohydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="M20_dimer" evidence="1">
        <location>
            <begin position="205"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="412" mass="44679" checksum="88F8BDF4524E84CF" modified="2019-10-16" version="1">MESQASHEPVAWRGPLDVAVEESLEGLFQLRRYLHQHPELSGEEFETTTHVARLVEGLGLPLKVADQQRGLTCELIAPESASDLPRLALRADIDALPIQDAKQVDYHSSCEGVMHACGHDVHTTMLYGALRVLKQLAAGDHLPWPIAVRGIFQPAEETAVGARYMISNHALRDVAAIIGIHCDPSRSVGRIGISPGVLTANCDMFKAKFRGRGGHGARPHQTIDPIDAATQWVQSVYRTVSRAFDPHEATVISIGRFEAGNKANVIPDNAILEGTLRTFHSGARASALETIGKISEAVTLATGCDIDFELGFSAPAVDNDPALVEVISHAARQTLGKHAVEPIPRPSMGSEDFSYYLEHLPGAMFRLGTCSEQIGQEPLHSPHFDIDQRAIAGGVRLLAATVIEYFDPRRNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWR5</accession>
    <name>A0A518IWR5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aldehyde-alcohol dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">adhE</name>
        <name evidence="3" type="ORF">Mal33_35160</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017000">
        <property type="term" value="P:antibiotic biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08182">
        <property type="entry name" value="HEPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001670">
        <property type="entry name" value="ADH_Fe/GldA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018211">
        <property type="entry name" value="ADH_Fe_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039697">
        <property type="entry name" value="Alcohol_dehydrogenase_Fe"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035873">
        <property type="entry name" value="PhpC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11496">
        <property type="entry name" value="PTHR11496"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00465">
        <property type="entry name" value="Fe-ADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00913">
        <property type="entry name" value="ADH_IRON_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe-ADH" evidence="2">
        <location>
            <begin position="8"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="386" mass="40829" checksum="15529A56C1D310B3" modified="2019-10-16" version="1">MTDQNDSVFLEPGDLAKVAQIVQDLAAKRIMMVVDRAAYDASGAAAVIQPILEALEVSWFCEFELNPKLADVQRGVDQARAFDPELVIALGGGTAIDLGKLISSLSHQEASPREIVTGQASIERAGTPLLAIPTTSGTGSEATHFAVAYVGHDKYSIADDSLLPRYTIVDAQLTYSLPATITAATGLDAFCQAIESIWAVGSTDESIGYAVAAGRFALQHLVAATHRPTPADRLGMCRAAHLAGRAINISKTTASHALSYPLTSLHEIPHGIAVAMTLSPMLAYNAQVSDSDCTDPRGAEAVRRRIAIIVELLEAADVADACQRIEAFFAELGCPASLAEAGICDEQALRQIVDSVNTQRLSNNPRSASPETLLQLLKGNLAENEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXP9</accession>
    <name>A0A518IXP9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_38610</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="103" mass="11628" checksum="730C8B11AEFC19D9" modified="2019-10-16" version="1">MNDKFVAREWNDLCHRVIRTASRLGRRFDRSDHFGQEAHDFCALAPPESYPELLVRVREAAELAKAWQAPLPSCGRLSENSIDEALDESFPASDPPAWTASMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXX4</accession>
    <name>A0A518IXX4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">ATP synthase subunit alpha</fullName>
            <ecNumber evidence="9">7.1.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">ATP synthase F1 sector subunit alpha</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">F-ATPase subunit alpha</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9 13" type="primary">atpA</name>
        <name evidence="13" type="ORF">Mal33_39560</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:57720"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.1.2.2"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the ATPase alpha/beta chains family.</text>
    </comment>
    <dbReference type="EC" id="7.1.2.2" evidence="9"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045261">
        <property type="term" value="C:proton-transporting ATP synthase complex, catalytic core F(1)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd18113">
        <property type="entry name" value="ATP-synt_F1_alpha_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01132">
        <property type="entry name" value="F1_ATPase_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.150.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01346">
        <property type="entry name" value="ATP_synth_alpha_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023366">
        <property type="entry name" value="ATP_synth_asu-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000793">
        <property type="entry name" value="ATP_synth_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038376">
        <property type="entry name" value="ATP_synth_asu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033732">
        <property type="entry name" value="ATP_synth_F1_a"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005294">
        <property type="entry name" value="ATP_synth_F1_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004100">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036121">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00306">
        <property type="entry name" value="ATP-synt_ab_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02874">
        <property type="entry name" value="ATP-synt_ab_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039088">
        <property type="entry name" value="F_ATPase_subunit_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50615">
        <property type="entry name" value="SSF50615"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00962">
        <property type="entry name" value="atpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="4 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9" id="KW-0139">CF(1)</keyword>
    <keyword evidence="9" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="5 9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ATP-synt_ab_N" evidence="12">
        <location>
            <begin position="25"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-synt_ab" evidence="10">
        <location>
            <begin position="149"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-synt_ab_C" evidence="11">
        <location>
            <begin position="371"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="169"/>
            <end position="176"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Required for activity" evidence="9">
        <location>
            <position position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="QDV57940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="504" mass="54053" checksum="4CAFA1CB6D83EC46" modified="2019-10-16" version="1">MKFNSDEIASVLQQEIEQYESKVDVREVGTVLEVGDGIARVYGLSGVMAGEMVEFPNGSIGLAFNLEESSVGVIILGDYLTIEEGDEVKALGKLLSVPAGDAVAGRVLDPLGNPMDGKGPVQSDIRRDVEVIATGVSERQPVHEPLQTGIKAIDAMTPIGRGQRELIIGDRKTGKTAVAIDAIINQKGTGVKCFYVAIGQKDSAVATVVDALEKHGAMDYTTIIVAGASAPAPLQYVAPYAGTAMAEHFMFNGQHALIVYDDLSKQAVAYRQMSLLMRRPPGREAFPGDVFYCHSRLLERSSKLNDELGGGSLTSLPIIETLEGEVSAYIPTNVISITDGQIYLQPDLFFAGVRPAMNAGISVSRVGGAAQIKAMKKVAGGLRLQLAAFRALEAFAQLGTDLDAATQQELDRGYRMVELLKQPQYSPLDVSLQVISLYAGTKGFLDDVAVDKVQEFEKALLQFINDKHSGIASSIKELGEMSDDVTEKLEAAIKDFKQGWKPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXY4</accession>
    <name>A0A518IXY4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_39660</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="525" mass="58895" checksum="875E3A10FCA1AB91" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXY7</accession>
    <name>A0A518IXY7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ</fullName>
            <ecNumber evidence="1">4.2.1.59</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">fabZ_2</name>
        <name evidence="1" type="ORF">Mal33_39640</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="4.2.1.59" evidence="1"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008659">
        <property type="term" value="F:(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008693">
        <property type="term" value="F:3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047451">
        <property type="term" value="F:3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004317">
        <property type="term" value="F:3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013114">
        <property type="entry name" value="FabA_FabZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30272">
        <property type="entry name" value="PTHR30272"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07977">
        <property type="entry name" value="FabA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="144" mass="15893" checksum="D71A06E9D4CFD7AC" modified="2019-10-16" version="1">MTAEKIEAAIPHRLPMRLLDEIVEQTEQTIVCKKSFHSDEFFVQGHFPGYPIVPGVIQCECCLQAGAILLSKQTPQDGSVVPVATRMDNVKFKKMVRPGDTVEIHVTLNEQLSNAFYMTGKVMLDGKLAARLDFACSVATPEEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IY61</accession>
    <name>A0A518IY61_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_40370</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="90" mass="9994" checksum="E0056F1AEB77F6B0" modified="2019-10-16" version="1">MEQFYFHENCKVCGRPMIVSLELLNAAIRCGHCGAICDAPRLDQPKWHPQRRTTPGVAAGTSNRPEQVGRVAALLRTIAPPRPCDTPLMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IY75</accession>
    <name>A0A518IY75_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Phage-related baseplate assembly protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_40480</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the VgrG protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006531">
        <property type="entry name" value="Gp5/Vgr_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017847">
        <property type="entry name" value="T6SS_RhsGE_Vgr_subset"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006533">
        <property type="entry name" value="T6SS_Vgr_RhsGE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037026">
        <property type="entry name" value="Vgr_OB-fold_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04717">
        <property type="entry name" value="Phage_base_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01646">
        <property type="entry name" value="vgr_GE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03361">
        <property type="entry name" value="VI_Rhs_Vgr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phage_base_V" evidence="3">
        <location>
            <begin position="448"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="207"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="828"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="211"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="850"/>
            <end position="865"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="889"/>
            <end position="903"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV58032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="910" mass="100089" checksum="29AF40344E16C9C0" modified="2019-10-16" version="1"> </sequence>
</entry>
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    <accession>A0A518IYB2</accession>
    <name>A0A518IYB2_9BACT</name>
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        </submittedName>
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    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
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    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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            <begin position="30"/>
            <end position="54"/>
        </location>
    </feature>
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        <location>
            <begin position="75"/>
            <end position="95"/>
        </location>
    </feature>
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        <location>
            <begin position="131"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
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            <begin position="161"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="194"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="225"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="2"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="298" mass="33281" checksum="95890B961F291370" modified="2019-10-16" version="1">MSWIWLSILSALFLGLYEIAKKSAVRGNAVPPVLLLSTSTAAILWLPWIVLSQVAPDAIPNEAFRVTTLGLHEHLYLFCKSVLAGTSWIFAFFALKHLPLSIASPIRATSPLWTIAIATLWMGERPSVQQWIGVAIVLAAFYAFSFVGLREGIRFDRNRWVGCMIVATLLGALSALYDKYLLQRVGFDPSTVQAWFSIYLVAVMTPLCLYWWFRERTKSPFHWRWQIPAIAIGLLIADFLYFTAIAQPDALISVISPLRRSSILIAFAAGILMFGEVNWRAKAVCIGGLLAGVFLLSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYC7</accession>
    <name>A0A518IYC7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Serine-aspartate repeat-containing protein D</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">sdrD_3</name>
        <name evidence="5" type="ORF">Mal33_41090</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
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    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="match status" value="9"/>
    </dbReference>
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        <property type="entry name" value="Ig-like_fold"/>
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    </dbReference>
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    </dbReference>
    <dbReference type="Pfam" id="PF17210">
        <property type="entry name" value="SdrD_B"/>
        <property type="match status" value="7"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF69318"/>
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    </dbReference>
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    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
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        <location>
            <begin position="262"/>
            <end position="344"/>
        </location>
    </feature>
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        <location>
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            <end position="461"/>
        </location>
    </feature>
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        <location>
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            <end position="702"/>
        </location>
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            <end position="832"/>
        </location>
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        <location>
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            <end position="942"/>
        </location>
    </feature>
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        <location>
            <begin position="964"/>
            <end position="1054"/>
        </location>
    </feature>
    <feature type="domain" description="SdrD_B" evidence="3">
        <location>
            <begin position="1075"/>
            <end position="1164"/>
        </location>
    </feature>
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        <location>
            <begin position="1220"/>
            <end position="1285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1690"/>
            <end position="1735"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF17210"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF17802"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="QDV58092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1735" mass="185599" checksum="CDDF57E9952BDBEF" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYS6</accession>
    <name>A0A518IYS6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
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    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
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    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="295" mass="31909" checksum="D6F5F30D5237FAD7" modified="2019-10-16" version="1">MIRIVMLDFVGTLVRDDHVLPHVPAALNALRSFVTADGDPLEICLIADPAETPQHAGESEAEFFERLGELGLRQFFEPVEQRVVFVSRQELSEPNARWFHDAIDRLEIEASPSDCLMIAKAASCIAACKSQGIDTLRFGDSADAAGVDFSDWSDAPDLVAQRLGATGDTNSDAILAAALEQDLQLSDVAILQRLPGNRVSAAGNRLHPVNDPALGDCDGVSVYVPVQFDVRLDGEGKIAAVDQHPVTELDAAEAAMQLKALVDANRIAGGDGDRGKTHRIETQGEHRVLKRIRFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ02</accession>
    <name>A0A518IZ02_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA polymerase sigma factor</fullName>
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    </protein>
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    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetes</taxon>
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        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
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        <property type="protein sequence ID" value="QDV58310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000838">
        <property type="entry name" value="RNA_pol_sigma70_ECF_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014331">
        <property type="entry name" value="RNA_pol_sigma70_ECF_RHOBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="3">
        <location>
            <begin position="11"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV58310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="172" mass="19527" checksum="C074102C5D9CD308" modified="2019-10-16" version="1">MQRGDFTKIVLEHQGRIRMFIRMLGAAPDAVDDLAQDVFVIAYERLEMLEDIDQAGPWLRAIARNLVRNEARKSTRRRRVVNTSLTDVMLGLADEPDSDAWTEEWFAALKVCLEKLPQHGRALVDGRYQQGQNASQLADQTDMTPAAVRQALSRFRGLLRQCVETRFQQAGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J060</accession>
    <name>A0A518J060_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Metal chaperone YciC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">yciC</name>
        <name evidence="3" type="ORF">Mal33_47470</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SIMIBI class G3E GTPase family. CobW subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011629">
        <property type="entry name" value="Cbl_biosynth_CobW-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036627">
        <property type="entry name" value="CobW-likC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003495">
        <property type="entry name" value="CobW/HypB/UreG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02492">
        <property type="entry name" value="cobW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07683">
        <property type="entry name" value="CobW_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00833">
        <property type="entry name" value="CobW_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CobW C-terminal" evidence="2">
        <location>
            <begin position="262"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="418" mass="46772" checksum="FBDD6E76A446C296" modified="2019-10-16" version="1">MNPSVSTKRLPVTVLSGFLGAGKTTLLNHILTNRDNLKVAVIVNDMSEVNIDAALVKSGDANLSRTEEQLVEMSNGCICCTLREDLLVEVRRLARDGRFDYLLIESTGISEPLPVAETFTFEDEEGESLSMLAELDTMVTVVDAGNFMKDFGSWDELADRRMGLSEDDTRNIVDLLVDQVEFANVIIVNKTDLISPYDLEQLNRILRKLNAKAKILNTTESRCELAEIMGTGLFSLDEAEAQPEWLAVPRGQEETETEEYGISSFVYRSERPFHPKRLTEALDGDMDDGLFSGVLRSKGLMWIASRHDWAYDWSQAGCSIRMNPAGFWWAAAPDDAWPDDEALVAEIRSKFVGEHGDRHQELVFIGNAMAPQRITNILDACLLTDLEFTQGPELWANFEDPLPGIELEPGEELMEEEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J089</accession>
    <name>A0A518J089_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">K(+)/H(+) antiporter NhaP</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">nhaP_2</name>
        <name evidence="7" type="ORF">Mal33_47750</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005451">
        <property type="term" value="F:monovalent cation:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030151">
        <property type="entry name" value="NhaP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006037">
        <property type="entry name" value="RCK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036721">
        <property type="entry name" value="RCK_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32507:SF7">
        <property type="entry name" value="PTHR32507:SF7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02080">
        <property type="entry name" value="TrkA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116726">
        <property type="entry name" value="SSF116726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51202">
        <property type="entry name" value="RCK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0630">Potassium</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="57"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="90"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="164"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="194"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="232"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="268"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="298"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="334"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="367"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="domain" description="RCK C-terminal" evidence="6">
        <location>
            <begin position="403"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV58750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="606" mass="64889" checksum="289093349D51BC74" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0D5</accession>
    <name>A0A518J0D5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA-3-methyladenine glycosylase</fullName>
            <ecNumber evidence="2">3.2.2.21</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">alkA</name>
        <name evidence="2" type="ORF">Mal33_48250</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.2.2.21" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008725">
        <property type="term" value="F:DNA-3-methyladenine glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052822">
        <property type="term" value="F:DNA-3-methylguanine glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052821">
        <property type="term" value="F:DNA-7-methyladenine glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043916">
        <property type="term" value="F:DNA-7-methylguanine glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00056">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003265">
        <property type="entry name" value="HhH-GPD_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00730">
        <property type="entry name" value="HhH-GPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00478">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="SSF48150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ENDO3c" evidence="1">
        <location>
            <begin position="48"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="212" mass="23690" checksum="0D194B837C80AE31" modified="2019-10-16" version="1">MAKRLQIEAAIAHLRGADPIMAEIIEDVGPCTMRQEKDRFRMLVRSIISQQISTGAARSIRMRLDELVGPDGLTADNLARFSVDQLRTAGISAQKGKYLQDLTTKVVDGELKLQRIGRFSDAEIIDQLTIVKGIGKWTAQMFLIFSLGRLDVYPHDDLGVRSAIKKRYGLDDLPDHSTGHAIAAKWRPFASIASWYCWQSLDHDKRVAADGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0F8</accession>
    <name>A0A518J0F8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_48440</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="207"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="234"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="497" mass="57889" checksum="A049163EA7F64A37" modified="2019-10-16" version="1">MNIHTFLEHHGISRNPFAEEDAQTDPVFKEFCISSAYHPVWDKVYGDPSEPSTAIVFGAKGAGKTAIGLQIDRHLDRYNRQHLNNRTYVIRYDDFNPFLDHFQERLPRRLAKKPEKTLDAWRLWDHIDAILCLGVTRLVDRVLDQNNANDSVATEVREEDLRKLERHQARDLLLLSLAYDQSTGESFSDRWNGLRKKLGYRNWSVRWDFWLAIAGLVVALVLSGWLAYSERLSLGWSAVVFLLVSFAGSAHYKLRWLRCWWMARGIRKHMRVGKRDTHTLHKTLLSIPYSELASQPLPRFDRTDDRYEMLSKFQSVLARLGFSGVIVLIDRVDEPHLLGGKPELMRRFVWPLLDNKLLKHSGVGLKLLLPQELHRDVERETREFHERARLDKQNLIPSFHWTGEALYDLAQSRLIACAAEGQTPEPRNLFDDNISYERLLAAMQSLRVPRHLFRFLYRVLVEHCNKYTDSDPHYKIDANTFETTLAVYMKDLESTGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0G1</accession>
    <name>A0A518J0G1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Polysaccharide biosynthesis/export protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_48560</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015159">
        <property type="term" value="F:polysaccharide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003715">
        <property type="entry name" value="Poly_export"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02563">
        <property type="entry name" value="Poly_export"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="451" mass="48975" checksum="44B71DC7251177B9" modified="2019-10-16" version="1">MNVKIKNQSAKRVPASAGLLWTLCLGIAMCTGCSSLTQPINGVPARRLPPQFFAPPKNNLVPVDISLLSQEAPRNYILDSNDVLGVYIEGVLPFNAPDVTPQLPPVHFPEADSTLPPSIGFPIAIAEDGTISLPLVEPIDVRGMTIDQVRELIRQAYIKAEILKDEKARPVVTLIKERTYDVIVVRQDQQSLTTNDVNRGSEFQRGSFQGASGNIVKLPAYQNDVLHALMETGGLPGVTAKNEVKILRAGQADKLKRMETIAQHYRELENQRRQNPCLCPPAPPEDDTAIRIPLRIPPGVVPDIRPQDVLLKSGDIVYIESRDREVFYTGGLLPGGEHPLPRDYDLDVLGAMAIAGTGLGSQVNGGGGGGGLNARSVGGVPPGRLYILRKTPCEGQVAIEVDLAAATNDPRQRPLVQAGDILILQYKCEEEILNFGLGTFFTYGIQELLRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0Q2</accession>
    <name>A0A518J0Q2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Na(+)/H(+) antiporter NhaA</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Sodium/proton antiporter NhaA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">nhaA_2</name>
        <name evidence="7" type="synonym">nhaA</name>
        <name evidence="8" type="ORF">Mal33_49510</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>2 H(+)(out) + Na(+)(in) = 2 H(+)(in) + Na(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:29251"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015081">
        <property type="term" value="F:sodium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006885">
        <property type="term" value="P:regulation of pH"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01844">
        <property type="entry name" value="NhaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023171">
        <property type="entry name" value="Na/H_antiporter_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004670">
        <property type="entry name" value="NhaA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30341">
        <property type="entry name" value="PTHR30341"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06965">
        <property type="entry name" value="Na_H_antiport_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0050">Antiport</keyword>
    <keyword evidence="3 7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0915">Sodium</keyword>
    <keyword evidence="7" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="16"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="116"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="147"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="175"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="203"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="228"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="295"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="355"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="389"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV58926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="438" mass="46364" checksum="01C2B4A65DEC09F1" modified="2019-10-16" version="1">METNQSDSARRIDLRFFFENSLFLVLGAAIALIWANVANSQGSDAYNAFVHWDIAQFLGLSHGHAHAAEAGGHHGFTIHFLVNDILMALFFAIAAKEVWEALLPGGPLSNLRKAATPLLATLGGVAGPAIVYLAGTTLLGRNDTLGAGWAVPCATDIAFSLLVARMIFGGGHAAISFLLLLAIADDAIGLMILAVFYPSAETNFAWLGFTVAAVASGMAMNRAGVRNFWWYLAIPGVLSWVSFYMAGIHAALGLVPIIPTLPHAKTDLGFFAKAEDARTDTLNAFEHWWKHPVELILGMFALVNAGVVFSSVGAGTGLVLLGLFVGKPLGIGLMTLLAVRSFKLEMPEGMNMRHVVVLGCIASLGFTVALFVSTAAFPMPGPIQDSVKMGALMSFLAPVSAFAMAMALGIRPACFGKRKPAAATQARKPPKAHKQHAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0R6</accession>
    <name>A0A518J0R6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_49530</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010869">
        <property type="entry name" value="DUF1501"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07394">
        <property type="entry name" value="DUF1501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="467" mass="51000" checksum="093606D3F67A4A6C" modified="2019-10-16" version="1">MNHPFRSNDNSLARRTFLRRVGLGSVALSSLLDGEAGAATLADVPHHRARIKRVIHLCMAGGPSHLETFDNKPELARLDGQPMPESLTAGQPIAQLQNRALKVMGPQHPFVRQGKSGLEMSSVFKHLGQLADEMCVIKSMHTEQINHDPAHTFFNTGTAISGRPSMGSWVLYGLGAETQNLPGYIVLTSEGGGQSQPISSRQWHSGFLPSQHQGVQLHATGNPVHYVGNPAGVGPSQQKEIVDAIARIDSHRNEVLDDPEIATRIKTYEMAFRMQASVPELTEMSDESQKTIEMYGCTPGDGSFGSNCLLARRLAERGVRFIQLYHRGWDHHGGVKAGVAKTASLVDQGTTALVQDLKQRGMLDETLIVWGGEFGRTPMAQGSGRDHHIKGFSIWLAGGGVRGGTAYGATDDFGYNAVENKVHVRDFHATMLHMLGIDHHRFTYKFQGLDFKLTGVEEAHVVKDILS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0Y0</accession>
    <name>A0A518J0Y0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_50260</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="222" mass="25285" checksum="0D975440D396EFFB" modified="2019-10-16" version="1">MPSSPSDTTYDNLPLDQWLEECRSLFGDAPRVFDRRTERYLLVDPPWVTKLRFGDPLAKLVQNRTLRTLFRTGIVIWGHIVQANNELFEPAPSSESYTYDRPGELLFSPRDTSGTPGTLDRIASELFGLKTESSLDGELQAWAEYLNAETTRVVERRVPVQVAGSQEFYVSTSLFRRSHLPEGVLRQPLLPIVVAAHTPLFAMPLPHPYWPKSLLNWWSTGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0Y3</accession>
    <name>A0A518J0Y3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ACT domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_50280</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004072">
        <property type="term" value="F:aspartate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027795">
        <property type="entry name" value="CASTOR_ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018717">
        <property type="entry name" value="DUF2241"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10000">
        <property type="entry name" value="ACT_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13840">
        <property type="entry name" value="ACT_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ACT_3" evidence="1">
        <location>
            <begin position="2"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="ACT_7" evidence="2">
        <location>
            <begin position="72"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV59003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="151" mass="15934" checksum="BB6BAE076B9D63DE" modified="2019-10-16" version="1">MSGITDLQTLLAGLKPILVPGDYVFVTLPEAKFGDGAELEPIAAFTETEGMTLVIPKALAGKSGQQSSGEFRMITLQVHSALDAVGLTAAVADALTKRGISANIIAAYYHDHVFVPSSRADDALDALKAFANASADRASRTEVQREERKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J177</accession>
    <name>A0A518J177_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_50900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="97" mass="11035" checksum="DB3F224AEA41DD14" modified="2019-10-16" version="1">MQNLCDRSTLLGVRLCLGKSAEIETMNRLGDRHRSSSCTRGQEAINRRDLLHGDRPPVTREDGGPFFDYAHDLAYRWVAMIRSADVLAVETSRMRTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1C3</accession>
    <name>A0A518J1C3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_51690</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="161" mass="16919" checksum="CF3DAA3392CB5C8A" modified="2019-10-16" version="1">MVIQPMAIAHAGCAQGACCNAQTRCNACNSCEVGTDGGLCGCCSRIESKPSGCCDKTPGKEQRDDTSEGSVGKLSPGDGEDLTNGQPSFSSCRCGVRSEPIAPAPQRSPVSQERDLVVIAYLDHTESDSGLSILPDHGTLRLPIGSLAPHFSQRILCIWRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1D6</accession>
    <name>A0A518J1D6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase</fullName>
            <ecNumber evidence="9">2.4.2.43</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">arnT_2</name>
        <name evidence="9" type="ORF">Mal33_51870</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.4.2.43" evidence="9"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0103015">
        <property type="term" value="F:4-amino-4-deoxy-L-arabinose transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000030">
        <property type="term" value="F:mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006493">
        <property type="term" value="P:protein O-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003342">
        <property type="entry name" value="Glyco_trans_39/83"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02366">
        <property type="entry name" value="PMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 9" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="82"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="107"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="133"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="165"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="283"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="333"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="371"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="396"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="425"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="457"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="483"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="domain" description="PMT" evidence="8">
        <location>
            <begin position="11"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV59159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="636" mass="68700" checksum="29A4961C357AC21F" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1I9</accession>
    <name>A0A518J1I9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glycerol-3-phosphate regulon repressor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">glpR</name>
        <name evidence="5" type="ORF">Mal33_52260</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014036">
        <property type="entry name" value="DeoR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001034">
        <property type="entry name" value="DeoR_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018356">
        <property type="entry name" value="Tscrpt_reg_HTH_DeoR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00455">
        <property type="entry name" value="DeoRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08220">
        <property type="entry name" value="HTH_DeoR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00420">
        <property type="entry name" value="HTH_DEOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00894">
        <property type="entry name" value="HTH_DEOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51000">
        <property type="entry name" value="HTH_DEOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH deoR-type" evidence="4">
        <location>
            <begin position="2"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV59198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="255" mass="27568" checksum="E407A462EC0D89EF" modified="2019-10-16" version="1">MKTNRHEEIMKVLAESGTLSVEEAVARFGASVATVRRDFVEMAEANLVRRVRGGIQVLHNEQTMPIAIREVQQREAKLAIAREAVTMLAPGNVVFIDGGTTTLQIGSCLPGIPLRLITNSLRLAAAIESQSTRRAVHELFLTGGFLFPGTGLLVGPSAQASISQYHAQWTMLSVSGINQSGLYNDNEHVVESERLMIAGADRVVVLADHTKIGKHSMCHIAGLDEIDVIVTNRHPDTVDALEAFENAGVEVLVAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1K5</accession>
    <name>A0A518J1K5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_52510</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010869">
        <property type="entry name" value="DUF1501"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07394">
        <property type="entry name" value="DUF1501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="472" mass="50656" checksum="867A3135D14D9C30" modified="2019-10-16" version="1">MSANTSHLSVGSRRRWLQTCSSGFGMLALSSMQRQATAAATVPVVNPKAKSVILCYMSGGVSHVDSFDPKPQLVKDHGKSMPVKVERTQFNNNGKIFGSPFAFKPYGESGLEISEIFPEIGSCADHLAVVRSATTNVNEHAQGNFAIHTGFPFLGHPSAGAWISYGLGAANENLPSYVVLQSGGAVPPHGGVGLFSSGYLPAQHQASILQADKPDAVPNIRPAQTLAMQRQRLDFVRQIDSQFADSAQNRQVDAAIENYETAFRMQSAVPELCDISDETAATMNLYGIDSGDQALAAYGRQALLARKLVEQGVRFIELSCITRGIGAGGAANPWDQHGDLEKGHRAMAEQVDRPIAALIKDLEARGLLDETLIVFTGEFGRTPFSQGAGGRDHNPFGFSLWLAGGGIRGGTAYGATDELGYRAVEKPCTIYDVWATVLHQLGIDHEKLTFRSGGRDFRLTDVHGNVLTEIIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1W7</accession>
    <name>A0A518J1W7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_53580</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="43" mass="4352" checksum="1E76C46B9068D2AF" modified="2019-10-16" version="1">MCSKEKAKCYDSVSPIGGSMQSAIGFPSSVSVSLGDGQATIAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J210</accession>
    <name>A0A518J210_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_53890</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="139" mass="15244" checksum="A260C6D95C53FDA6" modified="2019-10-16" version="1">MANTLATRKQSEAIRHQMQVIRTALPHDVDAARAQAHDLLDWRYHMRKNPWPLLTVASIVGYIVVPAKTNRQTVVHTRSAVNEPAPSPPKKSMLGGVMGAVFTLALRSGMTMATRQLSQVLTSRTSGFGSHNSTTPQAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J246</accession>
    <name>A0A518J246_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">4-oxalmesaconate hydratase</fullName>
            <ecNumber evidence="1">4.2.1.83</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">galB</name>
        <name evidence="1" type="ORF">Mal33_54490</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="4.2.1.83" evidence="1"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047584">
        <property type="term" value="F:4-oxalmesaconate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003737">
        <property type="entry name" value="GlcNAc_PI_deacetylase-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024078">
        <property type="entry name" value="LmbE-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12993">
        <property type="entry name" value="PTHR12993"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02585">
        <property type="entry name" value="PIG-L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102588">
        <property type="entry name" value="SSF102588"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="254" mass="28344" checksum="39F625E27085E22A" modified="2019-10-16" version="1">MPSVLAIAAHPDDIEFVMAGTMLQLARRGWDLHYMNVCDGSRGSTRLSETECAATRLGEAQQAAKVLGATFYGPVARDMEVLYLPEYYSKIAAVVRRSKASIVLTHSPVDYMEDHETVCRMAVTAAFMHAMPNFVTDPPEATYDEPVTVYHAQPHGNKTPMGEPVVPHFYVDTTDVIDQKFEALGCHESQRAWLDSSQKMDSYTETMRTIGREVGRMSGKFEYAEGWRRREHWGFCGPDDDPLRAALGDVSVDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J252</accession>
    <name>A0A518J252_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator PleD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_54480</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041657">
        <property type="entry name" value="HTH_17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12728">
        <property type="entry name" value="HTH_17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="68"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV59413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="190" mass="21315" checksum="FCCFE6A44D71A6CD" modified="2019-10-16" version="1">MKVFTTGQVAKICKVAPRTVSKWFDSGRLKGYRIPGSQDRRIPREYLIKFLKEHGMPLGDLEDEAMAKCLIVAQDQVLIENLKRELPPEKSFKVAVAASGFEAGIQAESFSPDCIIVDFSIGKVEAVQICQNLRRNMEFAEVILIALLPDDGQPMSFDRSAINETFKKPFDARLLAERLQTLVGTKKELV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J291</accession>
    <name>A0A518J291_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">FtsX-like permease family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Mal33_54890</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="361"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="404"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="448"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="493"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="531"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="577"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="859"/>
            <end position="886"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="906"/>
            <end position="934"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="954"/>
            <end position="976"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="8">
        <location>
            <begin position="891"/>
            <end position="986"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="212"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV59454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="997" mass="105877" checksum="B7FA3FCE1F2364A8" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J2D2</accession>
    <name>A0A518J2D2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_55330</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
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            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022133172" evidence="2">
        <location>
            <begin position="24"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="141"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV59498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="176" mass="18973" checksum="093C920FE285084B" modified="2019-10-16" version="1" precursor="true">MKRSAFLLLLAAVAIVANLPARSIGQQEAGTTPVANDLPGDEQESAAGEASDAAQIDGELGSGSGVETQRLPPGYSEIITNSQRRKIYQIQQGYQSQIDVLQRQIAALVATRDAEIGAVLDPQQQQVLKFILEIRERNRTEMEQTISTQRGLEPPAANGPVPTEPSLEDTELTPIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J2E5</accession>
    <name>A0A518J2E5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Alanine--tRNA ligase</fullName>
            <ecNumber evidence="9">6.1.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Alanyl-tRNA synthetase</fullName>
            <shortName evidence="9">AlaRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9 11" type="primary">alaS</name>
        <name evidence="11" type="ORF">Mal33_55370</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + L-alanine + tRNA(Ala) = AMP + diphosphate + L-alanyl-tRNA(Ala)</text>
            <dbReference type="Rhea" id="RHEA:12540"/>
            <dbReference type="Rhea" id="RHEA-COMP:9657"/>
            <dbReference type="Rhea" id="RHEA-COMP:9923"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78497"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="9">Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.7" evidence="9"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004813">
        <property type="term" value="F:alanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006419">
        <property type="term" value="P:alanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00036_B">
        <property type="entry name" value="Ala_tRNA_synth_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002318">
        <property type="entry name" value="Ala-tRNA-lgiase_IIc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018162">
        <property type="entry name" value="Ala-tRNA-ligase_IIc_anticod-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018165">
        <property type="entry name" value="Ala-tRNA-synth_IIc_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018164">
        <property type="entry name" value="Ala-tRNA-synth_IIc_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023033">
        <property type="entry name" value="Ala_tRNA_ligase_euk/bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003156">
        <property type="entry name" value="DHHA1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018163">
        <property type="entry name" value="Thr/Ala-tRNA-synth_IIc_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012947">
        <property type="entry name" value="tRNA_SAD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02272">
        <property type="entry name" value="DHHA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01411">
        <property type="entry name" value="tRNA-synt_2c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07973">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00980">
        <property type="entry name" value="TRNASYNTHALA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00863">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101353">
        <property type="entry name" value="SSF101353"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55186">
        <property type="entry name" value="SSF55186"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00344">
        <property type="entry name" value="alaS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50860">
        <property type="entry name" value="AA_TRNA_LIGASE_II_ALA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 9 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 9" id="KW-0820">tRNA-binding</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II_ALA" evidence="10">
        <location>
            <begin position="1"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="562"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="566"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="664"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="668"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QDV59502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="937" mass="102637" checksum="8A455DD4371F5B8A" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ILY7</accession>
    <name>A0A518ILY7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GDP-mannose-dependent alpha-(1-6)-phosphatidylinositol monomannoside mannosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">pimB_1</name>
        <name evidence="3" type="ORF">Mal33_00510</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
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    </dbReference>
    <dbReference type="GO" id="GO:0016757">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="52"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="197"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="408" mass="46524" checksum="6F5D4AC93A4ABB2A" modified="2019-10-16" version="1">MKNVALIHEWLTTYAGSERVVEQMLLQYPESDLYAVANILSDKDREFLRGKEPTTSFIQKLPFLKKFLRHYLPLMPMAVEQWDLSAYDVILSSNHAVAKGVICGPDQLHVSYVHTPIRYAWEFQAQYLRESKLTWGVRSVVTRMILHYMRMWDNVSSTRVDAFVANSQFIANRIQKCYGRTAEVIYPPVDVDAFAPNYNKEDYYIAASRLVPYKRVDLIVEAFRLMPDRKLLVVGDGPMFKTLKANCPDNVELLGYLPHEKMLRLMQGAKAFVFAAEEDFGITSVEAQACATPVIAYGRGGSLETVVEGVTGCFFEEQVPESVAAAVDAFEQQQSQFDLQATRKHAEGFRPERFRAELAEFIDSEWRKFVQHRRRRPKRSITSSVPDPLNCPVVKSPDLVNFAGVSSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IM10</accession>
    <name>A0A518IM10_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ribulose-1,5-biphosphate synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_00460</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetia</taxon>
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    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039650">
        <property type="entry name" value="HdrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43498">
        <property type="entry name" value="PTHR43498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="513" mass="54177" checksum="DD50A3089DB5152B" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMD1</accession>
    <name>A0A518IMD1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_01750</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="298" mass="32837" checksum="22A3F7A4ADD55A81" modified="2019-10-16" version="1">MKFSSQGTVGLLSAMLLLVVVGIGVAASGPAADEAGIESTQCTIECKDVGESSGVAASWRHEGILWTHNDSGDSPRLFAMDQQGRHRQEVEISGAKHVDWEDIASYELDGRPQLLIADVGDNGRRRKEVVCYRVNEPKLGNKRIKVDQIWRIQYPDGPRDCEAVAVDVQERVILLASKVRNFAADVYSVPLETGEKDAKVMATRVGTIAMPMITAMDIDPRDGRIVVASYVDAMIFPRKQVAGGGKTDWEATFAQTPTLLRTPWRRQGEAICFDRHDDAVWLTSEKKPAPLIRVAIPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMG3</accession>
    <name>A0A518IMG3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_02130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022153704" evidence="1">
        <location>
            <begin position="25"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="107" mass="12996" checksum="3C607B92E03916B0" modified="2019-10-16" version="1" precursor="true">MIRRCLIAAFVAVAFCCVTEQADAQQQAYGQNWGGANGSRDWNRFYHYPYVYYPQNFYAPQYFQSADDLYHRYPQEMRIPVYNKKWHNYYPAGRRYHYGHHFILDVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMX0</accession>
    <name>A0A518IMX0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_03890</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="100" mass="11163" checksum="A157DE9B851DCB42" modified="2019-10-16" version="1">MKTKWLAGLLNHSINNPLSRSHSVFSFNLTASPLGCATLQSRGDAHAVKLEAFGSLCRWRMQISDAVFQAVELLHFVLVQNAVEYAQVVHVSDVRRTQNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IN19</accession>
    <name>A0A518IN19_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cytochrome c-554</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">cycA1</name>
        <name evidence="3" type="ORF">Mal33_04390</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Cyt_c-552/4"/>
    </dbReference>
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        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
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        <property type="entry name" value="Multihaem_cyt_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13435">
        <property type="entry name" value="Cytochrome_C554"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48695">
        <property type="entry name" value="SSF48695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome_C554" evidence="2">
        <location>
            <begin position="480"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="630" mass="67266" checksum="8DFCDBE705C2A741" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IN87</accession>
    <name>A0A518IN87_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NAD_binding_9 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_05000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
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    </dbReference>
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        <property type="entry name" value="HpyO_NAD-binding"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13454">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD_binding_9" evidence="1">
        <location>
            <begin position="5"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="474" mass="51914" checksum="84714916FA0F18D9" modified="2019-10-16" version="1">MQTTAIIGGGFSGTLAAVNLARFATTPQRVVIINSGRPFGRGTAYGTTRGEHLLNVAARNMSAFPDHPSHFFDWLRSRCDYDGLSDDVLRETFIPRRIFGDYVRGLASHYLGGADPRSQVECQVVEDSAVDIQPRGENGGVVMLEHGDPIEAESVLLATGNQPPAGLPGSGKLANDRRYCGNPWTAWHENLPDDDKHIVILGTGLTAVDVIVTLRHKGWNGKITAISRNGMLPQRHFRGIAWPTSIPDDGQTRSLKELVSLIRQDCQRLRGASQNPAIAVDKLRSRTQMLWRNLSIDEKRQFLKDYAADWNVIRHRIAGPIHDAVTDSLDCGQLTILPATIESLDAGETSIEVQLAAGGDGPDRIHGDMVINCTGPKSRFSDSQIPLYRALFDRGIAKPDAMDMGIAVTDDFAVVGDDDRPSPFLYAIGPILKGTLWETIAVPELRQQAMAVVQTILKQKPIRVASPETIEYCI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INC2</accession>
    <name>A0A518INC2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Nitrogen regulatory protein P-II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">glnB_2</name>
        <name evidence="4" type="ORF">Mal33_05300</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the P(II) protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030234">
        <property type="term" value="F:enzyme regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006808">
        <property type="term" value="P:regulation of nitrogen utilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002187">
        <property type="entry name" value="N-reg_PII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011322">
        <property type="entry name" value="N-reg_PII-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015867">
        <property type="entry name" value="N-reg_PII/ATP_PRibTrfase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017918">
        <property type="entry name" value="N-reg_PII_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30115">
        <property type="entry name" value="PTHR30115"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00543">
        <property type="entry name" value="P-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039144">
        <property type="entry name" value="GlnB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00340">
        <property type="entry name" value="PIIGLNB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00938">
        <property type="entry name" value="P-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54913">
        <property type="entry name" value="SSF54913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00638">
        <property type="entry name" value="PII_GLNB_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51343">
        <property type="entry name" value="PII_GLNB_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="O-UMP-tyrosine" evidence="1">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR039144-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR602187-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV54575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="112" mass="12491" checksum="73B28D5B4FE13193" modified="2019-10-16" version="1">MKKIEAIVRHFKLEDVKNALTEQGIHGMTASEVRGFGRQKGHTEIYRGTEYAVDFVPKVKIEVVCSDENLQTVVDTILETAQTGQIGDGKIFVTNLEDSIRIRTGERGEDAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INS0</accession>
    <name>A0A518INS0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_06590</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008930">
        <property type="entry name" value="Terpenoid_cyclase/PrenylTrfase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48239">
        <property type="entry name" value="SSF48239"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022048745" evidence="2">
        <location>
            <begin position="23"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="239"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="552" mass="61506" checksum="1B60F5042AAA8C1C" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INU6</accession>
    <name>A0A518INU6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Type I phosphodiesterase / nucleotide pyrophosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_07210</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
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                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
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                <person name="Storesund J.E."/>
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                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
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                <person name="Overmann J."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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</entry>
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            <begin position="23"/>
            <end position="45"/>
        </location>
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        </location>
    </feature>
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    </feature>
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    </feature>
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        </location>
    </feature>
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        <location>
            <begin position="23"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="QDV54945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="458" mass="48020" checksum="0C10D384944B97A1" modified="2019-10-16" version="1">MEGRYDESPDSDTNGQQRYERMVLFILASVQFITIVDFMIVMPLGPQLMRTLQINPTQFGLIVSSYTFAAGVAGIVASSLADRFARRTTFLVLFAGFLLGTLCCGLAASYGVLLWARVVTGAFGGVLGGIAMAIIGDVFPEQRRGRATGTLMTGFALASVAGVPFGLVLGTNFGWQIPFIVLAVGGGPILILARVALPRLDSHIHDVQTNPLKSLVETFAHRNHLRAFALIVALMIGSFTVFPYLSAYLVSNVGMSENQLPLIYIVGGALTFVAAPIVGRLADHYGKRRIYRIVAPASALMLFVVTHLPATHVAIAVAAFGGLMVCNVGRMIPAMAIVTSSVRPERRGAFLSANSSVQHVASGIGAYLGGLIVVEAGDGKLENFGTVGWIAAAATLVTLWLVGRVEVAGDINPLATPSAASLAIAAAAEASVDAGEALVGLSGEHQIVKDVSTNVPVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPB3</accession>
    <name>A0A518IPB3_9BACT</name>
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        <submittedName>
            <fullName evidence="3">GDSL-like Lipase/Acylhydrolase</fullName>
        </submittedName>
    </protein>
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        <name evidence="3" type="ORF">Mal33_09020</name>
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    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
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                <person name="Bruemmer F."/>
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                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
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            <strain evidence="3 4">Mal33</strain>
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        <property type="project" value="UniProtKB-KW"/>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022015195" evidence="1">
        <location>
            <begin position="32"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="SGNH_hydro" evidence="2">
        <location>
            <begin position="50"/>
            <end position="238"/>
        </location>
    </feature>
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        <source>
            <dbReference type="SAM" id="SignalP"/>
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    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="250" mass="27315" checksum="DBE2DEFE02C13FF3" modified="2019-10-16" version="1" precursor="true">MMKLTRRNLLQSTIVAGVAASSVTTATTVSAANDSNVQSLPEGAVILFQGDSITDARRDRKKQTANQSAGLGDGYPFLIAGGLLESHPAKRLQIHNRGISGNKVPDLAKRWQADCLDLKPNILSILVGVNDIWHKLNGRYDGTVDVYESGYRELIEGTLSALPDVRVVVCEPFVLRCGAVNDKWFPEFDQRREAALRVAESMSLTVVPFQQMFDKAIDEAPPAYWAADGVHPTLAGHTLMAKTWRETVGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
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    <name>A0A518IPD1_9BACT</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
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        <lineage>
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    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
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                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="352" mass="38604" checksum="CA68A009F1FD7006" modified="2019-10-16" version="1">MRNPRLFSRLSLITMLCFGGLLATATGAILLQANSGGAAMVQSANAFLSTLDDAAKSKALLAYDAAERTKWHFIPMPTRKGLVIRDMNPAQKAAALRLLRAALSESGYEKSRRIMSLEAVLLELEGPKSKGRRDPEKYYVTLFGEPSDTQPWGFSFEGHHMSLNFVVEGGKIVDSTPQFFASNPAEIKNDVSGPLKKGTRVLRDEEQLAFDLMASLQSSQREKAIFAAEAPEEISDAGEPQPTAPKLVGISYASLNGQQQEMLRSLVDVYIDSMTAEVAADRRQIIDNDGWNDVHFAWGGALKTGIGHYYRVQGKSFLIEFVNTQPDAAGNPANHIHCVWRDLTGDFNLPAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPM0</accession>
    <name>A0A518IPM0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Flagellar hook-length control protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_10020</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021136">
        <property type="entry name" value="Flagellar_hook_control-like_C"/>
    </dbReference>
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        <property type="entry name" value="FliK-like_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02120">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0966">Cell projection</keyword>
    <keyword evidence="3" id="KW-0969">Cilium</keyword>
    <keyword evidence="3" id="KW-0282">Flagellum</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flg_hook" evidence="2">
        <location>
            <begin position="413"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="320"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="489"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="135"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="279"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="330"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="489"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="524"/>
            <end position="538"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="543" mass="55917" checksum="D3E6063A419E1903" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPS0</accession>
    <name>A0A518IPS0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ferredoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Mal33_10600</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000813">
        <property type="entry name" value="7Fe_ferredoxin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00037">
        <property type="entry name" value="Fer4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00354">
        <property type="entry name" value="7FE8SFRDOXIN"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="5" id="KW-0249">Electron transport</keyword>
    <keyword evidence="3 5" id="KW-0408">Iron</keyword>
    <keyword evidence="4 5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="6">
        <location>
            <begin position="31"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU365098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV55091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="92" mass="10528" checksum="ECDE25A2728AE947" modified="2019-10-16" version="1">MTHVVAQPCFGCKYTDCVVVCPVECFYEGEKMLYIHPEECIDCEACVPECPVEAIFHEDNVPDEWSEYTQMNADEAEKCEVITEKKEPLADE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPS3</accession>
    <name>A0A518IPS3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ferric uptake regulation protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">fur</name>
        <name evidence="3" type="ORF">Mal33_10570</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Fur family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07153">
        <property type="entry name" value="Fur_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002481">
        <property type="entry name" value="FUR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043135">
        <property type="entry name" value="Fur_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33202">
        <property type="entry name" value="PTHR33202"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01475">
        <property type="entry name" value="FUR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="165" mass="19547" checksum="9005F550B2FF21D3" modified="2019-10-16" version="1">MSDSAPLGKVAVSLTPQERFEEFLQSRGQRNTEQRRFLVDRVFSNHEHFDVDSLIEQLPRKGQENYVSRPTVYRALKEFVDAGLLRCFQLEGRSVYEHDYGYPQHDHLYCTRCQKLIEFTSEEIMKIRSQVAVQHSFRVTSHRLIIQGVCQDCSRRRKKRKQDLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPZ4</accession>
    <name>A0A518IPZ4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_11390</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="246" mass="28330" checksum="61AB036C6964B158" modified="2019-10-16" version="1">MTDSNDEETSDAWKQFEQSWRRGNPLNLWEAISTVSPVYRRDLAVEFAMIDLEWRWRLNIDNEPRDTRHYAGMLTALQLDAEHYVSMLEHEFIVRSQWGDRPTIDEMLDGFPSAGELHSVLETALDENFPVFCFLKKEDERLLEHRVKLVTSFGRQTADDADGKYSISFDKASTRCVIADANETAIAESHLEIKRIGADRILAEIHAPNTNCLAADQPLLPHQPSELRLPLKLQLENHQIFFDCGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQ12</accession>
    <name>A0A518IQ12_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L33</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpmG2</name>
        <name evidence="4" type="synonym">rpmG</name>
        <name evidence="5" type="ORF">Mal33_11440</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the bacterial ribosomal protein bL33 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00294">
        <property type="entry name" value="Ribosomal_L33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038584">
        <property type="entry name" value="L33_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001705">
        <property type="entry name" value="Ribosomal_L33"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00471">
        <property type="entry name" value="Ribosomal_L33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="SSF57829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01023">
        <property type="entry name" value="rpmG_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV55174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="54" mass="6442" checksum="27B1B3C643567522" modified="2019-10-16" version="1">MAKSNKKADTIFLVCEESGDYNYSIRRKGGGEKLRLKKYCPRLRKHTWHNEKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQ88</accession>
    <name>A0A518IQ88_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_12280</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010869">
        <property type="entry name" value="DUF1501"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07394">
        <property type="entry name" value="DUF1501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="477" mass="51771" checksum="968E0119B22426E2" modified="2019-10-16" version="1">MFQHPQLPRRQAIQAGAVGLLGLGMSHLDRLRAEGAASFESARAKNVIYIFLSGGLAQHESFDMKPDAPAEIRGEFQPIATRTPGLQICEHLPQLAARSEKWSLVRSLTHPHNEHSMGHMVMLSGRSDLPTGFSPNGPKHTDHPSIAAIAGQVTQPVNNLPPAIMLPEKLVHRSGRVLPGQFGGQMGPGTDPFLLDCCSTNRQAYGAWPEYGFHHARGSENPKGLSFGLPSLQLPSAITKGRLGSRVDLLAELQSQQRGLRKLAEVDSFDRFQERALSMLADGKMSKALDVVDADPKTLDRYGRHVFGWSLLLARRLVGAGVNLVQVNLGNNETWDTHGNAFPNLKNYLLPPMDQAVAALLDDLDASGQLDETLIVMAGEFGRTPKISHLPSAYAYPGRDHWGACQSVFLAGGGIEGGRVVGSSDQHGGWPKDSPQTPENFAATIYSALGLPRTSYWHDLLDRPMPIYHGDPMPGLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQJ4</accession>
    <name>A0A518IQJ4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Prok-JAB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Mal33_13260</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028090">
        <property type="entry name" value="JAB_dom_prok"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14464">
        <property type="entry name" value="Prok-JAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Prok-JAB" evidence="6">
        <location>
            <begin position="12"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF14464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV55355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="195" mass="22102" checksum="83110B2ED3A0F944" modified="2019-10-16" version="1">MAKLLYLRDIGPTEVGGFGISNENDLWLVEDIQLVEQVCTVVSVEFDDDSVADFFDSQVDAGRQPEQFARIWIHTHPGASPSPSGTDEETFKRCFGGVDWAVMHILAEEGNTYTRARFNVGPGTENRLRCRTVFSSEFPASDHEEWFIEYCDNVTVYDPFASSRTFADSYYESDWWEQAPSAADRWSDSLLEAGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQK0</accession>
    <name>A0A518IQK0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_13290</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="422" mass="47571" checksum="0FE3B780631C6999" modified="2019-10-16" version="1">MDEPLVQSFAKVADDLRRYIEANTVLPDPDAGFSLFVGRTRCLDNAAVSQLPGWPAGAGLKHPQELACFGYLVALSDDYGQAMHGDWKASLAANLTRDLFPIDRQSFTYRPVEVLGLAVGVNALIGQDDRLRSDFADVVRQCRERGCTDTTSSWMYWLAESTLDKSTTSRPNIGDSNLPINVAALIYWIVSRPELRSSVDPDLMLALEDVLLTQSATRGIAIRDLPNASVTLASLEVSVQRRLRSRLDETTIVPSTTKDAIELVKRISENFPLFARQLLRRRKDVKVRGKKDKQSRPTVVMSDEYDVQDSLHAILRLFFNDVRDEVWTPSYADNQNRIDFVLPDFEIAIEVKHTGHSLTQRKIADQLIVDKEYYRQDTNCKHLICFVYDPELRLKNPASIENDLSAPDDDFEVIVIVSPKGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQK8</accession>
    <name>A0A518IQK8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_13210</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="311" mass="35434" checksum="1E0D6C9E60D4A015" modified="2019-10-16" version="1">MTIAMVEPRATNTAGTSERLRSRMAAMKLMFHWLGTKKSLNAEQMSRAADAFDAERKFLSAGKKLFDTGDPDFRRVTAVKSQATTYYKSVSLPFPEPGVRLIRQDQVDTIHERMQSFREELAHAVQQLETRFSEVTLEARDRLGDLFNSSDYPTSLSDSFHIEWTFPTVEAPEYLRRLNPELYQQECDRVRAQFDEAVRLAESAFVEELGKLIDHLAERLSDSADGKVKVFRDTAITNFTEFFERFQSLNIGSNAELDALVDRARTVVSGVAPQTLRSSSELRDRITNQLANVQASLDGLMVDRPRRNIIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQN3</accession>
    <name>A0A518IQN3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Multidrug efflux system subunit MdtA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_13510</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="domain" description="HlyD_D23" evidence="3">
        <location>
            <begin position="121"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV55380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="494" mass="54750" checksum="B6EC55E99FA3C484" modified="2019-10-16" version="1">MKIRMPKVPMKWVWLVATLVAVIVGGFTWQRWFPATRAWVEQTAVSFRGGGGSHEGEAAGEADPHAGHDHAAHAGHDAATSLELSKQAIRNIGLSDETIRPIKLETFRRSITVPAVVVERPGRSRVQVATPMTGVVTHVHAVQGQAVEPGSLLFQVRLTHEDLVNAQTAFLRTLGELDVEQREVARLQQVTRSGAIAGKILLERQYALDKVNANLSAMRESLRLHGLSDKQVQQIEKERRVLRELQIFAPNIDSHGEDDLRLTQRAIQAAYVKDEQPQHIGPLTLQDLPIHKGQSVGAGETLCTLTGYDELFIEGLAFEQDIKQLRKASQNGWAVDAILEEPGPESSVIEGLEMAYIDNQVDAQSRTLKFYVRLPNEIAKDDRANGNRYVEWRYVPGQRLQLRVPVEEMPKQIVVPVEAVASEGAETFVFQQNGSHFDRVPVHVKYRDQYSAVIDNDGSLFPGDVVAMRGAHQMQMALKNKSGGGVDPHAGHNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQQ6</accession>
    <name>A0A518IQQ6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Outer membrane protein (OmpH-like)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_13920</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Skp family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.910.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005632">
        <property type="entry name" value="Chaperone_Skp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024930">
        <property type="entry name" value="Skp_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03938">
        <property type="entry name" value="OmpH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00935">
        <property type="entry name" value="OmpH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111384">
        <property type="entry name" value="SSF111384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="47"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV55419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="204" mass="22887" checksum="1D25397258E71E0A" modified="2019-10-16" version="1">MRTDSLLTLVLGAMAIGWILPQPCLAETKTSAGKFAIIDVAYIFKNAASIKAEVEAIEQQMAELQRYGKAKQQEMLKEAQAIKAFKPGSLQYAQQEEKIAALEASLKLEVFRRRKSLASAEAELYFAGYQKMHQIVSQIARYNNIDLVLRYDSESMDLEKPDTVLRSVMKNVVYRRDTIDLTQIVLAALDKTQVAAKPVASELR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQU3</accession>
    <name>A0A518IQU3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_14360</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022022380" evidence="2">
        <location>
            <begin position="29"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="132" mass="15156" checksum="5E580980B801B0A0" modified="2019-10-16" version="1" precursor="true">MLRTLRWLAVPCLCFAVVAVGDAPQAKAQTGGFSIQFGTPSYGYGGYNRSYRPSYGYGYGSSARIYSQHRSYYGGHHPHRPHYDYHRPSLVPHGNRYHYVPGHYDLHRGHHGHHGHRDHGHRDNGHRGHHRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRF5</accession>
    <name>A0A518IRF5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_16570</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="98" mass="10979" checksum="0A3B3603551988F2" modified="2019-10-16" version="1">MSEKKPTPWRVQESGKVCPICGKRTYSNGGIHPQCAVLQADSARTEKLRAERKRKANEASSNPKAKPHSTSWTQKKCPKCGKESHVRRKNCDCGHAFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRS1</accession>
    <name>A0A518IRS1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_17530</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022240298" evidence="1">
        <location>
            <begin position="35"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="468" mass="50703" checksum="1EE0C9FE8A7903AF" modified="2019-10-16" version="1" precursor="true">MKNPFPQELNRRGFISATAAATLASGIAPLPALAAESAGNLHLGTFRFDVTPPMGHSLCGGWIKPVVGVDDPLEAIGYVLLGAGKPIVVCVVDWTGLLNSAHIQWRQALADAAGTTIDRVAVHCVHQHNAPFACLDSEEIVLAQGDLPHIVERDFFLECLDAGREAVGKAMKQTTPVTHVARSQAKVDKVAGNRRLIGLNGKVISQRGSSSKNAMHHAFPEGLIDPMLKTVAFYNGDKKLAACHYYACHPMSYYGDGRVSADFCGLARKQMQKQEPDCTHMYFNGCGGNIGAGKYNDGSKEMRPILTQRILDGMVAAQESLVPEAIESIRWETEDILPPINPAFDEEALMRQISDKTQRVVHRNRPSYTVAWIRRIQAMVPITLSCMHINDVSLVHLPSESFIEYQLRAQAAAPNRFVACAAYSDGGPWYIPTADAYPQGGYAVSVAHCSAGMDPILSGGIASMLSRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRV1</accession>
    <name>A0A518IRV1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_18050</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="431" mass="48677" checksum="F6F1FFCB77C81441" modified="2019-10-16" version="1">MSPPLSRITSRWKSTTILGVLFWSGCLVAIAIAARTHRAEASRVTELATHFMRSRDRFRIELPDGPLRRGDAIFAQDASGQWTQVGHAISSDEAGSQPSAEILWYGSQPASHYGFTYCRNRGTLAEAVEILLPAERRTVILNKIAAAQRLHGPELTAAFKPIIEQTLRESVPVIQQALVRAVTAHQAEFDAIGERFEAELINQRVVPLVRSEVLPIVRTHGEPVATEIGQEIWDRASLFRFGWRIMYDKSPLPQRDLSQQEWERFMENEAIPVFESHVDQIVGAVKAILRDVVKNEAVRDEFTQVLQEVASDDQLQALAGSIVRDAIIDNQELRQVWLKNWQTAEAQQAMQLANARLEPLVREIGDEIFGTRETGISPGFARVLRNQILNKDRRWIEAQVLPTARNEDQPAIAEADDRSHPYPMLFFADRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IS60</accession>
    <name>A0A518IS60_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_19170</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008969">
        <property type="entry name" value="CarboxyPept-like_regulatory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49464">
        <property type="entry name" value="SSF49464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022054616" evidence="1">
        <location>
            <begin position="28"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="194" mass="19852" checksum="E475111103F613E1" modified="2019-10-16" version="1" precursor="true">MRNTKLLKSVVTIVTCAAMIVPQPAMAAARATQVVDGIQVSSDIKNVRRGKTVALRGAIVDQSGKPVAGAPVVIAQQGNVVAELNTAADGRYQLADAAPGVYQVASYAGVQTIRLHAAGAPADSVDGVVQVIDNEGVARGQYCAGGASCQGCDQCRPKRFALLKKVATSPLTWTAVIAAAIAIPLALDDDDDAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISA3</accession>
    <name>A0A518ISA3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sensor histidine kinase LiaS</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">liaS</name>
        <name evidence="2" type="ORF">Mal33_19480</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="1">
        <location>
            <begin position="129"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="215" mass="23628" checksum="22A5AF087CEDD63B" modified="2019-10-16" version="1">MNNQEESGKQSASELAELERTWMSHELHDGLMQWIVGAKMQSESLYARSMDGKPPTADQLQYLCTLLSRAVLEGRRLMAGLRPPELDESDWHVALTHWADIARTGGQAVVEFNLDPATRTIPDATQRCIYRIVQEAVGNALRHAKAEKVQVDANFVGDELVVSIEDNGSGFDKASVGADRYGLKGIHERASLIEGSASITSQIGSGTRVEVRLPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISG8</accession>
    <name>A0A518ISG8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Calcineurin-like phosphoesterase superfamily domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_20130</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022106973" evidence="1">
        <location>
            <begin position="36"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="domain" description="Metallophos" evidence="2">
        <location>
            <begin position="47"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="303" mass="33744" checksum="7D34AA855052E5EC" modified="2019-10-16" version="1" precursor="true">MNQQQKSKLGGRRAFMKNGTLILSAAAAAPATLLAADKPADKPAGVRVALVTDLHYADKPPGGSRHYRKTLGKLDEAAKQFEQEQPQMLVELGDLIDAADSVETESRYLQTINRPFSAICKDRHYVLGNHCVDTLKKEEFLGAVEQPKSYYSFDRGGFHFIVLDSCFRSDGQPYQRKNFKWTDANIPAAELEWLAADLKSNDKPTIVFAHQRLDVSNHHGVKNNAAVRQIFEDSGKVLAVFQGHSHRNELKEIGGIHYCTLVAMVEGGEQATNAYTLLDVQPDSTLKITGFRNQNSYLWEPQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISL3</accession>
    <name>A0A518ISL3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_20610</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="31"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="107" mass="12720" checksum="E3922E8FE246EF09" modified="2019-10-16" version="1">MQHPRTPDGRYFVVRGRLWRCTNPHLSEVERQLFVDELMAARREVKRAREAADDVALKSARQSVDKAKRALGERGPTWWDDDTDFNRCMIRNTPYANWWLERSNELC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISM4</accession>
    <name>A0A518ISM4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Type II/IV secretion system protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_20490</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GSP E family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001482">
        <property type="entry name" value="T2SS/T4SS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037257">
        <property type="entry name" value="T2SS_E_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007831">
        <property type="entry name" value="T2SS_GspE_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00437">
        <property type="entry name" value="T2SSE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05157">
        <property type="entry name" value="T2SSE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160246">
        <property type="entry name" value="SSF160246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="2">
        <location>
            <begin position="319"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="584" mass="65361" checksum="627D55FD03ED1EBC" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISN7</accession>
    <name>A0A518ISN7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_20420</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="408" mass="43999" checksum="B9C94ED54D26AB1A" modified="2019-10-16" version="1">MSKSTQKRNGITLIEVMFAMGVMLIGLLGIASVIPVAANYARQTLENDIGTVYASHAVALINSSKFLEPKDLVFVNDETTGLSSDYLRNRPRREPGNFPAAGFQVGTTPSFCIDPWFLNHALSYRDTSGSVNGFHAGVFPYYDSDYSPAVSPNATAMPTGDPNQFPRLWRVFPEIITGSPNLSRRIGGAIQSVFQNDDSLSMEFPDDPTLYPQQLAYTSQVGAASNIAVRRLSEGHYSWIATVTPSTSVIAPGAMKLSVVIIRDRVFVPHPSNPITSSSPLNYAVSADAESNPTNERLALVTGAIGFVGGLGGSVTIEASSDMNDSIKAGHWVMLSQRNFSAGQPAVHVWYEVNNVSETSPSTTFTGGWKRTVSLVGPDWPQADMTSLPTQMTIVENAIAVKEIEITL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISP8</accession>
    <name>A0A518ISP8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_21050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021748795" evidence="1">
        <location>
            <begin position="24"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="157" mass="16249" checksum="3F16D6FE135B6EDD" modified="2019-10-16" version="1" precursor="true">MVDEKKFRVPFLLVLFLSAVPLAAGCSSSDTSNTGTVAGSVNYNGSSLGEGASVVFMDMTTGFTCAGVTDAEGKFHLESINDGNLPIGSYGVMVRPGGTMDMAAMEQASSAEDAMNDAGIAKPAAVKFPSKYNDLATSGLSFEVQQGANEMQIELVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISQ2</accession>
    <name>A0A518ISQ2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RNA polymerase sigma factor CarQ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">carQ_1</name>
        <name evidence="4" type="ORF">Mal33_21000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014331">
        <property type="entry name" value="RNA_pol_sigma70_ECF_RHOBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02989">
        <property type="entry name" value="Sig-70_gvs1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="2">
        <location>
            <begin position="87"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="3">
        <location>
            <begin position="185"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV56121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="250" mass="28681" checksum="61B187CC49613212" modified="2019-10-16" version="1">MWCNWRPKIASSLQCNGYEKALGDSRDLKDLSGTIEKRKITPHEVPFNGALSRLKDERFRPPALYPLSMNSERQSKFELDGELVVLLTDAQPRLMGFLLKRLGNSDQAHEVLQEVNLVLCRRAAEYQPGTNFMAWAFTIARFQIMAFRKRQTRDLLVFPEDLANTLEAMDQQMFQPELQRSRETALRDCMGKLREEHQGLLLQRYAESLSVKAIAADFGKSVNAISLLLHRIREQLLGCIEKNLSGEIRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IT38</accession>
    <name>A0A518IT38_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Divergent AAA domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_22370</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007421">
        <property type="entry name" value="Schlafen_AlbA_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038461">
        <property type="entry name" value="Schlafen_AlbA_2_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04326">
        <property type="entry name" value="AlbA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AlbA_2" evidence="1">
        <location>
            <begin position="14"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="400" mass="44735" checksum="2E8FA183650F76F7" modified="2019-10-16" version="1">MNSDFIEQLLYEEEGPTLDFKRDQYAFAKATEEEKSELLKDIIGFVNCWRRGEAFILIGVQEVQGGKSTVHGISDHLADHSLQQFVNNLTNRPVQFGYEACECDGKQVGIIRIEMQKRPVFLKRDYGKLKKGEVYVRRGSSTDPSKPADPDEIALMGSGQAVEAKAASLSVEFAAIGLEQSLGTQIEWTAENCEMPDSNDIPLLDDRPHSVRIPGGGSIQMPNMSSLDSMYRLNETYYHDLAYYEFIRRLVKEVRLVVINTGDAPATDVRLEIAAPVGQGFNIADVSELPDVPERRTCLLSSPAMKNLHLRHVGHVAVNKNDQQMKVEIDCGNLQPGRKVWTDSFRLGIGQSGEVELKGHVFAANLTKPQEFSLKIKADIQRTSMTLDELFALDKEDDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IT67</accession>
    <name>A0A518IT67_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cation efflux system protein CusC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">cusC_1</name>
        <name evidence="5" type="ORF">Mal33_22760</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010131">
        <property type="entry name" value="RND_efflux_OM_lipoprot_NodT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01845">
        <property type="entry name" value="outer_NodT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0564">Palmitate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1134">Transmembrane beta strand</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="101"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="512"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="102"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV56294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="586" mass="64120" checksum="252C4512753AD31B" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IT73</accession>
    <name>A0A518IT73_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nmad2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_22450</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041180">
        <property type="entry name" value="Nmad2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18753">
        <property type="entry name" value="Nmad2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nmad2" evidence="1">
        <location>
            <begin position="77"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="260" mass="29473" checksum="0D0EA0EDA3D8F979" modified="2019-10-16" version="1">MKNERCGIKAAKQKSDCHTIRDTQTVQPFPASGSLADNLGVPLPVLKQEIGKDNGRAYSYVLSTVKCDHQSTTFEQHGSAPNFQGGMLTLCTCKHQMRATQSADQWNGVWIAGFTSRTIHDGKHWLFYLAKIDSAHESHADLWQAMKAHTRNAKVADRHFLGDMFRPKLPLPTGKARFLPSCYVTPTAHAHRQHRGDKGWRNDINYRHSDRYSYPPLLAADPNKTFIWDEPMIFFAGDHCRNFHKWSSLSDLVSKLKGVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITB5</accession>
    <name>A0A518ITB5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative oxidoreductase</fullName>
            <ecNumber evidence="2">1.-.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_23090</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EC" id="1.-.-.-" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="244" mass="25862" checksum="FC5CD785AD813885" modified="2019-10-16" version="1">MSVLKDKIAVVVGGGTGIGAGIARGFAEAGCRVVIAGRRIETLQTFADSVASPHPIAVRSADVADRESVDSLFAWVAETIGPVDIVCNAAGINIATRSMAQMQPEQWDQVLAINATGGYNVMNAVLPAMRARRDGLIINISSIAGKRAIQLGGIAYCASKFAMTAMGTAASNEVRDEGVRITNVYPGEVNTPLLDKRPNPVSQEHRDSILQPEDFGALMVSIASLPPRAHVPEIVLKPTTQEWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITP4</accession>
    <name>A0A518ITP4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DNA mismatch repair protein MutS</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 10" type="primary">mutS</name>
        <name evidence="10" type="ORF">Mal33_24470</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the DNA mismatch repair MutS family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1170.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00096">
        <property type="entry name" value="MutS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005748">
        <property type="entry name" value="DNA_mismatch_repair_MutS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007695">
        <property type="entry name" value="DNA_mismatch_repair_MutS-lik_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017261">
        <property type="entry name" value="DNA_mismatch_repair_MutS/MSH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000432">
        <property type="entry name" value="DNA_mismatch_repair_MutS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007861">
        <property type="entry name" value="DNA_mismatch_repair_MutS_clamp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007696">
        <property type="entry name" value="DNA_mismatch_repair_MutS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016151">
        <property type="entry name" value="DNA_mismatch_repair_MutS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036187">
        <property type="entry name" value="DNA_mismatch_repair_MutS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007860">
        <property type="entry name" value="DNA_mmatch_repair_MutS_con_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036678">
        <property type="entry name" value="MutS_con_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045076">
        <property type="entry name" value="MutS_family"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361">
        <property type="entry name" value="PTHR11361"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01624">
        <property type="entry name" value="MutS_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05188">
        <property type="entry name" value="MutS_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05192">
        <property type="entry name" value="MutS_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05190">
        <property type="entry name" value="MutS_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00488">
        <property type="entry name" value="MutS_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037677">
        <property type="entry name" value="DNA_mis_repair_Msh6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00534">
        <property type="entry name" value="MUTSac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00533">
        <property type="entry name" value="MUTSd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48334">
        <property type="entry name" value="SSF48334"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53150">
        <property type="entry name" value="SSF53150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55271">
        <property type="entry name" value="SSF55271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01070">
        <property type="entry name" value="mutS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00486">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7 8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6 7 8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5 7 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA_MISMATCH_REPAIR_2" evidence="9">
        <location>
            <begin position="699"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="625"/>
            <end position="632"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS00486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV56457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="885" mass="98152" checksum="826CA100FA4FEE85" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IU42</accession>
    <name>A0A518IU42_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ABC transporter ATP-binding protein YojI</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">yojI</name>
        <name evidence="10" type="ORF">Mal33_25990</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904680">
        <property type="term" value="F:peptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015833">
        <property type="term" value="P:peptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005898">
        <property type="entry name" value="Cyc_pep_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43553:SF11">
        <property type="entry name" value="PTHR43553:SF11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01194">
        <property type="entry name" value="cyc_pep_trnsptr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="23"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="1"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="296"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="334"/>
            <end position="341"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV56607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="512" mass="56519" checksum="9F335EA29D6E1CC3" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IU82</accession>
    <name>A0A518IU82_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_26490</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="46" mass="4494" checksum="73E9B29FD35981A0" modified="2019-10-16" version="1">MGHSCTARSVTLILAALETILRQSGSSIEPGAALAAAAQASDPANA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUD3</accession>
    <name>A0A518IUD3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tetratricopeptide repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_26680</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011717">
        <property type="entry name" value="TPR-4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07721">
        <property type="entry name" value="TPR_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="43"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="235"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="318"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="483" mass="53590" checksum="C7DD21E88723199A" modified="2019-10-16" version="1">MISFRYLFGWDTIYGMSRKNSRVARTAKPASPQQVPGSKRRTAVVGGVALVLLVLVAYLQGGFALWPLQNARSAMDRRDHASAIEALQLAEFCNGDQVSIDLLRARISLRRGDLAETELQLRRAQQHGANSRDIEREKLLAAALNGELEKIEPELKAWLESPGTDGADICDAYTHGLASQGRLEEAQLLLEAWQTGFPEDPKPHVKRARIGEYALQQDAAEEEYRRALAKQPSYAPAIYSLARLLLERKRPEEALELFQLCHKVSPDTAAAAQIGEARSLVMLGNSDDAREILQQVEDYQPQQVVVAFQRLGFQPDGDPAAFELGKLDSANGDFAAALPRLRRAVSANPHDLDARYALAIALRGQGEQAEAEKEFEYVKTVRQELAKTENLRTSLGTDPTDNEARFQVAMIYLKYQSPKLGIFWLQSVLAQDPRHWGAHDALATYYENNAARSPSFAELARRHRGLANEILAVPSESTSVVVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUF0</accession>
    <name>A0A518IUF0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_27190</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="111" mass="11843" checksum="378B16C4195090C3" modified="2019-10-16" version="1">MSAKVKIRQAAACLLLLAAIGCGETTPPVAEVTQSVYVDTDTMQAIVADTATQTPAIHPVTGKRTLQPALYCPKCERWHAIPSVEQINRKPGATRCPKTGAEMTADGPWPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUG2</accession>
    <name>A0A518IUG2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_27150</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="211" mass="22155" checksum="254B1BA7D929AEA8" modified="2019-10-16" version="1">MAVGTFGAWLGLAGRSSSNLPSPGQRPGNGDRSIRSVGPTARQFAQFGSIGEQIAGPLALAVPGRDVFPGRWPGLGKSPGLRPGTCIGCEHVTVVIYTPSPAGIADGSRRSPRRGVPPEHDAHTRAAAPEGSADRCEPPFGDGVRFRESVTGGIRYAQTTGYLLGPLRGPLASGTLRKLRSSLDHSFAQRRRYLSGSLLQQDFSGNAQLVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUV2</accession>
    <name>A0A518IUV2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_28630</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="150" mass="16557" checksum="7CB9671436FA93CC" modified="2019-10-16" version="1">MPITDYRRRFLIKASLSLAATTLPGCGTIFFPERVGQPRGGPIDWKVVALDGVGLLLFVVPGIVAFAVDFYNGTIFLPSYNYSQIESQRTDELLAVEIEKSELSQAKVEEIVSNHVDQEVELSAGKYRANPLPSMDQFWGLAGKMRAAFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IV31</accession>
    <name>A0A518IV31_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative uridylyltransferase</fullName>
            <ecNumber evidence="3">2.7.7.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_29310</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UDPGP type 1 family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.-" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070569">
        <property type="term" value="F:uridylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018551">
        <property type="entry name" value="DUF2007"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011322">
        <property type="entry name" value="N-reg_PII-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039741">
        <property type="entry name" value="UDP-sugar_pyrophosphorylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002618">
        <property type="entry name" value="UDPGP_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11952">
        <property type="entry name" value="PTHR11952"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09413">
        <property type="entry name" value="DUF2007"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01704">
        <property type="entry name" value="UDPGP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54913">
        <property type="entry name" value="SSF54913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DUF2007" evidence="2">
        <location>
            <begin position="473"/>
            <end position="536"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="540" mass="57615" checksum="5D250E8E8DA1C7CF" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IV37</accession>
    <name>A0A518IV37_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_29600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022161029" evidence="1">
        <location>
            <begin position="24"/>
            <end position="585"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="585" mass="62706" checksum="E778E0ECBBC55750" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVY7</accession>
    <name>A0A518IVY7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Prephenate dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_32550</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008977">
        <property type="term" value="F:prephenate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004665">
        <property type="term" value="F:prephenate dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006571">
        <property type="term" value="P:tyrosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003099">
        <property type="entry name" value="Prephen_DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02153">
        <property type="entry name" value="PDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51176">
        <property type="entry name" value="PDH_ADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Prephenate/arogenate dehydrogenase" evidence="1">
        <location>
            <begin position="12"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="298" mass="31699" checksum="0002409DF5299160" modified="2019-10-16" version="1">MNREAQEAWRPRRIAVIGVGLLGGSVALAAKRRWPDATLVGSSRKPETRQTMLDLQVVDHAFADAIECVADCDVIIIAAPVGHIARLLPEIADASDPNAIITDVGSTKHEIVTAAESHPAAALRFVGSHPIAGSERTGVENASVDLFQGKLSITTPTDQTDPIRHDRVKQFWGEIGCRVISMSPADHDLALASASHMPHIASAALALALPQEFAHLTGSGFRDATRIAAGDPLMWRQIVEANAPAVLAQLQQYESAIGQFRGAIASQDWAGIEKLFADAQTAKQTIDAATCGPEDDSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVY9</accession>
    <name>A0A518IVY9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_32540</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="181" mass="20898" checksum="B3A4045D63539C09" modified="2019-10-16" version="1">MTEKRDSAPSTLLQRFFSGVSESIFHGQLGVVDVQLVDYINSLLIRFVRTDMLHTVRRATGRPATEVVEMLIEADKRIGVARREVHRHVGDFTLFWSGMYPESLRQMKSRDHADHFVDYCQQGKRAYAIASSIEGGDDRPPCDLLRRLSEQFEMCAYGLREVRRELENRDGDPPHQKTLLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IW65</accession>
    <name>A0A518IW65_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Gnt-II system L-idonate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">idnT</name>
        <name evidence="2" type="ORF">Mal33_33380</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015128">
        <property type="term" value="F:gluconate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003474">
        <property type="entry name" value="Glcn_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30354">
        <property type="entry name" value="PTHR30354"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02447">
        <property type="entry name" value="GntP_permease"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="120"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="155"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="195"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="245"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="338"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="371"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="421"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="460"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="501"/>
            <end position="522"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="527" mass="54633" checksum="536EBCB5EF71C5CA" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWE9</accession>
    <name>A0A518IWE9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase IS200 like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_34160</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002686">
        <property type="entry name" value="Transposase_17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036515">
        <property type="entry name" value="Transposase_17_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01797">
        <property type="entry name" value="Y1_Tnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01321">
        <property type="entry name" value="Y1_Tnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143422">
        <property type="entry name" value="SSF143422"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Y1_Tnp" evidence="1">
        <location>
            <begin position="5"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="155" mass="17838" checksum="DAC5C8F0E0C99C53" modified="2019-10-16" version="1">MSSTHTNLLFHIVYSTKYRRDMIGADVQPRLYEYIGGVVREHKGILLEVGGMPDHVHLLAKLSPAVAISDVLRFVKANSSKWVNETLAPKLPFAWQRGFGAFSVSASNVPEVTNYIQTQAEHHRKLTFRDEYRALLERHGIEFDERYLFEEEHVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWF2</accession>
    <name>A0A518IWF2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Xanthan lyase</fullName>
            <ecNumber evidence="2">4.2.2.12</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">xly_4</name>
        <name evidence="2" type="ORF">Mal33_34310</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="4.2.2.12" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047492">
        <property type="term" value="F:xanthan lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039650">
        <property type="entry name" value="HdrA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43498">
        <property type="entry name" value="PTHR43498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021731884" evidence="1">
        <location>
            <begin position="24"/>
            <end position="692"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="692" mass="77503" checksum="AD332325E601E7AF" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWI8</accession>
    <name>A0A518IWI8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Dihydrofolate reductase</fullName>
            <ecNumber evidence="3">1.5.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">dhfrIII</name>
        <name evidence="5" type="ORF">Mal33_34700</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 5,6,7,8-tetrahydrofolate from 7,8-dihydrofolate: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the dihydrofolate reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.3" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00077">
        <property type="reaction ID" value="UER00158"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004146">
        <property type="term" value="F:dihydrofolate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006545">
        <property type="term" value="P:glycine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00209">
        <property type="entry name" value="DHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012259">
        <property type="entry name" value="DHFR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024072">
        <property type="entry name" value="DHFR-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001796">
        <property type="entry name" value="DHFR_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48069">
        <property type="entry name" value="PTHR48069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00186">
        <property type="entry name" value="DHFR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53597">
        <property type="entry name" value="SSF53597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51330">
        <property type="entry name" value="DHFR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DHFR" evidence="4">
        <location>
            <begin position="1"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV57460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="139" mass="15776" checksum="A88640A5FD4C4ADB" modified="2019-10-16" version="1">MPWQLSHDLRRFKRLTMGSILIMGRKTFDSIGRPLPGRTTFVLTRDQSWAHPGVEAFTDPDVMLAAVGDRSAYVVGGAQIYTAMMPACHHLYLTRVWSQVVGDTAIEIDLHDWRCRFVERIPAGSRDSIPSEFSVWDRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWV5</accession>
    <name>A0A518IWV5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">GFO_IDH_MocA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_35790</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021908938" description="GFO_IDH_MocA domain-containing protein" evidence="1">
        <location>
            <begin position="30"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="domain" description="GFO_IDH_MocA" evidence="2">
        <location>
            <begin position="87"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="351" mass="37297" checksum="E6BE82111B7B309F" modified="2019-10-16" version="1" precursor="true">MQIPTLAQLALIPALAAAVSLSAATSASADEPLKVGIIGLDTSHVTAFSKVMNDPKATGDLAKMSVVAAFPGGSPDIASSRDRVEGFTNQLRDMGVEIVDSIPALLEKVDVVMLESVDARPHLEQVLPVFKAGKRVFIDKPLAASLVDCLAIQQLSKKYDVPFFSSSSLRFSPDIYRFRTGDPKVGAVLGATVWSPCSLEPTHPDLFWYGVHGVETLYTIMGTGCTQVSRVSTADTDEATGVWEDGRVGTFRGLRAGKRGYGGIVFGEKSIADAGTYAGYQPLVQRVASFFLTGEVAVDPNETIEMFAFMTAADESKKKDGAAVSIADVMKAAEAQVADRIAEVEKKIAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWW2</accession>
    <name>A0A518IWW2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Type IV leader peptidase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_35650</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase A24 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000045">
        <property type="entry name" value="Prepilin_IV_endopep_pep"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01478">
        <property type="entry name" value="Peptidase_A24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="69"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="117"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="149"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="200"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="257"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="283"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="316"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="340"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="366"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="390"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_A24" evidence="3">
        <location>
            <begin position="264"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV57555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="427" mass="46736" checksum="6AFB3D059C967651" modified="2019-10-16" version="1">MTYLLIVLVGVVLGAFINWAIYSWAWFPRAISPWSKADDRALPRTWSDRIPVFGWFGLRRETEIHGRIFWLRPMLIELLFGPMLAGLFWWEVIELGLLPSGAAAGMPPGMLAVTQQWMLIMYLGHALLMTLLMIATFIDFDEQTIPDAVTVTGTLLALALHVIAAMMMPQIGSPLCLPWATEGGLAAVMFTAPAPIETKWLTPMGLIVGEAIFAAWCFALANRRWIMRKGFVKAIQFFAAGLVKYETMLLGRFRTKVWKLLVAIWLTGSVAIAAVYFGLGGSAWLALLSALVGVGLGGGQIWAVRVFAKLGLGKEAMGFGDVTLMAMVGGFLGWQAALFVFFLAPFTAIAIVLASWLLTGNRMLPFGPYLAAGAVLTVVFWDAIWNQWGAGVFILGPLIGAVLLLALVAMCALLFLFRVVEQKIFAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IX55</accession>
    <name>A0A518IX55_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_36800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008965">
        <property type="entry name" value="CBM2/CBM3_carb-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036439">
        <property type="entry name" value="Dockerin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49384">
        <property type="entry name" value="SSF49384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63446">
        <property type="entry name" value="SSF63446"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="170"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="195"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="618" mass="64097" checksum="96F2D7B00E0B0691" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IX92</accession>
    <name>A0A518IX92_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_37170</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010869">
        <property type="entry name" value="DUF1501"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07394">
        <property type="entry name" value="DUF1501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="489" mass="54028" checksum="0CCEA5A4A4D67088" modified="2019-10-16" version="1">MLSIKGAAGKDLCDPSLKRSRRDVLRIGGSGMLGLSLGSMLNLQAQASETPLGGGPGWGKAKSVILVYLQGGPSQLDLWDPKENVPDNVRSVFKPISTKIPGIQFTENLPRLAQLNDRFTMIRSMSYTPNGLFNHTAAIYQMMTGYTTDKVSPSGQLEPPSPKDFPNFGSNLIRLRPVDEPMLPFVMLPRPLQESNVVGKGGSAGFLGKSHDPYTLYPSGDDMDMEKMSRIKIDDLMLRPEVFSVRLQRRARLRDLINQQMPTINKAVESYELDEYYDRALSLIVSGRAREAFDLASEPVALRERYGQNTFGQSCLLARRLVEAGTRVVEVIWPKVANSDNHSWDQHSGLSKRMKDQSAPMFDAGFSSLIEDLDDRGLLDETLVVGVGEFGRSPQRGVSTSGNNNSADGRDHWPYCYTCVLAGAGIRRGYVHGKSDKTASAPLEDPVHPGELLASIYHSFAIHPETMVYNHLNQPRELVKAQAVTKLYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXA9</accession>
    <name>A0A518IXA9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PSP1 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_37300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007557">
        <property type="entry name" value="PSP1_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04468">
        <property type="entry name" value="PSP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51411">
        <property type="entry name" value="PSP1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PSP1 C-terminal" evidence="1">
        <location>
            <begin position="56"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="181" mass="19867" checksum="2E1CABF793B771E9" modified="2019-10-16" version="1">MISHYLVRTGAWGDISQHRPVDGGSYRRGDRVICETSRGLEIGEVVADVDAEASGGRILRRMTDQDELLQQRLERYKRKAVQECRDKLVAAKIDAVLLEVEQLFDGRTLYFHFLGETDSDVEAITNELADAYEQHVRSRHFAKLLREGCGPDCGTKEGGGCSGGCAVCVVASACSSTAKKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXC0</accession>
    <name>A0A518IXC0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATPase family associated with various cellular activities (AAA)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_37470</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011703">
        <property type="entry name" value="ATPase_AAA-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041628">
        <property type="entry name" value="ChlI/MoxR_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07726">
        <property type="entry name" value="AAA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17863">
        <property type="entry name" value="AAA_lid_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_3" evidence="1">
        <location>
            <begin position="49"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="AAA_lid_2" evidence="2">
        <location>
            <begin position="248"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="328" mass="36825" checksum="3648CF48EF26F67E" modified="2019-10-16" version="1">MIETTPPSPERFERAREIYRRLTQEIGKLYVGQDELVLGTLTALFSHGHVLIESVPGLGKTLFVRTLGKVLGCQFGRIQFTADLMPSDITGAPVFDMKESEFRFHPGPVFTQLLLADEINRSPAKTHAALLEIMQEYRVTIDGVSHEVPRPFLVMATQNPLESEGTYNLPEAQLDRFMFKLIIDYPDSQQEAEILRMHSLQIDLSQRLHDEVATVTSPQEIREMIALCGTVRIDDSLVDYINNLVRLTRNWPSLHIGASPRAGIALMQSARTLAAFGGRDYATPDDVVEVVLPALRHRVQLTAEAEVEGRRVDEELTALIRSVEVPRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXG0</accession>
    <name>A0A518IXG0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_37850</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="34"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="133" mass="14860" checksum="A6B7376AAD770B62" modified="2019-10-16" version="1">MMGYAVERNIHPIPPRSRAIILQISMNRELTRSIISLALASMLLATATLLISLAIDRTIGLRPGWPAIAEERTPPQGRPMVPPGSYEQTIDQAPIDANLRQLWESLNEEEQKNQLKFPVDVERAMSVQPDHGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXI2</accession>
    <name>A0A518IXI2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_38020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021822624" evidence="1">
        <location>
            <begin position="30"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="140" mass="14920" checksum="330D27A9476177DF" modified="2019-10-16" version="1" precursor="true">MSKTLNSKLAAGTVVLMMLLSGCSGGTDAEGFVQLPGEVTWNGEPVQDGMIIFRGSDPSERNVAAPITDGKFVVKIQPGKKTVEVTARREVAGKFDVGPSGEKVPLIESYIPAKYNSESELTTEIVVPGTDTLQFSLQEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IY16</accession>
    <name>A0A518IY16_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nickel uptake substrate-specific transmembrane region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_39950</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019613">
        <property type="entry name" value="DUF4198"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10670">
        <property type="entry name" value="DUF4198"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022230704" evidence="1">
        <location>
            <begin position="22"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="268" mass="29271" checksum="DC6D4B2B717F7C05" modified="2019-10-16" version="1" precursor="true">MKISSFLAVALVVTLSQIASAHKVWLLPSQTSLSGNDPWVTVDAAVSNDLFYFNHHPLRLDNLVITAPDGGSAEAQNPATGKYRSVFDVQLEQEGTYRIALMNQGFFASWVENGERKRWRGSAASFATEVPTDAENLKVTESVGRIETFVTNGAPSKESLKPTGVGIELVAATHPNDLYAGEKSQFQLLVEGKPAAGLEIEIIRGGTRYRDSQEEIIATTDENGEFTVAFEKPGMYWLSTSSQDEKGKNAQAKTRRLSYAATLEVLPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IY19</accession>
    <name>A0A518IY19_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_39940</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014469">
        <property type="entry name" value="DUF2271"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10029">
        <property type="entry name" value="DUF2271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF014995">
        <property type="entry name" value="UCP014995"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022190877" evidence="1">
        <location>
            <begin position="26"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="177" mass="19728" checksum="98B88A97875C8602" modified="2019-10-16" version="1" precursor="true">MLKRFPLLVASFALALAMPAAPATAAEIELSIEIPRLNVSEYHRPYVAAWIQTADRKQIRNLTVWYQMRDTNEGHGTKWLPDLRQWWRISGRSLDVPVDGVTGATRPVGKHSLTFTDKQPQLADLPAGEYTLIVEASREVGGRELVKIPFTWPATSPQTLDAKGKKELGEVTLSVKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYD3</accession>
    <name>A0A518IYD3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DinB superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_41130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024775">
        <property type="entry name" value="DinB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12867">
        <property type="entry name" value="DinB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DinB_2" evidence="1">
        <location>
            <begin position="8"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="162" mass="17511" checksum="04012EE71874CD85" modified="2019-10-16" version="1">MELEAKLFTMMRGVLTEMVDGISDTDFQSLPAGGGNSPNWILGHLALCNEFGLMTMGLPVERAEQMMPIYGPGSQPTEAADNLMSKADLVTFFNESADRFLMAVANASDEDLAAERSSPILKAHLPTVGDMVGHLLTTHFGMHIGQLSAWRRGRGMGSVLKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYG8</accession>
    <name>A0A518IYG8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_41350</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010985">
        <property type="entry name" value="Ribbon_hlx_hlx"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47598">
        <property type="entry name" value="SSF47598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="169"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="197"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="246" mass="27973" checksum="A9054EB7EAC643D1" modified="2019-10-16" version="1">MVSHENFSNPTQTINNTSNENRFAGNESTPAPATNSRLTLPPMNDGLSLQERPAEAMRLAQEVFTQTSNWIEFFRETLGVEGFVRKLFPTVDEMRYFEESHEHGQIQEMLTALRSQDTGKGDTLEPQRMITVRLPKSLHEFLRVQAEELELSINKLCISKLLQTIDEKMVPEERGGRRGRRPGPQGPRKKKEEEVATQQPAQQPYGSQTPYGNHAPYGSQTPYSSQPLRSPQPNSYQQPPQRPHFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYS7</accession>
    <name>A0A518IYS7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Elongation factor 4</fullName>
            <shortName evidence="5">EF-4</shortName>
            <ecNumber evidence="5">3.6.5.n1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Ribosomal back-translocase LepA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">lepA_2</name>
        <name evidence="5" type="synonym">lepA</name>
        <name evidence="7" type="ORF">Mal33_42580</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>GTP + H2O = GDP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="3.6.5.n1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Peripheral membrane protein</topology>
            <orientation evidence="5">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.n1" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045727">
        <property type="term" value="P:positive regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03709">
        <property type="entry name" value="lepA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00071">
        <property type="entry name" value="LepA"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="EF-4"/>
    </dbReference>
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        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
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        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
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        <property type="entry name" value="LepA_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013842">
        <property type="entry name" value="LepA_CTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035654">
        <property type="entry name" value="LepA_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
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        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06421">
        <property type="entry name" value="LepA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
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        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="SSF54980"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="lepA"/>
        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
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    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="6">
        <location>
            <begin position="1"/>
            <end position="182"/>
        </location>
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    <feature type="binding site" evidence="5">
        <location>
            <begin position="13"/>
            <end position="18"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
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    <feature type="binding site" evidence="5">
        <location>
            <begin position="129"/>
            <end position="132"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00071"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV58240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="597" mass="66504" checksum="C82F076407DEF221" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYW9</accession>
    <name>A0A518IYW9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative metallophosphoesterase YhaO</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">yhaO_2</name>
        <name evidence="2" type="ORF">Mal33_43000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetia</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos" evidence="1">
        <location>
            <begin position="3"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="426" mass="47375" checksum="BED62665F27065AF" modified="2019-10-16" version="1">MVRFIHAADIHLDSPMLQLEHYEGAPADEIRRSTRRALTNLIDLAIEKQVDFVLIAGDLYDGDWPDHNTGLFFTSEVARLRAAEIPLYFISGNHDAANKLTKALPLPTNPDGSPVQLSSTKVDSVLLEDLGVAIHGRGFRKQAETDNLSEKYPRATRDLLNIGMLHTSLQGAQGHAPYAPCTPQQLADKEYDYWALGHIHIREDRAIEGSCPIVFSGNTQGRSVRETGAKGCVLVELDPIAPPKLEFQPLDVCRWEICEIDATEIDRIDDLIQQCKTRMQAICANNPDRTSIVRVRVVGQTPLYSTLQARLEHWQSVMRQETFDIDEGSIWMERLRVKATAPREAITYDASGPIGELLQTIGSVSADPDAMAAIQSALEPLVAKLPIELVEDGDGVAWNHQDQIRQWLDEAEPLLLNRLATLEADV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZH9</accession>
    <name>A0A518IZH9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Inositol 2-dehydrogenase</fullName>
            <ecNumber evidence="3">1.1.1.18</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">iolG_14</name>
        <name evidence="3" type="ORF">Mal33_45230</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.1.18" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050112">
        <property type="term" value="F:inositol 2-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043906">
        <property type="entry name" value="Gfo/Idh/MocA_OxRdtase_bact_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19051">
        <property type="entry name" value="GFO_IDH_MocA_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GFO_IDH_MocA" evidence="1">
        <location>
            <begin position="59"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="GFO_IDH_MocA_C2" evidence="2">
        <location>
            <begin position="172"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="435" mass="47624" checksum="58B54F9E365A437B" modified="2019-10-16" version="1">MTKRSSLNRRRFVQSSGAAAAVLSSGVWSETSAKESTSANNKLKILCVGTANRAAADVEGVKGEDIVGLCDIDKNYLDRAAAQFKSAKLYSDYREMIDKEAANADAIVIGNADHNHAPASLRAINAGLHCYCEKPLTHTVTEARIITEAARAKGVATQLGTQIHAGDNYRRVTEIVKAGILGDVTDVHVWVGKGWGGGERPEGGEQPPASLDWDLWLGPAPERPYVAGRYHPAQWRRWWDFGQGTLGDMACHYMDLPFWALDLKHPTTISAEGPEVHPETCPLGLKVEYQFAKRGDLAPVKLTWYDGNMTPREVAGERVPGSGVMFVGTEGKMFANYGSYKLFPKEKFAGFQPPEQTIPKSIGHHAEWIKACKDGSPTTCNFDYSGALTETVLLGNVAYRTGKELQWDAAALKATDCPEADKYLSKEYRKGWEVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZM7</accession>
    <name>A0A518IZM7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DNA-binding transcriptional regulator CsiR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Mal33_45690</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
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        <property type="protein sequence ID" value="QDV58546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="component" value="Chromosome"/>
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        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="GntR_C"/>
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        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
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        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
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        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
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        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="SSF48008"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="FCD" evidence="5">
        <location>
            <begin position="156"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
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            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV58546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="294" mass="33342" checksum="4AF078796D7C5D1F" modified="2019-10-16" version="1">MSITDFIRNDLALRLRSGRDLPAQLTLDSLAELYNVSFTPVRAAVADLIDEGLLRKGANRRLEACPLANALKEFDQLTEAPKPPADPSEKIADDLVLLSLEGKSVYLREEVTAEKYSLSRSAIRNILHQLAGEGMLDHIPRRGWRLRPFRQDDLQAFIEVREAMELKALQLARPRLDNQQLQAILERNAPPASPTDRFPVDESLHEYLVATSGNGYIRDFFERQGRYFRLLFRWEDNDRSAALETLKQHRDVVQALLDEDWASAEAALSHHIRSNHPVLMTKPPTEAPPPTAPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZN6</accession>
    <name>A0A518IZN6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RNA-splicing ligase RtcB</fullName>
            <ecNumber evidence="4">6.5.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rtcB</name>
        <name evidence="4" type="ORF">Mal33_45810</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="3">Binds 2 manganese ions per subunit.</text>
    </comment>
    <dbReference type="EC" id="6.5.1.-" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008452">
        <property type="term" value="F:RNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001233">
        <property type="entry name" value="RtcB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036025">
        <property type="entry name" value="RtcB-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01139">
        <property type="entry name" value="RtcB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103365">
        <property type="entry name" value="SSF103365"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0464">Manganese</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="GMP-histidine intermediate" evidence="1">
        <location>
            <position position="386"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="142"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="219"/>
            <end position="223"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="220"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="247"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="330"/>
            <end position="331"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="330"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="362"/>
            <end position="365"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="386"/>
            <end position="389"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR601233-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR601233-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR601233-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV58558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="465" mass="50575" checksum="B61ABF3455969A91" modified="2019-10-16" version="1">MKTRELNNLGIPKGIAMQAAVEAVRNASAKGLKRPELRTAIAAIVEDPASAKDDPLWGSLAEALQTVFSAQERYVGRDEPAPWRQWGDGLEAGAVSQMVDACKLPVTVSGALMPDAHLGYGLPIGGVLATKDCVIPYAVGVDIACRMKMTVLDMPVETLDTNQDRLRNAIERETQFGIGASFRKRRQHEVMDADWRVSPITFQNKDKAWKQLGTSGSGNHFVEFGVLTLPVDDLGLAAGTYLALLSHSGSRGTGASVCAHYSSVAKATHPELPRELQNLAWLNLDTQEGQEYWNAMNLMGEYAAANHACIHREIASHLGVEVLLDVENHHNFAWRESHGGEDLIVHRKGATPAGQGVLGIIPGSMGTPGYVVRGKGVEESLLSASHGAGRRMSRTAAKKQFRWKEVKKFLDDRGVTLMSAGLDEVPMAYKDIDQVMASQHDLVETVARFDPRLVKMAEAGERPED</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZV4</accession>
    <name>A0A518IZV4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cobalt-zinc-cadmium resistance protein CzcA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">czcA_6</name>
        <name evidence="3" type="ORF">Mal33_46420</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2090.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82714">
        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="362"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="388"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="419"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="459"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="487"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="524"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="571"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="919"/>
            <end position="938"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="945"/>
            <end position="965"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="971"/>
            <end position="996"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1017"/>
            <end position="1036"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1048"/>
            <end position="1073"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="149"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1096" mass="120210" checksum="8946738CD7F355AA" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J056</accession>
    <name>A0A518J056_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_47440</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="62" mass="6854" checksum="00093B39CE1DDFA6" modified="2019-10-16" version="1">MTVDFLDDNGKSTRPSIALQVHCVCMCGDIAVNHDDIASLVNSQMQIHCKSRLGCLNRHRQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J062</accession>
    <name>A0A518J062_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Molecular chaperone Hsp31 and glyoxalase 3</fullName>
            <ecNumber evidence="2">4.2.1.130</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">hchA</name>
        <name evidence="2" type="ORF">Mal33_47580</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="4.2.1.130" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019172">
        <property type="term" value="F:glyoxalase III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DJ-1_PfpI" evidence="1">
        <location>
            <begin position="66"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="268" mass="29283" checksum="1DAC30427A5134BB" modified="2019-10-16" version="1">MSRNITTGTLLLATFALLISGCKNELGESQTDTEIQKSTAKKVLFVVTSHDEKGDTGEKTGYYLGEVTHPWEVLHSAGYEIDFVSPKGGKAPVDAFDMSDPINKKFWDDDLYRNKVENTKTPSEVNPDDYVAIHYAGGHGAMWDFAGNNAIAEIAAKIYENNGVVSAVCHGPAGLVNIKLSDGTYLVDGKKVNAFTNEEEVKVELDEVVPFLLEDKLIERGAQFEKSEPFQEHVAVDQRLVTGQNPQSATGVGMATLKELQKLNEASQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0G3</accession>
    <name>A0A518J0G3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Transcriptional regulatory protein ZraR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">zraR_12</name>
        <name evidence="9" type="ORF">Mal33_48580</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00060">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002197">
        <property type="entry name" value="HTH_Fis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002078">
        <property type="entry name" value="Sigma_54_int"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025662">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025943">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025944">
        <property type="entry name" value="Sigma_54_int_dom_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02954">
        <property type="entry name" value="HTH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00158">
        <property type="entry name" value="Sigma54_activat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01590">
        <property type="entry name" value="HTHFIS"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SSF49879"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00675">
        <property type="entry name" value="SIGMA54_INTERACT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00676">
        <property type="entry name" value="SIGMA54_INTERACT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00688">
        <property type="entry name" value="SIGMA54_INTERACT_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50045">
        <property type="entry name" value="SIGMA54_INTERACT_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="FHA" evidence="7">
        <location>
            <begin position="42"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma-54 factor interaction" evidence="8">
        <location>
            <begin position="367"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="340"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV58833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="683" mass="75147" checksum="52150A0A18AB25DD" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0G6</accession>
    <name>A0A518J0G6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptide deformylase</fullName>
            <shortName evidence="2">PDF</shortName>
            <ecNumber evidence="2">3.5.1.88</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Polypeptide deformylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2 3" type="primary">def</name>
        <name evidence="3" type="ORF">Mal33_48620</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>H2O + N-terminal N-formyl-L-methionyl-[peptide] = formate + N-terminal L-methionyl-[peptide]</text>
            <dbReference type="Rhea" id="RHEA:24420"/>
            <dbReference type="Rhea" id="RHEA-COMP:10639"/>
            <dbReference type="Rhea" id="RHEA-COMP:10640"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:49298"/>
            <dbReference type="ChEBI" id="CHEBI:64731"/>
            <dbReference type="EC" id="3.5.1.88"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="2">Binds 1 Fe(2+) ion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the polypeptide deformylase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.88" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042586">
        <property type="term" value="F:peptide deformylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00487">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.45.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00163">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023635">
        <property type="entry name" value="Peptide_deformylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036821">
        <property type="entry name" value="Peptide_deformylase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10458">
        <property type="entry name" value="PTHR10458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01327">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004749">
        <property type="entry name" value="Pep_def"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01576">
        <property type="entry name" value="PDEFORMYLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56420">
        <property type="entry name" value="SSF56420"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00079">
        <property type="entry name" value="pept_deformyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="2">
        <location>
            <position position="135"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="138"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="194" mass="22178" checksum="0344E41872EF4F10" modified="2019-10-16" version="1">MPLEIVPYPHPTLRYKSKPIRKVDKALREVVAEMFDLMYESRGVGLAANQVDIPLRMFVVNPSGTRGDGEELVLINPVIQRPKGSWQAEEGCLSLPGIYGNVTRPKEIRLSAFDLKGNPIERTIDDFLGRVLQHENDHLDGVMFIDRMTDEARRDLEGALAEFEIDRESCQQTGSIEPDDVIIERRNEWEQRYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0N3</accession>
    <name>A0A518J0N3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acetylxylan esterase</fullName>
            <ecNumber evidence="4">3.1.1.72</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">axeA1_1</name>
        <name evidence="4" type="ORF">Mal33_49170</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.1.72" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046555">
        <property type="term" value="F:acetylxylan esterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002925">
        <property type="entry name" value="Dienelactn_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01738">
        <property type="entry name" value="DLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021722171" evidence="1">
        <location>
            <begin position="24"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="domain" description="Abhydrolase_3" evidence="3">
        <location>
            <begin position="60"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="DLH" evidence="2">
        <location>
            <begin position="206"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV58892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="289" mass="31197" checksum="CBEE173FC2A1B363" modified="2019-10-16" version="1" precursor="true">MPSRIQISTFVSLIVFASALAAAAEPEAPSHVYKTVDGRKLKLYVTEPTGDSAGQLRPAIVFFHGGGWVGGAPGQFTSHSQYFASRGVVCFQVQYRLLDRKSKTPPIVCIEDAKSAMRWIRARSKQFGIDPNRIASAGGSAGGHLAAFVGCVDSGDATSDDLSVSAKSQAMLLFNPVYDNGPGGWGTARVRDRYKHFSPAHNLSKDDPPSIVFLGSNDRLIPVATAEKFRDASKAVGVDSELHVYADQGHGFFNVGNDDGRWYRLTVIAADRFLNKLGWIDGPPTLKQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0P8</accession>
    <name>A0A518J0P8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_49270</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021866596" evidence="1">
        <location>
            <begin position="21"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="446" mass="48392" checksum="81405963BED6B85B" modified="2019-10-16" version="1" precursor="true">MKSLAALIVVLAAMETAAFAQNAPYDNPPAVEAPYYRVRYEASSQPGKLIYPVAYTVWVPPAVDTLRGVIVHQHGCGEGSCKSGQTGAFDLHWQALAQKHQCALLSPAYEQPAGTDCQMWCDPRNGSDQAFQKALVDLGKRSGHPELAEVPWALWGHSGGGHWAGGMLMLHPERVAAAWLRSGVPLFEAVEGRNIQPHTLPDAALAVPTMCNFGTKEGYTDKESRFKGVWPSNETFFKSMRGRGALLGIAIDPLTSHECGNSRYLAIPWLDACLSERLPEKSGQAIRPMPQQTAMLTPLPVDEAAFTAAVPAGDFEGDLATSIWLPNPEIAIAWKQFVTDSNVADVTPPPAPTNVHLDGDQLTWQADADLESGIAHFIIERDGKTVATVPEKPKNPFGRPLFQGLQYSDTPAVPLATMRWTVEKAEPGQENPYRVRTVNTAGLVSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0R2</accession>
    <name>A0A518J0R2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Planctomycete cytochrome C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_49540</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011429">
        <property type="entry name" value="Cyt_c_Planctomycete-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011444">
        <property type="entry name" value="DUF1549"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022655">
        <property type="entry name" value="DUF1553"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07635">
        <property type="entry name" value="PSCyt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07583">
        <property type="entry name" value="PSCyt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07587">
        <property type="entry name" value="PSD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PSCyt1" evidence="4">
        <location>
            <begin position="56"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="PSCyt2" evidence="2">
        <location>
            <begin position="161"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="domain" description="PSD1" evidence="3">
        <location>
            <begin position="702"/>
            <end position="958"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="384"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV58929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1014" mass="113343" checksum="5325826661355203" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0S9</accession>
    <name>A0A518J0S9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_49780</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="86" mass="9605" checksum="3E55F1239E443E92" modified="2019-10-16" version="1">MSIDKPLANQSRHSKTVRHRQRPGVFNLLLYQAAHHSMTNGTANLLCDNELATATLKMALRHGRKSAKKCFNADLADFSELRCEPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0W9</accession>
    <name>A0A518J0W9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Fructose-1,6-bisphosphate aldolase</fullName>
            <shortName evidence="8">FBP aldolase</shortName>
            <ecNumber evidence="8">4.1.2.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">fbaA</name>
        <name evidence="9" type="ORF">Mal33_50160</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 8">Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate</text>
            <dbReference type="Rhea" id="RHEA:14729"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="4.1.2.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="8">One is catalytic and the other provides a structural contribution.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 8">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 4/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 8">Belongs to the class II fructose-bisphosphate aldolase family.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.13" evidence="8"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00183"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004332">
        <property type="term" value="F:fructose-bisphosphate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00947">
        <property type="entry name" value="TBP_aldolase_IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000771">
        <property type="entry name" value="FBA_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006412">
        <property type="entry name" value="Fruct_bisP_Calv"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01116">
        <property type="entry name" value="F_bP_aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001359">
        <property type="entry name" value="F_bP_aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00167">
        <property type="entry name" value="cbbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01521">
        <property type="entry name" value="FruBisAldo_II_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00602">
        <property type="entry name" value="ALDOLASE_CLASS_II_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00806">
        <property type="entry name" value="ALDOLASE_CLASS_II_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="8 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="7 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Dihydroxyacetone phosphate binding" evidence="6">
        <location>
            <begin position="233"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Dihydroxyacetone phosphate binding" evidence="6">
        <location>
            <begin position="275"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="83"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="142"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>dihydroxyacetone phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001359-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001359-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR001359-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU365019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV58991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="336" mass="36458" checksum="3DAEBB59464C6141" modified="2019-10-16" version="1">MPLVPLRVVLDHAAENNYGVAAFNVNNMEQIQSIMEAANETDSPVIVQASRGARAYSQDAYLRHLMLAATELYPHLPIVMHQDHGNSVETCMSAIENGFTSVMMDGSLEEDGKTPASYDYNVKVTAEVVKQAHAKGVSVEGELGCLGSLESGEGEQEDGHGAVGELTHDQLLTDPEEAERFVAETNVDALAVAIGTSHGAYKFSRKPDGEVLAMSRIEEIHRRLPNTHLVMHGSSSVPQELQDIINAFGGKMKQTYGVPVEEIQRGIKSGVRKINVDTDNRMAITGAIRKVLQEDPSAFDPRAYLKPSREAMKQVCVDRMVAFGQAGNGSKLGKTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0X1</accession>
    <name>A0A518J0X1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Outer membrane biogenesis protein BamB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_50090</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002372">
        <property type="entry name" value="PQQ_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13360">
        <property type="entry name" value="PQQ_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="442" mass="47500" checksum="EEEEF3D9A79712B3" modified="2019-10-16" version="1">MFWFLTILVAMANGEPAVWPAFLGAGARPGATQSLPLEWTATENIAWRATLPGHGQSSPVVWGERVFVTGVEGPNKETYHTVCIDLKSGEELWRQSIENSAPVANSYYVSRAAPTPVVDQDRVIAFFESGDCVAYSHAGDMLWKRSLVDELGDVEAEFGIGASPCQTATTMFVLIEHDGPSGLLAIDKATGKTEWKVDRESRRSWSSPGVIHVDGATQIVVSSAGSVDGYNPESGDVLWSFTDVGGNTGTSPIDYGNGRVLIGASPGRNGENAGSAADSNCLLQIARQGDGWTVKREWIAEGAVPSWASPIVHQGLAYWINRAGVVHCFDAQTGESVYSKRTKQSCWATPIGVGDRIYLFGQHGIVSVLAAGRKFEVLAENESWNDETLPAEPLLAEEESPERRRGVAMFSKPTLYGAAVVEDSIVLRVGNCLICVRPSDPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J145</accession>
    <name>A0A518J145_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycogen synthase</fullName>
            <ecNumber evidence="2">2.4.1.11</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_50960</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.4.1.11" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004373">
        <property type="term" value="F:glycogen (starch) synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="257"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="438" mass="47080" checksum="5B80FBE666727BD3" modified="2019-10-16" version="1">MPYANWNTMSKTSGIPYRNLILVVRADPTICGHSTEARNLAEAARAAGIENVHIVSYPLDVLAESGLPLKPLDSVAPYSPGIFVDRPEPVGDYKVLDGRLGYAIAGHLIDLVNRLPGRTAIMNLYLVPHGQMVMQSVETLRGMGTREAPATIAEAVGSDVTNVVANALSTGQLGAAAIVLQNYLAHDLPVAVSEYTRKLIIEAGQQVDERLKTTFAYQLELRVRISYPAIDTSVYLSVAEQAEQNASVLAGRGLSPDGFLLFLSRLSKAKGVDDLIRAYRASKLYGKKVLAICGTGPDADRLIELAAGDPNIRFFDDVGDEEKLALMHNCYAYCLPSKPRPEFTETFGIAIAEAMLSGGLGPVITTRTGGIPEATGDHCLYHAAGDVADLTSKLDLVASMSDWDRGGLSRAAQQYARRFDRAVILDRLLSAPAIRAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J155</accession>
    <name>A0A518J155_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Molybdopterin biosynthesis protein MoeB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_50990</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="1">
        <location>
            <begin position="4"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="115" mass="12920" checksum="2F43F5BDB70CB955" modified="2019-10-16" version="1">MNSSQTPPVLVDVRSDAERVVSRIPGAITQQEFEASSDDKFAGRRVVTYCTVGGRSYWYARKLAARGIEAANYRDSILGWCRASLPLESPDGQATNAVHPYWRIFHVPDRYDVKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1B6</accession>
    <name>A0A518J1B6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">O-acetyltransferase OatA</fullName>
            <ecNumber evidence="3">2.3.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">oatA</name>
        <name evidence="3" type="ORF">Mal33_51430</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.3.1.-" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002656">
        <property type="entry name" value="Acyl_transf_3_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01757">
        <property type="entry name" value="Acyl_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="173"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="219"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="250"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="275"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="315"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="351"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl_transf_3" evidence="2">
        <location>
            <begin position="27"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV59117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="412" mass="45838" checksum="72E5196227E4D159" modified="2019-10-16" version="1">MASHAPQTDICPAVGLDRVWRVGKHVAELDGLRGFAILIVTLYRFSKEIPTDSVLGHLMHLGASFGSRGVELFFVLSGFLITGILIDAKDQPHYFRNFIARRSLRIFPLYFATLIALVVAGHLIPAMRSMFHDAIDNQFYLWTYLVNVKMSLADQWCFGYLDHFWSLAVEEHFYLVWPFVLYLISSKVALRTAVVLAIVSAAARIAFVLLTDNGVAPDVLTLFRCDALLIGAAIALIARQPRGLDPLKRWLPITTMLGGLFVVACGVTGKRFFTIPLTIWPIVWGGILIWLLTANRSAPLARFFNLKFLRTLGKYSYAMYVFQNPLIPLTSAVVSVAAFETLVGGPLLANVLYIGVMFILTYAAAVLSWNVLERHCLQLKRWFPTDGSEDAAARRNNKSTAGVFVPTNVPAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1E8</accession>
    <name>A0A518J1E8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nitrite reductase (cytochrome; ammonia-forming)</fullName>
            <ecNumber evidence="2">1.7.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Mal33_51940</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>6 Fe(III)-[cytochrome c] + 2 H2O + NH4(+) = 6 Fe(II)-[cytochrome c] + 8 H(+) + nitrite</text>
            <dbReference type="Rhea" id="RHEA:13089"/>
            <dbReference type="Rhea" id="RHEA-COMP:10350"/>
            <dbReference type="Rhea" id="RHEA-COMP:14399"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16301"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="EC" id="1.7.2.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome c-552 family.</text>
    </comment>
    <dbReference type="EC" id="1.7.2.2" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042279">
        <property type="term" value="F:nitrite reductase (cytochrome, ammonia-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023155">
        <property type="entry name" value="Cyt_c-552/4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003321">
        <property type="entry name" value="Cyt_c552"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036280">
        <property type="entry name" value="Multihaem_cyt_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02335">
        <property type="entry name" value="Cytochrom_C552"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13435">
        <property type="entry name" value="Cytochrome_C554"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48695">
        <property type="entry name" value="SSF48695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0106">Calcium</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="9" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="Cytochrome_C554" evidence="10">
        <location>
            <begin position="175"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="9">
        <location>
            <begin position="626"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="9">
        <location>
            <begin position="713"/>
            <end position="746"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00029373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QDV59166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="791" mass="88361" checksum="D27A50638C16E5FF" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1G6</accession>
    <name>A0A518J1G6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA gyrase inhibitor YacG</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1 3" type="primary">yacG</name>
        <name evidence="3" type="ORF">Mal33_52070</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1">Binds 1 zinc ion.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Interacts with GyrB.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA gyrase inhibitor YacG family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008657">
        <property type="term" value="F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00649">
        <property type="entry name" value="DNA_gyrase_inhibitor_YacG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005584">
        <property type="entry name" value="DNA_gyrase_inhibitor_YacG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36150">
        <property type="entry name" value="PTHR36150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03884">
        <property type="entry name" value="YacG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="45"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="11"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="14"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="29"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="33"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV59179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="65" mass="7537" checksum="3DEC93F5C96BECBD" modified="2019-10-16" version="1">MTPETPQWVSCPTCQTRFVMDETETPPFCCERCQLVDLGRWLDEEHGLPHEGDPGDVPVEYRNEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1I1</accession>
    <name>A0A518J1I1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">GDP-mannose 4,6-dehydratase</fullName>
            <ecNumber evidence="3 4">4.2.1.47</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">GDP-D-mannose dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">gmd_2</name>
        <name evidence="4" type="synonym">gmd</name>
        <name evidence="6" type="ORF">Mal33_52200</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>GDP-alpha-D-mannose = GDP-4-dehydro-alpha-D-rhamnose + H2O</text>
            <dbReference type="Rhea" id="RHEA:23820"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57527"/>
            <dbReference type="ChEBI" id="CHEBI:57964"/>
            <dbReference type="EC" id="4.2.1.47"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 4">
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.47" evidence="3 4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008446">
        <property type="term" value="F:GDP-mannose 4,6-dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070401">
        <property type="term" value="F:NADP+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019673">
        <property type="term" value="P:GDP-mannose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00955">
        <property type="entry name" value="GDP_Man_dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006368">
        <property type="entry name" value="GDP_Man_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43715">
        <property type="entry name" value="PTHR43715"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="5">
        <location>
            <begin position="5"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV59192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="325" mass="36502" checksum="5E4CCFE6495000E2" modified="2019-10-16" version="1">MRKALITGISGQDGSYLTELLLAKGYEVHGLVRRTSSTVRTRLEHLFSDPSIYNETLFLHYADIDDATTIRRLLMRIQPQEVYHLAGQSHVGASFEIPESTCEFTAMGTLRLLEVLRDLPERPRMMQISSSEIFGRPAVAPQNESTPLNPVSPYGVAKAFATHMIRVYRDSFGFFACNAICFNHESPRRGESFVTRKISLAAARIKLGLQKSLTLGNLDAQRDWGYAPEYVDAFWRILQHDTPDDYVIATGQSHTLGDFLDAAFGAVDLNWQDYVRTDPKYMRPAESHQLVGNPAHAIKTLDWHPHTKAPELAALMVEHDMAALS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1K6</accession>
    <name>A0A518J1K6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_52460</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="146"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="174" mass="18153" checksum="4D7E5A709C7919FA" modified="2019-10-16" version="1">MDLTKRALHFLLIGTVVSWHMPIATLAAQQPPQAIAAAPEMTSIPVLLVADRTLQGTSITRDGKPASGGTVVLGQKGKVLAKTTADESGRFQFTIEKPGDYQIASTDAAAFVSCFPAATAPKYAVKQILISQDAMIARGQQPVSALLHPLLIGLVIAAAIVIPIAVSNNKDDAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1S6</accession>
    <name>A0A518J1S6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATP-grasp domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_53170</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003806">
        <property type="entry name" value="ATP-grasp_PylC-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02655">
        <property type="entry name" value="ATP-grasp_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="2">
        <location>
            <begin position="200"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV59289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="361" mass="39636" checksum="1870F0EB4E39195F" modified="2019-10-16" version="1">MGATARAAAQSARRSGLRVAAIDLFGDRDLREACDRWSPLRSDRSLAEQLAGASVDAVVPLGGLESRLLELDALRKTHRLFGATAQQIRQLNDPAWLDRAAEVADLARPPRCTHKPSPTSGWLFKRAFSTGGLGVFPASQMPAVFDSDDWFERQILGRSFGVNFLASRDGVDLIGVAASLRSRQRPKPFQYEGSIGLPMLPDSLQQRVQRLAEYIVQETQLRGLFGIDVIVDPAKRIWLLELNPRWTASMELFDRGSTSLLQRHIAACKEEEVAAIEKSKTLIGKRVLYTDHAIRFAYQPLRDALPDAIEIADIPADSSEILAGAPICTLIASGPSPREIANRLAVARQISQLILEPLGSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1V7</accession>
    <name>A0A518J1V7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_53500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="350" mass="40128" checksum="66790FA03EC20BB1" modified="2019-10-16" version="1">MKILVLNANFDEYALGWSYKRAFESLGHDVSMINPGERLAEFRLWNNRYSRRLLERPLLQAFNKRWLPELLDRPADVIWVGKGAWALPQFWRAFKEARPNTKLVCFNGDDPLTTFSRGGNRTWITESISCYDLFCTYKSSLVEPLLQAGAKQVECVPFGWDPSIHPMQPYGNFQYDLLFIGNGDEHRSKWLTEILSNPVARNWKTAIFGYWPKKLSKPFSKSVHNRQLVSQKMAQTVAASKVTLNILRIQNEGSHNMRTFETPGCGGLLATQFSEEQHFFLGGGHNEEQGAIFFDNANDAAVKLSHAIHEDDFRQTIINASRKKIQQHTYKQRAKQTLDAIWSASDHNGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J257</accession>
    <name>A0A518J257_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Carboxylesterase NlhH</fullName>
            <ecNumber evidence="3">3.1.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">nlhH_4</name>
        <name evidence="3" type="ORF">Mal33_54570</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.1.1" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080030">
        <property type="term" value="F:methyl indole-3-acetate esterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022167206" evidence="1">
        <location>
            <begin position="23"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="domain" description="Abhydrolase_3" evidence="2">
        <location>
            <begin position="67"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV59422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="302" mass="32717" checksum="E498D0497C4EA82E" modified="2019-10-16" version="1" precursor="true">MNIHQLTSAVLLGVLAINAVAAAEDSQDREPAEYSVRFDLAYKTEGDQSLLADVYQPAGVVDSCPIVLVVHGGAWMSGDKALPATYARMFAQHGIAAVSINYRLAPAHKFPAQLDDVRAALAWVHDHAEENRWDLNRLGLFGYSAGAHLSCMIAMLDDEPAETVAKTTQLSADDLCWGKLPRPLAVVAGGTPADFRDLPLDNSLLAYFFGGTRRERPEAYEFGSPAVLVSGGDPPTLFYHGTRDLLVPIAGAESLFQRQQKLKIDSEFVRVEGLGHLLSFMDAGARANVLRFMKSHLSPAAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J272</accession>
    <name>A0A518J272_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Arylsulfatase</fullName>
            <ecNumber evidence="5">3.1.6.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">atsA_39</name>
        <name evidence="5" type="ORF">Mal33_54670</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="PTM">
        <text evidence="1">The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.</text>
    </comment>
    <dbReference type="EC" id="3.1.6.1" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004065">
        <property type="term" value="F:arylsulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022111408" evidence="3">
        <location>
            <begin position="23"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase" evidence="4">
        <location>
            <begin position="25"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="305"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="modified residue" description="3-oxoalanine (Cys)" evidence="1">
        <location>
            <position position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR600917-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV59432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="482" mass="53035" checksum="57B99B7A27D38B76" modified="2019-10-16" version="1" precursor="true">MRTSYRIVAIALALLASSIAQAAKPNIVFILVDDLGYGDLGCYGQQVIQTPRLDQMAAEGMRFTNFYAGNTVCAPSRSVLMTGQHMGHTHVRGNAGGPDMAIQSLRDEDITVAEVLKSAGYATGLCGKWGLGDDAPGGRSGLPRRQGFDYFYGYLNQVHAHNYYPEFLWRNEERVELGNVVQSTGRLHGGFMGGWATKKVAYSHDLIADEALGFIKSNASTGENRKPFFLYLSLTIPHANNEAARGIGDGQEVPDYGIYADKDWPNPDKGQAAMITRMDADVGRLLDLLEQLDIDDETIVLFSSDNGPHAEGGQDPERFDPNGPLRGMKRDLTEGGIRVPLIVRWPGTTPPGSTSDHVGYFGDVMATAAELSGVQTPEGTDSISFVPTLTGHPELQQQHEYLYWEFYERGGKQAVRAKNWKAIRKPWMTGKTQLYDLSTDIGETNDVADANPDVVKQLEAMMTEAHVEHPNWTVRRRVPAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J289</accession>
    <name>A0A518J289_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_54900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="54" mass="6374" checksum="051FF2D8D805B42A" modified="2019-10-16" version="1">MKDACPIRLVSFKVQDTYPVESRPMQTLHKTIILVPIYARGVWQRPYLDRSLNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J2A4</accession>
    <name>A0A518J2A4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">2-keto-3-deoxy-L-rhamnonate aldolase</fullName>
            <ecNumber evidence="2">4.1.2.53</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rhmA_2</name>
        <name evidence="2" type="ORF">Mal33_55010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="4.1.2.53" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106099">
        <property type="term" value="F:2-keto-3-deoxy-L-rhamnonate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005000">
        <property type="entry name" value="Aldolase/citrate-lyase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03328">
        <property type="entry name" value="HpcH_HpaI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HpcH_HpaI" evidence="1">
        <location>
            <begin position="28"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="253" mass="28070" checksum="238D42B47BE4953E" modified="2019-10-16" version="1">MRKSKTLAKIRQGEVIRTCVIGHYIPAYVCHAARAGYDCIWVDLEHRAMTKREVEALLAFSHLYDIDIMMRPPTLEKTGLYRYLEDGAAGLLIPHVSTAERAKMLVDAVKFPPLGDRGIDNAGLDADFHIHDADEYVAWANRETFLCVQIETPEGVHNVEEIAAVEGVDMIFVGPGDLGLRLRQSGEMTLDEAWEIVAAACRKHGKAFGGPTLATSEMQKRKDLGAQLLVNSSEFQGWSAALSQDGRRFEDLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J2F8</accession>
    <name>A0A518J2F8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_55570</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="102" mass="11314" checksum="AE9009483E8C43E6" modified="2019-10-16" version="1">MLEDSGQLRTWAIPRIPSPGESVQGLGLPPHRIAYLDLEGEISGGRGSVRRIDRGTYTIIESSDEQLSIEIRGDQLTGQLRFHATESDQLWEISRVDALANL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IM14</accession>
    <name>A0A518IM14_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glucose-6-phosphate isomerase B</fullName>
            <ecNumber evidence="1">5.3.1.9</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">pgiB</name>
        <name evidence="1" type="ORF">Mal33_00840</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="5.3.1.9" evidence="1"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004347">
        <property type="term" value="F:glucose-6-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001672">
        <property type="entry name" value="G6P_Isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11469">
        <property type="entry name" value="PTHR11469"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00342">
        <property type="entry name" value="PGI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51463">
        <property type="entry name" value="P_GLUCOSE_ISOMERASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="429" mass="46960" checksum="B364B1DE0F67894F" modified="2019-10-16" version="1">MGLIQFDFSGAVDADYGVTEAQIADLAPKLLDLRQQIVDVAPPFASLPRELLDGYTELRDDSPLGQIFRVANRLHDEVDAVVVLAGGGAYRGTQALRDACCDPYHNELSRGGRGSKPRMYFTGNDLDNDASSALLHRLGRDLTAIDPVVRRWAMVVIDPAGETRERALALRQFLPAMEESLAADVAQWLPELLLPVTDQPSKLRDLAQAIGCKEIFPIPAAIDERFNVLSAAGVLPAAMLGLDCVQLLEGAAAMDEHFKTAPPETNLVLQYVAIHHLLQTQRGIDRRVMNVWGSALETFGLWHDQLLADSGNQMLPLTTVSPRDGHHLDPANLQGKVVNHLIVHQHRADPWQVGQSDGDHDGLNALSDRKLPDLMTEAIADTDAAMHAAGCPTTQLRMREIDTHTLGQLFQMLMLATTVESQLQRDASI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IM76</accession>
    <name>A0A518IM76_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_01200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="158"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="248"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="343"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="894" mass="94671" checksum="96D59B137788EF43" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IME2</accession>
    <name>A0A518IME2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Ferrous-iron efflux pump FieF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">fieF</name>
        <name evidence="8" type="ORF">Mal33_02080</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1510.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002524">
        <property type="entry name" value="Cation_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027470">
        <property type="entry name" value="Cation_efflux_CTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036837">
        <property type="entry name" value="Cation_efflux_CTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027469">
        <property type="entry name" value="Cation_efflux_TMD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01545">
        <property type="entry name" value="Cation_efflux"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16916">
        <property type="entry name" value="ZT_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160240">
        <property type="entry name" value="SSF160240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161111">
        <property type="entry name" value="SSF161111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01297">
        <property type="entry name" value="CDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="121"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="193"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="219"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="domain" description="ZT_dimer" evidence="7">
        <location>
            <begin position="253"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF16916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV54258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="331" mass="36139" checksum="9A38471978DFE743" modified="2019-10-16" version="1">MQTRRRCAPWIGIKQPFSPRVGLRQNIPLKRQARPEASIIQREGVYREASRTASLGLGVNVFLVILKLVGGTITGSAALIADAINSVGDVASSLAVHGALWMAQQDEDDDHPYGHTKAESIGALSIAILIAFSAGMLAIENIRHLRQVVSVPPQTAAIIAALCAVLKEAIYWQTRRVSSRIDSRSLQAAAWDHRSDAICSAAIAVALFAAPYLGPLGRFADPVAAILVCALLIGIGVRLFWQTALELMDQQADPELTDSIRHRAEEIGEVTRIEKLRVRKSGLEFFVDIHVEVDAQLTVGEGHRIGHLVKDELLRSFPRVRDVLVHVEPDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMI4</accession>
    <name>A0A518IMI4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_02510</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="54" mass="6100" checksum="9AFE12341356D180" modified="2019-10-16" version="1">MCRAVPTRLQRLAHSSLADDTKSSPFLSAPLSRCWYRHTQLVYINISIDAKLPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMI5</accession>
    <name>A0A518IMI5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">4-sulfomuconolactone hydrolase</fullName>
            <ecNumber evidence="2">3.1.1.92</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_02470</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.1.92" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102998">
        <property type="term" value="F:4-sulfomuconolactone hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018732">
        <property type="term" value="F:sulfolactone hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04909">
        <property type="entry name" value="Amidohydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="1">
        <location>
            <begin position="57"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="329" mass="36509" checksum="D69A05D3ACA5C5FF" modified="2019-10-16" version="1">MRNNGSTTSATMAVDDKVFSAVRLSRRHLIGAAAATTALAATNRLAIAADGKSDGYIDAHVHVWTPDTNKYPLDKAYDKSSMQPASFTPEQLMAHAKPAGVNRIVLIQMSFYGVDNSYMLDVMAAHPGRFSGVAVIDPADKPRQTMRQLKSQGVRGFRIVAGKQPADQWLDNPTMHKMWSIAADEGLAICPLMNPEYLPAVDAMCAKYPKTRVVVDHFARIGVDGKIQDAQVEALCRLARHENAYLKASAFYALGKKQAPYTDLGPMIHRCMDAYGSQRMMWASDCPYQVEDGHTYQESIDLIREKLDFLSDQDRAWMLGKTAEKVFWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMY5</accession>
    <name>A0A518IMY5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_04030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011453">
        <property type="entry name" value="DUF1559"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07596">
        <property type="entry name" value="SBP_bac_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="311" mass="33687" checksum="DA83BBE448D78933" modified="2019-10-16" version="1">MRHSQKAKAFTLVELLVVIAIIGILVGLLLPAVQAAREAARRMQCSNNLKQLGLAMHNYHDVYLKFPTGGLPVTLYRIGWPGRIFDFIEEGNRLDAMNSMSADALVTITPYRTLGAPHNGAHEIFANPIPAFACPSSPLGEQARSAPQINVQQGTLHYRANAGSANYGMVAGSDSGKTISTSGVIYPLSKTKFAHITDGTSSTLLIGEISDRQGWTDGMLNGWGGIQPWTWGYYYYGATSGWLQIDNKYVQYPINFPGSVTTNASPYRSAHPGGAQFSFSDGSTRFQSETMDLNILHALATRAQGEVISTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IN63</accession>
    <name>A0A518IN63_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_04760</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="379" mass="43158" checksum="24EAFB33C9F9B5C2" modified="2019-10-16" version="1">MAKEQTGTGFSLKDHLFNRDRVEYLAGLLHAADDRFDASGFVRDTMRSLKSLELKQRITHIAEMLEQHLASDYRAAVKHLVDALPPPLDPTKTDDDFGDFIFAPLGEFVVRNGTAKKYLPLSLKTLKQLTQRFSMEDAIRTFINEHPEATMAELAKWSTDRNYHVRRLVSEGTRPKLPWSKRLTIDLLEPLPLLDTLHADPTRYVTRSVANHLNDIAKSHPDQVLQRLHSWAGQGAQYPAELDWMNRHALRTLVKQGDVDALQFLGFHAKPKIKVSQFELASDEIRPGEAVEFSFVITAEREESLLVDFVIDFVKANGKLSPKVHKLKQLQLRKGESTTLRKRHVLRANATTYTLYPGTHHLTLQINGKPFGTQTFEIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INH6</accession>
    <name>A0A518INH6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_05920</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="135"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="522" mass="57311" checksum="6441D0A339B42CE4" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INP2</accession>
    <name>A0A518INP2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lon protease 2</fullName>
            <ecNumber evidence="3">3.4.21.53</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">lon2</name>
        <name evidence="3" type="ORF">Mal33_06380</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.4.21.53" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003111">
        <property type="entry name" value="Lon_prtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046336">
        <property type="entry name" value="Lon_prtase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02190">
        <property type="entry name" value="LON_substr_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00464">
        <property type="entry name" value="LON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="SSF88697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51787">
        <property type="entry name" value="LON_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lon N-terminal" evidence="2">
        <location>
            <begin position="18"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="214"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="239" mass="26576" checksum="56A42B1E36C3FCC2" modified="2019-10-16" version="1">MSDIESLTRLPDHFDGTVRLFPLPGVVSFPHVMQPLHIFEPRYCDLLTDTLAADRLIAMATLASGWEPDYEGRPALEEFACIGRIVSHTPTDDERHNILLLGIRRVRILQEVVTNQTYRMAKVEVLDDVYSPQAAADRPLLKRLLLEEFRKYIPESALAQENFSQLLDSQMPLGIVSDIIAYTVGIPVAQKLQLLAELDVDQRAKKLIAALAPSQSKGEVCGPENASLSSGFPPPFSQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP19</accession>
    <name>A0A518IP19_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">High-affinity zinc uptake system ATP-binding protein ZnuC</fullName>
            <ecNumber evidence="5">3.6.3.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">znuC</name>
        <name evidence="5" type="ORF">Mal33_07770</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.6.3.-" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="15"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="47"/>
            <end position="54"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV54812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="262" mass="29239" checksum="08659FF6B640177F" modified="2019-10-16" version="1">MNQPLESTANDQIPLSIYDLTVAYHRKPVIWDICVDFPKGQLIGVVGPNGAGKSTLIKAAMDLVPRASGRVLVFGKPYDKNRHRVAYVPQRESVDWDFPVDALDVVTMGLYGQIGWCLPVRRKHRQAALEALDRVGIADLAKRQISQLSGGQQQRTFLARALVQDADLYLMDEPFAAVDASTERAILNILQEMRARGKTVLVIHHDLQTVADYFDYVVLLNMRVVAHGPTTTTFTEQNLTKAYGGRLTLLDEASEAIRRVQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP59</accession>
    <name>A0A518IP59_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_08460</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="121" mass="13829" checksum="C29162E5A8E4F51D" modified="2019-10-16" version="1">MARCDEGYLCEVCGEDVGNISDSDLYLRFVIGELDPERLHTTPERHIRCNPAVGQFIVHPDFEPLVCEGAFSKQELDPEYVQQRETLVSRGFERLREIEAEGPEGDITSYPLPEAIAKYRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPA1</accession>
    <name>A0A518IPA1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cobalt-zinc-cadmium resistance protein CzcB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">czcB_1</name>
        <name evidence="4" type="ORF">Mal33_08590</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="domain" description="HlyD_D23" evidence="3">
        <location>
            <begin position="86"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="HlyD_D23" evidence="3">
        <location>
            <begin position="278"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV54894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="498" mass="54042" checksum="51E14057B0BE86CE" modified="2019-10-16" version="1">MSNPATQPPTEPSRFQPLAKGGPIVFVIALMGLGWFAVHQINAGGSESDQQEAATDDVAAADTLTLPEGKLKAAGFETVPAQSRSLQNYHTIPGRIGYDETKHIEVKAPLDAIVTELRVTPGQAVQGGQLLAVLRSPEIGQARAEILKRRAQQQIAQQVLERETTVAKNLLRLSSMLDQDRSVDAIDDSLADLALGSYRQEIMTAYANLQLSAELLDNIAPLANSGAVTGRAIRERRAERQLAEAAFRTARDQATFAAEQARLNAEADLAEADRQLSLAYQAVETLLGYKQDPQSVALDNESSLSRLEVRAPFAGTIESRSFANNERVSRGDSLVVLANTDTLYVSANIRESDWSAVGIQPGTIVSVTVPALDDRRFEARIHYVGRQVQTDTNSVPLIATIDNREGLLRPGMFVRVTVPIGEARQTLSVKPESVVQHENQEFVFVDMNGGTFQRVNVSTGQAVEDWVEVTEGLSDGQLIVTHGAFLLKSELLLQGEAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPI7</accession>
    <name>A0A518IPI7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Biopolymer transport protein ExbD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">exbD_2</name>
        <name evidence="7" type="ORF">Mal33_09620</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the ExbD/TolR family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003400">
        <property type="entry name" value="ExbD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30558">
        <property type="entry name" value="PTHR30558"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02472">
        <property type="entry name" value="ExbD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV54994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="145" mass="16004" checksum="41DBCD3289EF3D68" modified="2019-10-16" version="1">MRVKSKKPEIEEGDLTPMIDMTFQLIAFFMVLINFSQTEANERVQLPSSELARPPEGEIESPIIIHVAADGTAIIGAEEISVDTMRPILNREISVLKADGKTAEDANIIIRAHKDAATGKAQEIISVCQEVGFENFLLRAKEEVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPP0</accession>
    <name>A0A518IPP0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_10270</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="56" mass="6442" checksum="A619C77064B8B5B8" modified="2019-10-16" version="1">MLGKLLIGFSFNQWWRGASRELADYYNKMDTTQWGIIASLFVVAGFLLLRSSALKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPS2</accession>
    <name>A0A518IPS2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Phosphatidylglycerol lysyltransferase</fullName>
            <ecNumber evidence="8">2.3.2.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">mprF</name>
        <name evidence="8" type="ORF">Mal33_10410</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.3.2.3" evidence="8"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050071">
        <property type="term" value="F:lysyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024320">
        <property type="entry name" value="LPG_synthase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09924">
        <property type="entry name" value="LPG_synthase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="LPG_synthase_C" evidence="7">
        <location>
            <begin position="31"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF09924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV55072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="345" mass="39452" checksum="F2C22BB7EF2FDCC8" modified="2019-10-16" version="1">MSAVMTNLDATYPEGSQSFPREQRDLLVDFLKRFGERCVGYSTLQPGLEYFIDEEKGYIAYQSFRHPVLALTGRKMILSNPVCDPADYRAITQAFLAQHPKAIFLQVDQHYASVLEGMGLQVNCFGIETELPIDGFSLDGKLRSKLRQWRNKCQREQVVVEHCKISDVDPAEIRSLSDAWLKNRSGREFTLLMRPFQGRDEEDVYFLTARQRGELIGMTSFDPIYRNKKIVGYYHNLDRICAQAPHGTSAFCVLEAIKQFAEAEIEYVSLGFSPLYGLQEQYRHSRVARFSLGFAYEHLNFLYPFKGNAVHKKKFGGVAKPVYLSSTQGNSIRELLSIIKTLKLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPS4</accession>
    <name>A0A518IPS4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Serine/threonine-protein kinase PknL</fullName>
            <ecNumber evidence="5">2.7.11.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">pknL</name>
        <name evidence="5" type="ORF">Mal33_10460</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.11.1" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="356"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="4">
        <location>
            <begin position="51"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="16"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="313"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="378"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="320"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV55077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="737" mass="80580" checksum="7C56F4B96BD189F3" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPX9</accession>
    <name>A0A518IPX9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_11200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="247"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="266" mass="29811" checksum="006453D6DBCD64A7" modified="2019-10-16" version="1">MLDPSNNLLVQANPPFRYLKQFNSEEFAKKASCRDRLRQSDTRWFPGDYLSSVFARELCERQALPFKEVLESFEFFACVRNRIRSKSIADLCCGHGLVGILFAMFDRDVEDVCLLDKVRPPSFDLILAAAQAVAPWTEAKIRYVEAPLKRALDHLDSGTAILGVHACGAKTDQCIAHAISLRGTVALLPCCRQHRLHPAPECLKNVLGADVAIDVDRTYRMHAEGYRVRWDYISPSITEMNRVLIGRPQPQIDPTPDTPAVASASQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPZ5</accession>
    <name>A0A518IPZ5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_11270</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="74" mass="8602" checksum="FA6E271DE44BDE5F" modified="2019-10-16" version="1">METSDLALNQRIAVKAHWLKGRIVWGTVERTFHSERYKGENDWMKKHGGLKDGTFLFKPDNDGHHRLVQLSDVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQ14</accession>
    <name>A0A518IQ14_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Uroporphyrinogen-III C-methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.107</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">nasF</name>
        <name evidence="8" type="ORF">Mal33_11510</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.1.1.107" evidence="1"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004851">
        <property type="term" value="F:uroporphyrin-III C-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004852">
        <property type="term" value="F:uroporphyrinogen-III synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019354">
        <property type="term" value="P:siroheme biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06578">
        <property type="entry name" value="HemD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11642">
        <property type="entry name" value="SUMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10090">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000878">
        <property type="entry name" value="4pyrrol_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036108">
        <property type="entry name" value="4pyrrol_syn_uPrphyn_synt_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003754">
        <property type="entry name" value="4pyrrol_synth_uPrphyn_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014777">
        <property type="entry name" value="4pyrrole_Mease_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014776">
        <property type="entry name" value="4pyrrole_Mease_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006366">
        <property type="entry name" value="CobA/CysG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003043">
        <property type="entry name" value="Uropor_MeTrfase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02602">
        <property type="entry name" value="HEM4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00590">
        <property type="entry name" value="TP_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53790">
        <property type="entry name" value="SSF53790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69618">
        <property type="entry name" value="SSF69618"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01469">
        <property type="entry name" value="cobA_cysG_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00839">
        <property type="entry name" value="SUMT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TP_methylase" evidence="6">
        <location>
            <begin position="24"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="HEM4" evidence="7">
        <location>
            <begin position="287"/>
            <end position="511"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV55181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="518" mass="55673" checksum="4BF0FAB1A5CAF1C2" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQ42</accession>
    <name>A0A518IQ42_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_11860</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="37" mass="4194" checksum="3BC4C7D4753626DD" modified="2019-10-16" version="1">MAAESFGSKKVQSKYVERKSCATIDRDSFAEEIRLDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQD1</accession>
    <name>A0A518IQD1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">N-succinylarginine dihydrolase</fullName>
            <ecNumber evidence="2">3.5.3.23</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">astB</name>
        <name evidence="2" type="ORF">Mal33_12750</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.5.3.23" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009015">
        <property type="term" value="F:N-succinylarginine dihydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006525">
        <property type="term" value="P:arginine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01172">
        <property type="entry name" value="AstB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037031">
        <property type="entry name" value="AstB_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007079">
        <property type="entry name" value="SuccinylArg_d-Hdrlase_AstB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04996">
        <property type="entry name" value="AstB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0056">Arginine metabolism</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="444" mass="48258" checksum="EA90BBF5036101D9" modified="2019-10-16" version="1">MTISEINFDGIVGPTHHFGGLGIGNLASHRHAGEVANPRAAALQGLDKMATLARLGCRQAVLPPQPRPDLGLLRACGFEGTPAEIIGRASQAAPSLLSAAYSASSMWAANAATVTRSNRGGDRRTHFSPANLVSSLHRSIEPQWTTAVLREIFADASFCVHDPLPPATPLRDEGAANHMRLSDPSGDDSWDLFVYGEAQGTRFPPRQAEAACQAIARRHQLPPQRTLFLQQHPAAIEAGAFHNDVVATSCENVLLYHQLAFEDAEPALDQLAADFQKSTGGPLYRIEIAADDFSLADAIDTYLFNSQIVRAGDDRDGSLRLISPLACQQHPRARAAIDKILADPNPITAVEFVDLRESMNNGGGPACLRLRVPIDDGQLEKIPASLIWSPQLDDRLRAWVISHYPTKLTLDDLGDFDRIEQTQQAMRELSSILNLQSIRPDVSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQD6</accession>
    <name>A0A518IQD6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative periplasmic serine endoprotease DegP-like</fullName>
            <ecNumber evidence="4">3.4.21.107</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">mucD_1</name>
        <name evidence="4" type="ORF">Mal33_12670</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S1C family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.107" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001940">
        <property type="entry name" value="Peptidase_S1C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13180">
        <property type="entry name" value="PDZ_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00834">
        <property type="entry name" value="PROTEASES2C"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021821441" evidence="2">
        <location>
            <begin position="40"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="3">
        <location>
            <begin position="336"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV55297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="650" mass="69155" checksum="C3781F1E3DC34F49" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQT8</accession>
    <name>A0A518IQT8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ATPase_AAA_core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_14280</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13304">
        <property type="entry name" value="AAA_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATPase_AAA_core" evidence="1">
        <location>
            <begin position="48"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="428" mass="48304" checksum="B776B4B0E45E775F" modified="2019-10-16" version="1">MLIEVRIENYRSIREERALTLEAANLGNEDDKRPRSVKGHDAKLLPAAVIYGPNASGKSNLLLALGFIRSAVLDSQRGWEPDGGVPRPAFAWGDMRSKPSLFEVTFLKEDVKYNYGFVVDDNEVLEEWLNAWPIGHKQKWFVREKNEFKFGENLKGPNHSAREITRNNALFLSAAAQSNHSQLAPLYAWFRDLIPFRMKNELSFYRRSMGGLNHLLFPGTEAPPLAPHEVGDSATLVTKIRQLLRSADIGICDIKRTQHEFKTGDESYVRHRIMLQHQVGDDQSWLDLNDESDGTQTLFQMAPSIFKALDTGGLLLIDELESSLHPLLGLAIVRLFNAPETNPNNAQLIFTTHDTNLLGSTLGEPPLRRDQIWFIEKDKTGGSVLYPLTDYKPRQTENIERGYLQGRYGAIPFLGDMSFLGKETNGKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IR61</accession>
    <name>A0A518IR61_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Demethylmenaquinone methyltransferase</fullName>
            <ecNumber evidence="5">2.1.1.163</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ubiE_2</name>
        <name evidence="5" type="ORF">Mal33_15640</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.1.1.163" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043770">
        <property type="term" value="F:demethylmenaquinone methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102094">
        <property type="term" value="F:S-adenosylmethionine:2-demethylmenaquinol methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102955">
        <property type="term" value="F:S-adenosylmethionine:2-demethylmenaquinol-7 methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102027">
        <property type="term" value="F:S-adenosylmethionine:2-demethylquinol-8 methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004033">
        <property type="entry name" value="UbiE/COQ5_MeTrFase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01209">
        <property type="entry name" value="Ubie_methyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="243"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="246"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV55587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="276" mass="31289" checksum="2D3BA8789E76E570" modified="2019-10-16" version="1">MTISSDLKTLLQLALPIRGETHQQRLESFYGKQADNYDLFRKRLLHGREQLWQSIPIPQGGRWVDFGGGTGANVESIANRLPQLERLEIVDLSSSLLQVAMQRIADRGWKNVVTHCCDVTTFTPDAAADIVTFSYSLTMIPDWFAAVENALRILKPGGLIGVVDFYVSRKYPAADHRRHGVVTRAFWPTWFAKDNVFLSPDHLPFLSSKFESTDRHEDRGGLPFIPFVSVPYYRFVGRKPISPQSNPAEREATWAGQNERNCISSEPNIRPVETCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRE0</accession>
    <name>A0A518IRE0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FAD dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_16310</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039650">
        <property type="entry name" value="HdrA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43498">
        <property type="entry name" value="PTHR43498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022175494" evidence="1">
        <location>
            <begin position="19"/>
            <end position="752"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="752" mass="81986" checksum="D81BCB4303B59C1B" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRF1</accession>
    <name>A0A518IRF1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_16220</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021776781" evidence="1">
        <location>
            <begin position="34"/>
            <end position="573"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="573" mass="62071" checksum="F980FB18345E1BCC" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRI5</accession>
    <name>A0A518IRI5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Metal-dependent carboxypeptidase</fullName>
            <ecNumber evidence="1">3.4.17.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_16420</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of a C-terminal amino acid with broad specificity, except for -Pro.</text>
            <dbReference type="EC" id="3.4.17.19"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="2">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M32 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.17.19" evidence="1"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004181">
        <property type="term" value="F:metallocarboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001333">
        <property type="entry name" value="Peptidase_M32_Taq"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34217">
        <property type="entry name" value="PTHR34217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02074">
        <property type="entry name" value="Peptidase_M32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006615">
        <property type="entry name" value="Zn_crbxpep_Taq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00998">
        <property type="entry name" value="CRBOXYPTASET"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="1 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="active site" description="Proton donor/acceptor" evidence="3">
        <location>
            <position position="268"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="267"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="271"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="297"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR006615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR006615-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR006615-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV55663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="503" mass="56760" checksum="963AEF80BF1B5235" modified="2019-10-16" version="1">MNGNETFDQLAKFTRETALLESISYTLEWDERTYMPTGGRAYRADQVTYLAGMAHRRRTDPQMGDWIAELQQSELAGDRHSDAGATIHRIGRDFERACKLPQDLVEALSRATVVGQQRWEDARKADDFAAFLPALEEIIRLKIESAERLADGGNLYDALLDEYEEDAKSEQLTEVFRDLRSELVPLVAAIRDAKTQPNTDLLRRNFPVDAQRKFCMQAAEAVGFDFTRGRLDETSHPFCTSLGPSDCRILTRYDAHWFPGALYGTLHEAGHGIYDQGLRGDQFGLPPGTYVSLGIHESQSRMWENMVGRSLPFCQHFYGDLQRTFPEALSDVDVNAFHFAVNTVEPSLIRVEADEVTYNLHIIIRFELEQALISGDLKPKDLPDAWNQKYQEYLGITPPNNANGVLQDVHWSAGLLGYFPTYTLGNLIAAQLFDAAGEALGDLDAMFAKGEFTPLRSWLNENIHRHGRVYSPNELVQRATGKPITSQPLVGYLKRKFGSLYNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRJ0</accession>
    <name>A0A518IRJ0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Mycothiol S-conjugate amidase</fullName>
            <ecNumber evidence="1">3.5.1.115</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">mca_1</name>
        <name evidence="1" type="ORF">Mal33_16950</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.5.1.115" evidence="1"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003737">
        <property type="entry name" value="GlcNAc_PI_deacetylase-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024078">
        <property type="entry name" value="LmbE-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12993">
        <property type="entry name" value="PTHR12993"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02585">
        <property type="entry name" value="PIG-L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102588">
        <property type="entry name" value="SSF102588"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="244" mass="26545" checksum="4B1028FEEE46BDEB" modified="2019-10-16" version="1">MNADLSQYPELDVIAVGAHPDDVEIACGGTLARLVDQGYRVGIIDLTDGEPTPNSAGPEVRLQEAQAAAAALGVQVRTILDLPNRRLFDCFESRVALATEFRKHRPKLVIGFGDKTPMASPDHWQAMQITDAAIFYSRLSKWDSHFGGFPVHTISRQLYFRLAVEPDHLSGCLSHLTVDISSTLQRKLDSVACYQTQFAHKPQIMQRITAAAQITGSAAGVEAGEVFASPKSIAVDDLFKTAVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRN2</accession>
    <name>A0A518IRN2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein-glutamine gamma-glutamyltransferase</fullName>
            <ecNumber evidence="3">2.3.2.13</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">tgpA_1</name>
        <name evidence="3" type="ORF">Mal33_16920</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.3.2.13" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003810">
        <property type="term" value="F:protein-glutamine gamma-glutamyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025403">
        <property type="entry name" value="DUF4129"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021878">
        <property type="entry name" value="TgpA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002931">
        <property type="entry name" value="Transglutaminase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13559">
        <property type="entry name" value="DUF4129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11992">
        <property type="entry name" value="TgpA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01841">
        <property type="entry name" value="Transglut_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00460">
        <property type="entry name" value="TGc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="112"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="183"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="TGc" evidence="2">
        <location>
            <begin position="473"/>
            <end position="560"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="767" mass="87062" checksum="0E6AAAE7AC294655" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRP1</accession>
    <name>A0A518IRP1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_17370</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="160" mass="16218" checksum="36ECB85E2F3A1C0A" modified="2019-10-16" version="1">MTNSNVFAFIAMGVITLAGCSRGNGFPPPVPVSGSVSYQGKPVDGASITFLAGDGGGRSASGTTDSQGAFQLTTFSTSDGALPGDYTVTIAKMESKIGGDMDASNPGADYNQMMAAAGSSNLAKLQKAILPEKYADATKSGLKRSVVDGQANEFAFELGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRQ2</accession>
    <name>A0A518IRQ2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Chromosome partition protein Smc</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">smc_1</name>
        <name evidence="10" type="ORF">Mal33_17400</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011429">
        <property type="entry name" value="Cyt_c_Planctomycete-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011044">
        <property type="entry name" value="Quino_amine_DH_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07635">
        <property type="entry name" value="PSCyt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50969">
        <property type="entry name" value="SSF50969"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="SSF50978"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0349">Heme</keyword>
    <keyword evidence="4 6" id="KW-0408">Iron</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 5" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Cytochrome c" evidence="9">
        <location>
            <begin position="37"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="870"/>
            <end position="911"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="912"/>
            <end position="953"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="685"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="579"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="685"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="717"/>
            <end position="732"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV55761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1038" mass="109863" checksum="5C124942EAB4B6E9" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISB0</accession>
    <name>A0A518ISB0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HTH-type transcriptional regulator NmtR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">nmtR</name>
        <name evidence="2" type="ORF">Mal33_19220</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00778">
        <property type="entry name" value="HTHARSR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50987">
        <property type="entry name" value="HTH_ARSR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="4"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="109" mass="12031" checksum="2F528040F3BE5013" modified="2019-10-16" version="1">MSDPNLNDETRCAVYLKALADSLRLQIIRALQNGPLSVSDLALALDQEIGTVSHHLRVLYHADLVTTEREGKFIYYSLNKQVLGGKSKARRGALDFGCCKLDMGPIART</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISD4</accession>
    <name>A0A518ISD4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sugar phosphate isomerase YwlF</fullName>
            <ecNumber evidence="3">5.3.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ywlF_1</name>
        <name evidence="3" type="ORF">Mal33_19780</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LacAB/RpiB family.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.-" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016861">
        <property type="term" value="F:intramolecular oxidoreductase activity, interconverting aldoses and ketoses"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1400.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004785">
        <property type="entry name" value="RpiB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003500">
        <property type="entry name" value="RpiB_LacA_LacB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036569">
        <property type="entry name" value="RpiB_LacA_LacB_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02502">
        <property type="entry name" value="LacAB_rpiB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005384">
        <property type="entry name" value="RpiB_LacA_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89623">
        <property type="entry name" value="SSF89623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01120">
        <property type="entry name" value="rpiB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00689">
        <property type="entry name" value="rpiB_lacA_lacB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="71"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR005384-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="157" mass="16855" checksum="4FC9E2E94EF00C05" modified="2019-10-16" version="1">MSNASSLIYAIGGDHAGFPLKSVVTQTLTDQHLQIIDCGAHDETSSDFPDFALAVGEAIRSGKADRGILVCGSGVGVSVAANKIPGIRAALCHDSYSARQGVEHDDMNVLCIGARIIGPELAMECIRAFMNARYTPSERHARRLAKLLEIEKRFMKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISN5</accession>
    <name>A0A518ISN5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">3-dehydroquinate synthase</fullName>
            <ecNumber evidence="4">4.2.3.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">aroB_1</name>
        <name evidence="4" type="ORF">Mal33_20860</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="4.2.3.4" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003856">
        <property type="term" value="F:3-dehydroquinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030960">
        <property type="entry name" value="DHQS/DOIS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01761">
        <property type="entry name" value="DHQ_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DHQ_synthase" evidence="3">
        <location>
            <begin position="88"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV56107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="385" mass="42185" checksum="2CD4BF5AE24D0266" modified="2019-10-16" version="1">MLMKSSDSIDISFSLPLVQRLRFTADVFGDDAQVLIDLMEPSGDSPARAQVWLDQQVADANPGIDQRIAATLQGAADHVLLTQPPQTLVGGEACKNDPAIIDNLLRNFNDHDLDRRSYVIVIGGGAVLDTVGYAASIAHRGIRLIRIPTTTLAQADSGVGVKNAVNWFGKKNWKGTFNVPWGVINDAKILETLPDRDFRCGFSEVVKVSLLKQTEAFEQVCRDAEKICQREPQAAGDAIRASVQMHLDHITRGGDPFETREARPLDFGHWSAHRLESLTNYELRHGEAVSIGLAIDCLYSARVLGLPQADCDRILDCLQRLGLPIHHAALADTEPLLQGLEEFRQHLGGRLTITLIDAIGSPVDVHEIDHAAMREAIDATATYAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISN6</accession>
    <name>A0A518ISN6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">3-oxoacyl-[acyl-carrier-protein] synthase 2</fullName>
            <ecNumber evidence="4">2.3.1.179</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">fabF_4</name>
        <name evidence="4" type="ORF">Mal33_20900</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.179" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000794">
        <property type="entry name" value="Beta-ketoacyl_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11712">
        <property type="entry name" value="PTHR11712"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PKS_KS" evidence="3">
        <location>
            <begin position="7"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV56111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="420" mass="44083" checksum="749C5AD6683ECD63" modified="2019-10-16" version="1">MVLRKDVVITGIGVVSPIGTGVDRFWSSLVEGRSGIRELTHVTPEMLPYTYGGQLNGFDPKAYVRPRKTLKVMSRELQTAFSACVMATQQSGFDAAGTPKERIGTVFGSEMLYGEPEEIQPTVARSSPDGRFQPELWGQSAMKEIFPLWMLKYLPNMAACHYGIAIGALGPNNTIVMGDTSGLSAVAESISVIQRGAADVVVTCSTGTRVSLTRLLYQGSVPYGSRRDPLESSSRPFASERDGLIGGEGAAAVILESREHAERRGANVIATVAGYSCNYGAPAPGERGSAAALTQAIQYAIERAGATPEEIGIAISHAMGDPMLDKIDAQVHSSIVPNAIVTAPKGATGHTGAGCGVMEMCTAALALKHGVVPPTVNADLKEPQYGIDLAATARPTDATLAVQSNHSATGNAIAVVLRKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISQ3</accession>
    <name>A0A518ISQ3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_20880</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022070748" evidence="1">
        <location>
            <begin position="21"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="402" mass="46057" checksum="CFB254B98F7704B3" modified="2019-10-16" version="1" precursor="true">MPVRKLAAFLVAVIATVAGGHQVGAQEQPPGTWGEPDGILEFDTDFRWFETAYNADIEELSPKHRANHGWYATFDRAYMMVNRSETEASYTQGDFGWGNRLDFGYMGDDDRGWAMTYWSLTGPNVFDIDVEYRANVINTEDPQLPSAETPEVFDEYGQLLPRRDRDNHEYLERIYEVKDSLNVIEMKGFELNRTWRLESYRKGGLLEPMIGLKYVKIRDHTENDTYNVQPGLAQQADGTFAELIQESFNEQIDLNENEMYGGQFGFRYIKFYNRFTNSLDLRAFAMQNFQNNAYINRTTDTYYDIALQGEIDGEIAFDDSRHDTVYAHGSEFVFGFDVRAESSLQLTRDINLRAGVQVIDFAQGILRGQVRNPNGTSLVGSTAVNDQNVWLVGYTFGLTINR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISR1</accession>
    <name>A0A518ISR1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_20890</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="50" mass="5707" checksum="2AAA2D0721B28F51" modified="2019-10-16" version="1">MRCQLFAAGSQGSQFIQLLRQAMSQGTLWTQFVQHFFNPIKGRFVLFAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IT29</accession>
    <name>A0A518IT29_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_22300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="233" mass="26008" checksum="4728584FAE57A732" modified="2019-10-16" version="1">MKDDDKYSPPEASLGDHAHTLARAGVGSIPLAGAAATELFQKLIAPPLEKRRQEWMESVAEGLRQLEEQQRLSLDDLSENDTFIDAVMSASQAAIRTSQAEKREALKNAVLNSSLPDPPDESRQQIFIGLVDSLTVWHLRILRFFCDPARVFHEQGKTAPQYHLAGSLSQLLKTAYPELGNERELYDQIGKDLYGRGLLGTEGFHTMMSGNGVYEKRTTTMGDQFLRFISEPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IT99</accession>
    <name>A0A518IT99_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glucose--fructose oxidoreductase</fullName>
            <ecNumber evidence="3">1.1.99.28</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">gfo_5</name>
        <name evidence="3" type="ORF">Mal33_22750</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.99.28" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047061">
        <property type="term" value="F:glucose-fructose oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043906">
        <property type="entry name" value="Gfo/Idh/MocA_OxRdtase_bact_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19051">
        <property type="entry name" value="GFO_IDH_MocA_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GFO_IDH_MocA" evidence="1">
        <location>
            <begin position="41"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="domain" description="GFO_IDH_MocA_C2" evidence="2">
        <location>
            <begin position="209"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="481" mass="53554" checksum="D51E600F2A1CF364" modified="2019-10-16" version="1">MMSRPSRRSFLKRAAASGFAASVTISGTKSSGQVIGANDRVRVAVAGINGRGQIHMGSFAAIKDVEVTHLVDPDSRLFASRSARLERQTGQKPKCVQDIRQVLEDPTVDAVSIATPNHWHALMTVWACQAGKDVYVEKPCSHNIYEGRRMVQAAEKYNRIVQHGTQWRSDPKWRTYTADIRAGKYGKLKTANIQIFRPRKSIGIKTPVTPPRELDYDLWVGPGPMSPFRDNLVHYRWHWMWEYGNGEIGNLGAHEFEMARWAMPENASPQSVISLGGRYGYKDQAETPNTQLTLYDFGETKLVCQQRGLHFDKPLKMSIDFHTADGVIREGHFYPHGKTQGEAIVGAPPSGLPENHARAHFKNFIDCVRSRNQAELASDVLDGHRTAVLAHLGNISYRLGEPTSFSGPPEGIAAHNIASESFDDMKRHLVDAGGVNLSKDSYQLGPLLRFDAQAEEFVAATEANQMARGSYRESFQMPDIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITB0</accession>
    <name>A0A518ITB0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_23000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="123"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="168"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="196"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="222"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="418" mass="46098" checksum="11E015286D302504" modified="2019-10-16" version="1">MSHRIDWVRRAVCVSLMVLVAATWRLWFSPEPFPQIPLLRIAIDLPPAIDPIAAAVMLIAGLAALTLRSVRLQTIALSTAAISLAFLFIGDQHRLQPWAYQIFWMLIAMACCRAAVAMRMMRILVVSIYLFSGISKLDYQFVYTIGRDFLGGLVGMAGQSIEGWPETLLVAATLSFPIGELAIAVALVFARTRGAAVLAAIAMHLTLFVLLGPLGLNHQPGVLIWNLVSATLVGLLFWKVGNGEGVNARNTAEDEKVLRAEPRGHFQPLAVVMLAAVSAAPLLEPFGFYDHWLAWGLYAPHNSRVRLLIDERSIDQLPASLQQHAVPIAAGSSTRQVNLDRWSIDCLSVPIYPQARFQAGVALAVLQQSQLTNGFRLELQSASNRRDGQRTIQEIGNQDQLKLQLSRFRFNGLPRSKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITF0</accession>
    <name>A0A518ITF0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Tetratricopeptide repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_23540</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
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    </dbReference>
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    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021778887" evidence="3">
        <location>
            <begin position="35"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="584"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="511"/>
            <end position="542"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV56365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="645" mass="72767" checksum="D1A7CF1BA76F84B3" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITI2</accession>
    <name>A0A518ITI2_9BACT</name>
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        <submittedName>
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        </submittedName>
    </protein>
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            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
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                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
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            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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        <location>
            <begin position="120"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="229" mass="24588" checksum="54EEE3F9170AEF95" modified="2019-10-16" version="1">MAQREELCLLLKDLLRRLSPDDSGWGRMYQRTFVAYLTKAAPLWGSVGLPVCIAVKKQGDTEYQNLSVRHPAMLSGGSTTLLRGPYVYGDTTIVLALKACIEYVETAGSGEAATSVPKFDAHADKAPGSGSQSLQHAGESGTKDGSRKPRHDWEALQGKAVIKLGDPNADASGWSQQKWADFLGVPKTTLASSDLWGYLQAIADGEKVRAAGIDPGTLGNRTNRRNRSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITM2</accession>
    <name>A0A518ITM2_9BACT</name>
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        <submittedName>
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        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_24230</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="DUF6159"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="26"/>
            <end position="49"/>
        </location>
    </feature>
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        <location>
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            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="123"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="147"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="202"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
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            <begin position="230"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="285" mass="29677" checksum="AF63EF1B5C2E7860" modified="2019-10-16" version="1">MFERLSNGYALAKQSLGVLQRDKQLIIFPLLSGISCTLVMISFAIPLVMTGAVENAIEQGQEAGDPMQNPLYLAVLFAFYFVNYFVIVFFNSALIACAVKSFYGERPTLSDGISAAMSRLPQIAGWALLSATVGVILRVIESRSEKVGAIVSGLLGMAWAAASFFVVPVLVIEKAGPFEALKRSATILKSTWGESLGAKGGIGFFGFLASLPCIALIVGGGFLTASIGAAGIAVIVLGVIGLLLVSLISSAMSAIVQAAIYMYGSSGDAPGGFEANNLRGVFAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITP2</accession>
    <name>A0A518ITP2_9BACT</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">Mal33_24380</name>
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        <dbReference type="NCBI Taxonomy" id="2527990"/>
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            <taxon>Planctomycetia</taxon>
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        </lineage>
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    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    <keyword evidence="1" id="KW-0472">Membrane</keyword>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
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        <location>
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            <end position="35"/>
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        <location>
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            <end position="67"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
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            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="151"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="308" mass="33897" checksum="A3E88106393B0279" modified="2019-10-16" version="1">MGLYRHSGRVPITGLILCSLLLTPLAIFGGAAYSAAMVFLPFIKLKWLISLLFAAAAGFIVGKVCLAGKVRNRGFVILATVSTMGLAYYVSWGVQRFWLVVGELGFEGAIDNVGLADLLPISLAAWVTWLFENGLWSMRGGADTIKGWPLVALWGIEAATLFVTSWTLALGTYGFRPFCEACERWTTLDVGIAELPVDVDDPAWAEVRDGRFEALRHLKINPAEDRHARIDLATCPECETSDHVLISGVVYAVDKEGNLTANETPIIEYLHMTREKTNELREFAAELNEAVELMRADEEALSEEPTDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITS7</accession>
    <name>A0A518ITS7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_24820</name>
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        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetia</taxon>
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    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045919">
        <property type="entry name" value="DUF6338"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19865">
        <property type="entry name" value="DUF6338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="13"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="212" mass="23715" checksum="DF8514E8F5F6A03A" modified="2019-10-16" version="1">MGISKDVVVLLEYLLPGFIAAWVFYGLTGHPKTSPFERTVQALIFTVIIKAITHCIGWIALTIFTVTGLSVGTWDANAQLILSVTIAIVGGHAISWAANTNTYHKRLYKRKITTKTSLVSEWHSAFAMRDAFIILHLDADLNERKLFGWPNEWPDDPKSGHFVITEPEWLIELDNGYDRVPATADEMLLISASHVLMVEFVKSSNTETENAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITW9</accession>
    <name>A0A518ITW9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Octaprenyl-diphosphate synthase</fullName>
            <ecNumber evidence="2">2.5.1.90</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ispB_1</name>
        <name evidence="2" type="ORF">Mal33_25250</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.5.1.90" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106350">
        <property type="term" value="F:octaprenyl pyrophosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002829">
        <property type="entry name" value="DUF116"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000092">
        <property type="entry name" value="Polyprenyl_synt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01976">
        <property type="entry name" value="DUF116"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00348">
        <property type="entry name" value="polyprenyl_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="SSF48576"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="628" mass="68656" checksum="6535A3CC6F8583B4" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IU26</accession>
    <name>A0A518IU26_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_25830</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="296" mass="31365" checksum="9F099DB141FBBEAD" modified="2019-10-16" version="1">MITSLRNAGSLHRVDTFWRLQAVRFAIATLVTAVLTAGDCCAETDEPSVISKIPAGKLITADGLQDWTNTVLVATPKVTGGEVDKVSEMVLRYAAMFTTVIAVDVQKVQGEHRLQRIGLGIAVADGEDFRIVSARDGSAGLGMIGTQVLQAAEQSLDRVTVALRLATAITIDSPALVAVGGQHEQVVARHLIWAQPKSGSVSSAVWFIRGGESPEVVDGQGMFLPENFRETRHLHVDVGEFFLGIPGPKAFAMQGLPPGKPFPLAASHAAAACATPLTIDDFKSLAQYLTAAASRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IU36</accession>
    <name>A0A518IU36_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Polyketide synthase PksJ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">pksJ</name>
        <name evidence="7" type="ORF">Mal33_25840</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pantetheine 4'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:47942"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008610">
        <property type="term" value="P:lipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05931">
        <property type="entry name" value="FAAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensatn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040097">
        <property type="entry name" value="FAAL/FAAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
            <begin position="610"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
            <begin position="1644"/>
            <end position="1719"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1742"/>
            <end position="1769"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4">
        <location>
            <position position="645"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4">
        <location>
            <position position="1679"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV56592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1769" mass="192488" checksum="07C801A2727336B6" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IU53</accession>
    <name>A0A518IU53_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">CAI-1 autoinducer sensor kinase/phosphatase CqsS</fullName>
            <ecNumber evidence="4">2.7.13.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">cqsS</name>
        <name evidence="4" type="ORF">Mal33_26130</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.13.3" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="F:protein histidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="75"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="13"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV56621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="196" mass="21346" checksum="687E22262B50DFFA" modified="2019-10-16" version="1">MKQRFLFADINSDPIGDQTPANHSHAAGISHQEPVDRDPTLDAVFSALGMDLGYLGDSQMVSDSAGDQSIDDRPWVLHVDDDDAFRNIVRLRLEAAGICVANAGDGIEGIHQAFRQRVGAIILDFEMPNGRGDYVLGRLKGNPVTMDIPVIVLTGMRDPLLSERLLEMGAAACLRKPPQFDVLIEQIEQLVCAAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IU99</accession>
    <name>A0A518IU99_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Arsenite S-adenosylmethyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_26520</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026669">
        <property type="entry name" value="Arsenite_MeTrfase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43675">
        <property type="entry name" value="PTHR43675"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13847">
        <property type="entry name" value="Methyltransf_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltranfer_dom" evidence="2">
        <location>
            <begin position="66"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="365"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="392" mass="43672" checksum="6DB5573425A2B7BB" modified="2019-10-16" version="1">MKTTTTAEAPSSESSVYDRYAAAAHAVEPALCCPVEYNTDLLAAIPQEIIERDYGCGDPTPYVRPGETVLDLGSGGGKLCYIASQVVGREGRVIGVDCNREMLDLARKHTSTVAETIGYANVDFRYGLIQDLGLDLDLLASELADHPVHDPAGYLALRQTEERLRRQHPLVDDDSVDCVLSNCVLNLVRQQDRRPLFSEIFRVLRRGGRAAISDIVSDEDVPDRLQQDPELWSGCITGAFREDKFLQAFEEAGFHGIEIVKRQSEPWRTVEGIEFRSVTVVAHKGKQGPCLERNQAVVYRGPFKKVVDDDGHTYHRGQRMAVCDKTFHLLQRAPYAKMFDAIEPRESIALEDAKAFDCRRNVCRDPRESKGLDYDATSRGNASSCSDDEPCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUK0</accession>
    <name>A0A518IUK0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8 13">Glutamyl-tRNA reductase</fullName>
            <shortName evidence="8">GluTR</shortName>
            <ecNumber evidence="4 8 13">1.2.1.70</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8 17" type="primary">hemA</name>
        <name evidence="17" type="ORF">Mal33_27570</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8 13">
            <text>(S)-4-amino-5-oxopentanoate + NADP(+) + tRNA(Glu) = H(+) + L-glutamyl-tRNA(Glu) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:12344"/>
            <dbReference type="Rhea" id="RHEA-COMP:9663"/>
            <dbReference type="Rhea" id="RHEA-COMP:9680"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57501"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="EC" id="1.2.1.70"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 8 13">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; 5-aminolevulinate from L-glutamyl-tRNA(Glu): step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="domain">
        <text evidence="8">Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="8">During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8 13">Belongs to the glutamyl-tRNA reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.70" evidence="4 8 13"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00316"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008883">
        <property type="term" value="F:glutamyl-tRNA reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00087">
        <property type="entry name" value="Glu_tRNA_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000343">
        <property type="entry name" value="4pyrrol_synth_GluRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015896">
        <property type="entry name" value="4pyrrol_synth_GluRdtase_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015895">
        <property type="entry name" value="4pyrrol_synth_GluRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018214">
        <property type="entry name" value="GluRdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036453">
        <property type="entry name" value="GluRdtase_dimer_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036343">
        <property type="entry name" value="GluRdtase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006151">
        <property type="entry name" value="Shikm_DH/Glu-tRNA_Rdtase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00745">
        <property type="entry name" value="GlutR_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05201">
        <property type="entry name" value="GlutR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01488">
        <property type="entry name" value="Shikimate_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000445">
        <property type="entry name" value="4pyrrol_synth_GluRdtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69075">
        <property type="entry name" value="SSF69075"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69742">
        <property type="entry name" value="SSF69742"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01035">
        <property type="entry name" value="hemA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00747">
        <property type="entry name" value="GLUTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8 11" id="KW-0521">NADP</keyword>
    <keyword evidence="6 8 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7 8 13" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GlutR_N" evidence="16">
        <location>
            <begin position="6"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="Shikimate_DH" evidence="15">
        <location>
            <begin position="173"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="domain" description="GlutR_dimer" evidence="14">
        <location>
            <begin position="322"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8 10">
        <location>
            <begin position="49"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8 10">
        <location>
            <begin position="115"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="8 9">
        <location>
            <position position="50"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 11">
        <location>
            <begin position="191"/>
            <end position="196"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for activity" evidence="8 12">
        <location>
            <position position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000445-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000445-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000445-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000445-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF01488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF05201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="QDV56758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="426" mass="47779" checksum="F393F4A2F283D1EA" modified="2019-10-16" version="1">MKLQMIGCSHHQANVEFREQLSFTGDQAQIALDAFRDRFPKTEAVLLSTCNRVEFYTATDDDSGVEQAQFIDFLADQRGLAQDQLMEHLICRNGNEAIEHLFTVAASLDSMVVGEPQILAQVKQAYELACTQGSAGPLTHSIFQTASRVAKRVASETAIHKKRVSIPSVAVGEIAVEFFERMDDKRIVLIGAGEMGRETLQYLRDKGARDVRLINRHRQRADEAAAELGARSAAWEDMHELLADADLVVSTTAATEPIMDVQRFGAIHQARYGRMLLILDLAVPRDFDPKIGELSGVYLYSVDDLQAACHRNQREREKEWPKAKRIIEDETRDFVTALHHRATGPVIKRLREQTEQVKQDELARLIGRLESAGASDEIRREVTQAFDRLVNKMLHPPMASLKDDVASGGNHGLLDALRKLFQLNDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUP6</accession>
    <name>A0A518IUP6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">General stress protein 16O</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">yocK</name>
        <name evidence="6" type="ORF">Mal33_28080</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037187">
        <property type="entry name" value="DnaK_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000962">
        <property type="entry name" value="Znf_DskA_TraR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020458">
        <property type="entry name" value="Znf_DskA_TraR_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01258">
        <property type="entry name" value="zf-dskA_traR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109635">
        <property type="entry name" value="SSF109635"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01102">
        <property type="entry name" value="ZF_DKSA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51128">
        <property type="entry name" value="ZF_DKSA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DksA C4-type" evidence="5">
        <location>
            <begin position="42"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="dksA C4-type" evidence="4">
        <location>
            <begin position="85"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV56808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="132" mass="14562" checksum="6C9FEC5BFFB3B4DD" modified="2019-10-16" version="1">MARTQAILKLRQLLVRRRDALRRVLAGDLSSLNELREQSHGDVLDAASDTARDELSSQLAEVESRELGQIDDALLRMRDGSYGSCDGCGKVIPVARLQIVPYATECIECKRKSEGTDVGGGWSWDRSEVDSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUR3</accession>
    <name>A0A518IUR3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptide-methionine (R)-S-oxide reductase</fullName>
            <ecNumber evidence="2">1.8.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">msrB_1</name>
        <name evidence="6" type="ORF">Mal33_28300</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[thioredoxin]-disulfide + H2O + L-methionyl-[protein] = [thioredoxin]-dithiol + L-methionyl-(R)-S-oxide-[protein]</text>
            <dbReference type="Rhea" id="RHEA:24164"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="Rhea" id="RHEA-COMP:12313"/>
            <dbReference type="Rhea" id="RHEA-COMP:12314"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16044"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:45764"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.8.4.12"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="1.8.4.12" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033743">
        <property type="term" value="F:peptide-methionine (R)-S-oxide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030091">
        <property type="term" value="P:protein repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028427">
        <property type="entry name" value="Met_Sox_Rdtase_MsrB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002579">
        <property type="entry name" value="Met_Sox_Rdtase_MsrB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10173">
        <property type="entry name" value="PTHR10173"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01641">
        <property type="entry name" value="SelR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="SSF51316"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00357">
        <property type="entry name" value="TIGR00357"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51790">
        <property type="entry name" value="MSRB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MsrB" evidence="5">
        <location>
            <begin position="64"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="32"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="32"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV56829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="200" mass="22514" checksum="D342CB4A084FADAA" modified="2019-10-16" version="1">MIVSKNHWRWVTGTTTVAITLWTLSMGNLTSRADDGQSKAPASATESSDSKWGPNAPPYTPKTKRELRKTLTRMQYSVTQQADTERAFTGPYWDSKQDGIYTCVVCGLPLFDSSTKFKSGTGWPSYWQPIREGNVGTKTDWKMLYPRTEVHCKRCKAHLGHVFNDGPQPTGLRFCMNGAALKFRERSSLEEPTAEPQSDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUR5</accession>
    <name>A0A518IUR5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Leucine Rich repeats (2 copies)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_28350</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="576" mass="64439" checksum="30B43F2DB061CF37" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUU0</accession>
    <name>A0A518IUU0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Undecaprenyl-phosphate mannosyltransferase</fullName>
            <ecNumber evidence="2">2.4.1.54</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_28500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.4.1.54" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047267">
        <property type="term" value="F:undecaprenyl-phosphate mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="69"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="297" mass="33325" checksum="21E75CE572F31751" modified="2019-10-16" version="1">MPEHDPTPERNETPTREVLFGEGLTVPQDLDGNPRFWTDEHYLECCRLLGPAVCRRLGIFPLPAGFVLSVVVPVYNEATTVERAIARLRSTGLPLQIILVNDGSTDGSHEVLDALPASDDLTVIHHPANAGKGAAVRTGFAAAKGDCVVVQDADLEYDPNDFRWLLQPLVAGEADVAYGTRYGHCDRQVSPWWHQAVNGLITGLCNLAIGLRLSDVETCYKMVRRDLLQDLVPDLKENRFGIEIELTAKLAKRRLRFTERPIRYQHRWYDEGKKIGWKDGVSALWCIVRYGLLQRSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUY0</accession>
    <name>A0A518IUY0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_28880</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014755">
        <property type="entry name" value="Cu-Rt/internalin_Ig-like"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021850165" evidence="2">
        <location>
            <begin position="27"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="493" mass="53860" checksum="2B5A5AD44B14B4E3" modified="2019-10-16" version="1" precursor="true">MNRFPVATTLFSGLLIGLCVTATAVAQPPTEEDFYKLTDLQIPEGELLEVGAVQLMSDGRLAAATRRGEIWMIDAPLADEVPAKNFHRFAHGLHEPLGLTEKEGWLYVTQRPDVSRLRDTDGDGRADEFEVVADGWGITGDYHEYAFGSKFDANGDIWVTLCLTGSFSSKALYRGWCVRVTPDGKTVPTTSGIRSPGGMGSNLAGDIFYTDNQGPWNGTCHLKQLIPGKFVGHPGGFEWYEQAEEVLGKRPQEPESNTRSLDQARKIPEFEVPVVMFPYNKMGKSASGVTCDTSGGKFGPFAGQMFVSDQSASTVMRVYLEKVQGHYQGVCFPFRKGFGSGNVATEVTSDGSMFVGGTNRGWGSAGRDPGSLQRLNWTGKVPFEILEMRAAKDGFDLQFTEPVDPETAGNVDSYKMETYTYIYQSSYGSPEVDHTTPKIVSATVADDGKTVHLEIDGLQEGHVHELHSDGVKSAAGNPLLHPEAYYTLNYLVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVC0</accession>
    <name>A0A518IVC0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ECF RNA polymerase sigma-E factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rpoE_2</name>
        <name evidence="2" type="ORF">Mal33_30330</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014326">
        <property type="entry name" value="RNA_pol_sigma-70_Plancto"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011517">
        <property type="entry name" value="RNA_pol_sigma70_ECF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07638">
        <property type="entry name" value="Sigma70_ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02984">
        <property type="entry name" value="Sig-70_plancto1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="224" mass="25219" checksum="C4C0FF68FE2813FA" modified="2019-10-16" version="1">MIATDSTHRSDSSSQSGQTQEFQSLLEAARDGDSEALGRLLQWYANYLTLLASTQLDRRLQRRLNPSDIVQEAMLAAHRDFGDFRGQSQGELLCWLRQILIHTLHRAFAANVKVAKRDVRREVSLDAVANGLENSAINLASILPNRGESPSAPMQARERAVWLADQLSELHPPYRDVIVFRVLQGMSFDEIAKRMDRSGGAVRMLWLRALEAFKTQGEARDVCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVD2</accession>
    <name>A0A518IVD2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phosphoserine phosphatase 1</fullName>
            <ecNumber evidence="1">3.1.3.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">pspA_2</name>
        <name evidence="1" type="ORF">Mal33_30480</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.3.3" evidence="1"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036424">
        <property type="term" value="F:L-phosphoserine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="SSF53254"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="217" mass="24337" checksum="265A42815F74EC35" modified="2019-10-16" version="1">MTVPQETIVQEVIMVRHGAVDPQWKGICYGAMDVSLSEQGYSDSRQVARQLSERFQPSAIFHSGLSRTRFLAEEIAQAYSGAVPCIEDHHLRERDYGDWQGQTWDAAYASDPDNFDGLIEDPDHYRPPGGETTSQMQARVAQWFNEQLNPSGHDRPKTLIAVSHSGPIAALAGHLHETPPTQWQPYTIGTLESIRVRQVASGEQTRWQVDRQTAGLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVD4</accession>
    <name>A0A518IVD4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_30520</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018676">
        <property type="entry name" value="DUF2149"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09919">
        <property type="entry name" value="DUF2149"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="117" mass="12753" checksum="DC1F1E4A552767CF" modified="2019-10-16" version="1">MNRRRIQILSSDDSDPMLSSINLVDVFLVALAILMIALMNHPLADLASGDFTLIRDEGKPTMEIIVKQGKQLSRFQSTGLSSEGNGTEAGTAYRMKDGSMVYVPKSSPSDNEHPSQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVM7</accession>
    <name>A0A518IVM7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Putative glutamate--cysteine ligase 2</fullName>
            <ecNumber evidence="2">6.3.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Gamma-glutamylcysteine synthetase 2</fullName>
            <shortName evidence="2">GCS 2</shortName>
            <shortName evidence="2">Gamma-GCS 2</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ybdK_2</name>
        <name evidence="3" type="ORF">Mal33_31350</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 2">
            <text>ATP + L-cysteine + L-glutamate = ADP + gamma-L-glutamyl-L-cysteine + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13285"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58173"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.2" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004357">
        <property type="term" value="F:glutamate-cysteine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042398">
        <property type="term" value="P:cellular modified amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01609">
        <property type="entry name" value="Glu_cys_ligase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006336">
        <property type="entry name" value="GCS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011793">
        <property type="entry name" value="YbdK"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04107">
        <property type="entry name" value="GCS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="SSF55931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02050">
        <property type="entry name" value="gshA_cyan_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 3" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00029283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="377" mass="42005" checksum="E0656447A8B46722" modified="2019-10-16" version="1">MVSFSRSKVPAVGVEEEYQLVDPTSGRLIPKCSEVLRQLGREPEADIQRELHLNQIEMASNVCETLDEVRDNLQRVRKLLIDAAANTGAALVSAGTNPFPLPESETLTPKFRYQAMGQQFQHIARSLFIFGCHVHVDMQDKTLGLHVMNQTRRWLPLLQALTANSPFWNGQDTGYASYRREVWVQWPMAGAPPHFRELDDYEACLSELTKSGAIKDESFIYWDIRLSVKVPTIEYRCADVITSLQHCVGYVGLVRALVMQTCDDIHAGREYPPIRSHLLSFAIWHAARYGVSADLLDPLTCEKVTATESAARMLEYITPSLAASGDRECVEAFVQSVVRDGCGADRQRMTMQTEGNLAAVVQAAIKETANDTSPAAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVP8</accession>
    <name>A0A518IVP8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_31560</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="260" mass="28167" checksum="F96AEC403C6F2B73" modified="2019-10-16" version="1">MSYHEYWRLHRLPFGQVNGREDFYEGTSQREAIARLRFLVGNARSVGLLIGGPGSGRSSLLRHVSRNVLWSGAIVDTILVSGRCDSQADWLHQLSTTLCADPTLHSSDAWRRICDTIDAASRQDVYTCLLVDDATNLVAESISSLINRSRHVTAVLACNTETAGGLVHRIGGCPLRIDLPHWALSDSAGFIRQSIADSGGEPELFNDAAIVRLHELSEGRVATLARLAELSLLAGAGSRATQITPEIVEAIQDEMLVAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVV6</accession>
    <name>A0A518IVV6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_32130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="165" mass="17741" checksum="A2A3B41FBF25140C" modified="2019-10-16" version="1">MNDPSRQELAEVGRPTEEHELKGDDRLFRALVSGCHVENAAVVAGISERTAYRRLADPEFRKQLDEARQSLRESILSKLADAGHDAIGVLMDLAHGSDDDAIRLKAAKALIDALLTTQRQQTAPKREQAGISANVGSLSIVVRKDSDDVGSVAIEGNGMAVGNEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IW31</accession>
    <name>A0A518IW31_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Inosose isomerase</fullName>
            <ecNumber evidence="3">5.3.99.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">iolI_1</name>
        <name evidence="3" type="ORF">Mal33_33050</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="5.3.99.-" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013022">
        <property type="entry name" value="Xyl_isomerase-like_TIM-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01261">
        <property type="entry name" value="AP_endonuc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="SSF51658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021775165" evidence="1">
        <location>
            <begin position="33"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="domain" description="AP_endonuc_2" evidence="2">
        <location>
            <begin position="64"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="319" mass="34348" checksum="518F2870A365B782" modified="2019-10-16" version="1" precursor="true">MTDASMNRRSILSIAAATTLVGSGLPTAPAKAADTATSDEFGGIRFCLNTSTVRGQELTITEQVDLAASSGYDAIEPWVRDLVAYKEAGGSLPDLRKRIEDSGITVESAIGFAQWIVDDDDQRRKGLEQARSDMELLKSIGGKRIAAPPVGATKEAGPALPVIAKRYADLLNVGAEVGVTPELELWGFSKTLSRLGELAYVATEAGHPDACVLPDVYHIYKGGSDFAGLAMIEASRMPAFHMNDYPANPPWETIGDADRVYPGDGIAPLDDIISLLHRNGFRGYFSLELFNRDYWKQPASEVATTGLRKMKSAVRKALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IW71</accession>
    <name>A0A518IW71_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase</fullName>
            <ecNumber evidence="2">2.5.1.145</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2 3" type="primary">lgt</name>
        <name evidence="3" type="ORF">Mal33_33370</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + L-cysteinyl-[prolipoprotein] = H(+) + S-1,2-diacyl-sn-glyceryl-L-cysteinyl-[prolipoprotein] + sn-glycerol 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:56712"/>
            <dbReference type="Rhea" id="RHEA-COMP:14679"/>
            <dbReference type="Rhea" id="RHEA-COMP:14680"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57685"/>
            <dbReference type="ChEBI" id="CHEBI:64716"/>
            <dbReference type="ChEBI" id="CHEBI:140658"/>
            <dbReference type="EC" id="2.5.1.145"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; lipoprotein biosynthesis (diacylglyceryl transfer).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the Lgt family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.145" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00664"/>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008961">
        <property type="term" value="F:phosphatidylglycerol-prolipoprotein diacylglyceryl transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042158">
        <property type="term" value="P:lipoprotein biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01147">
        <property type="entry name" value="Lgt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001640">
        <property type="entry name" value="Lgt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30589">
        <property type="entry name" value="PTHR30589"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01790">
        <property type="entry name" value="LGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="48"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="81"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="115"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="157"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="186"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="337"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="363"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="400"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="205"/>
        </location>
        <ligand>
            <name>1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol)</name>
            <dbReference type="ChEBI" id="CHEBI:64716"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="433" mass="46960" checksum="628448524FB205B5" modified="2019-10-16" version="1">MYRTLFFIPHEFAGIPLFGFGWLLGAIVLYAIAITIFSSRDPNRRSELFSTLGMCAIAAVVVAVVFPNVEIRNQAGEPMGMAIRGYGVMMLLGVSAAVGLAIVRARKYGLGSETIMAAAPWLFVLGILGARAFYVIEYRDRFEHESMLQMLRSIVDFTRGGIVVYGSLIGGFVGLVLFCRRHSLPFFRMADIIIPCVFIGLFFGRMGCVMNGCCYGGRCEPSAYSMQFPKGSPVYEDQARSGDLLGLVVDWGDSDKSDSARLGKIVEVVPASLAAEAGVEPGGEARIQLERPAPEDTDLTLPIDDTSGLGIAMFVDGKTYRWKADQLPQRANSVAPAQLYSSVLGLAMAVMLMVISPWIRREGALMGIGFAGYAVVRFGLESIRSDEPGQFGTGLTISQWVSIFVFVGSIGLLIYLYRRPLKTADPATVTASP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWF4</accession>
    <name>A0A518IWF4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Dipeptide epimerase</fullName>
            <ecNumber evidence="5">5.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ycjG</name>
        <name evidence="7" type="ORF">Mal33_34340</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="4 5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="4 5">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the mandelate racemase/muconate lactonizing enzyme family.</text>
    </comment>
    <dbReference type="EC" id="5.1.1.-" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016855">
        <property type="term" value="F:racemase and epimerase activity, acting on amino acids and derivatives"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03319">
        <property type="entry name" value="L-Ala-DL-Glu_epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034603">
        <property type="entry name" value="Dipeptide_epimerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036849">
        <property type="entry name" value="Enolase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029017">
        <property type="entry name" value="Enolase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029065">
        <property type="entry name" value="Enolase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013342">
        <property type="entry name" value="Mandelate_racemase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034593">
        <property type="entry name" value="Mandelate_racemase_DgoD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013341">
        <property type="entry name" value="Mandelate_racemase_N_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48080">
        <property type="entry name" value="PTHR48080"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13378">
        <property type="entry name" value="MR_MLE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02746">
        <property type="entry name" value="MR_MLE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00922">
        <property type="entry name" value="MR_MLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51604">
        <property type="entry name" value="SSF51604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54826">
        <property type="entry name" value="SSF54826"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4 5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MR_MLE" evidence="6">
        <location>
            <begin position="136"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; specific for (R)-substrate epimerization" evidence="3">
        <location>
            <position position="155"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; specific for (S)-substrate epimerization" evidence="3">
        <location>
            <position position="253"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="205"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="231"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR634603-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR634603-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU366006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV57424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="343" mass="37710" checksum="54FDA34DFC6BE85D" modified="2019-10-16" version="1">MKLQWHRIELPLKDPFTIARGTMHHQQCLIVTLSHADVTGYGEVTCNRYYGHTYESLEASLQRIEGLLADCDAVHPSDLFERCQVVIPDDTFALSAVDAAAYDLYGKLHGVRTTEALGLSEPAEICSSYTLGIDSIDQMVRKYRDQPDWPIYKIKLGTPHDLDIVRALRRETEAVIRVDANCAWTPEQTIANSEALAELGVEFIEQPLPAEAPRAAQLDVFEHSRLPIIADESCRTEEDVQKCHGLFHGINIKLCKCGGLTPGSRMLRQARQLGMKTMVGCMIESTVGISAAAQLLPLLDCADLDGATLLAEDAADGVRIENGRVIFSSVPGSGIELLARSPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWH8</accession>
    <name>A0A518IWH8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Stage II sporulation protein E (SpoIIE)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_34600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13492">
        <property type="entry name" value="GAF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07228">
        <property type="entry name" value="SpoIIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00331">
        <property type="entry name" value="PP2C_SIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GAF" evidence="1">
        <location>
            <begin position="70"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="domain" description="PPM-type phosphatase" evidence="2">
        <location>
            <begin position="239"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="453" mass="48111" checksum="C9D8A37249199847" modified="2019-10-16" version="1">MLLPACTEAMMDVDSADAQPAVSKSAAETLAQAASRIADRLREFEGLLRNQEATHAVEDANAGCLPAAGHIADRLEAVLKEASAATGCDAAGLYLLDADTSHLKLRSCFGLPKSRLAQPPRALRGALGDLEALVSPVVTIEDIPRMPHWESPEERGAAIVVAIRGGDLPLGTLWLWDDQPRDITSAQQASATLAAGRIAAELEREVIGTKAAEQAEVRDELRAAAAWQSRQLPPAVPLDKDWDVAGWNEAAEAVGGDWFAWDILPDGKIAIAIASVGASGIESALTAATARSAWQSHTGYRHKTNQVLSRVNDTLWQTSTGDQSTSLLYVTVDPETGEGQFSSAGTCQGLIVNRYGYRMLASPTEPLGRDPDVRPLVHTMRLLPGEALVLVSQGAIASNGAPESGRLTQQTLTDSIRHELVNGPEPALSCLRRLFAQAGPAAADRSIAILQRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWK3</accession>
    <name>A0A518IWK3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_34670</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036721">
        <property type="entry name" value="RCK_C_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116726">
        <property type="entry name" value="SSF116726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="62" mass="6971" checksum="F0701E26149EBCCE" modified="2019-10-16" version="1">MTLIVAILSTDGRIRRNPDTNEPILPGDILYVMSSQEKTLAVIRQVQAQRAELTYRGSRVQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWK6</accession>
    <name>A0A518IWK6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Stress responsive A/B Barrel Domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_34890</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013097">
        <property type="entry name" value="Dabb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044662">
        <property type="entry name" value="HS1/DABB1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33178">
        <property type="entry name" value="PTHR33178"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07876">
        <property type="entry name" value="Dabb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00886">
        <property type="entry name" value="Dabb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51502">
        <property type="entry name" value="S_R_A_B_BARREL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021749990" evidence="2">
        <location>
            <begin position="21"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="Stress-response A/B barrel" evidence="3">
        <location>
            <begin position="50"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV57479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="148" mass="16435" checksum="372416088571AAA5" modified="2019-10-16" version="1" precursor="true">MRFQTLASHKWFVAASLASALLGGAIMNGQLGDRSMAIADEKPAAKTQLLRHVVLFKFKESSSEADVQKVVDEFGKLKSKIPQIYAYEHGTENSPEGLADGFTHCFLVTFKSEADRAAYLPHADHLAFVDVLKPHLDKVLVVDYWTNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWQ6</accession>
    <name>A0A518IWQ6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">DUF2179 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Mal33_35420</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019264">
        <property type="entry name" value="DUF2179"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015867">
        <property type="entry name" value="N-reg_PII/ATP_PRibTrfase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003740">
        <property type="entry name" value="YitT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10035">
        <property type="entry name" value="DUF2179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02588">
        <property type="entry name" value="YitT_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="67"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="100"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="138"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="171"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2179" evidence="8">
        <location>
            <begin position="222"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF10035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV57532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="284" mass="31062" checksum="EBF928DEF1B85A12" modified="2019-10-16" version="1">MIVSAGLLYAIALKYFVLPSKVILTGSEGIAAALSYYFENYSLFIVLYLVFQAALLAFAFARVGRTFALRSLIVVGTVVLALAGLPELQFASPEPQNERIILVIFGGLLAGFAKALAFKNRGSTGDEDILGAYFAMKYLKPVGSIAIFAAVGSTAFGLGMELLKHGHIESVVNTLMYTCIYIFASAETLNNLYHKFKITMLVIITRNQEAIGEAITATSAHRTYTVQPGIGGHSGESFWMVRTIITQEELPHLVDAVEESDPSSFHYNYDIEGISRRYYITPIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWT8</accession>
    <name>A0A518IWT8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Cytochrome c oxidase subunit 2</fullName>
            <ecNumber evidence="14">7.1.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">ctaC_1</name>
        <name evidence="18" type="ORF">Mal33_35570</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>4 Fe(II)-[cytochrome c] + 8 H(+)(in) + O2 = 4 Fe(III)-[cytochrome c] + 4 H(+)(out) + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:11436"/>
            <dbReference type="Rhea" id="RHEA-COMP:10350"/>
            <dbReference type="Rhea" id="RHEA-COMP:14399"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="EC" id="7.1.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </cofactor>
        <text evidence="14">Binds a copper A center.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Cell membrane</location>
            <topology evidence="13">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the cytochrome c oxidase subunit 2 family.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.9" evidence="14"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070469">
        <property type="term" value="C:respirasome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004129">
        <property type="term" value="F:cytochrome-c oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045187">
        <property type="entry name" value="CcO_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002429">
        <property type="entry name" value="CcO_II-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008168">
        <property type="entry name" value="Cyt_C_IC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011759">
        <property type="entry name" value="Cyt_c_oxidase_su2_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036257">
        <property type="entry name" value="Cyt_c_oxidase_su2_TM_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22888">
        <property type="entry name" value="PTHR22888"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00116">
        <property type="entry name" value="COX2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02790">
        <property type="entry name" value="COX2_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00034">
        <property type="entry name" value="Cytochrom_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00605">
        <property type="entry name" value="CYTCHROMECIC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="SSF49503"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81464">
        <property type="entry name" value="SSF81464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50857">
        <property type="entry name" value="COX2_CUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0186">Copper</keyword>
    <keyword evidence="8 13" id="KW-0249">Electron transport</keyword>
    <keyword evidence="4 12" id="KW-0349">Heme</keyword>
    <keyword evidence="10 12" id="KW-0408">Iron</keyword>
    <keyword evidence="11 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 12 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="18" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="6 13 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 13" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="37"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="76"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="COX2_CUA" evidence="16">
        <location>
            <begin position="109"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="17">
        <location>
            <begin position="255"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU004024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="QDV57547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="351" mass="39988" checksum="0ACC55B006A95FD4" modified="2019-10-16" version="1">MQTLQNLSFVLADVSDGFWFPKTASNFATEVDFMYKAILWISVAFFVPMMIYMGWAAFKFQKPKGEKAEGKATHNTALELAWSVGPCFLLIWMFYRGSVGYLDMRQPPSDAREVQVTAQKWSWLFDYGSGIMNPELHVVKDQPTKLIMRSKDVLHAMYIPAFRVKRDIVPGRYNTLWFTPTIGTESLTDDEMQWKSDDPEEAGNILNQGKYFDFYCAEYCGKDHSMMQGKIVVHETQDEYDAWLESANRRPDDQTPEQYGEFLYATRGCKGCHSADGTAGQCPTFLNSFGAEHEMVDGSKVSVDENYIRESILNPKAKVVKGYPPVMPSFQGQLNDDQIDSLVAYIKSLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWV0</accession>
    <name>A0A518IWV0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_35730</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="73" mass="8567" checksum="EADC9602DFBEE459" modified="2019-10-16" version="1">MRFHRTAWKQSELAIDRFSGIVLLASLNRIVDFAAMNWHFARSFHPKPYFIATDLDDNDTNIIVDYDAFVFLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWW5</accession>
    <name>A0A518IWW5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_35890</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="63" mass="7106" checksum="F02BEE0DCBE98B64" modified="2019-10-16" version="1">MTIKMAKLVTQQLHRERLVAHQPDRVAADLAEAAVVAEAGQRGWLHWELRPQRLQVVATAALR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWZ7</accession>
    <name>A0A518IWZ7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Tryptophan halogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_36250</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006905">
        <property type="entry name" value="Flavin_halogenase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04820">
        <property type="entry name" value="Trp_halogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="491" mass="54268" checksum="D7C9F5D2CD718AEB" modified="2019-10-16" version="1">MNKEVDLLVLGSGFGGSLLSLLLARQGLRVAVIDRAVHPRFAIGESSTPLADATLKELAQRYDLPELMPLTAYGPWRRRHPDLMCGLKRGFSYFGHSRGTEFSPADQLLVAASSNDEHSDTHWLRSDVDAWLFERAADRGAMQFEGASYRLSREDSQWLVAGEASGAAFSLRAPMIIDATGAAGEVLRYLKIASQTHQLKTTSWAVYGHFENVTSVAEMLDRRQIDRRRHPFACDDAAVHLVLDDGWMWQLRFCDDRVSAGFAIGQPADTPKPNADEIWRQRLDRFPFLRQQFAAAKIVAPASGLQTTSRMQRLTSLAAGPGWAALPNTAGFIDPLHSTGLAHTMFGVRRLVEILLQTGTSNQLLAELENYSSTLIDELRLVDQLVEGCYAGLPSFRLWSAWCMLYFAAVTSMEQSPGGGVAAFLHADDPRFRTVVGEARGELQRAIDAGRGPAACERFEAWLRQAIAPWNRVGLLESECDGMYARTAKPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXD5</accession>
    <name>A0A518IXD5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF1080 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_37640</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010496">
        <property type="entry name" value="3-keto-disaccharide_hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06439">
        <property type="entry name" value="DUF1080"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022139584" description="DUF1080 domain-containing protein" evidence="2">
        <location>
            <begin position="30"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1080" evidence="3">
        <location>
            <begin position="172"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF06439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV57750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="372" mass="40626" checksum="AD814714DDFA8AFC" modified="2019-10-16" version="1" precursor="true">MPSTDLSTALPRLLLFLGLSLSLIATATAQDAADKPAAAATEVKEKAEASKTPAEAAEKESKPADSKPAEAKTEEKPEAKPEVKPEAKQEKKTDEKPAKPKKEAEPAKPAAEEPKAEAKPEPKKITSLGYSNTPFIRGQRWKVHDMNRPRPRAIVPGNASTYDKPGTAPSDAIVLFDGNNLDNWGQLLPEDPGSIYQPLWSVADGAVTVVPETGHLRTLDTFADCQLHIEWASPEDVQGASQERGDSGVLLMGKYEVQILDSFNNRTFADGQAGAIFGQHPPMVNASRPSGQWQVYDIVFEAPTFKDGKLESPAYMTVIHNGILLHHRRELVGSVKDKELQPYSEDQPAGPIVLQNHGTPVRYRNIWIRPLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXI0</accession>
    <name>A0A518IXI0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Global nitrogen regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ntcA</name>
        <name evidence="4" type="ORF">Mal33_38140</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012318">
        <property type="entry name" value="HTH_CRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13545">
        <property type="entry name" value="HTH_Crp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00034">
        <property type="entry name" value="HTHCRP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00419">
        <property type="entry name" value="HTH_CRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="SSF51206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51063">
        <property type="entry name" value="HTH_CRP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="2">
        <location>
            <begin position="13"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="HTH crp-type" evidence="3">
        <location>
            <begin position="147"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV57799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="241" mass="27113" checksum="4F49069C7C5A07DA" modified="2019-10-16" version="1" precursor="true">MAEQVWHLKSCELFANLATDQIRRLEMHSRVRSFTARSLVYLPYQAADSVFLLTRGMVKVCHSTPDGKQSTLAFIEPGELFGELALFDPSQRDEFVEVVTAATVVMIPADQLIQLMSEANAFAVGITKLVGLRRQRIQRRLRNLLFQSNRDRLTHLLLELAEQFGVPAEQGVRLRIKLSHQELANLIGSTRESVTIVLGQLKAEGLIESGRRQIVLLRPQQMAEGVGQSYRQTPPQGLPTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IY12</accession>
    <name>A0A518IY12_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_39910</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011453">
        <property type="entry name" value="DUF1559"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07596">
        <property type="entry name" value="SBP_bac_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="30"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="365" mass="38606" checksum="8CA855BBE2A9DA94" modified="2019-10-16" version="1">MASSQLLLPSSQTPAARSSSDPSEKRRRGFTLVELLVVIAIIGILVGLLLPAVQAAREAARRMQCGNNMKQLGLALHNYASTYNEAFPNNGWSYPGGYPNDFSPFAKLLPFIEQENLQDLIDFDLYMGHPALADLPLALQAAAGTRVPTFECPSDVGADVHSLTMPSGTTIQIAGTSYAMNQGSGLDGVFHPGNGTPSDGLCWIGAKIRFRDIVDGTSNTIVFAETTIGTGIDIASPTPVQDPRAYRASATSGVNAAMADAADAGGLAGVQSFIASWKGDRNHYWLRGSVPNGPVMNGRLTPNSEVPDMTYGSSKMTAARSYHPGIAVLSLADGSVRNASDTIDRAVWHASWTRHGGEVKTVASQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IY54</accession>
    <name>A0A518IY54_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_40340</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="80" mass="8497" checksum="250677F3B5FF4E92" modified="2019-10-16" version="1">MSSIPVELPEHLMSFVSRGAEQAGYSTAGEFIAALVAAASKEQSETEQALMAGISSGDAKPWTDAEWKAIKERVIAKSVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IY66</accession>
    <name>A0A518IY66_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_40470</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="216" mass="21886" checksum="92D780AC19A1EC9B" modified="2019-10-16" version="1">MDNAIHLMGEHATTCADFSVRAQVQSTPTDPTNPLMGRVSLTAEGPNDDGNVCLQANGRVTSQVDECRIDVLSDGIVVDSGNTGNIGLRAGAAPCMQRIDVEGNGGSIVLENGQIEGSPKIDIGEDSITLSVGTNKITISATGIKVEGLEITIEGTTSAEMKAPSVSVDASADATIKGAASTEVSSSGTMVVKGTASTEVSASGTMTLKGAMVMIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYA1</accession>
    <name>A0A518IYA1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_40820</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010869">
        <property type="entry name" value="DUF1501"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07394">
        <property type="entry name" value="DUF1501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="435" mass="47156" checksum="3DB85D7A36C10D8F" modified="2019-10-16" version="1">MFKCQGNAISRRGFVAAGALGGLGLSLPQLLSMQQARADMKHYDFIEAKAQSVIHIFLPGGIAQQESFDPKPYSPIEFRGEMKTVKTNTGEVFSESMKEVAGIADKVCVIRSMTHGEAAHERGTHNMFTGYKPSPALVFPSFGSVVSHEYGPRNNLPPYVCIPNQPNEFAGSGYLSSSYGPFALGADPASKNFKVRDLDLYKGADGERFARRQSALEVVNQKFGSLTSADNVGAMSTFYDRAYSLLGSEEAKTAFDLDKEDAKMKAAYGENTAGMRMLMARRLVEAGCRLVTLTYGGWDMHSNLTAGMKRSTPPLDHALTQLIKDLEQRGMLDSTLVMVTTEFGRTPKINKDAGRDHYPKVFSVMLAGGGIKGGTVYGASNATASEPEFDPVTPEDLATTMYHQLGIVADKELMAPGDRPMEIVDGGKVIKDILA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYD5</accession>
    <name>A0A518IYD5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ethanolamine utilization protein EutM</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">eutM</name>
        <name evidence="3" type="ORF">Mal33_41180</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031469">
        <property type="term" value="C:bacterial microcompartment"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000249">
        <property type="entry name" value="BMC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037233">
        <property type="entry name" value="CcmK-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044872">
        <property type="entry name" value="CcmK/CsoS1_BMC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00936">
        <property type="entry name" value="BMC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00877">
        <property type="entry name" value="BMC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143414">
        <property type="entry name" value="SSF143414"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51930">
        <property type="entry name" value="BMC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1283">Bacterial microcompartment</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BMC" evidence="2">
        <location>
            <begin position="4"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00024446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="90" mass="9020" checksum="842A2E3783AEF586" modified="2019-10-16" version="1">MNQALGLVETKGLLALIEATDAMAKAANVEITKRIDIGGAFCTTVVTGDVGSVRAAVEAGAAAAAQVGELVGSHVIARPSEGLVEAFINK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYE3</accession>
    <name>A0A518IYE3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_41230</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="201" mass="21362" checksum="9D8771FD738D0E70" modified="2019-10-16" version="1">MTSTPLDLEAIVRRIVGEVVAGAVAPKSQPVASANTRLCLIDRPVIALADVEKRLDGKSEIAVAPRAVITPAVKDLLRAQSIAIVREEKQNTMRTPIAAPAAILVADVDCSNRCAAFAKQLGIRTRRGVQIVVAEEARIVLADLPQRVVCDLCRSGAEAVQVGSLSEVQAVAAAMQPDVWVLDMTRLNVIAATNLATRLTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYI7</accession>
    <name>A0A518IYI7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Amidohydro-rel domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_41640</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="1">
        <location>
            <begin position="389"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="474" mass="50952" checksum="5238F070D5793921" modified="2019-10-16" version="1">MSKQYQNLIRSLFPAATKNSEKKASEPASQLNICRRSFLIRSVLATLFGSAVVAGTNVNANDQIPGAAQTTPIALVGGVVHTVDAKTLNNATVVFEKGKITQVGKKVVLPAKCRSIDVSGKHIYPGLMESMSNVGLSEIGSVRATVDTDEVGDENPNLRPWVAVNADSELIPVARAGGVLLASIAPKRGNIRGQSAVIQLDGWTYKDMLLRGDTGMLVSWRSYDSRRGSSTDRAKERDERLKGLSDRLETAARYAIARAARPDWTPVDLRFEALIPVLEGESPMIIDADDRREIEAAVAFCVARGIRPIIYGGYDAPECAPLLKKYDVPVIVHSTYRLPLRRDDPYDHPYTLPSRISKAGIRFAIGGPGSGSPGGGAAARNLPYHAAVAVSYGLPADQAIHAITLAPAEIMGVADRVGSITVGKDATLIVVDGDILQTESNVTDAYIGGAKVDLGSKHKTLADKYRRKYNQRSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYL1</accession>
    <name>A0A518IYL1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">VWA domain containing CoxE-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_41930</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008912">
        <property type="entry name" value="Uncharacterised_CoxE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05762">
        <property type="entry name" value="VWA_CoxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="401" mass="43851" checksum="12D107A65452EEE1" modified="2019-10-16" version="1">MATPKPIAPEQLGRWRLILGASSQDQLNQYGGGDLSLDADQQLMDEALAAIYDQTQEGSDSSGKRSAGSGGSSPRLAKWLGDIRTYFSEDVVAVIQQDAIDRKGMRELLLEPELLKNVQPNVQLVGTLLSLGGQIPERTKETARMVVRAVADKIKLTLEQRIRQAVQGALNRNEHSPIPHANSIDWKWTIGRNLKNYNAQLGRLIPERVYFYSRAQRTNNWTVIVDMDQSGSMADSVVYGAVTGSIFASLPALKTHVVAFDTEVVDLTETCGDDPVDMLFGVQLGGGTDINKSVAYCEQFITEPSETLFILLTDLFEGGNQAQLVRRLGEMVESGVRVLCLLALSDSGTPCFDEALARRLSALGIPCFACTPDRLPELVEGTLRGQDLQSLATRIKSDDSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYQ1</accession>
    <name>A0A518IYQ1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_42150</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022095246" evidence="2">
        <location>
            <begin position="23"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="357"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="363"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="629" mass="69575" checksum="D186E4C22255E9DA" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYQ9</accession>
    <name>A0A518IYQ9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_42310</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="81" mass="9226" checksum="5EAB8C66C72DAE19" modified="2019-10-16" version="1">MNLQIDLVSAIFLLATGNYQSPTHAIRLIALPNLRFRKLASILAVDSPHLQKHLYNNKVNTRWACSYYARSSCWSQAESPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ03</accession>
    <name>A0A518IZ03_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_43270</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="205" mass="22884" checksum="D876CCB4F4C3D160" modified="2019-10-16" version="1" precursor="true">MSRIPTCPRRQKKELEYQRYFPVQLPSPHGWMLRLINAPPSVRSPDERPKTLSKLNALANTDTDTHIAASNGRHCLTSAAAGPPLTSRLRAAIRPLSIPRRWTHTPMLPSNACLRFPCTAHLKATTRPHRLLLIFAAEIDDTLCHLQPHVARGHYASHSLPTRFAVPSGVAAKRLLFRNESFAIPRIVGVFADESNAHRSFDPST</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZV3</accession>
    <name>A0A518IZV3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_46360</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="61" mass="6580" checksum="CDC9B72A08AAA445" modified="2019-10-16" version="1">MKLSDFYNEVSTRVDTDKTAINAAVTKRVLSEAFLVLAAMDAADVTDTISKGLNNAKKKMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZX9</accession>
    <name>A0A518IZX9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_46780</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016195">
        <property type="entry name" value="Pol/histidinol_Pase-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89550">
        <property type="entry name" value="SSF89550"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022113497" evidence="2">
        <location>
            <begin position="29"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="399"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="426" mass="47671" checksum="A4BEA7F4EDA46024" modified="2019-10-16" version="1" precursor="true">MPNSFCRKLRPLLATCLLISCFSLTGVAADPVPAEPALRWWKGNMHTHSLWSDGDDFPEMIAEWYRTQDYNFLVISDHNVLGLGQRWMKQTAIAKRGGQSALAKYKARFGGSWVETRGEGDDLEVRLKPFDEFRYLLENRGQFILIPGEEVSDRAAGKPIHMNASNVGEVLKPMGGATPVEAMSNNLRAVEEQAKRLGREILMHLNHPNFGWAITAEEMAQVTSEQFFEVYNGHPGVNHLGDATRPSIEHMWDIANTMRLTVLEASPLLGLATDDSHDYHDGMLSRSISGRGWVMVRSEYLTPEHLIQALRRGDFYASSGVSLEEVTFDPESRTLTVQIDPEADATYTTQFIGTRIAPDADKTLMPAKEKIGIEFAKQEGNVATYTMQPGDLYVRATVTSSEGADRPSFKDQKKQAWTQPVGYETR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0C5</accession>
    <name>A0A518J0C5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_48160</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="98" mass="10949" checksum="D09CC17A04DCC363" modified="2019-10-16" version="1">MKFQTGIVVGGLIAALLLTNPSKEDHVRKLAAERLAPYTEEGSDSPLVRIGSAFAESFSDSVIDYHNYWLFSTTTSLDSDQRLTLGFLRFVHVEKRTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0F7</accession>
    <name>A0A518J0F7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Flavohemoprotein</fullName>
            <ecNumber evidence="7">1.14.12.17</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">hmp_2</name>
        <name evidence="7" type="ORF">Mal33_48480</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.14.12.17" evidence="7"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008941">
        <property type="term" value="F:nitric oxide dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006058">
        <property type="entry name" value="2Fe2S_fd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008333">
        <property type="entry name" value="Cbr1-like_FAD-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00970">
        <property type="entry name" value="FAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="SSF52343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00197">
        <property type="entry name" value="2FE2S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="6">
        <location>
            <begin position="62"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="5">
        <location>
            <begin position="315"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV58823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="400" mass="43104" checksum="98102185D6C3332D" modified="2019-10-16" version="1">MVIGIITILAVIAQLIGLATGTATAQQRLRAQWREWCSRSNSQLTNQVVAADRSRPFSPAWSGWRSLRVIHTEMVSADCKTFVFADPDGSPMPSFVPGQFLMVGRVDEPGAAPVAARCYSLSDAPSPSHLQITVKRIDNGQVSAWLHDTVSVGDTVQTRAPGGRFVLDIERTDLVVGIAAGVGITPMASMAKYLTKMQPGRSVIVFLSARDAAHCPMVDELRELERNNAFFTLVVLQSRPAPGDRFDLKGRLTIDIISRVVGQPIGSYYLCGPPEFMTHLSDALIQWGVPEDSVSFESFGGPKPQDTVVEGEASKPIPVEFRRSGKKLAFNAADGNLLDAAEKAGVQMDADCRAGACGTCLKKLIKGKVQYDQAPSFSPIADDECLPCVGRPSEETVVDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0N2</accession>
    <name>A0A518J0N2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATP-dependent helicase/deoxyribonuclease subunit B</fullName>
            <ecNumber evidence="2">3.6.4.12</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rexB</name>
        <name evidence="2" type="ORF">Mal33_49250</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.6.4.12" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011604">
        <property type="entry name" value="PDDEXK-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038726">
        <property type="entry name" value="PDDEXK_AddAB-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12705">
        <property type="entry name" value="PDDEXK_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDDEXK_1" evidence="1">
        <location>
            <begin position="666"/>
            <end position="932"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="953" mass="105004" checksum="82B7F7B95B729E67" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0N5</accession>
    <name>A0A518J0N5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Flagellar motor switch protein FliN</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">fliN_2</name>
        <name evidence="3" type="ORF">Mal33_49190</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FliN/MopA/SpaO family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009425">
        <property type="term" value="C:bacterial-type flagellum basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003774">
        <property type="term" value="F:cytoskeletal motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001543">
        <property type="entry name" value="FliN-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001172">
        <property type="entry name" value="FliN_T3SS_HrcQb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036429">
        <property type="entry name" value="SpoA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01052">
        <property type="entry name" value="FliMN_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00956">
        <property type="entry name" value="FLGMOTORFLIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101801">
        <property type="entry name" value="SSF101801"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0966">Cell projection</keyword>
    <keyword evidence="3" id="KW-0969">Cilium</keyword>
    <keyword evidence="3" id="KW-0282">Flagellum</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FliMN_C" evidence="2">
        <location>
            <begin position="11"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="89" mass="9759" checksum="B21A5A5CAA40AADC" modified="2019-10-16" version="1">MPTANLSFQQRVLGIETEVSVVLATKKIQLDDVLNLTTGAMLSFEKGYDEPLDLMIGKEPIASGEVVKLGDKFGLRVRDLAHEKTGQDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0N9</accession>
    <name>A0A518J0N9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Soluble aldose sugar dehydrogenase YliI</fullName>
            <ecNumber evidence="4">1.1.5.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">yliI_2</name>
        <name evidence="4" type="ORF">Mal33_49360</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.5.-" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010496">
        <property type="entry name" value="3-keto-disaccharide_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012938">
        <property type="entry name" value="Glc/Sorbosone_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011041">
        <property type="entry name" value="Quinoprot_gluc/sorb_DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06439">
        <property type="entry name" value="DUF1080"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07995">
        <property type="entry name" value="GSDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50952">
        <property type="entry name" value="SSF50952"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021709434" evidence="1">
        <location>
            <begin position="30"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1080" evidence="2">
        <location>
            <begin position="44"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="domain" description="GSDH" evidence="3">
        <location>
            <begin position="302"/>
            <end position="633"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV58911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="643" mass="71832" checksum="A81C7D93D3D2E25C" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J107</accession>
    <name>A0A518J107_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_50450</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="196" mass="22132" checksum="476E33015925D918" modified="2019-10-16" version="1">MHPSCRSGVPEVKVTWRQPGDFGRYPTESSRRIMPRRRDLIAYATATLFGIPYCATVRADTATEEPLFLHIYSNTRGSTYDQDKKNRNEAPAFNSQWVRVVSLLVVPKTRIYVRLPGGRDPDITVDGNVARKSNGQLVASLNVAWDDSYITERHSIAGPLEIKKPHPSSTIHCRYIFSRSKDAYDALDHTLAKDGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1J5</accession>
    <name>A0A518J1J5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_52350</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="463" mass="51711" checksum="D8978635F64B0552" modified="2019-10-16" version="1">MSIAMNLRHSAWIVVLLLVGSETPLLAIKPCRIEIVEKSNGWPVPLVELTTTHGVCFVSDNAGVIAFDLPELLATETWFHVRGHGYSVPPDVFSYRGVRLRPQPGATLTVEVQRQLPAKRLGRITGGGLFSECQKLGTELDWRDQGILGCDSVQTALHDGRLHWGWGDTTLPQHPLGRFHTIGATTEPQPLQTFEPPIRLRYDYVVDETQTPRNIAVMPGDGPTWLGGYVSLPNREGQPQLVATYSKIVPPLAVYEIGFCTWDETSANFEPTNVLWRRSDATPDPPTVPHGHSTRWTDPAGGDWVLFGDPFPTLKIPATYEALLDRSQWQSITPQTTVATRAGESEKQVRPHRGSIAWNEYRKKWVAIFTQHGGQTSLLGEIWYAEADTPTGPWTDAVHVVTHDDYTFYNPKLHPEFTAPGSAMLLFEATYTKTFSGTKQGTPRHNYNQILYRLDLQDIATTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J220</accession>
    <name>A0A518J220_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_53990</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008969">
        <property type="entry name" value="CarboxyPept-like_regulatory"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49464">
        <property type="entry name" value="SSF49464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022145065" evidence="1">
        <location>
            <begin position="28"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="183" mass="19290" checksum="2400F93B43BDEA2C" modified="2019-10-16" version="1" precursor="true">MFQSIQAKRAIAAVVCAAVCMQQAVFAAQPQFTMVEGVKVYSGIQDLALDQQGNLNGSVVDVDGKPVQGATVVIGQQTEHVTTVKTNDEGVYSVKGLKPGVYQVVSFAGLRTYRVWNADSAPEGSVKGAIGVTDTKTFRGQCDERGGDESLCLRLLKSPLVWTAVIAAAIAIPLALDDDDDAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J236</accession>
    <name>A0A518J236_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_54370</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="167" mass="18485" checksum="D06AE36D0D68997A" modified="2019-10-16" version="1">MNYDTKPADRESDTERPLPCNRGYQEPLHRCESDRLFRARLSETLVGGKQKLDRHLAHQVDQGILSSLAVGERLKSRIDQLLQAIRSSGDANSPLLDSQRWSDREAGEIDALENTLLQTSAAIAELADGLTKQEATSRDAIGRMSGLIDELAAGFDTRLQRIETIGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J2A0</accession>
    <name>A0A518J2A0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Xylose isomerase-like TIM barrel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_54970</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013022">
        <property type="entry name" value="Xyl_isomerase-like_TIM-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01261">
        <property type="entry name" value="AP_endonuc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="SSF51658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AP_endonuc_2" evidence="1">
        <location>
            <begin position="54"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="288" mass="31923" checksum="FF588AE65BAF98EC" modified="2019-10-16" version="1">MKRRDFLTTTAIGTAGLLASRPQLVAAAEKSDGMKLGLVTYNWGRDWDVPTLIRNCEETGFRGVELRSTHKHGVEISLDAGQRREVAKQFADSDVELVGLGSACEYHSPDPAIVKKNIDETKQFIKLCKDVGGSGVKVRPNGIPKNVPIEKTLTQIGMSLREVAKFGAEHGVVIRLEVHGRDGSSELPNIHRMMEVADHPNAVVCWNCNSTDLAGQGLQHNFDLVKEKIDVVHIHDLRNNNYPWEQIFAMLKQSQFAGWTLLEDGKVPDDIVAAMHENRKVWDGLVAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J2B2</accession>
    <name>A0A518J2B2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_55050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022097619" evidence="1">
        <location>
            <begin position="33"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="422" mass="47296" checksum="2AC4F9E46FBA1300" modified="2019-10-16" version="1" precursor="true">MTDQMLPRRQFIAQQASLALLGLGALPLAAAAAESEFPVRKITSGPKHHWFGYYDKLQFDPSNRYVLGMQVDFEHRSPTADDTIQIGMVDLEDGDRWIELGETKAWSWQQGCMLQWLPGSDSEIIWNDRSGDRFVSRIMDVHTKKTRTIPYPVYSVSPTGKTAVTADFRRINDVRPGYGYAGLPDPNAEVLAPDDSGIQQVDLVTGEAKTIITIADIARTGAIPKPEFGIKHYFNHLLFSPDGSRFIALHRWRYPNGSRLTRMITANVDGSDLRIVCGNGYTSHFIWRDNTHILAQSRHFDGNDNWANFLFEDVDGGGDVREVGRGVLDGGGHLSYLPGNKWILNDTYPKGKSRLQTPHLFEVATGRRIDLGGFHLPPIYKGEWRVDTHPRLSRDGKFVCIDTPAEGEGRQLHLIDISKVVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J2C5</accession>
    <name>A0A518J2C5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative deoxyribonuclease YcfH</fullName>
            <ecNumber evidence="1">3.1.21.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ycfH</name>
        <name evidence="1" type="ORF">Mal33_55160</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.21.-" evidence="1"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004536">
        <property type="term" value="F:deoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01310">
        <property type="entry name" value="TatD_DNAse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018228">
        <property type="entry name" value="DNase_TatD-rel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015991">
        <property type="entry name" value="Hydrolase_TatD-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001130">
        <property type="entry name" value="TatD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01026">
        <property type="entry name" value="TatD_DNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005902">
        <property type="entry name" value="DNase_TatD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00010">
        <property type="entry name" value="TIGR00010"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01137">
        <property type="entry name" value="TATD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01091">
        <property type="entry name" value="TATD_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="262" mass="29318" checksum="D780395C1A3239D2" modified="2019-10-16" version="1">MKLFDTHAHLDNQRYDDDRDALMQRSRDAGVVCTLAMGTTAASSRKCIEIADRYPDVYAAVGIQPTYVGKPDAGDWDEIVELAKHPRVKAIGETGLDCYWDDNAPLPLQQTLFQQHIELSRQTGLPFIVHMRNSEAEVLQVLQEAGKQGPVNGIMHSFTGDWELAQKCLDLGMDISFAGMVTFKKSQDLRDVAAKIPADRILIETDSPYLTPHPFRSKRPNEPWYVQHTAECLAEARGVSVQQFADQTTQNACRRFAIALDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ILV0</accession>
    <name>A0A518ILV0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_00170</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="153" mass="16653" checksum="7B11909BCB124C0B" modified="2019-10-16" version="1">MHRKLNRCAVSRRRGAYTLEVAITMLIFLGALLAMLEFALVSLRYNALGESARRIARVVIVRGEQAAPEQSVLGPAAYVGTADDSSDIAAAARQLLVTMPLEDVDIRVEWLDADTREGDRVSIQLSYLHNPILPGLLGSAKTLSATTVTRIVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IM53</accession>
    <name>A0A518IM53_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pseudouridine synthase</fullName>
            <ecNumber evidence="3">5.4.99.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Mal33_01070</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Responsible for synthesis of pseudouridine from uracil.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a uridine in RNA = a pseudouridine in RNA</text>
            <dbReference type="Rhea" id="RHEA:48348"/>
            <dbReference type="Rhea" id="RHEA-COMP:12068"/>
            <dbReference type="Rhea" id="RHEA-COMP:12069"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the pseudouridine synthase RluA family.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.-" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120159">
        <property type="term" value="F:rRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000455">
        <property type="term" value="P:enzyme-directed rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd02869">
        <property type="entry name" value="PseudoU_synth_RluA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006225">
        <property type="entry name" value="PsdUridine_synth_RluC/D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006224">
        <property type="entry name" value="PsdUridine_synth_RluC/D_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00005">
        <property type="entry name" value="rluA_subfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01129">
        <property type="entry name" value="PSI_RLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S4" evidence="6">
        <location>
            <begin position="72"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="PseudoU_synth_2" evidence="5">
        <location>
            <begin position="146"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="35"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR606225-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV54161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="391" mass="44083" checksum="D68D8D8942DADD5C" modified="2019-10-16" version="1">MRYNDAPRAARPLAPLPQFDSNLHQKTALNDHSTDEEPVDEELLDEATSDDQESAAETTYRSIHVPESAQGERIDMYLTQVLDGVSRNQMRMLVHEGGAQVDGRTVRPSFRLRPNQQIRFRMPEPPEDGTIPEPMSLDIVFEDDGMVVVNKPPGMVVHPARGHWSGTLTSGLAYHFQSLSDIGGPTRPGIVHRLDRDTSGVIVVAKTNAVHMNLAAQFADRTVKKQYVAVACGVLSRDRDQIDRPIGRHPYQREKMAIRANHATSKEATTFYEVIERFRGFTYVRLFPKTGRTHQLRVHLDHLRHPILCDKLYGGRSRITADDLAGNYHPQPSAQRETIEPLLTRQALHAQRLELDHPQSGKRMVFEAPVPDDIEAVLKCLRSLNPSENRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IM58</accession>
    <name>A0A518IM58_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Multidrug resistance protein MdtC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">mdtC_1</name>
        <name evidence="3" type="ORF">Mal33_01240</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <location>
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        <source>
            <dbReference type="PROSITE" id="PS50156"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="QDV54176.1"/>
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    </evidence>
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        <source>
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        </source>
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    <sequence length="1091" mass="119399" checksum="A259A015D09B73E5" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IM69</accession>
    <name>A0A518IM69_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
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            <end position="38"/>
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        <location>
            <begin position="50"/>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="QDV54188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="380" mass="41612" checksum="A080FEC7896A5986" modified="2019-10-16" version="1">MYRHNFSLCGEMQRRQLLLSLVYTLDLFFCFVEELHVSRKNVGVTDSRTGFTLVELLVVIAIIGILVGLLLPAVQAAREAARRMQCSNNLKQLGLALHNYHDTYKVFPVASIITPDTDRPASWLVRVWPFMEQNAAFDQCTFAGSDWTGQGFDRNWRVTTNLSIPTLNCPSNPMDALYTQTSSAASQADGCPETVTYQITDYVGVGGTCNGGKTHWYGCHGRNDYSGIFVAIDAINTSNVRFASVTDGTSNTLAVGEQSNFIRIDDGAGNIEQVDLRDNTWKGGGWSGSEGGEADKGYWKGHSSFRVGINYSPTGRNSPHGIGDYWYGRPGHHTIFTSAHPGGAQFTLGDGSVRFISENINFTTLSNLGNRSDGNVVGDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IM81</accession>
    <name>A0A518IM81_9BACT</name>
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        <submittedName>
            <fullName evidence="7">Inner membrane protein YbjJ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ybjJ</name>
        <name evidence="7" type="ORF">Mal33_01400</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
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        <lineage>
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            <taxon>Planctomycetia</taxon>
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        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="MFS_dom"/>
    </dbReference>
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        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
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        </location>
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        </location>
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        </location>
    </feature>
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        </location>
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        </location>
    </feature>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
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            <end position="307"/>
        </location>
    </feature>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="376"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="22"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV54191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="414" mass="43024" checksum="F096A288C2C19E5D" modified="2019-10-16" version="1">MNNIAVPQWIVRNDSGNPLTASLWAVRGLFFLNGFLYATWATRIPAIQSQFQLSHAALGVALMMVALGAVVAMPTAGWLCSRWGSRRVVAISLLLYIAGLPLVALMPSLTALFIALLLFGVGHGMLDVSMNVQAVEVERRWQRPINSSIHALWSVGGLSGAIAGSVIGLWGLAAGLHFALVSAILSLAIVPIVTRLLIESPTAASDARDKEPQVPSPPRGRNRALILLGAIAFCIMAGEGAMADWSAVLLNQVLGVSEGLAATGYATFAITMAAGRFAGDRLSMRLGPMNQVRISGLVALAGLLIVVTSSHLVLALLGFAMIGGGFATIVPAVFSACGRLDNIPAGVALATVSTIGYFGFLLGPPLIGFVAELLSLRIALGCLSVTTLASVLLATTLAPRATATDTSQHDRCAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMB9</accession>
    <name>A0A518IMB9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Thiamine-phosphate synthase</fullName>
            <shortName evidence="8">TP synthase</shortName>
            <shortName evidence="8">TPS</shortName>
            <ecNumber evidence="8">2.5.1.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Thiamine-phosphate pyrophosphorylase</fullName>
            <shortName evidence="8">TMP pyrophosphorylase</shortName>
            <shortName evidence="8">TMP-PPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 12" type="primary">thiE</name>
        <name evidence="12" type="ORF">Mal33_01740</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8 9">
            <text>2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate + 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + 2 H(+) = CO2 + diphosphate + thiamine phosphate</text>
            <dbReference type="Rhea" id="RHEA:47848"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37575"/>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
            <dbReference type="ChEBI" id="CHEBI:62890"/>
            <dbReference type="EC" id="2.5.1.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 8 9">
            <text>2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate + 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + 2 H(+) = CO2 + diphosphate + thiamine phosphate</text>
            <dbReference type="Rhea" id="RHEA:47844"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37575"/>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
            <dbReference type="ChEBI" id="CHEBI:62899"/>
            <dbReference type="EC" id="2.5.1.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 8 9">
            <text>4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + 4-methyl-5-(2-phosphooxyethyl)-thiazole + H(+) = diphosphate + thiamine phosphate</text>
            <dbReference type="Rhea" id="RHEA:22328"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37575"/>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
            <dbReference type="ChEBI" id="CHEBI:58296"/>
            <dbReference type="EC" id="2.5.1.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="8">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 8">Cofactor biosynthesis; thiamine diphosphate biosynthesis; thiamine phosphate from 4-amino-2-methyl-5-diphosphomethylpyrimidine and 4-methyl-5-(2-phosphoethyl)-thiazole: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8 9">Belongs to the thiamine-phosphate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.3" evidence="8"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00060">
        <property type="reaction ID" value="UER00141"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004789">
        <property type="term" value="F:thiamine-phosphate diphosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009229">
        <property type="term" value="P:thiamine diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00564">
        <property type="entry name" value="TMP_TenI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00097">
        <property type="entry name" value="TMP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036206">
        <property type="entry name" value="ThiamineP_synth_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022998">
        <property type="entry name" value="ThiamineP_synth_TenI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041397">
        <property type="entry name" value="ThiD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034291">
        <property type="entry name" value="TMP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016229">
        <property type="entry name" value="TMP_synthase_cyanobac_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17792">
        <property type="entry name" value="ThiD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02581">
        <property type="entry name" value="TMP-TENI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000512">
        <property type="entry name" value="TMP_PPase_Cyanobac_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51391">
        <property type="entry name" value="SSF51391"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00693">
        <property type="entry name" value="thiE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8 9" id="KW-0784">Thiamine biosynthesis</keyword>
    <keyword evidence="5 8 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ThiD2" evidence="11">
        <location>
            <begin position="13"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="TMP-TENI" evidence="10">
        <location>
            <begin position="152"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="HMP-PP binding" evidence="8">
        <location>
            <begin position="181"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="THZ-P binding" evidence="8">
        <location>
            <begin position="278"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="213"/>
        </location>
        <ligand>
            <name>4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine</name>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="214"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="233"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="252"/>
        </location>
        <ligand>
            <name>4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine</name>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="281"/>
        </location>
        <ligand>
            <name>4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine</name>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="308"/>
        </location>
        <ligand>
            <name>2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:62899"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF17792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QDV54224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="357" mass="38304" checksum="107A8F358E6AE1F8" modified="2019-10-16" version="1">MDGKESTASGVWRILDASLNRASEGLRTIEEYARFVLGDPQLSEQLKQLRHQTATAAEGLPRSQLLAARDTPGDVGTAIETPTETERVDALAVAIAAAARVQQSLRCLEEYGKIVDSGIGRAFEACRYRSYTLFATLEQLSQRRDRLADCQLYVLVDGGDSIEAMTATIAELAKAGADLIQLRDKRLNDRELYEHAAAAAATLRPSRCLFIVNDRPDIAAAVHADGVHVGQDELPATVVRQIIGPERLLGVSTHCVAQVEQAVSDGADYIGCGPTFPSGTKSFEAFPGTDFLRDAAATTTLPSFAIGGIGAENLEYVLDAGFSRVAVAGAITRSESPAAMVAELKQRLLRQDESTNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMJ6</accession>
    <name>A0A518IMJ6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase (GNAT) family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_02570</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016890">
        <property type="entry name" value="UCP028520"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028520">
        <property type="entry name" value="UCP028520"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="4"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="170" mass="18948" checksum="32B93ED84938DA87" modified="2019-10-16" version="1">MNRPILREMTPDDAARVIALNEAAVDVTSPIDADRFAELYELSSVRLVAETNCEVVGFVLAMTDACGYDNGNYRWFAKRLKNFLYIDRIVVSATCRGLGLGRLIYSRIYELARQTGSVQVCAEMDLNPPNNASLDFHSKAGFIQLGTRSLESGKQVSMQTRFLPCEPEKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMK6</accession>
    <name>A0A518IMK6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Carrier domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_02850</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="2">
        <location>
            <begin position="7"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="1">
        <location>
            <position position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="91" mass="10366" checksum="5E6B354AF9EB09AB" modified="2019-10-16" version="1">MTSKTRPEILSELQEILSDFQGQTYDAPIDEQTMFFQDLGFASIDAVVLGETLEEHFQTKLDFNPFLSELAAKQVKDLQVGELVDFLHRSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMM8</accession>
    <name>A0A518IMM8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA mismatch repair protein MutL</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 8" type="primary">mutL</name>
        <name evidence="8" type="ORF">Mal33_02920</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the DNA mismatch repair MutL/HexB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032300">
        <property type="term" value="C:mismatch repair complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1540.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00149">
        <property type="entry name" value="DNA_mis_repair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014762">
        <property type="entry name" value="DNA_mismatch_repair_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020667">
        <property type="entry name" value="DNA_mismatch_repair_MutL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002099">
        <property type="entry name" value="DNA_mismatch_repair_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013507">
        <property type="entry name" value="DNA_mismatch_S5_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038973">
        <property type="entry name" value="MutL/Mlh/Pms"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014790">
        <property type="entry name" value="MutL_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042120">
        <property type="entry name" value="MutL_C_dimsub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042121">
        <property type="entry name" value="MutL_C_regsub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037198">
        <property type="entry name" value="MutL_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10073">
        <property type="entry name" value="PTHR10073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01119">
        <property type="entry name" value="DNA_mis_repair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08676">
        <property type="entry name" value="MutL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01340">
        <property type="entry name" value="DNA_mis_repair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00853">
        <property type="entry name" value="MutL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118116">
        <property type="entry name" value="SSF118116"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00585">
        <property type="entry name" value="mutl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00058">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3 4" id="KW-0234">DNA repair</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA_mis_repair" evidence="7">
        <location>
            <begin position="209"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="domain" description="MutL_C" evidence="6">
        <location>
            <begin position="466"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="338"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="363"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV54339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="663" mass="72469" checksum="6AFFF3E84FD1BFDB" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMN3</accession>
    <name>A0A518IMN3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Biopolymer transport protein ExbD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">exbD_1</name>
        <name evidence="8" type="ORF">Mal33_03000</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the ExbD/TolR family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003400">
        <property type="entry name" value="ExbD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30558">
        <property type="entry name" value="PTHR30558"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02472">
        <property type="entry name" value="ExbD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV54347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="141" mass="15392" checksum="3ABE8F2C70AE270C" modified="2019-10-16" version="1">MAVQLKKSQATSTLSLTPLIDVVFLLLIFFLVASRFAQEDRRIPIELPSATSATPMTEQPKEIVVDIDSEGALVLNGNTVTADELETELVRGVASNPVHQSVVIRADRRVQFQSVVTVMDLCNRTGVADYTVTTQEGPGEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMQ6</accession>
    <name>A0A518IMQ6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_03230</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="54" mass="6264" checksum="9D197870530516C4" modified="2019-10-16" version="1" precursor="true">MPRRLPLVEHRCKETLQGRRVLRIATGLTETDDARMLRLLKIRQFEGTSLCDAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IN96</accession>
    <name>A0A518IN96_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RNA pyrophosphohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_05280</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the Nudix hydrolase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020476">
        <property type="entry name" value="Nudix_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00502">
        <property type="entry name" value="NUDIXFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="3">
        <location>
            <begin position="1"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV54573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="140" mass="16585" checksum="419C9A6E35A01318" modified="2019-10-16" version="1">MIQAAGYLVFRNHPRRQFLLMRHADRWDLPKGHVDDGESILQTARRELREETGIRPKDFVHDENFLFQIEYRVIGRKSGKPRDKRVSIFLAELTTEIEIVPTEHPGFEWFDWSPPHQIQPQTIDPLLAYAEKFFDQSNRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INB5</accession>
    <name>A0A518INB5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase (GNAT) family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_05430</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="54"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="172" mass="19457" checksum="EB25F938D8F10ABC" modified="2019-10-16" version="1">MSGVRYPDGWRVELLDKSHNRKSFRCGQAQAESWLKKSALQSQKKHLSSTKVLLDADAHLVGYYTLATSQVDFSDLPAELARSLPQRRLPVAVLAWFGVASSFQRRGIGQRLLATALKDCLDASQTFSFIAVILDCVDESSKQFYQRFDFATLPGYPMRMYLPFITLQQMAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INH0</accession>
    <name>A0A518INH0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_05980</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="164"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="183" mass="21869" checksum="E7B52D0C626461BC" modified="2019-10-16" version="1">MDEVDQLMLNAQLRDELEPYIDESVSRIDVRRMPLSQENEFLASMLAWEQAPAIPISHWFEPALALPHPDELDRDELHDCLWNAIERLHSKRIILECTDHLTDRELYKIIFRDILPCREKKVDLPRNFLHWRCFDDGDNDTWLRFYATPNERWQWEQETGLTVPLAENPPYPRHMPTRPPQDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INL4</accession>
    <name>A0A518INL4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">LamGL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_06070</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006558">
        <property type="entry name" value="LamG-like"/>
    </dbReference>
    <dbReference type="SMART" id="SM00560">
        <property type="entry name" value="LamGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022104300" description="LamGL domain-containing protein" evidence="2">
        <location>
            <begin position="30"/>
            <end position="1105"/>
        </location>
    </feature>
    <feature type="domain" description="LamGL" evidence="3">
        <location>
            <begin position="116"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV54652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1105" mass="122055" checksum="02BE30A92994707B" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP48</accession>
    <name>A0A518IP48_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_08070</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022066635" evidence="2">
        <location>
            <begin position="23"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="419" mass="44184" checksum="593632C56F39573C" modified="2019-10-16" version="1" precursor="true">MNTKRKNLANLIATFAIGVATSATGLAQDNCPCPPTNCHPNTIISDGVTTLPTTPFPSANDEEGSSVVSPQPDVDSAPQSFANDVAMPSSRIASTGFSAAPAASAASAGGGGLDTPNMLGDLFLSTHSSGGSLIANPSQRVAGGDARFKVSDGISPVPTDRVFFNYRHFENALATEGNKDISVDRFLFGLEKTFLDKQASLELRVPFAHGLDSNNPTGNQTGTEFGNITLTSKFLLAQNGGDALTAGLAIVLPTGSNYTEGDDTAYNTAVHLLPYLGIRKFLTEDIFTLGYAALDFDLNGTEVYDAGAYADTVQDQNLLYLDWQLGAFLYTNDSGNLRSVASLFELHYTKTITDVDPAMGSAFGNHIDLLNLTAGLSFGLCNHLTTNVFAGVPLRREQTPDGLSATFDTEVGFQVILTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP67</accession>
    <name>A0A518IP67_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_08540</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008964">
        <property type="entry name" value="Invasin/intimin_cell_adhesion"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49373">
        <property type="entry name" value="SSF49373"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="179" mass="18816" checksum="5026DD73B9C59362" modified="2019-10-16" version="1">MVCLLIHSNGRRPHDTRFTNNFTTDTRLAIEDIRLNLQLRTSHRLKIPLPGLLIAGFLSAAIGCGGSSGEPLASVAGKVTQNGQPLSGAIVMFVPESGSGGPSGGETDANGDFQLKYSTGETGATIGKHRVVITIPGTEAPAPMGGETKPVKTEPSREFFKEAEVVDGENALTFEIAEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPU9</accession>
    <name>A0A518IPU9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Stage V sporulation protein K</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">spoVK</name>
        <name evidence="4" type="ORF">Mal33_10950</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CbxX/CfxQ family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041627">
        <property type="entry name" value="AAA_lid_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000641">
        <property type="entry name" value="CbxX/CfxQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17866">
        <property type="entry name" value="AAA_lid_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00819">
        <property type="entry name" value="CBXCFQXSUPER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="3">
        <location>
            <begin position="286"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="173"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="181"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="213"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV55126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="577" mass="63867" checksum="50327E805082681D" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQ26</accession>
    <name>A0A518IQ26_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_11610</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="9"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="194" mass="21824" checksum="7898BCBDB85A4A5F" modified="2019-10-16" version="1">MVDLIAERPFMLTFILLAFAVASAYGWMQTGKRAGLIIAGVFLLLIPIGIYVEKIWVTDRESLVDSILQIADALQANDHERVFQFIDPDAEPAIQSAKTELPRFHFDRAQVNMGGFRKFEIRSDLQPPEAIVDFTINVTVSMKDKSHTNAQVPRRLIVKFRKSGDIWRALEYTHLPVIGDPDGMSPNGGRPPTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQ33</accession>
    <name>A0A518IQ33_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">UDP-N-acetyl-D-glucosamine 6-dehydrogenase</fullName>
            <ecNumber evidence="5">1.1.1.136</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">wbpA</name>
        <name evidence="5" type="ORF">Mal33_11750</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.136" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016628">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047004">
        <property type="term" value="F:UDP-N-acetylglucosamine 6-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
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                <person name="Rast P."/>
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                <person name="Rohde M."/>
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    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQT4</accession>
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        <recommendedName>
            <fullName evidence="1">PlsC domain-containing protein</fullName>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PlsC" evidence="1">
        <location>
            <begin position="55"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="269" mass="30261" checksum="8C300E37392A3A86" modified="2019-10-16" version="1">MSETPTNPPVPEISRFLLRGFRRYSRRMIRKQFHAVAMLREGLAAARGIAPDQPLIVYGNHPGWWDPLAAHLVCETCFPDRDFFAPIDAAALQRYRILARLGFYPLEMGTATGAANFLRCSRAILDRPAASLWLTPEGRFCDPRDRSAELMPGLAHLCSRFERGAIVPLAIEYPFWEERLPEMLMALGDPIDVAAHREMSKSDWRALLTQRLRGTQDQLARVAIDRDTEALEIVLRGGRGSGAGYDLARRVRSLFSGTRYQASHGGKLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IR03</accession>
    <name>A0A518IR03_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Type IV pilin biogenesis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Mal33_15030</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003004">
        <property type="entry name" value="GspF/PilC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018076">
        <property type="entry name" value="T2SS_GspF_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30012">
        <property type="entry name" value="PTHR30012"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00482">
        <property type="entry name" value="T2SSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00812">
        <property type="entry name" value="BCTERIALGSPF"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="101"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="159"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="299"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="domain" description="T2SSF" evidence="7">
        <location>
            <begin position="204"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV55526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="332" mass="36380" checksum="9652DD0E7F81E55B" modified="2019-10-16" version="1">MSTFHDQIQATLEQRDLLIPPLTALAEEMPNSWGQRDLQELIDLLRNETDADAWMQHPRAAAWLPVIVGGFNPAETPQRIHLLFSQTMRQQQRQRQRGASLLYPFLILALAGAVGLGLSWGIVPTFAAMYRDFGLDLPLPTRISVAISDGIIQAPLKQLIIAAGAIALSVAIYRWWISSPLCSRLFSLKGNTRAVQAMAQAVGSVAELISVGASIPEALRISSRGCGHPLYQRELESLAGAAETSADTLNDSREATYFPANLLLALQPNATGHPNIHLLRELSLIYHERAAQRIDWLRWLVGPLALLAVGLVVVFVVFALFMPMISLVTSLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IR66</accession>
    <name>A0A518IR66_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Divalent metal cation transporter MntH</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">mntH</name>
        <name evidence="5" type="ORF">Mal33_15580</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046873">
        <property type="term" value="F:metal ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001046">
        <property type="entry name" value="NRAMP_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11706">
        <property type="entry name" value="PTHR11706"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01566">
        <property type="entry name" value="Nramp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="14"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="84"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="121"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="152"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="191"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="233"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="280"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="319"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="350"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="385"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV55581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="429" mass="44943" checksum="C0E5BD7E9B1C65C7" modified="2019-10-16" version="1">MNDQPSHQPWYRRIGPGLITACVVIGPGSLVTSSKVGASEQYSMLWVVVVSVAFMMLYMTLGAKLGAVGSAAPCDLIAAKAGRWLSVLVGLSVFFIATAFQSGNNIGVAATFEAFIDSKTVVAGMVILFNLLAIVFLFAFKDMYKMLERVMMALVGLMLISFAINLISLRPDLAAMGKGLVTPTLGKSGELLPILGLIGTTFISAAAFYQAYLVRQKGWGIDEVKSGMVDARIGSIIMFLITVMLMSTAAAGLSGRADITLNSPVDVAIALESTFGPAAKIIFCFGLFSAAYSSFLVNAMIGGFMAADGLNMGSRPTDLVPRLLTAASLLLGMAVGVAVLIFDFDRTPTIIAAQAVTVVAAPLIAGVLLWLTSSRDVMGEHVNRPATIVFGLIGLGLLLAMAGKTAFSDLPKKLESYLPAAASASSDPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IR78</accession>
    <name>A0A518IR78_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Planctomycete cytochrome C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Mal33_15720</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042806">
        <property type="term" value="F:fucose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010185">
        <property type="term" value="P:regulation of cellular defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001868">
        <property type="term" value="P:regulation of complement activation, lectin pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011429">
        <property type="entry name" value="Cyt_c_Planctomycete-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011444">
        <property type="entry name" value="DUF1549"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022655">
        <property type="entry name" value="DUF1553"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000421">
        <property type="entry name" value="FA58C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006585">
        <property type="entry name" value="FTP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00754">
        <property type="entry name" value="F5_F8_type_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07635">
        <property type="entry name" value="PSCyt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07583">
        <property type="entry name" value="PSCyt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07587">
        <property type="entry name" value="PSD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00607">
        <property type="entry name" value="FTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022068709" evidence="5">
        <location>
            <begin position="35"/>
            <end position="1151"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="6">
        <location>
            <begin position="30"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV55595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1151" mass="128434" checksum="00BD1009C98C6C9B" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IR91</accession>
    <name>A0A518IR91_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HlyD family secretion protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_15790</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990961">
        <property type="term" value="P:xenobiotic detoxification by transmembrane export across the plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030196">
        <property type="entry name" value="MdtN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30367:SF1">
        <property type="entry name" value="PTHR30367:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="393"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="684" mass="76265" checksum="A5A2DD56D28460B2" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRB5</accession>
    <name>A0A518IRB5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">50S ribosomal protein L35</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 7" type="primary">rpmI</name>
        <name evidence="7" type="ORF">Mal33_16230</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the bacterial ribosomal protein bL35 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.410.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00514">
        <property type="entry name" value="Ribosomal_L35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021137">
        <property type="entry name" value="Ribosomal_L35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001706">
        <property type="entry name" value="Ribosomal_L35_non-mt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037229">
        <property type="entry name" value="Ribosomal_L35_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33343">
        <property type="entry name" value="PTHR33343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01632">
        <property type="entry name" value="Ribosomal_L35p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00064">
        <property type="entry name" value="RIBOSOMALL35"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143034">
        <property type="entry name" value="SSF143034"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00001">
        <property type="entry name" value="rpmI_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="18"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV55645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="67" mass="7531" checksum="E0389673EBD3888C" modified="2019-10-16" version="1">MPKMKTHKGTKKRFRLSATGKAMHRKSGTSHLQARMSQKRKRNLRGTGAMDVCMEKTIHAALSGNSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRC1</accession>
    <name>A0A518IRC1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Inositol-1-monophosphatase</fullName>
            <ecNumber evidence="4">3.1.3.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">suhB_1</name>
        <name evidence="5" type="ORF">Mal33_16160</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>a myo-inositol phosphate + H2O = myo-inositol + phosphate</text>
            <dbReference type="Rhea" id="RHEA:24056"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17268"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:84139"/>
            <dbReference type="EC" id="3.1.3.25"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the inositol monophosphatase superfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.25" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008934">
        <property type="term" value="F:inositol monophosphate 1-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052832">
        <property type="term" value="F:inositol monophosphate 3-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052833">
        <property type="term" value="F:inositol monophosphate 4-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046855">
        <property type="term" value="P:inositol phosphate dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01639">
        <property type="entry name" value="IMPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033942">
        <property type="entry name" value="IMPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020583">
        <property type="entry name" value="Inositol_monoP_metal-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000760">
        <property type="entry name" value="Inositol_monophosphatase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00459">
        <property type="entry name" value="Inositol_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00377">
        <property type="entry name" value="IMPHPHTASES"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00629">
        <property type="entry name" value="IMP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU364068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV55638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="263" mass="28606" checksum="2E70E37E426769B3" modified="2019-10-16" version="1">MNDNYLKVARLAAAAGAEILLSYQGRFSVREKAPRDLVTEADVAAQQAIQKILLSNFPDHGFVGEEEGHDQVSAEMLADPNHPPIWIVDPLDGTVNYVHQLQSFAVSIAMYHRGELQLGVVHDPVTKEIFWAQRGGGAFLNDCPIQCSQSDRLDQALLACSFSAGVRHDSGELDRFAAALDQAQAVRRLGSAALNLCYVAAGRLDGYWATCVKPWDVAAGAVIVSEAQGEILSLAGEKFDIWDPRFVATATKSLNDQLRRCLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRF8</accession>
    <name>A0A518IRF8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_16380</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="443" mass="49657" checksum="185FF2C98E606CEC" modified="2019-10-16" version="1">MNSKLSLTHSTALTNEPNHWCCALSDRYRFTLSADLVDWFAREIWLRDQGGEFDQPVSPSELLCETPDFIWPGFMLPDSLPLVGNRYGDWLCLRVGADNSVAEVIHWYHGGGDWMPWGATLAEAVAFDSLRSRLPGRRQYYANIAADFAQQSGPATIPGWAADHLPAAIGKLLLDELGDTDEIPGLGELMIQHDVASTAVHGESALAALDSLLRQKLEPWAARELGIQWDQDAIRWLFDNDLIQPSVLQRLADHFGCDSKDLRGQDWDVAIAHATAVVAKRDDLGWASDILGWAAERAGRPDAAIAAYRNALRCSSFADQSVRFRTHWFRESEGKFAAARLQELGADLQHDSYLRLFRESKDQGLRSRVTNYWMRIAEQAASDERWAEAYDAYYRAGWDMGCDDLEVYEELLSRLADAAERSGMVSRAALAKTHLACLANRLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRV7</accession>
    <name>A0A518IRV7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_17930</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="292" mass="32042" checksum="9E77B835AFE67CD6" modified="2019-10-16" version="1">MTNSDPSGFAPRWYRNADQQTRAALAETSLLGVPAPQSPQIITRLLPNAGGQTLAASAVAKVIELTQRLAHYAAQDLVVGINPNFADMRSISAEVQAFSRLAIEPFEEGSFVIPAQLESQDFETESGDQIATEQIAQRFSDILLTISSGQRATEISIGALQTVRQLNATINTAASVVEYQTIDRFQQATAAMRVDAEFMGRVRKIIDGRQPSAERLDSLTGTVTALDILRGQIQLTVDDRKQRIKGSFHKMLQPTMLESLGRVVKLYGAISYKHDQPVEISIQEAELIDEDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRZ7</accession>
    <name>A0A518IRZ7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transposase DDE domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_18330</name>
        <name evidence="4" type="ORF">Mal33_23600</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002559">
        <property type="entry name" value="Transposase_11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01609">
        <property type="entry name" value="DDE_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_1" evidence="2">
        <location>
            <begin position="165"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="423"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="440"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV56371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="460" mass="51290" checksum="09186FCF64BFB0C7" modified="2019-10-16" version="1">MTVDELLDRFKNECPVAMGTRLMLNHLLSDERMDTLFATHAGSQRCGELLFSSVADIMACVALNIKPSVNAAYKKHKEKLKVSVTSVYNKLQGIETQVSRVLVSETAAELSQLWDHLEGPKPPPVLSGYKTRIIDGNHLAGTEHRIKELRTLGAAALPGTTIPILDPDKKLLVDVILSRDGHANEATLHPEILELVEKGEVWIGDRHFASQKMMTTIALDKKAFFVFRHSKGLLPNWESQGERRRIGRCDGGTIYEQKIAFTYQGRAICPRRVTIELDTPTRKGDTAVHVLTNLPSRVSAKSVANAYRKRWNIETAFQHLATTLNSEINTLGYPQAALFSFCMSMMMYNLISVMKTSIGCAAGDADLADEVSSYYAANDVSESWKGFMTAVTEKEFDSVYGKLTLKQLAKELVDVARKLDFSQYRKSHRGPKKPPPKRKSGNRGNHESTARILDQRAPKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IS79</accession>
    <name>A0A518IS79_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BatA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_19130</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024163">
        <property type="entry name" value="Aerotolerance_reg_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011933">
        <property type="entry name" value="Double_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07584">
        <property type="entry name" value="BatA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02226">
        <property type="entry name" value="two_anch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="BatA" evidence="2">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="770" mass="83039" checksum="B9FA81ED7038A41D" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISB2</accession>
    <name>A0A518ISB2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_19660</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024486">
        <property type="entry name" value="DUF2617"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10936">
        <property type="entry name" value="DUF2617"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="179" mass="20312" checksum="50FC9801F96BDB8B" modified="2019-10-16" version="1">MLSVRPKIAELTFQVFGRSLHPELFEFHRSRRIQRDAFHAEISITNSGHVVTWRGNGITISEVAASSQQLLPTRRRLMEYPLRGSRTDRAECRSGVTYSTRFTLEPVATDLFWTIQKQLTADATEGLLHRFDSNGRIAMGAVSYINIETRARSMMIQAIHTFPEDQAIVKVESTFAIDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISC4</accession>
    <name>A0A518ISC4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Inorganic diphosphatase</fullName>
            <ecNumber evidence="3">3.6.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Pyrophosphate phospho-hydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Mal33_19770</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>diphosphate + H2O = H(+) + 2 phosphate</text>
            <dbReference type="Rhea" id="RHEA:24576"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="EC" id="3.6.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="3.6.1.1" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004427">
        <property type="term" value="F:inorganic diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.310.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1390.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001667">
        <property type="entry name" value="DDH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038763">
        <property type="entry name" value="DHH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004097">
        <property type="entry name" value="DHHA2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038222">
        <property type="entry name" value="DHHA2_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010766">
        <property type="entry name" value="DRTGG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028979">
        <property type="entry name" value="Ser_kin/Pase_Hpr-like_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01368">
        <property type="entry name" value="DHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02833">
        <property type="entry name" value="DHHA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07085">
        <property type="entry name" value="DRTGG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01131">
        <property type="entry name" value="DHHA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64182">
        <property type="entry name" value="SSF64182"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75138">
        <property type="entry name" value="SSF75138"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0129">CBS domain</keyword>
    <keyword evidence="5 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0464">Manganese</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="9">
        <location>
            <begin position="72"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="9">
        <location>
            <begin position="255"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00032535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV55998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="553" mass="60678" checksum="4503A6C01E3738D7" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISE1</accession>
    <name>A0A518ISE1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Zinc transporter ZupT</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_19810</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="158"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="183"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="215"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="238" mass="24729" checksum="9F38B910F14EDD08" modified="2019-10-16" version="1">MSELVQVLLLTTMAGAAIPIGGAIAMVERISPQWLEEELRHSVIAFGGGVLISAVALVLVPDGVKALSLGWIVAAFVAGAIAFWGLETLLARSQSSIAQLVAMLSDFIPEAIALGAAFAHGESTGALLAVLIALQNLPEGFNAFRELRVSGNVRGGKLVLMLAACVPLGPLAGWIGYHHLAEYPSVVGFIMLFAASGILYLTFQDLAPQSRSESQRAPAIGAVFGFLLGVIGQVLLDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISH0</accession>
    <name>A0A518ISH0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Arylsulfatase</fullName>
            <ecNumber evidence="3">3.1.6.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">atsA_17</name>
        <name evidence="3" type="ORF">Mal33_20250</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="PTM">
        <text evidence="1">The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.</text>
    </comment>
    <dbReference type="EC" id="3.1.6.1" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004065">
        <property type="term" value="F:arylsulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sulfatase" evidence="2">
        <location>
            <begin position="69"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="modified residue" description="3-oxoalanine (Cys)" evidence="1">
        <location>
            <position position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR600917-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="531" mass="59313" checksum="3E631C9EFF3BF595" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISH4</accession>
    <name>A0A518ISH4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">6-phosphogluconolactonase</fullName>
            <shortName evidence="7">6PGL</shortName>
            <ecNumber evidence="5 7">3.1.1.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">pgl_1</name>
        <name evidence="7" type="synonym">pgl</name>
        <name evidence="9" type="ORF">Mal33_20210</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 7">Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12556"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57955"/>
            <dbReference type="ChEBI" id="CHEBI:58759"/>
            <dbReference type="EC" id="3.1.1.31"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 7">Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 7">Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.31" evidence="5 7"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00409"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017057">
        <property type="term" value="F:6-phosphogluconolactonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01400">
        <property type="entry name" value="6PGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005900">
        <property type="entry name" value="6-phosphogluconolactonase_DevB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006148">
        <property type="entry name" value="Glc/Gal-6P_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039104">
        <property type="entry name" value="PGLS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11054">
        <property type="entry name" value="PTHR11054"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01182">
        <property type="entry name" value="Glucosamine_iso"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01198">
        <property type="entry name" value="pgl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucosamine_iso" evidence="8">
        <location>
            <begin position="16"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00020337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV56042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="245" mass="27090" checksum="6EF90D5975ED4236" modified="2019-10-16" version="1">MTKPTLGSLEVFDDIASISRQACDDLIPLCCDAIAARGVCRIALAGGSTPKLLYRLMAENQQAFDWAKIELFWGDERNVLPEDDDSNFRMVREAMLDHVPIPEANVFRVPIDPADPAATALQYEATLKAQFGGDSLDWDLVLLGMGDDAHTASLFPQTKAIDANDRLFVENWVEKFDTFRQTLTAPAINSARNVWFLIGGAGKREALQHVWGARQAPSEFPSQLIRPSAGKLRWMIAIDAMPETA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISU1</accession>
    <name>A0A518ISU1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_21430</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="110" mass="11802" checksum="AA9CA89DFE26C9B0" modified="2019-10-16" version="1">MTAGASAAAVVTGSSRFANACRFKELLDWFSSRLIVAPASQVVGLLSQLETGDREFSVDDLAMVVPRKSRLGILRRSSDECLQRGDNLIGLGSLPIIHVDETPSHDSFAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IT98</accession>
    <name>A0A518IT98_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Serine hydroxymethyltransferase</fullName>
            <shortName evidence="7">SHMT</shortName>
            <shortName evidence="7">Serine methylase</shortName>
            <ecNumber evidence="7">2.1.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 10" type="primary">glyA</name>
        <name evidence="10" type="ORF">Mal33_22980</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + glycine + H2O = (6S)-5,6,7,8-tetrahydrofolate + L-serine</text>
            <dbReference type="Rhea" id="RHEA:15481"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="EC" id="2.1.2.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7 8">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Amino-acid biosynthesis; glycine biosynthesis; glycine from L-serine: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the SHMT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.1" evidence="7"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00193"/>
    <dbReference type="UniPathway" id="UPA00288">
        <property type="reaction ID" value="UER01023"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004372">
        <property type="term" value="F:glycine hydroxymethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019264">
        <property type="term" value="P:glycine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00378">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00051">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001085">
        <property type="entry name" value="Ser_HO-MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019798">
        <property type="entry name" value="Ser_HO-MeTrfase_PLP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039429">
        <property type="entry name" value="SHMT-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11680">
        <property type="entry name" value="PTHR11680"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00464">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000412">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00096">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4 7" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="6 7 8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SHMT" evidence="9">
        <location>
            <begin position="4"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="121"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="31"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="95"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="117"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="200"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="225"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="357"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="7 8">
        <location>
            <position position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000412-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV56316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="420" mass="45161" checksum="63A9EBA637718312" modified="2019-10-16" version="1">MNILEQQDPEIWQAIANEAERQRDGLEMIASENYTSRAVMQAAGSVLTNKYAEGYPGRRYYGGCEYADVVERAAIKRATDLFGAEAANVQPHSGSQANTAVYMTVLEPGDKVLGLDLAQGGHLTHGMKLNISGKLYDFHSYGVDREHHRLDFDQIAKMARELKPKMIVAGASAYPREIPHDKFAEIANEVGAKLMVDMAHYAGLVAAKIHNNPVPVADYVTTTTHKTLRGPRSGLILCKQDDLKDINRSVFPGIQGGPLMHIVAAKAVCFSEAASSDFRAYGQQVVDNAKVLAETLIAGGLTLVSGGTDNHLCLVDVTAFGIGGKLAEAALEKCGITVNMNMIPFDTRKPMDPSGIRIGTPALTTRGMKVEQMRTIGNWIIQALKSHDDDAALASIRGQVSELCQGFPVPADATAPSATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITM7</accession>
    <name>A0A518ITM7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ribosomal RNA small subunit methyltransferase C</fullName>
            <ecNumber evidence="2">2.1.1.172</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rsmC</name>
        <name evidence="2" type="ORF">Mal33_24310</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.1.1.172" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052914">
        <property type="term" value="F:16S rRNA (guanine(1207)-N(2))-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007848">
        <property type="entry name" value="Small_mtfrase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05175">
        <property type="entry name" value="MTS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MTS" evidence="1">
        <location>
            <begin position="194"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="360" mass="39106" checksum="E5B5E3D9C22D6E1F" modified="2019-10-16" version="1">MPDSPLPESSPHALPARPAEQFLIQQFSEGNLLPAAGDVLTTSLGRAQLAAALAASNQYDRVDCWYIDLYQANHARAHHPEPPASLNIVCEPDPPEHQYDLAVLPLGRRGETELVRDQLQSFFNALKIGGQLWVAVDNPTDKWVHEQIVKLGVKPTTISGSDSIVYGCVKTAELKKQKNYGCEFAIRDRGRLLNVYSRPSVFSHRRIDPGARHLIDAMPIEAGMRVLDLGCGAGTVSLAAATAADDVTVHCIDSNSRAVQCTLAGAELNQLTNVTASVSDTGQIDAPGSFDLVLGNPPYYADFRIAELFMATAHKALRSGGRVVLVGKDEEWYTDQMPVLFHSIEIQPVKGYLVASGTRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITR0</accession>
    <name>A0A518ITR0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">DNA-invertase hin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">hin</name>
        <name evidence="8" type="ORF">Mal33_24580</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the site-specific recombinase resolvase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000150">
        <property type="term" value="F:DNA strand exchange activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006118">
        <property type="entry name" value="Recombinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006119">
        <property type="entry name" value="Resolv_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036162">
        <property type="entry name" value="Resolvase-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006120">
        <property type="entry name" value="Resolvase_HTH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02796">
        <property type="entry name" value="HTH_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00239">
        <property type="entry name" value="Resolvase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00857">
        <property type="entry name" value="Resolvase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53041">
        <property type="entry name" value="SSF53041"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00397">
        <property type="entry name" value="RECOMBINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51736">
        <property type="entry name" value="RECOMBINASES_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0229">DNA integration</keyword>
    <keyword evidence="4" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Resolvase/invertase-type recombinase catalytic" evidence="7">
        <location>
            <begin position="4"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="active site" description="O-(5'-phospho-DNA)-serine intermediate" evidence="5 6">
        <location>
            <position position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR606118-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV56468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="199" mass="21999" checksum="92EFD6CCE63B7464" modified="2019-10-16" version="1">MTQHIAIYARVSSKKQDTRSQQADLDQWIAAFAKDQPIKWYKDKFTGKTMDRPGWKRLESDMTAGKVSKVVVWRMDRLGRTASGLTALFEEFQRLGIGFESLKDKVDLSTAAGRLLANVLASVSAYENEVRSERVLAGQQAARAAGKTWGGSQKGRRLTVTDEQIATVRRMQADGESKAAMARATGLSRPTVYSILAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITX0</accession>
    <name>A0A518ITX0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_25280</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014942">
        <property type="entry name" value="AbiEii"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08843">
        <property type="entry name" value="AbiEii"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="309" mass="34323" checksum="AA0CB6FCE024A355" modified="2019-10-16" version="1">MTRDLAASVRGRLLRQAKESGRPLQELLQYFAMERFLFRLSRSEHADRFVLKGALMFRVWGTPQTRATRDIDLLARADNSVDSMTQIMRSVCEHAVAPDGVIFHGESVQGIAIKEDADYLGVRVTFLATIQNARLPMQIDIGFGDVVNPAAITIAYPTMLDFEPAKLIGYPRETVIAEKFEAMVKLGQLNSRMKDFYDILILSRQFDFDGDSLATAISATFRNRGTTAKASPPAFSNEFVNDPGKQIQWASFIRKSKLSDVPDALADAIREIAGFLNPIAKTIESNEPFAATWSPGSGWIQSQPPTNSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IU54</accession>
    <name>A0A518IU54_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_25920</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="304" mass="33626" checksum="8A634F5B45730654" modified="2019-10-16" version="1">MTPTTLSAARPNARLRKAEANARPLVTIFTVLKPFVGEADTHQRNALASWQMLGPDVEILLFSDTSIPDDLRARFTCLPCIATNEFGTPLLDDVFRVAADIARGSVRAFVNGDIVLDQRFTQSVRRLQDSDLASWLAIGQRTELDVPAAVQHPAAGWLDDCFQKCETQGELASVVCKDYFIFTADLFQDLPAFAIGRGNWDNWMVAHSKSNGIPVVDITAVAPVIHQRHGYAHVSGGRGAVYVSGPEAKENQRLAGGRHLISGSTANWRFDKSGIRRVRWTSWTLCKDAFRFAGLLLRMLMRSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IU66</accession>
    <name>A0A518IU66_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">Translation initiation factor IF-3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 8" type="primary">infC</name>
        <name evidence="8" type="ORF">Mal33_26290</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 5">IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 5">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4 5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the IF-3 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00080">
        <property type="entry name" value="IF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036788">
        <property type="entry name" value="T_IF-3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036787">
        <property type="entry name" value="T_IF-3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019813">
        <property type="entry name" value="Translation_initiation_fac3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001288">
        <property type="entry name" value="Translation_initiation_fac_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019815">
        <property type="entry name" value="Translation_initiation_fac_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019814">
        <property type="entry name" value="Translation_initiation_fac_3_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10938">
        <property type="entry name" value="PTHR10938"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00707">
        <property type="entry name" value="IF3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05198">
        <property type="entry name" value="IF3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54364">
        <property type="entry name" value="SSF54364"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55200">
        <property type="entry name" value="SSF55200"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00168">
        <property type="entry name" value="infC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00938">
        <property type="entry name" value="IF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4 5" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3 4 5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="IF3_N" evidence="7">
        <location>
            <begin position="19"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="IF3_C" evidence="6">
        <location>
            <begin position="94"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV56636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="178" mass="20206" checksum="354FD8BFDD82B0B0" modified="2019-10-16" version="1">MALARRGMQPQVERDSTRINTQIRISPIRVVGPEGDQLGVISTEDALSRARDAGLDLVEVAPNERPPVCRIMDYGKYKYDKNKKKNSHTSHQTKTKEIRLRPKTGQNDIDTKIRQAEKFLGHKDKVQVSVLFRGRENAHIDEGEKVMELVLEQLAEVGKVESAPQRNGRRIICMLAPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUB1</accession>
    <name>A0A518IUB1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Multifunctional CCA protein</fullName>
            <ecNumber evidence="2">2.7.7.72</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">cca</name>
        <name evidence="2" type="ORF">Mal33_26700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.7.72" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052929">
        <property type="term" value="F:ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052928">
        <property type="term" value="F:CTP:3'-cytidine-tRNA cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052927">
        <property type="term" value="F:CTP:tRNA cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016437">
        <property type="term" value="F:tRNA cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HD" evidence="1">
        <location>
            <begin position="246"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="370" mass="42888" checksum="20B025F8F3DDC2DE" modified="2019-10-16" version="1">MASPKLRYAIAWEAARLLYDHEESEYYRAKLKAARRVQKSWVKPADLPSNAEIRDQVQMMARMHEGDLGHSQRLHKMRLRALWWMRQLQAFHPYLIGSVLTGHVRDGSDIDIHVFASNPQSILMHVEETGSGCQMERKRVRKDGEERVFTHIHLRDEFPVELTVYHPSLIGHRFKSSITGKAIERASLPQLQRLIELEHGQGIDQQDHALEEAECQVDRFQLYESLLWPLENVKQNLKYHPEGDALYHSLQVFEHARDEMPYDEDFLLAALLHDVGKAIDPQDHVAAGLEELDGFIQPRTAWLIEHHMLAHQLRDRTLGARARRRLVEHPWHDDLVALSDADRLGRQQGVQVDDVGDALDYIRSLETMFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUB9</accession>
    <name>A0A518IUB9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_26890</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="171" mass="17524" checksum="DD94B74851FACD2F" modified="2019-10-16" version="1">MFKFAKVSFMAGVVAIAGCGDAGPPRVPITGTLTLDGEPLAFKSLTLTPIEGTTGGGASGYSDSEGKYQVLAMVPGAVQDFNGCPPGRYRVTVSEPLIPISDADFQTASKGEVIDSNEPAAAVFMPTTPRKKKQAKGAIPSVYASGTMSPLVIDVAEGNELIDLALASTAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUE8</accession>
    <name>A0A518IUE8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">pknB_11</name>
        <name evidence="9" type="ORF">Mal33_27060</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="418"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="449"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="472"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="500"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="525"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="93"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV56708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="562" mass="61365" checksum="BCCB53ACA932F05F" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUE9</accession>
    <name>A0A518IUE9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Quinohemoprotein alcohol dehydrogenase ADH-IIG</fullName>
            <ecNumber evidence="3">1.1.9.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">qgdA</name>
        <name evidence="3" type="ORF">Mal33_27220</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.9.1" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025666">
        <property type="entry name" value="PQQ-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018391">
        <property type="entry name" value="PQQ_beta_propeller_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002372">
        <property type="entry name" value="PQQ_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01011">
        <property type="entry name" value="PQQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13360">
        <property type="entry name" value="PQQ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13570">
        <property type="entry name" value="PQQ_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00564">
        <property type="entry name" value="PQQ"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022122417" evidence="1">
        <location>
            <begin position="19"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="domain" description="PQQ_3" evidence="2">
        <location>
            <begin position="50"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13570"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="412" mass="44912" checksum="7382ED0956447BC1" modified="2019-10-16" version="1" precursor="true">MKSIAALIVLLLAGTAVAEQPNWNQFRGPDGDGKTGATGLPVTWSDTENVVWKTPVHGKGWSSPVVWDDQIWMTTASEDGKQMSAVCVDFNSGKVVHDVPLFENAEPRYCHPQNSYASPTPVVEAGRLYVHFGSYGTACVDTTKGAKIWERRDLICNHWRAPGASPIVHGNLLIVAYDGYDNQFVIAFDKQTGETAWQVDRNIEYGTDNGDHKKAYSTAKIIQHDGRSEMISPGAVATIAYDPETGKELWKVYHGGMNAAPRPLFANGLVYITGGANDLGLIAVRPGGTGDVTDSHIVWGKGRGMPKRGSQIIVDDLMFAITDDGIAICLDAKTGDQIWKHRLGGDFWASPLYADGRIYGFNKDGDCPVFEASDKFKLLADNKLPETICASPAVVGNSLIIRTQSHLYRIEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUJ9</accession>
    <name>A0A518IUJ9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Inner membrane protein YiaW</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">yiaW_1</name>
        <name evidence="3" type="ORF">Mal33_27640</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011223">
        <property type="entry name" value="UCP028770"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11742">
        <property type="entry name" value="DUF3302"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028770">
        <property type="entry name" value="UCP028770"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="28"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="98" mass="10247" checksum="AAD01578430CE05E" modified="2019-10-16" version="1">MIVVVTLGQLPGQIASQRNHPQAAAVNIAGWLGVATLGILWPFAMIWAYLKPFSAAANGANSDRESQSSASGDGQAQLAKMQTQVDSLQAALNKLNAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUN1</accession>
    <name>A0A518IUN1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_27990</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="161" mass="17291" checksum="E4914C349AC875C4" modified="2019-10-16" version="1">MNSIKRFDFFPFPVLLGFLLMLGCDGNNQVPTYVTTGVVHFEGKPMKGGGAISFVPVGKQTGMPAGGSIAEDGTFVMSTYGEGDGSVPGKFRVTIMQTTAAEPTMTQNEDGSEPTMATEPTVTVRPEDTIPLTYADPLNTPLEVEVKAQENNELVIELKRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUU8</accession>
    <name>A0A518IUU8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ribose transport system permease protein RbsC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rbsC_2</name>
        <name evidence="7" type="ORF">Mal33_28600</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="35"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="83"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="113"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="162"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="210"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="295"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV56859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="332" mass="35382" checksum="B1F3AA95B18DD06A" modified="2019-10-16" version="1">MKKILGILGLLVFICVVTALMSDRFLTQFNIENLIRRSALFGIISVGAAFVIITGGIDLSIGSVVCMIGCLLPWMLVQQEFSVPLALLISLGISLAVGLSHGLLITKVRLQPFVVTLCGLLVYRGITRGIVQDQTQGFKSGYQSLRALAQGQMPLPGTDFGIPYPCLILAVVAALAILFLNYTIYGRYMLALGRNETAARYSGINTDRMIILAYMICALLSGLGGMLFVLDVGSAQPVDFGNFYELYAIAAAVLGGCSLRGGEGTIIGVVIGAAVMQVLKNSITLIDAIPTNIEFAVIGIVILGGVIADEYVKRFAAARRARLQAELAQQAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IV07</accession>
    <name>A0A518IV07_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">BON domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_29250</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007055">
        <property type="entry name" value="BON_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04972">
        <property type="entry name" value="BON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50914">
        <property type="entry name" value="BON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022081391" evidence="1">
        <location>
            <begin position="23"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="domain" description="BON" evidence="2">
        <location>
            <begin position="31"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="204" mass="22624" checksum="4736DC195164E8B1" modified="2019-10-16" version="1" precursor="true">MKAINTIAALLFAAFTASQLQADSEYPIRPPDQVIQRDVDEELRSLIHRIPAAVEARVVAGEVTLQGGVSSFLDRMRIGRRVAGVEGVSRVNNRLRVERMPVRTQQRDDRTVDRRDDFADLSKKQPAGKHTLRGMIDSKREGMLVVRDFRAGRSEVAMLDATEVTLNGARVDGDQIDEGLLVFIRGRRDGGRLVAASVEAYSPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IV22</accession>
    <name>A0A518IV22_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sugar phosphate isomerase YwlF</fullName>
            <ecNumber evidence="3">5.3.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ywlF_2</name>
        <name evidence="3" type="ORF">Mal33_29400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LacAB/RpiB family.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.-" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016861">
        <property type="term" value="F:intramolecular oxidoreductase activity, interconverting aldoses and ketoses"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1400.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004785">
        <property type="entry name" value="RpiB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003500">
        <property type="entry name" value="RpiB_LacA_LacB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036569">
        <property type="entry name" value="RpiB_LacA_LacB_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02502">
        <property type="entry name" value="LacAB_rpiB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005384">
        <property type="entry name" value="RpiB_LacA_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89623">
        <property type="entry name" value="SSF89623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01120">
        <property type="entry name" value="rpiB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00689">
        <property type="entry name" value="rpiB_lacA_lacB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="65"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR005384-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="149" mass="16185" checksum="C764CFE76C5E4AC1" modified="2019-10-16" version="1">MKVSIASDHRGVHIKARIAQALESNGHTVFDEGADCEDASDYPDFASIVAQKVSQGECDRGILICGTGIGMAITANKFAGVRAAPCYDEVMVELSRRHNDLNVLCLGGDLIGDRNIDDLILLWMRTEFEGGRHARRVDKIVSIEEGNAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IV32</accession>
    <name>A0A518IV32_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Methyl-accepting chemotaxis protein PctB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">pctB_2</name>
        <name evidence="7" type="ORF">Mal33_29480</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyl-accepting chemotaxis (MCP) protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004089">
        <property type="entry name" value="MCPsignal_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00015">
        <property type="entry name" value="MCPsignal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00283">
        <property type="entry name" value="MA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50111">
        <property type="entry name" value="CHEMOTAXIS_TRANSDUC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0807">Transducer</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="396"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="6">
        <location>
            <begin position="420"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="domain" description="Methyl-accepting transducer" evidence="4">
        <location>
            <begin position="479"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="5">
        <location>
            <begin position="652"/>
            <end position="714"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00029447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV56947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="779" mass="84313" checksum="71598466925C6BD1" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVD9</accession>
    <name>A0A518IVD9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_30620</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011453">
        <property type="entry name" value="DUF1559"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07596">
        <property type="entry name" value="SBP_bac_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="365" mass="39250" checksum="B776BBB2CD5FC83F" modified="2019-10-16" version="1">MARVRLWPTTPKSLMSHSIKHEFSYAVAPTSLAKNSKRGFTLVELLVVISIIGVLVGLLLPAVQAAREAARRMSCSNNLKQIGLSLHNYESAFRVFPSQSSSPGPGAEWTTQRGSWFTSILPFIEQDGLFSSFDSDYHWHAPENLEAVSTEVPMLRCPSAPDRPGFEWTVLIDYPNGSSTYSLTARDTYYGATTDYANVGGVGSQLSATLPPQQQLSDPSNCGVLKSTAVRLAEIIDGLSNTVLLVECAGRPVLYQKGRAVPDGATPKTWSGSSSVTRPLPTGGVWASHNKGFLVYGSQPDGNTAIRPGLCSVNCSNDNEVYAFHPGGANVLMSDGAVRFISESLPIEQLVALVSRNGREVVSID</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVT5</accession>
    <name>A0A518IVT5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_32090</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="126"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="264"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="404" mass="45404" checksum="BD4FAB83B3404921" modified="2019-10-16" version="1">MQKSLSESLDQFEEVLDRFEEKNLNASDDVDADEQSEAVETITKDHELDVAATQLCEVLQRKSLPNKPPHRPGTAYRKLIAASGGMSESTMLRNGFSPSIIGDTEVMHDSVDLLCRWIVETRQNTSSSATAETRLAREKHNNGDMPNQGSSMFNPADCDDDLWGQLNTCVKAMETTFAKAPSLIVQRKIGTQDSKYLQNINQLATEAGWVPFVFRREGVLEVLRTNGKKAVCHYAPHNHSLDEVGGEAILNALRAWREKRVQELRLSSGPAPENTTDPIGGQGVTPPHPSNKKSKNKRVASKPLESMEIRELRQLAIIADLHFQWLQNGRKPKKTSTSFDDWLHEHGYHEGKRRYGEAYRHHNTHKSRQGHGASDTTKTTLKEALKLQERWVEVVRSAIDQLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVX9</accession>
    <name>A0A518IVX9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Rhomboid protease GlpG</fullName>
            <ecNumber evidence="8">3.4.21.105</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">glpG_1</name>
        <name evidence="8" type="ORF">Mal33_32410</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="3.4.21.105" evidence="8"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022764">
        <property type="entry name" value="Peptidase_S54_rhomboid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01694">
        <property type="entry name" value="Rhomboid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="SSF144091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="66"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="107"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="132"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="160"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="Rhomboid" evidence="7">
        <location>
            <begin position="64"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="226"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="263"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV57237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="282" mass="32010" checksum="685A68456E9D029E" modified="2019-10-16" version="1">MGLYDRPYYQDEERSHLPPSLASQSFVIVLIVINVAVFFADFIFGGEGFALRTAMEVTPQTIVKPWLWWQFVTYGFAHGNMNHILFNMIGLFFFGRIVEQRLGKIEFLRFYLVAIILGGIAWSLRANLTGSLAPGVIGASGGVIAVTMLFIFWYPQTEIYLMMVLPVKAWIVGVLMIAGNLFGMGSATTAFDVHLVGIAFASAYYYFHWNLASISPAGLSKLTRPSTRLKLHDPDRQSRQERRDAEEAERILQKIHEHGEGSLTNAERKVLERHSRHLRDRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVZ2</accession>
    <name>A0A518IVZ2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_32620</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021822092" evidence="1">
        <location>
            <begin position="30"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="135" mass="14289" checksum="4570324A45B72562" modified="2019-10-16" version="1" precursor="true">MKTKLFALLPVALLTLASIGCGSSGPAMSQVSGKVTFDGEPVTTGHVIFRANDGKTISAAGPIVDGSFDFESMPGEKTVLITATRPVPGKFDESNPGEKIQITEQFIPENYNSKSELSVVVTEEDGTFDFDLQSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IW32</accession>
    <name>A0A518IW32_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">L-glyceraldehyde 3-phosphate reductase</fullName>
            <ecNumber evidence="2">1.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">gpr</name>
        <name evidence="2" type="ORF">Mal33_32970</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.1.-" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="1">
        <location>
            <begin position="15"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="345" mass="38579" checksum="2382F340876FF857" modified="2019-10-16" version="1">MQRRPIGRSGLVVSEICMGTMTFGSQCDEPTSFAIMDRAFEAGIDFFDAAELYPVPPKAETVGVTEEIVGRWMKTKPRDQVLIASKITGPGHGWFRPPVRGGVTAIDRHQIIRCCDQSLQRLGTDYIDLYQTHWPDHNMRYEETLGALTELKQAGKIRAIGCSNETSWGVMKSLWQAEKHGTMRYDTVQNNFSLINRRCESELAQVCRQESVGLLPYSPLGGGVLTGKYNDQNPIGGRFTEYLENGEPRQQRMARRFVNERTIETTRRLKVIADEIGVSLATLAVAWSKQHDFVASTIIGATSVDQLNESLPAADLVLDAQTMERIDAIDAEIPNPMTEDGLRRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IW99</accession>
    <name>A0A518IW99_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_33620</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011453">
        <property type="entry name" value="DUF1559"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07596">
        <property type="entry name" value="SBP_bac_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="366" mass="39008" checksum="E18BCF34016EADD3" modified="2019-10-16" version="1">MKRRGFTIIEMLVTLTIIGVLASLLLPATNMAREAARQTQCANNLRQMGTALLARAEQDKGRLCSGSFDWANDGAVTDIGWVADLVRDGIAPSEFRCASNPSQISAAYRDLIEMSVADAGNEACTPRLGKAPVTQIDGTIAKNYALTIVDENLAASGADRIAVLTRDVYDRGFNTNYAASWFLVRGGVRLDDSGNLDPADAGCSTDIDHPNVTTGPLTTKQIASARAPSYTIPLLCDAKSNEALTTDFGDRLGGEPMTRTMVGGAITISGMATPSFAAGTARAGASGWWKVWNKETLQDYRGMFPLHRGICNVVMADGSVKQLFDENEDGFINNGFPQNSDFQSGVIEAAPLQLASTYTLTTGDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWT2</accession>
    <name>A0A518IWT2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_35350</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
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                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">Mal33</strain>
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    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="project" value="UniProtKB-KW"/>
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            <end position="48"/>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="49" mass="5436" checksum="96EBB8CFDAD0D381" modified="2019-10-16" version="1">MLMRNPEMTLVDSLDRDEEILASSARENLLGQVIVILVVVVAILLRSLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
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    <name>A0A518IWW0_9BACT</name>
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            <fullName evidence="2">PSCyt1 domain-containing protein</fullName>
        </recommendedName>
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        <name evidence="3" type="ORF">Mal33_35820</name>
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        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
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            <taxon>Planctomycetia</taxon>
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            <taxon>Rosistilla</taxon>
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    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
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                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
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            <strain evidence="3 4">Mal33</strain>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022086086" description="PSCyt1 domain-containing protein" evidence="1">
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            <begin position="24"/>
            <end position="588"/>
        </location>
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        <location>
            <begin position="40"/>
            <end position="95"/>
        </location>
    </feature>
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    <evidence type="ECO:0000259" key="2">
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            <dbReference type="Pfam" id="PF07635"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="QDV57571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="588" mass="65831" checksum="DE3A4FABA1D0CCDC" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
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    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
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                <person name="Amann R."/>
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                <person name="Mascher T."/>
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                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">Mal33</strain>
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    </reference>
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        <location>
            <begin position="35"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="206" mass="21798" checksum="7101C67B42CECB5F" modified="2019-10-16" version="1">MNLRMLLCAVSCSLLILSGCDSKIAGKSDGTDSAATSQDQASQAAGDEAAAAGEVAVELTLADWPAIEKEIAAAGKPVVVDIWSTACAPCMQEFHGLVELHDAHGEQVRCISVCIDYIGIKSKPPETYSDAVTAFLKSQKATTTNFLSTTADSDIYETLELDSIPAVFIYAADGTLTKRFVDAGDDAGFTYAKDVRPFVEQMLASE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXE7</accession>
    <name>A0A518IXE7_9BACT</name>
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        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
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        <name evidence="3" type="ORF">Mal33_37690</name>
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        <name type="scientific">Rosistilla oblonga</name>
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            <taxon>Planctomycetia</taxon>
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    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
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                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
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                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
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                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 4">Mal33</strain>
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005235">
        <property type="entry name" value="YmdB-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36303">
        <property type="entry name" value="PTHR36303"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13277">
        <property type="entry name" value="YmdB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004789">
        <property type="entry name" value="DR1281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="68"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="8"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
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        <location>
            <position position="39"/>
        </location>
    </feature>
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        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
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        <location>
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        <ligand>
            <name>a divalent metal cation</name>
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            <label>2</label>
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        <ligand>
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        <ligand>
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            <label>1</label>
        </ligand>
    </feature>
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        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR004789-51"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="QDV57755.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
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</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXQ2</accession>
    <name>A0A518IXQ2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Transcriptional regulatory protein ZraR</fullName>
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        <name evidence="9" type="primary">zraR_8</name>
        <name evidence="9" type="ORF">Mal33_38870</name>
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    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
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            <end position="380"/>
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            <position position="61"/>
        </location>
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        <source>
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        </source>
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        <source>
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        <source>
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        <source>
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        <source>
            <dbReference type="EMBL" id="QDV57872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="460" mass="50713" checksum="D4F03C0B92A803C6" modified="2019-10-16" version="1">MSKKTQPNAGLSIMFADDEPGLQELMAAELPRLGHTVTVCPDGLTALAAVEKQAYDCIIVDLDMPGMNGIEVLQRTKELQPLCEAIVLTGKSTTESAIIAVKCGAFDYLTKPSRLADLATLLGRVAERRQISKQMSALQLRLRRAEGDPQLIGKHPSMERVAKLIAKVAPTESTVLIRGETGCGKELVARAVHDRSRRAAESFVAINCGALPENLIESELFGHCRGAFTGADAARTGMFQVADGGTIFLDEIGELPLSMQAKLLRVLESREIRRVGDNQVEKIDVRVVCATHRNLEQMVEQGEFREDLMFRINTFEIEVPSLRERASDIPELAAHLLRRFNNEQLSDAELFTPETMSALTAHVWPGNVRELANVIEHAVILCDALPIRPEHLPRHFGDRQLRKELRSSGPMSLREMEHVAIEQALERHDGNKSAVAAELGISLKTLYNKLNTVAAEKQSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXU3</accession>
    <name>A0A518IXU3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">FG-GAP repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_39280</name>
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    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
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        <location>
            <begin position="30"/>
            <end position="794"/>
        </location>
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        <location>
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            <end position="740"/>
        </location>
    </feature>
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        <location>
            <begin position="431"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV57912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="794" mass="87372" checksum="E2AB60E23D2A8786" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IY28</accession>
    <name>A0A518IY28_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative protease YhbU</fullName>
            <ecNumber evidence="2">3.4.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">yhbU</name>
        <name evidence="2" type="ORF">Mal33_40030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.4.-.-" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="Pept_U32_collagenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001539">
        <property type="entry name" value="Peptidase_U32"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12392">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01136">
        <property type="entry name" value="Peptidase_U32"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF3656" evidence="1">
        <location>
            <begin position="403"/>
            <end position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="840" mass="92372" checksum="AB3A4E775F215F22" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IY59</accession>
    <name>A0A518IY59_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">PAAR motif protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_40460</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008727">
        <property type="entry name" value="PAAR_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05488">
        <property type="entry name" value="PAAR_motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="96" mass="9250" checksum="6044173CF8D8981C" modified="2019-10-16" version="1">MPCAARVADLHTCPMVTGLVPHVGGPISGPGAPTVLIGSLPASVVGDMCVCVGPPDSIVMGSATVMIGGKPAARMGDLTSHGGTITLGCPTVMIGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IY74</accession>
    <name>A0A518IY74_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histidine phosphatase superfamily (Branch 1)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_40510</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="SSF53254"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="186"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="208" mass="22317" checksum="CB97ECCABBD1C45F" modified="2019-10-16" version="1">MNRLNSRIEDQANRSTSVRTICQALFGLYVVLGTLNATPLFAQADPTDATTTFLVVRHAERDGNLDKLTKTGLQRSQILASLGIALNVQAIYSTDTQRTKGTVQPLATAAGTEIRIYETPSEDWIASLAHKHAGEVVLIVGHSNTAGVIAGMLAKGKHLELAHDEYDALFIIRVSASQTQSLRLRYGSSSDGASSADPDKMGTLVPAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYD2</accession>
    <name>A0A518IYD2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_41120</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021854321" evidence="2">
        <location>
            <begin position="17"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="48" mass="4850" checksum="69E350F261FC4E63" modified="2019-10-16" version="1" precursor="true">MRYVSLMLLLSLLSLAGCSSQLSVEETPVDPAAETPVEGGAGSSGDNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYE2</accession>
    <name>A0A518IYE2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Sensor protein ZraS</fullName>
            <ecNumber evidence="5">2.7.13.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">zraS_3</name>
        <name evidence="5" type="ORF">Mal33_41280</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.13.3" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028976">
        <property type="entry name" value="CheC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028051">
        <property type="entry name" value="CheX-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13690">
        <property type="entry name" value="CheX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103039">
        <property type="entry name" value="SSF103039"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0145">Chemotaxis</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="4">
        <location>
            <begin position="210"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="167"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV58111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="480" mass="52669" checksum="011DE4534263AB3B" modified="2019-10-16" version="1">MNDTKHLSDHAQTYEEIAERVFFEMFGISTLDRSDVIESNSLKTTKNFIVSIYYTGTVFGEYVIAMDESTAQRVIGLEGSLFEQTQDEVREMICDAISETLNTIVGEAIVQLQETHAKLTVTAPRVYFGEIRYPQFRTRSVTMQTQVGEIECYFCLDSMRLDLATSYDEAMESLVEINSKLKAANRHLAEQQAQLVHSEKMASIGILASGVAHEINNPLFFVDTNLNALCEYVHVIESTISDYERLCATLLDCNAPVIGSDGNELSLLDGKAPTSKQHRDIRYVLNDTKVLVSESRDGVIRIKDIVKSLKDFSNLDRGGIVDADLNAIVMNAVKMLQTTLGDTDKIEFQLGELATMACNVGEIAQVCSIVILNAVQATPNDGKVFVSTNGDEDESCLIVNDTGSGISAEDLAQIFDPFFTTKAEGEGTGLGLSIAYGIVRTHGGTINVESELGVGTKVIVRLPNESVQEELDEAECDAFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYF2</accession>
    <name>A0A518IYF2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">L-arabonate dehydratase</fullName>
            <ecNumber evidence="3">4.2.1.25</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">araC_3</name>
        <name evidence="3" type="ORF">Mal33_41270</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the IlvD/Edd family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.25" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050020">
        <property type="term" value="F:L-arabinonate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019752">
        <property type="term" value="P:carboxylic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044238">
        <property type="term" value="P:primary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="DiOHA_6PGluconate_deHydtase"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ILVD_EDD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="590" mass="64024" checksum="E3F5CEA7FF44CC53" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYG5</accession>
    <name>A0A518IYG5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Daunorubicin/doxorubicin resistance ATP-binding protein DrrA</fullName>
            <ecNumber evidence="6">3.6.3.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">drrA_1</name>
        <name evidence="6" type="ORF">Mal33_41520</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.6.3.-" evidence="6"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025302">
        <property type="entry name" value="DUF4162"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DUF4162"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="15"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="47"/>
            <end position="54"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV58135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="316" mass="34732" checksum="55A3C36A9B2DCA0D" modified="2019-10-16" version="1">MTSADPHHPTPQYAVEAVDVHHRYDDHVALDGVNLQIPQGKIFALLGPNGSGKTTLFRLLATLMPLQRGQLSVSGASVESVMEVRRRIGIVFQSPSLDKKLTVQENIRCQAALYGIHGAALRQREEEVLQRLRLADRRNDYCEKLSGGLKRRVELAKGMLHQPQVLLLDEPSTGLDPGARLDLWEALKEFSQQGLSVVLTTHLLEEAEKADQIAILSEGKVIAEGAPDRLRSQMGSGLITITTDQPEAVCQKLQQQMGIEGQALHNQVRIQSDQPGPMVPELLTTLGDQATSISIGRPSLEDVFIAKTGYQFWSGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYX5</accession>
    <name>A0A518IYX5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_42980</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="Ribbon_hlx_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014795">
        <property type="entry name" value="Vibrio_phage_ICP1_Orf50"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35401">
        <property type="entry name" value="PTHR35401"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08681">
        <property type="entry name" value="DUF1778"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47598">
        <property type="entry name" value="SSF47598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="93" mass="10306" checksum="6E9C482E97100403" modified="2019-10-16" version="1">MAKSLKTERIEARVEPSVRKLIVAAAQLEGRSVSEFLVASAKERAEAALYRQTVIRLTAEDQLRFAEAILDPPPLNDAMHEALALHEQLIDPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYZ4</accession>
    <name>A0A518IYZ4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Phosphatidylserine decarboxylase proenzyme</fullName>
            <ecNumber evidence="5">4.1.1.65</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">psd</name>
        <name evidence="5" type="ORF">Mal33_43170</name>
    </gene>
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        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="4.1.1.65" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004609">
        <property type="term" value="F:phosphatidylserine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003817">
        <property type="entry name" value="PS_Dcarbxylase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10067">
        <property type="entry name" value="PTHR10067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02666">
        <property type="entry name" value="PS_Dcarbxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="3 5" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0865">Zymogen</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV58299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="297" mass="33282" checksum="8460908AE56E76D8" modified="2019-10-16" version="1">MDEIVYYDRYRKENCVEKVYGDKALRWTYGTVAGRISLNLLVKRALFSHWYGWRMDRPATRQKIPAFIQDYQLDASEFARDVDEFANFNEFFFRELKPSARPIDPDPAAAVFPADGRHLCIPDLSQADGLFVKGETFDLGSLLKDPALADRYANGSLLLSRLCPVDYHRFHFPAAGVPGPTRLINGPLYSVNPIALCQNIQILATNKRCITELETEAFGTVLVLEIGATCVGSICQTYTSGTEVAKGSEKGYFRFGGSSTITIFPAGRIRFDQDLIENSQQQRELYARVGDHLGTAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ26</accession>
    <name>A0A518IZ26_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_43490</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
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                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010415">
        <property type="entry name" value="LpxI_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043167">
        <property type="entry name" value="LpxI_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041255">
        <property type="entry name" value="LpxI_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06230">
        <property type="entry name" value="LpxI_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17930">
        <property type="entry name" value="LpxI_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LpxI_N" evidence="2">
        <location>
            <begin position="21"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="LpxI_C" evidence="1">
        <location>
            <begin position="164"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="309" mass="33739" checksum="E1A5C076FEAC814C" modified="2019-10-16" version="1">MNSAILSSPPTASASQSGSTVGLIAGWGRFPILVAESLKRQNHRVACAAIRGHACESLNDICDEVRWFGVAKMGGQLRFFRRHGVQRMTMAGKLFKADLMFQGSVWLRHLPDLFCIRTMAPHFITRRKDTRDDTLLTAVTDAYLARGIEVCPATDFAPELLVKQGHHSTQRLNNKQQADVRFGWTIAKQMGGLDIGQSITVKDQTVVAVEAVEGTDACIERSGNLCGKRGFTLIKVAKPQQDMRFDVPTIGPQTIELLAAAGGECIVIEADKTIVVDQDEVTRIANAHRIAIVAVNDADLAENENIFAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZN1</accession>
    <name>A0A518IZN1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GIY-YIG nuclease superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_45640</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000305">
        <property type="entry name" value="GIY-YIG_endonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035901">
        <property type="entry name" value="GIY-YIG_endonuc_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01541">
        <property type="entry name" value="GIY-YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82771">
        <property type="entry name" value="SSF82771"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50164">
        <property type="entry name" value="GIY_YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GIY-YIG" evidence="2">
        <location>
            <begin position="21"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="112" mass="12402" checksum="D842F3AC9FBB0D53" modified="2019-10-16" version="1">MSKSPPISSPSNDAESPRDQPPWFVYILRCGDGSFYTGITKDVDRRLKQHNAGKASRYTRSRLPVEIIYREVQPDQSAALKRELAIKALSRPAKQSLIASDSNRLGEAKSAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZP8</accession>
    <name>A0A518IZP8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Inositol 2-dehydrogenase</fullName>
            <ecNumber evidence="4">1.1.1.18</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">iolG_15</name>
        <name evidence="4" type="ORF">Mal33_45850</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.1.18" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050112">
        <property type="term" value="F:inositol 2-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043906">
        <property type="entry name" value="Gfo/Idh/MocA_OxRdtase_bact_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19051">
        <property type="entry name" value="GFO_IDH_MocA_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021917641" evidence="1">
        <location>
            <begin position="30"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="domain" description="GFO_IDH_MocA" evidence="2">
        <location>
            <begin position="40"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="GFO_IDH_MocA_C2" evidence="3">
        <location>
            <begin position="201"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF19051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV58562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="430" mass="47236" checksum="0E83CF3B9891D481" modified="2019-10-16" version="1" precursor="true">MQAARPTRRTALKTSVAFGGYLIAPEVSAAESTSANEQLNIACIGIGGRGAANVNGVKSQNLVALCDVDQQRAGKVFEQHNQAEKFADYRKMFDKLEKQIDAVVVSTPDHTHFHPSMAAMERGKHLYCEKPMAHSVGEVRQMTKMAVKQGVATQLGCQRHALANMHRSVELIQAGAIGDVSEVYSWVGGSRGMPSIPKTFPKVPETVDWDLWLGPAMPRPYDSTYCPYGWRFWWDFGTGETGNWGCHILDIPFWALGLKYPSRVEGSGPEVDDQRTPKQMATKMHFAEQGVDLHWDHASAGPAKLKELGIDGKGMNTLFIGTKGMLLTGFNKLRLLPEEKFADFKAPEPTIPKSPGFYKEWISACKGGEPATCDFRYSGPLAETVLLGNAAYRASGSFDWDGPSLTASGNDAVQPFLKSEYRKGWEVAEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZS9</accession>
    <name>A0A518IZS9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_46160</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="52" mass="5511" checksum="F3B63FE02C9C3789" modified="2019-10-16" version="1">MQIIVAPLVAINDVGLSHWGQEAFRTAAVRGCPPRLDSAAVPNWLLAIEAGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZT1</accession>
    <name>A0A518IZT1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">D-galactonate dehydratase</fullName>
            <ecNumber evidence="2">4.2.1.6</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">dgoD_2</name>
        <name evidence="2" type="ORF">Mal33_45680</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
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    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008869">
        <property type="term" value="F:galactonate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR029017">
        <property type="entry name" value="Enolase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029065">
        <property type="entry name" value="Enolase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013342">
        <property type="entry name" value="Mandelate_racemase_C"/>
    </dbReference>
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        <property type="entry name" value="Mandelate_racemase_DgoD-like"/>
    </dbReference>
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        <property type="entry name" value="Mandelate_racemase_N_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48080">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00922">
        <property type="entry name" value="MR_MLE"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF51604"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF54826"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MR_MLE" evidence="1">
        <location>
            <begin position="155"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="406" mass="44666" checksum="35F3C78CD86E1541" modified="2019-10-16" version="1">MILASQDFSSRKNNMKITAIETHVCHARMRNWIFVKVITDQPGLVGWGEATLEWHTRGVVGSIQDLSELLIGEDPTSIEHLWQMMWRQHFWHGSGVVRSTAISGIDLALWDILGKVHGVPCHRLWGGPVRDSIRMYCHLGGGNLESFYETPVDNARQFADLAQQAVDDGFSAFKSMAVPPTMPVEGLKAIKAADACVAAMREAVGDDIDIMVDCHARPSPAMGMQFAKALDQYGLYFFEEPCWPESLDSLAAINAAVTTPIATGERLTHLAAFRDLFAARGCEICQLDLTHCGGFTEARRIAALADAYRIALAPHNPQGPISTAASLEFGFSQPSYIICEAVHQDVPWRSDVVQESYVVDEATRTVTAGTAPGLGVTVDEDEIRKHPFQQELPQRVFYPDGAVGDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J039</accession>
    <name>A0A518J039_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_46790</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="90" mass="10660" checksum="B14FF968682450A8" modified="2019-10-16" version="1">MRELLRRAMQQSDDLVVEMDYMDCHGRHTRRVISPIRFTSSEHFLALCLCREEPRNFNLSRCRNPRLRWAADVVMPVEFAEPMQPVGARN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J045</accession>
    <name>A0A518J045_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Helix-turn-helix protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_47410</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="10"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="125" mass="13728" checksum="9C5F093786342B6F" modified="2019-10-16" version="1">MPLHEIVARIQERKRELDISVSDLARRSGVSRATVIRILGGEDHEFSFANLQAILLALGISLDLTEIPAEQFRDQIATAKAKRLIALTQGNVALESQAVSRASAQSHLEEAKARIEASSRKLWAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J074</accession>
    <name>A0A518J074_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Arylsulfatase</fullName>
            <ecNumber evidence="6">3.1.6.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">atsA_32</name>
        <name evidence="6" type="ORF">Mal33_47710</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="PTM">
        <text evidence="3">The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the sulfatase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.6.1" evidence="6"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004065">
        <property type="term" value="F:arylsulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024607">
        <property type="entry name" value="Sulfatase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00149">
        <property type="entry name" value="SULFATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase" evidence="5">
        <location>
            <begin position="60"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="modified residue" description="3-oxoalanine (Cys)" evidence="3">
        <location>
            <position position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR600917-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV58746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="933" mass="102905" checksum="2102497ACE649A47" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J096</accession>
    <name>A0A518J096_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Nickel/cobalt efflux system</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rcnA</name>
        <name evidence="8" type="ORF">Mal33_47500</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the NiCoT transporter (TC 2.A.52) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015099">
        <property type="term" value="F:nickel cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011541">
        <property type="entry name" value="Ni/Co_transpt_high_affinity"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03824">
        <property type="entry name" value="NicO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0533">Nickel</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="46"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="89"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="140"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="173"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="215"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV58725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="236" mass="25296" checksum="FCBB47C71A75FF4A" modified="2019-10-16" version="1">MHQHTHELTLGVAFFLGALHALEPGHGKTAMLVYLSGERRSYWHPLVMGLSSGLAHSVSLIAIAMAVHLTHHLITGDHHHDNEAMTATLQWISAGLVLCVGTWMLWAAYRAKPAKKCGCRHHRDEDCDAKPRSAKSSYSMSALLGVAFGLLPCPSALAAYFTSMSTGSPVAAYAVIGLFAAGIASSLTCVGMLLQRFGGSLIREESRLAKLPWNYVRAILILGVGVFYAARVAMAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0E6</accession>
    <name>A0A518J0E6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Phosphoribosyl-ATP pyrophosphatase</fullName>
            <shortName evidence="8">PRA-PH</shortName>
            <ecNumber evidence="8">3.6.1.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8 9" type="primary">hisE</name>
        <name evidence="9" type="ORF">Mal33_48350</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>1-(5-phospho-beta-D-ribosyl)-ATP + H2O = 1-(5-phospho-beta-D-ribosyl)-5'-AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22828"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:59457"/>
            <dbReference type="ChEBI" id="CHEBI:73183"/>
            <dbReference type="EC" id="3.6.1.31"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 2/9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the PRA-PH family.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.31" evidence="8"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00007"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004636">
        <property type="term" value="F:phosphoribosyl-ATP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd11534">
        <property type="entry name" value="NTP-PPase_HisIE_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01020">
        <property type="entry name" value="HisE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008179">
        <property type="entry name" value="HisE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021130">
        <property type="entry name" value="PRib-ATP_PPHydrolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01503">
        <property type="entry name" value="PRA-PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03188">
        <property type="entry name" value="histidine_hisI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 8" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="5 8 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV58810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="117" mass="12824" checksum="04586572EC305412" modified="2019-10-16" version="1">MSEALTILNRLMETIQDRASQRPEGSYTTKLIEGGAPRIGKKVIEEAAEVVEAAAESGEEGKQHFTYEVGDLLYHVMVMMAWRGVTLDDVAAELGRREGIGGLVEKAQRSQSTDDTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0M5</accession>
    <name>A0A518J0M5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Abhydrolase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_48800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025890">
        <property type="entry name" value="Abhydrolase_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12715">
        <property type="entry name" value="Abhydrolase_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="454" mass="50651" checksum="F65E129F82E22CFB" modified="2019-10-16" version="1">MTRTYLPMRRIASSRPVATAVWMFALVMPALGQKLDIEKESVIRSGRADGRHLSTRGFQQYLLRNAQPKLAFDPEFTSDEFAQWQSQVRAKLLELMNFPEPVAQPEPRRLWIRKREGYVLQKWELYPEPGSVVPFLVLVPNSATSANPAPAIMCIPGSSGTKENLAGEPPLGPAFKPDDRNHDGWLHAQRNQQAVQFARAGFVAVAVDHPGTGELSDLARYRGTTMDDRNTISRYLIDMGRSFIALSVFQKLQILDWLREQSHVDAQRVAVSGHSLGTEALLALAVLDPQIQGVVWNDYLAATRERARASTKPNHRGIRPGANWLGHSVPGLWQWFDYPDLVAAIAPRPLLVTEGGPSHSLNLVQKAYQIAGAADNVSIHYYPQYHDSANRRDGKPIPEGLSSTEWLDYANVHAAHHYFKGYLAIPWLTGQFQLPDPGEVYPPAPPEAVKTLLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J100</accession>
    <name>A0A518J100_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_50460</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="68" mass="8077" checksum="A3ABE01F9B8BFA58" modified="2019-10-16" version="1">MSREEFEQWVAKHPWKLQPYDMSFVDHDSKRLDFTAPDFAYATEMASNGGQLRVYFKDGVMYLSYNVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J119</accession>
    <name>A0A518J119_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_50610</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="252" mass="29132" checksum="971E1AA78085ADE3" modified="2019-10-16" version="1">MFGWFKPHCPVDVATKRWVENRLQWLSREFGRDTFTRRAVILPTNDFFPDPMDGTEASVRNLLDQVCGYMDVNPSRVELELFTNKNELWLVNDDGKYLPTGAAGLYDEQIGKTVIHIETSEMMDLSGLVGTMAHELSHLRLMGERRVTGDEYDNELLTDLTAVFHGFGIFLGNSPRNWDSQYSVWPGTDIKRPEYMTLPMFAYALAHTAWFRGQRKPDWLPFLSFDLRPCFKQGVRYLMETRDSTFAPENLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1C6</accession>
    <name>A0A518J1C6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Outer membrane efflux protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_51680</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021711361" evidence="4">
        <location>
            <begin position="31"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="89"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="483"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="98"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="123"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="154"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV59140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="579" mass="63057" checksum="7EE20E60F6E5A5B0" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1G3</accession>
    <name>A0A518J1G3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_52000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="34"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="66"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV59172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="92" mass="10206" checksum="E5A1CCB7F8DDDB08" modified="2019-10-16" version="1">MESAAEWQSRHAPSDRGAGEGERHRDARLRHYRFFFLVVFLAAAFTATFLVAVFLVAAFFVPRAVATFLVAFFVAAFFVALPLLNALLQPSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J247</accession>
    <name>A0A518J247_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA</fullName>
            <ecNumber evidence="2">3.1.4.17</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">cpdA</name>
        <name evidence="2" type="ORF">Mal33_54430</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.4.17" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004114">
        <property type="term" value="F:3',5'-cyclic-nucleotide phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos" evidence="1">
        <location>
            <begin position="43"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="308" mass="33762" checksum="D500D0950F816A04" modified="2019-10-16" version="1">MPIHKIPQSRRRFLQTTVVGGGAALLMSSTQRLSAAEADATVIALLSDTHIPSSHDVEARGINMTDNLQRVIGEVVARKTRPTDLIINGDCAYLKGLPGDYQNLVSCLAPLDRAGISLHLTMGNHDDRQPLYDALSDQRPADAQVTAKHVSVIETPHANFFLLDSLFRVNVVTGEIGAAQIQWLAKQLDARADKPAIVMTHHTPQFTAPAEGKPWTGISDTAALMAVLDSRKHVKAYLYGHSHHWNHSQRGHFQMINLPPVAYVFNDKSPNGWVEAVLTPGEMRLELQTLDPKHPLSGEVVTVALNRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J295</accession>
    <name>A0A518J295_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_54930</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59458.1"/>
        </source>
    </evidence>
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            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J2B3</accession>
    <name>A0A518J2B3_9BACT</name>
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        <submittedName>
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        </submittedName>
    </protein>
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    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
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                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 4">Mal33</strain>
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    </reference>
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            <end position="22"/>
        </location>
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            <end position="783"/>
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            <end position="435"/>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="QDV59476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="783" mass="84155" checksum="100ABBF9D1930C00" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
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    <name>A0A518J2B9_9BACT</name>
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        <submittedName>
            <fullName evidence="8">Sodium/proline symporter</fullName>
        </submittedName>
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        <name evidence="8" type="primary">putP</name>
        <name evidence="8" type="ORF">Mal33_55210</name>
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        <name type="scientific">Rosistilla oblonga</name>
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        <lineage>
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            <taxon>Planctomycetia</taxon>
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    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
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                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
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                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
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    </reference>
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            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
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        <property type="project" value="UniProtKB-KW"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="NA_SOLUT_SYMP_3"/>
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    </dbReference>
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    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="37"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
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            <end position="98"/>
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    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
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            <end position="146"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
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            <end position="187"/>
        </location>
    </feature>
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    <feature type="transmembrane region" description="Helical" evidence="7">
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            <end position="508"/>
        </location>
    </feature>
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        <source>
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        <source>
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        <source>
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            <dbReference type="SAM" id="Phobius"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="QDV59486.1"/>
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        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="526" mass="56247" checksum="2DB7B100AE788B7D" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J2G2</accession>
    <name>A0A518J2G2_9BACT</name>
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    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
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                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
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                <person name="Overmann J."/>
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                <person name="Ovreas L."/>
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                <person name="Galperin M.Y."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
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    <dbReference type="EMBL" id="CP036318">
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="project" value="InterPro"/>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
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    </dbReference>
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    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="619"/>
            <end position="697"/>
        </location>
    </feature>
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        <location>
            <position position="657"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV59525.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="709" mass="76754" checksum="372B7DEA8405E44C" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ILX1</accession>
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    </protein>
    <gene>
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        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 3">
            <text>H(+) + meso-2,6-diaminoheptanedioate = CO2 + L-lysine</text>
            <dbReference type="Rhea" id="RHEA:15101"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:32551"/>
            <dbReference type="ChEBI" id="CHEBI:57791"/>
            <dbReference type="EC" id="4.1.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 2 3">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 3">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; L-lysine from DL-2,6-diaminopimelate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.20" evidence="2 3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00027"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008836">
        <property type="term" value="F:diaminopimelate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06828">
        <property type="entry name" value="PLPDE_III_DapDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.37.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02120">
        <property type="entry name" value="LysA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009006">
        <property type="entry name" value="Ala_racemase/Decarboxylase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002986">
        <property type="entry name" value="DAP_deCOOHase_LysA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022643">
        <property type="entry name" value="De-COase2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022657">
        <property type="entry name" value="De-COase2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022644">
        <property type="entry name" value="De-COase2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000183">
        <property type="entry name" value="Orn/DAP/Arg_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02784">
        <property type="entry name" value="Orn_Arg_deC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00278">
        <property type="entry name" value="Orn_DAP_Arg_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01181">
        <property type="entry name" value="DAPDCRBXLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01179">
        <property type="entry name" value="ODADCRBXLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50621">
        <property type="entry name" value="SSF50621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="SSF51419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01048">
        <property type="entry name" value="lysA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00879">
        <property type="entry name" value="ODR_DC_2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2 3" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="2 3 6" id="KW-0456">Lyase</keyword>
    <keyword evidence="2 3" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Orn_DAP_Arg_deC" evidence="4">
        <location>
            <begin position="30"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="domain" description="Orn_Arg_deC_N" evidence="5">
        <location>
            <begin position="50"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="2">
        <location>
            <begin position="270"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="229"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="273"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="309"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="313"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="343"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="378"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="2">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV54063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="422" mass="46289" checksum="303E8CD0868FC91E" modified="2019-10-16" version="1">MTITTNFATSRTEIAGHSITDLANQFGTPLYVYDSAVIAQRVADLQMFDDIRYAQKALSNIAILDRLRKQNVLVDAVSAGEIHRALAAGYEPHGEGHPIVYTADIFDREALELVKKHGIHVNCGSPDMIDQLGEVVPGADITLRINPGFGHGHSQKTNTGGPQSKHGIWHGDLDECQRRADRYGITITGLHMHIGSGTDLEHLSKVCDSMRDAALSVGRTITTISAGGGLPVRYKKEETYVDLAAYYKLWNTVREELQTKFDHAVRLEIEPGRYLAAECGYLVTEIRAIKNMGENMFYLVDAGFNDLARPILYGAHHPISICSRSGAGDRPLVNVVVGGPLCESGDIFTQEEGGFVSHRELPRAEVGDLLILENAGAYGFVMASNYNSRLRASELLLEDGQAKVIRNRETFEQLLASETIPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ILX6</accession>
    <name>A0A518ILX6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_00400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="59" mass="6499" checksum="A8AC4F85EC773CFC" modified="2019-10-16" version="1">MSAVTASTRPSNLSILIRFTRRIGLRFIGTIDRVERQMRRSGAVVSSSAGQPIVLIAKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IM51</accession>
    <name>A0A518IM51_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SGNH_hydro domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_01030</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021989957" description="SGNH_hydro domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="SGNH_hydro" evidence="2">
        <location>
            <begin position="39"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="217" mass="24103" checksum="E925D627265AFF0B" modified="2019-10-16" version="1" precursor="true">MHRICCIALLSLVCSPSVFGQQGVLKPIEDRADLPRVLLIGDSISMGYTVPTRKLLADKANVHRIPANGGPTTRGLANIDKWLGDGDWDLIHFNWGIHDLKHQADGTRQVEPAAYEKNLRALVAKLKATGAKLVWASTTPIPKGKLNPDRTFGDETHYNEIAARVMTELDVPINDLHGYVMPRFDELHRPQDLHYTSAGSDFLAERVADVIEQHLSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMP9</accession>
    <name>A0A518IMP9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GDSL-like Lipase/Acylhydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_03200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022054614" evidence="1">
        <location>
            <begin position="23"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="domain" description="SGNH_hydro" evidence="2">
        <location>
            <begin position="50"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="471" mass="52129" checksum="79756DEE4701CA8C" modified="2019-10-16" version="1" precursor="true">MRLRNIALFTACILLSSQSTDADSPQTVTPEAKPPAIPATPFADGERVCFLGDSITAGGYVQTLIADYYLTRFPERTVHFFNAGRSGDTASGSLSRLKEDVIDKRPTSVVIMFGMNDVSRGSYTANPTDAQKVRQQQALGRYKAKMEEVVARLRDEANNPKLYFMTPSPFDQTVVLDRDNNQPGCNDGLGRCAAIVRQLALENNAPVIDLHGPMTALNLQQQKLDPTWTIVGPDRVHPGSPGRLMMAWLFLKAQGVPATISRTTIDAAAGKVAESVNAEVESVERIEEGVKFMSREQALPFPINASPMELFDLLPIGDDLAQQILSVTGLSEGTYELRIDGAAVGQYQAADLASGLNLAFNKATPQYKQARRVAELNSQRRNAEATACSLLNTRRWMQSYYKVDVDDPKAVQAHYDHFEDKKQYSAVMARRYMEEWPKYSEFRKRAAELQQAAEASREPVAHTFELVRISG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMZ2</accession>
    <name>A0A518IMZ2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ankyrin repeats (3 copies)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_03860</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="SSF48403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="185"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="357" mass="40405" checksum="8E6D9AC682D7FF38" modified="2019-10-16" version="1">MRTKTLLILSVLILCFIGCDRAIESLTTRPPSDGSIHDDKTNRWNDRSFHDIIRAGGRHRSDRIKELIAEGGDLNELDHNGNTPAVLATGWGGQYDIAIMLVSAGAEYDIYKRNSNHRLAHFVVMEERRAGLWSPEQRRDHARLIKLLETRGESFTEVRADFARWKELYAGTSLSQYAKLRDQEIAEREARSTGNAGPTNKTSQSGSKITVQSPDALHQLIDQRAKGCDDCVQRIRELIAEGFDVNAISSWGMPAVIWAVDKGRQFDVALLLLRNGADPSVPCINQKTGNPLRLKLIHYVERAADDIQMYDKQQRQDYEELVTWLTDHGESIEQAKQERHFWNQPLVEPPPADLNAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IN82</accession>
    <name>A0A518IN82_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_05130</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021796">
        <property type="entry name" value="DUF3365"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11845">
        <property type="entry name" value="DUF3365"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="185" mass="20498" checksum="30C182F51F0B9E51" modified="2019-10-16" version="1">MKYRVTAFGVFFAIGCSLLTLRAEQPEAAADPAAKRVAVASSLAEARSRATLLHETIHGTLQVVHRDLFDEDDAHTIPSASLEDVFHAMADSFQVEMKWLVVNTDVVNVDHRPEDEFEHAAVKALAAGKPYFDRVQEDRYRFAGSIRLASQCLKCHVKHRTSTHDRTAGLLISMPLKLDAAATQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IN98</accession>
    <name>A0A518IN98_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_04970</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="83" mass="9440" checksum="A7AC4B860FB69879" modified="2019-10-16" version="1">MIGLTDTKKLLSLVLAIAGVAVVWLVILPAYARQPAMTKHLQWLDDQGIDPSAMYYTELEVMEQILQRQRAEQLLDKASDEQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IND0</accession>
    <name>A0A518IND0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Lipoprotein signal peptidase</fullName>
            <ecNumber evidence="6">3.4.23.36</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Prolipoprotein signal peptidase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Signal peptidase II</fullName>
            <shortName evidence="6">SPase II</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 9" type="primary">lspA</name>
        <name evidence="9" type="ORF">Mal33_05460</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">This protein specifically catalyzes the removal of signal peptides from prolipoproteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>Release of signal peptides from bacterial membrane prolipoproteins. Hydrolyzes -Xaa-Yaa-Zaa-|-(S,diacylglyceryl)Cys-, in which Xaa is hydrophobic (preferably Leu), and Yaa (Ala or Ser) and Zaa (Gly or Ala) have small, neutral side chains.</text>
            <dbReference type="EC" id="3.4.23.36"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6">Protein modification; lipoprotein biosynthesis (signal peptide cleavage).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the peptidase A8 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.23.36" evidence="6"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00665"/>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00161">
        <property type="entry name" value="LspA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001872">
        <property type="entry name" value="Peptidase_A8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33695">
        <property type="entry name" value="PTHR33695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01252">
        <property type="entry name" value="Peptidase_A8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00781">
        <property type="entry name" value="LIPOSIGPTASE"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="2 6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="45"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="82"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="107"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="132"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="212"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="171"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV54591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="233" mass="25572" checksum="3E066A7C7CFB87F3" modified="2019-10-16" version="1">MLSPNGDPQVLANAPADRSNPPPQSRDGSPLPHSNPLPAIPTNRYITFFALAILGAVADLWTKQAMFAWRGLPGMRPPHWVVEGYVGIETAVNIGAVFGIGAGKGQLFAAISVVAAIAIFIWLFVKRAAHQWLLTIALGCVMGGIIGNLYDRLGLWWEPGMDPRWQSGVRDWILFQASDTLKWPNFNIADSLLVCGAAMLIYRSFFPVDEFDDDKPNSQEDSNEAHRDNNSSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IND7</accession>
    <name>A0A518IND7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_05400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="152" mass="16227" checksum="6B4CA29128389C7B" modified="2019-10-16" version="1">MTDPRRFVDSTNTKINSILVTKFVAIVLLLASVGCVGSGLVMPETGEVEGIVTMDGQPLPNVSIVFQPQENPQARASMAVSDEQGRYTLTYHTDKQGALIGMHTVSITTPTDAPDPSGQSKDPIPARYNSQSELVVEVKAGSNDIPLELTSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INM5</accession>
    <name>A0A518INM5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_06510</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="55"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="416"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="60"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="94"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="150"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="178"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV54694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="602" mass="65921" checksum="F1018BBCFE00B519" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INQ9</accession>
    <name>A0A518INQ9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_06750</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021717921" evidence="1">
        <location>
            <begin position="23"/>
            <end position="511"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="511" mass="54895" checksum="6F590D6CB8C6D901" modified="2019-10-16" version="1" precursor="true">MNRSLLLLSLVLSLLAVSKSDAQFEGMKYRIPADANTLILINAEKAFGSPVSDRERWAARRKAAYDAGVSALPPDATEVILAGRSDLEYGKSVWELALMKLTGERNVATVATRFGGSIDNIAGRSAARLPDDHYVVQIRSDLMGAYTPANRQDVSRWLKSTDLDTGQKMSPYLQHAFAFAAEVGTPIVMAMDLSGLVSEAAVTRKLPELGSLKDSGLSPAAVSKLIGGVQGIMLGITLEDQTIGAVRVDFEASPEILAKVGKPLLIEILSSQGAMIDDIRQWTPSVKGNTFFLRGKLSASGTRRVMSVLELPRSLGEAVNDAASSGADSEESAARIASQQYFKSVSTLLDDLRDKPKTDHVKTFGQAAIWYDKYARKIDSLPLLNVDPALLKYGSDVSGMLRDAEMSMKGVGMRSSVRTGMNSPTSYGYSSYGGGYRAGRGYDGALYGPQGYSASVGAAQASVREEGRTDAVIRGQERTKGAASVQQIWQDIDSATAEIRQVMTGRYSAEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INS4</accession>
    <name>A0A518INS4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_06950</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010869">
        <property type="entry name" value="DUF1501"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07394">
        <property type="entry name" value="DUF1501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="439" mass="47878" checksum="9191CB17339CEA12" modified="2019-10-16" version="1">MTRYQNCSGVTRRNCLQVGLGGFFSLGLSGALRAADASRLIKQHQADACILVWQDGGPSHYETFDPKPDAPVEIRGEFGTIPTAIPGVRFSQHMKATAKIADRLSIVRSIRHDQGNHGAGNHYMMTGSPPRIPVGCGAFVSFHPSMGSVVSAEVGAPAGMPAYFSMPSMSRSGGPNFLGAKYAPFVVPDNPNSDNFQVRDVALPKGLSEAKFSNRQSIRQQIDALKRFRDEAAADPLVAVDEFYDQGQQLMTSPQAQKAFDIHSEPEETRAKYGRNSFGQRALLARRLVEAGVPFITLYEGGWDHHRQLFSAFDKKLPPHEQTIAALIQDLEERGMLERTLVIVLGEFGRTPKINKDGGRDHWANAMSVMFAGGGTPGGQVIGATDRQGHSAVDRVLAPENFVSTVYRKLGIDPNKIVHTPEGRPVTYVTNPEPISELM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP02</accession>
    <name>A0A518IP02_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_07980</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="184" mass="20958" checksum="C0FDDB3CC3E88060" modified="2019-10-16" version="1">MTQDDGNRAVALVVALLNRIALPYMLVGSYSSNVYGIPRATADADFVLEFGGNAMDSLQQELGSDFRLDSQTEFELITGTTRRVLYYLPRDFTIELFQLSQDPFDQSRFQRRVAVQSSLLAGVVWLPTAEDVVVQKLRWGRRQDLSDVSDVLAIQGETLDWRYISRWTDDHGTSDMLERIRSEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP25</accession>
    <name>A0A518IP25_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_08120</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="148" mass="16526" checksum="BFDEA76CC1DE1E27" modified="2019-10-16" version="1">MGHAVKMLFVIFVVAMFPKLGCAQTLGGEISKMTQQLVSFLNDEGHDAVFLGSFDRQFETEMGRDIHRQFEEQLIANSIVVLEEPGSLQLLGDFTVCEQTMHSIVTLKVEVRNSQGRVLNQYRKRVKVLHASSDATVVAVVRNGSLYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP76</accession>
    <name>A0A518IP76_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Adenosylmethionine-8-amino-7-oxononanoate aminotransferase</fullName>
            <ecNumber evidence="4">2.6.1.62</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">7,8-diamino-pelargonic acid aminotransferase</fullName>
            <shortName evidence="4">DAPA AT</shortName>
            <shortName evidence="4">DAPA aminotransferase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">7,8-diaminononanoate synthase</fullName>
            <shortName evidence="4">DANS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Diaminopelargonic acid synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">bioK</name>
        <name evidence="4" type="synonym">bioA</name>
        <name evidence="6" type="ORF">Mal33_08680</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>(8S)-8-amino-7-oxononanoate + S-adenosyl-L-methionine = (7R,8S)-7,8-diammoniononanoate + S-adenosyl-4-methylsulfanyl-2-oxobutanoate</text>
            <dbReference type="Rhea" id="RHEA:16861"/>
            <dbReference type="ChEBI" id="CHEBI:16490"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:149468"/>
            <dbReference type="ChEBI" id="CHEBI:149469"/>
            <dbReference type="EC" id="2.6.1.62"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 4">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Cofactor biosynthesis; biotin biosynthesis; 7,8-diaminononanoate from 8-amino-7-oxononanoate (SAM route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.62" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00078">
        <property type="reaction ID" value="UER00160"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004015">
        <property type="term" value="F:adenosylmethionine-8-amino-7-oxononanoate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009102">
        <property type="term" value="P:biotin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00834">
        <property type="entry name" value="BioA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005815">
        <property type="entry name" value="BioA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000521">
        <property type="entry name" value="Transaminase_4ab_Lys_Orn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00508">
        <property type="entry name" value="bioA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="4" id="KW-0093">Biotin biosynthesis</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 4 5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="4">
        <location>
            <begin position="118"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="4">
        <location>
            <begin position="324"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="153"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="259"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="288"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="323"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="418"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM" evidence="4">
        <location>
            <position position="24"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="4">
        <location>
            <position position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV54903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="455" mass="50155" checksum="E80FBDB029C15E17" modified="2019-10-16" version="1">MTTKNTYSNADIAHIDRTAVWHGFTQMAHYEPLVIERGEGNWLFDIEGRRLLDGVSSLWCNLHGHNHPTINAAIRDQLGKIAHVTSLGMIGRTAVELTGRLVDVTPEGLNHVFYSSDGSSSVEAALKMAFQYWQQRENPQPQKTKYVAMGAAYHGDTTGGVSLGGVEHFHSLFGPLLFDVLRGPCPDTYRLPENVTPETACDHYFETFRDLVTGQHQQIAAVVMEPLVQGAAGMVMHPEGFLRRVRDLTRELDILLICDEVATGFGRTGKMFACQHEQVSPDLMCIAKGLTGGYLPMAATLASDAVWNAFLGDLDQNKQFFHGHTYSGNPMAAAAGLASLDVFEEEQVLENLPAKIDHLERCLQPLASHRHVGSIRQRGLMVGIELVEEKASKQPFPAGQTRGARVCRHALDRGVWIRPLGNVIVLMPPLSIQADEIETLVEAVRYGISQEFPGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPN9</accession>
    <name>A0A518IPN9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_09980</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021810016" evidence="1">
        <location>
            <begin position="19"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="146" mass="15282" checksum="82A52626C81E361C" modified="2019-10-16" version="1" precursor="true">MARIIFCCALAAGTLVLAGCGDDVTTTVASGTVRTDSGTPCDGALVVFHPQESERINDPKPVATCDDQGKFTLTTFQKDDGAEPGKYGVTVVWQAKVKAGRLSLSSESEPVGKDQLKGKYGKPASPLLTAEVTAGSPNTFEFIVEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPT9</accession>
    <name>A0A518IPT9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">15-cis-phytoene desaturase</fullName>
            <ecNumber evidence="2">1.3.5.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">pds</name>
        <name evidence="2" type="ORF">Mal33_10850</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.3.5.5" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017830">
        <property type="entry name" value="SQase_HpnE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03467">
        <property type="entry name" value="HpnE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amino_oxidase" evidence="1">
        <location>
            <begin position="15"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="465" mass="50435" checksum="FBE28A16A0B14525" modified="2019-10-16" version="1">MESSSPRVAIVGAGLAGMAAALGLSQSGFKVSLIEARSRTGGRAGSFTDPTTGAEIDYCQHVGMGCCTNLIDLLQQTGQLDDWRRYRSLMFIGPTGEVCPFAGSRWLPAPLYLMKAFSGLSYLSQDLRKTIAQGIWKLMRLRPEDQANWPTMQDWLTAAGQSEAAIREFWDVILVSALGEATDRVAVAPARKVLVDGFLSHRDAGDVWVPQLPLSVLFGQRLPDDLTRRGVEIRLSARAVGIESHGGRATGVRLSDGSTVAADCVLIATPWHQLTNVLGDASVLVDASDAVASIPASPITGIHLWCDRPLTAEPHLVFVGRTIQWLFRPTFASDQPSRIYHQIVISGSRDLPPRQQLLDEVIGELRELLPAARDATVVDSRIVTDPNSVYSVSLATEKRRPAATTRLPNLWLAGDWTATGWPATMESAVISGYRAADQIADNLGRPSGNEQPALAKSWLARLLIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQ32</accession>
    <name>A0A518IQ32_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative polyketide biosynthesis zinc-dependent hydrolase BaeB</fullName>
            <ecNumber evidence="2">3.-.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">baeB_1</name>
        <name evidence="2" type="ORF">Mal33_11520</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.-.-.-" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="23"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="267" mass="29923" checksum="77357865010F21B7" modified="2019-10-16" version="1">MLPHKTLFPGVIELNFQAGEVLGCNVYLVHDQGEWTLIDIGYEETVDEFIELIRQLDFPLSKCKTLIATHADVDHIQGLAKAKQMLRTSVTSHPLAVEALQTGDKLTTFAEIKAQNIHLDMPPVEIEHQINDGDTIRIGNLELEVWHTPGHTDSQLAFRLGDVLFSGDNIYRDGCVGAIDAHHGSNINDFIKSLERIRDSDVVWLLPSHGPFFRKDEKMLNATIDRLRGYLKMADFGTLANEWPLMDQWENEVADGTLPDGVGTEKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQ54</accession>
    <name>A0A518IQ54_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_11940</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013784">
        <property type="entry name" value="Carb-bd-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49452">
        <property type="entry name" value="SSF49452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1770" mass="190300" checksum="81B65AA97602FA11" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQ78</accession>
    <name>A0A518IQ78_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glucose--fructose oxidoreductase</fullName>
            <ecNumber evidence="2">1.1.99.28</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">gfo_2</name>
        <name evidence="2" type="ORF">Mal33_11830</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.99.28" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047061">
        <property type="term" value="F:glucose-fructose oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
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        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
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        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02894">
        <property type="entry name" value="GFO_IDH_MocA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKS_ER" evidence="1">
        <location>
            <begin position="52"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="745" mass="79796" checksum="6C4D97DC4BC50A68" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQA2</accession>
    <name>A0A518IQA2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Inner membrane protein YrbG</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">yrbG_1</name>
        <name evidence="7" type="ORF">Mal33_12450</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1420.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004481">
        <property type="entry name" value="K/Na/Ca-exchanger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004837">
        <property type="entry name" value="NaCa_Exmemb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044880">
        <property type="entry name" value="NCX_ion-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10846">
        <property type="entry name" value="PTHR10846"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01699">
        <property type="entry name" value="Na_Ca_ex"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00367">
        <property type="entry name" value="TIGR00367"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="33"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="66"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="98"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="125"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="163"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="204"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
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            <begin position="234"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="269"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="298"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="328"/>
            <end position="347"/>
        </location>
    </feature>
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        <location>
            <begin position="4"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="Na_Ca_ex" evidence="6">
        <location>
            <begin position="171"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV55275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="359" mass="37456" checksum="213E4ADA01EE2210" modified="2019-10-16" version="1">MDYLFLLLGLAVLVVGAELLVRGAVTLAEVARISPLVIGLTVVAFGTSAPELAVSTISSLHGDSAIALGNVVGSNILNVLLILGVSAVIVPLSVSSQLIRLDVPIMIGVSVFIWLAAVDGAIGRGEAVCMLLTFTCYTVWLIRAGRKESDGNADDSNQAPKPSLIRLSLNIAILLAGLALLVWGAKMLVDSATSIARSLGVNDIVIGLTIVAAGTSLPELATSVVAAIKGQRDIAVGNIVGSNVFNLLMVLATASVVSKSGISVAPEVLWFDVVVMVLTAILCLPIFVSHAAVSRVEGVVMLLLYATYTFLLLAASQQFSWASNVKSAFAFGFFPLVCIVVSCLAWRDRNNTKDHTGSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQF1</accession>
    <name>A0A518IQF1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">dTDP-6-deoxy-L-talose 4-dehydrogenase (NAD(P)(+))</fullName>
            <ecNumber evidence="2">1.1.1.344</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">tal_1</name>
        <name evidence="2" type="ORF">Mal33_12600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.1.344" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
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        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="5"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="341" mass="37937" checksum="E98AAE63B96D30A7" modified="2019-10-16" version="1">MNESVLVTGAAGFIGSHLVADLVKQGRPVRCLVRKTSNRKWLDGLDVEMVEADLSDEAQVSKALENVGAVYHLAGAVAGTRQQLQHANVTCTRGLLQGCAKMPNPVRVVHVSSLAAAGPSTRQRPRRATDPCQPVSQYGHSKLAGEQVALEFADRLPITIVRPGAVFGPRDSEFARLFRLIRSLRCNVLLGLHDPPVGMVHVADLVKLLVEAEMQGTCLQSLAGPMHSYSVEDGVYFGSDPNPLSFRELGLRVRGMLQRPHAWTIPLPVTAVRPIALMSQVVAQVKQQRITFNLDKLREGAQDAWTCEVKREFAELNWRPRRSIDERFRETIQWYFDNHWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQV8</accession>
    <name>A0A518IQV8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">von Willebrand factor type A domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_14160</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13519">
        <property type="entry name" value="VWA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="55"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="3">
        <location>
            <begin position="94"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="377"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="692"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="887"/>
            <end position="909"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="942"/>
            <end position="1049"/>
        </location>
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        </location>
    </feature>
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        </location>
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        </location>
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    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
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            <end position="1022"/>
        </location>
    </feature>
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        <location>
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            <end position="1147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
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            <end position="1193"/>
        </location>
    </feature>
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        <location>
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            <end position="1245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1246"/>
            <end position="1271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV55443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1271" mass="138497" checksum="45AE860A3571B8B2" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IR00</accession>
    <name>A0A518IR00_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_14760</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
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            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="279" mass="31909" checksum="943BBF3BDE322B32" modified="2019-10-16" version="1">MKVSGFTIARNAIHYDYPVVESITSVLPLVDEMIVAVGESCDGTRALIQSIDSPKIRIIDTVWDETSRQNGTVLADQTNLALQHCTGDWCFYIQADEVIHEADLDRIGSCMRRHLKNPRIEGLSFRYHHFRADYNIRDPLPYRRQVRIVRAGVGVQSVGDACGFAVENRKLAAASTGAWVYHYGYVKPPKTMAAKTDYFTSLYDGRQVAPGEQAEAEAYAWNLKTCEPFRGSHPRVMEARIAAKDWETPEFRMCSRWYNPNFWSGLLYKNTRTFRRWVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IR72</accession>
    <name>A0A518IR72_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Mal33_15740</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031768">
        <property type="entry name" value="CBM60_xylan-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011429">
        <property type="entry name" value="Cyt_c_Planctomycete-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011478">
        <property type="entry name" value="DUF1585"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013036">
        <property type="entry name" value="DUF1587"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013039">
        <property type="entry name" value="DUF1588"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013042">
        <property type="entry name" value="DUF1592"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013043">
        <property type="entry name" value="DUF1595"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16841">
        <property type="entry name" value="CBM60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07635">
        <property type="entry name" value="PSCyt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07627">
        <property type="entry name" value="PSCyt3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07624">
        <property type="entry name" value="PSD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07626">
        <property type="entry name" value="PSD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07631">
        <property type="entry name" value="PSD4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07637">
        <property type="entry name" value="PSD5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
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        <location>
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            <end position="769"/>
        </location>
    </feature>
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        </location>
    </feature>
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        <location>
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            <end position="189"/>
        </location>
    </feature>
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        <location>
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            <end position="327"/>
        </location>
    </feature>
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        </location>
    </feature>
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            <end position="561"/>
        </location>
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        <location>
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        </location>
    </feature>
    <feature type="domain" description="PSD2" evidence="2">
        <location>
            <begin position="689"/>
            <end position="762"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF16841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV55597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="769" mass="85671" checksum="015ED1E99E1BA679" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IR89</accession>
    <name>A0A518IR89_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3 4">Single-stranded DNA-binding protein</fullName>
            <shortName evidence="2">SSB</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ssb</name>
        <name evidence="6" type="ORF">Mal33_15830</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Homotetramer.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04496">
        <property type="entry name" value="SSB_OBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00984">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000424">
        <property type="entry name" value="Primosome_PriB/ssb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011344">
        <property type="entry name" value="ssDNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10302">
        <property type="entry name" value="PTHR10302"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00436">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002070">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00621">
        <property type="entry name" value="ssb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50935">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="103"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="123"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR002070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV55606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="155" mass="16867" checksum="174ABEC1E614AA35" modified="2019-10-16" version="1">MASYNRVILLGNMTRDVELRYTQGGTAVTDIGLAVNDRRKSQTGEWVDETTFVDVTLWGRTAEVASEYLSKGSPVLVEGRLKLDTWETEGQKRSKLRVVCDRMQMLGSGGGSHREVGGDDNSLQEPSHHSAPPSNPAASPSGSRGDDFSDPNIPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRF3</accession>
    <name>A0A518IRF3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GDSL-like Lipase/Acylhydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_16490</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SGNH_hydro" evidence="1">
        <location>
            <begin position="189"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="380" mass="41831" checksum="02FA2FD46F9048C3" modified="2019-10-16" version="1">MKIKLLPIVILLVCNPFRPGETSAEETSTWKYTPAALQPFWVGDRIEGESVLFVRDAKTGEARGSLLFPIAEIESVKSSSGEITFREGTDYRFKPGTREIVVPAGSQIVTTLPEELRRPAKSQRHQLTHRDGNGEILFGATLEYHQMQTLVTYKTAEKNWPVAAPKFDPAALPTTIGKLRDKKPLSIVLLGDSISTGCNASGWGGGAPFQPAYQDLLLQHLKTQYSPNITLTNLSIGGKATPWGVSMIDEVASHKPDLVIIAFGMNDSAGISAENYGKYTAEMIAKTRAQLPEAEFILIATMLGNRDWIRLNHDVFPQYRDTLASLCEPGVALADMTSVWEEFFQRKQDADLTGNGVNHPNDFGHRVYAQVLSALLVDSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRP7</accession>
    <name>A0A518IRP7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tetratricopeptide repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_17330</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="199"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="300"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="43"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="43"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="464" mass="51193" checksum="1338342BFA8F6EF7" modified="2019-10-16" version="1">MDRRNRQPACPTPLTAPRFSGLSLVLVLVAIASAVLMGCSPGPTAATNPQRPESSSGSSQPSVSQTQQTDDDVSKETVEVSQRTRIESQSPIDSMREGKQYRAALNAIDSGNLDFAKSQQRQLKDHPTYAVLSDAIEAAILANRGDYDAAMQIAEQISRVPIMQSESYMIAADVFRGQGRWGDAIGCLQQAITINPGLARAHRWLGILHYDLGAMRQATQHLRIAADADPTDFGVLRLSARIHGEYQNYPEAIVDAKMALQRNPPPPIETELRLRLSDSLRQLRKCDEAIEAIADCPESAEVWACRAQCWETAGDSDRAVDACKRALQVDPDNRIANLVYGRVLAAQREPETAIQHLERALAQEPSDHEAMFLLGRALIMAKRGEEGKTLIERSTQIKERFLKIADLHLQALENPQDVQVRIELAELTLESEKPQIAAMWYRAVLGIEPNNPTATHALKTLSDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRX3</accession>
    <name>A0A518IRX3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Putative fluoride ion transporter CrcB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9 10" type="primary">crcB</name>
        <name evidence="10" type="ORF">Mal33_18260</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 9">Important for reducing fluoride concentration in the cell, thus reducing its toxicity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the CrcB (TC 9.B.71) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903425">
        <property type="term" value="F:fluoride transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00454">
        <property type="entry name" value="CrcB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003691">
        <property type="entry name" value="CrcB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28259">
        <property type="entry name" value="PTHR28259"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02537">
        <property type="entry name" value="CRCB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="37"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="71"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="103"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV55847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="126" mass="12451" checksum="2B5357131030231D" modified="2019-10-16" version="1">MFADVLAVAAGGAIGSALRFLVTLAAATALGLGAAGTIAVNVLGCLLIGGLAEATILGTSMPDRLQLAIRVGLLGGLTTFSTFGYEAVVFAEKDGFGPAAAYVTTNLVLGIGAVCLGIFGIRALYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IS00</accession>
    <name>A0A518IS00_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative monovalent cation/H+ antiporter subunit B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Mal33_18390</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025383">
        <property type="entry name" value="MbhD-like_TM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13244">
        <property type="entry name" value="DUF4040"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="51"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="86"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="151"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4040" evidence="8">
        <location>
            <begin position="10"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV55860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="183" mass="19605" checksum="0212EFED5EDE6FE9" modified="2019-10-16" version="1">MNLIVFTILAMLAATAVTVARIRDLWAAIMFTGIYSFLSASWMLILDAPDVAFTEAAVGAGISTVLMLSTLVLVGPSDAGRRKPALVPLTVVTITGCALVYGTLDMPHFGDPNDPIHLHPRPSFVEKSQVDMHGLPNVITSVLASYRGYDTLGETTVVLTAGIAVLLILRKEKDEPEREAVSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISA6</accession>
    <name>A0A518ISA6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sodium/pantothenate symporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">panF_2</name>
        <name evidence="8" type="ORF">Mal33_19430</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015204">
        <property type="term" value="F:urea transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1730.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031155">
        <property type="entry name" value="DUR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038377">
        <property type="entry name" value="Na/Glc_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001734">
        <property type="entry name" value="Na/solute_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018212">
        <property type="entry name" value="Na/solute_symporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46154">
        <property type="entry name" value="PTHR46154"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00474">
        <property type="entry name" value="SSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00456">
        <property type="entry name" value="NA_SOLUT_SYMP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50283">
        <property type="entry name" value="NA_SOLUT_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="16"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="78"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="127"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="165"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="194"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="232"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="272"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="306"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="368"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="394"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="422"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="447"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV55964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="494" mass="51935" checksum="140E8D5B552FD260" modified="2019-10-16" version="1">MIDGLIAANTILSPNAGYALLFAFGVLWVGLGVWWGRQAKSYDGFAVAGRNVGLALGTATAVATWITSNTTMLAPQFALQLGIWGALTYSTASFGLFAFAPMSGRIRQLMPHGYTAVEFVHRRYGQLGAIPFLIISLFYAMTWLISMAMAGGKLLNVLSGIPYEVGMTVVLGVCVLYTLFGGMYAVIGTDFIQSLIILVGLVVVAIAVLLHVDISDVHSKLQTERPMLLSVMFPAALMAVFNNMLFGFGEIFHSNVWWSRAFAMRDGVGPKAYALGGLLWLPVPIVAGFLGLAAPALGIGISQPDIAGPLVAATLLGTGGALFVFVIVFCSLASSIDSLLAATSDLMVNDIFERAAGKTMPDATKRKLSVLSILILGLIAWSVAWANIGTLATVLFFAGPMVGSCIWPIVGGLYFSRPSPVAAGAAMVAGSSLGLVAYFTIGWFVASLVGATVSGIVFGLITWIVPDSFEFDQLSRQEPGPADGSPTTTEGCVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISE0</accession>
    <name>A0A518ISE0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="11 12">Na(+)-translocating NADH-quinone reductase subunit C</fullName>
            <shortName evidence="11 12">Na(+)-NQR subunit C</shortName>
            <shortName evidence="11 12">Na(+)-translocating NQR subunit C</shortName>
            <ecNumber evidence="11 12">7.2.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11 12">NQR complex subunit C</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11 12">NQR-1 subunit C</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11 15" type="primary">nqrC</name>
        <name evidence="15" type="ORF">Mal33_19690</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11 12">
            <text>a ubiquinone + H(+) + n Na(+)(in) + NADH = a ubiquinol + n Na(+)(out) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:47748"/>
            <dbReference type="Rhea" id="RHEA-COMP:9565"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="7.2.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11 12">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="11 12">Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cell membrane</location>
            <topology evidence="11">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11 12">Belongs to the NqrC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="7.2.1.1" evidence="11 12"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016655">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006814">
        <property type="term" value="P:sodium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00427">
        <property type="entry name" value="NqrC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007329">
        <property type="entry name" value="FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010204">
        <property type="entry name" value="NqrC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37838">
        <property type="entry name" value="PTHR37838"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04205">
        <property type="entry name" value="FMN_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF009437">
        <property type="entry name" value="NQR-1_subunit_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00900">
        <property type="entry name" value="FMN_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01938">
        <property type="entry name" value="nqrC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="1 11" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11 12" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="11 12" id="KW-0288">FMN</keyword>
    <keyword evidence="8 11 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 11 12" id="KW-0520">NAD</keyword>
    <keyword evidence="15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0732">Signal</keyword>
    <keyword evidence="7 11 12" id="KW-0915">Sodium</keyword>
    <keyword evidence="10 11 12" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="4 11" id="KW-1278">Translocase</keyword>
    <keyword evidence="3 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="11 12" id="KW-0813">Transport</keyword>
    <keyword evidence="11 12" id="KW-0830">Ubiquinone</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021773411" description="Na(+)-translocating NADH-quinone reductase subunit C" evidence="13">
        <location>
            <begin position="29"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="domain" description="FMN_bind" evidence="14">
        <location>
            <begin position="155"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="modified residue" description="FMN phosphoryl threonine" evidence="11">
        <location>
            <position position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="QDV55990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="273" mass="29673" checksum="205B764A5730D99E" modified="2019-10-16" version="1" precursor="true">MPPRDSMTNTVLVALVLCLVCSSLVSVAAVKLKPLQEINKALDVQKNILDATGMAMEQLGIPANQLTKTQVETLFEQIETKLVDLETGDYVEASPEEVKSFDPRKAARDKDESTAIGDTAYPIGLGRRETVSKVYLVKTADGQLSQVVLPVYGNGLWSTLYGFLALDKNLETVKGITFYEHGETPGLGGEVDNPAWKAEWEGLTIYNDEGQPELGVSKGPAPLDDNYLVDGLSGATITCRGVTNLVRYWVSEDGFKPYLEKLKTELPKSGGKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISK2</accession>
    <name>A0A518ISK2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_20440</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="380" mass="41665" checksum="2694573BE3710088" modified="2019-10-16" version="1">MLVRTQITAERQRRGFTIVELLVAMALIGVMASMVGMALSSAQGDARRARAKLQVAKIREILLHRWDDYMVMQMPVSIGGTKQRQASRERARVRLALLRDRMRIEMPDRITDLASPAQTWVTAVRTAPGTYAAATADSVTVPLFDIYRERVVQTYVALGKLPASATYADVFPGGVDSLPPSSSDNDLWTREHQSAECLYLILSAMNFAGRPALDAFRPSEIADTDGDSMPEIVDPWGTPIAWARWPAGYWVGISETDPVTDFGPDGFDLLNGSLRYRDTSFPDPFNLQPLVVSAGPDGEFDTRFLNGTDPNSTVEISYVGAQFRIVFGGLNEIDPYYVNTDLADADNDYTKGGFEGVGSRADLDGDGYDAAVDNIISSEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISK8</accession>
    <name>A0A518ISK8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_20120</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022163005" evidence="1">
        <location>
            <begin position="23"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="272" mass="29361" checksum="B5EDEF7DBD989801" modified="2019-10-16" version="1" precursor="true">MKLASIAFLMIFAAAVAPGASADDTTPATKPASTFPNQVDCEGTYPHHLQGVCTDGDAIYWSFTTTLVKTDLDGKVITKIPVANHHGDLCIDQGKIYVAVNLGRFNDPEGNADSWVYVYDATNLKEIARHETQQVFHGAGGIGVYDGNFYVVGGLPSDIEVNYVYQYDADFTFVKKHIVTSGQTLLGIQTATFAHDRWWFGCYGSPAETLVTDANFKMIGRYKFNCSLGIEKLPGGELLVASGRCSKGTGCTGRVTRAVPDAANGLKLLQTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISM6</accession>
    <name>A0A518ISM6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Peptidase family M50</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_20730</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="160"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="218"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="257"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="289"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="377"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="424"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="domain" description="HlyD_D23" evidence="3">
        <location>
            <begin position="450"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="492"/>
            <end position="519"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV56094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="708" mass="78029" checksum="FA9E1CB1D7AA1D01" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISN0</accession>
    <name>A0A518ISN0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_20680</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="86" mass="9082" checksum="62C3C1FF860497A7" modified="2019-10-16" version="1">MATPDASQGIEKGGEPSLAEVRPRCALDDGESLLEELGAEELGVEELGVEELGVEELGVEELGVEELGVEELGVEELGAFPRRLCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISS9</accession>
    <name>A0A518ISS9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_21240</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="234" mass="25888" checksum="F9B0F4D4FA0672CB" modified="2019-10-16" version="1">MASILAGLLHQPLLSAVTRCYRSSDAIDESSITHLYLLDGDRLLETAIAMASDGKPILIPQEATLRSVQCGAAPSPDEVKPQLLLELGAAPGQTELVPGAAWDDYQRIEYLGQWMDQNPDAVVCMLAEALASGRLRRIVDRKFTDQAASRLKIKPLDPIDHSADRWWRSTTGCKEFYGQSIAWLYDWISPNGTPRPDDMSPQEYEDAFRQRLRSLGVRLSDAPPQPELSPQGAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITB2</accession>
    <name>A0A518ITB2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HGSNAT_cat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_23140</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012429">
        <property type="entry name" value="HGSNAT_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07786">
        <property type="entry name" value="HGSNAT_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="163"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="204"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="237"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="330"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="356"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="389"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="domain" description="HGSNAT_cat" evidence="2">
        <location>
            <begin position="17"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="423" mass="46359" checksum="AAB3CF4EA7ED05E4" modified="2019-10-16" version="1">MSSAAVDPVATGARSTRVVSMDQFRGYAVAGMFVVNFLGGLSVTHQVLKHNNTHFSWADSIMPGFLFACGFSYRLSVIKKGAKAGRRATWIGMLRRSLGLVLLSLVLYGLGGSFKTWADVDSAAVHKFIAELIKADLWEVLAIIGVTQLLLLPVIECSPRVRLAIAIGLSIAHITLSGWFNYWFVYGQPNGFDEWMGTTGRRAWDGGCFGLISWSVVMLAGSLVYDLMSTQSIRRAVGVLLVSGTVLMGLGYAASCLTTLYDVRETNAVPVVSDKDERFAASPVVPPWANLEGRSWGSLLAEAPFMEPPGTEQRKLNYWMMDKRVVTQSFIWFSIGMTCVVYAMFVLACDLGSLRVGLFTLFGQNALIAYVIHHPVAEMVLQVVPKDSPLWWATAGLLIYFLITWLLVSAFAKAFTPARPAKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITH1</accession>
    <name>A0A518ITH1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Alpha/beta hydrolase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_23780</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="275" mass="30075" checksum="43C69609D4100B1F" modified="2019-10-16" version="1">MWLRKRLADRFILRPSRHVVDDPQPATRLIVDGPQGDIECFATRKPAGTQVAAPLDVDQPPADLLILKLPGTGGRAERSTAFPALLFQPRDVEVWTWNPPGYGLSQGSASLRHIPAAVLAVWDHLHQHRVGPNTKTLIVGNSLGSVTALYLASQRAADALMIRNPPPLVDMVRDGNAWWNAHRGGTWIAASIEAKMDATTTASHCQLPALFVQSQLDALVPARLQQSIIDAYAGPHRLVVLPEAQHDTPYRADDLDAIQAGLQWLMPEMFGMAPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITJ5</accession>
    <name>A0A518ITJ5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_23970</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="77" mass="9121" checksum="6E1D2AF89BDBD674" modified="2019-10-16" version="1">MKAYQVRICAILNALDGCRWALTADDLCFMLRMENHEYDQSTIRADLHFLKEIDTVTAEDAVRQDGRTVKKWRRKKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITJ7</accession>
    <name>A0A518ITJ7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NACHT domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_24010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="1">
        <location>
            <begin position="260"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1634" mass="181583" checksum="3BA99B6DCD23CFA9" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITS5</accession>
    <name>A0A518ITS5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_24850</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="46" mass="5175" checksum="36E9B429CA3ADA7E" modified="2019-10-16" version="1">MRQADRQKFADLLTLLVGKTLVKATFLAPHSPKLKHSMGGRFTYSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITU6</accession>
    <name>A0A518ITU6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phage head-tail joining protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_25030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008767">
        <property type="entry name" value="Phage_SPP1_head-tail_adaptor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038666">
        <property type="entry name" value="SSP1_head-tail_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05521">
        <property type="entry name" value="Phage_H_T_join"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01563">
        <property type="entry name" value="gp16_SPP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="115" mass="12968" checksum="8A593E25142E1057" modified="2019-10-16" version="1">MKSKRRIGRLRHRVTIKRRSIEYDEVGQVIETYTDIKTVAAAIETFGGKNLAQQGVADASLIVTIRHLAGLTPYDLLACRGEILYIGAIIDPEPDHPGRWLEVYCSKEPFENVED</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IU68</accession>
    <name>A0A518IU68_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator MprA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">mprA_2</name>
        <name evidence="3" type="ORF">Mal33_26140</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="4"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="130" mass="13650" checksum="87B33A8C348E7C8E" modified="2019-10-16" version="1">MPGTILLVDDNHEILTGVRMRLGAVGYQTRTACDGQTGIQSAIQHPPDAIVMDVRMPGIDGLQAVAELQCRPDTKDIPIIVLSASLADEESALDAGAHFFVKKPYVGTELIAAIRAAVGLKSVPSKGGSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUD1</accession>
    <name>A0A518IUD1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_26910</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021883811" evidence="2">
        <location>
            <begin position="23"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="162"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="183" mass="19165" checksum="0CC3E26318FE1C95" modified="2019-10-16" version="1" precursor="true">MFRFARTSLLITIAAITGCSKAASDPGPSFIPVSGTLTLDGQPLPFKSVRLSPTGGTEGRGAAGYSDPEGRFHLVAVVSDKLNDIAGCPPGHYRVIVNEPMIPISEADFETGNQTSAAPTAEPAVAILLPDPNAKSDIPAVYRSDNTSPLEVEIREENTTLTVELQSKPSPSPSPADAVQHDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUL2</accession>
    <name>A0A518IUL2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Outer membrane protein OprM</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">oprM_1</name>
        <name evidence="3" type="ORF">Mal33_27660</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010131">
        <property type="entry name" value="RND_efflux_OM_lipoprot_NodT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01845">
        <property type="entry name" value="outer_NodT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0564">Palmitate</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1134">Transmembrane beta strand</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="537" mass="59012" checksum="D5FBCEBB1CE3B6A5" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUQ0</accession>
    <name>A0A518IUQ0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tetratricopeptide repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_28140</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="42"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="71"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="113"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="160"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="356"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="412" mass="45098" checksum="C08D1C06B1A3817A" modified="2019-10-16" version="1">MMSPVQPVARMLVPHAVALLAVASSVGLLLQWRTPAGDAILVFGRVDVLVCSLFLSLPFALELLRRGRSALLGISAAAMFCGWGIVVALMVWAASALPRGEFSEWSLVAIRGAIGLCVASGSVGFANLVAHLAGGRRDRDPSMSPDGDIERVLSAWPRRAIFAGLWILVPAVYAHAVAADLQKALTESLQNQRIALAARQADQLSQLAPAQTIDGTPLVALLPQLQQRRTQLIDQLATATEPTSLGEIAQQITTLVQLERHDEALRRIEPLTRGANFHPVALDYQGLCFQRMERPEESMAAYRRSLEFWMSQPDGDAKRSGLVSGYKGVGFAARRLQMRLLEEQAYQQLVEIAPTGEHHFLLAQCYREHQKTQLAAEHFKAAMQQDPSMQSQIEAILATLSMDHFSCLSVPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IV17</accession>
    <name>A0A518IV17_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_29330</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022068106" evidence="1">
        <location>
            <begin position="25"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="184" mass="19898" checksum="D45AD328302CB490" modified="2019-10-16" version="1" precursor="true">MNAKLSIRTTLFAAVAAIAVPASAGWLDVLVSPVAYEEIAVPEAINAPVQEDHSVMIETAPPVMESTYESYAPIYSPAPAAYSRGGHCCEQPRVIYRNHPILAMLMHKCKAGQAGQVVVQVPTGCCPTEVALCVPLCCTTCPPEVSKSRDLLGRCVFQYCWPCGTKINIVQRYTGDLVVHSYEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IV79</accession>
    <name>A0A518IV79_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_29760</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010869">
        <property type="entry name" value="DUF1501"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07394">
        <property type="entry name" value="DUF1501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022078213" evidence="1">
        <location>
            <begin position="34"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="464" mass="51021" checksum="BC41DE21ABAB9F70" modified="2019-10-16" version="1" precursor="true">MKNVTSRRQMLSASACGFGSLALADLMTRQAQAATPSSSLAQPATHHLPRARRVIFLFMHGGPSHVDTFDYKPRLQADDGKDLPYDLPTAAIDAKLKLLGSPWKFKQHGQSGLWCSELMPHTARHLDEMCIIKSLHSRGQSHGQAVSMLNTGSDNLVRPSVGSWLSYGLGTENEDLPSFVALAPSTGHGGPRNYGTAFLPAIHQATAIGSNGKLGDAQVKYLNRGDLPPAEQNRQMDLLQTLNRRHLDRAGQDQQIEGAIEAYELAFRMQQAAPQVLSLDEEPQHILDLYGVGQEPTDNFGRSCLLARRLAEAGVRFIQVSTGNVWDQHSNLKSGHEKNSLKTDQPVAGLIQDLKQRGMLEDTLIVWGGEFGRTPVVQGANGRDHNPQGFTMWMAGGGVKGGTSYGETDEFGYYSQQDRVHMHDLHATILHLMGLDHQRLTYRYAGRDFRLTDVAGRVVTELFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVN4</accession>
    <name>A0A518IVN4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">LPS-assembly protein LptD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">lptD</name>
        <name evidence="2" type="ORF">Mal33_31410</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="187"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="203"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1127" mass="124197" checksum="972CCA6866D56358" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVQ9</accession>
    <name>A0A518IVQ9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_31770</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="67" mass="7016" checksum="5B74684C2E9987C6" modified="2019-10-16" version="1">MVIAGFLFILAILGLELAMGVAVFGFTGGKAVVVRADDPGKFWFSIVLQLIFGLALPAALCFGSLQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVT9</accession>
    <name>A0A518IVT9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">50S ribosomal protein L36</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ykgO</name>
        <name evidence="4" type="synonym">rpmJ</name>
        <name evidence="6" type="ORF">Mal33_31990</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the bacterial ribosomal protein bL36 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00251">
        <property type="entry name" value="Ribosomal_L36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000473">
        <property type="entry name" value="Ribosomal_L36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035977">
        <property type="entry name" value="Ribosomal_L36_sp"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00444">
        <property type="entry name" value="Ribosomal_L36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57840">
        <property type="entry name" value="SSF57840"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01022">
        <property type="entry name" value="rpmJ_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00828">
        <property type="entry name" value="RIBOSOMAL_L36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV57197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="50" mass="5711" checksum="6E516C3C86DE18F1" modified="2019-10-16" version="1">MKVVSSIGTLKNRHPDCQVVKRRGRIYVICKSNPKFKVRQGGAKSKKARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVU5</accession>
    <name>A0A518IVU5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_32150</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="110" mass="12787" checksum="3405C13196D16D61" modified="2019-10-16" version="1">MMSEGQLEQLSLDGFHETGWEYANGVDISPNGDDPERDDYRVVVLKDRVAVADAWANQDRLQLGARCRHAGWRDSGVMIWKRRDDMPQKTSAPPRFKHLQWRAYQTTREV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVW2</accession>
    <name>A0A518IVW2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_32350</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039448">
        <property type="entry name" value="Beta_helix"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006626">
        <property type="entry name" value="PbH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13229">
        <property type="entry name" value="Beta_helix"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00710">
        <property type="entry name" value="PbH1"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021766487" evidence="1">
        <location>
            <begin position="39"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="domain" description="Beta_helix" evidence="2">
        <location>
            <begin position="132"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="Beta_helix" evidence="2">
        <location>
            <begin position="288"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="453" mass="48279" checksum="C36E75D5DB2ECEA4" modified="2019-10-16" version="1" precursor="true">MISTPAFPSLLSFRSAPFSAALRVAILALLCLPSFSAAQDNPADKLISEGRLLLPAGTLEIDQPLEIDLSKTGPLHIVGQGHSRIVMNGAGPAIRITGTLKGTAAPKTIKPQVFEKENAPLIAGFEIIGNHPEADGIELVGVMQPTIRDLTIRKSRHAIRLTSRNRNLIVSDCHLYENSGAGVYFDHVSLHQANIVGSHISYNAAGGVVIRGGDVRNVHISGCDIEANMGAPDAPPAANVLLDSEEGSIGEVAITGCTIQHTHHGKDSANIWIDLQSNRQKFTEELRHGNVTISGNILSDVQHNIYVQNTRGVAITGNTIWKGFDRNILLKNCEAVVVSGNTFDRNPRYGYGDASDAKLGIRLSQCSGCLLVANAINGVGDVDGAIELHRCSQIVVSQSTIRGFPKAGVLLDECVQSIVNNCIVTEENAAAEAIRQLGGEGNRIVENMVIETP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IW16</accession>
    <name>A0A518IW16_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6 9">50S ribosomal protein L22</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6 10" type="primary">rplV</name>
        <name evidence="10" type="ORF">Mal33_32860</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.</text>
    </comment>
    <comment type="function">
        <text evidence="5">This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.</text>
    </comment>
    <comment type="function">
        <text evidence="6 9">This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6 8">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the universal ribosomal protein uL22 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00336">
        <property type="entry name" value="Ribosomal_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01331_B">
        <property type="entry name" value="Ribosomal_L22_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001063">
        <property type="entry name" value="Ribosomal_L22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036394">
        <property type="entry name" value="Ribosomal_L22/L17_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005727">
        <property type="entry name" value="Ribosomal_L22_bac/chlpt-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13501">
        <property type="entry name" value="PTHR13501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00237">
        <property type="entry name" value="Ribosomal_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54843">
        <property type="entry name" value="SSF54843"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01044">
        <property type="entry name" value="rplV_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 6 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="6 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6 8" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV57282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="118" mass="13316" checksum="96AF71C9852DBE31" modified="2019-10-16" version="1">MSFNASHRYCRMSAQKVRLVADLIRGKYADEALDILKYQPQRGARMLEKVLRSAIGNAQDPDQNGGRNIGVEELVVNDVRVDGGPMFKRIRPRARGTAFMIKKRMSHIHVGVVPLDEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IW39</accession>
    <name>A0A518IW39_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">N-carbamoyl-D-amino acid hydrolase</fullName>
            <ecNumber evidence="2">3.5.1.77</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_33030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.5.1.77" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047417">
        <property type="term" value="F:N-carbamoyl-D-amino acid hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="SSF56317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CN hydrolase" evidence="1">
        <location>
            <begin position="6"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="289" mass="32360" checksum="040031F0A1019F04" modified="2019-10-16" version="1">MANSVVKLSLVQMSCTDSKAENVERAVSQIRQAAADGGQVICLQELFNGPYPCQTEDHCQFDWAETIPGPTTERMSQLAAELGVVIVVSLFEKRTAGVYHNTAVVLDADGSTAGVYRKMHIPDDPLYYEKFYFTPGDLGFKVIETRFAKLGVAVCWDQWFPEAARLMALAGAEILLYPTAIGWIDEEKEEYGTTQYESWQTMMRSHAIANGLWLGAPNRVGVEGRLQFWGGSFIANPNGKVITQGSHEEPEIITADCDLNMIDVVRTHWPFLRDRRIDAYQGLMRRVID</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IW86</accession>
    <name>A0A518IW86_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_33630</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="63" mass="7434" checksum="B4F5399C36213B65" modified="2019-10-16" version="1">MLPMTPVYMLYFIPLLISISFVYAGTRHEDPKQILVQAWHTAYWILAFMGLIFALLWVVGWFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWH4</accession>
    <name>A0A518IWH4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Fumarate reductase flavoprotein subunit</fullName>
            <ecNumber evidence="11">1.3.5.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">frdA</name>
        <name evidence="11" type="ORF">Mal33_34540</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.3.5.4" evidence="11"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102040">
        <property type="term" value="F:fumarate reductase (menaquinone)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008152">
        <property type="term" value="P:metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.700.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003953">
        <property type="entry name" value="FAD-binding_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003952">
        <property type="entry name" value="FRD_SDH_FAD_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037099">
        <property type="entry name" value="Fum_R/Succ_DH_flav-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015939">
        <property type="entry name" value="Fum_Rdtase/Succ_DH_flav-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030664">
        <property type="entry name" value="SdhA/FrdA/AprA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011280">
        <property type="entry name" value="Succ_DH/Fum_Rdt_flav_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027477">
        <property type="entry name" value="Succ_DH/fumarate_Rdtase_cat_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11632">
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        <source>
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    <sequence length="657" mass="72604" checksum="0866B203EF3EDBBD" modified="2019-10-16" version="1"> </sequence>
</entry>
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            <authorList>
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                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
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    </evidence>
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    <sequence length="174" mass="20331" checksum="A2B705E381B288D3" modified="2019-10-16" version="1">MEHSQSSATTVHIRWMIRRDMPSVLDIEAASFEFPWSEDEFIRCLRQRNCIGMVAEEDDQVVGFMIYELHKNRLHILNFAVNPEVRHRGVGQAMIGKLVGKLSHDRRNRIMLEVRETNLDAQLFFRNSGFKAVSVLRDFYDDTCEDAYVMQYRYQPSQQEMSVPKGNRIGRMAG</sequence>
</entry>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">Mal33</strain>
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            <end position="25"/>
        </location>
    </feature>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="QDV57673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="66" mass="7212" checksum="75CB70FE9398AADE" modified="2019-10-16" version="1">MSESQESHASQLDKEPSQTKTPVEGATDEPNWIVKTAGAFRGDPVFAEVVKLGKEIRNAEQPELDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXP6</accession>
    <name>A0A518IXP6_9BACT</name>
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        <recommendedName>
            <fullName evidence="2">Isoprenyl transferase</fullName>
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        </recommendedName>
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        <lineage>
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    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
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                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
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                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="2">Binds 2 magnesium ions per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPP synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.-" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004659">
        <property type="term" value="F:prenyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00475">
        <property type="entry name" value="Cis_IPPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01139">
        <property type="entry name" value="ISPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001441">
        <property type="entry name" value="UPP_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018520">
        <property type="entry name" value="UPP_synth-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036424">
        <property type="entry name" value="UPP_synth-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10291">
        <property type="entry name" value="PTHR10291"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01255">
        <property type="entry name" value="Prenyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64005">
        <property type="entry name" value="SSF64005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00055">
        <property type="entry name" value="uppS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01066">
        <property type="entry name" value="UPP_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2 4" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="30"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="74"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="203"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="29"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="77"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="29"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="46"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="78"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="216"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV57860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="252" mass="28493" checksum="073FC8D3BAB4ED9F" modified="2019-10-16" version="1">MSQAEPSSTPDADAETGSSLPRHVAIIMDGNGRWAQRRGLPRIEGHRHGVDTVRRTTEKCAALGIEALTLYCFSSENWKRPPVELDFLMHLLEQYLVEERRTLIDNGLRLKMIGRRDRLPAGVLRELEITQQLCAEHTGMQLVLAVDYGGRAEIVEAVRQLAAKAQQGELQPDAIDEAMVSEHLYTAGLPDPDLLIRTGGDMRISNYLLWQISYAELWVTDRSWPDFREEDLMQALHDFSGRQRRFGGLLSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXU4</accession>
    <name>A0A518IXU4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_39210</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="392" mass="44062" checksum="9DBDA2A02F2B7FEC" modified="2019-10-16" version="1">MNQREKLLVYLVGGLVVAVGLQFSLSGYRSGLQTRANKLRNLEDKLIDQQEQEFAGLQAETQIAEYRRRSLPSDPQRAQAEYKEWLEKLVSQSGLQNRAVDYVGEQGSNKLYRVYTFRIGGVGNIQKVSEFLTAFHEKNYLQRAKKLVLRPSSEEGKLLMNIDVEAIALADAARDQPAPSTTDPRVDGVAPLLVEAIVNRNMFSPANQPPRYSGEKTLTASIDTDFSKRLKFDDPDKDHRVEYEVVGDLPAGMQFSRGELIGRPKEKGEFDIKVRAWDNGLPSREIETMLVFRVGDPPPEPVVAEGPPPFDESQQAVLTGLVQSRGQWSAWIRVRTQNKLLKLKVGDTFKVGSIEGTIVEVTDRFAVFESDDQRFILRHDRSLADAKADDLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IY62</accession>
    <name>A0A518IY62_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Peptidase C39 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_40430</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005074">
        <property type="entry name" value="Peptidase_C39"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03412">
        <property type="entry name" value="Peptidase_C39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase C39" evidence="1">
        <location>
            <begin position="29"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="228" mass="25100" checksum="A1E8A77D6F7538D6" modified="2019-10-16" version="1">MARLVDLLTMATTTPSAPTTAAKDNALPRSCGPISLVAALRRFGIEQSVDAIWPAVTRKDPFGTRAARSYLLAALARTCQLDAAVLQCQPERAWQAIRTCHDADITVVLNHRAYRAPDEGHFTLLAAIDDATITVDDPFLGKNKQIDRQRFLKLWQPNRETAGHVLIAIDNPTTGQAEEASEDTTTCPRCAAPITLAPNRLFEPTEWNPNGLWQRFFCLGCDASFSPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IY77</accession>
    <name>A0A518IY77_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">HTH-type transcriptional activator Btr</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">btr_2</name>
        <name evidence="5" type="ORF">Mal33_40580</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003313">
        <property type="entry name" value="AraC-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037923">
        <property type="entry name" value="HTH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018062">
        <property type="entry name" value="HTH_AraC-typ_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020449">
        <property type="entry name" value="Tscrpt_reg_HTH_AraC-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02311">
        <property type="entry name" value="AraC_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00032">
        <property type="entry name" value="HTHARAC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51215">
        <property type="entry name" value="SSF51215"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00041">
        <property type="entry name" value="HTH_ARAC_FAMILY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="4">
        <location>
            <begin position="171"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV58041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="275" mass="30571" checksum="6FBFB9F5DB5B8402" modified="2019-10-16" version="1">MASGLKVKHFKVRGSADDGITVHQWESVEHTWPNHSHPEYKLGVSEGGTGTFFYRGQRYFTGPGNLLVIPPNEVHSCTATGAWRYLYAAPNVIASIVRTFDRNGDIEPLLLPPVIDDTQLVELVLQAHRAMDDGDPQLDQESAFYEAICELLVRHASMPDIPKKRGRANIRRVKESLEAKFRENVSLHELAQLAGTSAPYLSRVFSKEVGIPIQAYLSQIRVRRAQQMLMAGESLADVTYAAGFADQSHFTRHFKRFIGVAPGAYSKAVNPSSHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYE7</accession>
    <name>A0A518IYE7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Succinate-semialdehyde dehydrogenase (Acetylating)</fullName>
            <ecNumber evidence="3">1.2.1.76</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">sucD_2</name>
        <name evidence="3" type="ORF">Mal33_41210</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.2.1.76" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008774">
        <property type="term" value="F:acetaldehyde dehydrogenase (acetylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07121">
        <property type="entry name" value="ALDH_EutE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012408">
        <property type="entry name" value="Acetald_propionald_DH-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036410">
        <property type="entry name" value="EutE_PduP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="2">
        <location>
            <begin position="40"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="482" mass="51544" checksum="7B3C8C157152DC33" modified="2019-10-16" version="1">MQYDENLIRSVVSQVLAEVGSPPPIHNGSGGYSGRHGVFHDANEAVAAAQEAFLQLTERTIEERGRIIDHIRRISIDQSEELGTMEMNETKIGRLEHKIAKLLTLGQRAPGIEMIKTEAFSGDKGLAIIERAPFGVIGAITPVTHSLPTITGNAVSMIAGGNTVVVNPHPSGKRVAAEGVRRFNEAIYNDLGIDNLICVIAEPTLETADAIFSHRDVRLICVTGGPAVARAALKSGKRAVVAGPGNPPVVVDETADLDRAARCIIEGGAFDNNLLCIAEKQVFVVEQVFDAMMSAMERAGAARLNSAEIDRLTSQAIAVVGEGEHRHQVAAKDFIGKDAAVLCAAAGKNVAADVELAFGETDYSHPFVGVEQMMPFIPFVRARDVDHAIAMAKESEHGFRHTSMIHSRDVRNMTKMGRAMDTTLYVKNGASMAGLGLGGEGYLSFSIAGPTGEGVTTPQTFTRERRCSIIENLYVVGSPKNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYK9</accession>
    <name>A0A518IYK9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Carbamoyl phosphate synthase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_41920</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003806">
        <property type="entry name" value="ATP-grasp_PylC-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024710">
        <property type="entry name" value="MfnD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040803">
        <property type="entry name" value="MfnD_preATP-grasp"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02655">
        <property type="entry name" value="ATP-grasp_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18301">
        <property type="entry name" value="preATP-grasp_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016766">
        <property type="entry name" value="UCP016766_ATPgrasp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="2">
        <location>
            <begin position="131"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="361" mass="38865" checksum="8533E617815CBD95" modified="2019-10-16" version="1">MQVFIGEYTIGGGLASTPLASLPQGLLAEGTAMHHAICEDTNRCARVVTTIDSRLPHRMDPAIKTIPVDASDELIPQWLAASADCDAAILIAPEFDRLLYKLVAAFRGFGRNVIAPNANFIDATTDKLQLSQRLLSANVPHPISFGPRQAPQESSATEWILKPNDGCGSLEVQRFGSFTQADNQRRRRTGEWIIQAYHPGQAVSIAAIVTAGGIHWLPACLQKMEPPHFSYHGGQSPLPDALADRAERLAAAAFDAVFDRSSRSNDSSSQVGYVGVDLILANDPRDDVVIEINPRLTTSYVGVRHLMKSNLAATMLGLDAAPPILDPSVSAVRWDAAGRADISPGDSASCHRTQTEVSRSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYM0</accession>
    <name>A0A518IYM0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_42020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025350">
        <property type="entry name" value="DUF4254"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14063">
        <property type="entry name" value="DUF4254"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="57"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="204" mass="23507" checksum="9BBDA7E7AD1FFCA6" modified="2019-10-16" version="1">MTLPIDVDAIVQLQAETVAQWHCGPIVNRYSDFMQLVCQQHEHNYRLWHQEDIARAKDVSDAEIAQVKRNIDGLNQKRNDWIEKLDDSITLLLAQQGVETAEDAPINTETSGSAIDRLSIMSLRLYHYEEQLERDDASDAHRELVTQRIALCQQQQADLSNSLKELLVDLFAGRKAHRTYRQMKMYNDPTLNPYLYAAKQLRAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYS4</accession>
    <name>A0A518IYS4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Bifunctional protein FolD</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="8">Methylenetetrahydrofolate dehydrogenase</fullName>
                <ecNumber evidence="8">1.5.1.5</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="8">Methenyltetrahydrofolate cyclohydrolase</fullName>
                <ecNumber evidence="8">3.5.4.9</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="8 11" type="primary">folD</name>
        <name evidence="11" type="ORF">Mal33_42640</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + NADP(+) = 5,10-methenyltetrahydrofolate + NADPH</text>
            <dbReference type="Rhea" id="RHEA:22812"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:57455"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.5.1.5"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>5,10-methenyltetrahydrofolate + H2O = (6S)-10-formyltetrahydrofolate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57454"/>
            <dbReference type="ChEBI" id="CHEBI:57455"/>
            <dbReference type="EC" id="3.5.4.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.5" evidence="8"/>
    <dbReference type="EC" id="3.5.4.9" evidence="8"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00193"/>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004477">
        <property type="term" value="F:methenyltetrahydrofolate cyclohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004488">
        <property type="term" value="F:methylenetetrahydrofolate dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006164">
        <property type="term" value="P:purine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01080">
        <property type="entry name" value="NAD_bind_m-THF_DH_Cyclohyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01576">
        <property type="entry name" value="THF_DHG_CYH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminiacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000672">
        <property type="entry name" value="THF_DH/CycHdrlase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020630">
        <property type="entry name" value="THF_DH/CycHdrlase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020867">
        <property type="entry name" value="THF_DH/CycHdrlase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020631">
        <property type="entry name" value="THF_DH/CycHdrlase_NAD-bd_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00763">
        <property type="entry name" value="THF_DHG_CYH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02882">
        <property type="entry name" value="THF_DHG_CYH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00085">
        <property type="entry name" value="THFDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="SSF53223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00766">
        <property type="entry name" value="THF_DHG_CYH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="3 8 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 8" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="7 8" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="4 8" id="KW-0521">NADP</keyword>
    <keyword evidence="1 8" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="5 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 8" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="THF_DHG_CYH" evidence="9">
        <location>
            <begin position="6"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="THF_DHG_CYH_C" evidence="10">
        <location>
            <begin position="125"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="166"/>
            <end position="168"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="200"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="241"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QDV58246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="294" mass="30811" checksum="80E5410F684A6650" modified="2019-10-16" version="1">MTARILDGKAIAAEIRGETAQQTADWIAKGGKQPCLAAVLVGSDPASEVYVRNKQRACERAGIDSQLHRLDASTSQAELIAVVERLNNDPHVDGILVQLPLPAGLDEREVLDVVAPMKDVDAFSPENVGLLVQGRPRFLPCTPHGVVQLLKRCEIPVPGKHVVVIGRSDIVGKPMALLLAARDGSCGPEAANATVTIAHSQSDDLEGIVRSGDIIVAAVGRPEMVRGSWLKPGAVVIDVGINRVGDRLVGDVHFEEASAVASAITPVPGGVGPLTIAMLLQNTLMAAKLKTGEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYU5</accession>
    <name>A0A518IYU5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Bifunctional hemolysin/adenylate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">cya_2</name>
        <name evidence="10" type="ORF">Mal33_42840</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.150.10.10">
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039005">
        <property type="entry name" value="CSPG_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025592">
        <property type="entry name" value="DUF4347"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006946">
        <property type="entry name" value="DUF642"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013517">
        <property type="entry name" value="FG-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018511">
        <property type="entry name" value="Hemolysin-typ_Ca-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001343">
        <property type="entry name" value="Hemolysn_Ca-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028994">
        <property type="entry name" value="Integrin_alpha_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011049">
        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14252">
        <property type="entry name" value="DUF4347"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04862">
        <property type="entry name" value="DUF642"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13517">
        <property type="entry name" value="FG-GAP_3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00353">
        <property type="entry name" value="HemolysinCabind"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51120">
        <property type="entry name" value="SSF51120"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69318">
        <property type="entry name" value="SSF69318"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51854">
        <property type="entry name" value="CSPG"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00330">
        <property type="entry name" value="HEMOLYSIN_CALCIUM"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0720">Serine protease</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="DUF4347" evidence="9">
        <location>
            <begin position="164"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="domain" description="DUF642" evidence="8">
        <location>
            <begin position="370"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="3331"/>
            <end position="3362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="31"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF14252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV58266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="3879" mass="401645" checksum="53BB7C1D24E7874B" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYV8</accession>
    <name>A0A518IYV8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Outer membrane efflux protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_42890</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="31"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="148"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="31"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="770" mass="85280" checksum="36A7F0856F22E030" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYY8</accession>
    <name>A0A518IYY8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SASA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_43210</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005181">
        <property type="entry name" value="SASA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03629">
        <property type="entry name" value="SASA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022141317" description="SASA domain-containing protein" evidence="2">
        <location>
            <begin position="25"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="domain" description="SASA" evidence="3">
        <location>
            <begin position="113"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV58303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="403" mass="44602" checksum="F4056E1EEBE907E0" modified="2019-10-16" version="1" precursor="true">MKELIRFAAIFLATSLASSVNVAAAGPPIKVFVLAGQSNMEGHARVETFDYIGDDPATAPLLQKMRNADGTPRIFDDVAISYLTGLGSNNGEGFGKLTAGYGSRRDPARYGGKIGPEFTFGLTMDEAFDQPVLIIKTAWGGKSLYYDFRPPSAGVYQRTQQDIERDRNPESGSGHYYRLMIAHVDRVLADIQRVYPEYDVAQGYELAGFVWFQGFNDMVNRDVYPILPKESSENRFAKYSDWMADFIHDVRKDLDAPQMPFVIGVMGVSGSNANRDNLQFREAMAAPSLLPEFRGNVTAVPTAPFWDEPLAAIQEKRDRVRQMGYLLRTKNKNHANADGTMSEAQQQAYLKEMEAKLITPAEAALWDRGASNAGYHYLGCAKTFALMGVAFADAILQMPPAND</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYZ5</accession>
    <name>A0A518IYZ5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Planctomycete cytochrome C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Mal33_43300</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011429">
        <property type="entry name" value="Cyt_c_Planctomycete-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011444">
        <property type="entry name" value="DUF1549"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022655">
        <property type="entry name" value="DUF1553"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07635">
        <property type="entry name" value="PSCyt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07583">
        <property type="entry name" value="PSCyt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07587">
        <property type="entry name" value="PSD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 4" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome c" evidence="6">
        <location>
            <begin position="65"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="457"/>
            <end position="484"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV58312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="863" mass="96862" checksum="2347DE6FEC98C9BC" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ49</accession>
    <name>A0A518IZ49_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_43770</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="337" mass="36425" checksum="4A9B4F0BADF2F67E" modified="2019-10-16" version="1">MPDCISLKPNVDLGVVPTHLKFVGGLVPDEAGKLPRDADGKLVVVANMAKLCSESLVRISCVQVPFFPGLDEDDVKEMVDGFRELKLQVHFIMMVGGADPMNPEDEDAVVEILVGGLSAAKKHGIETVSSTSVEEWLKPGATRKEGDEFTAAVAQNVRVHSRAFKEAELDGSPVKAWHIEFLRGGEFKTFTDIGRIWTFVEAVNKEIGKSFFKVMVDAAHCGDSTLSIPENEAIIQKIADGDGLGIFHASAKTTRGCLSTDDGWIGALLTACARTGKLKTAFVEVFHHEDAALEGLRNLDPGHGLDTCDGRTYDQVVLDGLTDVARRLNNLSVRGIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ53</accession>
    <name>A0A518IZ53_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Asparagine--tRNA ligase</fullName>
            <ecNumber evidence="5">6.1.1.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Asparaginyl-tRNA synthetase</fullName>
            <shortName evidence="5">AsnRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">asnS</name>
        <name evidence="7" type="ORF">Mal33_43810</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + L-asparagine + tRNA(Asn) = AMP + diphosphate + H(+) + L-asparaginyl-tRNA(Asn)</text>
            <dbReference type="Rhea" id="RHEA:11180"/>
            <dbReference type="Rhea" id="RHEA-COMP:9659"/>
            <dbReference type="Rhea" id="RHEA-COMP:9674"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58048"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78515"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.22"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.22" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004816">
        <property type="term" value="F:asparagine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006421">
        <property type="term" value="P:asparaginyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00534">
        <property type="entry name" value="Asn_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004522">
        <property type="entry name" value="Asn-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002312">
        <property type="entry name" value="Asp/Asn-tRNA-synth_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01042">
        <property type="entry name" value="TRNASYNTHASP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00457">
        <property type="entry name" value="asnS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 5 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="6">
        <location>
            <begin position="136"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV58363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="462" mass="52373" checksum="CE59D7A213EC3249" modified="2019-10-16" version="1">MPLEKMFVSDARDAAHVGKTVLIQGWIRTRRDSKGGFSFLEINDGSCMGNIQVIADADLANYKDEIQRLSAGCSVAIEGEVKASEGKQATEIQASQVTVLGWADDFPLQKKRHSFEKLREWAHIRARSNTFGAVARVRNQICQSIHQFFHENNFLYVHTPIITASDCEGAGEMFKVTTLDLDRLAKSGGPVNYEYDFFDKPSFLTVSGQLEAETYATALGRVYTFGPTFRAENSNTSRHLSEFWMIEPEAAFFDLADDMALAESFLRKILSDVLNRCDEDLQFFDQRIQKGLIESLRKVAETPFQHMTYTDAIKVLENCGESFEFPIAWGTDLQAEHERYLTEKHVAGPLILTDYPSTIKPFYMRLSDDRKTVAAMDVLVPGVGEIIGGSQREERLDVLTQRMAEMDLREEDYWWYLDLRRYGTVPHAGFGLGLERLVQYTTGMANIRDVIPFPRTPGNAEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ75</accession>
    <name>A0A518IZ75_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_43990</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022001652" evidence="2">
        <location>
            <begin position="24"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="182" mass="19614" checksum="B0EFA1FC1E9F0A4E" modified="2019-10-16" version="1" precursor="true">MIRMHHAPLAMAALLLVGGIAAAKEPRGKKHAPDTKRLQGSWIADLEPGLQGRIEFEGSDLRYTHIRGDRKTPIWIGHFAVNEQSDPKQMDWTPLRKAGRGGGQKPVMSNLAIYRLQGDLLLIIGDTQGSRPTAFYSGGGDQRPKTIIFRRSDDSNALDSPPPTGDGASAGAISLSPTPTGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZA6</accession>
    <name>A0A518IZA6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Aspartate kinase</fullName>
            <ecNumber evidence="6">2.7.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">lysC</name>
        <name evidence="15" type="ORF">Mal33_44380</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-aspartate = 4-phospho-L-aspartate + ADP</text>
            <dbReference type="Rhea" id="RHEA:23776"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57535"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.4"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 13">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 1/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 13">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 1/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 13">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 1/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the aspartokinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.4" evidence="6"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00015"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00050">
        <property type="reaction ID" value="UER00461"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00051">
        <property type="reaction ID" value="UER00462"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004072">
        <property type="term" value="F:aspartate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd04261">
        <property type="entry name" value="AAK_AKii-LysC-BS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041740">
        <property type="entry name" value="AKii-LysC-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005260">
        <property type="entry name" value="Asp_kin_monofn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001341">
        <property type="entry name" value="Asp_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018042">
        <property type="entry name" value="Aspartate_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027795">
        <property type="entry name" value="CASTOR_ACT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01842">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13840">
        <property type="entry name" value="ACT_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="SSF53633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00656">
        <property type="entry name" value="asp_kin_monofn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00657">
        <property type="entry name" value="asp_kinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00324">
        <property type="entry name" value="ASPARTOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10 15" id="KW-0418">Kinase</keyword>
    <keyword evidence="12" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 15" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ACT" evidence="14">
        <location>
            <begin position="263"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="domain" description="ACT" evidence="14">
        <location>
            <begin position="453"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
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</entry>
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</entry>
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    </evidence>
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    </evidence>
    <sequence length="477" mass="52890" checksum="78311D163685B653" modified="2019-10-16" version="1">MNQHRTLRIQDRRAFLRGSAWGAAATTVAGMGLPRLGFAETPELTSPASLPTRPAGVQVLMPRDRVPLSFIIDDSTCLVNMGHFCTPQFATAMPNRAEYQKPWRSWPREIPDSFVRQFGEWCAGQGVKGKYSIVPNPACVGWLDRELPGWSRADLQSSLKLVRDLMLPNWDIHPEMITHTRVIDLKTGRPMQQISPATMENSYPQEKKSVDELAAYLAYALRIVKNCDLPCEGITTPGGFGNSMKAELPIAVDQAVRDVYGVDLPHYFKYVISGDESTEPRLEHLRGVGTDDVRLTVNVPAGTGDWFGGWQGDSLSEPDRYCNAAATSGRMVELIQRRQPAVMICHWPGMYSNGSEEGFNSFKRVVESLASRFADDTIWMKVSEIARYWAAKQLTEIRREGNRLTLTAPFAAQRYTLQIAAAAGPVSLQHGNDRTLLSQATRRSTLDAGTWIADEQNLVACFDLPKGTSEVVVGSNA</sequence>
</entry>
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                <person name="Pohl T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
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    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
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            <strain evidence="1 2">Mal33</strain>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
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    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
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    <name>A0A518J046_9BACT</name>
    <protein>
        <submittedName>
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    </protein>
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            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039562">
        <property type="entry name" value="MFP_biotin_lipoyl_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13533">
        <property type="entry name" value="Biotin_lipoyl_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="25"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="domain" description="Biotin_lipoyl_2" evidence="3">
        <location>
            <begin position="64"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="HlyD_D23" evidence="4">
        <location>
            <begin position="257"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="104"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV58665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="440" mass="48323" checksum="E4469974D7D953FD" modified="2019-10-16" version="1">MIELILGTYGAACWLIFKKFKLVPITTYTICTAVLGGMFLLVGLLILLSVCHPVSHDGRFYSTVTQIVPQVRGKVIEVPVTTNAPLKAGDVLFRIDPKPYQLEVDRLEASLAGMNAKVSQLDARLASAQAATEVARSNLLVSESDYDRQARISLEISQAQIEQTQTRLELAKANLERSTELAQSGAASQRELDSDQARVAALEAELLQAKSAEQKAQETLASGGNRLKAARDALKQAEAQEREARVALEAESDGVNPDVRQAMAELERKRWELEQTVLRAPTDGYVTQVTLRPGQMATPFSPNSAMLFIPNEKQMLVARYPQNAIAGIEPGMDAELAFQAYPGRIFPAKVEYVFDIIPEGQFLGAGRVQGGPDASVGDDIPVKFVFGEDVEELNLPTGAHVSIAVYTHNFHALAIVRKIILRIKSWENYVFFMKNFDAVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J054</accession>
    <name>A0A518J054_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_47490</name>
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    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="205" mass="23478" checksum="07FC28192E98513C" modified="2019-10-16" version="1">MIDRAWATGLLSQQIWCWGQDVKRPEGNWLLEIGFERTTPPEHRKECSSVYTLAINDRTRITLRGFGIYIGDDLRGGMFIERYGFTPKYSSTSRLDCPPWSTNDLPDFQLPDAPQRDPTAMLLLDLLDWIRQYELEVVKQLGIDYRRNTLIQWNNGKRPFIPAEQMASSWRKLTIAIAANPDAWISLNAGQPCSAGNRAEEGSEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J072</accession>
    <name>A0A518J072_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_47190</name>
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    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetia</taxon>
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    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="74" mass="8427" checksum="EE7E7EB1A5354A5C" modified="2019-10-16" version="1">MKTFYAATLARYVLVDAADKAEAASLGQDALHTLYADLRAKHGRDIPIEIRTVRLANQAEIDLWNFHRRMEGQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J077</accession>
    <name>A0A518J077_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_47630</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021733751" evidence="1">
        <location>
            <begin position="30"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="275" mass="28731" checksum="E98752A54B9361A1" modified="2019-10-16" version="1" precursor="true">MKRTKSHVQTLAALTLAACSLAGTTPVTAQQTTSASTVSAGPADAALHNAARDGKYLFVYFWKQNDQQTQSMQGVFDQATGQMTDVANAIRVNITDPSNASIVEKFGVSRAPMPLSLAIAPNGAVTQGLPVSFNENQLREAVVSQGTAACLKAMQDRKLVLLFVKQNIDAAAFQGARELTQDERFAASTQIVNIDPSDASEQSFLQSLKVDASAGNGVLVVMTPAGQPVATIAENATKDQIIQRLTAASTSCCPDGKCAPGQQCCPGGNCAPAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J097</accession>
    <name>A0A518J097_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Amylo-alpha-1,6-glucosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_47890</name>
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    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Pirellulaceae</taxon>
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    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035396">
        <property type="entry name" value="Bac_rhamnosid6H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032856">
        <property type="entry name" value="GDE_N_bis"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17389">
        <property type="entry name" value="Bac_rhamnosid6H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14742">
        <property type="entry name" value="GDE_N_bis"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GDE_N_bis" evidence="1">
        <location>
            <begin position="32"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="Bac_rhamnosid6H" evidence="2">
        <location>
            <begin position="372"/>
            <end position="517"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="731" mass="82264" checksum="5A13E043C9685DF9" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0F4</accession>
    <name>A0A518J0F4_9BACT</name>
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    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
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        <lineage>
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            <taxon>Planctomycetes</taxon>
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        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8 9">Mal33</strain>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="ARM-like"/>
    </dbReference>
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        <property type="entry name" value="ARM-type_fold"/>
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    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
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        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
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        <property type="entry name" value="FA58C"/>
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        <property type="match status" value="1"/>
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        <location>
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            <end position="1415"/>
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        </source>
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        <source>
            <dbReference type="EMBL" id="QDV58820.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1581" mass="177056" checksum="D418E45E695F74C9" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0F9</accession>
    <name>A0A518J0F9_9BACT</name>
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        <submittedName>
            <fullName evidence="5">Arylsulfatase</fullName>
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
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                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="PTM">
        <text evidence="1">The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.</text>
    </comment>
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    </dbReference>
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    </dbReference>
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    <proteinExistence type="predicted"/>
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        <location>
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        </location>
    </feature>
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        <location>
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        <location>
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        </location>
    </feature>
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        <location>
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        <source>
            <dbReference type="Pfam" id="PF16347"/>
        </source>
    </evidence>
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            <dbReference type="EMBL" id="QDV58824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="505" mass="56955" checksum="CDF20E430FEA818A" modified="2019-10-16" version="1">MDRDLIYWRQFPFHVFLGPRIASSRLSFDMARLTPLFVLFSLLACFASASADEAKRPNILFLFADDQSYDTVGAFGNEEIQTPSLDELAARGTTFTHCFNMGSWSGAVCVASRTMLNSGRYVWSANAIYAKSEQERQAGRWWSEYLKQAGYKTYMTGKWHVRADAKKSFDDARNVRGGMPQQTPTGYNRPLADGSDPWSPSDPKFGGYWKGGKHWSEVVGDDAIDFIDDAAGQEKPFFMYVAFNAPHDPRQSPQEYVDRYPVDSISVPKDFLPLYPHKDAIGLGPSLRDEALGIFPRTEHCVKVHRQEYYSIITHMDAQIGRILERLKASGVADNTWIFFTADHGLACGHHGLMGKQNMYDHSLRVPFMVVAPGVDAGRRISAPIYLQDVMPTTLQLAGVEKPQHVDFQSVLPLLDGRGQPRQAIYGAYLDLQRSLRTERYKLILYPKAKVARLYDLEQDPDEMNDLAGDAAALPIMRQLFAEFRRQQAELGDSLDLSDTFADLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0U1</accession>
    <name>A0A518J0U1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FecR protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_49840</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="Ferrdict_sens_TM"/>
    </dbReference>
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        <property type="entry name" value="PTHR30273"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="588" mass="64361" checksum="C090229551206B78" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J171</accession>
    <name>A0A518J171_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">HTH-type transcriptional activator RhaS</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rhaS</name>
        <name evidence="3" type="ORF">Mal33_51160</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018062">
        <property type="entry name" value="HTH_AraC-typ_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020449">
        <property type="entry name" value="Tscrpt_reg_HTH_AraC-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00032">
        <property type="entry name" value="HTHARAC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00041">
        <property type="entry name" value="HTH_ARAC_FAMILY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="2">
        <location>
            <begin position="164"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV59091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="277" mass="31569" checksum="C5AD88950DB3C45F" modified="2019-10-16" version="1">MPRHPKQFLYAAIKLVYKSGMKKTASRNRFFERLDPSQQPLALFDLLPDVSFFVKDRRGRFMALNRRGCEYCGVVSEKAAIGKTDHDFFPKTRADTYREDDEQVMSSGEAIVNRIESAPEDAGSPRLVATSKIPLRDRRGRVIGVAGFSRQIERIQSGTADAMAEVIQYIHNHFTEALSSGELATMAGLSVSHFERRFRLAFGASPRQYLIRVRIENAATKLRSSDQSITAIALSCGFYDHAHFSRSFKNLMNMSPSAYRTKTQHVHETKRTERRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1K4</accession>
    <name>A0A518J1K4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_52380</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="80" mass="8950" checksum="20141947604F1D4E" modified="2019-10-16" version="1">MFVKERATGDLVRIDRIDQLANPQSSEVLGWRQAGEEEQGETPFLKSGLAFPSDEPLPQCWCDPHYQCSGDAKQCVPADR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1P9</accession>
    <name>A0A518J1P9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Chaperone protein ClpB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10 13" type="primary">clpB</name>
        <name evidence="13" type="ORF">Mal33_52860</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homohexamer. The oligomerization is ATP-dependent.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homohexamer; The oligomerization is ATP-dependent.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the ClpA/ClpB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042026">
        <property type="term" value="P:protein refolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009408">
        <property type="term" value="P:response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1780.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017730">
        <property type="entry name" value="Chaperonin_ClpB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036628">
        <property type="entry name" value="Clp_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004176">
        <property type="entry name" value="Clp_R_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001270">
        <property type="entry name" value="ClpA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018368">
        <property type="entry name" value="ClpA/B_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028299">
        <property type="entry name" value="ClpA/B_CS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041546">
        <property type="entry name" value="ClpA/ClpB_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17871">
        <property type="entry name" value="AAA_lid_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02861">
        <property type="entry name" value="Clp_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00300">
        <property type="entry name" value="CLPPROTEASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81923">
        <property type="entry name" value="SSF81923"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03346">
        <property type="entry name" value="chaperone_ClpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51903">
        <property type="entry name" value="CLP_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00870">
        <property type="entry name" value="CLPAB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00871">
        <property type="entry name" value="CLPAB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 9" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5 10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0677">Repeat</keyword>
    <keyword evidence="10" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="Clp R" evidence="12">
        <location>
            <begin position="5"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="521"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="413"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00026057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="QDV59258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="892" mass="98524" checksum="BDDBBAC7E4683E7D" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1Q3</accession>
    <name>A0A518J1Q3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_52930</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010980">
        <property type="entry name" value="Cyt_c/b562"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002321">
        <property type="entry name" value="Cyt_c_II"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01322">
        <property type="entry name" value="Cytochrom_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47175">
        <property type="entry name" value="SSF47175"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51009">
        <property type="entry name" value="CYTCII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="311" mass="33789" checksum="076A0C0ECFED2DDD" modified="2019-10-16" version="1">MFRSKSIVFVCLLGLLIAPVIAKERRAKPPRFGADSFRGVFFEDISESVAASRPNVQALRGIRPQVAGAETKDDEETEDVGGAWNKLASAQSIEDEIKRQKLLFDSDVSQPGAFKSGGYVAARTELSILATLFGVVHYYEGDIRWKEQAEAARNLLARTAGNCNSGSIQVFNECKSRKQDLDDLLGGSSLSSPPAATETEWSRIADRSVLMSYLEALSKEKLPDLTNDASGVKDSPDKVKQFSDMVALVGSILIQEGMDEADDEEYVNLSKQMLDAALLVGQAAQKGDADGARKAVGMINQACDACHEQYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1R3</accession>
    <name>A0A518J1R3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Bacterial type II secretion system protein F domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Mal33_53000</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018076">
        <property type="entry name" value="T2SS_GspF_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00482">
        <property type="entry name" value="T2SSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="73"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="116"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="263"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="domain" description="T2SSF" evidence="7">
        <location>
            <begin position="162"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV59272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="310" mass="33786" checksum="59BF868B0795773E" modified="2019-10-16" version="1">MDVVVLVILLLLTPALGVWSWHWISNQSGIGARLAEYRGNRSDDRGKQDPSLDQRRLHGVSGWLYRAGFRSAIAVPAFIASTIILFALGCFVWLQLRTVGTIDVAVDFIRSIPGGVGNVMVPFALATPWFLMVVLTLIPTLLVRSVRRKRVLEIEQDLPLLLDLLNTLSQAGVGFDAALDQILAAGDPERPLAQELRGFQADNLAGRSRIVSLRNLMRRVEIPMFSTFLSAVVQAEQVGAGMGQTLKTQATEMRARRREKATAAAMAVPTLLVVPMVVGFLPGIFVVLLGPMLYQAFGAMGQTLRGVTGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1S0</accession>
    <name>A0A518J1S0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative major pilin subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_53130</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011453">
        <property type="entry name" value="DUF1559"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07596">
        <property type="entry name" value="SBP_bac_10"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="339" mass="36473" checksum="32C5077D02587D7A" modified="2019-10-16" version="1" precursor="true">MKTPHSRLGFTLIELLVVISIIGILVALLLPAVQAAREAARRTDCANRVRQLAVATHMHHDVFRYFPPARYESRPDADPSNQCGLETPTWLARVMPFIEQVSLGDQWDFSKPWHQHDESVRTVVPDIFLCPSRRAGTQPIGTRNLRTTVDGGGGRLPCGCPLPPRTDDVAVNVPGALCDYAGNHGDLTPGSTGAPTDFYYGGNGTGVIISVRPTCKDGKAIGPSDRIRMASVSDGTSSTFLFGEKFVPLDGLAQFPEDSPAYDGDHLPASCRLAGPGLRLASGPRDVLADMFSFGSWHPAGVHFALVDGSVRMFSPTTDTKTLGSLANRGDARVVELQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1Z5</accession>
    <name>A0A518J1Z5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_53870</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="114" mass="12571" checksum="4024BD15F02673C5" modified="2019-10-16" version="1">MWPKVRRAGRQSINVDVGYAASSARAETCREPITQKMWRIDTASCRRKSRRNRLLVGEEKARSTRSGNAVMTPLRQAVGAGKPSGGSAHEKSREPEDSGARGMISTKRCNISQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J231</accession>
    <name>A0A518J231_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">tRNA(Ile)-lysidine synthase</fullName>
            <ecNumber evidence="6">6.3.4.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">tRNA(Ile)-2-lysyl-cytidine synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">tRNA(Ile)-lysidine synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 8" type="primary">tilS</name>
        <name evidence="8" type="ORF">Mal33_54210</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>ATP + cytidine(34) in tRNA(Ile2) + L-lysine = AMP + diphosphate + H(+) + lysidine(34) in tRNA(Ile2)</text>
            <dbReference type="Rhea" id="RHEA:43744"/>
            <dbReference type="Rhea" id="RHEA-COMP:10625"/>
            <dbReference type="Rhea" id="RHEA-COMP:10670"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32551"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="ChEBI" id="CHEBI:83665"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.4.19"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="6">The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the tRNA(Ile)-lysidine synthase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.19" evidence="6"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016879">
        <property type="term" value="F:ligase activity, forming carbon-nitrogen bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01992">
        <property type="entry name" value="PP-ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01161">
        <property type="entry name" value="tRNA_Ile_lys_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011063">
        <property type="entry name" value="TilS/TtcA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012094">
        <property type="entry name" value="tRNA_Ile_lys_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012795">
        <property type="entry name" value="tRNA_Ile_lys_synt_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43033">
        <property type="entry name" value="PTHR43033"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01171">
        <property type="entry name" value="ATP_bind_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02432">
        <property type="entry name" value="lysidine_TilS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 6 8" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="ATP_bind_3" evidence="7">
        <location>
            <begin position="41"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="46"/>
            <end position="51"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV59386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="347" mass="37927" checksum="5C784B356EED6DF0" modified="2019-10-16" version="1">MTALQLHRSSKNRVSETDPLQPICDRVAAVWPVQRWGSLRVVVGVSGGADSVCLVRTLAQMAGGASSNLIVAHYDHQTRDDSADDAAFVGEVARDLGLDFELGRSASRDPSRSEADLRGERYVFLDSVARRLGARYVAVAHNRDDQVETILHNILRGTGGNGARGIAPFRPLGEDLVLARPFLDVSRHSIESAMSAVGQSYRSDPTNAEPTWTRNWLRVELLPLLKAQFPQVDESLLRLGQNVGELQAAVDQMAAELESTAVRYEAGAVRIAVGPMRLTPEAVKVALLQGCWKRMAWPRGKMSHGHWKLLTQRMLGGGAQGKPLSFDLPGEVQVSVSNDEIVLTRRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J2A9</accession>
    <name>A0A518J2A9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Endoribonuclease L-PSP</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_55040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd02199">
        <property type="entry name" value="YjgF_YER057c_UK114_like_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013813">
        <property type="entry name" value="Endoribo_LPSP/chorism_mut-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006175">
        <property type="entry name" value="YjgF/YER057c/UK114"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01042">
        <property type="entry name" value="Ribonuc_L-PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="SSF55298"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="145" mass="15358" checksum="852B23AEB35D135B" modified="2019-10-16" version="1">MSAQQKAIDLGIDLSDQPNGYLNLCIKSGNQLITSGHVSDIKGILGGGLSVEEGYKAARECAEKILRSVRNTHGTLDGLKVVKLLGCVYSAPDFTDQHLVINGASDLFHELYGKDGDGYHARSALGFAALPTGVAVEVEAVFEIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J2E7</accession>
    <name>A0A518J2E7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Bicarbonate transport system permease protein CmpB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">cmpB</name>
        <name evidence="6" type="ORF">Mal33_55440</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="62"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="97"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="125"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="170"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="218"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="55"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV59509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="257" mass="27890" checksum="88287F58CCD6D0AE" modified="2019-10-16" version="1">MLARKILLGTLGIGIFLLIWHLATLGNSRTDVPGPWLAFNGLIELAGQGVLWRYVIASVFRVAWGFFLAAIVGIPLGLAIGWSLWIRELLNPLVQALRPISPIAWLPIAVLVFGGVQWWEPSDLAAIFLIFLASLFPIVTAATSSVAAIDEKYLRAAENFGVRGLPLLRLVILPAALPQILTGLRLAMGIAWVVVVAAEMLGVQSGLGFQINDSRNNLRYDFVVAAMLVISVIGMLLDAAMSRIERTSLARTGMARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IM00</accession>
    <name>A0A518IM00_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ribosomal silencing factor RsfS</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2 4" type="primary">rsfS</name>
        <name evidence="4" type="ORF">Mal33_00700</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Interacts with ribosomal protein L14 (rplN).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the Iojap/RsfS family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042256">
        <property type="term" value="P:mature ribosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090071">
        <property type="term" value="P:negative regulation of ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017148">
        <property type="term" value="P:negative regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01477">
        <property type="entry name" value="Iojap_RsfS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004394">
        <property type="entry name" value="Iojap/RsfS/C7orf30"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21043">
        <property type="entry name" value="PTHR21043"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00090">
        <property type="entry name" value="rsfS_iojap_ybeB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <keyword evidence="2" id="KW-0810">Translation regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV54126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="140" mass="15777" checksum="D0B820F35B1A1A68" modified="2019-10-16" version="1">MSEQAQNEDSQTHPPVSGKQRSLELATAAARVAIENRGSDVMVIDVSDQTVLFDYFVLATGTSRRQLHAISEEIDDVLEKSLNDKRMGIEGYQESRWIVLDYGTIVVHLFDQETRGYYDLESLWADGKPVDLKTLGLQED</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMA1</accession>
    <name>A0A518IMA1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Serine/threonine-protein kinase PknB</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">pknB_1</name>
        <name evidence="3" type="ORF">Mal33_01440</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="154"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="685" mass="74172" checksum="974110994D5C1A84" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMM9</accession>
    <name>A0A518IMM9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_03040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="208" mass="23877" checksum="EC25AAB10BC748A5" modified="2019-10-16" version="1">MAAADWQNDGGRMIKGRIIKGRMITRQDDYSAAMVNIFETFAFLYRSLTLSFCPRSFCQKPGHSQAIAVAASRLRVTPCHRICGLTSAAIRYRRCTAVDGKQEETFPNRDHCFTPCLCERPHAWYQKNLTEAIRHGIFSEMGSWEPFRSAQVFRVVYHVIGSLGFSLRRRCSDRFAAGSSCRRIRHFRRTIARGHETRVVRTAPSRQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMQ4</accession>
    <name>A0A518IMQ4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Anthranilate phosphoribosyltransferase</fullName>
            <ecNumber evidence="3">2.4.2.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3 6" type="primary">trpD</name>
        <name evidence="6" type="ORF">Mal33_03180</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>diphosphate + N-(5-phospho-beta-D-ribosyl)anthranilate = 5-phospho-alpha-D-ribose 1-diphosphate + anthranilate</text>
            <dbReference type="Rhea" id="RHEA:11768"/>
            <dbReference type="ChEBI" id="CHEBI:16567"/>
            <dbReference type="ChEBI" id="CHEBI:18277"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="EC" id="2.4.2.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="3">Binds 2 magnesium ions per monomer.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 2/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the anthranilate phosphoribosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.18" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00041"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004048">
        <property type="term" value="F:anthranilate phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
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        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="term" value="P:tryptophan biosynthetic process"/>
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        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Glycosyl_Trfase_fam3_N_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="Nuc_phospho_transferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43285">
        <property type="entry name" value="PTHR43285"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Glycos_trans_3N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00591">
        <property type="entry name" value="Glycos_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47648">
        <property type="entry name" value="SSF47648"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF52418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01245">
        <property type="entry name" value="trpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="3" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="1 3 6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
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    <keyword evidence="3" id="KW-0822">Tryptophan biosynthesis</keyword>
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        <location>
            <begin position="8"/>
            <end position="67"/>
        </location>
    </feature>
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        <location>
            <begin position="78"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphoribosylpyrophosphate binding" evidence="3">
        <location>
            <begin position="86"/>
            <end position="87"/>
        </location>
    </feature>
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            <begin position="93"/>
            <end position="96"/>
        </location>
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        </location>
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        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
        </ligand>
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    <feature type="binding site" evidence="3">
        <location>
            <position position="95"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>anthranilate</name>
            <dbReference type="ChEBI" id="CHEBI:16567"/>
            <label>1</label>
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    <feature type="binding site" evidence="3">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="169"/>
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        <ligand>
            <name>anthranilate</name>
            <dbReference type="ChEBI" id="CHEBI:16567"/>
            <label>2</label>
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    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="228"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="229"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV54364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="341" mass="34683" checksum="578AFB6111818B0C" modified="2019-10-16" version="1">MSIQIDEAIRTVQAGNDLAADDVQALIGTMLQGEAEDEAIGKLLLALRAKGEVVSELVGAARAMRKHMTPVASAGGILLDTCGTGGDGSGTFNISTAAAIVTAAAGIPVAKHGNRAITSKSGSADVLSALGVNIDTDRDVVERCLAEVGICFCFAPRLHPAMRHVGAIRRQLGVPTLFNLLGPLCNPAAASHQVLGTGKPSTQRQLAEALHQLGTEHAAVVRGLDGLDEVTLDGPTSVIEVTSAGCREIEWTPASFGLSPSGPETMQADGPDESAAIIRQVLGGQPGPARDIVVANAAASIWLCNPEGGLIAAAEQAAAAIDTGQAQRTLEALSAMTSAGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMR3</accession>
    <name>A0A518IMR3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_03310</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="component" value="Chromosome"/>
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        <property type="entry name" value="SSF50939"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <location>
            <begin position="213"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="315"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="611"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="234"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="315"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="377"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="631" mass="68217" checksum="64AF131A29270C2A" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMT7</accession>
    <name>A0A518IMT7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Putative ABC transporter ATP-binding protein YbhF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">ybhF_1</name>
        <name evidence="12" type="ORF">Mal33_03500</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000412">
        <property type="entry name" value="ABC_2_transport"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51012">
        <property type="entry name" value="ABC_TM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 7 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="375"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="540"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="589"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="619"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="650"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="676"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="707"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="6"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="311"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="339"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QDV54396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="734" mass="80750" checksum="3F73022D47244BAC" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ING8</accession>
    <name>A0A518ING8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_05850</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="44"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="115"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="139"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="189"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="226"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="288"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="330"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="743" mass="80463" checksum="73449E2B9FDE2074" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INM7</accession>
    <name>A0A518INM7_9BACT</name>
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        <submittedName>
            <fullName evidence="1">Molybdopterin synthase catalytic subunit</fullName>
            <ecNumber evidence="1">2.8.1.12</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">moaE</name>
        <name evidence="1" type="ORF">Mal33_06410</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.8.1.12" evidence="1"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="GO" id="GO:0030366">
        <property type="term" value="F:molybdopterin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036563">
        <property type="entry name" value="MoaE_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003448">
        <property type="entry name" value="Mopterin_biosynth_MoaE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02391">
        <property type="entry name" value="MoaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54690">
        <property type="entry name" value="SSF54690"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="144" mass="16208" checksum="D3D0795F6AA2806C" modified="2019-10-16" version="1">MLPNAETRVVVELVDGPIESGPILESLSDLDAGAHSLFLGKTRRRTADKETDHLVYDAYRPMALAELRRLADAAADRWQLKRVVVIHRLGRVDLGEASIAIAASSGHRREVFEAIPWLLDEIKSDVPIWKQEHWSDGLTEWVHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INR1</accession>
    <name>A0A518INR1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_06930</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022187105" evidence="1">
        <location>
            <begin position="24"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="142" mass="14854" checksum="1F9558A7A2BB8836" modified="2019-10-16" version="1" precursor="true">MMKNCKSFVASGLLAALSLVTFGCGPSGLPPLGTVHGTVTIDGQPVEGASIEFTPESGRPSVGETDADGNYKMLFTYEADGALVGKHTVRITTARQGVVSEGEGPSIEAREERLPAKYNEASELTVDVVAGDNTFDFDLEGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INW7</accession>
    <name>A0A518INW7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">prkC_1</name>
        <name evidence="8" type="ORF">Mal33_07460</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="77"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV54781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="808" mass="89984" checksum="A8C2B1AB8AFC9FAF" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP11</accession>
    <name>A0A518IP11_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_07960</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021708167" evidence="1">
        <location>
            <begin position="21"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="274" mass="30000" checksum="E3FEFD6B2815B135" modified="2019-10-16" version="1" precursor="true">MYRSLLSLVLLGLATPCVFAQPAATHKTEPTTAEEAAAQKAKEQAELEAKYQAWVATLSPARQAWERTLQSELGGFYLPIHQRQKIAGQANAWDFVEDDPTLPRVLLIGDSVSRAYTETVRKELAGIANVHRAPANCGPTSTGLKKLDIWLGDGKWDLIHFNFGIHDRSTPIADYKSRLEQLVQRMQQTGATVVWASSTPIPDVPGKFTAASMVDRNAAAAEVMKEHSVAIDDLFTAITPRLAELQNPNDVHFTGPGNRFLGQQVAAFLKSQLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP36</accession>
    <name>A0A518IP36_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_07970</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="89" mass="10427" checksum="1F0AE4983471152E" modified="2019-10-16" version="1">MTQNAMQHAVRQTKIERARRMTLDERLAAGAQLYAQQCELVADLIAGLHPDWTTDQVRDEMKRRWKVARERDAKRLYRAGGVEMQDERS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP44</accession>
    <name>A0A518IP44_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hydrogen cyanide synthase subunit HcnC</fullName>
            <ecNumber evidence="3">1.4.99.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">hcnC</name>
        <name evidence="3" type="ORF">Mal33_07990</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; thiamine diphosphate biosynthesis.</text>
    </comment>
    <dbReference type="EC" id="1.4.99.5" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00060"/>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050622">
        <property type="term" value="F:glycine dehydrogenase (cyanide-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009229">
        <property type="term" value="P:thiamine diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012727">
        <property type="entry name" value="Gly_oxidase_ThiO"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02352">
        <property type="entry name" value="thiamin_ThiO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DAO" evidence="2">
        <location>
            <begin position="5"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="373" mass="40215" checksum="36C34E24E2D514DA" modified="2019-10-16" version="1">MQKPDCIVVGGGVIGLSLAWVLAKAGQRIQVIDRQQTGRGTSWAGVGILPPANPQTALDPIERLRALSHQLHPQWAAELLEQTGIDSGYRLCGGIYLAMSRGEQAALLGQADYWSEYDIDAIPLTPAALVELEPALADLSQSDRLQSAWSLPGEAAIRSPDHLAALRAACLQQNVTITESCELTGFRTQADRIEALQTTAGELTAGQYCLTTGAWSQMLLEQLSVPSGLLPVRGQVLLYKLPHQILNRIVNEGNRYLVPRLDGHILVGSNEEEVGFDQSTTPEVLDSLRDWAEGMLPLLAQQPIVRSWSGLRPGSFDGFPYIGKLPNLSNAFVAAGHYRSGLHLSCATATELASLMLGRPTQADLTPFTPGRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPP8</accession>
    <name>A0A518IPP8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MMPL family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Mal33_10440</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004869">
        <property type="entry name" value="MMPL_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03176">
        <property type="entry name" value="MMPL"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="192"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="216"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="243"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="315"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="372"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="586"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="609"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="686"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="712"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="domain" description="MMPL" evidence="7">
        <location>
            <begin position="144"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="domain" description="MMPL" evidence="7">
        <location>
            <begin position="547"/>
            <end position="736"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV55075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="747" mass="81919" checksum="51832F89242F7F99" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPW6</accession>
    <name>A0A518IPW6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA helicase</fullName>
            <ecNumber evidence="3">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">pcrA_2</name>
        <name evidence="9" type="ORF">Mal33_11080</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the helicase family. UvrD subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013986">
        <property type="entry name" value="DExx_box_DNA_helicase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014017">
        <property type="entry name" value="DNA_helicase_UvrD-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000212">
        <property type="entry name" value="DNA_helicase_UvrD/REP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014016">
        <property type="entry name" value="UvrD-like_ATP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11070">
        <property type="entry name" value="PTHR11070"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00580">
        <property type="entry name" value="UvrD-helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13361">
        <property type="entry name" value="UvrD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51198">
        <property type="entry name" value="UVRD_HELICASE_ATP_BIND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51217">
        <property type="entry name" value="UVRD_HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 9" id="KW-0347">Helicase</keyword>
    <keyword evidence="6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UvrD-like helicase ATP-binding" evidence="7">
        <location>
            <begin position="3"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="domain" description="UvrD-like helicase C-terminal" evidence="8">
        <location>
            <begin position="290"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="24"/>
            <end position="31"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV55139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="656" mass="74088" checksum="90B06C60CB301B12" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQ50</accession>
    <name>A0A518IQ50_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">Multifunctional fusion protein</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="6">3-dehydroquinate dehydratase</fullName>
                <shortName evidence="6">3-dehydroquinase</shortName>
                <ecNumber evidence="6">4.2.1.10</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="6">Type I DHQase</fullName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="6">Type I dehydroquinase</fullName>
                <shortName evidence="6">DHQ1</shortName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="7">Shikimate dehydrogenase (NADP(+))</fullName>
                <shortName evidence="7">SDH</shortName>
                <ecNumber evidence="7">1.1.1.25</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="7 12" type="primary">aroE</name>
        <name evidence="6" type="synonym">aroD</name>
        <name evidence="12" type="ORF">Mal33_11700</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).</text>
    </comment>
    <comment type="function">
        <text evidence="6">Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>3-dehydroquinate = 3-dehydroshikimate + H2O</text>
            <dbReference type="Rhea" id="RHEA:21096"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16630"/>
            <dbReference type="ChEBI" id="CHEBI:32364"/>
            <dbReference type="EC" id="4.2.1.10"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>NADP(+) + shikimate = 3-dehydroshikimate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:17737"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16630"/>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.25"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 3/7.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 4/7.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the shikimate dehydrogenase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the type-I 3-dehydroquinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.10" evidence="6"/>
    <dbReference type="EC" id="1.1.1.25" evidence="7"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00086"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003855">
        <property type="term" value="F:3-dehydroquinate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004764">
        <property type="term" value="F:shikimate 3-dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046279">
        <property type="term" value="P:3,4-dihydroxybenzoate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019632">
        <property type="term" value="P:shikimate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00502">
        <property type="entry name" value="DHQase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00214">
        <property type="entry name" value="AroD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00222">
        <property type="entry name" value="Shikimate_DH_AroE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminiacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001381">
        <property type="entry name" value="DHquinase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041121">
        <property type="entry name" value="SDH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011342">
        <property type="entry name" value="Shikimate_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013708">
        <property type="entry name" value="Shikimate_DH-bd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022893">
        <property type="entry name" value="Shikimate_DH_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006151">
        <property type="entry name" value="Shikm_DH/Glu-tRNA_Rdtase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21089">
        <property type="entry name" value="PTHR21089"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01487">
        <property type="entry name" value="DHquinase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18317">
        <property type="entry name" value="SDH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01488">
        <property type="entry name" value="Shikimate_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08501">
        <property type="entry name" value="Shikimate_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="SSF53223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00507">
        <property type="entry name" value="aroE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4 6" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-0521">NADP</keyword>
    <keyword evidence="7 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0704">Schiff base</keyword>
    <feature type="domain" description="Shikimate_dh_N" evidence="10">
        <location>
            <begin position="247"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="domain" description="Shikimate_DH" evidence="9">
        <location>
            <begin position="363"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="domain" description="SDH_C" evidence="11">
        <location>
            <begin position="481"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="region of interest" description="3-dehydroquinate binding" evidence="6">
        <location>
            <begin position="54"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Shikimate binding" evidence="7">
        <location>
            <begin position="255"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="517"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="6">
        <location>
            <position position="135"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate" evidence="6">
        <location>
            <position position="160"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="306"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="29"/>
        </location>
        <ligand>
            <name>3-dehydroquinate</name>
            <dbReference type="ChEBI" id="CHEBI:32364"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>3-dehydroquinate</name>
            <dbReference type="ChEBI" id="CHEBI:32364"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>3-dehydroquinate</name>
            <dbReference type="ChEBI" id="CHEBI:32364"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="223"/>
        </location>
        <ligand>
            <name>3-dehydroquinate</name>
            <dbReference type="ChEBI" id="CHEBI:32364"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="302"/>
        </location>
        <ligand>
            <name>shikimate</name>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="327"/>
        </location>
        <ligand>
            <name>shikimate</name>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="342"/>
        </location>
        <ligand>
            <name>shikimate</name>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="373"/>
            <end position="377"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="458"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="460"/>
        </location>
        <ligand>
            <name>shikimate</name>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="481"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="488"/>
        </location>
        <ligand>
            <name>shikimate</name>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF18317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QDV55200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="537" mass="59743" checksum="F70C9CD79B4AA8C0" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQ84</accession>
    <name>A0A518IQ84_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">3-deoxy-manno-octulosonate cytidylyltransferase</fullName>
            <ecNumber evidence="2">2.7.7.38</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">CMP-2-keto-3-deoxyoctulosonic acid synthase</fullName>
            <shortName evidence="2">CKS</shortName>
            <shortName evidence="2">CMP-KDO synthase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">kpsU</name>
        <name evidence="2" type="synonym">kdsB</name>
        <name evidence="3" type="ORF">Mal33_12310</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>3-deoxy-alpha-D-manno-oct-2-ulosonate + CTP = CMP-3-deoxy-beta-D-manno-octulosonate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:23448"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:85986"/>
            <dbReference type="ChEBI" id="CHEBI:85987"/>
            <dbReference type="EC" id="2.7.7.38"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Nucleotide-sugar biosynthesis; CMP-3-deoxy-D-manno-octulosonate biosynthesis; CMP-3-deoxy-D-manno-octulosonate from 3-deoxy-D-manno-octulosonate and CTP: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the KdsB family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.38" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00358">
        <property type="reaction ID" value="UER00476"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008690">
        <property type="term" value="F:3-deoxy-manno-octulosonate cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033468">
        <property type="term" value="P:CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009103">
        <property type="term" value="P:lipopolysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02517">
        <property type="entry name" value="CMP-KDO-Synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00057">
        <property type="entry name" value="KdsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003329">
        <property type="entry name" value="Cytidylyl_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004528">
        <property type="entry name" value="KdsB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02348">
        <property type="entry name" value="CTP_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00466">
        <property type="entry name" value="kdsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2" id="KW-0448">Lipopolysaccharide biosynthesis</keyword>
    <keyword evidence="2 3" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="252" mass="27895" checksum="11A6B6C31786C366" modified="2019-10-16" version="1">MLNAKIVIPARLASTRLPEKLLRVVAGKSILQRTYEAASRSRRAASMIVAVDDPRLLAEVERFGGNAMMTSVDCQSGTDRVAEAALADDQADVFVNVQGDEPEIDPDAIDLVVDLLEQHPEAYAATLATPIRDAADLKNPNCVKVVLETGGYALYFSRSPIPLPRDQDFQALVDHDPPLCWQHIGLYAYRREVLQWFTQQAPSPLELTERLEQLRLLEAGRRIVVGKIDHPAIGIDTEEDLQAFERKLGTDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQC8</accession>
    <name>A0A518IQC8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Transcriptional regulatory protein ZraR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">zraR_4</name>
        <name evidence="10" type="ORF">Mal33_12790</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002197">
        <property type="entry name" value="HTH_Fis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002078">
        <property type="entry name" value="Sigma_54_int"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025943">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025944">
        <property type="entry name" value="Sigma_54_int_dom_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02954">
        <property type="entry name" value="HTH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00158">
        <property type="entry name" value="Sigma54_activat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01590">
        <property type="entry name" value="HTHFIS"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00676">
        <property type="entry name" value="SIGMA54_INTERACT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00688">
        <property type="entry name" value="SIGMA54_INTERACT_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50045">
        <property type="entry name" value="SIGMA54_INTERACT_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Response regulatory" evidence="9">
        <location>
            <begin position="6"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma-54 factor interaction" evidence="8">
        <location>
            <begin position="145"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="386"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="386"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="6">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV55308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="479" mass="53233" checksum="6959B412369AC5E4" modified="2019-10-16" version="1">MTLNPKLLLVDDDRRLAESMADWLRFQQFNVDQAHSLAGGRRAIQEQTYDLMLLDLRLEDGDGFALIAETKRRQPDCAILVLTGYATPNTAIEAVQAGAFDLLTKPLVDEELSHALERALAQQNIQAENEKLRAQLDSRFGLEHILSHDYRMLKIFDVIDSVADARASVLITGENGTGKSMIARAVHKRSNRRNNPFVEVACGALPDNLLESELFGHVIGSFTGATTNKVGKFKQADGGTIFLDEIGTASQAFQVKLLRVLQELQFEPLGGTETETVDTRVILATNENLAQAVSSGQFRQDLFYRVNVINIELPALRERSGDVPLLVDHFLREVCETTGRDVQGFDRDALAILQSYAWPGNVRELENVVERAVLLARDSVLTRNDLPPHLLSSSTNPRTASDSFDSPSTLSSDSGSGQTLREALEEPERRIILESLRLHNWNRAATADTLGVNRTTLYKKMKRLGLDDPRLQFMGAEAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQE6</accession>
    <name>A0A518IQE6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Response regulator protein VraR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">vraR_1</name>
        <name evidence="5" type="ORF">Mal33_12780</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="5"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="145"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV55307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="212" mass="22628" checksum="DA5066C1C1D50B53" modified="2019-10-16" version="1">MKSLDVVIIDDHEVVRSGITSLLSGPEVTVIGSAASGQEGLELMSKQLPDAVLLDIRMPDNDGLSTLQTLRASHPDLPIVMVSTYDNPTYVARSVALGANDYVLKGDSRSVFLDALTRAASGEEPSSDSLLRKIGESMSRSGKEAPPMDVPLTAREVQVLRHVALGLSNKEIGCSLNISVETVKEHVQNILRKLNAADRTDAAVRAVKMGLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQH4</accession>
    <name>A0A518IQH4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_13170</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="120" mass="13384" checksum="77252297177B1E5C" modified="2019-10-16" version="1">MSHIVEIDAEIRDADALRLACRRNKLAAPVQGTAKLFSSEATGYLVHLPRWRYPVVCDTDSGNVAYDNYEGHWGDQSDLDKLLQSYSTEKCKLEARRQGHTVTEQTLSNGSIKLTVCVGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQR4</accession>
    <name>A0A518IQR4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_14090</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="121"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="184"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="218"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="242"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="269"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="344"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="378"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="409"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="435"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="485"/>
            <end position="507"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="515" mass="57776" checksum="E269DF5199A409C1" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQS5</accession>
    <name>A0A518IQS5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC</fullName>
            <ecNumber evidence="5">3.1.3.45</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_14210</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the KdsC family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.45" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019143">
        <property type="term" value="F:3-deoxy-manno-octulosonate-8-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010023">
        <property type="entry name" value="KdsC_fam"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006118">
        <property type="entry name" value="KDO8-P_Ptase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01138">
        <property type="entry name" value="C1.6.2:_Deoxy-d-mannose-octulo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01670">
        <property type="entry name" value="KdsC-phosphatas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="4">
        <location>
            <position position="17"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="19"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR006118-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV55447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="172" mass="18655" checksum="1093697ABB6F86EE" modified="2019-10-16" version="1">MKSDSEIAAPIKLILSDVDGVLTNGQIIYDAAGFETKAFHVRDGLGIKLWQRAGFSFGIITARNSEIVTRRAEELGITGLRQGCQQKWDAAVELMQEAGCGPEQTAYIGDDLPDLAVMTRVALPVCVSDAASDVRKAATWITKLPGGTGAVREMIERLLHAKSKWDSLVVQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQW0</accession>
    <name>A0A518IQW0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_14570</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="124" mass="13956" checksum="EB42E72505716A98" modified="2019-10-16" version="1">MEIVAPKTTLPTGWHHVESLDAGPRRSKAYRDLQALAECYRREFDREADSARNYSGLADSSHWIQSITHGDGTNRIAAAVACICPNGEWRIYWSWQHPFRRLHHAGDLAQGVELAQAMAGQVSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IR53</accession>
    <name>A0A518IR53_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_15510</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026406">
        <property type="entry name" value="Ver/Plancto_CHP"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04138">
        <property type="entry name" value="Plancto_Ver_chp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="135" mass="15811" checksum="21EFFBAF30134EC0" modified="2019-10-16" version="1">MNTGIRAFADLLEHDQRFKFEAYQFVRESLSYAHDVLRVSDDPAFSDEESRHLTGQQLCEACRRYALEQYGFLAKLVLNDWGIYTTSDLGEIVYNLIRIEQMRKSDSDRREDFDDVFVFETAFEPEFESLSTGQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRD2</accession>
    <name>A0A518IRD2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Methylated-DNA--protein-cysteine methyltransferase</fullName>
            <ecNumber evidence="8">2.1.1.63</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">6-O-methylguanine-DNA methyltransferase</fullName>
            <shortName evidence="8">MGMT</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">O-6-methylguanine-DNA-alkyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">ada</name>
        <name evidence="12" type="ORF">Mal33_16010</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>a 4-O-methyl-thymidine in DNA + L-cysteinyl-[protein] = a thymidine in DNA + S-methyl-L-cysteinyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:53428"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:10132"/>
            <dbReference type="Rhea" id="RHEA-COMP:13555"/>
            <dbReference type="Rhea" id="RHEA-COMP:13556"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:82612"/>
            <dbReference type="ChEBI" id="CHEBI:137386"/>
            <dbReference type="ChEBI" id="CHEBI:137387"/>
            <dbReference type="EC" id="2.1.1.63"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 8">
            <text>a 6-O-methyl-2'-deoxyguanosine in DNA + L-cysteinyl-[protein] = a 2'-deoxyguanosine in DNA + S-methyl-L-cysteinyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:24000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:10132"/>
            <dbReference type="Rhea" id="RHEA-COMP:11367"/>
            <dbReference type="Rhea" id="RHEA-COMP:11368"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:82612"/>
            <dbReference type="ChEBI" id="CHEBI:85445"/>
            <dbReference type="ChEBI" id="CHEBI:85448"/>
            <dbReference type="EC" id="2.1.1.63"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="10">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="8">This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the MGMT family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.63" evidence="8"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003908">
        <property type="term" value="F:methylated-DNA-[protein]-cysteine S-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006307">
        <property type="term" value="P:DNA dealkylation involved in DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06445">
        <property type="entry name" value="ATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00772">
        <property type="entry name" value="OGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035451">
        <property type="entry name" value="Ada-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004026">
        <property type="entry name" value="Ada_DNA_repair_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016221">
        <property type="entry name" value="Bifunct_regulatory_prot_Ada"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001497">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014048">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036217">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_DNAb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008332">
        <property type="entry name" value="MethylG_MeTrfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023546">
        <property type="entry name" value="MGMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036631">
        <property type="entry name" value="MGMT_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02805">
        <property type="entry name" value="Ada_Zn_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01035">
        <property type="entry name" value="DNA_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02870">
        <property type="entry name" value="Methyltransf_1N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000409">
        <property type="entry name" value="Ada"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46767">
        <property type="entry name" value="SSF46767"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53155">
        <property type="entry name" value="SSF53155"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57884">
        <property type="entry name" value="SSF57884"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00589">
        <property type="entry name" value="ogt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00374">
        <property type="entry name" value="MGMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7 8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="11">
        <location>
            <begin position="98"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile; methyl group acceptor from methylphosphotriester" evidence="9">
        <location>
            <position position="27"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile; methyl group acceptor" evidence="8">
        <location>
            <position position="308"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile; methyl group acceptor from either O6-methylguanine or O4-methylthymine" evidence="9">
        <location>
            <position position="308"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="27"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="31"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000409-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000409-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QDV55624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="345" mass="38321" checksum="6101D17979E3B214" modified="2019-10-16" version="1">MYAALVAKDSRFEGVFLAGIRTTGIFCRPSCTARKPKPENVEYFRDAKSAMAHGFRACKVCRPLAALGASPDWLQPLIDDLQRDANLRLRSEDLRSRGLDPARVRRWFQKTHGMTFTAYQRMRRINQAFGQIRERQSVTEVALQSGYESLSGFGDGFKRAIGAAPAKSDGRQVIAISRLLTPLGPMLAGASDAGICLLEFADRPMLETQLDRLRKRRGATLLPGPSPLFATLQSQLQEYFAGRRTRFEIPLDTTGTPFQQRVWEALRQIPFGETRSYAQQATAIGKPTAVRAVARANGDNRIAILIPCHRVIGADGTLTGYGGGLWRKQRLLEIERQQPAKTGQC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRV6</accession>
    <name>A0A518IRV6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Uracil phosphoribosyltransferase</fullName>
            <ecNumber evidence="4">2.4.2.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">UMP pyrophosphorylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">upp</name>
        <name evidence="11" type="ORF">Mal33_17620</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Pyrimidine metabolism; UMP biosynthesis via salvage pathway; UMP from uracil: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the UPRTase family.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.9" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00574">
        <property type="reaction ID" value="UER00636"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004845">
        <property type="term" value="F:uracil phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044206">
        <property type="term" value="P:UMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006223">
        <property type="term" value="P:uracil salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005765">
        <property type="entry name" value="Ura_phspho_trans"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01091">
        <property type="entry name" value="upp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="6 11" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QDV55783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="209" mass="22725" checksum="E77A78EB0511EEF2" modified="2019-10-16" version="1">MGRLNQLSHPLVAHHLATMRDEKTSPAEFRATVSRLAMLLGVYATEDLPTAATTVRTPLADCPSQTLAVRVGLVPILRAGLGLVEPLHQLIPDAEVWHLGMYRNEETAEPVSYYDKLPSRDAVDVALVLDPMLATGGSIRSAVERLIRWGVPDIRVLSVIAARPGLERVQAEFPDVSIFVCAVDPSLNDQQFIVPGLGDAGDRIFNTVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRX0</accession>
    <name>A0A518IRX0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TadE-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_18000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012495">
        <property type="entry name" value="TadE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07811">
        <property type="entry name" value="TadE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="147" mass="15967" checksum="AEC42AD63D2A3174" modified="2019-10-16" version="1">MYRSNRKSQRTGAAVVEMAICLPVLIALTVATIDVCSVMFLKESLSIAAYEGARIGVARGGTNAQATARVKEILDERGITYNNGNVVQIQRTDSPTNGGFNSAETLEHCRILVQVPASGNVLSPAKLFTSGNIQSFVWMRKEYENID</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRX6</accession>
    <name>A0A518IRX6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Bacterial type II/III secretion system short domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_18240</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.120">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005644">
        <property type="entry name" value="NolW-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038591">
        <property type="entry name" value="NolW-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03958">
        <property type="entry name" value="Secretin_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Secretin_N" evidence="2">
        <location>
            <begin position="297"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="domain" description="Secretin_N" evidence="2">
        <location>
            <begin position="729"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="610"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="861"/>
            <end position="893"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="963"/>
            <end position="1005"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="613"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="654"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="974"/>
            <end position="1005"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1005" mass="111005" checksum="6F3CB14676FC1DE8" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IS10</accession>
    <name>A0A518IS10_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RNA polymerase sigma factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_18650</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="2">
        <location>
            <begin position="59"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="3">
        <location>
            <begin position="158"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV55886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="225" mass="25846" checksum="BAED575A7568A8AA" modified="2019-10-16" version="1">MSPLIDLSPRGKRKGEGIFFSISCLRFVDDGNSRCEPTDFTPLLLVDRVSIIADEIHELLDRHRPWLLRVIQARTTLASAVEDVYSEVLLAIAKSDHRPRDDSSLAPWLCKIAIRQSALANRTAMRRDRLNKDYAHQSPDSPAANDPIFWLMDQERRDLVRQVLHEMEPDVRGVLLAKFVEKLTYPQLAQRLGVAEHVVQYRVAQAKKRLRQMLTQRGIDQEDLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IS21</accession>
    <name>A0A518IS21_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">UDP-glucose:undecaprenyl-phosphate glucose-1-phosphate transferase</fullName>
            <ecNumber evidence="9">2.7.8.31</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">wcaJ_1</name>
        <name evidence="9" type="ORF">Mal33_18500</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bacterial sugar transferase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.31" evidence="9"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003362">
        <property type="entry name" value="Bact_transf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017475">
        <property type="entry name" value="EPS_sugar_tfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017473">
        <property type="entry name" value="Undecaprenyl-P_gluc_Ptfrase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02397">
        <property type="entry name" value="Bac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03025">
        <property type="entry name" value="EPS_sugtrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03023">
        <property type="entry name" value="WcaJ_sugtrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="16"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="45"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="78"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="105"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="280"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="Bac_transf" evidence="8">
        <location>
            <begin position="278"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV55871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="468" mass="52381" checksum="2B0570F8A96E751B" modified="2019-10-16" version="1">MQSITPIRPRQRSIEFLRLLIDGAAIIGTLAIVKGLSPGWFDNQAIVAGLTAILAFLLLGHVTGLYRAGLDMTANQEVVRVTTTWVLTMAVIAGLAFFARYGQHFARSVVLGWCIMAPVMICLIRMIWRVCQRMLLKQGIGTRRVAIAGLNDLGLQVSRNIEQSPGLGFQLTGFYDDRDRERRSELGPNDPQLLGKIDDLILAAQNNEFDIVMISLPMRAEERIKFILEKLSDSTASVYIVPDFFVFELMHSQWTNMGGIPAVSVFESPLYGVDGVSKRLVDIAVTISALVAAAIPMLMIAAAIKLTSPGPVFFRQRRYGVDGREILVWKFRSMTTCDNGSVVRQATKGDARITPLGAILRKTSLDELPQLFNVLEGSMSLVGPRPHASAHNEHYRGQIRGYMLRHKIKPGITGLAQVEGCRGETDTLDKMQRRVDFDHRYIRDWSLWLDIRILFKTLLVAWRQPEAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISC1</accession>
    <name>A0A518ISC1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_19500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="14"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="155" mass="16722" checksum="D446A4976F6C5460" modified="2019-10-16" version="1">MRPGPSLSGPKTTLLLYGLIIATITIVVGSTVWMGQASDQPLPVKAELDQRMVDVPDGSGARLTDVIVLTNLSGDALPKIDISINAQYFLYRDSPLAPHEELVLPQSIFSTKSSLRFNPDNYPIQTITVTGRLPSGARGVYEMVIEDAASHATEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISD6</accession>
    <name>A0A518ISD6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Isoleucine--tRNA ligase</fullName>
            <ecNumber evidence="8">6.1.1.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Isoleucyl-tRNA synthetase</fullName>
            <shortName evidence="8">IleRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 11" type="primary">ileS</name>
        <name evidence="11" type="ORF">Mal33_19520</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 8">Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + L-isoleucine + tRNA(Ile) = AMP + diphosphate + L-isoleucyl-tRNA(Ile)</text>
            <dbReference type="Rhea" id="RHEA:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:9666"/>
            <dbReference type="Rhea" id="RHEA-COMP:9695"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58045"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78528"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="8">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="8">IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.5" evidence="8"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA editing activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004822">
        <property type="term" value="F:isoleucine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006428">
        <property type="term" value="P:isoleucyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07961">
        <property type="entry name" value="Anticodon_Ia_Ile_ABEc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02003">
        <property type="entry name" value="Ile_tRNA_synth_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033709">
        <property type="entry name" value="Anticodon_Ile_ABEc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002301">
        <property type="entry name" value="Ile-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023586">
        <property type="entry name" value="Ile-tRNA-ligase_type2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42780">
        <property type="entry name" value="PTHR42780"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00984">
        <property type="entry name" value="TRNASYNTHILE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="SSF50677"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00392">
        <property type="entry name" value="ileS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 8 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="tRNA-synt_1" evidence="9">
        <location>
            <begin position="17"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="domain" description="Anticodon_1" evidence="10">
        <location>
            <begin position="778"/>
            <end position="936"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="8">
        <location>
            <begin position="48"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="8">
        <location>
            <begin position="674"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="677"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QDV55973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1156" mass="131526" checksum="62CB7BB6A421A03A" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISH3</accession>
    <name>A0A518ISH3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">von Willebrand factor type A domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_20170</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010768">
        <property type="entry name" value="GATase1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07090">
        <property type="entry name" value="GATase1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13519">
        <property type="entry name" value="VWA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="43"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="3">
        <location>
            <begin position="70"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="947"/>
            <end position="1014"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="961"/>
            <end position="984"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="991"/>
            <end position="1014"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV56038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1014" mass="110370" checksum="A4775A128A67C86D" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISH5</accession>
    <name>A0A518ISH5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PrkA AAA domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_20260</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013153">
        <property type="entry name" value="Prk_AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010650">
        <property type="entry name" value="PrkA_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016230">
        <property type="entry name" value="Ser_kinase_PrkA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08298">
        <property type="entry name" value="AAA_PrkA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06798">
        <property type="entry name" value="PrkA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000549">
        <property type="entry name" value="Ser_prot_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00763">
        <property type="entry name" value="AAA_PrkA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_PrkA" evidence="1">
        <location>
            <begin position="25"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="650" mass="74378" checksum="A3BF5CC0A11FF410" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISN3</accession>
    <name>A0A518ISN3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_20590</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="65" mass="7098" checksum="1500885D225266D8" modified="2019-10-16" version="1">MRLKQQAVVDFRYGPGVIRSVSEQLGRQTAYCEGGFVGKACLRGGFLFWHINCIEPDSAIHGGGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISS1</accession>
    <name>A0A518ISS1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Elongation factor P</fullName>
            <shortName evidence="7">EF-P</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 11" type="primary">efp</name>
        <name evidence="11" type="ORF">Mal33_21140</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Protein biosynthesis; polypeptide chain elongation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7 8">Belongs to the elongation factor P family.</text>
    </comment>
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        <property type="protein sequence ID" value="QDV56135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00345"/>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04470">
        <property type="entry name" value="S1_EF-P_repeat_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05794">
        <property type="entry name" value="S1_EF-P_repeat_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00141">
        <property type="entry name" value="EF_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015365">
        <property type="entry name" value="Elong-fact-P_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_L2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020599">
        <property type="entry name" value="Transl_elong_fac_P/YeiP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013185">
        <property type="entry name" value="Transl_elong_KOW-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001059">
        <property type="entry name" value="Transl_elong_P/YeiP_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013852">
        <property type="entry name" value="Transl_elong_P/YeiP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011768">
        <property type="entry name" value="Transl_elongation_fac_P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30053">
        <property type="entry name" value="PTHR30053"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01132">
        <property type="entry name" value="EFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08207">
        <property type="entry name" value="EFP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09285">
        <property type="entry name" value="Elong-fact-P_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005901">
        <property type="entry name" value="EF-P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01185">
        <property type="entry name" value="EFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00841">
        <property type="entry name" value="Elong-fact-P_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00038">
        <property type="entry name" value="efp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01275">
        <property type="entry name" value="EFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7 11" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="6 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EFP" evidence="10">
        <location>
            <begin position="69"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="Elong-fact-P_C" evidence="9">
        <location>
            <begin position="131"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QDV56135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="189" mass="21151" checksum="C55DA6C8D4684BB4" modified="2019-10-16" version="1">MANYNTSDFRKGLKVQIDGEPYLMTEMNFVKPGKGNAMYKCRLKNLVRGTSLDRTYKGGDSLESADVEEIDTQFLYRQGDGFVFMDSKTYEQYELTADQVDDAWKYLKDGITCTVTLYNGNPIVMSPPNHVEMEIIECQPGAKGDTATNVTKPAKVETGAEITVPGFIKEGNVIKIDTRTGEYIERVSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IT08</accession>
    <name>A0A518IT08_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RNA polymerase sigma factor SigZ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_22100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011517">
        <property type="entry name" value="RNA_pol_sigma70_ECF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07638">
        <property type="entry name" value="Sigma70_ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="105"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="197" mass="22607" checksum="17AD770408C7C5E0" modified="2019-10-16" version="1">MEFGHTQRLGQWLDLARQGQVDARNEIIAHACERLRLLTRKMLKNYPKVKRWSETDDVLQNAMIRLHRSLAEIQPETPRQFYGLATTQIRRELIDLARHHYGAHGNGANHLTDGGEAANQKSDGREPESLDSWSKFHEAVEGLPEEQREVVNLLWYEGISQPDAAKLLGISLATLKRRWQSARITLGKLIEEIQLVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IT28</accession>
    <name>A0A518IT28_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_22340</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="432" mass="49913" checksum="76A4CE893C960B0F" modified="2019-10-16" version="1">MSQSHIKTKEVKTLFAHSGNQCAYPKCKQRLVEPATKHDGAAVIGKIAHIIADSHDGPRGRVAISDDDKNLHPNLVLLCGNHHDLVDAQPNTFSVQVLRQMKADHELNVQRALFADDGPEKPTLTNEVIHSSLLPITHLPDAMFSAPCKFSDQEYDHVFDRIVYPDNRDELVRFVLREGKLFTFHNLNNPQGPFSKVVDRKQVQPLEALKVWDDPELRRRYVTLLNRGLNRFTSLLGMRFDRDHYRYYFEAKEKEKPRKVSYRPLNAKRTSRDVVWQPKKRATNEARNYWFHLAVGLKFHQMDADQWVLSLRPERRITTDTVTSIESTIIGSRVTRRKARMWNDIYLSEINFWRDYLSGGTPRIVLNFGDQSAVIEATLTAFDVEWPGIPGDDKSFKNQTYEEDLFTQLDFDNAVSGSSIDWDECDDNTEEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IT31</accession>
    <name>A0A518IT31_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HTH-type transcriptional repressor RghR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rghR_1</name>
        <name evidence="2" type="ORF">Mal33_22360</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="9"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="111" mass="12670" checksum="1F7BEF4C425C57A6" modified="2019-10-16" version="1">MPKTFGETVRDIRKNQQLSQRDLAGKVGVSFTYISKIENEKLDFGDYPSEELIRKLANALNTDADQLMILAKKVPDRIKQRVMERPDAFRKIADLDDEKLDQLLDDMGEGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IT49</accession>
    <name>A0A518IT49_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DSBA-like thioredoxin domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_22560</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001853">
        <property type="entry name" value="DSBA-like_thioredoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01323">
        <property type="entry name" value="DSBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DSBA" evidence="1">
        <location>
            <begin position="5"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="210" mass="23453" checksum="047D7C67A57BDBC2" modified="2019-10-16" version="1">MNLAVDVISDVICPWCFIGKRRLEKAIAAVDGQYDVQVNWHPFQLNPAMPKEGISRKEYRTRKFGSWERSLQLDAKVIAVGESEGIHFDFDKTEKTPNTVDAHRLIWLADQHGCQDAVVEAMFRAYFTEGKDIGNRQTLMDVTAEAGLNRQASEDMLNSDDGMEVISNGSEMSQQHQVDGVPFFIINNAVTLSGAQAPETFLDAFKQAIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IT83</accession>
    <name>A0A518IT83_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Spondin_N</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_22840</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2130">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002105">
        <property type="entry name" value="Dockerin_1_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036439">
        <property type="entry name" value="Dockerin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038678">
        <property type="entry name" value="Spondin_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00404">
        <property type="entry name" value="Dockerin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63446">
        <property type="entry name" value="SSF63446"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1419" mass="146689" checksum="1F0D6ECD047572DE" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITN4</accession>
    <name>A0A518ITN4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_24420</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="223"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="245" mass="25697" checksum="57440B16F5477A8A" modified="2019-10-16" version="1">MCPQHQEPPLNHTACPKCHREVDDRAVGCPHCGERIYVEVPGGITPTRHPPMEFPENAATMTPKQAPPTDAEPEANPQNDAEYCVIAEFDNRDDFATALRVLEKAGYTRDEVSTITRVTDPSFAQLSGSGKETGVQPPGSKTTGVGALIGGALGGLLGTATMVGPMLLAGPIVGMAAGAVGGSVWSAMENHGVQEEDASGYAARVRDGALLIVVTGPEVRVREASNSLQTVGPRSLERYDNPAAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITQ7</accession>
    <name>A0A518ITQ7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">EcoKI restriction-modification system protein HsdS</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_24610</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the type-I restriction system S methylase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="REBASE" id="355354">
        <property type="entry name" value="S.PbaMal33ORF24600P"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.220.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000055">
        <property type="entry name" value="Restrct_endonuc_typeI_TRD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044946">
        <property type="entry name" value="Restrct_endonuc_typeI_TRD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01420">
        <property type="entry name" value="Methylase_S"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0680">Restriction system</keyword>
    <feature type="domain" description="Methylase_S" evidence="4">
        <location>
            <begin position="21"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="Methylase_S" evidence="4">
        <location>
            <begin position="239"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV56471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="423" mass="47491" checksum="5EE246A1A486898A" modified="2019-10-16" version="1">MSFPAYEEYNDSGVDWLGRVPDHWDVVPLKFLVATRGGGTPSKTNKKYWDNGLVPWASSKDLKVELLDDTIDHITQFAVEDDAAELVDAGSLLVVVRGMILAHTFPVVKLLVPMAINQDLKALTPKEQLDPDYLSWMLRGSSRETLDRVDEAAHGTKVLRMDSWLRTLFAIPPLDEQEAISAFLDVETAKIDALVSEQRRLIELLKEKRQAVISHAVTKGLNPEAPMKPSGIPWPIEIPEHWEVSQLRRKMELQRGVDITKDEQIEGDVPVVSSGGISSYHNQAIVDAPGVVLGRKGSVGSIHYIEKDYWPHDTTLYVKEFRGNLPRFLYYKMCSMDLASYDTGSSNPTLNRNVLHPVRVPWPPLYEQEEIVEHLDSVFAEFDTLEAEAGLAIELLQERRTALISAAVTGKIDVRAFANRETT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITT5</accession>
    <name>A0A518ITT5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phage Terminase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_24950</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005021">
        <property type="entry name" value="Terminase_largesu_Lambdalike"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41287">
        <property type="entry name" value="PTHR41287"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03354">
        <property type="entry name" value="Terminase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="545"/>
            <end position="564"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="597" mass="68054" checksum="DB9CEA30B60D1CE5" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IU29</accession>
    <name>A0A518IU29_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Flagellar biosynthetic protein FlhB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">flhB</name>
        <name evidence="3" type="ORF">Mal33_25810</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1690.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006135">
        <property type="entry name" value="T3SS_substrate_exporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029025">
        <property type="entry name" value="T3SS_substrate_exporter_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30531">
        <property type="entry name" value="PTHR30531"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01312">
        <property type="entry name" value="Bac_export_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00950">
        <property type="entry name" value="TYPE3IMSPROT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160544">
        <property type="entry name" value="SSF160544"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0966">Cell projection</keyword>
    <keyword evidence="3" id="KW-0969">Cilium</keyword>
    <keyword evidence="3" id="KW-0282">Flagellum</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="32"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="86"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="145"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="187"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="358" mass="39477" checksum="5191F9BD09FA08FF" modified="2019-10-16" version="1">MADQDGEKRFSASESRRQKAREQGQVVRSQDLASAALLLAALAVIGYFGRPMVADVAEVLAKSLADSEVEAFTIESASSLLTQTGYFTLMAVGPIMVCMFICAILVNILQTGPMLLPDKLMPKFSNISPMQGIKRLLALPNFMRLGFGIFKLAVISVVAAICLYHWYEAVLAVSQFGVAAVAKVIFDATFFTCLWIGGALFVLAAFDFAFQWWKHEQDLMMTEQEMRDEMKESQGDPQVIARRRQVQRQLAMQRMQSDVPNSDVIVTNPTELAIAIKYDPQTMAAPIVSAKGAGLLAQKIRRIGLEHGIAIVERKPLAQALYKNVEVGHPVPSEQYQAVAEVLRYVYQLEGRAMPGAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUJ8</accession>
    <name>A0A518IUJ8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">D-beta-hydroxybutyrate dehydrogenase</fullName>
            <ecNumber evidence="1">1.1.1.30</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">bdhA</name>
        <name evidence="1" type="ORF">Mal33_27380</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.1.30" evidence="1"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003858">
        <property type="term" value="F:3-hydroxybutyrate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011294">
        <property type="entry name" value="3-OHbutyrate_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01963">
        <property type="entry name" value="PHB_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="252" mass="26426" checksum="BB28EF349F87211A" modified="2019-10-16" version="1">MKRTVLISGAGSGLGRGLGICLAGQGHTILATDLDLSRAEQTAAEIVAAGGAAQAHQLDVSSEQNVQDLLARVGPIDVLINNAGLQHVAPLEDFPLAKWEQLFDVMVKGTFLMSRAVLPGMRAAGYGRMIHIGSIHSLVASPYKTAYTAAKHAILGFSKVLALETAGSEITSNVICPAYIRTPLVDAQIGDQAIARGITEAEVIDQVMLAPMPKKAFIECDEVAAAIEYLASPLARNVTGQTLTIDGGWTAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUP3</accession>
    <name>A0A518IUP3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Serine protease HtrA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">htrA_2</name>
        <name evidence="3" type="ORF">Mal33_28090</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001940">
        <property type="entry name" value="Peptidase_S1C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13180">
        <property type="entry name" value="PDZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00834">
        <property type="entry name" value="PROTEASES2C"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021740084" evidence="1">
        <location>
            <begin position="24"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="2">
        <location>
            <begin position="258"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="363" mass="38944" checksum="FB81FE01C23254C9" modified="2019-10-16" version="1" precursor="true">MMNFSRSITALAIACGLTSSTFAQLKPASLVNDRPEIDIPAEIAVLQSMSRVVKHVARDAKPCVVHLEARKTETKRGRSEEFDEAGSGAIVVIDGRHYVVTNRHVVFGAKESQVTIRLSDARELHPLKIVSDPSTDVAIMEIRGEDLQAAQLGDSDLVDIGDFVLAIGSPFGLSHSVTFGIISAKGRRDLTLGEERIELQDFFQTDAAINPGNSGGPLLNLRGEVIGLNTAIASSSGGSEGIGFAIPINMVMLVARQLAAVGKLQRSYLGVSLDPDFGPETASRLGVRRPRGALVKKVTPNSPASEAHLQRDDLIQMFNGVEIEDDDHLVNQVGLTPIGQEVAVVLLREGKQYQTTLTVTARP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUS7</accession>
    <name>A0A518IUS7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">3-isopropylmalate dehydratase large subunit</fullName>
            <ecNumber evidence="12">4.2.1.33</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Alpha-IPM isomerase</fullName>
            <shortName evidence="12">IPMI</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Isopropylmalate isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">leuC1</name>
        <name evidence="12" type="synonym">leuC</name>
        <name evidence="14" type="ORF">Mal33_28470</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 12">Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>(2R,3S)-3-isopropylmalate = (2S)-2-isopropylmalate</text>
            <dbReference type="Rhea" id="RHEA:32287"/>
            <dbReference type="ChEBI" id="CHEBI:1178"/>
            <dbReference type="ChEBI" id="CHEBI:35121"/>
            <dbReference type="EC" id="4.2.1.33"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="12">Binds 1 [4Fe-4S] cluster per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 12">Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 2/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Heterodimer of LeuC and LeuD.</text>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.33" evidence="12"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00048">
        <property type="reaction ID" value="UER00071"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003861">
        <property type="term" value="F:3-isopropylmalate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01583">
        <property type="entry name" value="IPMI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.499.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01026">
        <property type="entry name" value="LeuC_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004430">
        <property type="entry name" value="3-IsopropMal_deHydase_lsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015931">
        <property type="entry name" value="Acnase/IPM_dHydase_lsu_aba_1/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001030">
        <property type="entry name" value="Acoase/IPM_deHydtase_lsu_aba"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018136">
        <property type="entry name" value="Aconitase_4Fe-4S_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036008">
        <property type="entry name" value="Aconitase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033941">
        <property type="entry name" value="IPMI_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00330">
        <property type="entry name" value="Aconitase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00415">
        <property type="entry name" value="ACONITASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53732">
        <property type="entry name" value="SSF53732"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00170">
        <property type="entry name" value="leuC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00450">
        <property type="entry name" value="ACONITASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01244">
        <property type="entry name" value="ACONITASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 12" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6 12" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="11 12" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="8 12" id="KW-0408">Iron</keyword>
    <keyword evidence="9 12" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4 12" id="KW-0432">Leucine biosynthesis</keyword>
    <keyword evidence="10 12 14" id="KW-0456">Lyase</keyword>
    <keyword evidence="7 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aconitase" evidence="13">
        <location>
            <begin position="3"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="341"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="401"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="404"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="QDV56846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="463" mass="50292" checksum="94784B2F33768FF5" modified="2019-10-16" version="1">MFEKIWDNHVVHSEPGKQTILYIDLHLVHEVTSPQAFEGLRLAGRKVRQPGRTIATPDHNVPTSDRSLPIADPIARKQIDTLRNNCKEFGVQLFDIDDVRQGIVHVIGPENGFTQPGMTIVCGDSHTATHGAFGSLAFGIGTSEVEHVLATQTLLQYKPKTFELRVEGDLPRGVTAKDTILYLIGKIGTAGGTGYVLEFTGDPIRKFSMEERMTVCNMSIEAGARAGLIAPDELTFEYLRGKPEAPKDFDAAVEKWKQLPSDPGATYDRSEVFQGSDIQPQITWGTNPGQVISVMDRIPSPGDSTDPTEQKSTAQALEYMGLTAGKSLTDVHIDRVFIGSCTNARIEDLRAAAAVAKGHKVSGSVNAMVVPGSGKVKRQAEEEGLDVIFKEAGFDWREAGCSMCLAMNPDKLAPGERCASTSNRNFEGRQGKGGRTHLVSPEMATAAAVAGHFTDVRQWDFKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUX0</accession>
    <name>A0A518IUX0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Pectate lyase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_28890</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021754411" evidence="2">
        <location>
            <begin position="25"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="510" mass="54564" checksum="7BAF390D7950C60A" modified="2019-10-16" version="1" precursor="true">MKLQSTLVFAAVLLTCFLGRSTNADCGAISSEETPPIATQKSVVDQDQQPQATEQSAAGNEGLSESGKASECGVFDKLKAFPNAEGFGAETAGGRGGRVIVVDNLNDSGPGSLREAVESNGPRFVVFSVAGTIELETSLRISNPQITIAGHSAPGGGIALKNSSSNAGPSIVVKASDVIIRYLRVRPGLAAPSTSVDAISILGGKNIVIANNSFSWAVDENVNLWFDATDVTIQHNIISEGIWDGNHTQRGLHSKGLLSGQKNVRVSVHHNLFAHNDDRNPLLTGLGKNEVVNNIIYNYYQAGIIFSIGRGFKANLIGNVFLPGKQHRAHRYPIIVGGQLVDNAIYVKDNLSPRRSKGTEDDWLNVGFNGIIGDEEYNGSLLDQAVRSKTPFPMSTIPVISEPAATLVERLLPTVGATLPKRDAVDIRIVDDVRKGTGVMINDPAEVGGWPTLEPGTVADRDRDGMPDAWELQHGLNPNDPSDAMQDMNGDGYVNLEQYLECLRLQKTSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUX1</accession>
    <name>A0A518IUX1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Type-4 uracil-DNA glycosylase</fullName>
            <ecNumber evidence="3">3.2.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Mal33_28760</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolyzes single-stranded DNA or mismatched double-stranded DNA and polynucleotides, releasing free uracil.</text>
            <dbReference type="EC" id="3.2.2.27"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.27" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004844">
        <property type="term" value="F:uracil DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005273">
        <property type="entry name" value="Ura-DNA_glyco_family4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005122">
        <property type="entry name" value="Uracil-DNA_glycosylase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036895">
        <property type="entry name" value="Uracil-DNA_glycosylase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03167">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00986">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52141">
        <property type="entry name" value="SSF52141"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00758">
        <property type="entry name" value="UDG_fam4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDG" evidence="10">
        <location>
            <begin position="183"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="65"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="80"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QDV56875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="340" mass="35785" checksum="0D98262E13836C27" modified="2019-10-16" version="1">MNEVPSANLNLPDPHEIRVGVGQLLTHLQRVGVEYLPAADPGRAEQWTTTLLASVAQPAPVAAEPSAAVSATPEGLGQPAAAAPPAPAPPVAAPAAPVAAPPAAAPPAAAPPQPAATPPTAAPQAPAPAARPQPAAAVAGPTIYRTASLPIADRQASLDHWGQQVAQCTLCHELACTRKQTVFGAGHAQARVVFFGEAPGADEDREGIPFVGRAGQLLTKIIEATKLSRDEVYIMNTLKCRPPGNRNPLPDELKNCRPFFEAQLEIIQPEYIVCLGLFAAQSLLQSAPSIGRMRGRFHNYHGSKVVVTYHPSYLLRNAKMKGAVWQDMQMMMRAMGTLPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IV72</accession>
    <name>A0A518IV72_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Circadian clock protein KaiC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_29660</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014774">
        <property type="entry name" value="KaiC-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06745">
        <property type="entry name" value="ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATPase" evidence="1">
        <location>
            <begin position="6"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="297" mass="33209" checksum="FD098E7AF1531171" modified="2019-10-16" version="1">MPERLSTGNPALDQMLGGGLLPGTLTVVAGATGIGKTQLGISYLFAGSSQNEPQGAMLDLSARGDSQNHAGYAQRLFDADWRSVAPDTMPSGSGNEWVFDSEVRMPNSLNMLGYSGRRVVRDQMDPDQWNEWQRQLNRSLNKMIGFLYGHLVRGTRRFVIDGIEPSDRPEDSLQMELFEYAYHRVMRQEHDWVARDLLRQDFRYFADQVTAHAYSNSEAACLLLCTTPESMLDQLIDRPLANGDLGALANTLIYMGKIRDGLQMRRGLYIAKHRGSQCDDNVRLFEIDEAGLQLSAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IV91</accession>
    <name>A0A518IV91_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Acetyltransf_6 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_30120</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038740">
        <property type="entry name" value="BioF2-like_GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13480">
        <property type="entry name" value="Acetyltransf_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acetyltransf_6" evidence="1">
        <location>
            <begin position="170"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="365" mass="41669" checksum="D7E804541EE9971E" modified="2019-10-16" version="1">MNLRIVKSEAEFMQLQEAWDALDPAPMQSFAWNFAWWQSFSRYNALRIYCYEDQGTVVGIAPFYFDRRLGQRALKFLGSGITCSDYAQLIVADEHRQDFLSEIAEDVRQSRFIRMVELDGVLADPSQNPDLKIVDQLGTPFWRYDRDVDSSWILELPDSWDQFLKQSASNLRRKVRKAARRIDGGEVQIRSTRDDLPVESAFATLVRLHLERTDAKGLQSAFCDPEYVRFLHAAAADLIPQGKAEILTAEYQGKPIAVHFNLQGPRGPQLYQSGASRDAMELEPGYLLFTHVIRRTIGEGIAEFDFLRGDEPYKKFWGARPVPLATVRCVSKSLFTTAGHKLALGARRLKNDLRSFQWRGLGVAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVA6</accession>
    <name>A0A518IVA6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4430 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_30220</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027954">
        <property type="entry name" value="DUF4430"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14478">
        <property type="entry name" value="DUF4430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021803870" description="DUF4430 domain-containing protein" evidence="1">
        <location>
            <begin position="33"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4430" evidence="2">
        <location>
            <begin position="70"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="147" mass="15648" checksum="CC86C9B566808E0D" modified="2019-10-16" version="1" precursor="true">MFVCQTVSVASLQRIAGIGCLLLLALVGCQNATEPAAAPPADGPKIAVRFVFEFGEGEPVEVALDAVPTGSTVADAMRQIAEMPDTVQLEIVGKGDMTFVQSINGKTTSGNEGWSYYVNEEWAQEGVGAIELEDGDLVRWTYGESEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVS4</accession>
    <name>A0A518IVS4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Penicillinase repressor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">blaI</name>
        <name evidence="2" type="ORF">Mal33_31900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the BlaI transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005650">
        <property type="entry name" value="BlaI_family"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34134">
        <property type="entry name" value="PTHR34134"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03965">
        <property type="entry name" value="Penicillinase_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF019455">
        <property type="entry name" value="CopR_AtkY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="111" mass="12621" checksum="E3932CD7403FD284" modified="2019-10-16" version="1">MNVIWGNEPTGIPDIVAQMPRELAYSTVMTTVRILCDKGFVRQCGKEGRAFIYESCVGRDEVRCSMVRDLAERLFGGSVKSMVMNMIQEETIDAQDLKDVKKMIRDLEARQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IW25</accession>
    <name>A0A518IW25_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">30S ribosomal protein S10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 6" type="primary">rpsJ</name>
        <name evidence="6" type="ORF">Mal33_32920</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Involved in the binding of tRNA to the ribosomes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 30S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS10 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.600">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00508">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001848">
        <property type="entry name" value="Ribosomal_S10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027486">
        <property type="entry name" value="Ribosomal_S10_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036838">
        <property type="entry name" value="Ribosomal_S10_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11700">
        <property type="entry name" value="PTHR11700"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00338">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00971">
        <property type="entry name" value="RIBOSOMALS10"/>
    </dbReference>
    <dbReference type="SMART" id="SM01403">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54999">
        <property type="entry name" value="SSF54999"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01049">
        <property type="entry name" value="rpsJ_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal_S10" evidence="5">
        <location>
            <begin position="9"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV57288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="107" mass="11979" checksum="E56D1A0E21A56B3E" modified="2019-10-16" version="1">MASPHEIIRIRMEAYDHSILDQSAADIVDTVKRTHSEVHGPIPLPTRIERYTVISGPFVNKKARQQFEIRTHKRLIDIVQATAKTIEALNKLSLPAGVDIKIKATAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IW74</accession>
    <name>A0A518IW74_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">RNA polymerase principal sigma factor HrdB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">hrdB</name>
        <name evidence="6" type="ORF">Mal33_33480</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000943">
        <property type="entry name" value="RNA_pol_sigma70"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007630">
        <property type="entry name" value="RNA_pol_sigma70_r4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04545">
        <property type="entry name" value="Sigma70_r4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00046">
        <property type="entry name" value="SIGMA70FCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00716">
        <property type="entry name" value="SIGMA70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="RNA_pol_sigma70" evidence="5">
        <location>
            <begin position="514"/>
            <end position="540"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV57344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="553" mass="64511" checksum="F1F04B838D6790F8" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IW93</accession>
    <name>A0A518IW93_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NAD(P)H-hydrate epimerase</fullName>
            <ecNumber evidence="1">5.1.99.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">NAD(P)HX epimerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">nnr_2</name>
        <name evidence="1" type="synonym">nnrE</name>
        <name evidence="3" type="ORF">Mal33_33660</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(6R)-NADHX = (6S)-NADHX</text>
            <dbReference type="Rhea" id="RHEA:32215"/>
            <dbReference type="ChEBI" id="CHEBI:64074"/>
            <dbReference type="ChEBI" id="CHEBI:64075"/>
            <dbReference type="EC" id="5.1.99.6"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(6R)-NADPHX = (6S)-NADPHX</text>
            <dbReference type="Rhea" id="RHEA:32227"/>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
            <dbReference type="ChEBI" id="CHEBI:64077"/>
            <dbReference type="EC" id="5.1.99.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
        <text evidence="1">Binds 1 potassium ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the NnrE/AIBP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="5.1.99.6" evidence="1"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052856">
        <property type="term" value="F:NADHX epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052857">
        <property type="term" value="F:NADPHX epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01966">
        <property type="entry name" value="NADHX_epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004443">
        <property type="entry name" value="YjeF_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036652">
        <property type="entry name" value="YjeF_N_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03853">
        <property type="entry name" value="YjeF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64153">
        <property type="entry name" value="SSF64153"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00197">
        <property type="entry name" value="yjeF_nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51385">
        <property type="entry name" value="YJEF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0413">Isomerase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0520">NAD</keyword>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1" id="KW-0630">Potassium</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YjeF N-terminal" evidence="2">
        <location>
            <begin position="16"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="NADPHX" evidence="1">
        <location>
            <begin position="63"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="NADPHX" evidence="1">
        <location>
            <begin position="138"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="230" mass="23896" checksum="3AF0915171E30AB3" modified="2019-10-16" version="1">MTQPMNPTTPLSREQVRAIDEIAIGEFSMPGICLMENAGRGAAEQIAAFTAATEIAILCGGGNNGGDGFVIARHLQLMGRKPHIFLLADPARLSGDALTNWQIAMASKLPCEVVDEHSLPSLQRKLAEASCIVDAMLGTGASGDPRGTIANAIRNANATSAVRVAIDLPSGLDCDTGSPGDPCFRADLTCTFVAEKIGFAAAEASEFTGAVRVVSIGAPAELLRRYAVAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IW98</accession>
    <name>A0A518IW98_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_33680</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="450" mass="49492" checksum="884CED3054D27A53" modified="2019-10-16" version="1">MNAAESQPLQRLAQADALHLPGGRFTLGLPDASRHAAAAGIGDSICWIPDSVCLRLPLYAVISSRIGRHLHRRCDWFALLRQAIAATQQDGATLLISEGTAAAPWAQRAADRFACPAITICVSPDNEDFDRWLSRIQKHPPGDRIAISPPIAPSTAIADAPRRDAVAIFLADRVYAPLVSSGGNIDRLLDRRLADRRWNPASVWIAIDPKNRAAQSLIDRGAVSWMLSAGNDPVAVTPAEVPRDEDLSLGELLSQRGESDAADRWPYLVHCTRERDGAWPDQSEADFHDELLSGDCNCESGPLATLRRILQTGRLLATDRLTRGSQSVVCFSARPLADLLDGRVFRSHLGRWDYEPYGIAIHRSLLETQGSRPAIYGDADDFAALAPADRAFFQDRGTTHDWRREKEWRVAADIDLTTIASHEAFVFVRSVNDLAPIAPYCRWPIVVVGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWC0</accession>
    <name>A0A518IWC0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L7/L12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 8" type="primary">rplL</name>
        <name evidence="8" type="ORF">Mal33_33820</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the bacterial ribosomal protein bL12 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00387">
        <property type="entry name" value="Ribosomal_L7_L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00368">
        <property type="entry name" value="Ribosomal_L7_L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000206">
        <property type="entry name" value="Ribosomal_L7/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014719">
        <property type="entry name" value="Ribosomal_L7/12_C/ClpS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013823">
        <property type="entry name" value="Ribosomal_L7/L12_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008932">
        <property type="entry name" value="Ribosomal_L7/L12_oligo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036235">
        <property type="entry name" value="Ribosomal_L7/L12_oligo_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45987">
        <property type="entry name" value="PTHR45987"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00542">
        <property type="entry name" value="Ribosomal_L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16320">
        <property type="entry name" value="Ribosomal_L12_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48300">
        <property type="entry name" value="SSF48300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54736">
        <property type="entry name" value="SSF54736"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00855">
        <property type="entry name" value="L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 8" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal_L12_N" evidence="7">
        <location>
            <begin position="15"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal_L12" evidence="6">
        <location>
            <begin position="69"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="115"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF16320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV57377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="135" mass="14144" checksum="430358E1C6A56B40" modified="2019-10-16" version="1">MSEDTAVAEVSAETKEMGDKIAQLTLKQAKELSDYLKDEHGIEPASGGGAVMMAAPTDGPAAEAEKTEFDVVLTGFGDKKLNVVKVVKNLTGASLMDAKKMVESCPATLKEAVSKEDAEKVKAEVEEAGGSVELK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWR8</accession>
    <name>A0A518IWR8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Outer membrane biogenesis protein BamB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_35480</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018391">
        <property type="entry name" value="PQQ_beta_propeller_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002372">
        <property type="entry name" value="PQQ_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13360">
        <property type="entry name" value="PQQ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00564">
        <property type="entry name" value="PQQ"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="367" mass="40301" checksum="5692326EF1BAB329" modified="2019-10-16" version="1">MKADNFKRHLIPPMNGPTMLRQTLLTATLLLFPLDTSADDWPQFLGPQGAARSSDAVATSWNETENMAWRVDLPGSGSSSPIITGNRVILTCYVNGDGNAKRQVLCFDKNSGEQLWSVDFPIDYREDGYQGYITEHGYASNTPVTDGENVYVFLGKGGVHSIGLDGQRNWSVDVGKESSNRRWGSAASLLLFENSVIVNAAEESKAIIALDKATGKELWRQEAGMLELTYGTPRIVLLADGESELVISVPEEMWAMNPRTGKLKWYAQTPMTGNVTPSVIVAGETIYSFGGYRASGCIAVKAGGKDDVSDSNVLWTNQSSSYVATPLLHHGRFYWIDDRGIAYCTSADRAIQCLNLWDLLRSILRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWS3</accession>
    <name>A0A518IWS3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">RNA polymerase sigma factor SigL</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_35430</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011517">
        <property type="entry name" value="RNA_pol_sigma70_ECF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07638">
        <property type="entry name" value="Sigma70_ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02999">
        <property type="entry name" value="Sig-70_X6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="189" mass="21380" checksum="43AF7D94624B09AB" modified="2019-10-16" version="1">MNIVKRDVTKILSAIHDGDRQAASELLPLVYEELRKLAASKMNQEKSGQTLQPTALVHEAFLRLVGGETPQEWDSRGHFFAAAAEAMRRILIDNARRRGRNKRGGDYVRQELHEESAFVDADDVDDLLALDDALNKLALEDADLAKLVELRYFTGLTIEETAQVLGQSSRTIKRHWAFARAWLQREINA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWS9</accession>
    <name>A0A518IWS9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">pknB_16</name>
        <name evidence="10" type="ORF">Mal33_35470</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
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        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="408"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="86"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="434"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="116"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV57537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="739" mass="82311" checksum="3AC9BA7DDE1E213F" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWU6</accession>
    <name>A0A518IWU6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transcriptional regulatory protein ZraR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">zraR_7</name>
        <name evidence="8" type="ORF">Mal33_35710</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
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        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
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    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
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        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
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        <property type="entry name" value="HTH_Fis"/>
    </dbReference>
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        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR025662">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025944">
        <property type="entry name" value="Sigma_54_int_dom_CS"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01590">
        <property type="entry name" value="HTHFIS"/>
    </dbReference>
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        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SIGMA54_INTERACT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="SIGMA54_INTERACT_4"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Response regulatory" evidence="7">
        <location>
            <begin position="12"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma-54 factor interaction" evidence="6">
        <location>
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            <end position="373"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="5">
        <location>
            <position position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV57561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="453" mass="49307" checksum="A244770698AF8C07" modified="2019-10-16" version="1">MNSIPHALRSTHVLLVDTDSNHCSEVTDQLSQRQFHVSTVASATEAIQLTSNQRCDAAVLFCDELEPQVLDDLRHLQSAHASLQVIVVSTTTSITAAVEAMKAGACDFLTKPISPNALALAIQTAGTNRPRCTHTACSQPAVVREKKNKTSILGKSAAIDSVLQWIARVAPSEMPVLIEGESGTGKELVAREIHAASNVADQALVTINCAAVPASLLESELFGHEKGSFTGAIATKRGLFETADGGTLFIDEFGELAGDLQAKLLRVIEDGRLRRVGSTEERQVNVRLIAATNKTLIDEVRSGRFREDLFYRVNVLGARLPSLRERTEDIGLLAQHFLGEGWVLGDGVLELLQRYTWPGNVRQLSNVMERCKVLAGQPGIIAIDDLPSEIVDASDQQQLEIGGNVDLHTLNRSHVLKVLKQNRGNKAKSARVLGINRRSLYRLLEKYNAKHSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IX05</accession>
    <name>A0A518IX05_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_36180</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008391">
        <property type="entry name" value="AXE1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05448">
        <property type="entry name" value="AXE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AXE1" evidence="1">
        <location>
            <begin position="117"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="695" mass="78301" checksum="B91884F8EEEE2734" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXE0</accession>
    <name>A0A518IXE0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_37610</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010869">
        <property type="entry name" value="DUF1501"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07394">
        <property type="entry name" value="DUF1501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="489" mass="54288" checksum="DDAB6436F84CFF18" modified="2019-10-16" version="1">MAANKSQFDSQMNDPHNRRRFLSGAGLGLGSIALSSMLADERRANAAGLHLPDGRPHFAPKAKNVIWLFMRGGVSHMESFDPKPMLNKFAGKSIDETPYANVSDPELLKRVRVVVVNDANGQQRKQLYPLQVGYKAYGQSGIEVSDWFPHIGSCIDDIAVVRSMWTTDDNHGAQVQFHSGRHMLDPRVPTIGAWINYGLGTLNQNLPQFISMGPRFFDRRDGHYLGPAYDAVELKVDPSNPLDYASPQRAVTPTEQQMGFDLVSQLNRLSDSRYPRDAAMEARTKSYELAFRMQTAVPDVIRFDQETQATKNLYGLDQPETRAFGEQLLAARRFSEQGVRFIQIMHGGGAAGAWDQHSNLKAKHSQLSMQVDRPIAGLLKDLKQRGMLDETLVVFATEFGRTPGSQGSDGRDHHPYGFSVWMAGGGIKGGVAHGATDEIGFHATENPHYVTDIHATIMHQLGLDSHRMEVAGHKRLEQDFGHVIHDILA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXE3</accession>
    <name>A0A518IXE3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Heat shock protein HtpX</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Mal33_37710</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the peptidase M48 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001915">
        <property type="entry name" value="Peptidase_M48"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01435">
        <property type="entry name" value="Peptidase_M48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1 6" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0346">Stress response</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="42"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M48" evidence="9">
        <location>
            <begin position="97"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV57757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="270" mass="29381" checksum="5CB0E454F792B11E" modified="2019-10-16" version="1">MASTFDDPISSPTRSPGTFAAPRVKPKEHVARGTGFHAMVGWILFGIVGPILVLLTIVGTYGIALIAWLIALVKYNQRAKKAEAVLMGNGVKVAPDQFPAIYESVARMAGQLELKTLPDVYIIESNQQNAFALKIGSKQNIVLIDDIVYGALDNNNPEILDFIIGHELAHHALGHTGLFRGMISSHYKTLSRLDEFSCDAVSVAMQQNPQPGLDAMTLLAVGPRLYPRVDKASFAKQAQQVVSNKYSKKAESAMSHPLLLRRYGAIEAKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXH4</accession>
    <name>A0A518IXH4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FecR protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_38060</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006860">
        <property type="entry name" value="FecR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012373">
        <property type="entry name" value="Ferrdict_sens_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30273">
        <property type="entry name" value="PTHR30273"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04773">
        <property type="entry name" value="FecR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="FecR" evidence="2">
        <location>
            <begin position="200"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="545" mass="58797" checksum="46A6AD5E8D26BEC1" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXN7</accession>
    <name>A0A518IXN7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Arylsulfatase</fullName>
            <ecNumber evidence="6">3.1.6.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">atsA_28</name>
        <name evidence="6" type="ORF">Mal33_38640</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="PTM">
        <text evidence="3">The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the sulfatase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.6.1" evidence="6"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004065">
        <property type="term" value="F:arylsulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024607">
        <property type="entry name" value="Sulfatase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00523">
        <property type="entry name" value="SULFATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00149">
        <property type="entry name" value="SULFATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sulfatase" evidence="5">
        <location>
            <begin position="37"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="490"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="modified residue" description="3-oxoalanine (Cys)" evidence="3">
        <location>
            <position position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR600917-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV57849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="515" mass="57160" checksum="6501545420DF8559" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXW9</accession>
    <name>A0A518IXW9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Macrolide export ATP-binding/permease protein MacB</fullName>
            <ecNumber evidence="9">3.6.3.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">macB_7</name>
        <name evidence="9" type="ORF">Mal33_39470</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="3.6.3.-" evidence="9"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="248"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="293"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="340"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="8">
        <location>
            <begin position="18"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="7">
        <location>
            <begin position="279"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV57931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="375" mass="40275" checksum="8EA2A5798478AC0F" modified="2019-10-16" version="1">MRFGSLIFRNVLRRKLRSSLTIFAVAIAVGSVVSLVGIANGFKETFMEFYQGVDIDMVVVRSGSQRRLTSTLDESLAQRIAALQGVKEAVGGLADVVSFPDVNLYVVPVSGLPTDTTVFDHFHVLDGQRIENGEKPQVMLGTTLADTLEKKVGESLEVVEEEPFEIVAIFESDNVLENGSMIISLPQLQRIMGREGQISGVSIVLEDGVTDQQKESITEAIHKMDTGLSVRTTRDHVESLSEIQVAVAMAWLTSTVAILIGSLGTLNTMFMSIQERTPEIGILKAIGWERHRIISMILGESILLSLMGGVVGTIAATLLVKLLTQMPAVNGLIQGKISPAILMQAFAVAAVVGLLGGLLPAISASRLAPTVALRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYG3</accession>
    <name>A0A518IYG3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/beta hydrolase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_41390</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004308">
        <property type="term" value="F:exo-alpha-sialidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026856">
        <property type="entry name" value="Sialidase_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10628">
        <property type="entry name" value="PTHR10628"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021839351" evidence="1">
        <location>
            <begin position="19"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S9" evidence="2">
        <location>
            <begin position="201"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="372" mass="42484" checksum="D88207022E143797" modified="2019-10-16" version="1" precursor="true">MKPWIPLFLIALSANSLAAEERQPPASIARYFTPPTQWQNDLGSFRSPLEFNDGTLVENQTDWKRRRAEIYQQWQDLMGQWPALIEDQDFEVLGSERRENFVQHKVRFRWLPEESTEGYLLIPDGEGERPAVITVFYEPETAIGKGREGRDFALQLARRGFVVLSIGTTDATAAKTYGLYYPSLNDAQVQPLSMLGYAAANAWHALARRPEVDSDRIGIVGHSFGGKWAMFASCLFDRFACAAWSDPGIVFDNARNSVNYWEPWYLGYHPRPWRKRGLITDSNPAHGLYPKLMQQGRDLHELHALMAPRPFLVSGGSEDPPQRWQALNHTIAVNRLLGYENRVAMTNRPEHSPNAESNAVIYAFFEHFLMNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYI1</accession>
    <name>A0A518IYI1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_41590</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="61" mass="7001" checksum="E9DD510527EF2A40" modified="2019-10-16" version="1">MSSAKEAMIDIIGRQPEDSTYDEILRELAFARMVQRGLDDSDAGRTVTDDEIKRRIDSRQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYW0</accession>
    <name>A0A518IYW0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_42900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="96" mass="9137" checksum="5B66173E7E96BE65" modified="2019-10-16" version="1">MQFLPLIIQLVTGAVGGNLTGSLFKKLDLGLIGNSIAGILGGGLGGQLLGMLGIAAAPGGSLDIGTVLGSIASGGVGGGVLMVIVGLIKSVLLKGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ34</accession>
    <name>A0A518IZ34_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_43570</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="233"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="275"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="316"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="348"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="370" mass="41601" checksum="C61D1A795EEF9A44" modified="2019-10-16" version="1">MLRFVMLCLMFGFAHPVIGIEPSREPTAELEPEPAWSVANRPDHFRKKRSFASPGAIEAWSDRVDRVEEGFLFIDGKHIPCPLEIKTDPETGQLHANGIPLWFDDDIGQPRYRRANAEPSRQPRNSQWVQRRLVQSLEGKRVVLAFGQRPAQFVDEVDFFPSLLNPDPTSQPFTDMRDSILDPELQMMVEQWLVSYSPSAELVEAAQVIVDRYDKVASENNAQIAATTTLSRLTYPMTMFGLIVGVYTFGHLMMTTPKSPALYPNANLLEMMSQATVVSVVLICAHAALDLTWTLLTSQAGQMREINPFGAQFLENPRALVAFKAIATLGACGLLIGLRKHRAAQTACWWMCLVCTILTFRWLIFSSMLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZC8</accession>
    <name>A0A518IZC8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative inner membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Mal33_44690</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002549">
        <property type="entry name" value="AI-2E-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21716">
        <property type="entry name" value="PTHR21716"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01594">
        <property type="entry name" value="AI-2E_transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="31"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="59"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="159"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="216"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="244"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="325"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV58446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="367" mass="40123" checksum="80E82169221D7C80" modified="2019-10-16" version="1">MPRHFSFWLLVGLIGLFGLLFFHVIKPFVLAIFVAIVLTVLFAPLHQALTGFMSGHNRIAAGVTTGLVMVVVLLPIGVTLLMAGNQVTQIGRDAVGWFDGRSDDAFDETIEKLGKSTVGSAMNQVYRKLDPPQRQQIQESVSRISDGFTAELYDKTRGLISNIVTFGVGLCIMALSFYYFLADRELFIRELHRMMPLENEEEQRLFDKFQRVCRGVVLGTVVAGVVQAALAGLAFAVLGVPNVWVLMVLTMFCSFIPFLGSAAVWASVAAWLMIEGNYGSAIGLAIYGAALISTSDNLVRAYVIGNQAKLHPLVALVTVLGALKLMGLWGIFVGPMIAAFFYALLNIARERVVRQNQQQHVAAPPET</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZH4</accession>
    <name>A0A518IZH4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Quinoprotein glucose dehydrogenase B</fullName>
            <ecNumber evidence="7">1.1.5.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">gdhB_2</name>
        <name evidence="7" type="ORF">Mal33_44580</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.5.2" evidence="7"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008876">
        <property type="term" value="F:quinoprotein glucose dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012938">
        <property type="entry name" value="Glc/Sorbosone_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013427">
        <property type="entry name" value="Haem-bd_dom_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013428">
        <property type="entry name" value="Membrane-bound_put_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011041">
        <property type="entry name" value="Quinoprot_gluc/sorb_DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00034">
        <property type="entry name" value="Cytochrom_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07995">
        <property type="entry name" value="GSDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50952">
        <property type="entry name" value="SSF50952"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02603">
        <property type="entry name" value="CxxCH_TIGR02603"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02604">
        <property type="entry name" value="Piru_Ver_Nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021840648" evidence="5">
        <location>
            <begin position="20"/>
            <end position="1111"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="6">
        <location>
            <begin position="963"/>
            <end position="1100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV58435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1111" mass="121751" checksum="EDFD76415E2E3452" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZI2</accession>
    <name>A0A518IZI2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Polysaccharide biosynthesis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_45120</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="134"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="167"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="204"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="288"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="319"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="353"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="379"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="419" mass="45669" checksum="D93995FF83482896" modified="2019-10-16" version="1">MVALNVVGIFLGYGATIILARELSRVAFDQYIGAIATLGLFASLAEGGFGKYGLRVIPIYNEAQDGGRIAGYLRFAFLGTLLLSLLLAIAMIVLAAPLHSGNRRDVVTLAFVYLPSMAGAGVVIDLLLAFRMPIVAMVISRIMIPATTLLLILMLTQTMHFNASHAVLCFASGSVMALLLGMLLCYRQASPLVGDAEVETNVRGWISESVTFMFFTFMVSWLFRSTLVITHHMPHGDIGVGLLAPAFETGGLILLLSKSTDKFFQPAVSLYMEENNWRQMSILRRDRALMVGAGIILFLLVVAFFGKTILGIYGPDFVASYPALCWVAVGSSMTTLFSLAPTFLLYAGRRRMLTWLLGLHAGLLLVLTVIFYWKFGGTGAAAAYAVCVTSYSLSNLYFANREFQKLKSELRETDAVAID</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZV0</accession>
    <name>A0A518IZV0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glycogen synthase</fullName>
            <ecNumber evidence="7">2.4.1.21</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Starch [bacterial glycogen] synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 10" type="primary">glgA</name>
        <name evidence="10" type="ORF">Mal33_45880</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 7">Synthesizes alpha-1,4-glucan chains using ADP-glucose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>[(1-&gt;4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1-&gt;4)-alpha-D-glucosyl](n+1) + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18189"/>
            <dbReference type="Rhea" id="RHEA-COMP:9584"/>
            <dbReference type="Rhea" id="RHEA-COMP:9587"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15444"/>
            <dbReference type="ChEBI" id="CHEBI:57498"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.4.1.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Glycan biosynthesis; glycogen biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.21" evidence="7"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00164"/>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033201">
        <property type="term" value="F:alpha-1,4-glucan synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004373">
        <property type="term" value="F:glycogen (starch) synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009011">
        <property type="term" value="F:starch synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005978">
        <property type="term" value="P:glycogen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00484">
        <property type="entry name" value="Glycogen_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011835">
        <property type="entry name" value="GS/SS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013534">
        <property type="entry name" value="Starch_synth_cat_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08323">
        <property type="entry name" value="Glyco_transf_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02095">
        <property type="entry name" value="glgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0320">Glycogen biosynthesis</keyword>
    <keyword evidence="4 7 10" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_transf_5" evidence="9">
        <location>
            <begin position="11"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="8">
        <location>
            <begin position="309"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="24"/>
        </location>
        <ligand>
            <name>ADP-alpha-D-glucose</name>
            <dbReference type="ChEBI" id="CHEBI:57498"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV58565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="506" mass="56745" checksum="6FACE71F71E9CE28" modified="2019-10-16" version="1">MTAPVDSSPLNIVILTTEAVPFAKTGGLADVCGSLPQQLAQRGHKVTVIMPAFRQVFSAGQTIEPTEHNVSVAIAGKTVNARLLKSHLPGDQCEVLLIDQPSYYDREQLYGDAQGDFWDNCERFTFFCRAALSAIDTLDSPPDVVHCNDWQTGLIPAYIANRFESHPWMDHVATIMTIHNMAYQGQFWHWDMLLNGLGWDQFTPDKMEFYGHLNLLKTGLVFADSITTVSQRYAEEIQQPEFGCGLDGVLRNRHQVLSGIVNGVDYQIWDPATDEHLDAHYGIDDWKAGKRANRSALRQEMGLEDNPEIPLIGLIGRLADQKGWDLVTEMMNNWLGEGSPVQWVVLGTGDHRYHQTLSDLASRYSKRLAVHLGFSDRLAHRIEAASDMFLMPSRYEPCGLNQLYSLRYGTVPIVNPTGGLSDTVTDANEETVRLQTATGFHMSHYNARSLGETLDRAVTTYRENPGVWDQIVATGMQQDWSWQQSATRYEQIYLETIDRLHGAAVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZY0</accession>
    <name>A0A518IZY0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Arsenate reductase</fullName>
            <ecNumber evidence="3">1.20.4.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">arsC_2</name>
        <name evidence="3" type="ORF">Mal33_46640</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the ArsC family.</text>
    </comment>
    <dbReference type="EC" id="1.20.4.1" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008794">
        <property type="term" value="F:arsenate reductase (glutaredoxin) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd03034">
        <property type="entry name" value="ArsC_ArsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006659">
        <property type="entry name" value="Arsenate_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006660">
        <property type="entry name" value="Arsenate_reductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30041">
        <property type="entry name" value="PTHR30041"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03960">
        <property type="entry name" value="ArsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00014">
        <property type="entry name" value="arsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51353">
        <property type="entry name" value="ARSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="160" mass="17852" checksum="E34CF318EA04DE2C" modified="2019-10-16" version="1">MLLLFTGFDPIGRRDRILAVPRADAARCLAEYRTASTFFQLPKSMTTIYHNPRCSKSRAAVELLESRQIEHTVVKYLETPPTEKELKEIVAMLGIEPQQLVRRGEALFKELGLGEKQLSHDEWLAVLAANPKLIERPIVVHGGRAAIGRPIDNVAALLDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J030</accession>
    <name>A0A518J030_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_47280</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="52" mass="6021" checksum="6A87116C9ADA5992" modified="2019-10-16" version="1">MVCSVQIIQALSKVKHAKRQRLARTRLSIHTSRLVVFADCVLVKRLLDFQPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J040</accession>
    <name>A0A518J040_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Regulatory protein RepA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">repA</name>
        <name evidence="2" type="ORF">Mal33_47350</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="430"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="503"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="430"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="523" mass="59045" checksum="BC6B8EF5179B752D" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J063</accession>
    <name>A0A518J063_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF547 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_47560</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006869">
        <property type="entry name" value="DUF547"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04784">
        <property type="entry name" value="DUF547"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF547" evidence="2">
        <location>
            <begin position="92"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="278"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="300" mass="33611" checksum="B898D824E040D010" modified="2019-10-16" version="1">MNKSKASYYGPFFWLAIVSFSVPIVVAAKAFQEVQLSTKPTPHPDASGVDHALWDYLLKTHVENGLVDYDGIARDHLFRTYLRQLSESEPSKLTTSADQLALFCNAYNAFVINGVITHKIRDSVMNYNVEGTEFFDLKEHILYGETFSLNEIEHELIRKRFREPRIHVALVCAAKSCPAIRAEAYTGPRLTKQFEDQSIQFANQTKYVTYDAASDTLRLSPLLDWYGGDWDPVGGYLPWLADRLEDDAIKQAILRASRNETSVAFLDYDWSLNSQAAAGSAAPKPASKKGQFGSGSIPNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J070</accession>
    <name>A0A518J070_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_47570</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
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            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="54" mass="5880" checksum="F575DCE3D39143E2" modified="2019-10-16" version="1">MIKDQACPMVAACSVNVAWAETLCRAWFAGQAPAKLATQPEMNSFPFAALNEMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0H4</accession>
    <name>A0A518J0H4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_48570</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011487">
        <property type="entry name" value="DUF1598"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07643">
        <property type="entry name" value="DUF1598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022161399" evidence="1">
        <location>
            <begin position="30"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="456" mass="49436" checksum="149203C2F153897A" modified="2019-10-16" version="1" precursor="true">MKCPQGLQVRVRSAICIASMLVIAAPSFAGQVGFQQNSVGGVMVDAGGVVRAATPDEQQQLLRTVRAQVRVAAGELAKPAEMRMISLKGLQKAIATALANGTDLPEEIRYLAGLQRVQYVFAYPEQNDIVIAGPAEPWIVRDDAAVVGAISGQPMMLIDDLVTAMQSVEAARRSGISCSIEPTAEGHQRLNRLLSKVQLRNGQNPKALEPQMKQAFGPQMVKINGVPTDSHYARILVAADYQMKRIAMGLEPSRLPNLPSYLQMARGSLTQSNANPRWWMACDYNSLSHSEDKLSWKLSGRGVKTMTENDLIGADGQVVGNAKADPKAQQWADLMTENYSELSQQFPVFGQLRNMIDLSVVATLIVQERLDETAGINLDLLMGRGTEVPVAVYTAPAAISPECSFLRSRKGWIVTTSGGVDINAFEIVERQAADATLSGVRGKSAAEEATSWWWNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J110</accession>
    <name>A0A518J110_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_50560</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="67" mass="7704" checksum="4D11592EEA8FC358" modified="2019-10-16" version="1">MIVKLQLLNSPIGHSEFNPAARESQLSVRRYVIIRKWNHIVIGEYQVNLAHITSPSVLDSFVLFDNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J115</accession>
    <name>A0A518J115_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_50550</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="130" mass="14877" checksum="866A969B2150A1EA" modified="2019-10-16" version="1">MPDPDPFPKVKRAIIKALSEFVIPLGFQQYRKSVYFIRDRGPIRDMFFVQKMRSNAVSIAYGVTAKPDDDDEWTPGIPNARWLNRQEFYRCKYVEHVAGSIGRATADFESEALPWFAAIETEGDLAKTTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J156</accession>
    <name>A0A518J156_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_50980</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="54" mass="5906" checksum="EF7B093FA04DEA16" modified="2019-10-16" version="1">MQNDSDERPQKQDPVKASVPACPVCGGRLIDIRGKLQCTVCHRICETCCEGGRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J168</accession>
    <name>A0A518J168_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Choline-sulfatase</fullName>
            <ecNumber evidence="5">3.1.6.6</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">betC_9</name>
        <name evidence="5" type="ORF">Mal33_51030</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="PTM">
        <text evidence="3">The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the sulfatase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.6.6" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047753">
        <property type="term" value="F:choline-sulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024607">
        <property type="entry name" value="Sulfatase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00523">
        <property type="entry name" value="SULFATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sulfatase" evidence="4">
        <location>
            <begin position="95"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="modified residue" description="3-oxoalanine (Cys)" evidence="3">
        <location>
            <position position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR600917-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV59078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="546" mass="61493" checksum="984E8C9346AC5372" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1C8</accession>
    <name>A0A518J1C8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Haloalkane dehalogenase</fullName>
            <ecNumber evidence="2">3.8.1.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">dhaA_2</name>
        <name evidence="2" type="ORF">Mal33_51810</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.8.1.5" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018786">
        <property type="term" value="F:haloalkane dehalogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="35"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="283" mass="31835" checksum="9899A8714D18DAED" modified="2019-10-16" version="1">MDFQTFRQRQKNITIDGIIDEPVTVAYTDVGVGEPLLLLHGIPTWSFLFHEIIDPLSQRYRVIAPDLIGYGYSDHRDRFDRSIEVQADMIERFLDKLGIPAAHFVAHDIGGGVALILADRSPDLVRTMVLSNSVAYDSWPIDEMLQLGHPRNAKMDPEDVKQLMEEALDVGLSRPDRSTDEFRTGIAKPYLEPDGIVSLVRNAASLNTNHTTKLTDRINRLTQPTLLLWGVDDQWQPVSTAEQLVKDMPNAKLHAVENCSHWVPQDAPEEFTGAVLEFLDQVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1J2</accession>
    <name>A0A518J1J2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_52440</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022138943" evidence="1">
        <location>
            <begin position="21"/>
            <end position="585"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="585" mass="65226" checksum="38789C4527EB23CE" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1L3</accession>
    <name>A0A518J1L3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_52640</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025489">
        <property type="entry name" value="DUF4381"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14316">
        <property type="entry name" value="DUF4381"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="161" mass="18011" checksum="6E74493AACD15FC1" modified="2019-10-16" version="1">MDDATSLDRLHDIVVPPEVPWWPPAPGWYAVMILVAAGVLAIAYRAWRHWQANRYRRAALQELQSADSAAAISEILRRTALAIQPRAEIADLVGDRWAAWLSEAAPQPMPPQVREQLASAIYRKSEATDELNSLREYASGWIQTHEIPAATNPLPEDRHGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1N0</accession>
    <name>A0A518J1N0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Serine/threonine-protein phosphatase CPPED1</fullName>
            <ecNumber evidence="3">3.1.3.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Calcineurin-like phosphoesterase domain-containing protein 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Mal33_52670</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the metallophosphoesterase superfamily. CPPED1 family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017018">
        <property type="term" value="F:myosin phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07395">
        <property type="entry name" value="MPP_CSTP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041867">
        <property type="entry name" value="MPP_CSTP1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022092152" description="Serine/threonine-protein phosphatase CPPED1" evidence="6">
        <location>
            <begin position="22"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="domain" description="Metallophos" evidence="7">
        <location>
            <begin position="57"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00032900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV59239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="321" mass="36642" checksum="2A32018010B42D5C" modified="2019-10-16" version="1" precursor="true">MQHFLRLSVLVCIATSGFCTAEEPADKPNDRFQQAADRTFKAFDREEEQAWQRPFFFMQMADTQYGFFSGNKGFDQEVDLVRRAVEHINRLQPRFVIVCGDLTNATPEHPRYREQVAQYHRDFSEVDAEIPLVCVCGNHDVGNRPTAESIARYKENFGDDYFSFWVGGVCNIVLNSSVLKDPEGAPEVLASQQTWLQQQLQEANAAKAKHILMFQHHPLFLAEEDEPDQYFNIPLQRRTPLLSQLKQADVRAVFAGHYHRNAYGTAGSMEMITTGPVGRPLGKDPSGFRIVTVHETGIEHRYWGMDDVPEKIEIETTSEAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1N1</accession>
    <name>A0A518J1N1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative glycosyl transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_52710</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="1">
        <location>
            <begin position="24"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="401" mass="44073" checksum="BD215A0DE02C49D0" modified="2019-10-16" version="1">MKRFQVLIVTRRYWPHCDDASSRLTALVSGLRRQGCYPTVLTPRYQATWPAEFQHREIPVLRPLAAPRGEWSMARYVRNLGKWLREQLPRFDLVYCDMMREEAAAVVETARQVGVPSVVRCGTLMGTQDIVWQASLRARRNTFVRSFAADAVIAPRASCQQALLVAGAKAATIVRIADGIGDPIRRTPESCKAARLTLGNMNHDLMVPVDGKVILCMNRLSPEGGVLTLASALWPLLEDQPDLRLWMIGDGPWRQKLFNDLKHNGVGRAAFLPGNFDHVEELMQAADMFVLPSAASGAESFWPAAIAAALPTAVVDCADTRAFAMAAFSELHSFPADSTDKMREAVQNVLDDLPMAAAGAQRMRSQLSTAASFSDTIRRHVQLFERLAGNTSAKNVSGATG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1V4</accession>
    <name>A0A518J1V4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Malonic semialdehyde reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_53450</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.109.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029479">
        <property type="entry name" value="Nitroreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000415">
        <property type="entry name" value="Nitroreductase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00881">
        <property type="entry name" value="Nitroreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55469">
        <property type="entry name" value="SSF55469"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nitroreductase" evidence="1">
        <location>
            <begin position="196"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="375" mass="43632" checksum="6A1878A2DC373478" modified="2019-10-16" version="1">MRQMHWRSDGYARRLRDVRSFMRYRITLPFYRRVMWPVALRIPFVTAIYFCFFDKSFWQEFQSTLAGKVTHYERNASGEGNSFLLRRNVHRLEKGLIMRPRRDLFATDYVGQTVDCLKALSFEEDPQLWKWAFDVLTEFFNATHESRKTDKARQAFQQLAFNNPRGIVSTEERFIPSRASKHSEISWEDFRQLAIDRRSVRWFSKEKVDRADVCKAMDIALLSPSACNRQPFKYLVFDDPKLIQAVATIPQGTVGFAHNFQMLVAIVGQLDAYALERDRHVIYIDGALSAMSFMFALETLGLSSCPINWPDSGENDLLMRKRFGLKAYERTVMLIAVGHHDCNGMVPRSTKKTPTQVAEFNRPLLTNDTFEAYPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1W3</accession>
    <name>A0A518J1W3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">D-inositol 3-phosphate glycosyltransferase</fullName>
            <ecNumber evidence="2">2.4.1.250</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">mshA_6</name>
        <name evidence="2" type="ORF">Mal33_53570</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.4.1.250" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102710">
        <property type="term" value="F:D-inositol-3-phosphate glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="172"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="343" mass="39197" checksum="18C1F87C0FB9F7A1" modified="2019-10-16" version="1">MYAKHRQRTQHLRVAHFQRKRSKTHFSVEGYFARVRECMESNINVTLHTAPFYSRGFFRRLGNVAWSLIHQADINHITGDITYLGIFLRKSRTVLTILDCQVLDRLQGWRRWIVVYLWFKIPVLRSQIVTVISAETKTKLLEFARVDESKIRIVPVSVSALYTPYPKPFETNLPRILQVGTKANKNIPRLLEALAGIPAQLTIIGPIDRALQANIDRLQIDVKNFVGLSDAELAEQYRAADLLAFVSTCEGFGMPIVEAQFVERPVLTSNCSSMPEVAGEGACLVDPFNVQSIRSGLRRIIDDGEYRERLIENGRINRDRFSKEQIAKQFAEIYLSLNGTYQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J217</accession>
    <name>A0A518J217_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase IS200 like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_54170</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002686">
        <property type="entry name" value="Transposase_17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036515">
        <property type="entry name" value="Transposase_17_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01797">
        <property type="entry name" value="Y1_Tnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01321">
        <property type="entry name" value="Y1_Tnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143422">
        <property type="entry name" value="SSF143422"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Y1_Tnp" evidence="1">
        <location>
            <begin position="4"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="154" mass="18115" checksum="3173F48DE071EDCF" modified="2019-10-16" version="1">MSTHHGILLHVIFSTKYRRRYLHDAWREEVFAYIGGTVKDHKAAMLKAGGIEDHVHLLLRIHPEFAISKTIQLLKTNASKWINEERKLPGRFQWQRGYGAFSVSQSMVEVVKAYISNQRAHHAQQTFEREYIGFLDKHKIQYDPKYVFESEFLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J219</accession>
    <name>A0A518J219_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_54110</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022144040" evidence="1">
        <location>
            <begin position="20"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="375" mass="41331" checksum="F45637A98C274782" modified="2019-10-16" version="1" precursor="true">MRPLLACLILLAIPRLALGCLFCEALASTLSDDIRESAACVIAQWDRDAAAPAPDIGMQLAKFRVTKVLKGDGRIGSQVDAYILPDEPPTGPVLLFAFGDPDAPQWSAPLPLAPVSVKYLNGLQTAPAAGSDRLGYFLPFLVAEDRHVADDAYNEFARSPFADIHGLGDRLDRQWVLDNLQAYLKDDTTPPHRIRLMWTLLSVCGEPEDAALVQRVIDDKTIDRNAIGWDAALGCYMSVAGPAGLEQVKQLLSSSDDEQTLFMALNAIRFHAVETKRFDQTELATALHPLLRNVRLAAYVIPDLARMEDWTVGPRLLELYASPDAAPIRIHIVNYFRTSPRPDAAESLATCRELDPTAVRRAELLFGNLRPRKDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J260</accession>
    <name>A0A518J260_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cytochrome c biogenesis protein CcsA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ccsA</name>
        <name evidence="9" type="ORF">Mal33_54540</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002541">
        <property type="entry name" value="Cyt_c_assembly"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045062">
        <property type="entry name" value="Cyt_c_biogenesis_CcsA/CcmC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007816">
        <property type="entry name" value="ResB-like_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30071">
        <property type="entry name" value="PTHR30071"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01578">
        <property type="entry name" value="Cytochrom_C_asm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05140">
        <property type="entry name" value="ResB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0201">Cytochrome c-type biogenesis</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="30"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="133"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="169"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="199"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="228"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="257"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="527"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="570"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="892"/>
            <end position="917"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="929"/>
            <end position="949"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="955"/>
            <end position="976"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="983"/>
            <end position="1003"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="1023"/>
            <end position="1047"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="1068"/>
            <end position="1090"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="1105"/>
            <end position="1122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="1129"/>
            <end position="1147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="1167"/>
            <end position="1185"/>
        </location>
    </feature>
    <feature type="domain" description="ResB" evidence="8">
        <location>
            <begin position="447"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrom_C_asm" evidence="7">
        <location>
            <begin position="956"/>
            <end position="1157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF05140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV59419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1201" mass="132169" checksum="956CD5842A358EC9" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J263</accession>
    <name>A0A518J263_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_54690</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="152" mass="17141" checksum="73E91EABEB8615B0" modified="2019-10-16" version="1">MLPATNQRVESHTCEAINREIAEQTQSRIAHYSTKSSREISERLRELDHEWDIERALECNASALAFSGVMLSATVDKRWLILPGLVTGFLFQHALQGWCPPLPILRRMGFRTSAEINEERYALKALRGDFERVNSSDSGQRDPRAAMAAAAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J2C0</accession>
    <name>A0A518J2C0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Type II secretion system protein F</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">epsF</name>
        <name evidence="9" type="ORF">Mal33_55230</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GSP F family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.81.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003004">
        <property type="entry name" value="GspF/PilC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018076">
        <property type="entry name" value="T2SS_GspF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042094">
        <property type="entry name" value="T2SS_GspF_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30012">
        <property type="entry name" value="PTHR30012"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00482">
        <property type="entry name" value="T2SSF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="110"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="153"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="298"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="T2SSF" evidence="8">
        <location>
            <begin position="14"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="T2SSF" evidence="8">
        <location>
            <begin position="206"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV59488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="336" mass="36642" checksum="51F196E2C0AAA350" modified="2019-10-16" version="1">MFSKGMSQSVAARFCRRMATGFHAGVDLLKLCQREAQHGSPKHKAAMEAVAAQLRDGTPMARAMIDVAEGKYFPPLMIQMVHIGETTGRLERTLKELADHYDHRLAMQRMFLMGIAWPMLQLIGGIAVIGLAILITQMLGSEFNAVGLNMTQYLTLVFLFFGSITSAVLALKFNAFGCHRLFALVYRIPKAGEALQTIALSRICWTLSLALDSGMDAMRSVKMALQSTQNDHFASRADTAIATIKSGGTLTESFASTGIFPEEFLHFVEVAELSGTDAESLGNLADVYDQRAKTATRVLVGVMTGVIWAAVTIMLVAIILKMAMSVFGVYDEALKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J2D6</accession>
    <name>A0A518J2D6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA 2',3'-cyclic phosphodiesterase</fullName>
            <shortName evidence="2">RNA 2',3'-CPDase</shortName>
            <ecNumber evidence="2">3.1.4.58</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ligT</name>
        <name evidence="4" type="ORF">Mal33_55320</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a 3'-end 2',3'-cyclophospho-ribonucleotide-RNA + H2O = a 3'-end 2'-phospho-ribonucleotide-RNA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11828"/>
            <dbReference type="Rhea" id="RHEA-COMP:10464"/>
            <dbReference type="Rhea" id="RHEA-COMP:17353"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:83064"/>
            <dbReference type="ChEBI" id="CHEBI:173113"/>
            <dbReference type="EC" id="3.1.4.58"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the 2H phosphoesterase superfamily. ThpR family.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.58" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004113">
        <property type="term" value="F:2',3'-cyclic-nucleotide 3'-phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008664">
        <property type="term" value="F:2'-5'-RNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01940">
        <property type="entry name" value="RNA_CPDase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009097">
        <property type="entry name" value="Cyclic_Pdiesterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014051">
        <property type="entry name" value="Phosphoesterase_HXTX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004175">
        <property type="entry name" value="RNA_CPDase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35561">
        <property type="entry name" value="PTHR35561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02834">
        <property type="entry name" value="LigT_PEase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55144">
        <property type="entry name" value="SSF55144"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02258">
        <property type="entry name" value="2_5_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LigT_PEase" evidence="3">
        <location>
            <begin position="10"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="domain" description="LigT_PEase" evidence="3">
        <location>
            <begin position="102"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="HXTX 1" evidence="2">
        <location>
            <begin position="43"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="HXTX 2" evidence="2">
        <location>
            <begin position="130"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="43"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV59497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="191" mass="21197" checksum="9297B06AC2913A73" modified="2019-10-16" version="1">MQKIRSFIAIPLTDEIQNAAGRMVDRLREPATGVKWVDADNLHLTLKFLGDVDNIEVPDVCKALRKCCANAEPFSLSIQGIGGFPDLQRARVVWAGVEDQSSGLCPLAESIDIEMGKLGFKREFRDYTPHLTLGRLKKGSRLGEDFVAAAEKEADTELGTIHVQEVHVFASFMDKHQKGPTYNVMDRVALD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IM49</accession>
    <name>A0A518IM49_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_01160</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021769792" evidence="1">
        <location>
            <begin position="23"/>
            <end position="2041"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="2041" mass="228319" checksum="1EB7390BFC62213A" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IM74</accession>
    <name>A0A518IM74_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Quinone oxidoreductase 2</fullName>
            <ecNumber evidence="2">1.6.5.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">qorB</name>
        <name evidence="2" type="ORF">Mal33_01510</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
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    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003955">
        <property type="term" value="F:NAD(P)H dehydrogenase (quinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
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        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="1">
        <location>
            <begin position="9"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="285" mass="30728" checksum="13DFD0CBF6D92AD9" modified="2019-10-16" version="1">MNQIAVTAASGQLGAEIVRATVEVVGAENVVGLARTPSKAESLGVEIRPGDYESRSDLASSLQGVDTVLLVSGMDAPDKRIGQHRNVIQAAKEAGVRKIVYTSIQGAEQGTAFSPIVQSNRQTEADVRGSGLLWAIGRNGIYIEPDVDYIETYKQRGEIANCAGDALCGYTTRGELAFAYARMLTQPQHDGQTYNLHGEAITQQQLADYLNSAFGTDLKFREMSVAEYREERIAELGDFLGNVIAGIYEGIRNGAANNKSDFATAAGRAHQSWADYFGQLTDRNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMB0</accession>
    <name>A0A518IMB0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ammonium transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">nrgA</name>
        <name evidence="10" type="ORF">Mal33_01800</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the ammonia transporter channel (TC 1.A.11.2) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008519">
        <property type="term" value="F:ammonium transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029020">
        <property type="entry name" value="Ammonium/urea_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001905">
        <property type="entry name" value="Ammonium_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018047">
        <property type="entry name" value="Ammonium_transpt_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024041">
        <property type="entry name" value="NH4_transpt_AmtB-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002229">
        <property type="entry name" value="RhesusRHD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00909">
        <property type="entry name" value="Ammonium_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00342">
        <property type="entry name" value="RHESUSRHD"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00836">
        <property type="entry name" value="amt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01219">
        <property type="entry name" value="AMMONIUM_TRANSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0924">Ammonia transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="77"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="114"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="167"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="194"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="232"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="273"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="310"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="340"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="362"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="394"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="423"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="domain" description="Ammonium_transp" evidence="9">
        <location>
            <begin position="78"/>
            <end position="475"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV54230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="485" mass="50204" checksum="0880233B5DB2A9E7" modified="2019-10-16" version="1">MLQVGRIPGWSLAIIAIGLLGVSLSLTSVAFAQDAEPATTEATEAAGVSDAPPVEEEVVVEEEVEAGSEVGYALDNAILFLCAVLVLFMQAGFAMVEVGLNAAKNTINILYKNVMDLSVGALLFFVIGFGLMYPGSYKEDPNPYFDFGGVGIYAASEGQTFSPDVDWFFQAVFAATAATIVSGAVAGRMQFKAYLIYSAILTGIIYPISGYWKWGGGWLTQFDGGLAFQDFAGSAVVHACGGFAGLAGAIILGPRLGRFASDGKSVPMPGHNIAFAALGVFILWVGWYGFNPGSQLAFQSAADIDATTFIAVNTTLSAAAGVVAATVVSWIMFGKPDLSMSLNGALGGLVGITANCDCFSNTWAIVIGGVSGVIVVAAIVALDKLKIDDPVGAFPVHGACGVWGCLAIGFLPNTHLDGGATNFMVQLIGTAAICAWAFFTMMVLFLILKAVGVLRCSAEEETAGLDISEHGMHAYPADSLAPAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMF4</accession>
    <name>A0A518IMF4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_02170</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011486">
        <property type="entry name" value="BBP2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07642">
        <property type="entry name" value="BBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="387"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="389"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="414" mass="45964" checksum="2DA6071C429312EF" modified="2019-10-16" version="1">MNLISRFFAIACICNAGLAVGQQFGHEEYPSESYPISGEGYEYQGDGGYYGDASCESCGPAPAKSCFASCLDGFTYGGWAQLGYYTYGSPMRFNNHPDRVNLSQMWLFAGKQANGAQGLDLGGRIDYVYGVDAQDTQAFGVDNGSWDTGWDNGIYGSAMPQLYGEAAYGNTSIKMGHFFTLIGYEVVSAPDNFFFSHSYTMVNSEPFTHTGALVTHKANEFVTVWGGYTLGWDSGYTDNGDNFLGGISVVLTDYTTITYTNTIGRLNENLELRGQDMKERGQMHSIVASTTVENFNHVLQIDRLDTKNQFDTFARDTFGINNYLFYDLADDVAAGLRFEWWNNRRDTNDHTDVYALTLGLNLKPKEFITVRPEVRWDWDVDAVPLGINEPNPNSPTNSPRSNQTTFGIDAIVTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMF7</accession>
    <name>A0A518IMF7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Octanoyltransferase LipM</fullName>
            <ecNumber evidence="2">2.3.1.181</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">lipM</name>
        <name evidence="2" type="ORF">Mal33_02050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.3.1.181" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033819">
        <property type="term" value="F:lipoyl(octanoyl) transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004143">
        <property type="entry name" value="BPL_LPL_catalytic"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03099">
        <property type="entry name" value="BPL_LplA_LipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51733">
        <property type="entry name" value="BPL_LPL_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="BPL/LPL catalytic" evidence="1">
        <location>
            <begin position="31"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="250" mass="27009" checksum="70CBB27B8312C180" modified="2019-10-16" version="1">MDARLIRHIDDPFDGAMNMAIDQALAESVDQGAAACLRLYRWKSPTLSLGYFQQYDDRQQHPWSADLSVVRRSSGGGAIVHDAELTYSLSIATPKSRHGADLTIYATVHNAIIETIAAIAMQTARRFADSGWLPLAADNAFLCFERRTDEDLVVSGYKIAGSAQRRVGRAILQHGSILLQTSPAAPMLPGLQCVSGKSCDPAQFADHLTATLSKALDADTSPAELSAAETTRAAEIAAARFSSPAWTHRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMI1</accession>
    <name>A0A518IMI1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Dipeptide and tripeptide permease A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">dtpA</name>
        <name evidence="3" type="ORF">Mal33_02500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006857">
        <property type="term" value="P:oligopeptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000109">
        <property type="entry name" value="POT_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018456">
        <property type="entry name" value="PTR2_symporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11654">
        <property type="entry name" value="PTHR11654"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00854">
        <property type="entry name" value="PTR2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01023">
        <property type="entry name" value="PTR2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="72"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="102"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="124"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="164"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="191"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="237"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="285"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="318"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="351"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="385"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="418"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="465" mass="50936" checksum="5DD182F388602926" modified="2019-10-16" version="1">MSNASQPTNPKFQTTPYPIDTMPPGIPYIVGNEAAERFSFYGMKAILTVFMTTYLLGGNGETDPMSDGDAKFWVHVFVMAAYFTPLIGAFAADWLFGKYKTILWLSILYCFGHLALALNETRIGLAVGLGLIAFGTGAIKPCVSAHVGDQFGSKNSHMLEKVFGWFYVAINLGAFASTLLTPWLLDRFGPQVAFGVPGILMAIATFLFWMGRNRFVHIPARGAVFFKDAFTGDGLKALLNLAPIYILVAVFWSLFDQTASAWVLQANHMDRTVFGFELLSSQIQAANPFLILILVPVFSYLIYPTFNKVFSMTPLRRVGIGMFLTVGAFSISALIETAIQNGGTPSIGWQVLAYIILTAAEVMVSITCLEFSYTQAPNSIKSIIMSFYMLSVSLGNFITAGVNAVISNDDGSSKLPGASYYWFFTGLMLVAAFLFIIVAYMYRGRTYIQDSAPETEIDAEASAMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMV9</accession>
    <name>A0A518IMV9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_03690</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="64" mass="7004" checksum="44B5DF7CD5E9B771" modified="2019-10-16" version="1">MSAGSLCERCAHVREIVSGKGSRFLMCRRGLASDQFAKYPPQPTLVCVGFESRGDGNEKGEHVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IN01</accession>
    <name>A0A518IN01_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Planctomycete cytochrome C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_04080</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011429">
        <property type="entry name" value="Cyt_c_Planctomycete-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011444">
        <property type="entry name" value="DUF1549"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022655">
        <property type="entry name" value="DUF1553"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07635">
        <property type="entry name" value="PSCyt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07583">
        <property type="entry name" value="PSCyt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07587">
        <property type="entry name" value="PSD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022195996" evidence="1">
        <location>
            <begin position="26"/>
            <end position="964"/>
        </location>
    </feature>
    <feature type="domain" description="PSCyt1" evidence="4">
        <location>
            <begin position="56"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="PSCyt2" evidence="2">
        <location>
            <begin position="205"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="domain" description="PSD1" evidence="3">
        <location>
            <begin position="621"/>
            <end position="884"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV54454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="964" mass="108415" checksum="42DF24034F1001C4" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IN74</accession>
    <name>A0A518IN74_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">D-aminoacyl-tRNA deacylase</fullName>
            <shortName evidence="1">DTD</shortName>
            <ecNumber evidence="1">3.1.1.96</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Gly-tRNA(Ala) deacylase</fullName>
            <ecNumber evidence="1">3.1.1.-</ecNumber>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1 2" type="primary">dtd</name>
        <name evidence="2" type="ORF">Mal33_04880</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a D-aminoacyl-tRNA + H2O = a D-alpha-amino acid + a tRNA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13953"/>
            <dbReference type="Rhea" id="RHEA-COMP:10123"/>
            <dbReference type="Rhea" id="RHEA-COMP:10124"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:59871"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:79333"/>
            <dbReference type="EC" id="3.1.1.96"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>glycyl-tRNA(Ala) + H2O = glycine + H(+) + tRNA(Ala)</text>
            <dbReference type="Rhea" id="RHEA:53744"/>
            <dbReference type="Rhea" id="RHEA-COMP:9657"/>
            <dbReference type="Rhea" id="RHEA-COMP:13640"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78522"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="1">A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DTD family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.96" evidence="1"/>
    <dbReference type="EC" id="3.1.1.-" evidence="1"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051499">
        <property type="term" value="F:D-aminoacyl-tRNA deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106026">
        <property type="term" value="F:Gly-tRNA(Ala) hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043908">
        <property type="term" value="F:Ser(Gly)-tRNA(Ala) hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019478">
        <property type="term" value="P:D-amino acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00563">
        <property type="entry name" value="Dtyr_deacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00518">
        <property type="entry name" value="Deacylase_Dtd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003732">
        <property type="entry name" value="Daa-tRNA_deacyls_DTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023509">
        <property type="entry name" value="DTD-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10472">
        <property type="entry name" value="PTHR10472"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02580">
        <property type="entry name" value="Tyr_Deacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69500">
        <property type="entry name" value="SSF69500"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00256">
        <property type="entry name" value="TIGR00256"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1" id="KW-0820">tRNA-binding</keyword>
    <feature type="short sequence motif" description="Gly-cisPro motif, important for rejection of L-amino acids" evidence="1">
        <location>
            <begin position="137"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="149" mass="16390" checksum="6FFBE69C608D319B" modified="2019-10-16" version="1">MRAVIQRVSEASVTVDDQVVGSIELGFLVLLGVENGDTETDANYLADKTIGLRVFADPDDKMNLDIAQVGGKVLAVSQFTLLGDCRKGRRPAFTDAADPEIARQLYEHYCQRIRTAGIEVQTGIFAADMQVHLVNQGPVTLLLDSRKRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INL5</accession>
    <name>A0A518INL5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_06330</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="47" mass="5388" checksum="44DAAA10AE6B5814" modified="2019-10-16" version="1">MFTTTFSRCPTAEEMPRLLSLIGDQKKDAYEGTLWSLLNSTESTFNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INV3</accession>
    <name>A0A518INV3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Phthiocerol synthesis polyketide synthase type I PpsE</fullName>
            <ecNumber evidence="7">2.3.1.41</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ppsE_1</name>
        <name evidence="7" type="ORF">Mal33_07320</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.3.1.41" evidence="7"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032821">
        <property type="entry name" value="PKS_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16197">
        <property type="entry name" value="KAsynt_C_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="SSF55048"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="B_KETOACYL_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PKS_KS" evidence="5">
        <location>
            <begin position="17"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="domain" description="PKS_AT" evidence="6">
        <location>
            <begin position="543"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="898"/>
            <end position="958"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="922"/>
            <end position="936"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV54767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="988" mass="106612" checksum="FDA0EDF5F96CC22F" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INW9</accession>
    <name>A0A518INW9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">ATP-dependent 6-phosphofructokinase</fullName>
            <shortName evidence="10">ATP-PFK</shortName>
            <shortName evidence="10">Phosphofructokinase</shortName>
            <ecNumber evidence="10">2.7.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Phosphohexokinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10 12" type="primary">pfkA</name>
        <name evidence="12" type="ORF">Mal33_07120</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6-bisphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16109"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 10">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 3/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homodimer or homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.11" evidence="10"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00182"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003872">
        <property type="term" value="F:6-phosphofructokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047334">
        <property type="term" value="F:diphosphate-fructose-6-phosphate 1-phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006002">
        <property type="term" value="P:fructose 6-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.460">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01976">
        <property type="entry name" value="Phosphofructokinase_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022953">
        <property type="entry name" value="ATP_PFK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012003">
        <property type="entry name" value="ATP_PFK_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015912">
        <property type="entry name" value="Phosphofructokinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000023">
        <property type="entry name" value="Phosphofructokinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012829">
        <property type="entry name" value="Phosphofructokinase_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035966">
        <property type="entry name" value="PKF_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00365">
        <property type="entry name" value="PFK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000532">
        <property type="entry name" value="ATP_PFK_prok"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00476">
        <property type="entry name" value="PHFRCTKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53784">
        <property type="entry name" value="SSF53784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00433">
        <property type="entry name" value="PHOSPHOFRUCTOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 10" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="7 10 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="8 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PFK" evidence="11">
        <location>
            <begin position="15"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="149"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="193"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="295"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="151"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="23"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="86"/>
            <end position="87"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="126"/>
            <end position="129"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="127"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="186"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="246"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="289"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="site" description="Important for substrate specificity; cannot use PPi as phosphoryl donor" evidence="10">
        <location>
            <position position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QDV54752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="382" mass="40779" checksum="D1C8C858ACB5C493" modified="2019-10-16" version="1">MTAFDATTIDSTRPRIGILTAGGDCPGLNAVIRGVVKSAYRMGYETLGFEGGFEGLVDPIRCRSLTPQNTSGILTLGGTILGSTNRGRFGVTVGEDLKLSLPEPMIEAVRQTFQKTQLQGLICVGGDGSLSIALELHRAGLPVVGVPKTIDNDLSCTAFTFGFDSAVNCATDALDRLHTTASSHDRVMVLEVMGRHAGWIALHAGIAGGGDVILIPEIPWSYEGIIAKIDDRRRMGKNFTLVVVAEGAELPSGAVVTRESVQTDRQTLLGGIGNEISQQLNKRIEQEVRYVVLGHLQRGGGPTNFDRVLATQLGVHAVRLVVQKRFGEMVCYQPPQIDSVTIAEAVGELRRVPPDSSAVAAARAMGISFGDTLDYINPFLPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPE1</accession>
    <name>A0A518IPE1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_09140</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="450" mass="48969" checksum="991F7AE50B8CB3A7" modified="2019-10-16" version="1">MGEQKSKRGRNVAIALAAIGLAGFLILCAGILTWRASSKAKLEKQLDRMRANGQPTTAAELSKHYVIPAGAEDATQLWIDACTPLDTEQFRLAGTDLPIVGANSPLEIPPPGTPWKEQAAVQQLLNTYADSMQLMHQATALGGYARFDHDFTQGIALLLPNVLSLRSGAGLLKLEAHTNAHRGDPAACLQSLEAMFTIGRGVENDPILVSQLVMIALDSMAVQTTVELLPHLQWNDSQLQRLQELTRRTNYLATVRNSILGQQVLGRLAFDNPALMDEEITQLPGLPLFGNEDQSLYLELMGDFIEGTQVSWAESFRAAGSAQTKLTEATKSPLNRIRYMLTTLVFPAIDAVITAGARADSYAKLTDVLIAAQRYKLAKSEYPKTIEELVPTYLPSVPIDPHDNAPVRYALRDGYPIAWCVGIDMVDDDGIGGDKAEPDVALTLNPSKKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPG9</accession>
    <name>A0A518IPG9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">O-Antigen ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_09350</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007016">
        <property type="entry name" value="O-antigen_ligase-related"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04932">
        <property type="entry name" value="Wzy_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="2 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="52"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="81"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="110"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="135"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="185"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="214"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="252"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="338"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="375"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV54967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="423" mass="46134" checksum="8539B1AAF24D5767" modified="2019-10-16" version="1">MATVAYSRVDERPVATSGSGRLVTSFVGALVFAVVFLNAADFRGDTGEEFSVHWQIYLRLLICAVCGGTGILLVSKSYRAFLTFPGFLITLLIAWIGVTLPFSVDRTYSLAAYVSLGAVAMLIPAAMQILGGYRYLMIVAAGLVTFIVGSWIAYLVFPEIGIFKEQITQTEVLERMGGLGHPNELGLYSAFTTVLFAVLGYGRRLSYLIVVPAMLLSLVTLVVCFSRTSMGITLVGLLVVYRKELFTQQTVIATLLLAILAIPPIFVVAGTGGFDWLVGDALEKLSKSGTADELTTATGRTDIWAYAIQRIGEQPLHGYGYMTARFVMEKYSYHCHNIVLNMCLNTGVIGGMTLLSMVLYFVYAIYHDPRYEVDGLVAVILAGGLIDGLLFAAVPSAAVLIWFSALLWRQLDMQFDPPQPKTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPK2</accession>
    <name>A0A518IPK2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 8">D-3-phosphoglycerate dehydrogenase</fullName>
            <ecNumber evidence="8">1.1.1.95</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">serA_1</name>
        <name evidence="10" type="ORF">Mal33_09700</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 8">
            <text>(2R)-3-phosphoglycerate + NAD(+) = 3-phosphooxypyruvate + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:12641"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18110"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58272"/>
            <dbReference type="EC" id="1.1.1.95"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(R)-2-hydroxyglutarate + NAD(+) = 2-oxoglutarate + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:49612"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15801"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.399"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4 8">Amino-acid biosynthesis; L-serine biosynthesis; L-serine from 3-phospho-D-glycerate: step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 8">Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.95" evidence="8"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00135">
        <property type="reaction ID" value="UER00196"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004617">
        <property type="term" value="F:phosphoglycerate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006564">
        <property type="term" value="P:L-serine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029009">
        <property type="entry name" value="ASB_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006139">
        <property type="entry name" value="D-isomer_2_OHA_DH_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029752">
        <property type="entry name" value="D-isomer_DH_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006236">
        <property type="entry name" value="PGDH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045626">
        <property type="entry name" value="PGDH_ASB_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00389">
        <property type="entry name" value="2-Hacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01842">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19304">
        <property type="entry name" value="PGDH_inter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143548">
        <property type="entry name" value="SSF143548"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01327">
        <property type="entry name" value="PGDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00065">
        <property type="entry name" value="D_2_HYDROXYACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0520">NAD</keyword>
    <keyword evidence="8 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8" id="KW-0718">Serine biosynthesis</keyword>
    <feature type="domain" description="ACT" evidence="9">
        <location>
            <begin position="456"/>
            <end position="535"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00021582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV55002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="542" mass="57819" checksum="8993EC882055BF7F" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPQ7</accession>
    <name>A0A518IPQ7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative HTH-type transcriptional regulator YjiR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">yjiR</name>
        <name evidence="3" type="ORF">Mal33_10480</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="2">
        <location>
            <begin position="23"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="465" mass="50485" checksum="44073933CEEFDD8B" modified="2019-10-16" version="1">MVVKNKTSQRRDEWLPDVERADIPIYLAVAEAIAADIQDGRLRGGDHLPTQRTLAKRLNLDVTTVARGYSEAARRGLVEARVGAGTFVRRSSPQPTRVGRQFDLADRSMNQPPDVADPDVLTAIADSFQVVSESMPSVLRYQPLGGSMRDRAAAIRWLSNRGIDAGPEAVYVTAGAHVALGAIVAKIGSPDDVIGCDQITYSGIKEVASTLRRRLMGLPGDAHGMLPAALDRAARENRVRVVYVNPTLRNPTVETMPIQRRSEIVQVARKHGIAIIEDDAYGMLPTAGPPPFAALAPEITFYVTTLAKCLAPGLRIAYLVAPRDQRASGVLSALRAVSVMASPVCATLATYWIESGLADAVLASVRSSTRARQRLLKRYLPADIVQTDEHAFHAWIRLKKPWTRAHLVDWMRGYALGVVASDRFCVDIEAPEALRVCLGGAASLQETELAIQALWGALQTEPNAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQ56</accession>
    <name>A0A518IQ56_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transposase DDE domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_11990</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025668">
        <property type="entry name" value="Tnp_DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13751">
        <property type="entry name" value="DDE_Tnp_1_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tnp_DDE_dom" evidence="2">
        <location>
            <begin position="322"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="177"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="290"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="290"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="462" mass="52237" checksum="AB6C62FE8E610E17" modified="2019-10-16" version="1">MERQVNTLDRTPVDQAYAGVGKVAYDPIVLLKMTLYQLLLGNHSPTTWHAEAARNSTMKWLGRGYRPARSVWYDFRDRVSKFIDQLHHQSTNSAIDQGHLAPGTGALDGSSVAACASRHRMVNSATLQKRKAILQRLADGEELKSSEIPRWVPATLRGRSNLLDRMHRAEEVLQQRLQENKARRSDRRKHPDKVVVSLSDPDAPLGLDKRKTYRPLYTVQKMVDPVSHLTISYTCEAAAGDAGMLAPMIDKTQQIVGGRLKKVLADGGYCSILDVKDSIDRQVELFAPVSASGTTRQNKSRSGEPQLPREQFQFKPESNHYVCPRGEILRYKDREKRKRNGGRRLYEYRYQCDTSICNACPLVEQCLSGKGGRMIRRSEGEELLEAQREKMQTDSAKQLYALRGQSVELVFADDKGNRRHDRFHGRGLARVRAETGLITLARNLFRLDKLQQSAKNSTKATP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQY6</accession>
    <name>A0A518IQY6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_14770</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="420" mass="46692" checksum="857B8D9819C8FB66" modified="2019-10-16" version="1">MNQLACKEHATLLYIDSSLRSHRGHHANVCEAITSAARSQGHRVQIAISQKKTDACEGEKVFSQDVYCNMKRNPDAFVDRMRLKLASSRVSREVLPILQRTRPHAIYAHSVNAVVCEGILQAIGKAFLPGGAPFFMAEMPFPCEPSERYFYGEQLRAMFERLNGRAAAARRRSQANLLDRFAPITVNERTSDLLSQSTGVEIGVMPSPYAVRSRRGQEHKHRSTPLRIGSVGHQSEHKGFDLLPAIIESLGNQKHKIQWVIQHQDESNPATLEQLKTLQQKGFDIELVHRDLTPSDYEKLLLGLDVILLPYKPQRYQSAISGICYEGLSQGSVVIAPRHTTVGKIVHEFQPETPQFEDWTSESIAAAVRKSVENADPIGDAALAGASLYAETNGPDVYARRIMSPALQDLALIQPDRSVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IR23</accession>
    <name>A0A518IR23_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_15240</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="54"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="103" mass="11120" checksum="1C76C3D61A7C8D1A" modified="2019-10-16" version="1">MRRSARLRGGLGTCGFAVASALFGCLLLVLNGGVVAAIYFAIAENGPQWMRNRSLSQFALYVGPVLLLILQWTMIDWVGRDRGSETSPSSQAIDSDRADSTKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IR54</accession>
    <name>A0A518IR54_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ATP-dependent Clp protease ATP-binding subunit ClpC1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">clpC1</name>
        <name evidence="4" type="ORF">Mal33_15370</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1780.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036628">
        <property type="entry name" value="Clp_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004176">
        <property type="entry name" value="Clp_R_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02861">
        <property type="entry name" value="Clp_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81923">
        <property type="entry name" value="SSF81923"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021948841" evidence="2">
        <location>
            <begin position="29"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="Clp R" evidence="3">
        <location>
            <begin position="62"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="Clp R" evidence="3">
        <location>
            <begin position="142"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV55560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="201" mass="21725" checksum="EBE737678B308E86" modified="2019-10-16" version="1" precursor="true">MAHSRRRFFQASALGTAMFAVSSSDTQAASDARTAPALDLEAQPISVLKRLSHRSRRALRFAVDEAAETGDGMVSSNYLLIGLAAEAEYSGASWLANLGLTLDDLCTVSEKLRLASTRLHESNNHLPVSQAARQCVLDGIAEAMRMGYQKAEPEHLLLGILQNPDVDAQLLLHEMWIDAAGLASEALASMPTWGSVHHRFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRA9</accession>
    <name>A0A518IRA9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Peptidase T</fullName>
            <ecNumber evidence="9">3.4.11.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">pepT</name>
        <name evidence="9" type="ORF">Mal33_16060</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6">Binds 2 Zn(2+) ions per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M20B family.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.4" evidence="9"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045148">
        <property type="term" value="F:tripeptide aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006518">
        <property type="term" value="P:peptide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001261">
        <property type="entry name" value="ArgE/DapE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010161">
        <property type="entry name" value="Peptidase_M20B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42994:SF1">
        <property type="entry name" value="PTHR42994:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037215">
        <property type="entry name" value="Peptidase_M20B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01882">
        <property type="entry name" value="peptidase-T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00758">
        <property type="entry name" value="ARGE_DAPE_CPG2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="3 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="M20_dimer" evidence="8">
        <location>
            <begin position="213"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="359"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="85"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="178"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="144"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="201"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="384"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR037215-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR037215-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV55628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="414" mass="44635" checksum="0B9B176D082E4A47" modified="2019-10-16" version="1">MIVPVNRERLLQRFLQYVQIGTSADPHSETYPSSPQQKDLSRVLAEQLVALGVADAHMDDHGLVWGTVPANVAGAPAIALNSHVDTSPEAPGDDVKPQVIVYQGGDIPLPEDNQVIRVADCPELADLVGKTLITTDGTTLLGGDDKAGVAIIMELVATLIENPQLPHGPVKILFSCDEEIGHGTDKIDLAQLDAVAAYTLDGGGAGDLDVETFSADGVLVTFTGRNIHPSIGKGRMVNATRAAGFFLQQLPDDSLSPESTDGRDGFIHPYEIEGGVGRAELRVLLRSFDTAELTQYADRLRQAATATEQQYPGLAVRVEVKPQYRNMADGLRENPRVADLAEQAFRNLGRPVRRSIIRGGTDGSALTEKGLPTPNLSSGQHAIHSLHEFACLEEMIEAVEHLQELLRLWSETTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRJ7</accession>
    <name>A0A518IRJ7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acetyl esterase Axe7A</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">axe7A</name>
        <name evidence="3" type="ORF">Mal33_16520</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008391">
        <property type="entry name" value="AXE1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039069">
        <property type="entry name" value="CE7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40111">
        <property type="entry name" value="PTHR40111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05448">
        <property type="entry name" value="AXE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022079329" evidence="1">
        <location>
            <begin position="29"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="domain" description="AXE1" evidence="2">
        <location>
            <begin position="139"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="448" mass="47809" checksum="661CBE0CBDAF1C31" modified="2019-10-16" version="1" precursor="true">MRRFSALRSHAMLLAFALPIFLSTASLAAAEGYAVSVAADRDDAIYDSGEAAAFVISVTRGDQPVTDGKLTYVVDDFLRSGKSGGYPEGEASLDGKPVRVAVKSDKPNVLRCQVTYTPAEGKPIRRLAGLAFSPTEIEPSMPVPDDFDAFWADQKKQLAEVEITPTLTPVEQKNNKIACFDVQVPCLGGAPVSGYFAKPVGAEEKSLPAILWVHGAGVRSSSLYAATKGANAGMLSMDINAHGIPNGKPAEFYAQQSGGPLKNYRYAGRDSRDTIYFRGMFLRLVRAIDFLTMQPEWNGREVIVIGHSQGGGQALVAGGLDPRVTLIASGVPAICDHTGNVAGRVNGWPKLVPNGPDGKPEPAALEASRYVDSVNFASRCKADAIMSVGFVDVTCPPTSCYAAYNALLGEKTMISEPLMGHNAPKHIHKAFFDRVLQHVEQSQPAAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRM4</accession>
    <name>A0A518IRM4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ImpA_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_17190</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010657">
        <property type="entry name" value="ImpA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017740">
        <property type="entry name" value="TssA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37951">
        <property type="entry name" value="PTHR37951"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06812">
        <property type="entry name" value="ImpA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03363">
        <property type="entry name" value="VI_chp_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ImpA_N" evidence="2">
        <location>
            <begin position="15"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="359" mass="39603" checksum="95623CD9F17640B1" modified="2019-10-16" version="1">MHVTSPATFDIDALLQAIDSERPSGDGRAYARGLRAELAELRNPPRSANPDDQDTDGGPDCVDWMAITMVATEALCEKTKDLRIACHLTEAAMQHWGIAGLRDGLILMRRMVEQFWDTLAPELDPDDPDARCSPLENLLDDPNRGPRMPSVLRALPILNAGVHKFSLMTATRQSEDLTSAEIATAIRQVTVQDACLLSEEVDGAIAELESFHQVLVDRMGEYAPSFVHLEESLHVIRQWLDSVLKPQFESRDIVDAEEAVMPQAKTPATTDTSDSTAIVATTQQLRAQTYKQLTEAANVLRQIEPHSPIPFMVQRAARLGQLPFPELMAQLVNEESTLEMFHRELGLSASGDQASGIDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRR0</accession>
    <name>A0A518IRR0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Long-chain-fatty-acid--CoA ligase</fullName>
            <ecNumber evidence="2">6.2.1.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">lcfB_1</name>
        <name evidence="2" type="ORF">Mal33_17430</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="6.2.1.3" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004467">
        <property type="term" value="F:long-chain fatty acid-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="1">
        <location>
            <begin position="10"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="519" mass="55190" checksum="02DFD45A91227D69" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRS6</accession>
    <name>A0A518IRS6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_17770</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008930">
        <property type="entry name" value="Terpenoid_cyclase/PrenylTrfase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48239">
        <property type="entry name" value="SSF48239"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="72"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="534" mass="59706" checksum="00E5B19A9FA029A2" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRY7</accession>
    <name>A0A518IRY7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_18230</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021908937" evidence="3">
        <location>
            <begin position="22"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="37"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="314"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="115"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="204"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="42"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="314"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV55844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="381" mass="42073" checksum="DEDA3DB8F31DC710" modified="2019-10-16" version="1" precursor="true">MSMLFRSLALLLLAVPLAASPAVGQYQALAHGERVISVGPPIPPKQAEPDSSPKRLPSPPCTVDCEKAANRNAPAAPAAAPTGDSVLQINRPQNHVDAAVPADKPDDLPAPPDLAAQLREATANFQHDLNQANQRIDHLTKQLQLCEQAAAKQAEAKPALEKLQATIEAMRKTHAEELAAADVRLKTLVDEISAGLASKREMQQQREQALKSKLAEQMQSLQKQAAAAKMEAIAKAEENRELAEQFEATKKLHAQNVTRFGERAEEMKALMIERSKAVDAASKQVRELRGTLANKLRALEDSLATTELMKKKTAELEKQSAAMEKEHQAALDQLKQANKRNESLQRRQKSLEKELTALKRNRDSDRRDDKKRKPKKKRDDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IS41</accession>
    <name>A0A518IS41_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_18730</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="51" mass="5679" checksum="0DBD6987EE611296" modified="2019-10-16" version="1">MKTDTILEAPQTSETLPQPQTLEQIIDRVAVDAQDQPQRYLDEVVVPDGGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IS54</accession>
    <name>A0A518IS54_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_18890</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025352">
        <property type="entry name" value="DUF4256"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14066">
        <property type="entry name" value="DUF4256"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="190" mass="20972" checksum="2719D61B9C3122AB" modified="2019-10-16" version="1">MKKKRASSPASAESAGDLLTILASRFAANKGRHKGIRWTDVQAKLDASPEKLAVIERMEQTGGEPDVVGRDKKSGEFIFYDCSLESPSGRRSVCYDREALESRKSHPPQNNALDLAAAIGIELLNEEQYRELQSLGDFDTKTSSWIQTPAEIRALGGALFGDFRYGHVFIYHNGAPSYYAARGFRGSVRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IS65</accession>
    <name>A0A518IS65_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">VWFA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_19140</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002881">
        <property type="entry name" value="DUF58"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01882">
        <property type="entry name" value="DUF58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VWFA" evidence="1">
        <location>
            <begin position="82"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="301" mass="34344" checksum="E9CE4EA156576E12" modified="2019-10-16" version="1">MPDSKRFLRPEAARRVARLELKARRVVEGFLSGMHRSPYFGQSIEFLQHRQYVAGDDIRHIDWKVWGRQDRLHIKQYEEETNFRMHLLVDSSASMNYGSGEENKFEYASSIAASLAFLANRQQDATGLITFDDKIRRNLSPRTSRYQLARILDALDGASQNSTTDLFSIVREVAESVPRRGVIVLISDLLGVGDSLVKSLSLLRKRGHDVIVFQTLHDEEMEFPFSGATRFEGLESEQFLNCNPRALREGYLEALNAFLENTRRACARLSIEYELVRTNQPLDAVLAKFLSARSNMPTLKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISP9</accession>
    <name>A0A518ISP9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_20970</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010869">
        <property type="entry name" value="DUF1501"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07394">
        <property type="entry name" value="DUF1501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="497" mass="55233" checksum="D3108A75D3410B9C" modified="2019-10-16" version="1">MNNESVSSELQRLRLQHQTRRHFLRSCPTGLGALWLAMQNSPGYAAPSQALPVHDANNPLSPIQPPLPAKAKRVIFLHMIGAPSQLELFDYKPDLKRLDGHDCPQSFLEGKRFAFIQGTPKMLGPQYPFEQHGESGAWVSDRMPHFAKHVDDVCFIKTMVTDQFNHGPAQLMVHTGQARMGSPSIGSWATWGLGSENEDLPGFMVLLSGGRQPRVGKALWSGGFLPSVYQGVQCRSQGDPVLDISNPAGVSRDQRRQVLDALSKLNQRTSIEFGDPETLTRIAQYEMAFRMQTAVPDAMRIDDEPAHVHAMYGTQPGKESFANNCLLARRLAERDVRFIQLFDWGWDSHGAGKDEALNEGFKSKCQQIDRPIAALLADLKQRDMLKDTLVVWSGEFGRTPMRENRGGTEMRFVGRDHNPGAFTLWMAGGGTKPGMTYGETDAVGYSAAINPVQLRDFHATMLHLLGFDHNRFSFPFQGLDQKLTGVKPATLIKDVLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISQ1</accession>
    <name>A0A518ISQ1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RNA polymerase sigma factor SigA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">sigA_4</name>
        <name evidence="6" type="synonym">sigA</name>
        <name evidence="8" type="ORF">Mal33_20940</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Interacts transiently with the RNA polymerase catalytic core.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the sigma-70 factor family. RpoD/SigA subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00963">
        <property type="entry name" value="Sigma70_RpoD_SigA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000943">
        <property type="entry name" value="RNA_pol_sigma70"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009042">
        <property type="entry name" value="RNA_pol_sigma70_r1_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007624">
        <property type="entry name" value="RNA_pol_sigma70_r3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007630">
        <property type="entry name" value="RNA_pol_sigma70_r4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007127">
        <property type="entry name" value="RNA_pol_sigma_70_r1_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042189">
        <property type="entry name" value="RNA_pol_sigma_70_r1_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028630">
        <property type="entry name" value="Sigma70_RpoD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03979">
        <property type="entry name" value="Sigma70_r1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00140">
        <property type="entry name" value="Sigma70_r1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04539">
        <property type="entry name" value="Sigma70_r3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04545">
        <property type="entry name" value="Sigma70_r4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00046">
        <property type="entry name" value="SIGMA70FCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00716">
        <property type="entry name" value="SIGMA70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="5 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 6" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="RNA_pol_sigma70" evidence="7">
        <location>
            <begin position="498"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="6">
        <location>
            <begin position="499"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="region of interest" description="Sigma-70 factor domain-2" evidence="6">
        <location>
            <begin position="305"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Sigma-70 factor domain-3" evidence="6">
        <location>
            <begin position="384"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Sigma-70 factor domain-4" evidence="6">
        <location>
            <begin position="473"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Interaction with polymerase core subunit RpoC" evidence="6">
        <location>
            <begin position="329"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV56115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="541" mass="62775" checksum="2DD329BA7A98A95D" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISS0</accession>
    <name>A0A518ISS0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">L,D-transpeptidase YkuD</fullName>
            <ecNumber evidence="5">2.-.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ykuD</name>
        <name evidence="5" type="ORF">Mal33_21170</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <dbReference type="EC" id="2.-.-.-" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16913">
        <property type="entry name" value="YkuD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005490">
        <property type="entry name" value="LD_TPept_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038063">
        <property type="entry name" value="Transpep_catalytic_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141523">
        <property type="entry name" value="SSF141523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="SSF54106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="LysM" evidence="4">
        <location>
            <begin position="278"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="76"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="76"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="179"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV56138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="446" mass="46196" checksum="2E32375719AC0836" modified="2019-10-16" version="1">MQTIKTAVVTVLLLVVLYGAYVAINTPPVMMPDELQALVEQDGLQIDDGAIDVPEIEVPPFGDSFGGTISSTQNGVVASLSSDSPDSTGEDSSADSDPLAALPPLNFGSDDSATTESDSRDDEVSAAPLMTQALPKPAGSSPAIAADPDQTYPETPMAGLSLSGPAGPAGDEAESVPSAEASLSDSGSGFQMPSDPNAAAAEQPAAETPSSDSAAGIDNAIQTADRQVAAGELREALFTLSLFYGSPDLTDEQVQQLMPRLNALAGEVVYSRRHLIESAYRVQPGDTLQSIADARHVPVQVLANINGITDPASLVPGTELKVFTGPFRAEIDLSNSKLALFLGDLFAGAFAVKTGTSPSPVEGTFAIQAKQKARAYYGMDGTTFAAGDPRNPYGEFWIDLGDRLSIHGSPSMQPGVSGLGCIQMNTADARDVYGILSEGSSVTIRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISS6</accession>
    <name>A0A518ISS6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF218 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_21230</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003848">
        <property type="entry name" value="DUF218"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02698">
        <property type="entry name" value="DUF218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="208"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="DUF218" evidence="2">
        <location>
            <begin position="41"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="242" mass="27570" checksum="AF307CF39B2654DF" modified="2019-10-16" version="1">MIRRVGFAMLLIFGLLWASHAQLLRAVANGLDVSEPILPSDYVVVLPGGPETRTFAAVVILREGLAKRTAILRNPETNAVQEGLRLPTHEMTQRIFQERGIAEERMFFLDGESRTTHSDLELIGSILETDTDATITIVTNRFHTRRARWAAARIYGEKLERFSFVGAPSDAFVWETWWQSQRGLDLILAEYLKLGYYMVVYSTSMQRLAVVAIALGSTLVAVVWLRRRRRIFDLHHEQAQQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISU8</accession>
    <name>A0A518ISU8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HPP family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_21460</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="HPP"/>
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    </dbReference>
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    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="133"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="221"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="277"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="310"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="334"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="372" mass="40387" checksum="1499783915CB14B4" modified="2019-10-16" version="1">MPPLPFAEVSESSVLNGEEIDAGVREQTNAHVLRCLRPVELDLPLLTPSITFYQHIMELRFTALFMAIVSGIASITNFSLIYFPELGALSYEVFKNPSGKWAKHKWHLAMVPMLTGIVGAACAIYLPYGFASMILSVGLSIAILIVLRSPIAPAISAGFFPVVLGVDTWWYPMAILGGTSSLALTRYAMDQVQPPSPLTFDHSEVEPTDDQRNSAPHVGSAIVRLLVFGLLTMAIANLFDNKLILFPPLIVIAFELFLHPIDCPWSTSLWKLPTTCLATATIGVLAVALLGPGVISTALTVVLGIVALKLIRLHIPPAIAVGLIPQILEDPIHWYPLSVGVGTSILVAFELASSAMFRIYLNKTRVQFDSPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IT22</accession>
    <name>A0A518IT22_9BACT</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_22110</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="53" mass="5775" checksum="32ED9EC14E6DECFC" modified="2019-10-16" version="1">MAQSSGVTQCPKCGSVGTYPIRMQQGGQVITCNNCRKNFTAQVDHGQFIGRNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IT26</accession>
    <name>A0A518IT26_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GYF_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_22120</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="244"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="278"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="GYF_2" evidence="3">
        <location>
            <begin position="5"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="329"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="330"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV56230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="452" mass="49544" checksum="BAF5FBB53FD03231" modified="2019-10-16" version="1">MANQWYYKREGERFGPVGDSDLRKLAADDALKPNDQIWKEGMAKWRTAGSVKGLFLQSVPPPLPPKPAVVVNDIPPKIDDNQEESVSFGGSAKLASLLAAKQAEFTKIQQVLLPKEYHVIGQRTFESQFERENHETHFSEIEKLNHNIAELESAEATSPQAKTFTDKAKSLGNQAVIAGRLKTAQFQRRQKLIALGKSACSIGNMPQDCLDEQENIGGLLERSEILQSEIDVLKKEASAAGKSLMASTAVVASFACLCAPIGLLLIWRHPTWSKDAKLKWAGASIGCFLLLGIIGQSKSKPDREWLEYNGNMISTEGLSNEKIAELKASGAKSTRSSDSESTVFDGSESNTDLNEIARGVAFRIKNENLWSSMTPNGFHLGLEEAVRSAGRADLLPLRAKSTDNHDTLSNITTIYMEYNKNFGVGFAIDHSNSSRSKMTCSKIWLDGAEIGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITC1</accession>
    <name>A0A518ITC1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl hydrolases family 2, TIM barrel domain</fullName>
        </submittedName>
    </protein>
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        <name evidence="3" type="ORF">Mal33_23210</name>
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        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006103">
        <property type="entry name" value="Glyco_hydro_2_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02836">
        <property type="entry name" value="Glyco_hydro_2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_hydro_2_C" evidence="2">
        <location>
            <begin position="115"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="602" mass="65122" checksum="B42CC254D594253F" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITG6</accession>
    <name>A0A518ITG6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_23710</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021999865" evidence="2">
        <location>
            <begin position="29"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="485" mass="51862" checksum="963D53F4D7909C7C" modified="2019-10-16" version="1" precursor="true">MITTQPLSRIQCSLALAFALILTNLATAAEDQTVPTNSLRAPVKPKQTWVPEATPAAEAAAAPQTVEPPAESQTLVSHPQQPTNDRRQYAPAPQPARVGSGAASSRPNTAVRRPAAKPNSPNWLGVKQVGYNEHYIPGDAGIYVEGAPSCGCDSCSGGIGMAYDPGCGFEPSCGFEPSCGFEGAGCTGDACGIGCGCNACVEPGCPPCDPFGWWDWRRTEFFVGVQGFKGPPNFASGNTAGQRDGSASFGFHQGFNMGRPLYFIGCGEFGWQFGLRATQSNLSGAEFTTDERTQLFLTGGVYRRVDCGWQGGVVVDYLSDQWYYDVDLLQIRGELSWKVSPVNEFGFRLTQSTQTSGSVAQLLNDAGVNTTTEAGFLATDQYRFFHRRTMGNGVEVEGNVGFSGSSDVLLGASFDVPMGRCLELRTGFDYLIPDDGSSAGGNQEEGWNLGISFVWTPGGRIAGGRDYYRPLFNVADNGSFMVDRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITH0</accession>
    <name>A0A518ITH0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_23620</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="216" mass="24923" checksum="5F4F908A25FC8E9B" modified="2019-10-16" version="1">MAGYFLYSLDWPSLNSFLESPSEDLAAAMAENVSELLDSYDEQLEDDDEAADWPSDTESLLPILIDRLQRKDWYADLSEIGKNIWERAFVDLCNDDELNPFGFECESDGVYWNIVSEAIAHHDQPKNQLTEKEITHFGARPFRYWHTGRLNWDAWQPMHSMHSPAEVVALAEQFEAAEATLRDSRHPEVDEDYEELMSVLDKLKTNGRVLYVSVDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITN3</accession>
    <name>A0A518ITN3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/beta hydrolase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_24280</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002925">
        <property type="entry name" value="Dienelactn_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01738">
        <property type="entry name" value="DLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022006415" evidence="1">
        <location>
            <begin position="21"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="domain" description="DLH" evidence="2">
        <location>
            <begin position="108"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="379" mass="42647" checksum="7B176CF29B456DC7" modified="2019-10-16" version="1" precursor="true">MMKSVSMLLAFLLVPAFAFAQNRVQPELMEVPEIRSSWDDLTEGIATKEDWIARREVLKQRYLDLLGDQHKPEKPPLDLIVHEDVVVDGLYRRQWISYAVEADERAHAYLGTPLELDGKAPAIVALHGTYQHGSKRAAGLIDNPDKAYLDHLCRRGYVVIAPEHFVSGERTPAAGPYDTAAFYEKHPQWTAVGKFTYEHSIAIDVLQSLPQVDAQRIGALGHSLGGHGTFFLAAYDDRIQASACNCGASFFRHNPNVEGWGRNRWYIYFKPIREGLLKGELPPIDFHEIIALIAPRAFLDVSGLNDGHTPTQKQRLLMLMKIMDVYELNGVPENLGFYVHGRKHSVAHESRQLIYGWMDAHLKPAEATQTHLVVPAAEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITN8</accession>
    <name>A0A518ITN8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Arylsulfatase</fullName>
            <ecNumber evidence="5">3.1.6.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">atsA_20</name>
        <name evidence="5" type="ORF">Mal33_24410</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="PTM">
        <text evidence="1">The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.</text>
    </comment>
    <dbReference type="EC" id="3.1.6.1" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004065">
        <property type="term" value="F:arylsulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021932894" evidence="3">
        <location>
            <begin position="22"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase" evidence="4">
        <location>
            <begin position="25"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="273"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="401"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="273"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="modified residue" description="3-oxoalanine (Cys)" evidence="1">
        <location>
            <position position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR600917-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV56451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="434" mass="48445" checksum="D9665105A33B6642" modified="2019-10-16" version="1" precursor="true">MPTPLRTLPLLLLLLSTPLTADDRPNVLLILADDIGYEALGCYGGLDFQTPRLDAMAAAGLRFSRAYASPVCTPTRVSLHTSLYTTRHQHTIVLPVHRGTKKTVDFQAMPTFAQSIRSTGYATSVTGKWQLATLEYWPDHIRDAGFDSWCVWQIWLQGKKTLRHWNPTLNQDGQVRDDIADRFGPDVLVDYVIDQMRDAQAKEQPFLIVHNEMLPHDPIIATPEDRRLGRPAKLDHMIHYMDHLVGRLLDAVDSMGLRDNTYVLFMGDNGTHEEDFRNPRASEPGQRRHTRHTRAGNVDGGKFKLGDAGTHVPLLVWGPPSVPAGQVCDDLVDVVDLFPTFCELTRTSIPEGLSIDGHSIAAQIHGQPGPTRPWTHQGIGKEENLFDGSWRLFRQSDALKDARSLPAEPNADNQDPQAAAARDRLETAFQTITP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITV6</accession>
    <name>A0A518ITV6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_25130</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="458" mass="47413" checksum="A570ED1E7712867B" modified="2019-10-16" version="1">MATAAALKALFETGDILTEASFVSLIDSMHPDVVTLGTFTGETIPNASTVKEALQSLETALEAFEGGTDGEDGADGASAYELAVGNGFVGDLTAWLASLAGADGEDGTDGTSGIPAVKTANFTAVPGEGPYLVSLSEGDVIATIPVSVGAYSIIVTEPGETIGYYEASGPTPYSVLLHCDDLTDGETTNAAGGTVDVVGGRLTDGAWGNAIVLEPDAGLPVASVDLAPAIYWGSDWTFDGVFFVFGNPVGVAQVKLLEVGSLVLSLSPHDEGFRLRLSHASGVVYGDTLYGDGGWFELHSAKIGVTFDSSTNVVNVYLDGALDLTATIAAFTYTEGITPKISTRGELSTYPALLMEEVRWSQQKEWSSDYTPATSPYIYLEGSSGGGYLDPVPNKLTIAGTTIQLREPGSRVDIQCDGTNTVYQYVGHSLETVAADASVATLIAKLTDAGLILAPVEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUW0</accession>
    <name>A0A518IUW0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_28610</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="456"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="34"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="125"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="468"/>
            <end position="485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV56860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="494" mass="53943" checksum="5453C709CAABBC67" modified="2019-10-16" version="1">MAARDDSVIRGSLITCIIVLVLSLVGNFFMWQWGDAATQEKTKANASLQNAQNQVRTQDSKIQVMERMLGVGQMTDAEFAQMLTSAGGDEKMNLIEQQFAQDMSLMNEDGKKNYHELPSFLMRTIRDKSALLAAAEQQIARLGKEKDAILERETARADKAEKDKEELNTQLQKTMADLAKAREDHNLKQQQMQDLLTKSQQQITAITTSAAREKTQLVKQSTQLQTTIDDQKNTIETLRNDEFETPQGRVVHVMPGGNVVFVNLGSADGLVTGVTFGVIDQDDVRVTNVEPKANLEVTAILGSHLAQARVVHNPDLRNPVLENDKIYTPFWAPGRRVEIALAGLMDLDGDGADDSDRIKAMIKSAGAIVSAQVDARGVETGELTFDTRFLVLGTDPEFSDGDPDAQAGNATALAAVGKLKARAKQLGITTISLNKLLGYLRSLDQDLVIPLGTASRAEDFPPLNTGSHGKRSPGTVSSLFDRNAPNRENSGEDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IV81</accession>
    <name>A0A518IV81_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_29980</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="63" mass="6576" checksum="6569066FB68219BB" modified="2019-10-16" version="1">MPLQARGEVVDPDQMQIVYVSSDVSISLSCVVRIPIPGNRSSTAVAGSENDSNFSAPALQSIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVF5</accession>
    <name>A0A518IVF5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative 2-keto-3-deoxy-galactonate aldolase YagE</fullName>
            <ecNumber evidence="3">4.1.2.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">yagE_2</name>
        <name evidence="3" type="ORF">Mal33_30720</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the DapA family.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.-" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002220">
        <property type="entry name" value="DapA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020625">
        <property type="entry name" value="Schiff_base-form_aldolases_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00701">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001365">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00146">
        <property type="entry name" value="DHPICSNTHASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01130">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00666">
        <property type="entry name" value="DHDPS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0704">Schiff base</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR001365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="303" mass="31781" checksum="4C95C62F71F40D93" modified="2019-10-16" version="1">MIQGIVPPLVTPLSNQDALDGDGLQRLIEHQIDAGVDGLFVLGTTGEGPSLSAALRAEMIAQSGRLIDGRVPMYVGITDTSLVDAVKLAGVAADSGAAAAVAAPPFYFPAGQTELRGWFQQLADALPLPLLLYNMPSCTKIAIELPTIEALIDHSNIVGLKDSSGDLKYLGEAVQLAAARRPDWPVLVGPEALLVEAMGLGAVGGVAGGANLAPKLFTELFAAVQRKDQATIDRLQPIVIQLQTLYGFGKYGSSYLKGLKCALDLRGICSGLLAAPFDVFKPADRQRVATWLDGFADSGFLAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVI7</accession>
    <name>A0A518IVI7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="11">DEAD-box ATP-dependent RNA helicase CshA</fullName>
            <ecNumber evidence="11">3.6.4.13</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">cshA</name>
        <name evidence="11" type="ORF">Mal33_30990</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the DEAD box helicase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="11"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6 11" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 6 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Q_MOTIF" evidence="10">
        <location>
            <begin position="24"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="8">
        <location>
            <begin position="55"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="9">
        <location>
            <begin position="238"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="407"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="5">
        <location>
            <begin position="24"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="407"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QDV57098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="432" mass="48580" checksum="6E123D4BFFEC501D" modified="2019-10-16" version="1">MPSSRERVSILSQNMESNSSEPSLSFSDLDLSPIMLRALKICKFENPSPIQAGLIPLALEGEDVIGQARTGTGKTAAFGIPILEQLDPLEDHCLPQALILVPTRELADQVGQELTRLAKGVPTSIAVLAGGKNLRKQTQQLSDGVQVVVGTPGRVHDHLQRGTFKTHDIWCVVLDEADRMLDIGFRPQIERILRKCPKDRQTLLLSATMAPQVRILAERYMYEPKTVDCSSKDMSVETIEQHYFTVAADKRLELLMRLLDRESPEQVIIFCRTKRGTDKLHRKLSEKYDGVGCMHGDMQQRERDRVIKQLRSKDLKVLVATDVVGRGIDITTISHIINFDVPQDCDDYVHRVGRTGRMGRDGVAFTFIVPGEGDVLTSIEQRINKQLIKDVMDGFDHPVPVNRVAEAEEAAKPKEPSRPKLNRIVRRTRKRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVJ2</accession>
    <name>A0A518IVJ2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Pyrroloquinoline quinone biosynthesis protein PqqE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Mal33_31000</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="6">
        <location>
            <begin position="44"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="404"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV57099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="428" mass="48548" checksum="4358F06E5A390ABE" modified="2019-10-16" version="1">MYLRMAKRLALETDKRLLWKLFWLMGIKGFRSVHKHKRRLKRGEFFPPFLYMSVINSCNLRCQGCWVDVGAKQSRIEVEAANKTITQAKAMGNSFFGILGGEPFMHKDLMEIFRSHPDAYFQVFTNGHFITDEVAAELHRLGNVTPLISVEGSEIISDQRRGREGVLNQTMEGIKTALRHNLMVGVCTSVCQTNIDDLVNDAWVDRLIEMGVMYCWFHVYRPCGPDANPDLSLSSDQQRRVRQFVVDTRATKPIIVVDAYHDGAGNALCPAVTGFTHHIGPWGDIEPCPIIQLAAETIHDDRPLKDKFNESEFLRDFRHMTAQNTRGCVVMERPDILVQIAEKHGARDTTARGTAIEELKAMQPRRSQYVPGNEIPERNLAYRLAKKFCFSDFGAYDQQAFTQAKWTDPGESPAAERSPSQLPVISSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVJ7</accession>
    <name>A0A518IVJ7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Type II secretion system protein D</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">gspD</name>
        <name evidence="4" type="ORF">Mal33_31110</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial secretin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001775">
        <property type="entry name" value="GspD/PilQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032789">
        <property type="entry name" value="T2SS-T3SS_pil_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004846">
        <property type="entry name" value="T2SS/T3SS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00263">
        <property type="entry name" value="Secretin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13629">
        <property type="entry name" value="T2SS-T3SS_pil_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00811">
        <property type="entry name" value="BCTERIALGSPD"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021974735" evidence="2">
        <location>
            <begin position="31"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="domain" description="T2SS-T3SS_pil_N" evidence="3">
        <location>
            <begin position="55"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU004003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV57110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="499" mass="53663" checksum="B2A29443F28FED5F" modified="2019-10-16" version="1" precursor="true">MFKQTMAGVSPSHIMMIVACVVGNSAPALAQSVDAYAASSRSSSSAVTYAVSQPTQRLEMIVNSSRILKLEKVVPRFQVQNEEILIANPVAPNQVQISAQAAGVTQLNLWDVDDTLYTVDVIVTGDARELSTVMQAQFPYASLRITPLPTGAVIDGTVTDTDDIDRVMAVAEQFYPKVVNNIKVVGVQTILLHTKVMEVSRTKLRDLGLDWGTANSTSVFAFGINGTVDALNSSIGSVVATGAPNARVGLLRNGESLDFLIRALQQNNCAKILAEPTVVATHGRPSRFIVGGKFPIIAPDGQGGSTVTFEEFGTSVDFLPFLVGPGRVRLEIRPEVSERDDANGVSLNGFTVPAIRQRYVETAVEMQAGQTYAIAGLLQTRTETISTGPPFLISVPWIGTLFRHVESVENEIELLVTVTPELVDAMDPHEVMPGGPGVDTTVPSDTELYFKGYIEVPRVDSINEEGCMQEPVYEPLAPAMQQTLPVQESSTYTAPVSQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVK5</accession>
    <name>A0A518IVK5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Matrixin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_31160</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002105">
        <property type="entry name" value="Dockerin_1_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036439">
        <property type="entry name" value="Dockerin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045474">
        <property type="entry name" value="GEVED"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006626">
        <property type="entry name" value="PbH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040853">
        <property type="entry name" value="RapA2_cadherin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17803">
        <property type="entry name" value="Cadherin_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00404">
        <property type="entry name" value="Dockerin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20009">
        <property type="entry name" value="GEVED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00710">
        <property type="entry name" value="PbH1"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="5523"/>
            <end position="5597"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin_4" evidence="2">
        <location>
            <begin position="7978"/>
            <end position="8068"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1394"/>
            <end position="1422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="6431"/>
            <end position="6454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="7333"/>
            <end position="7354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1394"/>
            <end position="1412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV57115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="8496" mass="891363" checksum="0D2B9CFBD247BD82" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVL5</accession>
    <name>A0A518IVL5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Mal33_31320</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="UPF0391"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009760">
        <property type="entry name" value="DUF1328"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07043">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036466">
        <property type="entry name" value="UCP036466"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV57131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="55" mass="5628" checksum="CA763432EA3FC7E1" modified="2019-10-16" version="1">MLGWALTFLIIALIAGALGFGVVAGTAASIAKILFVVFLVLFVISLIAGRRGPVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVS8</accession>
    <name>A0A518IVS8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Regulatory protein BlaR1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">blaR1</name>
        <name evidence="3" type="ORF">Mal33_31890</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008756">
        <property type="entry name" value="Peptidase_M56"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05569">
        <property type="entry name" value="Peptidase_M56"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="294"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M56" evidence="2">
        <location>
            <begin position="87"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="369" mass="42280" checksum="C5D0445A1C750DD6" modified="2019-10-16" version="1">MTSFEWLQIVLSYALQITLVLAFSWYLEWTLKSSQAKSRVWTSAFIGLGILLVAGLMLPKLQFFHPWSEIRPSVLLGVIEAEFIIGKTLLVLWVFGAAIVLSRWIFHFVQLHRFIRSTEPLDDERRRRCNTLVESELCTIGKQPVQYRISPEDLGPFCYQFHTPYVFLPESLLTGDTVEMSHVLRHELTHLKTQHPMQLFIQKCLQTMFWFHPLVWASGQRAGLVREFVCDDASTSDPGTTATYLRTLVRVVENRAKPQSGTFAIGRTSSELRQRAMRLAAGNDLKSSVWSHSVSLLPILAALLISQIWLPINPLASSQSMFTRWPSWTAHALHAFDIKVRDYERFEPNVQLHELMERQGNSASALRAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVY8</accession>
    <name>A0A518IVY8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CDP-diacylglycerol--serine O-phosphatidyltransferase</fullName>
            <ecNumber evidence="4">2.7.8.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Phosphatidylserine synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Mal33_32580</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a CDP-1,2-diacyl-sn-glycerol + L-serine = a 1,2-diacyl-sn-glycero-3-phospho-L-serine + CMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16913"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57262"/>
            <dbReference type="ChEBI" id="CHEBI:58332"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="EC" id="2.7.8.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the CDP-alcohol phosphatidyltransferase class-I family.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.8" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003882">
        <property type="term" value="F:CDP-diacylglycerol-serine O-phosphatidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004533">
        <property type="entry name" value="CDP-diaglyc--ser_O-PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000462">
        <property type="entry name" value="CDP-OH_P_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043130">
        <property type="entry name" value="CDP-OH_PTrfase_TM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01066">
        <property type="entry name" value="CDP-OH_P_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00473">
        <property type="entry name" value="pssA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00379">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="56"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="91"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="152"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="224"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="268"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00032361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV57254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="315" mass="34748" checksum="203DF85FEEB507AC" modified="2019-10-16" version="1">MRRGTWFAVSITIELETHDGQPSARDLPTILQFPSGNTKYMSYRPARKRRRPRMSLSFLPTMLTLGNGACGMASIAMAYNAELNWSTENKLFAAGCLIFAGMLFDAFDGWAARATKQTSEFGAQLDSLCDAITFGVAPAVLVWQYSNVLPLRVIYPIGVLFTLCTILRLARFNVETPSDDAEDHAYFEGLPSPAAAGTIATFAIATPELSAMQTSVADPRAQELAATVLASCQYLLPALAVILAYLMVSRFRYEHFVPKWLGGHWSPFQIGLALFAIMTVVVVKELALPLMFCYYAFESPIRNWMRLPESARASG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IW20</accession>
    <name>A0A518IW20_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">50S ribosomal protein L29</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 6" type="primary">rpmC</name>
        <name evidence="6" type="ORF">Mal33_32830</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uL29 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00374">
        <property type="entry name" value="Ribosomal_L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001854">
        <property type="entry name" value="Ribosomal_L29/L35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036049">
        <property type="entry name" value="Ribosomal_L29/L35_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00831">
        <property type="entry name" value="Ribosomal_L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46561">
        <property type="entry name" value="SSF46561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00012">
        <property type="entry name" value="L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV57279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="73" mass="8337" checksum="2F00AFC42B07C7C3" modified="2019-10-16" version="1">MKITELREMSDEQLQLTLKETAEKLFHLKFQAQTERLDAPSEIRKSRRLIARIKTIQTQRAPQAAAEGEAAAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWB2</accession>
    <name>A0A518IWB2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">50S ribosomal protein L11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6 11" type="primary">rplK</name>
        <name evidence="11" type="ORF">Mal33_33850</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 8">Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.</text>
    </comment>
    <comment type="PTM">
        <text evidence="6 8">One or more lysine residues are methylated.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the universal ribosomal protein uL11 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00349">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.250">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00736">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000911">
        <property type="entry name" value="Ribosomal_L11/L12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036796">
        <property type="entry name" value="Ribosomal_L11/L12_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006519">
        <property type="entry name" value="Ribosomal_L11_bac-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020783">
        <property type="entry name" value="Ribosomal_L11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036769">
        <property type="entry name" value="Ribosomal_L11_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020785">
        <property type="entry name" value="Ribosomal_L11_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020784">
        <property type="entry name" value="Ribosomal_L11_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11661">
        <property type="entry name" value="PTHR11661"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00298">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03946">
        <property type="entry name" value="Ribosomal_L11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00649">
        <property type="entry name" value="RL11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46906">
        <property type="entry name" value="SSF46906"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54747">
        <property type="entry name" value="SSF54747"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01632">
        <property type="entry name" value="L11_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00359">
        <property type="entry name" value="RIBOSOMAL_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0488">Methylation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 6 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 6 8" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L11_N" evidence="10">
        <location>
            <begin position="10"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal_L11" evidence="9">
        <location>
            <begin position="71"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QDV57380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="141" mass="14882" checksum="11EEBE249D023301" modified="2019-10-16" version="1">MAKQLVGQAKFQVPGGQATPAPPVGTSLGKFGVNLGQFVQAFNDRTKEYAGTPIPVIVSVYNDRSFDFVTKSPPAASLLKQTAGIAKGSGVPHKDKVASVSRAQCQEIAEKKMADLNARDIEHAIRMIEGTARSMGIDVVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWH2</accession>
    <name>A0A518IWH2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Mal33_34370</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011429">
        <property type="entry name" value="Cyt_c_Planctomycete-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011478">
        <property type="entry name" value="DUF1585"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013036">
        <property type="entry name" value="DUF1587"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013039">
        <property type="entry name" value="DUF1588"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013042">
        <property type="entry name" value="DUF1592"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013043">
        <property type="entry name" value="DUF1595"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07635">
        <property type="entry name" value="PSCyt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07627">
        <property type="entry name" value="PSCyt3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07624">
        <property type="entry name" value="PSD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07626">
        <property type="entry name" value="PSD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07631">
        <property type="entry name" value="PSD4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07637">
        <property type="entry name" value="PSD5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021887674" evidence="2">
        <location>
            <begin position="18"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="domain" description="PSCyt1" evidence="7">
        <location>
            <begin position="39"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="PSD3" evidence="4">
        <location>
            <begin position="123"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="PSD5" evidence="8">
        <location>
            <begin position="405"/>
            <end position="465"/>
        </location>
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                <person name="Pinto D."/>
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                <person name="Rast P."/>
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                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2090.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
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        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82714">
        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="356"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="381"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="413"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="452"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="484"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="553"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="884"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="912"/>
            <end position="934"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="940"/>
            <end position="964"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="985"/>
            <end position="1005"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1011"/>
            <end position="1033"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1072" mass="115425" checksum="364B3ECAA94F6DD7" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWZ9</accession>
    <name>A0A518IWZ9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Radical SAM superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Mal33_36240</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039661">
        <property type="entry name" value="ELP3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005909">
        <property type="entry name" value="RaSEA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11135">
        <property type="entry name" value="PTHR11135"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004954">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Elp3" evidence="7">
        <location>
            <begin position="58"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV57611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="334" mass="37417" checksum="479539083F84F280" modified="2019-10-16" version="1">MIDGDRPIEDPAPRELAEAINDRQILAARGPKNRVDPRRAYQAFVEPEFSVDRIVEDVATIFLTNRECPFRCLMCDLWKNTTDDRVPPGSIVQQIEHALASLPAAPRIKLYNSGNFFDAAAVPREDLPRIAKIVGGHRSVIIENHPKLCDDRALRFRDQCGTDLEVAIGLETSHPPTLQRLNKQITRDDFARAAEFLTSNGIRVRAFILLRPPWTTEGEGIERAIESVRFAFNSGVDCCAVIPTRGGNGIMERLQREGLFTPPRLTSLETVLDETLRWKSGIVLADLWDAEQFASCTVCARQRIDRLQRMNMTQTVPPPVTCQACDSEGGGRLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IX12</accession>
    <name>A0A518IX12_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Chromosome partition protein Smc</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">smc_3</name>
        <name evidence="3" type="synonym">smc</name>
        <name evidence="6" type="ORF">Mal33_36370</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Required for chromosome condensation and partitioning.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="3">Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SMC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030261">
        <property type="term" value="P:chromosome condensation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007062">
        <property type="term" value="P:sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01894">
        <property type="entry name" value="Smc_prok"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003395">
        <property type="entry name" value="RecF/RecN/SMC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024704">
        <property type="entry name" value="SMC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010935">
        <property type="entry name" value="SMC_hinge"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036277">
        <property type="entry name" value="SMC_hinge_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011890">
        <property type="entry name" value="SMC_prok"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06470">
        <property type="entry name" value="SMC_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02463">
        <property type="entry name" value="SMC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005719">
        <property type="entry name" value="SMC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00968">
        <property type="entry name" value="SMC_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75553">
        <property type="entry name" value="SSF75553"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02168">
        <property type="entry name" value="SMC_prok_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SMC hinge" evidence="5">
        <location>
            <begin position="525"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="299"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="240"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="387"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="773"/>
            <end position="870"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="906"/>
            <end position="933"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="985"/>
            <end position="1033"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="31"/>
            <end position="38"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV57624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1206" mass="133705" checksum="B920A8B98553FAFD" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IX69</accession>
    <name>A0A518IX69_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Protein MtfA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">mtfA</name>
        <name evidence="1" type="ORF">Mal33_36910</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20169">
        <property type="entry name" value="Peptidase_M90_mtfA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010384">
        <property type="entry name" value="MtfA_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042252">
        <property type="entry name" value="MtfA_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30164">
        <property type="entry name" value="PTHR30164"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06167">
        <property type="entry name" value="Peptidase_M90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="259" mass="30153" checksum="0AFE2896504C55E2" modified="2019-10-16" version="1">MIFSWIAQRRRDRIRRQPMRSDWSQIIDRNVAYVHRLNRDERAKLESDALVFIAEKNWEGCQGLTMNDEIRVTIAAQISLLCLGFTDQFFDMVQSILVYPDVYTGKSHTSLGSGVLMEGVSHREGEAWYRGPVILSWADVLEDGDRDNDGNNLVLHEFAHQLDMLNGRVVDGTPPMETQAQFDRWQTLIEREYEQLVSDCQYGRSHVINSYGAEHISEFFAVATETFFERPLSFRARHPELYEIFSQYYRQNPAARFDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IX81</accession>
    <name>A0A518IX81_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Aerobic glycerol-3-phosphate dehydrogenase</fullName>
            <ecNumber evidence="5">1.1.5.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">glpD</name>
        <name evidence="5" type="ORF">Mal33_37040</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.5.3" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009331">
        <property type="term" value="C:glycerol-3-phosphate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052591">
        <property type="term" value="F:sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006072">
        <property type="term" value="P:glycerol-3-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000447">
        <property type="entry name" value="G3P_DH_FAD-dep"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11985">
        <property type="entry name" value="PTHR11985"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01001">
        <property type="entry name" value="FADG3PDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DAO" evidence="4">
        <location>
            <begin position="5"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV57691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="519" mass="57123" checksum="4DC72290DB562C42" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXD7</accession>
    <name>A0A518IXD7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">N-acetylneuraminate epimerase</fullName>
            <ecNumber evidence="2">5.1.3.24</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">nanM_2</name>
        <name evidence="2" type="ORF">Mal33_37670</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="5.1.3.24" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006652">
        <property type="entry name" value="Kelch_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01344">
        <property type="entry name" value="Kelch_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00612">
        <property type="entry name" value="Kelch"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="SSF117281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022148471" evidence="1">
        <location>
            <begin position="26"/>
            <end position="550"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="550" mass="59669" checksum="09C81F4A484386A9" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXI9</accession>
    <name>A0A518IXI9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cold shock protein CspB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">cspB</name>
        <name evidence="4" type="ORF">Mal33_38160</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04458">
        <property type="entry name" value="CSP_CDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012156">
        <property type="entry name" value="Cold_shock_CspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011129">
        <property type="entry name" value="CSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019844">
        <property type="entry name" value="CSD_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002059">
        <property type="entry name" value="CSP_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00313">
        <property type="entry name" value="CSD"/>
        <property type="match status" value="1"/>
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</entry>
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                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
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                <person name="Peeters S.H."/>
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            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="565" mass="60487" checksum="F7A7BDFCAFC144F5" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
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    <sequence length="450" mass="48680" checksum="85C151409A84D8A3" modified="2019-10-16" version="1">MLSIHSAAKKATRLCDGISRREVLKIGALGMGGLTLPQLLQAEAAAGIRGSQKSIIMIYMVGAPPHQDMYDLKMDAPSEIRGESRPMATNVPGIQISELMPGIAKIMDKCVPLRSVYGSPNGAHDSFICYTGRPTQNQPPGGWPSIGSTISQLQGPADPSVPPFVGLSPDAGHPPYGSPGLPGFLGVGNAAFRPSGPAEKSMVLSDITLDRMKDRKQLLQSFDRFRRDADASRTMEGIDQMYGQAMDILSSGRLADALDLSKEDPATRERYGKGSPAKYGDGAPRNLEHFLMARRLVEAGARVVTLNFGRWDFHSRNFSELRDTHLPWFDQGLSALIEDLHDRGMADDVSVVAWGEFGRTPKINKDGGRDHWPRVGGGLLAGGGMKTGQVIGSTDRLGGEIDSRPIHFGEVHATLYQNMGINPHSTMVRDFAGRPHFLVDNHPAMPELIG</sequence>
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    <name>A0A518IXQ0_9BACT</name>
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
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                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
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                <person name="Overmann J."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="7 8">Mal33</strain>
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    <sequence length="986" mass="108741" checksum="24BF763242CBCEA7" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
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                <person name="Devos D.P."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">Mal33</strain>
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    </reference>
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        </source>
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</entry>
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
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                <person name="Overmann J."/>
                <person name="Amann R."/>
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                <person name="Ovreas L."/>
                <person name="Rohde M."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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            <begin position="4"/>
            <end position="261"/>
        </location>
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    </evidence>
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        </source>
    </evidence>
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            <dbReference type="EMBL" id="QDV58006.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="531" mass="57460" checksum="3B79C3F58E3EC417" modified="2019-10-16" version="1"> </sequence>
</entry>
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5 6">Mal33</strain>
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    </dbReference>
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        <location>
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        <location>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="QDV58005.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="744" mass="80241" checksum="7C04F4871149FD7A" modified="2019-10-16" version="1"> </sequence>
</entry>
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    <accession>A0A518IY84</accession>
    <name>A0A518IY84_9BACT</name>
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            <fullName evidence="2">Bifunctional protein PaaZ</fullName>
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    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
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                <person name="Kohn T."/>
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                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
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                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
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                <person name="Lage O.M."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">Mal33</strain>
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    <feature type="domain" description="MaoC-like" evidence="1">
        <location>
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            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="164" mass="18617" checksum="2DCF7323F2CA8670" modified="2019-10-16" version="1">MIEKLYLEDLCKGDHWVSPSQTITREHVIRFAELTGDHDPLHVDEEFASKSAFRQPIAHGLLGLSIMAGLSSKHPMVHTIAFTELDDWQFKHPIFFGDTVHVETEIVAIQPYGRRAGKVTWFRQLVNQSGQVVQQGSLDTIVAARQPRKSKRTDRTTTKIQESV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
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    <name>A0A518IY88_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_40740</name>
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        <name type="scientific">Rosistilla oblonga</name>
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    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="QDV58057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="entry name" value="CHP03009_planctomycetes"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03009">
        <property type="entry name" value="plancto_dom_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022173606" evidence="2">
        <location>
            <begin position="22"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="295"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="320" mass="36479" checksum="CF009235DF26228A" modified="2019-10-16" version="1" precursor="true">MMRLIRSIGLLGLLFAATCPAQQPATGQPARPGTSNAAAGAPAAQPFPALTAEQQNRLDQLLKAWESSSNSTKRLSASFKRWQFRPLQAPKEIHASWARGEVKYQAPAQGMYRVEEMLFFTGFDEQKAPIYKKQANQPGDWWVCTGKELLEFDRANKKCEILELPPEMQGTQIVSSPLPFVFNLNAQEMKDRYWLQELPPKEQGEYWLEAWPKHQKDRAEFLKVMIIIDAKQFLPKALVLFPPNFDQRNNPERDVYEFTDVQRNGNLFSKAMEGIFGQNFIDVTPPSDWKIIRNKFNPGPPPKMAQEQGNMQPGQAPQSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IY89</accession>
    <name>A0A518IY89_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Outer membrane biogenesis protein BamB</fullName>
        </submittedName>
    </protein>
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        <name evidence="3" type="ORF">Mal33_40650</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="PQQ_beta_propeller_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002372">
        <property type="entry name" value="PQQ_repeat"/>
    </dbReference>
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        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01011">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PQQ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00564">
        <property type="entry name" value="PQQ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022033315" evidence="2">
        <location>
            <begin position="25"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="445"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="445"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="518" mass="55492" checksum="466AAAE4F5E2313B" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYD8</accession>
    <name>A0A518IYD8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Ethanolamine utilization protein EutN</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">eutN</name>
        <name evidence="1" type="ORF">Mal33_41220</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="C:bacterial microcompartment"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004992">
        <property type="entry name" value="EutN_CcmL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036677">
        <property type="entry name" value="EutN_CcmL_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36539">
        <property type="entry name" value="PTHR36539"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03319">
        <property type="entry name" value="EutN_CcmL"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF159133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51932">
        <property type="entry name" value="BMV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="87" mass="9272" checksum="ED59EFFAFE878F9B" modified="2019-10-16" version="1">MQTAKVLGTTRATIKHASFVGQKLLIVQPLMADGSADGPPLLTLDGWGASRGDTVLLTSDSSCMEDLIGKDKNTPARWTTMGIIDQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYQ2</accession>
    <name>A0A518IYQ2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative peptidase</fullName>
            <ecNumber evidence="6">3.4.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Mal33_42240</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase M24B family.</text>
    </comment>
    <dbReference type="EC" id="3.4.-.-" evidence="6"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029149">
        <property type="entry name" value="Creatin/AminoP/Spt16_NTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000587">
        <property type="entry name" value="Creatinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001131">
        <property type="entry name" value="Peptidase_M24B_aminopep-P_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01321">
        <property type="entry name" value="Creatinase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53092">
        <property type="entry name" value="SSF53092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="SSF55920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00491">
        <property type="entry name" value="PROLINE_PEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Creatinase_N" evidence="5">
        <location>
            <begin position="4"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M24" evidence="4">
        <location>
            <begin position="139"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV58207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="361" mass="38933" checksum="B0707BD5E93160BF" modified="2019-10-16" version="1">MSTRIEKLRSLLVDEAVDCLLVTGETDVRYLSGFTGDSSYLLVSADRCAILTDRRYETQIEAECGGIESFVRGPERTMTQLVAEAVDDFSAATIGLDANDVSWALLEGLRSALPQQTFAATNGLVLKLRQIKEPEEIETIRRAVRIAEQTFQAIRATLRRGQTELEIAHDVEKWIRYFGGEGCGFATIAAIGPNAALPHAQPGERRVGDDPALLLDWGARYNGYTSDLTRMTAIGAPSPEMAEIYPVVLEAQLAAIAAIRPGAELKAVDAAARNVIRDAGFGDYFGHGLGHGIGLQVHESPRMSAITEGTLQAGMVVTVEPGIYLPGKLGVRIEDDVLVTENGHEVLSSLPKGLDDCTVIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYX6</accession>
    <name>A0A518IYX6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Abasic site processing protein</fullName>
            <ecNumber evidence="7">3.4.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Mal33_43100</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the SOS response-associated peptidase family.</text>
    </comment>
    <dbReference type="EC" id="3.4.-.-" evidence="7"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006974">
        <property type="term" value="P:cellular response to DNA damage stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018142">
        <property type="term" value="P:protein-DNA covalent cross-linking"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1680.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003738">
        <property type="entry name" value="SRAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036590">
        <property type="entry name" value="SRAP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13604">
        <property type="entry name" value="PTHR13604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02586">
        <property type="entry name" value="SRAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143081">
        <property type="entry name" value="SSF143081"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0190">Covalent protein-DNA linkage</keyword>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 7" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV58292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="211" mass="24213" checksum="6A76F26B7E60EB56" modified="2019-10-16" version="1">MCHRFHIKTGAQAIADMLGATNQCEEGAFQPELFPLATVPVIRADASSSLELVACHWSLLPRTWKPSAKYPTWKSFVRKYPTFNARSESIDEKLSFRQSFADRRALIPATAFFEHGFYFGLEGVETFWFAGLWDRCTVAEETIETCTIVTTQANRLVGRHHPRNRMPVILADEDARKRWMDPAITRRGELQDLFRPLADDRMTHWPAEPAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ11</accession>
    <name>A0A518IZ11_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulatory protein TdiR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">tdiR_2</name>
        <name evidence="5" type="ORF">Mal33_43380</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="24"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="154"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV58320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="229" mass="25820" checksum="B6B8820C419D6017" modified="2019-10-16" version="1">MNDYSSEADVDRSTKPILRIDSPTVFYVDVDEGVRDSLDQLLEAIGLPLRTFPSGEAFLRAYDGSPGCLITDIRTPSGLAGIELQSRLARSPISLPLIITASVEDASLAVRAMQNRAVTLIEKPYRDHELIEAIQSSLRIDRMHRQQDMRTREVFTRLATLSPNETEVLELIIEGVTNKVIANRLDVSIRTIENRRKRIYEKMRTESVAVLVRMVVEARIRTGQAVERS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ43</accession>
    <name>A0A518IZ43_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative sugar transferase EpsL</fullName>
            <ecNumber evidence="4">2.-.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">epsL_2</name>
        <name evidence="4" type="ORF">Mal33_43730</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial sugar transferase family.</text>
    </comment>
    <dbReference type="EC" id="2.-.-.-" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003362">
        <property type="entry name" value="Bact_transf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02397">
        <property type="entry name" value="Bac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Bac_transf" evidence="3">
        <location>
            <begin position="160"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="129"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV58355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="353" mass="40146" checksum="2AE7BF267CC1C81C" modified="2019-10-16" version="1">MPSLVGGYRASRALTPLLLSERQLSRELNRERLRADRRQIPFCLIDVVLAPENRRPRDVKRLARLLHRRLRTTDTLGHRGRVTVGVLLTDTPEQGGRIVVDELQELLLDARLDCDLELYAYDPDAWQQQQLFDPPDDHQPPSGHLTPPQPQAARRRRVAKRLVDVVGSSLGLLFASIPIALACVAIRCTSAGPAIFRQVREGADGKPFTIYKLRTMRCDAEHHQANLRQLSERDGPAFKIKDDPRITSVGKWLRATCIDELPQLVNVLIGQMSLVGPRPLPWAESRAVATWQRRRLDVKPGITGSWQTSKHESITFDDWMRMDLRYIDRGSNWLDMKLIAKTMIVPVKARGNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ56</accession>
    <name>A0A518IZ56_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_43860</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58368.1"/>
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            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
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                <person name="Heuer A."/>
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                <person name="Oberbeckmann S."/>
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                <person name="Jeske O."/>
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                <person name="Storesund J.E."/>
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                <person name="Lage O.M."/>
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</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 4">Mal33</strain>
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    </evidence>
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        </source>
    </evidence>
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</entry>
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            <authorList>
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                <person name="Heuer A."/>
                <person name="Rast P."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </dbReference>
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        </location>
    </feature>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="QDV58517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="275" mass="31718" checksum="27CD05F964FC0C1E" modified="2019-10-16" version="1">MEGFCNGLHKSPHKGFSVEFKEHRQYVHGDEIRTIDWKLFGKTDRLYIREYEEETNLRCNILLDKSGSMGYCGSRAGGVSKHDYAVRLAACLGHLMLAQQDAVGLIHFDDAVRRIIPPRSKPTHLTAIVNELSGLKAERETELSSVFHQLVPKIPRRGLLVIISDLFGNIEELMKALAHFRHAKHEIVIFQIWDPDELDFPFKQWTQFQSLEQKSHRRLIDPAHLRKAYLKNLATFREALTAGCHRNRIDLVPVVTDRPYAEALASYLATRRRLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZW7</accession>
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        <submittedName>
            <fullName evidence="6">Putative ABC transporter ATP-binding protein</fullName>
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    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
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                <person name="Storesund J.E."/>
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                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030296">
        <property type="entry name" value="MlaF/Mkl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43023:SF6">
        <property type="entry name" value="PTHR43023:SF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="21"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="271"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="271"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="288"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="53"/>
            <end position="60"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV58637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="304" mass="34414" checksum="1C19A9480332EDAF" modified="2019-10-16" version="1">MDSDTQTIELPEEPPARQYLLDAQDLHVELSGHHILKRINLKIPRGETLALIGESGCGKTVLMKTLIGLVRPTRGIVRFDGQDIAAMKPAEAVNFRKKIGFVFQNAALFDSMTVGQNVAFPLRQHNVVDADQVEPLVLRALGEVGLPDDIVRRRPAQLSGGMRKRVGIARALILQPDLVLYDEPTTGLDPIVSDVINELMLGVRRKYPVTSIIVTHDMNTARKVADRVIMLYPRRRLKDHESQVLFDGPPTSLENFEDRRVRQFVRGEAGERLMEMRQQSEELDEQLEHDRFENEDDDESPLDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0E7</accession>
    <name>A0A518J0E7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">tRNA dimethylallyltransferase</fullName>
            <ecNumber evidence="5">2.5.1.75</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Dimethylallyl diphosphate:tRNA dimethylallyltransferase</fullName>
            <shortName evidence="5">DMAPP:tRNA dimethylallyltransferase</shortName>
            <shortName evidence="5">DMATase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Isopentenyl-diphosphate:tRNA isopentenyltransferase</fullName>
            <shortName evidence="5">IPP transferase</shortName>
            <shortName evidence="5">IPPT</shortName>
            <shortName evidence="5">IPTase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 9" type="primary">miaA</name>
        <name evidence="9" type="ORF">Mal33_48340</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 5 7">Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5 6">
            <text>adenosine(37) in tRNA + dimethylallyl diphosphate = diphosphate + N(6)-dimethylallyladenosine(37) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:26482"/>
            <dbReference type="Rhea" id="RHEA-COMP:10162"/>
            <dbReference type="Rhea" id="RHEA-COMP:10375"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57623"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74415"/>
            <dbReference type="EC" id="2.5.1.75"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 5 8">Belongs to the IPP transferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.75" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052381">
        <property type="term" value="F:tRNA dimethylallyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00185">
        <property type="entry name" value="IPP_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039657">
        <property type="entry name" value="Dimethylallyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018022">
        <property type="entry name" value="IPT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11088">
        <property type="entry name" value="PTHR11088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00174">
        <property type="entry name" value="miaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 6" id="KW-0819">tRNA processing</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="21"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Interaction with substrate tRNA" evidence="5">
        <location>
            <begin position="44"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="19"/>
            <end position="26"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Interaction with substrate tRNA" evidence="5">
        <location>
            <position position="110"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with substrate tRNA" evidence="5">
        <location>
            <position position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV58809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="323" mass="35883" checksum="16373C19EA3B0944" modified="2019-10-16" version="1">MGDSTTFPSLTHRACFLTGPTASGKSTVADSLAAKLELEILSLDSMTVYRRMDLGTAKPSAAQQQQTVHHLLDQVDPDAEFSAAQYLTAAHAAVDQIAAAGKLPLFVGGTPLYLKACLRGFDAGPPADWEFRKSIEADLKEHGVDALRKRLEQVDPLSAHQLHPNDTRRMIRALEVAMLTGQPISHRQVQFEASHSADQANVYALHWPRNLLHQRIDRRVDQMFADGLVDEVAAIRRDFPTISRTAAQAVGYKEVFDLLDGTTDLADTIEQVKAHTRQLARRQETWLRSMSEVEFIEMNEERTHDDIAAEIIEKSQSRPDPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0G4</accession>
    <name>A0A518J0G4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_48550</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022190293" evidence="2">
        <location>
            <begin position="24"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="197"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="226" mass="24247" checksum="02D5CAFCBAD3409D" modified="2019-10-16" version="1" precursor="true">MVAGLACSLAASMLVVSTGGCTAFAGLSNSLDYNECCDEFVLGYRNSAWSARAWHERKHCFKNEDHRYHFRDGFRQGYEDVANGGNGCTPAFPPRSYWSWKFQSPEGQQRVNAWFAGYPHGARAAEEDGLGNYGQIQMSAQMAAACQSCGMGEPAYVDSTKPAEAAEPTPSQVTGYEGLLGEGETIVGDVQLGLERPANQPAPAVRTASPRIGSGIGGPIQRPQPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0H8</accession>
    <name>A0A518J0H8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Sensor histidine kinase RegB</fullName>
            <ecNumber evidence="5">2.7.13.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">regB</name>
        <name evidence="5" type="ORF">Mal33_48300</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
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            <strain evidence="5 6">Mal33</strain>
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    </evidence>
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    </evidence>
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    </evidence>
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        <source>
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    </evidence>
    <sequence length="463" mass="50875" checksum="1E2A958B40CC90C3" modified="2019-10-16" version="1">MPFAALSRLFHPSVMLRAPLGTSTWLLQLRWFAVVGQLVTISAVGRFFPVDLPLEPLFAFIGFTAATNLAYTIWLGTREPAEPQASDDALYRTEVASLLMTLDLLTLAAMLYFSGGIDNPFVFFFFVNLAVAGVVLRPVWAWILTSMSIACFAVLTYFRTPIELLSIDSHAAGYRMREHGMLIAFSTCAAVVTYFVSRVAEELTVRQTQLRTALQQQSRSQRLEALTTLAAGAAHELASPLSTIAVVVHEMQRHAAEADVPDAVRQDLSLIDSEVNHCKAILSRMRNAAGDQAAEHWDRITLVDLVDAIVEGIRDPHRVEISDDVDRFDDYTLWIPMEAVAQAIRNLIGNALDASPAEASVAVEVSVTEDHFTMEVIDSGEGMPEEVAQRAVEPFFTTKQPGSGMGLGLFLTRNVITRLGGTLEFDTKLGRGTRAIVRMPRRQQLAAENLPDGGSQMTHNGLE</sequence>
</entry>
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    <accession>A0A518J0I8</accession>
    <name>A0A518J0I8_9BACT</name>
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
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                <person name="Spormann A.M."/>
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                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
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        </location>
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        <source>
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    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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        <source>
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            <dbReference type="Pfam" id="PF07635"/>
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    </evidence>
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            <dbReference type="Pfam" id="PF08305"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="QDV58848.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1013" mass="112120" checksum="6996CDDFFD6AD41A" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0M0</accession>
    <name>A0A518J0M0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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    </gene>
    <organism evidence="2 3">
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        <dbReference type="NCBI Taxonomy" id="2527990"/>
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    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
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                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
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                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
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                <person name="Jeske O."/>
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                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
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                <person name="Bruemmer F."/>
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                <person name="Spormann A.M."/>
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                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
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                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
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    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022134845" evidence="1">
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            <begin position="22"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="323" mass="35576" checksum="3FD8DA0E50D0BC20" modified="2019-10-16" version="1" precursor="true">MKSILQLAGLCLLSGAATAHAQTLLSIPFDSDEDLQYFVAPVDELAVEPAFDNQRCLVIGGDVDARALKPIAVQALKKYKLTLRAAVDDSDTVETNDRLPEILAKNGGKSFAACQLTFFDKDGEETSFLLYGRIRMRAHPISIISGQLHEFVSVFYAPPEAETLQLKLLPRGRKVWIDEIVVERETLEGTENGNPDFRYGKFNLSGWDPGSEGRLYVRSDGTTVLKCGTSGGSSFFAVDDQARYSFHCKGKGYSKTAGKVTVSFYDMTGKDLGYTHLFWNRDMEEGATKNGIKPPPGAKLAMLKSSRLILEKVMVSRDRPATD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0W8</accession>
    <name>A0A518J0W8_9BACT</name>
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        <submittedName>
            <fullName evidence="3">Na(+)/H(+) antiporter subunit G</fullName>
        </submittedName>
    </protein>
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        <name evidence="3" type="primary">mrpG_2</name>
        <name evidence="3" type="ORF">Mal33_49700</name>
    </gene>
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        <lineage>
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    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Boedeker C."/>
                <person name="Pinto D."/>
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                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005451">
        <property type="term" value="F:monovalent cation:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098662">
        <property type="term" value="P:inorganic cation transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005133">
        <property type="entry name" value="PhaG_MnhG_YufB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34703">
        <property type="entry name" value="PTHR34703"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03334">
        <property type="entry name" value="PhaG_MnhG_YufB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01300">
        <property type="entry name" value="CPA3_mnhG_phaG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="37"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="63"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="115" mass="12117" checksum="90DF8C0C646D211C" modified="2019-10-16" version="1">MNDILTIFLLITGTGFALLASIAIVRMPDLYTRMHGATKCATLGVGCTILAAAVRFANMETATVAVLIIGFLFLTAPVAAHMIGQAAHRQQVPKWSGTVVDESPAADANEETRSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J150</accession>
    <name>A0A518J150_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_50600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="143" mass="16417" checksum="C75F1C8A4D42AE11" modified="2019-10-16" version="1">MSVHTWHNGRSGGNPNRQHPGNQPEHKDHERSNAYDALPTVKHEVTEWRNETKDLQRHFRNAIDHLAARNIGFVQDGQLRNLYVEAGDDKSTPAETKPRKCSKDERHDAYWKQHAMSCRHPIVANFGRVTARFSGPGELIVHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J195</accession>
    <name>A0A518J195_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase-like domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_51400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="49"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="169" mass="18373" checksum="D14658265F759E50" modified="2019-10-16" version="1">MRCYGAAVVAVPPLGEPLAAPRILLPFKCTRTHFLNSQFSRKFKMETNPVGWFEIYVQDICRATKFYETVLGIKLNKLEAPVPGMEMMVFPLDMERPGASGALTKMDGFESGSGGTIVYFGCEDCAVEASRVGAAGGKIKSPKMSIEEFGAFALAIDTEGNMFGLHSMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1F9</accession>
    <name>A0A518J1F9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Soj-like protein</fullName>
            <ecNumber evidence="2">3.6.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_52040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.6.-.-" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025669">
        <property type="entry name" value="AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13614">
        <property type="entry name" value="AAA_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_31" evidence="1">
        <location>
            <begin position="1"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="269" mass="29068" checksum="E62A2B4AE28D7386" modified="2019-10-16" version="1">MRTIAIINQKGGVGKTTTAVNLSAALAEAGKRVCVVDLDPQAHASLHLGISVLDGKPSTYEVLCGEISLAHSRQWVSDNLAVVPAHLDLAAAEMELSGEVGREMILRDKVAEDDEQFDYMILDCPPSLGVLTLNALVAVEEVFLPLQPHFLALHGLSKLLRTVEIVSMRLNESLRMSGVVLCMYDSTTRLAAEVSSDVEQFFNTSQGGRHILDGAKFFDTRIRRNIRLAEAPSFGQSILEYASASNGAEDYRSLASEVQAQMARVAAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1H4</accession>
    <name>A0A518J1H4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_51960</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="69" mass="7874" checksum="B08A7C10203B61BA" modified="2019-10-16" version="1">MRRSILEAVQDGDWAFEPLPCDEEQYEPTAALPGSAEKLDVLQCRVQQGLPLWHPSDRRFYREEAGSIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1Q5</accession>
    <name>A0A518J1Q5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Tad domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_52970</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028087">
        <property type="entry name" value="Tad_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13400">
        <property type="entry name" value="Tad"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tad" evidence="1">
        <location>
            <begin position="11"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="419" mass="46477" checksum="80799FC0341810D1" modified="2019-10-16" version="1">MNRRKQRERRGQSLMLMFLVILALVGVLALTFDFGFVVLSRRMMQTAVNTGALEGARDRAGLGREDARNVIRNVFDDDLDPTANTTSLGAGPDQSLVQRDALQRPRFGDGSRVEEWFPERHQFIYRPAPQLNDANELHGDFVRGYYCDESTSSKVNDGESNDDVCEPCRDESMSRSVIHRESNDYVRDDFDRDDCDDCDDSEPNAFLARIRRTPQRDGIANPLDRIAGVSSSGSGSPLMIGHLMPIRPNSADSYDIRRDGVAIRATAIAVTQPIVYVGKATGDDFLQLLDYAYYVECPKWVLLDNPQHRLGASMPPPDDPTHQNASAPTTPGYAAIVGNITGECGGSQVQKEYYVIGFCQRLGSRQLRANASPRLQDAWPELGKLSPATRSAILKRNRNLDLLGTFESAGQPALVRTLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1U1</accession>
    <name>A0A518J1U1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ribonuclease Z</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_53260</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12706">
        <property type="entry name" value="Lactamase_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="54"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="279" mass="32216" checksum="86D53CEE8AC9A3FB" modified="2019-10-16" version="1">MFENIPLRKCQHAGLTIEGYSRAAVQTCWRIPELKCGFDLGVQPWDFMGTPTWFVSHTHLDHIAALAVYVSRRRMMKMDPPVIYLPANSIDHCLAMLRSFTRLDKGAMPCELLPAEPGDEIELSRELVVNVFPTRHTITSVGFMVSERRKKLKEEFQGLQGTEIRDLRMKGVEVSHETRMPILAYTGDTQPRGLDDNPEVFDCKILIAEMTFIAPDHRKEKIHKHGHMHLDDWVARKDRFNNELIIASHFSTRYSDQQIRRMVEKKLPGLLGGRLNLWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1U3</accession>
    <name>A0A518J1U3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_53340</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="131" mass="14498" checksum="4117299F69EBA1FF" modified="2019-10-16" version="1">MRDDHDFGDAERRDSPAIEAVIRAAGDYVVVSDDLRPRTIEAAIERQGLAVTRRRVRWAALGAALFLAVSIPWVRSYDGGGLESVSPTTAEIHRAALRYAAEANITPDWALQKVVDDLRRSQAERLGQSTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1Z2</accession>
    <name>A0A518J1Z2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_53830</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="32"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV59355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="58" mass="6303" checksum="85F1C09E39BE4FC5" modified="2019-10-16" version="1">MSSSAHDSTHRSTVPTDKKKHDPPLDKKAPGAVFLLPALTFMVVLVLGVAVFALFRAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J248</accession>
    <name>A0A518J248_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 6">Thiazole synthase</fullName>
            <ecNumber evidence="4 6">2.8.1.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6 8" type="primary">thiG</name>
        <name evidence="8" type="ORF">Mal33_54440</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 6">Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>1-deoxy-D-xylulose 5-phosphate + 2-iminoacetate + [sulfur-carrier protein ThiS]-C-terminal Gly-NH-CH2-C(O)SH = 2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate + [sulfur-carrier protein ThiS]-C-terminal Gly-Gly + 2 H(+) + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:26297"/>
            <dbReference type="Rhea" id="RHEA-COMP:12908"/>
            <dbReference type="Rhea" id="RHEA-COMP:12909"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57792"/>
            <dbReference type="ChEBI" id="CHEBI:62899"/>
            <dbReference type="ChEBI" id="CHEBI:77846"/>
            <dbReference type="ChEBI" id="CHEBI:90619"/>
            <dbReference type="ChEBI" id="CHEBI:90778"/>
            <dbReference type="EC" id="2.8.1.10"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 6">Cofactor biosynthesis; thiamine diphosphate biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homotetramer. Forms heterodimers with either ThiH or ThiS.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the ThiG family.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.10" evidence="4 6"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00060"/>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990107">
        <property type="term" value="F:thiazole synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009229">
        <property type="term" value="P:thiamine diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd04728">
        <property type="entry name" value="ThiG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00443">
        <property type="entry name" value="ThiG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033983">
        <property type="entry name" value="Thiazole_synthase_ThiG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008867">
        <property type="entry name" value="ThiG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34266">
        <property type="entry name" value="PTHR34266"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05690">
        <property type="entry name" value="ThiG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0704">Schiff base</keyword>
    <keyword evidence="5 6" id="KW-0784">Thiamine biosynthesis</keyword>
    <keyword evidence="6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ThiG" evidence="7">
        <location>
            <begin position="18"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="DXP binding" evidence="6">
        <location>
            <begin position="208"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="DXP binding" evidence="6">
        <location>
            <begin position="230"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with DXP" evidence="6">
        <location>
            <position position="116"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>1-deoxy-D-xylulose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57792"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV59409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="284" mass="30328" checksum="FA4E0EA0853B1C70" modified="2019-10-16" version="1">MSTAIPSNDSATDPPLVVGKHTLASRLIVGTGRYDTMPQMAESLEASGADCVTVAVRRERLYDRNGQNILDFIDPDRYTLLPNTAGCYNATDAIRAARLGREILRNLGNAGADWVKLEVLGDSKTLLPDPVETLKACEELVKEGFSVLCYTSDDPIMARRLKQVGAASVMPAGSPIGSGQGLLNPNNLRIILEYLKLDDPDYPVIVDAGVGTASDVAEAFELGADGVLLNTAIAHARDPIRMSRAMRAAASAGRDAFLAGRIPKRLYAQASSPTEGVISSRPYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J268</accession>
    <name>A0A518J268_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Inosine-uridine preferring nucleoside hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_54680</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016799">
        <property type="term" value="F:hydrolase activity, hydrolyzing N-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.245.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011483">
        <property type="entry name" value="DUF1593"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036452">
        <property type="entry name" value="Ribo_hydro-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07632">
        <property type="entry name" value="DUF1593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53590">
        <property type="entry name" value="SSF53590"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021730947" evidence="1">
        <location>
            <begin position="28"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1593" evidence="2">
        <location>
            <begin position="41"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV59433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="332" mass="36908" checksum="A81A741497B8ABFB" modified="2019-10-16" version="1" precursor="true">MKTPQHSQSISLAFLFVFVIGNSAAMAASPPGGALQGERPRLIVSTDIGGSDPDDFQSLVHLLLYADVLDLEGIIASPPGAGRTKDIVEVIDAYARDYAHLKAHSSDYPAPDAMRKIAKQGAHDKAPRKGWSQPTDGSRWIIERAHAADKRPLWILVWGSITDVAQAIHDDPSIKEHIRLYSIGSWNTVQDPAARDYLFEHHKDLWWIESDTTFRGMYMGGVQDGEWGNLRFVEQNVKGHGALGDLFFQKKRDIKMGDTPSLLYLLRGDANDPTAPHWGGAYVATDHGKQYWTDNPDPGLSTGNRAGAKTVSNWRRAYLEDWKQRMDRAAKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IM03</accession>
    <name>A0A518IM03_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Competence protein ComM</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">comM</name>
        <name evidence="4" type="ORF">Mal33_00720</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032508">
        <property type="term" value="P:DNA duplex unwinding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045006">
        <property type="entry name" value="CHLI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001208">
        <property type="entry name" value="MCM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004482">
        <property type="entry name" value="Mg_chelat-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025158">
        <property type="entry name" value="Mg_chelat-rel_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000523">
        <property type="entry name" value="Mg_chelatse_chII-like_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32039">
        <property type="entry name" value="PTHR32039"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32039:SF7">
        <property type="entry name" value="PTHR32039:SF7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01078">
        <property type="entry name" value="Mg_chelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13335">
        <property type="entry name" value="Mg_chelatase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01657">
        <property type="entry name" value="MCMFAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00368">
        <property type="entry name" value="TIGR00368"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="3">
        <location>
            <begin position="218"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="281"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV54128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="515" mass="55805" checksum="12585C88AAE584C3" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IM05</accession>
    <name>A0A518IM05_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Chain length determinant protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_00520</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="450"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="206"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="364"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="512" mass="57170" checksum="3486050BE82E904A" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IM66</accession>
    <name>A0A518IM66_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Haloacid dehalogenase-like hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_01410</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="303" mass="33435" checksum="7217A013AF005A58" modified="2019-10-16" version="1">MSIAVTQSDRFHLDSDTRSELPEPAKGGRAKHYLLASDFDQTLSFNDSGEVLSEMLGLPDFERKVKGLASSHLVQQGGELTYLLLHDPDYRQVRREHLVEAGRRIRLKKNLAPLMDLLDRGIDGHRFTFYVVSASPEEVVRSALEGIVPADRIFGTRLNFAPDSGEISSVAQLTAGYGKVTALDELQSQLGISWDRIVYVGDGSSDVHVMLHVNRCDGYTIAVSENQHLAPIARRTVLSDNAFSVLIPILEDVMGWTDRTKIRELFEASGLDVQGWEKSQVDRLTILPTDADTRDASSAAAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IML6</accession>
    <name>A0A518IML6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cytochrome c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Mal33_02630</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010538">
        <property type="entry name" value="DHOR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06537">
        <property type="entry name" value="DHOR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome c" evidence="5">
        <location>
            <begin position="307"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV54313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="460" mass="50689" checksum="EDDBD78760FBD055" modified="2019-10-16" version="1">MTLSHLFILAATFCGFGWHHSAPDPLTKLTMTNPDASAGRHLFERQWAAGQVDSPEGDGLGPMFNAKSCATCHPGGGASGNEQNVQLISLLTEKLAQPADREAIDLEYQGLLERPGSMFFMLPRHSTSPQYEAWRLERLGLRSNTGSETRDRRIDRVRKRAFARRRPVHEIESNAVHRKLLSERNTPALFGVKQIDAIPLETLQQVAKNQAASGDGISGRVSMVSATQPGRFGWRGQIPTLKRFVEVACANELGLQHEDASQIRGPHNSRDREARDVTRLQILQLVEFLEVLPAPRPQVSATPALQSRVDAGRTAFRSANCHRCHVQTLAAAQDIYSDLLLHDTGPGLWDPIPALPQTIITGQQVRSGGYFGSFTQDTIETVATNIQQEWRTPPLWGVAGTAPYLHDGRAHSLDEAIRLHGGEATAARNLYLQLPKAQQQDLLHFLASLQPPDLKSPTIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMN7</accession>
    <name>A0A518IMN7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_03020</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032740">
        <property type="entry name" value="GxDLY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14607">
        <property type="entry name" value="GxDLY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14606">
        <property type="entry name" value="Lipase_GDSL_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021828009" evidence="1">
        <location>
            <begin position="28"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="domain" description="GxDLY" evidence="3">
        <location>
            <begin position="50"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="SGNH_hydro" evidence="2">
        <location>
            <begin position="203"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV54349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="386" mass="42310" checksum="B4C631515E06A6AF" modified="2019-10-16" version="1" precursor="true">MMTTMMSTLFRSLLAAWILLPASALFAQDVAIDQLDPEMAVAKKTVDGLDWYDVTQWGVEGRILPDQKREQWFDRFPASAKGEVTSNVWSLSRDSAGMMVRFKTDATEIHVHYKLKKSRLAMPHMPATGVSGVDLYARDGAGNWRWVQVTRPSSQEMKVKIVGDLAEGMREYAAYLPLYNGVEFMSIGVKPGSHFEGLAPRPKPIVFYGTSITHGACASRPGMVHTAILGRRMDMPVVNLGFSGNGRMDKEVGDYLTQIDAAAFVIDCLPNMGPADVTAKCIPLIKQLRAAHPSTPIILVEDRRNTNDWILPARQAHHTKNHAALKAAHASLVADGVTGLHYITGDTLYGDDSEGATDGSHASDLGFMRQAMQFEPILRGALGEGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMR4</accession>
    <name>A0A518IMR4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L32</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 6" type="primary">rpmF</name>
        <name evidence="6" type="ORF">Mal33_03340</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the bacterial ribosomal protein bL32 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00340">
        <property type="entry name" value="Ribosomal_L32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002677">
        <property type="entry name" value="Ribosomal_L32p"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044957">
        <property type="entry name" value="Ribosomal_L32p_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35534">
        <property type="entry name" value="PTHR35534"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01783">
        <property type="entry name" value="Ribosomal_L32p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="SSF57829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01031">
        <property type="entry name" value="rpmF_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV54380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="60" mass="6920" checksum="F296F6338F62DD70" modified="2019-10-16" version="1">MAVPKRKHSNSRTNKRRSHDHLSRKQLTYCPQCSSATPTHTVCPKCGYYMGRTIVEVNEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMR5</accession>
    <name>A0A518IMR5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA polymerase III subunit delta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_03330</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009360">
        <property type="term" value="C:DNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008921">
        <property type="entry name" value="DNA_pol3_clamp-load_cplx_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010372">
        <property type="entry name" value="DNA_pol3_delta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005790">
        <property type="entry name" value="DNA_polIII_delta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06144">
        <property type="entry name" value="DNA_pol3_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48019">
        <property type="entry name" value="SSF48019"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01128">
        <property type="entry name" value="holA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA_pol3_delta" evidence="1">
        <location>
            <begin position="25"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="352" mass="38621" checksum="1E26D35BF2A2AE5A" modified="2019-10-16" version="1">MPLLNAFDLLTAASDSAPSAVTVLFGDDPMLRSWTLRKLLGLDAAEEDRPDSIDLDGELAEWKDVRDELQTGSLFSMGQPRSIVVRDADKFVSKYRAELEAYVAKPSSAGLLLLELKSFPGNTRLYKAINKTHLLVQCAIPAGSGRSTKPDLNKLKSFLCGFVAARHQCKLQKGAAETLVELSGTSLGLLDTDIAKLAVCVERGAPVTDDMVRKFVGGWRSKTTWEIIDAATEGNSGEALRQLDHLIASGEKAFALLPQISWSLRRLGLAAAAIDYAEKSGRRISLSDALQQAGFRPFDMKKAEAHLRKIGRPRAQRMLGWLLDADLKLKGTHSTDDRARWVLEELFLKMAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMU3</accession>
    <name>A0A518IMU3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_03620</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="105" mass="12079" checksum="8C9932AA8BF82A3A" modified="2019-10-16" version="1">MVAEAAAKPTQRKKQRRRQIDPTTCERDYSDKEIEFMHALDEYKRNAGRMFPTCSEVLEVIRGLGYVQLTDEQAAMLQTDEFDCEEDSYGQDSDDDEFADLGDEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMV6</accession>
    <name>A0A518IMV6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ysc84 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_03750</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007461">
        <property type="entry name" value="Ysc84_actin-binding"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04366">
        <property type="entry name" value="Ysc84"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021991147" description="Ysc84 domain-containing protein" evidence="2">
        <location>
            <begin position="23"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="domain" description="Ysc84" evidence="3">
        <location>
            <begin position="100"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="329"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="333"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV54421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="351" mass="36945" checksum="ABE80B91EAA0F6FE" modified="2019-10-16" version="1" precursor="true">MARYITCFLLLALATPPQPASAQSAEEGIVLAASAVLSQAMSTSLNQIPRSMLTDAHGVAIIPNVIKGGFIIGARHGRGLLFVRDPNGIWHAPVFITLTGGNIGWQAGLQSSDIVLVFKTAKSVEGILSGTLTIGADAAAAAGPVGLQGAVATDGRLQAEIYSYSRSRGLFAGVAIDGSVLQIDQLSTGTYYRSPAPGQPVVIPPAAQELTQRIANYAAGVAPTEGTSTSQMPPLAQRYTAQESDVLRGQLLQIAPKLFALLDEQWKTYLALPFSATADGAHPTPQQVQQTLAHFQSVATNPQFQQLAARPEFQSVYGLLQHYQQSLTPNTQTLQLPPPPTATPPPAVPAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMW1</accession>
    <name>A0A518IMW1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_03840</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="36" mass="3996" checksum="3D8355DA4E33F358" modified="2019-10-16" version="1">MGSAVPGIAAQFAVEQLRAEWDETVLDHFYAGFNRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IN26</accession>
    <name>A0A518IN26_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="10">EamA-like transporter family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Mal33_04510</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EamA transporter family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004626">
        <property type="entry name" value="RarD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22911:SF114">
        <property type="entry name" value="PTHR22911:SF114"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00688">
        <property type="entry name" value="rarD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="33"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="63"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="94"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="118"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="199"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="232"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="259"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="9">
        <location>
            <begin position="3"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="9">
        <location>
            <begin position="140"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV54497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="293" mass="31655" checksum="E42A731C43CFDEA0" modified="2019-10-16" version="1">MCAVGAHMMWGFFPLYWHLLDYVPSTTLTAYRVIWSFLLLMTLSIAMPRLRRALLQLREPRKLAIYAATATMIGINWGAFMYAVGSGQVLQASLGYYINPLLNVLLGVVVLGERLKPFQWIAVGFAAVGVAVMVMMGSGMPWIALAMASAFATYGLLKKKATLPPLEGLSIETGLLFPAALAFLLLQSPDPGAQPYTPVTWLLLIIGGALTIAPLALFATAAKRVTLTTIGILQYVGPTLQWFVGVVLLGEAFGGSKLIGFLFVWTGVTVFIVGGLQMQSRATRQARQVALAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INC7</accession>
    <name>A0A518INC7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Outer membrane biogenesis protein BamB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_05580</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018391">
        <property type="entry name" value="PQQ_beta_propeller_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002372">
        <property type="entry name" value="PQQ_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13360">
        <property type="entry name" value="PQQ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00564">
        <property type="entry name" value="PQQ"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022243283" evidence="2">
        <location>
            <begin position="22"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="755" mass="80607" checksum="327AEA294FF29E70" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INK9</accession>
    <name>A0A518INK9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Rhomboid domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Mal33_06310</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022764">
        <property type="entry name" value="Peptidase_S54_rhomboid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023826">
        <property type="entry name" value="Rhom-like_SP_proteobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01694">
        <property type="entry name" value="Rhomboid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="SSF144091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03902">
        <property type="entry name" value="rhom_GG_sort"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="79"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="104"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="132"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="Rhomboid" evidence="6">
        <location>
            <begin position="37"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV54676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="202" mass="22336" checksum="67ABD8BB7F445F5C" modified="2019-10-16" version="1">MKTIPVPVTITIVLISILAAVFPSLTSLLELDFQRAAQGEIWRWISGHVVHFDWSHFFWDVSMFATLSAICESKYRRVYAPILIGSMLIISLSLAIVCPEIHCYRGLSGIDTMLFGWWVIDWMRTNLHAKDLPAAGLGGMMLLGLVGKLGYEAVFHQTLFVQSDAFVPLVEAHIAGLICGATAALGVPVVQNWTRVRQPVSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INR7</accession>
    <name>A0A518INR7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_06850</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
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    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026392">
        <property type="entry name" value="Exo/Archaeosortase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019127">
        <property type="entry name" value="Exosortase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09721">
        <property type="entry name" value="Exosortase_EpsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04178">
        <property type="entry name" value="exo_archaeo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="86"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="123"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="192"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="217"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="254"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="328"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV54970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="551" mass="61577" checksum="2B52CB69571C1FFB" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPH9</accession>
    <name>A0A518IPH9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_09730</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025904">
        <property type="entry name" value="Tubulin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13809">
        <property type="entry name" value="Tubulin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="4">
        <location>
            <begin position="18"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV55005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1064" mass="117072" checksum="AC49241F4FDD8D6B" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPJ0</accession>
    <name>A0A518IPJ0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Arylsulfatase</fullName>
            <ecNumber evidence="7">3.1.6.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">atsA_6</name>
        <name evidence="7" type="ORF">Mal33_09840</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="PTM">
        <text evidence="3">The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the sulfatase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.6.1" evidence="7"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004065">
        <property type="term" value="F:arylsulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032158">
        <property type="entry name" value="DUF4994"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024607">
        <property type="entry name" value="Sulfatase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16385">
        <property type="entry name" value="DUF4994"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00523">
        <property type="entry name" value="SULFATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00149">
        <property type="entry name" value="SULFATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022105557" evidence="4">
        <location>
            <begin position="19"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase" evidence="5">
        <location>
            <begin position="34"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4994" evidence="6">
        <location>
            <begin position="390"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="modified residue" description="3-oxoalanine (Cys)" evidence="3">
        <location>
            <position position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR600917-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF16385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV55016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="515" mass="55809" checksum="6AE65D7FC43ED8F9" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQ69</accession>
    <name>A0A518IQ69_9BACT</name>
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        <submittedName>
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        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">hydN</name>
        <name evidence="6" type="ORF">Mal33_11970</name>
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    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12838">
        <property type="entry name" value="Fer4_7"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="62"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="4">
        <location>
            <begin position="234"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="5">
        <location>
            <begin position="414"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="5">
        <location>
            <begin position="483"/>
            <end position="512"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV55227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="575" mass="64564" checksum="C333A0C74B6DA66D" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQI7</accession>
    <name>A0A518IQI7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SHD1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_13040</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
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    </dbReference>
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        <property type="entry name" value="Quinoprot_gluc/sorb_DH"/>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50952">
        <property type="entry name" value="SSF50952"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021706517" description="SHD1 domain-containing protein" evidence="1">
        <location>
            <begin position="27"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="domain" description="SHD1" evidence="2">
        <location>
            <begin position="87"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="801" mass="88160" checksum="94578A84EAF32CA5" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQL3</accession>
    <name>A0A518IQL3_9BACT</name>
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        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_13460</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="component" value="Chromosome"/>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
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    <feature type="chain" id="PRO_5021736005" evidence="2">
        <location>
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            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="132"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="165"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="243" mass="26416" checksum="D5F9A9673EB4E2A5" modified="2019-10-16" version="1" precursor="true">MKNMPKHAVVALAAFAFASFSQMQPATAQHWHGYGHGAHHHTNHGHFYGHYQGGHHYAHDSYHYQDSHHGHAPIALGYVDMPLNQYHSNNSVYCPDDVGCPLQYNQPALGGLSQQNPPYQDVPYLSAPRQYEIPNGAAGSYNDHGHHANDGHDHGDHSHDGHSHGPVNPSLQNPAVTFGTPDRQPMTAPTLPNRNAVPELPRYEAPRNRPAQPSSPPTNNGPIRMDGPPPSLTALGSPSLTVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQN7</accession>
    <name>A0A518IQN7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_13780</name>
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    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025668">
        <property type="entry name" value="Tnp_DDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008490">
        <property type="entry name" value="Transposase_InsH_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13751">
        <property type="entry name" value="DDE_Tnp_1_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05598">
        <property type="entry name" value="DUF772"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF772" evidence="2">
        <location>
            <begin position="18"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="domain" description="Tnp_DDE_dom" evidence="3">
        <location>
            <begin position="369"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="221"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV55407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="494" mass="56138" checksum="6417057927306A19" modified="2019-10-16" version="1">MEQLPVRDLATGFRDDYGRPTKDIYVAIGALILQQLHDFTDQQTTEAIALNIAWHYALDIRHNSDAYICERTLRNYRKMVLDAGLDQVLFRTLTDKLIKEIGIDTSKQRLDSTAVRSAIRGLTRPEILVEATCKFLRELKRKHPEQYSLVDPEIIRKYVTRTGDVCFGDTRPSESRKRISEAAGNVFKLVEFFQETECSTLESYQLLRKIFHEQCEVSSSGEAPVTVRPPSKTGCDGVINPADPDARYNKHRGTGYLVQIMETYDEEDSEEPDTSITPKPDLITHVAVDPLTMHDKDALTPAFDDTEQRGIKPQELLADSHYGSTECIENGNGRDVEIVAPAQTPKGKLQGKFTLEDFDVDDEGRITRCPAGQRPAETSVAGIRLQVIFMAETCESCPHKDRCPASSVGRSSVRYQYTHDRVRLRLRRMKERGDEFRDRYRWCVGVEATMSRLKYQMGMIRLRVRKMLNITYVATLCALGLNIRRVAAYRSAVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRB1</accession>
    <name>A0A518IRB1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Polysaccharide biosynthesis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Mal33_15960</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029303">
        <property type="entry name" value="Polysacc_synt_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002797">
        <property type="entry name" value="Polysacc_synth"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01943">
        <property type="entry name" value="Polysacc_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14667">
        <property type="entry name" value="Polysacc_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="44"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="86"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="112"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="294"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="325"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="358"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="387"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="417"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="450"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="domain" description="Polysacc_synt_C" evidence="7">
        <location>
            <begin position="329"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF14667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV55619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="488" mass="53343" checksum="4C44775DB716CCEC" modified="2019-10-16" version="1">MTTMGKIRRNAVAIFTGDLVNKASTFAVYAMLSRYTSLESFGLLQFGLLVLYTFNVFAAAGLPTLLTRRVARHANRSRHLLYHGYAGALASSLLAMLGMILFAFVMRYDAEMRWVLCLLSIAIVPYALTLVAEAVIRGRERMHLIALANLPGNALLVGGAFAVLSQGYSIYWLAAVVITARTATFLLTHAMASYCCQHSLAVPGVGFRVGMKQLKHSLVFFGNDGVNAIWSALDQVMLSKFASEREIGLLGSSYQILQPILMVYRAVGTSAFPTLCYTASRDAIAEMVQSLIGLLWRLSTPAAIGLFLLADEILVFAYGNEEFRAAAVVIRILVFTLFLDPVTPLLGHALWATKNEAVVLRIVLVNLMANVVVGCLLISQFGLIGAAVTYVSINFFNVLQHKYYFRREIAPLALGREWLRGLPATLCLLAVVACFVQWDAVRAGQHHWISLGQAIIALTLGMIVYVPLAFPGLCSHGVRMVTGKLEKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRD9</accession>
    <name>A0A518IRD9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_16560</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022076010" evidence="2">
        <location>
            <begin position="26"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="149"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="308" mass="33621" checksum="2EA2563D8BF8FED1" modified="2019-10-16" version="1" precursor="true">MTRIAFSASLPMTLLLAVLVGSAGAQQTNNASPAVQAEPAYLLHYQLKAGETLQYQVTHVAKTKTRIRGKDELTNVRSLSTKVWNVESVDPATGQMTFVHMVQDTELSQKIGEADEVRWDSKSGEDPPYQFEAVKATLGKPLTTVSINGQGQEKERESHAGTKANLGMGGLTLPLPPKAIKVGDTWAVPRQTHARLAGGQVKRIDVRELYTLKKVQTGVATITVQSQPITPISDPKVKSQVVQQLSNGTIKFDIDAGRVLSKQLDWDETVVGFEGAESMMEYRARLNETLVETKTSVAARSIDQLKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRI9</accession>
    <name>A0A518IRI9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Xylose isomerase-like TIM barrel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_16880</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="SSF51658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="390" mass="43153" checksum="C175E0D7FF5D9106" modified="2019-10-16" version="1">MKWSCGVTSQWMTGYCTNVHAGTDIAQIRNNLDQVAVAVREKLGASSMGVGLWIPAEAASELAAPNASAEFASWLADRHLIPFTINGFPYGNFHQPVVKHRVYLPTWWETARRDYTLQLVEILHQILPAGQSGSISTLPLGWGEPQPSGEQMQQAAANLKQVAERLAQIEQESGRRIVIAIEPEPGCAIDTTDDMIKFFDEYLPGANLRRYLTVCHDICHAAVMCEDQSVVLRRYADAGIGIGKVQVSSAIEVPWHAMQPDAQRAAIDQLAGFAEDRYLHQTMVVSKTGQQRLVEDLPELLASSDPTQDHSWRIHFHVPIYLDRFGQLNATQPAVVECIGALSATEGLDFSGHMEAETYAWGVLPSELKVDNLADGIAEEMRWLQLQIGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRZ6</accession>
    <name>A0A518IRZ6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Na(+)/H(+) antiporter subunit D</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">mrpD_1</name>
        <name evidence="4" type="ORF">Mal33_18450</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <source>
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        <source>
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    <sequence length="567" mass="61932" checksum="137777E19AD49871" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </location>
    </feature>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="QDV55936.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="351" mass="39208" checksum="06FE0A4A80F839FB" modified="2019-10-16" version="1">MSTQAPPEFTEQDAQRLHEARNRVREQLGKVIVGQQNVIDQLMISLFSRGHCMLEGVPGLAKTLMISTLARCLDLSFNRIQFTPDLMPADVTGTEIIEEDRASGHRQMRFMPGPLFANLVLADEINRTPPKTQAALLEAMQERQVTVSGQRHPMADPFFVLATQNPIEQEGTYPLPEAQQDRFMFKVYVEYPNFDEEFEVARRTTGASVDDVQPVLKAEEIVRLQQLVRQVPVSDHVVRYALSIVRQTRVGSEGVPDFVNDLVGWGAGPRAVQNLILGGKARALLEGRFHVQPSDIQALAPAVLRHRMVVNFAAESEGVTSDDVVARILAVTPENEDELSRDARFKKIFAS</sequence>
</entry>
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        <submittedName>
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        </submittedName>
    </protein>
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
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                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
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        <property type="project" value="InterPro"/>
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        </location>
    </feature>
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        </source>
    </evidence>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="507" mass="56012" checksum="79F2099716E45BEE" modified="2019-10-16" version="1">MNRLSFPGSFLPVVSRCWSPLQNKPAVLTVASLVWFSVCGLSVPASAQKGKPDPNVTAAQAVDARLAETAAWADLFNGKDLSGWKGDTAGYVAQDGLLVCKKGAKLLLTEKEYSDFAFQFDFKLEPSGNNGIGIRVPEGGHPSTDGMEIQILDHDGDKYSTQIDLGNGKTRSVNQLKPWQYHGSVYGIYPAKTGYLKPVGQWNTQTIVAIEDHIIVILNGAVIVDVFLDDQMPIDGKAHPGKDVRKGHLVLSGHSDHVEFRNLRIADYSVSPPRPQSQTDNTPPSGFVSLFNGQDLSGWKGLADKNANKRRSLSGEALATAQAAADEVMQAHWSVVEGVLTYDGKGQSLCTDKDYGDFELYVDWKIPPGADSGLYLRGTPQVQIWDPWDPRVKPGQSPPADPQAWVAAYTNGRNLGSGGLWNNRRWRNAPTMLADNPPGQWNTFFIRMVGEKVSIWLNEKLIVDRVELENYWDRSGKQPLARADQIELQHHGSELFFKNIYLRQLPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISC9</accession>
    <name>A0A518ISC9_9BACT</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">Mal33_19850</name>
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            <taxon>Planctomycetia</taxon>
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            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="74" mass="8346" checksum="5D69F681D454B7EA" modified="2019-10-16" version="1">MTDSQKDLVLHLLQQGNWHDAVVACCEETGADVETARAAVRQLANEHRLTQPRNWWLIAVTMLMTSVLAVYVLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISG9</accession>
    <name>A0A518ISG9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative HTH-type transcriptional regulator YusO</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">yusO</name>
        <name evidence="3" type="ORF">Mal33_20110</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023187">
        <property type="entry name" value="Tscrpt_reg_MarR-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01047">
        <property type="entry name" value="MarR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01117">
        <property type="entry name" value="HTH_MARR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="2">
        <location>
            <begin position="30"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="170" mass="19390" checksum="7668FCAE416A88DC" modified="2019-10-16" version="1">MSPTKKSEPTQDPRPLQQELKKKAPFTSPHQEAVLNVLRTSDQFQNRFGRLLRKYGLTGSQYNVLRILRGEGKPLPSLEIADRMIQVVPAITGLIDRLEKQGFVSRDRSTIDRRVVNVAITNKGLDVLEPLDRPVNTLHKQLLKHLDRSELAQLSHLLEKARSRIDTLDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISL7</accession>
    <name>A0A518ISL7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_20580</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="79" mass="8437" checksum="50C79FD968D02B6C" modified="2019-10-16" version="1">MSEGSRWPERSEYHRYTTPETIAAPDGGAQRSAIPSGASRIVTLHSGGAPLRDDLRLPSVIPSGSIVDSADRSASMMRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IST5</accession>
    <name>A0A518IST5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fatty acid oxidation complex subunit alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">fadJ_1</name>
        <name evidence="3" type="ORF">Mal33_20920</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006180">
        <property type="entry name" value="3-OHacyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006176">
        <property type="entry name" value="3-OHacyl-CoA_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006108">
        <property type="entry name" value="3HC_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00725">
        <property type="entry name" value="3HCDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02737">
        <property type="entry name" value="3HCDH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00067">
        <property type="entry name" value="3HCDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3HCDH_N" evidence="2">
        <location>
            <begin position="18"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="3HCDH" evidence="1">
        <location>
            <begin position="197"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="427" mass="45968" checksum="A2B87DE0FEC0215D" modified="2019-10-16" version="1">MARDGASIFLNAPTHWNISLIGAGIVGRAIAWDHLRCKIPIRLIDSNPQQLAATVESLLAETGGTKTDPIRWGDEAWATELVPAGAMAPQPTDQAIVIESIVERREPKQRVLATAEQLSAADAILATNTSTIPLADVTQQVQQRGRCCGLHFFMPVDQRPLIEIITTEATTDATVAIAKRYAAALNKQHLIVRDAPGFVVNRMLVPYLNESVQLLCSGTSPLQLERVAIDCGMPMSPLELMDWIGMETGFHAGRAIWQAFPSRIEPSPLTPAMVKAKLVGRAGGEGFYSYHVGSRSGDLGPTAQTLVQRYTRDEVSLSDWQVAARLFFPMLIEAACILLQNVVGDLQSIERAMGGGLGFRDPDGFLARFDRIGPGQCLAELNHLATLGRRFASPPELLASLESAGSVSDAFGMLCSADAGSSPNDSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IST9</accession>
    <name>A0A518IST9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">Pyrroline-5-carboxylate reductase</fullName>
            <shortName evidence="2">P5C reductase</shortName>
            <shortName evidence="2">P5CR</shortName>
            <ecNumber evidence="2 3">1.5.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">PCA reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2 6" type="primary">proC</name>
        <name evidence="6" type="ORF">Mal33_21340</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>L-proline + NAD(+) = 1-pyrroline-5-carboxylate + 2 H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:14105"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15893"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="EC" id="1.5.1.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 3">
            <text>L-proline + NADP(+) = 1-pyrroline-5-carboxylate + 2 H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:14109"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15893"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="EC" id="1.5.1.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 3">Amino-acid biosynthesis; L-proline biosynthesis; L-proline from L-glutamate 5-semialdehyde: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2 3">Belongs to the pyrroline-5-carboxylate reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.2" evidence="2 3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00098">
        <property type="reaction ID" value="UER00361"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004735">
        <property type="term" value="F:pyrroline-5-carboxylate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055129">
        <property type="term" value="P:L-proline biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01925">
        <property type="entry name" value="P5C_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028939">
        <property type="entry name" value="P5C_Rdtase_cat_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029036">
        <property type="entry name" value="P5CR_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000304">
        <property type="entry name" value="Pyrroline-COOH_reductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11645">
        <property type="entry name" value="PTHR11645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03807">
        <property type="entry name" value="F420_oxidored"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14748">
        <property type="entry name" value="P5CR_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000193">
        <property type="entry name" value="Pyrrol-5-carb_rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00112">
        <property type="entry name" value="proC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00521">
        <property type="entry name" value="P5CR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0521">NADP</keyword>
    <keyword evidence="2 3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 3" id="KW-0641">Proline biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F420_oxidored" evidence="4">
        <location>
            <begin position="8"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="domain" description="P5CR_dimer" evidence="5">
        <location>
            <begin position="165"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF14748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV56155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="271" mass="27640" checksum="2306F686ABE515E5" modified="2019-10-16" version="1">MESTKPQLALIGGGKMGRALVQGMIDAGFTTADRVTVGDRNTDSQAWWKQNVPQAKVTADSKTAVEAADVILLAIKPHGVPAVVAELKRTARKSLLISVAAGIQLGTLVRQFGSSRVVRVMPNTPSVVGAGASAYCCGDDVSSEDAAYVDGMLSSVGKAFRVEDKLMDAVTGVSGSGPAYVCMIIEALADGGVLSGLPRELAMQLATQTVLGTATLIQQTGSHPAVLKDAVASPGGTTIAGIAALERGALRNTLISAVQAAALRGEELGKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISX8</accession>
    <name>A0A518ISX8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_21770</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="240" mass="25841" checksum="40FA32A4C35F53EF" modified="2019-10-16" version="1">MAVILFIRGLARESVDVPSWQIVLVAMLLIAITNAARWLVIRSTGNSRGAASPQPRWLPFAFTPAAVILTLWLTGLHPSGIAAFFIWLLLATSEIACLAIYWPFASAFPDLLASVQQRVGLSASGPAADVEAVDEYAPPLEDDVDQQIQRRVRDGVDEVHGLLRVRYEPGQRVASLFAGFVPPLLPAPTAEAEAVAGSEATVSVAGIHAQGIELELRRDSVDDGETSTIVEFYARAADQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISX9</accession>
    <name>A0A518ISX9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RNA polymerase sigma factor SigA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">sigA_5</name>
        <name evidence="7" type="ORF">Mal33_21600</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000943">
        <property type="entry name" value="RNA_pol_sigma70"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007630">
        <property type="entry name" value="RNA_pol_sigma70_r4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04545">
        <property type="entry name" value="Sigma70_r4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00046">
        <property type="entry name" value="SIGMA70FCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00716">
        <property type="entry name" value="SIGMA70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="RNA_pol_sigma70" evidence="6">
        <location>
            <begin position="402"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV56179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="438" mass="50202" checksum="7B9EFBADD753EC42" modified="2019-10-16" version="1">MVRFATKSQSNRWFSQSGSHNSTQSNNDNEGLEEYFADISKTRLLTTAEEIEATQRIKKAGIVYRHCLLMHPEILPQIIDSLATVDARDVRIDTVVEVAPNDLPRIQFLRKAIPHVIESLQRIDDENRRDRKQIGMRRCSQVKRQAALGRMRRRRHSVRNLVNELPIRVAVLESLFDASDDRVAAGQLARVTRRAAALRVHLTSLKQGFISHHLRLVIPIAKQYRGRGLGFLDLVQEGNAVLMKAIEKFDPDRGFRFSTYATWWIRQAISRAVAVQGRLVRVPQAAFSGVKQVRQTQESFYLRHRRDPDPQEIARDTGMSFESTKRALGALREVVSIHDRTDDDQMTLAETLPEVSETSDPAFLEEQQNLRPMVLGMLSRLDPRERRIVELRFGIKDGKPRTLTQVSSAMSLSRERIRQIQTQAMSKLEDMSEGMDDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IT40</accession>
    <name>A0A518IT40_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nmad3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_22460</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041135">
        <property type="entry name" value="Nmad3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18754">
        <property type="entry name" value="Nmad3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nmad3" evidence="1">
        <location>
            <begin position="4"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="245" mass="27525" checksum="0EA4F10C873C9B5B" modified="2019-10-16" version="1">MSRKAVLLRVGIDSGCGGIQSPLFSDGSFEFVCIPDNKRVSVHQYGSLIGKNGRPHSDYFPLRKQETVAEQHIHLDPEFETFSYGDPTTPKRSLRKLERGDYLIFYCGLQEWNEETGWHTDTSPALYLAGYFVVELAGMAADFTKTTLKKEFGKNFHVRYPPVLEKQRDDLVLVKGGPGSRLMEKAHRISSVGKDRAGKPLKVLSPQMQKVFGTFGGKVSIQRSPPRWVEPKFVDSTINFVVGLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITA0</accession>
    <name>A0A518ITA0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_22820</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010869">
        <property type="entry name" value="DUF1501"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07394">
        <property type="entry name" value="DUF1501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="441" mass="47485" checksum="DE70847B8FE0CE68" modified="2019-10-16" version="1">MNWYKDAVSRRAMMRLAAWQSFGVSVLSFAGGRLLADDPFAEFSDEAIAAKQAGDKPAEAKSTGKRRLIYIFSAGGMSHVDTFDPKPGTDSQGPLGAISTNISGVQFGQSLPKLAAMADKLAVIRSMSTETGAHGPGSYLMRTGQKEIASTRHPGIGAWMQRFNGRIHPALPPSVNIGGGIGPGYLGAKFAPVPIGDPNRGLQNTSGPEYLADDQFMRRMYLSAALDREFRSKVHLKQVDGYDDLYREAIRLLKSDDLKAFDLNLESEEAKERYGKSKVGRGCLLARRLVENDVQYVEVQAGGWDMHNDIADAMTSRGSELDQALSALIEDLTASGLIHETTIVVATEFGRNPSINQNAGRDHHPAVFSCAMAGAGVRTGTILGSSDSKGFLVDEYQVSVPDFMATIGKALQLPVDKEIHSPDGRPFTFANGGMAIDEVLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITI9</accession>
    <name>A0A518ITI9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_23960</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="271"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="331" mass="35536" checksum="4120071D6874E619" modified="2019-10-16" version="1">MPAAKPQLPVSGDLARFGRACGADPVIDRTGGRFGAGIIRGVSLSVVGEAIGHDYWLDAMTIDQVAKFSQATGEAGLKCRFSHPGMSSDGIGRHLGRIHDVRAIGDKAVGDLHFTKSSHETPDGDLAEYVMSLTSEDPKAAGLSIVFVRDVAAEKKFSEENTIERKYSDVRKKKRVERHFVSPDRANKKGLPHCRILQLKAADIVDEPAANPDGMFDAQPLARNADDLLSYAAGLTKEKPDATALGIDGDRASQFLGRWLRSHGLSLVRSDKQVGTAEASRKKPAASSRNVAPQPQTDASLERFDKACDALLEAYAGRDDKLSHLGTPGSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITU0</accession>
    <name>A0A518ITU0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Methyltransferase</fullName>
            <ecNumber evidence="4">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">dpnA</name>
        <name evidence="6" type="ORF">Mal33_24940</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the N(4)/N(6)-methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="REBASE" id="355897">
        <property type="entry name" value="M.PbaMal33ORF24940P"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008170">
        <property type="term" value="F:N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006306">
        <property type="term" value="P:DNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002941">
        <property type="entry name" value="DNA_methylase_N4/N6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001091">
        <property type="entry name" value="RM_Methyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01555">
        <property type="entry name" value="N6_N4_Mtase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00508">
        <property type="entry name" value="S21N4MTFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N6_N4_Mtase" evidence="5">
        <location>
            <begin position="40"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="N6_N4_Mtase" evidence="5">
        <location>
            <begin position="185"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV56503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="253" mass="27890" checksum="D403762F26CF974A" modified="2019-10-16" version="1">MICERCKMAEAVNVERGKDWQSYFGDTRSVLSTLPDESFDAIVSDPPYGSGANTVAGRLSSSSSKYRSTGAKPLPDILGDSMVPEAWQGMMQSIMAEAYRVARPGADVILFCDWRCYPALMQIVGGARFQLRGVATWDKKNSRPMKNGFRSQTEWIINARKPGKLPRPKDVYLPGVFTFQTMSNGKRHLTQKPLALMAELIRLVPDGGHVLDMFQGSGTTGVASVQRGLKYTGIEGVKEYHEIACERLTDTAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITU1</accession>
    <name>A0A518ITU1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Caudovirus prohead protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_24980</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006433">
        <property type="entry name" value="Prohead_protease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04586">
        <property type="entry name" value="Peptidase_S78"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01543">
        <property type="entry name" value="proheadase_HK97"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1188">Viral release from host cell</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="229" mass="25745" checksum="64A19D54599FB52C" modified="2019-10-16" version="1">MTKKTDHRAGYHRSDRAGRESLVVHQRHSRVERRSGAADDSPSMIRGYGAVYYREGDESTEYWLWDDLVERIRPGAFDRAISEQQDVRGLFNHDPNQVLGRTASGTMRLLSDSVGLAYEIDIDPKIQLHADVGRMVDRGDVSGSSFWFLPKRISWTETDDYAVRWIEDVDLYDTGPVTFPAYDGASSGRSADAEAIVTELANYRTERNAAEAEPYDIAIAARLASLPPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IU45</accession>
    <name>A0A518IU45_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Beta-galactosidase trimerization domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_26030</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
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            <strain evidence="3 4">Mal33</strain>
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    </dbReference>
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        <property type="match status" value="1"/>
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    <keyword evidence="1" id="KW-0732">Signal</keyword>
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        <location>
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            <end position="28"/>
        </location>
    </feature>
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            <end position="738"/>
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    </feature>
    <feature type="domain" description="Glyco_hydro_42M" evidence="2">
        <location>
            <begin position="414"/>
            <end position="596"/>
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    </feature>
    <evidence type="ECO:0000256" key="1">
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    </evidence>
    <evidence type="ECO:0000259" key="2">
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="QDV56611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="738" mass="83848" checksum="0CC003E3C42AEEE3" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
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            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
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                <person name="Overmann J."/>
                <person name="Amann R."/>
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                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
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            <strain evidence="1 2">Mal33</strain>
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        <source>
            <dbReference type="EMBL" id="QDV56699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="112" mass="12920" checksum="0056446C8256BF31" modified="2019-10-16" version="1">MIRPTYMPGDWVVYRKSKTGPLPGPHAQQVHPSPKGEQYSYVVEKYWVVKQVFSDGRLLLKTRRGREHIIDSADPGLRLAGFLRRWMHRDSYTIIEKLTRDSGSSPTISHEA</sequence>
</entry>
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        <name type="scientific">Rosistilla oblonga</name>
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
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                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
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            <end position="33"/>
        </location>
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            <end position="498"/>
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            <dbReference type="EMBL" id="QDV56802.1"/>
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        </source>
    </evidence>
    <sequence length="601" mass="66666" checksum="AA209012540540F9" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
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                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
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                <person name="Kallscheuer N."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
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    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
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            <begin position="135"/>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56818.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
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    </evidence>
    <sequence length="1133" mass="123974" checksum="CA3953ECD6B65AC4" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUR9</accession>
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                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
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                <person name="Kallscheuer N."/>
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                <person name="Pohl T."/>
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                <person name="Overmann J."/>
                <person name="Amann R."/>
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                <person name="Mascher T."/>
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                <person name="Devos D.P."/>
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                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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    <proteinExistence type="predicted"/>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="17"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="126"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="187" mass="19984" checksum="6770A28EA19CABEF" modified="2019-10-16" version="1">MFYILFLIATATRLMPHPPNLVCVGAIGLFAGCYLRGRTAWLLPIGAMLASDVIGHVLRLPGMGFYNPAVFCMVYAGIAASALIGRGLAKNRTAARIGGAAVASSIVFFLASNLGVWFAGQYPPTVAGLIACYTMAIPFLTNTLIGNLLYSAVLFGTYEFSQSQWPARLTRLVSKQPAMQPAFARKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUW6</accession>
    <name>A0A518IUW6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HAMP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_28680</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="26"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="65"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="3">
        <location>
            <begin position="88"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV56867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="169" mass="19057" checksum="A010B5AB7359FD30" modified="2019-10-16" version="1">MSKSTRRKSNFVDPETQLSLLKRITLHWCSFIAANSVALVIWLMLFEQEPGASWGETGNLFMQRYAPFLIISAAMLPIFLRDTMRLSNRFAGPIQRLRRAMEAVAEGSHVKPISFRKGDFLQDLASDFNLVLARYQKSQSDSATRVVKSEQNETQVSAAEIESESPVSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IV02</accession>
    <name>A0A518IV02_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_29010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="354"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="427" mass="46881" checksum="93680B7BC744D186" modified="2019-10-16" version="1">MIAAQPQTSRRPNAAVVGILICGLGFLIGCRSGGAPQRKIDPQLKNHAEAATEAFAEGQLEDAVKQYRKVIRRAWAMDDPLESGNNAYNMAAAMTSMSRVAEARDWLVDARVELYRAGKPDGNTWLLEAKLAQNQCRFDEAARLIQRASCSEPPCEGDSGDCLCGPHDPCEGSCAAKIPCVGEKLEQRKQLADCQQTFQIQIHLAQARWYAEQYDLPNARCHYQTACELAAEICDFELQAELQSVAAMIHLACGQFLQAGWHLDLEAKNLRLAGNYREIPRALELASAAYAQAARPALAADRLCRVARIWYGRGNINRSWKYVKDAIPMAEMSGSASTQIRLALLVHELRQEIDDKSDNDAAPRSDLDPTPELAAHDSSQATDSADAAVHPADPIQEAELLMLEGPEKQASAVIERLANQRPLHSDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IV33</accession>
    <name>A0A518IV33_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_29620</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="14"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="73" mass="8346" checksum="618E2AB2E291E4A3" modified="2019-10-16" version="1">MDPSYYFTKNPDLAALHVAAFFFVLGLAVGWVLWSGNRRQVRNLDRENDAIAKQLEADCFRQSQLERESSLLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVC8</accession>
    <name>A0A518IVC8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta</fullName>
            <shortName evidence="13">ACCase subunit beta</shortName>
            <shortName evidence="13">Acetyl-CoA carboxylase carboxyltransferase subunit beta</shortName>
            <ecNumber evidence="13">2.1.3.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13 15" type="primary">accD</name>
        <name evidence="15" type="ORF">Mal33_30430</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12 13">Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>acetyl-CoA + N(6)-carboxybiotinyl-L-lysyl-[protein] = malonyl-CoA + N(6)-biotinyl-L-lysyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:54728"/>
            <dbReference type="Rhea" id="RHEA-COMP:10505"/>
            <dbReference type="Rhea" id="RHEA-COMP:10506"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:83144"/>
            <dbReference type="ChEBI" id="CHEBI:83145"/>
            <dbReference type="EC" id="2.1.3.15"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="13">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="13">Lipid metabolism; malonyl-CoA biosynthesis; malonyl-CoA from acetyl-CoA: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the AccD/PCCB family.</text>
    </comment>
    <dbReference type="EC" id="2.1.3.15" evidence="13"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00655">
        <property type="reaction ID" value="UER00711"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009317">
        <property type="term" value="C:acetyl-CoA carboxylase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003989">
        <property type="term" value="F:acetyl-CoA carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016743">
        <property type="term" value="F:carboxyl- or carbamoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001295">
        <property type="term" value="P:malonyl-CoA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01395">
        <property type="entry name" value="AcetylCoA_CT_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034733">
        <property type="entry name" value="AcCoA_carboxyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000438">
        <property type="entry name" value="Acetyl_CoA_COase_Trfase_b_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011762">
        <property type="entry name" value="COA_CT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041010">
        <property type="entry name" value="Znf-ACC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01039">
        <property type="entry name" value="Carboxyl_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17848">
        <property type="entry name" value="zf-ACC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01070">
        <property type="entry name" value="ACCCTRFRASEB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00515">
        <property type="entry name" value="accD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50980">
        <property type="entry name" value="COA_CT_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11 13" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="7 13" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="15" id="KW-0436">Ligase</keyword>
    <keyword evidence="2 13" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="10 13" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="4 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 13 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 13" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 13" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CoA carboxyltransferase N-terminal" evidence="14">
        <location>
            <begin position="22"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C4-type" evidence="13">
        <location>
            <begin position="26"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="26"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="29"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="QDV57042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="279" mass="30460" checksum="A46578825D613304" modified="2019-10-16" version="1">MATVESNSEAPNTKKRGIPEGLWIKCPGCLSSVYRKEVQRRLNVCPKCDHHLYVSAADRVEQVLDEGTFEAWDEELRPTDPLEFADRKRYAERLLAEQKRTGLVDAALTGTGMIRARRVAFGVTDSAFIMGSMGSVVGERLTRLIERATEQNLPLIIISGSGGGARMHEGILSLMQMAKVSAALARYHESGGLFISVLTNPTMGGVAASFASLGDLCFAEPKALIGFAGPRTIKATIGIELPEGFQTSEFLLEHGFIDRIVARDRLKSEIARVIDYCGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVD5</accession>
    <name>A0A518IVD5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Serine/threonine-protein kinase PknB</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">pknB_14</name>
        <name evidence="3" type="ORF">Mal33_30440</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="44"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="14"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="317" mass="35535" checksum="C94618C02828712A" modified="2019-10-16" version="1">MGLLDKIQSLIGKKKTEEGDSGAAAVPKSKQTKGSNSLDVEARFERMRSAVSGTMSNFITARDRQYNRVVGLKLCDAEKVATFEARFKGLKKPIEGAIAVQMQHPNVVETYEYGTTKQGQPYLVMEYVDGPGLLQVIQTRKEETLAGKRLSLIRQMAEGMKYVHEKGFIHRDICPRNFICSSDMDRIKLIDFGLTVPALPPYMQPGNRTGTPLYMAPEIVRRRQTDQRVDVFAFGVSIYTLCAFEFPWPVNDTTGKAALQHDTHPPIPILQFRPDLNPVLATAIMRCISPNVQDRMPSMEAFLRQIKGVRSELKSPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVM2</accession>
    <name>A0A518IVM2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">1,5-anhydro-D-fructose reductase</fullName>
            <ecNumber evidence="3">1.1.1.292</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">afr_6</name>
        <name evidence="3" type="ORF">Mal33_31420</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.1.292" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033712">
        <property type="term" value="F:1,5-anhydro-D-fructose reductase (1,5-anhydro-D-mannitol-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004104">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02894">
        <property type="entry name" value="GFO_IDH_MocA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GFO_IDH_MocA" evidence="1">
        <location>
            <begin position="6"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="GFO_IDH_MocA_C" evidence="2">
        <location>
            <begin position="137"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="348" mass="38498" checksum="53C22D72F767DE47" modified="2019-10-16" version="1">MSDRPVRFGLIGFGAWGQHHANAITVTEGAELVAIAARSDTSVAAAKEKYPDAAVYNDYRELVAREDLDFVDVVVPSHLHHAVATAVLQAGKHLLLEKPMGVSMEECDDMIRIANQQDRLFAVGHELRLSSMWGKAKELIDEGFIGDPLYALVELSRNPYRQGADGWRYDIDRVGSWILEEPIHFFDLARWYLERAGQPERIYATANSRQPGRPELQDNFSAIMHFSGGSYAVVSQTLAAFEHHQTAKITGTKGALWASWSGAQDRTRHPTFSLRGFDGNEVVTIPIDKPTGELFELEDQVARVVQAHRSGVPLHCNAEDGRWSVAMCLAAEASVRSGNIVSISDYIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVR1</accession>
    <name>A0A518IVR1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Inositol 2-dehydrogenase</fullName>
            <ecNumber evidence="8">1.1.1.18</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">iolG_7</name>
        <name evidence="8" type="ORF">Mal33_31740</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.18" evidence="8"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016798">
        <property type="term" value="F:hydrolase activity, acting on glycosyl bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050112">
        <property type="term" value="F:inositol 2-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008152">
        <property type="term" value="P:metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004104">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019546">
        <property type="entry name" value="TAT_signal_bac_arc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02894">
        <property type="entry name" value="GFO_IDH_MocA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10518">
        <property type="entry name" value="TAT_signal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0520">NAD</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GFO_IDH_MocA" evidence="6">
        <location>
            <begin position="40"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="GFO_IDH_MocA_C" evidence="7">
        <location>
            <begin position="182"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV57173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="487" mass="54103" checksum="6FB5F08211B43DA7" modified="2019-10-16" version="1">MENQGSHRRSFIKTSAAVAAAASVIQAPAPARAAGSNERLRIGFIGPGGRGFGAHVKKLAQLHKDGANIELVALAEVYSVQRDRVADYIEKETGFKPAKYVDYREMIEKENLDAVAIGTPDHWHAKQTIDALEAGLHVYCEKPMTKTVEESLKVVDAWRKSGKVMQVGVQSTSLPVWDEVRNLLQDGKLGKVLMYQTEYFRNSAQGQWRYYKLEPEMTPTNVDWKRWLGSDEGLAEEIPFDRAVYKQWRRFWPFGSGMYTDLFVHRTTAMLKATGLRFPARVVGAGGLYMEYDGRDVPDVATVAADFPEGVHGLVNATMCNQETRIQQLIRGHNGSFVFGNGEQFDGFDFVPERSQVTRIRDQKTERIATKPVADTTYAHFKNWIEACAAEEPMQCNNTPELGAAAIAVVTLGARSYREGTVFFFDGDSGKISTTDPGWAASWEKLSAARAPVKHIPGWRAGDTGSVLEEPEYMKLAGPWVDGKDPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVY5</accession>
    <name>A0A518IVY5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_32530</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="144" mass="15985" checksum="ED14E1DE516943CE" modified="2019-10-16" version="1">MIVTGKALGSRRPLFADWSIPIPPDDANGDGDGGLTLRDLIERIVVQQVSLFRKRQHDRQFLRALTAAEISDAVDRGKVDLGGSEVPIQNVDEEQAIHNAIQAFEDGIYLVVIDEQEQNDLDKQIFLNAESRITFIRLTMLSGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IW24</accession>
    <name>A0A518IW24_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">VWFA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_32980</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13768">
        <property type="entry name" value="VWA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="2">
        <location>
            <begin position="164"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="415" mass="45574" checksum="11E761BF7AD574CB" modified="2019-10-16" version="1">MPTTMNLAVQSQNESTSRANWRGYAISATLHAVLLLALAFVVLGESGVETFIVTAKQATARAEPLIAIPLEPAPAPEPQTSEAIELASPLPKLSLAPIPVDLPGRLASQRLGALSGSGQNVVTVAHAQPVTKTETKSKEKAADAVPSDSRRATFFGSHAYGNNFVFILDASPSMVGARYRRACDELIASLMKLEDSQSFYVLLFSWRTQLMFDGPLASIQFIPATDENVDRFRQWLYAQDVRKNNGTDPRVALDLAERLQPDAVFLLSDGEFNKPPRWNPSMPTRAMPQHSVARLVEMIYETIPLHCIAFEIAACEPGLRALSVLTGGSCRFVPPLRPDADQIFLTKLENQLRQVDPQGTGDSFRAQQTRLTIANWLVEKGFAEEAQDVIEVLADKQLPSRLQRKLESIQGKISE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IW64</accession>
    <name>A0A518IW64_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Outer membrane biogenesis protein BamB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_33420</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025666">
        <property type="entry name" value="PQQ-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018391">
        <property type="entry name" value="PQQ_beta_propeller_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002372">
        <property type="entry name" value="PQQ_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13360">
        <property type="entry name" value="PQQ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13570">
        <property type="entry name" value="PQQ_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00564">
        <property type="entry name" value="PQQ"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PQQ_3" evidence="1">
        <location>
            <begin position="73"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="PQQ_3" evidence="1">
        <location>
            <begin position="377"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13570"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="459" mass="51079" checksum="E2B0C2EC59C0CFAA" modified="2019-10-16" version="1">MMIVAFLEFASYQNRKTIPMRSASIARFLGCAGLILCGSFATAENWPQFRGPHFNGSSTETNLPTEFSRTENVRWSADLPGPSAATPAIWGDHIFVSSTSPGNDELLALCFDRKTGKQLWKHEIAKGTRQDTRSTFAAPSPVTDGKVAIFFFGNGELVAYDFDGKQQWKRNLQNEYGSFAFQWTFSTSPLIYQNRLIMQVLQRDTPVNGRGLADKVNESYLMAIDPQTGENLWRIIRPSKAQAESREAFTTPIPYQHDGREELLVIGGDAITGHDPATGKELWRWGTWNPQRIGHWRHVPSPVVGDETILICAPKKDPIYAVAAGGKGLLDDSSIRWISTDDRNLTSDVPTPAFYDGDFFVLSDLRKMLMRVEPKTGKVKWEVKTPGLKKYEASPTVADGKIYVVNFAGDVVIFDAETGEIINNVSMDDPSENNVRSSVVVSGGNLFIRVNHKLYCIGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IW76</accession>
    <name>A0A518IW76_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">PD-(D/E)XK nuclease family transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_33400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010106">
        <property type="entry name" value="RpnA"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01784">
        <property type="entry name" value="T_den_put_tspse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="309" mass="35109" checksum="5425044D6C336A47" modified="2019-10-16" version="1">MPLGIRPLVDFAFKKIFGSPENTLALIGLLNAVLKLQSPIREVTILNPFSYQEFEDAKQIVLDVRARDQSDRWLNIEMQVSIASGLLKRLTYYACSMYVDQLQSGDNYSNLNPAISICLLNKHLFTDSPQPHHRFQMLDRSSGRQLTDAIEVHTVELLKYNLEEAAIATASRIEQWVFFLLRAHEFDEKRLRELLPAIEFQQAIATVATISEKTEDRSMYDQREKALRDHEWRLAAAREEGEKIGEARGEKKGEARGEARGVVLGRIQILQSILSMTVSSEAALRDATTEQLIEIEADLQRIARARGQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IW97</accession>
    <name>A0A518IW97_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Arylsulfatase</fullName>
            <ecNumber evidence="4">3.1.6.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">atsA_25</name>
        <name evidence="4" type="ORF">Mal33_33610</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="PTM">
        <text evidence="1">The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.</text>
    </comment>
    <dbReference type="EC" id="3.1.6.1" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004065">
        <property type="term" value="F:arylsulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022173095" evidence="2">
        <location>
            <begin position="22"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase" evidence="3">
        <location>
            <begin position="25"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="modified residue" description="3-oxoalanine (Cys)" evidence="1">
        <location>
            <position position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR600917-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV57356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="481" mass="53934" checksum="A44A54995615F4B7" modified="2019-10-16" version="1" precursor="true">MLRLSLWLAAPLLLLSSSLVAAPKPNILLIVSDDQGYNDLGSLGNGIITPALDRLAAEGTRLTNFYVSWPACTPSRASLLTGRYPQRNGIYDMIRNEAPDYGKLYTPEEYDVTFERIGGMDLREVILPAALKPAGYKSGIYGKWDLGTLKRFLPTSRGFDDFYGFVNTGVDYFTHRRYGVPSMYRNLEPTVEDEGTYCTYLFEREALRFIDQHAGESPFFLYVPFNAPHNSSALEPEIRSTVQAPQKYKDLYPAVDPETQINKKYRYDAPATVTTRAARQRDYRAAVTCMDDAIGKMLDSLEQKQQLDNTIVIFFSDNGGSGGADNAPLRGRKGQTWEGGIRVPCIVRWPDGGVKPMQVNDAFLTSLELLPSLAAAAGIAPPEDVVLDGFDWWPTLRGDQPSPRKEMFWKRRDMIGARVGKWKWVDMSGKAGGLYDLQADPGERNNLAQSHPEVLKHVQSRYANWIAEMEASEPRGPFRDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWC1</accession>
    <name>A0A518IWC1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">GATase1_like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_34010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010768">
        <property type="entry name" value="GATase1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07090">
        <property type="entry name" value="GATase1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="domain" description="GATase1_like" evidence="2">
        <location>
            <begin position="400"/>
            <end position="563"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="761" mass="83034" checksum="1BA3E1CBA82FCFB2" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWE1</accession>
    <name>A0A518IWE1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Inosose dehydratase</fullName>
            <ecNumber evidence="2">4.2.1.44</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">iolE_1</name>
        <name evidence="2" type="ORF">Mal33_34240</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="4.2.1.44" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050114">
        <property type="term" value="F:myo-inosose-2 dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013022">
        <property type="entry name" value="Xyl_isomerase-like_TIM-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01261">
        <property type="entry name" value="AP_endonuc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="SSF51658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AP_endonuc_2" evidence="1">
        <location>
            <begin position="21"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="307" mass="34080" checksum="542136E407D2B713" modified="2019-10-16" version="1">MLQLGFVSAILPELSLDEVLAVAAEIGYDCVEVMCWPQGKAERRYAGITHIDTAALGPAEVDAIGALTQKHGVAISGLGYYPNPLAGDLAEAAAAVEHLHALIKACQQLSIPQLNTFVGRDWTKSVDANWPRFLETWRPIIAAAEQHGVRIGIENCPMFFTDDEWPGGKNLATTPAIWRRMFDAIPSDHFGLNFDPSHLVWQQIDHIQPVWDFADRIFHAHAKDVRVDRHRLNQVGIMANPLEYHCPKLPGLGEIDWGRFLSVLGDSGYAGPVCVEVEDRAYEGTLESRKAALRQSHDFLRNFIVKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWN0</accession>
    <name>A0A518IWN0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Planctomycete cytochrome C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_35110</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011429">
        <property type="entry name" value="Cyt_c_Planctomycete-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011444">
        <property type="entry name" value="DUF1549"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022655">
        <property type="entry name" value="DUF1553"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07635">
        <property type="entry name" value="PSCyt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07583">
        <property type="entry name" value="PSCyt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07587">
        <property type="entry name" value="PSD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022054617" evidence="1">
        <location>
            <begin position="31"/>
            <end position="1058"/>
        </location>
    </feature>
    <feature type="domain" description="PSCyt1" evidence="4">
        <location>
            <begin position="48"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="domain" description="PSCyt2" evidence="2">
        <location>
            <begin position="168"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="domain" description="PSD1" evidence="3">
        <location>
            <begin position="568"/>
            <end position="786"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV57501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1058" mass="116749" checksum="0AF1636105D4C75C" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWP2</accession>
    <name>A0A518IWP2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alkaline phosphatase D</fullName>
            <ecNumber evidence="3">3.1.3.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">phoD_2</name>
        <name evidence="3" type="ORF">Mal33_35140</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.3.1" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004035">
        <property type="term" value="F:alkaline phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07389">
        <property type="entry name" value="MPP_PhoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006558">
        <property type="entry name" value="LamG-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018946">
        <property type="entry name" value="PhoD-like_MPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038607">
        <property type="entry name" value="PhoD-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09423">
        <property type="entry name" value="PhoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00560">
        <property type="entry name" value="LamGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="LamGL" evidence="2">
        <location>
            <begin position="535"/>
            <end position="697"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="713" mass="78393" checksum="C2636ED53FEDA249" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWX0</accession>
    <name>A0A518IWX0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PilZ domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_36000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035438">
        <property type="term" value="F:cyclic-di-GMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009875">
        <property type="entry name" value="PilZ_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07238">
        <property type="entry name" value="PilZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PilZ" evidence="1">
        <location>
            <begin position="35"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="138" mass="15541" checksum="1A69F55B297B371D" modified="2019-10-16" version="1">MLGEHLVAGEQLLGADNDLRALEELCRTTSHESQRVAERRRLDTPVQIQPGNSRERGAWKLAGKLRDLSDTGCGIMTNKPLMVGDVYWLSTTDPATQLGSFFARCVRCRMIREGSFEQGFTFFSNPRQDRSNPPQPML</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IX72</accession>
    <name>A0A518IX72_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">L-ribulose-5-phosphate 3-epimerase UlaE</fullName>
            <ecNumber evidence="2">5.1.3.22</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ulaE</name>
        <name evidence="2" type="ORF">Mal33_37020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="5.1.3.22" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034015">
        <property type="term" value="F:L-ribulose-5-phosphate 3-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013022">
        <property type="entry name" value="Xyl_isomerase-like_TIM-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01261">
        <property type="entry name" value="AP_endonuc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="SSF51658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AP_endonuc_2" evidence="1">
        <location>
            <begin position="73"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="337" mass="37746" checksum="090BDD452740A79A" modified="2019-10-16" version="1">MQPESSLKRRDLLTYAAFGSAAWAVASQADGAGSTAVQGESTAPPRPRYAMKKSINLWAFPYPDKMSLRQCMELAKAAGFDGIELNYDLDSELSPKSGTKEFHAIRRMADEIGIAISGVCSFLFWPFPLTSNDPAERARGMELAGKMTQAAHDLGTENLLVVPGAVHMPWRADHDPTPNDVCDRRAREAIGKLLPQAEKLNVSLNMENIFFNGFLMSPMEMADFVDSFSSEHVKVHFDTGNIMEYQFPEHWIPILGKRIKNVHLKEFTKKGSDHSLEAFRPLLDGTTNWPAVLASFDQIGYDSYLTFEYFHPYQHFPEALVYQTADSLDRMLGIKQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXG2</accession>
    <name>A0A518IXG2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Stress response protein NhaX</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">nhaX</name>
        <name evidence="3" type="ORF">Mal33_37930</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal stress protein A family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006015">
        <property type="entry name" value="Universal_stress_UspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01438">
        <property type="entry name" value="UNVRSLSTRESS"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Usp" evidence="2">
        <location>
            <begin position="2"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="Usp" evidence="2">
        <location>
            <begin position="165"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="321" mass="35320" checksum="A73F0C0DA63CDEC3" modified="2019-10-16" version="1">MKILFATDGSCYAAGAARFVRHLQSKDPMELTVLTVSYTPENTSSPSVQPWLPEWRRREHERIDQHHAELRETLKSINGKVTMELAEGNAARCILERARELDADLIVMGARGHSTLERLLLGSLSDSVATHADCSVLIVRPPELHGVAAGSDPCPEPAADEIPVRKIELAYDGSASSKEAVNELMRFQWPAETEVSILSVIPTFDFYGQEYGLMVEPHGKEEHQRVQALCEKVISSLSRSIKNVDSQTVMGDHVGDAIVRAADENQSQLIVLGDNGHGLIGELLLGSTTKYVLRHAHCSVWISRHHRTQAEKVAEAAVQPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXH0</accession>
    <name>A0A518IXH0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_38040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010869">
        <property type="entry name" value="DUF1501"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07394">
        <property type="entry name" value="DUF1501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="465" mass="51340" checksum="299BCC4CD6F2147B" modified="2019-10-16" version="1">MNSPFDPTTSLLSRRSILRSAGGGFGMLGLTDLLSQDASASSNAEKLGLPHFPAKAKRVIFLFMSGGPSQLDTFDPKPDLHKYEGQRPAAVDIRTERPTSGLSASPVKFTPAGESGIPFPEYFPRLAKHADEMAIIRSMYTDNPNHAPALCLMNLGAMTPTRPSVGSWLTYGLGSENQDLPGYLALCPGLPVVGPKLWGNAFLPGEFQGTYIHTKKTSPEAMIPHLRNTELSPKLQKEQLDLVAAINRQHMEQRTDAVDLETRISSMELAYRMQFEAMEAFDISRETQATRDAYGTSEFAESCLLARRLSEHGVRMVQVYYGNRQPWDTHSNHQKLNGKLCKDIDGPIAQLLTDLKQRDLLDETLVVWGGEFGRTPTVEGGSGRDHNPYGFSMWMAGGGIKGGTIHGATDDFGFRAVQDKVHVHDLHATIMHLMGIDHQKLTYHYSGRDFRLTDVHGEVVHNIIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXK9</accession>
    <name>A0A518IXK9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_38440</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021920014" evidence="2">
        <location>
            <begin position="26"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="272" mass="28979" checksum="7C91C2B23ED26D60" modified="2019-10-16" version="1" precursor="true">MNSATIAPLAVAGFLIASLPITGLAQPESPALNANPFAARPPQNQAPLFQGPSTTEDPTPGDLEKSAKMIQPKNSASDVDRFSSEAIEEALRRPVEAMFSDEPLENIIEILADKAGIPIRIDRRGLDDLGLTTDIPVTTAIKRASLEAALSIILSDLDLTHTIANEHLVITSVEAAESQLITRIYWSGETGLQADRNAIDLITATVTPDTWEELGGPSVIRGIETESGSSSGLVVTTTHFTHRKLQQLLDMIAAGAKEKVIAMEMKSPGLTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXN8</accession>
    <name>A0A518IXN8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">MurE-like ligase</fullName>
            <ecNumber evidence="3">6.3.2.7</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_38510</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="6.3.2.7" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047482">
        <property type="term" value="F:UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-L-lysine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004101">
        <property type="entry name" value="Mur_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035911">
        <property type="entry name" value="MurE/MurF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02875">
        <property type="entry name" value="Mur_ligase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63418">
        <property type="entry name" value="SSF63418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mur_ligase_M" evidence="2">
        <location>
            <begin position="113"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_C" evidence="1">
        <location>
            <begin position="330"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="506" mass="53730" checksum="146F01BE0BA6F0C3" modified="2019-10-16" version="1">MDVAKRIGSQDVSLRQLFPAARMISTPDMTVRRCSADASDCSPGDVFVAGIDDTPADEAAAEAVAGGAIGIITEQLLPVSVPQCIVADAREAYAHLVSELAGKPSQQMLSIGVAGIDGKTSTTLMVAAALRKSGLRVAYNCDLGRSDGIIQDVPRRPLSDAQDLTDWYADASDSGCQVAVVELSEAMLRSHAADGTSFDIMILSGDSDHAYLKSAQGGSLFSEAISHVRSKGLVILNESNAVAAQAAESSDLSILTYGTSQEADVVGRIMERHAGETTFLITAGDTTAAVRSRMTGDWMFHHQLAAAATALVMDFPLETVAAGLSAMEKIPGRMQRVASYTGPQIVLDDADCPERVMATINTLRKELPRRGKIWCIAACDHRRTATHAANLGYITERCSDHLVLTSGVSGTDEFLSLVHEMLDGVVDPAKPQLIANREAAIQWTINKATPNDLIVILGGWCPDSPRTIRAAIDADTKLAEQALERVEAIDDSEPVILPHPALLASM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXR8</accession>
    <name>A0A518IXR8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_38990</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="92" mass="9941" checksum="92511BBE6E393460" modified="2019-10-16" version="1">MRFEQAMKSVAVAFAGAATKLRQPTRRCAILIENAGQAETLRLAGPILWASREETKANCGRIRMIGPSKSLPITAEMSVAIERNARASATLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IY03</accession>
    <name>A0A518IY03_9BACT</name>
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            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="1" type="ORF">Mal33_39800</name>
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    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011453">
        <property type="entry name" value="DUF1559"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07596">
        <property type="entry name" value="SBP_bac_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="306" mass="32790" checksum="9BF848965C012EBC" modified="2019-10-16" version="1">MIPQNKRISLRRGFTLVELLVVIAIIGILVGLLLPAVQAAREAARRMACSANYKQVALAIHNYHDTHRTFPLGGGITGGCSGLTGPHMFSWGVHTLPFIEQSARYDAIEFNVDNYVTGYGPNHDPDTALGPIPVYLCPSNPQSDTMVNTGLAALVDSFARTDMAGVADSRDWRCNSSGTTGVRPRSDGNGIFYGGSSTKFRDIIDGTSNTLLIGEVTGDLNPANTLNANTYSLYDVFDTSTGINGPFTLPGGGTFNYRPQGFSSYHPGGAHFALADGSVRLFTETIDQTLLYGLTTRLGGEVLQEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IY36</accession>
    <name>A0A518IY36_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ferrous iron transport protein B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">feoB</name>
        <name evidence="4" type="ORF">Mal33_40100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015093">
        <property type="term" value="F:ferrous iron transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01879">
        <property type="entry name" value="FeoB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011640">
        <property type="entry name" value="Fe2_transport_prot_B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030389">
        <property type="entry name" value="G_FEOB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011642">
        <property type="entry name" value="Gate_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07664">
        <property type="entry name" value="FeoB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02421">
        <property type="entry name" value="FeoB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07670">
        <property type="entry name" value="Gate"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51711">
        <property type="entry name" value="G_FEOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0406">Ion transport</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
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        <location>
            <begin position="243"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="299"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
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            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="377"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="409"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="470"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="606"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="637"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="domain" description="FeoB-type G" evidence="3">
        <location>
            <begin position="19"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV57994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="663" mass="71980" checksum="EAE89B7497C575A1" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYL6</accession>
    <name>A0A518IYL6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_41940</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041289">
        <property type="entry name" value="Bact_RF_family3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18845">
        <property type="entry name" value="baeRF_family3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="386" mass="43182" checksum="B4DF86A74578E110" modified="2019-10-16" version="1">MIQSFNRDQVKRLSGLPGTPHVTLFLPASPEHALASDGSIGLGQLIEKSHQQLAQFWMSSTDANDFLRPLFDLQEDPQFLAARSGGVAIYLSEDVFEIVPGYEESDSRAIVAGTFCLRPMLLTENQFADFYLLTISKQKLAFYRATLSEITQIQNAGFPVSFENAVRSAAREPMLVHTGFEDLTRTAAVDIDEIEEGIDPLAPAFIEYIQQVDEAVCAYLHDRSGFLILAGSEAETDLYREHSVCTQRVGKVLTGNIDQYSPEKLLREAMPLAVDQLQQQRDSDAREFRERQRPVTLDAREILCAAQVGRIDTLFFDRDATLYGSFHRERNVLQESGQPPQGRPREECRDLIESAMVQTIIHGGRIHAAPASDMPVRAKMAATLKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYP7</accession>
    <name>A0A518IYP7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative PIN and TRAM-domain containing protein</fullName>
            <ecNumber evidence="3">3.1.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_42300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
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        <property type="project" value="UniProtKB-KW"/>
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    </dbReference>
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    </dbReference>
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            <end position="62"/>
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    <feature type="transmembrane region" description="Helical" evidence="1">
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
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            <end position="120"/>
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    </feature>
    <feature type="domain" description="PINc" evidence="2">
        <location>
            <begin position="143"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="340" mass="37249" checksum="2066F62481DBC238" modified="2019-10-16" version="1">MGLLLLRAVFLLVAGGISALINYAVQAANSSLQVTTPAWVPWANLAIVMGLALAVIAIDVFVPNKRIDAISSIYFGLLVGVLLTYVLTIALAPLLAEHLQTPVRLVTGMVLCYICISLLLQTKDDFRFIIPYVEFVREVKGFKPLILDTSVVIDGRIEDLVSTGIFDNQLIMPRFALSELQGIADSSDKLRRARGRRGLDVLNRLRANDAVDLQIFDRDLPEFAGQAVDLKLVLLAKHLEGKVVTGDFNLNKVAKIHNVPVINLNEIANSLKPMYLPGEQFQLKVIKAGEGQDQGIGYLEDGTMVVVEGGRDKISKDLMVTVTSTLQTSAGRMIFTRHDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
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    <name>A0A518IYT9_9BACT</name>
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        </recommendedName>
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    </gene>
    <organism evidence="3 4">
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        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Pirellulaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
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                <person name="Spormann A.M."/>
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                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
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    </reference>
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        <property type="project" value="UniProtKB-KW"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="33"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="2">
        <location>
            <begin position="187"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
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    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="640" mass="71926" checksum="536C0880B4FA4BCF" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYU1</accession>
    <name>A0A518IYU1_9BACT</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
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    <organism evidence="2 3">
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        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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    </organism>
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="project" value="UniProtKB-KW"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
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            <begin position="473"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="745" mass="81365" checksum="4FD025013F472EA1" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ73</accession>
    <name>A0A518IZ73_9BACT</name>
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        <submittedName>
            <fullName evidence="6">ABC transporter ATP-binding protein YtrB</fullName>
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        <name evidence="6" type="primary">ytrB</name>
        <name evidence="6" type="ORF">Mal33_44030</name>
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    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="11"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="301"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="43"/>
            <end position="50"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV58385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="321" mass="35168" checksum="29B2817976A7F8D1" modified="2019-10-16" version="1">MNASQTVGVAVDVQNLSRKFRGNEALRDVNLQIPSGSIFGLVGLNGAGKTTLIRHLIGALVAKHGQVRVLGQDPVADPVGVLRRIGYLSEEDSLPQWLRVGELIDFSKAMYPTWDDAYAAELCEMFSLSRTSRLQSLSKGQRARAGLLVAIAHRPELLILDEPSSGLDPIARSDILEAIIRTVGEDGRTVLFSSHLLDEVARVCDTVALMSAGRIVERRTIEDLQSRYCEIICRENFADGDSPRLPAAFGWQRSGGEWSAVVETQRLEASLLSGDLQLLNRYEITLERWFTARANTSADDPLAIEEDESGPQQAIASGEIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZD8</accession>
    <name>A0A518IZD8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HDc domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_44810</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045509">
        <property type="entry name" value="HD_assoc_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19276">
        <property type="entry name" value="HD_assoc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HDc" evidence="1">
        <location>
            <begin position="65"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="447" mass="50358" checksum="88B9CAA164177D87" modified="2019-10-16" version="1">MNRQEMLSQIPELLSFAASPRVVRIPPEMNVPMTDRAARLLDTPPLRRLSQVSQLGLVGLVYPGATHSRMEHSLGVYRNALMFLQRLVTTKRFAEVVDPRGAERFLLASLLHDVGHWPFCHPIEDMRLPGVPRHEQRARRIIGDAEIADRIRNDWQIEPDEVCDLLDGKDLSDENQALSSLLSGPIDVDKMDYLIRDSLHAGVPYGRNFDTGRLIGSLAIHPSRPRLAITDKGRTAAEMMVFSRYIMFSEVYWHPTVRSATAMLQRAIYQLHERLDMDSMCELTDAPWIERLLMASAGTDVQWLTQGLFGPKRRLFKEIGQFSVLDSPQIHASLAGRPYPWLVRCSESFARLASAAIGRRVGPTHVLIDAPPQKLEVDINVDVVDEQGVVRTLGDVSPVAAVLARQQFDNFVKRVRIFVCPELRDSITPQQAREILEAAVEQTPDAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZT6</accession>
    <name>A0A518IZT6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional activator protein CopR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">copR</name>
        <name evidence="5" type="ORF">Mal33_46270</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="4"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="4">
        <location>
            <begin position="126"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="126"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV58603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="229" mass="26405" checksum="33A3CA57613F2C85" modified="2019-10-16" version="1">MSVRILVVEDDPGISDFLIRGLNEEGYTAELAQEGRHAWLRLQSETWDLVILDWWLPGEDGIQILQRFRQKNRTTPVLFLTARDGVNERVTGLDAGADDYLTKPFAFEELLARVRALLRRPSQSDSVYLEYRDIRIDLAQQRATRADVPLDLTAKEFSLLSMFLRHPGRVLSRTRIYETVWDENFDGLSNTLEVHVKELRRKLETLGPRVIQTRRGQGYILESQDAGHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J099</accession>
    <name>A0A518J099_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RNA polymerase sigma factor CarQ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">carQ_2</name>
        <name evidence="4" type="ORF">Mal33_47920</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014331">
        <property type="entry name" value="RNA_pol_sigma70_ECF_RHOBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02989">
        <property type="entry name" value="Sig-70_gvs1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="2">
        <location>
            <begin position="14"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="3">
        <location>
            <begin position="112"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV58767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="192" mass="21718" checksum="1CCAD5891DF1BC3C" modified="2019-10-16" version="1">MSDSRSAFEDLLQQAQGPLLDYLIRLTGSVHVAQDLLQAANVTAIEKQSSFHAGTDFAAWIRQIAKNHYRNAIRKQAVSKTVLLVDDGLHDVIERRHRERIEKQRREADWDRLQDCLQTLPGHQRELVQRFYIDGQSLNHLAKTTGRNANAIGQTLHRARRALIECVKFAGDEPPQVASIFGCEAQQGAESR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0A3</accession>
    <name>A0A518J0A3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Bacterial type II/III secretion system short domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_47960</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="NolW-like"/>
    </dbReference>
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        <property type="entry name" value="NolW-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03958">
        <property type="entry name" value="Secretin_N"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
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        <location>
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            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022015692" evidence="2">
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            <end position="984"/>
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    </feature>
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        <location>
            <begin position="419"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="domain" description="Secretin_N" evidence="3">
        <location>
            <begin position="646"/>
            <end position="753"/>
        </location>
    </feature>
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        <location>
            <begin position="766"/>
            <end position="871"/>
        </location>
    </feature>
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            <begin position="32"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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            <begin position="523"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="812"/>
            <end position="833"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="904"/>
            <end position="984"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
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            <begin position="533"/>
            <end position="571"/>
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    </feature>
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        <location>
            <begin position="573"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="904"/>
            <end position="934"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF03958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV58771.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="984" mass="102228" checksum="96596AEAD0BAAC31" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0K0</accession>
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        <alternativeName>
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        <alternativeName>
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        </alternativeName>
    </protein>
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        <name type="scientific">Rosistilla oblonga</name>
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            <taxon>Planctomycetia</taxon>
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    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
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                <person name="Rohde M."/>
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                <person name="Jogler C."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <comment type="catalytic activity">
        <reaction evidence="6 7 8">
            <text>alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate</text>
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    </comment>
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    <comment type="pathway">
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    </comment>
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        <subcellularLocation>
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        </subcellularLocation>
    </comment>
    <comment type="similarity">
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
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        <property type="project" value="InterPro"/>
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        <property type="term" value="F:glucose-6-phosphate isomerase activity"/>
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        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="project" value="UniProtKB-UniRule"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Phosphoglucose_isomerase_CS"/>
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        <property type="entry name" value="SIS_PGI_2"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="G6PISOMERASE"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="P_GLUCOSE_ISOMERASE_1"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
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        <source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="QDV58871.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="584" mass="65065" checksum="F7BA562D44DD1D7B" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0T4</accession>
    <name>A0A518J0T4_9BACT</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
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    </protein>
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        <name evidence="1" type="ORF">Mal33_49810</name>
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        <name type="scientific">Rosistilla oblonga</name>
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
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                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
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                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
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                <person name="Amann R."/>
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                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="1 2">Mal33</strain>
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        <property type="entry name" value="YHJQ-like"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="110" mass="11934" checksum="CF0A892E6965DB39" modified="2019-10-16" version="1">MSAATASKQECIKNCQECQTTCADQLTSHCLVEGGEHVQQQHVQRMLDCIAACKACIDFMSRNSEYHALYCKACAEVCKACADSCEQVGDMDQCVACCRKCVQSCSAMAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0X3</accession>
    <name>A0A518J0X3_9BACT</name>
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        <recommendedName>
            <fullName evidence="4">UDP-glucuronate decarboxylase</fullName>
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    </protein>
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        <name type="scientific">Rosistilla oblonga</name>
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    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Nucleotide-sugar biosynthesis; UDP-alpha-D-xylose biosynthesis; UDP-alpha-D-xylose from UDP-alpha-D-glucuronate: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.35" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00796">
        <property type="reaction ID" value="UER00771"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048040">
        <property type="term" value="F:UDP-glucuronate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042732">
        <property type="term" value="P:D-xylose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033320">
        <property type="term" value="P:UDP-D-xylose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044516">
        <property type="entry name" value="UXS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43078">
        <property type="entry name" value="PTHR43078"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="7">
        <location>
            <begin position="5"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV58990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="322" mass="36271" checksum="F3A8057E8F20B700" modified="2019-10-16" version="1">MQRILVTGGAGFLGSFMCERLVAEGHDVICLDNFFTSQKTNVAHLLGKPNFELIRHDITLPIFLEVDQVYNMGCPAAPGHYQYNPIKTMKTSVMGAINMLGLAKRCGARILQASTSEVYGDPEEHPQTESYRGNVNPIGPRACYDEGKRAAETLFMDYHRMNKVDVRIVRIFNTYGPRMHPYDGRVVSNFIRQALQNEDITIFGDGQQTRSFCFRDDLVDAIIRMMNNTEGFVGPVNIGNQGEFTIRELAELVIELTGSKSKLIQQPLPADDPTRRKPDITLATKHLGWTPTTPLRDGLAKTIEWFQSIDLNDYRPPTPNYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0Y1</accession>
    <name>A0A518J0Y1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Excinuclease ABC subunit C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_50240</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000305">
        <property type="entry name" value="GIY-YIG_endonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035901">
        <property type="entry name" value="GIY-YIG_endonuc_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01541">
        <property type="entry name" value="GIY-YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00465">
        <property type="entry name" value="GIYc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82771">
        <property type="entry name" value="SSF82771"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50164">
        <property type="entry name" value="GIY_YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022187650" evidence="1">
        <location>
            <begin position="26"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="GIY-YIG" evidence="2">
        <location>
            <begin position="198"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="286" mass="31937" checksum="729ED2465F1E8CC0" modified="2019-10-16" version="1" precursor="true">MTGEAAVRQLPAMLLLFCLPGIATAQTATALPAIVVEAFAKTSNGWSSDEVLLDDIRRERFLAAVRTRQPDADEATCNLMLLKLRKAGKLTVKATRRGKPADGRVLPIAEIAARTIMEKFDVATDTMIADPTLRKAFDAAALIVDPDVSLYDVRKAAFQLRKSRRLKPELVLRVADWDKQVVVKPLPEVRSNLKLVPTLPGIYLFRDQTGYIYIGEAVNLRVRLTQHLNDSDRRSLAAYIEQTAGEGLSIEWHAFPKDSPARQVAVRRAYESELIRSRNPRLNVRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J137</accession>
    <name>A0A518J137_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_50790</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007069">
        <property type="entry name" value="Transposase_32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026889">
        <property type="entry name" value="Zn_Tnp"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04986">
        <property type="entry name" value="Y2_Tnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14319">
        <property type="entry name" value="Zn_Tnp_IS91"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn_Tnp_IS91" evidence="2">
        <location>
            <begin position="8"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="373"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV59054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="397" mass="45194" checksum="F890F3134C3A5448" modified="2019-10-16" version="1">MGITLQQVFRQHFDAVAAKRRLSSDMYRAAWAVRHCRTRELGGHVNSCPVGHVCQVAYNSCMHRSCPQCAWLPREQWLAGWKRRLLPTPHHHIVFTVPHSLNELWRYNKVQFSKLLFDAAFETLHELLADPKYLGAVPGILAALHTWNQKLDVHVHLHVLVTAGGLGPRKQWVKSQRKCLLPRKVLMIKFRGKFRAFLRERVAKRLLRLPPQLSSAGFQGLLQSVGSLPWNVKIHEAYLRGESVAIYLARYIKGGPMGRARLLEIRDGKVEFRYRLSALEGGDGKRQGIAQLPVESFIRRWLEHVPPRRMQTVRGTGLYCGNQHSQLTTARESLGLRPLEPLPQQRMTWQERCVASGYTAASRCKQCGATLVSHSPFPAGRGPPRSAFRRRFPGQVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J153</accession>
    <name>A0A518J153_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">D-alanyl-D-alanine dipeptidase</fullName>
            <ecNumber evidence="3">3.4.13.22</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">vanX</name>
        <name evidence="3" type="ORF">Mal33_50920</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>D-alanyl-D-alanine + H2O = 2 D-alanine</text>
            <dbReference type="Rhea" id="RHEA:20661"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57416"/>
            <dbReference type="ChEBI" id="CHEBI:57822"/>
            <dbReference type="EC" id="3.4.13.22"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="3.4.13.22" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016805">
        <property type="term" value="F:dipeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1380.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000755">
        <property type="entry name" value="A_A_dipeptidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009045">
        <property type="entry name" value="Hedgehog_sig/DD-Pept_Zn-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01427">
        <property type="entry name" value="Peptidase_M15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55166">
        <property type="entry name" value="SSF55166"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="3" id="KW-0224">Dipeptidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV59067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="284" mass="32367" checksum="A726BF61DFFE3131" modified="2019-10-16" version="1">MKTTSAVPSRRDYWAQQMQLGYDLIQQIIPFEVHECGEGFASLPDAAERAGIELQFSESKIAGELERVFFIREGLVNKLMAIGRAMNDRGWILKIEDGYRCQDMQSQLVRKPELFDAILKKCIWENDGQLPPTELVFRRATVLIANIPKIGTHMSGSAVDISVFRRDDGSEVWRGNPYLEMSERTPMRSPFIEADDLQNRLEITAIMEDHGFMHFPFEFWHYNQGDAMGNILSGHAVPARYGPVHWDPQTNRVTPYDEPLRPLNPLDAIEQEIAAATQRATTSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J163</accession>
    <name>A0A518J163_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptidase A2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_51080</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010496">
        <property type="entry name" value="3-keto-disaccharide_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001995">
        <property type="entry name" value="Peptidase_A2_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06439">
        <property type="entry name" value="DUF1080"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50175">
        <property type="entry name" value="ASP_PROT_RETROV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022040031" description="Peptidase A2 domain-containing protein" evidence="1">
        <location>
            <begin position="26"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A2" evidence="2">
        <location>
            <begin position="49"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV59083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="266" mass="29630" checksum="283F4B17C79B85EC" modified="2019-10-16" version="1" precursor="true">MNNLHPLRLIPLALTVFLAVESATAKEPGETLEFQPNQTHLPVEPPADAIVLFDGGADVGFLNKHGEPIDWPVVDGTLESSGGQKANHIVSKWHFRDADIHAEFMLPEDGPGNSGLYIHGNYEMQIIHSAEKKRLGDSDMGAIYGFSKPLVPAERGRGVWQVYDIRYRAPRRDSDGKVTANGTITAWLNGQLVQDAAEFGEPRSVYHPYRSGTTDYLKAIWKKQIATTTGPLFLQDHGDAVRFRNVWIRPLDNLAYRYDLVPTDSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1B5</accession>
    <name>A0A518J1B5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Planctomycete cytochrome C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_51600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011429">
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    </dbReference>
    <dbReference type="InterPro" id="IPR011444">
        <property type="entry name" value="DUF1549"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022655">
        <property type="entry name" value="DUF1553"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07583">
        <property type="entry name" value="PSCyt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07587">
        <property type="entry name" value="PSD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PSCyt1" evidence="3">
        <location>
            <begin position="47"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="domain" description="PSCyt2" evidence="1">
        <location>
            <begin position="153"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="domain" description="PSD1" evidence="2">
        <location>
            <begin position="420"/>
            <end position="668"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV59134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="688" mass="77122" checksum="EB4DA8E349869B0A" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1H7</accession>
    <name>A0A518J1H7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF1080 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_52030</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="3-keto-disaccharide_hydrolase"/>
    </dbReference>
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        <property type="entry name" value="DUF1080"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021935340" description="DUF1080 domain-containing protein" evidence="2">
        <location>
            <begin position="25"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1080" evidence="3">
        <location>
            <begin position="51"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="242"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF06439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV59175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="263" mass="29230" checksum="2AADBA888B70EF1B" modified="2019-10-16" version="1" precursor="true">MKRLNQTVLYTAALAVSLAPLASADEYLNGITWQPPTVVTPGDANKPPSDAIVLFDGTDLSAWKGTDNWKIVDGAAVSGKGDIRSKQAFGDCQLHIEWSAPTPATGNGQGRGNSGLFLMNTYELQILDSYDNETYHDGQAGAIYKQTPPEVNATRPPGEWNVYDVIWTAPRFNEDGTLKSPAYITALHNGVVIQNHFELKGDTPYHRPPEYKQHAERLPIRLQDHGNPVRFRNIWVRELQPAQGEQEREPFLRDGKGNEKPVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1P5</accession>
    <name>A0A518J1P5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF547 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_52790</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006869">
        <property type="entry name" value="DUF547"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04784">
        <property type="entry name" value="DUF547"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021968931" description="DUF547 domain-containing protein" evidence="1">
        <location>
            <begin position="26"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="DUF547" evidence="2">
        <location>
            <begin position="99"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV59251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="276" mass="31057" checksum="D59A70AC4B2A9F03" modified="2019-10-16" version="1" precursor="true">MIHKTTKLAIFAFLTFPAISSPAWAGSAVYLGTRVAQSRQVSIDKIDHAAWDAITRKYVDTNGMVNYRGLKASAADMQALARYLNLLSTANPSLPASPDATLAFWINAYNAVTVHGILREYPTTSIRNHTAKLWGYNIWKDLQLYVGGKPYSLDQIEHEVLRKKGDPRIHFAIVCASIGCPRLLNEAYVPDRLQEQLQLNAKDFFARSQNFRYDPANRRMQLSSILDWFGEDFGGNQAAQLKRIAEWLPSQTAQAAARQNAVSVSYLDYNWNLNSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1Q2</accession>
    <name>A0A518J1Q2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">30S ribosomal protein S1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rps1</name>
        <name evidence="3" type="ORF">Mal33_52900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035104">
        <property type="entry name" value="Ribosomal_protein_S1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10724:SF7">
        <property type="entry name" value="PTHR10724:SF7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00681">
        <property type="entry name" value="RIBOSOMALS1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="S1 motif" evidence="2">
        <location>
            <begin position="202"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="2">
        <location>
            <begin position="278"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="2">
        <location>
            <begin position="365"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="2">
        <location>
            <begin position="450"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="522"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="524"/>
            <end position="558"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV59262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="573" mass="61312" checksum="37B71AFE46795F81" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1Q8</accession>
    <name>A0A518J1Q8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sporulation initiation inhibitor protein Soj</fullName>
            <ecNumber evidence="2">3.6.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">soj_3</name>
        <name evidence="2" type="ORF">Mal33_53030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.6.-.-" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025669">
        <property type="entry name" value="AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13614">
        <property type="entry name" value="AAA_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_31" evidence="1">
        <location>
            <begin position="141"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="419" mass="45945" checksum="07A1D892937F831E" modified="2019-10-16" version="1">MTSPRILIHRTDGSLDEELRNAMASAPNVHPVFHFQSDLRGTIGAAKDLQPSIVILEIGEDFETLKTLVEEAIAAAPDATIVGVYDVHRLPASSTESSMMMRALRLGVEDFLRRPVAGSDLRQVLQRRLAPRRKSHRADGKLISFISNKGGVGKSTAAVNVAVTLAMRYPDRVALIDSSLQMGVCATQLDLSPDTTLVDAWQQRDRLDETLLAQLMTVHESGLHLLAAPENAIEASEIDDSFLSRILLMARRSYDFVIIDTFPLFDRTVMAVLDLCDQAVIVVENVVPTLQTVRGFFSLLDEVEFPQHRQRVLLNRYSTRAGGPRATDVGRYLGRNPDYVIPHDQRVILAANTGRPFVLNATRWNKAAAAIRTLADDLETFAVAPADGLPLAAVAAPQRTAADSIDSNALEDRLGGELR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1U7</accession>
    <name>A0A518J1U7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_53310</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011467">
        <property type="entry name" value="DUF1573"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07610">
        <property type="entry name" value="DUF1573"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="376" mass="40932" checksum="AEAFE3B9021E2229" modified="2019-10-16" version="1">MRSRDTVSVALLSGKGSETVFTGAVKCWLETEGFDHKHFGWGFETMNTLKVRGVCGLMLIALVAPQAGAVEWADNMFPVKKHEFGTVAVAAKTEFRFPFKNLYKEDVHVSTVRASCGCTTPIIENHTLKTGETGHILARFNTGSFHGKKGATLTVVIDKPYYAEVQLRVDGYIRRDIVFNPGQVEFGSVMQGESVHKEIGVTYAGRSDWKIVEVQSPSPNVAAAFEEVSRNGGRVSYKLNVAFDGAAEPGQAHTNIVVITNDRAMPRVPLEVTYEVRPAVIVSPQVMAIGNLKPGESSEQRLVVRSDKPFRLTDIKAEGFSIEYKANAESKKMHVLPLKITAGDKAGSMSQRLIVHTDLPGDLTGSALVAGQIVAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1Z6</accession>
    <name>A0A518J1Z6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_53920</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="82" mass="8705" checksum="F5F63ACC2E10B9C8" modified="2019-10-16" version="1">MSGTSKNPKQNGTSAVGDFVRGHANQAAHAASEASQECSNYLVAQPAKDLLGLAKDYARDKPDVAALWCFGLGLFVGWKLRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1Z8</accession>
    <name>A0A518J1Z8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_53900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
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            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
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                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
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                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
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                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
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                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
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                <person name="Pohl T."/>
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                <person name="Galperin M.Y."/>
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                <person name="Devos D.P."/>
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                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
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        </source>
    </evidence>
    <sequence length="343" mass="38334" checksum="EEB3E1E9B77A8470" modified="2019-10-16" version="1">MICDAALLPLLNSPLPLAVAQMTTSTFWLLGVVVAVLAILLLTGRLLERRQSSMMNPALLQRFNHRVRVWLMMSAILVFAFLMDQFIRGVTVLLFGFVSFWALREFVTMTPTRRGDHRTLFWVFFIFTPLQYVLIALGPAYYGLYSIMIPVYGSLFIPARNALAGDSKRFLERTAKIQVGLLICVYSLSYAPAMLDLNLSSSRKVEWDGSPVSLLFFFILIAQIADVLQQAWNRFAGVHVIAKEINASRTWEGLLGSIVSTGAIGAALWWATPFEWYEAAVMSMIVAMMSSAGTMTLSAIKRDRGVTDTGTLVQGHAGLLDRIDNVCFAAPVFYHLTRYFFSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J2F4</accession>
    <name>A0A518J2F4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Serine/threonine-protein kinase PrkC</fullName>
            <ecNumber evidence="5">2.7.11.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">prkC_16</name>
        <name evidence="5" type="ORF">Mal33_55490</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.11.1" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="416"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="510"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="542"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="575"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="623"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="654"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="678"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="4">
        <location>
            <begin position="82"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="357"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV59514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="709" mass="77836" checksum="FED276AD9B25B4BA" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IM82</accession>
    <name>A0A518IM82_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Caspase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_01480</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029030">
        <property type="entry name" value="Caspase-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52129">
        <property type="entry name" value="SSF52129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="86"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="807" mass="88726" checksum="DDE04DD3A929F163" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMF3</accession>
    <name>A0A518IMF3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Iron-sulfur cluster carrier protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ylxH</name>
        <name evidence="5" type="ORF">Mal33_02160</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Mrp/NBP35 ATP-binding proteins family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140663">
        <property type="term" value="F:ATP-dependent FeS chaperone activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02040">
        <property type="entry name" value="Mrp_NBP35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019591">
        <property type="entry name" value="Mrp/NBP35_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000808">
        <property type="entry name" value="Mrp_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044304">
        <property type="entry name" value="NUBPL-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033756">
        <property type="entry name" value="YlxH/NBP35"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42961">
        <property type="entry name" value="PTHR42961"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10609">
        <property type="entry name" value="ParA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01215">
        <property type="entry name" value="MRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="101"/>
            <end position="108"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV54266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="353" mass="37389" checksum="E44F6CC4A193F18F" modified="2019-10-16" version="1">MTPDDIRSAIADFPDPETGRPIGSTDQIKSISCDSGIQVQVGLTSHSAALKEEVVEQLASRIVSRFAGQSPAIEIVDHDRPPARLGQIGLRVKSVIAVGSGKGGVGKSTVATSLAQCLQRFGSKVGLMDADVYGPSVPHLLGLSGRPEVDENKRIIPIKKGPMPVMSMGFLVEPDQAVIWRGPMLHSSVTQFLRDTDWGLLDYLIIDMPPGTGDVALTLSQILPLSGAVIVCTPQEVALLDAVKAIAMFGKVHIPILGMVENMSGFQCPDCNKHYDIFGKGGARDKAEELQTPFLGGVPINIPLRIAGDQGKLAECLDDDAIRAPMDQVARAVVRTLAAKNAAAPATPQLPTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMM3</accession>
    <name>A0A518IMM3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Outer membrane efflux protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_02890</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022187303" evidence="3">
        <location>
            <begin position="26"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="633"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="690"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="692"/>
            <end position="711"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV54336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="711" mass="79131" checksum="912D8461289B009C" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMS5</accession>
    <name>A0A518IMS5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alkaline phosphatase synthesis transcriptional regulatory protein PhoP</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">phoP_1</name>
        <name evidence="3" type="ORF">Mal33_03290</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041657">
        <property type="entry name" value="HTH_17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12728">
        <property type="entry name" value="HTH_17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="70"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="195" mass="21884" checksum="D703B1BB0C1786F0" modified="2019-10-16" version="1">MTTKTVFTTGEAAKICKVSQQTIIRCFDNGTLKGFRVPGSRFRRIPRDLLYSFMKDNGIPTDALESGKKKILVVDDDVDLVELIVEGLERDGRFDLRTANNGFDAGMQVKEFRPDLVILDVMLPDINGKEVCQRVRSDPAMDSVQIICISGMIEQDKVQSLRDAGANDFMQKPFAIEDLIARGCDLLEIERKAEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMS9</accession>
    <name>A0A518IMS9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Multidrug export protein EmrA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">emrA</name>
        <name evidence="3" type="ORF">Mal33_03510</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HlyD_D23" evidence="2">
        <location>
            <begin position="29"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="155"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="384" mass="42122" checksum="6ED2492D15BA9EF7" modified="2019-10-16" version="1">MIKRIAPLALLTAVLIGVLAYSQRATGPLKVSGFIEADEIRIGSRVGGRVAAVLVEEGATVAKGQELVRLEPFDLIESQREAAAQLAARQADLDRLAAGYQPEEIRQAKARVEQIAAQLEKLTNGPRPEEIAAAKGRQQAAEVELTLAQRTLDRASNLRDSNAVSQQEYEEADEKMKSARANLTVRNNELQLLEAGTRQEELDEAKAKLAEAEAAWELMKNGYRNELVRQAAAARDAAQATLDAIGQRLDELVIRSPVAGVVEALELQPGDLVSASGPVMSLMDNTNLWVRAYVPENHLDLQVGQRLPMSVDSFPDERFACEISFIARRAEFTPSNIQTPEERSKQVFRIKATLVEGLDRLRPGMSADLWLAEIEQPSAKNADE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMY9</accession>
    <name>A0A518IMY9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_04140</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021759013" evidence="1">
        <location>
            <begin position="27"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="421" mass="47547" checksum="A8063C53492ED26C" modified="2019-10-16" version="1" precursor="true">MWRTKTLTMSLAVAGLLMFQAGNCWSSEPSVDELPALRQLDDYVSSDANALDELTSQDFATTPLTRQECVAAERSLWTAYRNQILPERTKEHAANVVQVDGISMKYRKRRYGEPPAGGYSLVISMHGGGGTTARVNDQQWKNQIGLYTLEQGIYVAPRAPTDAWNMWHLPHIDPLFTRLIENMVLLENVNPDRVYLTGYSAGGDGVYQLAPRMADQFAAAAMMAGHPNETKPLGLRNLPFTLHMGERDAAYQRNEHAARWKRELATLRENDPEGYRHWVEIHADKGHWMDRQDASGVKWMMQFSRNLLPQRVAWLQDDVLHHRLYWLAVPDGTAKQGSKIIASRNGNTFTIEASDVDRFELLLRDDFVDLDSPIEVIYEGRTIFSGPAKRTIASLWSSIVDRGDPAATFSCRVPIALTDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INF3</accession>
    <name>A0A518INF3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">D-hydantoinase/dihydropyrimidinase</fullName>
            <ecNumber evidence="3">3.5.2.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">dht</name>
        <name evidence="3" type="ORF">Mal33_05710</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
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                <person name="Merkel B.J."/>
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                <person name="Mueller R.-W."/>
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                <person name="Op den Camp H."/>
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                <person name="Jetten M.S.M."/>
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                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
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                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
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    </reference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
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        </location>
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        <location>
            <begin position="84"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="457" mass="49385" checksum="85ADE0250BF602E2" modified="2019-10-16" version="1" precursor="true">MRSIHIILASTAVVLTILAPLARAQQAEEETPSYTLITDVNVFDGVADRLTPGRVLIEGNLIRAVGPNVETPDGAVVIDGGGRTLMPGLINCHVHLALPDAIANVESKLLFADVVLGSQLMARGYLMDGFTTVRDAGGNVFGIKKFIDRGLLPGPRIYPSGALISQLGGHFDLRNLTQHKTESHMERIGNIAICDGVPEVLVAARRNFRLQASQLKICVGGGAASDFDPVDTMQFTADEIRAAVTTANNWHTYVGAHIFTPQAMHIAADNGVMVFDHAFLIDEDAMKKVVEKGIFLVPQMNGLSPELLRNPILGPVNLAKIRTVHGQAGDFVALIKKFKPKIVFADDAFGTEDVVFKQRRYELGYRASLFGNFETLRQATSAAGELMALTGPRNPYSGKLGVIEEGALADMLIVDGNPLDDISVIGGTMEWFDAPPPKPIETIRVIMKDGKIFKNTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INF4</accession>
    <name>A0A518INF4_9BACT</name>
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            <fullName evidence="6">Putative diguanylate cyclase YdaM</fullName>
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        <name evidence="6" type="primary">ydaM_1</name>
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            <taxon>Planctomycetia</taxon>
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    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
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    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
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    </dbReference>
    <dbReference type="CDD" id="cd00077">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="GGDEF_dom"/>
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    </dbReference>
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        <property type="entry name" value="HD_domain"/>
    </dbReference>
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        <property type="entry name" value="HD_GYP_dom"/>
    </dbReference>
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        <property type="entry name" value="Nucleotide_cyclase"/>
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        <property type="entry name" value="PAS-assoc_C"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
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    <feature type="domain" description="HD-GYP" evidence="5">
        <location>
            <begin position="60"/>
            <end position="255"/>
        </location>
    </feature>
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        <location>
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            <end position="334"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="3">
        <location>
            <begin position="366"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="4">
        <location>
            <begin position="453"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS51832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV54624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="738" mass="81014" checksum="1E8845655508394A" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INP6</accession>
    <name>A0A518INP6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_06640</name>
    </gene>
    <organism evidence="2 3">
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        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetia</taxon>
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    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="QDV54707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="95" mass="10848" checksum="C25576B7FE6D4DDD" modified="2019-10-16" version="1">MASAIAKRSPQFVKILRQIGHAKSDCWQVEASDRKRPLRDTSINTESRFSSDVPQPPRVAAERTITTTLQSQQRKGCDRVSRTRNGGSKFFRDHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INQ6</accession>
    <name>A0A518INQ6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Serine/threonine-protein phosphatase 1</fullName>
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        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">pphA_1</name>
        <name evidence="2" type="ORF">Mal33_06490</name>
    </gene>
    <organism evidence="2 3">
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        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetia</taxon>
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            <taxon>Pirellulaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
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                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.3.16" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017018">
        <property type="term" value="F:myosin phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos" evidence="1">
        <location>
            <begin position="4"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="245" mass="27491" checksum="8CD084BF649F8B72" modified="2019-10-16" version="1">MSGRTIAFGDIHGCSRALRTLIENIAPTPEDTLVFLGDYVDRGSDSRGVVDQLIELQQRCNLVPLLGNHEIMFLGVVCGGMEDKIWLACGGNATLASYGGALHHIPTRHIDFLKTCRSYWENDRNICVHASYLPEQPMDRLGEQHLFWEHLPPVAPLPHHSGKRVLVGHTPQANLEVLDLGHLVCIDTYCFGGGWLTAFDLDTAEVWQANLHGHARRKFGLTVKRRIREAAQALRQRFSRKQATR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP56</accession>
    <name>A0A518IP56_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_08090</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022126633" evidence="1">
        <location>
            <begin position="25"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="403" mass="43283" checksum="F225B8675DCCFF07" modified="2019-10-16" version="1" precursor="true">MHTLKLLAAGLLLCTALPVGTVRAQSLDDAIKNMSDDIAVFLESREKTSVAIGEFDGPDGSTAGRAIQQKLKENLLANNLEIKKLGARMKIRGSFSLDSQSSFSIATIRSTLVDENGREMSGYRERVKLAEVTSLEDLSRIFGLTADLVAEQNGESDDADATSGSAKDQDSDAATLLTSVSKAVTKKVSNAIKTPGFSYHGNDKSKVKASDSSDFVVQLRRCPRDSSVFTPVDVLDEGGFAFAPLEDGDRYQVVVTNNSDHDIAAKVSIDGVNSFYFSGNPGFKANGSWVIAAGQSGVIKGWYLNAHELAEFLITSDEKDAKLPDPLDLGTVTVQFFHAWAHNTPVPKVELLAKNDRGQLQTTQGAVIGQQSGEVRRHFGKTLLASVSIRYSNPDDLPEGPGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP75</accession>
    <name>A0A518IP75_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Carbohydrate-selective porin, OprB family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_08640</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the OprB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015288">
        <property type="term" value="F:porin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008643">
        <property type="term" value="P:carbohydrate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007049">
        <property type="entry name" value="Carb-sel_porin_OprB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038673">
        <property type="entry name" value="OprB_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04966">
        <property type="entry name" value="OprB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022248861" evidence="2">
        <location>
            <begin position="27"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU363072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="422" mass="46225" checksum="4702736875B23184" modified="2019-10-16" version="1" precursor="true">MNHCLTLRITWKACLACLLVTSTARAGELAETYEAMQENGYSFTGNVTQFGFGVVGGGNDSLPDSLRYSGHGDYLLNVDASKFGLQDGLFFRLRAEHRFGEQLNPINTGSVMPPTIASHLPAETENLYITNLVVTQALSENFALFMGKFDTLEGDRNDFAHGRGISQFSNLALVTNPAAIVASPYSSLGAGFAILHDFEPLFVFTIMNPTDTTRTSGFDELFNDGVLLTAGLRVPTNFFGKRGHQSFTALYSTQFFSELVPDPRASLSAMSSNGAIKLSDEQEGTYAFLYNFDQYLYSDRQGRGFGLFGRVGVGDQSVNPLRLFLSAGIGGHNMLSRSRRNDSFGAGYYYLDATKDASLLDDIATATGQDFHDGQGLELYYNFNICSFMDLTFDYQLIDSVADSAVFEDPTSILGARLNIRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPA6</accession>
    <name>A0A518IPA6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_01700</name>
        <name evidence="2" type="ORF">Mal33_08850</name>
        <name evidence="3" type="ORF">Mal33_14940</name>
        <name evidence="4" type="ORF">Mal33_21020</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV56123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="147" mass="16429" checksum="B1AF19FA5FFFF2AD" modified="2019-10-16" version="1">MIKKYIVRLSDTEREELKAIVKKLKGSSQKVRRALILLKADTEGPGWSDAKIAEALACRIQTVENLRKRLVTEGFDTALHGKPRLSAPREKTLDGKQEAKVIALRLGKPPKGFASWSLRLLADHVVELGIVDSISYETVRQTLKKTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPC4</accession>
    <name>A0A518IPC4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 13">Tetraacyldisaccharide 4'-kinase</fullName>
            <ecNumber evidence="3 13">2.7.1.130</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12 13">Lipid A 4'-kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13 14" type="primary">lpxK</name>
        <name evidence="14" type="ORF">Mal33_09060</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 13">Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 13">Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 6/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the LpxK family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.130" evidence="3 13"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00359">
        <property type="reaction ID" value="UER00482"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009029">
        <property type="term" value="F:tetraacyldisaccharide 4'-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00409">
        <property type="entry name" value="LpxK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003758">
        <property type="entry name" value="LpxK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42724">
        <property type="entry name" value="PTHR42724"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02606">
        <property type="entry name" value="LpxK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00682">
        <property type="entry name" value="lpxK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 13 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 13" id="KW-0441">Lipid A biosynthesis</keyword>
    <keyword evidence="5 13" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="11 13" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 13 14" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00029757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="QDV54940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="350" mass="38646" checksum="AC1FD103CBAF7988" modified="2019-10-16" version="1">MDIRPIMSGQRRDPLARLLRMATRVAAIPYGVATTLRNRKYDRDASSIQHADVPVISVGNITTGGTGKSPMVAWIARVLRNEGLRVAIVSRGYGADASGVNDEALELEERLPDVPHVQNPDRVEGARVVVEELETEVILLDDGFQHRRLHRDLDIVLIDASCPFGYGYQLPRGMLRESLKGLKRADVVVLTRSDAASDADRRQIRESVQRFAATATWVESVHAPSALLTHAADPLPIETLRGQQVLVFSAIGNPDAFVKTVTDCGATLIDSKTFPDHHRFDREDIETLTAWVDQHPAAEAILCTHKDLVKLRTSRIGRLPLRAVGIKIAMTVGESELRQRLLQTARQATS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQ77</accession>
    <name>A0A518IQ77_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative efflux pump membrane fusion protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Mal33_12070</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039562">
        <property type="entry name" value="MFP_biotin_lipoyl_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13533">
        <property type="entry name" value="Biotin_lipoyl_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022091697" evidence="3">
        <location>
            <begin position="25"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="domain" description="Biotin_lipoyl_2" evidence="4">
        <location>
            <begin position="41"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="domain" description="HlyD_D23" evidence="5">
        <location>
            <begin position="187"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="359"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="95"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="209"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="360"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV55237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="378" mass="41614" checksum="153D0332349B8E0C" modified="2019-10-16" version="1" precursor="true">MVSFHRRYLCSVCLALLGASTLPAGDPLVLQRVFVKRIADVELAAPKAGLLAKVSVAEGASVSKDQPLAKLDDRNAQIDLQRAKIEYEVALQELSDRAEIELAQKRLEAAEQARKQFAIENDAAHRLAENRLAVQATEKSAAVAKNELDRAQHARNEFADSVSESEIEGLALAYQQAELESQQAEFQRQQDLLAANASDEALLSHRLAAEQASIELQQAKTDLQLARLNADLYQNSLDAAQLQLAQHQVQAPFDGVVVELYRQQGEWVKPGDPIVRVLRLDRLRVEGFLPTQLLRRDLVGSPAEIHVVGFAKQSLVFQGEVSFVSPEVDAVNNEVAIWAEFDNPELLAWPGMQGTLTIHLPDTAGKSPQSDTEETPQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQ90</accession>
    <name>A0A518IQ90_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_11930</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020022">
        <property type="entry name" value="N-acetyl_sugar_amidoTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03573">
        <property type="entry name" value="WbuX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="407" mass="47482" checksum="0263B3EA24926041" modified="2019-10-16" version="1">MTVSTTVPSEFVAANRTALRNTSRKQQTVEMNGYRICKQCVMDTTDTAITFDDEGICDHCHSVQEHVRPNWHTDQRGRDELARIVERIKHDGRKRDFDCIMGMSGGADSSYLLHVAVKDFGLRPLVFHVDGGWNSQLAVHNIEKMIDGLGLDLFTEVIDWEEMKDFQLSYFKSGLPNIDVPQDHAFIATLYNFADKHKIGYILNGGNYSTECVRNPLEFFYHGTDMAQIRDVQSRFGTRKLKNYPFSSILRHKFYLRYVRRIQVVKPLNYVPYIKADAMQELADLYDWTPYPQKHFESRFTRFYEGYWLPKKFGFDSRRVQFSSLILTDQMTREAALEELAKPAISDEDARNEFDYVAKKLGISTEELQGYFDQPNRSHRDYKNQEAMFQAGSKLLNWFGIERNVKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQ94</accession>
    <name>A0A518IQ94_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Tetratricopeptide repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_12120</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="354" mass="39009" checksum="D1232FF51F1F4666" modified="2019-10-16" version="1">MSEQKLRFPILCIGLITMLSGCRVGTGVHVWQPPLAANAAGKRIAVAPPVGPRALAGELSQSIAREQPKLPQRAELVSQYELSQSDAIQLVSFDGRAPSDLALLPVAKQAGLDLLLVGEVLNDPFGDSRQPLAHDDPDFQFKLGQFLQSRDDDQILAFSWRVIDVENGQTVWANPMSVSKAFVDRTYPDLAGQQTSLSQQLQAAAGRETWKLFAPFVDQYQTELAVPWISLGAKQTREGNRYALEGEWQQAEACWRQVLAEHPRQLAALHNLAVAAVARQDYAEARRLATEALSKRDSRLFQETLVWVEARQREYHQAFGLPDPVGGWTYQASRPAAVSLGSDSRGKSQLSATD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQD3</accession>
    <name>A0A518IQD3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protoporphyrinogen oxidase</fullName>
            <ecNumber evidence="2">1.3.3.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">hemY_2</name>
        <name evidence="2" type="ORF">Mal33_12760</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.3.3.4" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004729">
        <property type="term" value="F:oxygen-dependent protoporphyrinogen oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amino_oxidase" evidence="1">
        <location>
            <begin position="16"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="420" mass="45968" checksum="CD5FB9FCB9546477" modified="2019-10-16" version="1">MRDNRKKEVIIIGGGLAGLACGVQLAKRGVDFEILEATDRVGGRVRTDIVDGYRLDHGFQVFLTAYPAAQQLLDYDRLQLRPLEPGALVRCGDQFSSLLDPRRRPASILASALSPVGSLADKLRMARLSRDVCRGELDELWEHVAQPTRYRLPGLNFSDRFIEQFLQPLLGGIFLDPELQTSSRMMEFVLRMFAEGDAAVPAQGMQAIPQQLAERIPADRIQLESTVSEIDGTTVRMTDGSRRSANQIVIATEGPAAARLLKIDESIPWQQVSCLYFTADEAPLQTKQMILSGETSGPINNLCELSTVAPEYAPAGKTLISVSVLKSDVPAIELHEPVLKQLRSWFGEQVDTWSLLRTFHIPFALPEQSIDRMQTVIKPVQRAGMPIVCGDHRETASIQGALSSGIRAAEAALGGLGDAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQI6</accession>
    <name>A0A518IQI6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Piwi domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_13300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003165">
        <property type="entry name" value="Piwi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02171">
        <property type="entry name" value="Piwi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00950">
        <property type="entry name" value="Piwi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50822">
        <property type="entry name" value="PIWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Piwi" evidence="1">
        <location>
            <begin position="429"/>
            <end position="738"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="758" mass="85154" checksum="D78D010929FE0FF5" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQK7</accession>
    <name>A0A518IQK7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_13240</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016155">
        <property type="entry name" value="Mopterin_synth/thiamin_S_b"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54285">
        <property type="entry name" value="SSF54285"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="73" mass="8003" checksum="ADE8B00BD423E660" modified="2019-10-16" version="1">MKVLLISNDAGGYAHHVEAPENTTVGQMFERHVGAFHADSYLIRVNRQPASADQPLRDGDRVSFTPLKIEGAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQM8</accession>
    <name>A0A518IQM8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BON domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_13590</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007055">
        <property type="entry name" value="BON_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04972">
        <property type="entry name" value="BON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BON" evidence="1">
        <location>
            <begin position="25"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="77" mass="8411" checksum="2800F8FFDEB8049A" modified="2019-10-16" version="1">MTDGKNQNGSQETLHAKVERIVHKFGFDNVCVSSIKAGHVEMTGTVSNINDRALIVAIARTTPGVQQFSIEIKIEND</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQQ3</accession>
    <name>A0A518IQQ3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cysteine desulfurase</fullName>
            <ecNumber evidence="4">2.8.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">iscS_2</name>
        <name evidence="10" type="ORF">Mal33_13910</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[sulfur carrier]-H + L-cysteine = [sulfur carrier]-SH + L-alanine</text>
            <dbReference type="Rhea" id="RHEA:43892"/>
            <dbReference type="Rhea" id="RHEA-COMP:14737"/>
            <dbReference type="Rhea" id="RHEA-COMP:14739"/>
            <dbReference type="ChEBI" id="CHEBI:29917"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:64428"/>
            <dbReference type="EC" id="2.8.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 8">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.7" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031071">
        <property type="term" value="F:cysteine desulfurase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044571">
        <property type="term" value="P:[2Fe-2S] cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020578">
        <property type="entry name" value="Aminotrans_V_PyrdxlP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010240">
        <property type="entry name" value="Cys_deSase_IscS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016454">
        <property type="entry name" value="Cysteine_dSase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11601:SF34">
        <property type="entry name" value="PTHR11601:SF34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005572">
        <property type="entry name" value="NifS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00595">
        <property type="entry name" value="AA_TRANSFER_CLASS_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_5" evidence="9">
        <location>
            <begin position="6"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV55418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="388" mass="41474" checksum="DEDED6CC571FC32A" modified="2019-10-16" version="1">MSDEIIYLDNHATTRCDPRVVDAMLPLLLESYGNPHSTTHAAGHDAAEAVDAALHSLAQNLGATREELTVTSGATESTNLALLGHCLNPRNRKRHIVTAATEHPAVLDPIDALRREGFGVTTLEVDANGQIDATKFTESLTDDTAIVSLMLANNEIGSLHPLAELIEIAHARGIPVHTDATQAVGRIPIDVGRLEVDLLSCSAHKFYGPKGIGLLYVRRQGRLTRLKPRTFGGGQQRRLRPGTMNPAAIVGMATALQLCSDEMPTEPQRIAALRQRLMEGLCQRIAGLQLNGPPLDSEIRLPGNLNLMFPGVQGDALMLAAPRLAVSSGSACSSVDAAASHVLLGTGRSELQARSSLRFGIGRFNTAAQIDEAIAMLADAFDQMQQFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQR7</accession>
    <name>A0A518IQR7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">prkC_4</name>
        <name evidence="9" type="ORF">Mal33_14020</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011659">
        <property type="entry name" value="PD40"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07676">
        <property type="entry name" value="PD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="122"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="526"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="151"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV55429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="841" mass="92728" checksum="D9700E72E1E66D67" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQV3</accession>
    <name>A0A518IQV3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DDE_Tnp_1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_14450</name>
        <name evidence="3" type="ORF">Mal33_27680</name>
        <name evidence="4" type="ORF">Mal33_35500</name>
        <name evidence="5" type="ORF">Mal33_40080</name>
        <name evidence="6" type="ORF">Mal33_47270</name>
    </gene>
    <organism evidence="2 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 7">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002559">
        <property type="entry name" value="Transposase_11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01609">
        <property type="entry name" value="DDE_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_1" evidence="1">
        <location>
            <begin position="23"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV57540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV57992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV58703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="131" mass="14833" checksum="B10E44BB0FA0EDCB" modified="2019-10-16" version="1">MIETSNRLVGHVDWPGFAQAIRLTRTRILGGVRQTEISYAITSVDRERADARDLLKFVRGHWGIENRLHWVRDVAMGEDKCRARTGAIPQNLAALRNVTLTLVRSKGHNAITSTLRRLATKPMEIISILKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IR56</accession>
    <name>A0A518IR56_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tRNA pseudouridine synthase B</fullName>
            <ecNumber evidence="4">5.4.99.25</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">tRNA pseudouridine(55) synthase</fullName>
            <shortName evidence="4">Psi55 synthase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">tRNA pseudouridylate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">tRNA-uridine isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4 7" type="primary">truB</name>
        <name evidence="7" type="ORF">Mal33_15480</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>uridine(55) in tRNA = pseudouridine(55) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:42532"/>
            <dbReference type="Rhea" id="RHEA-COMP:10101"/>
            <dbReference type="Rhea" id="RHEA-COMP:10102"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="EC" id="5.4.99.25"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.25" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106029">
        <property type="term" value="F:tRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031119">
        <property type="term" value="P:tRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02573">
        <property type="entry name" value="PseudoU_synth_EcTruB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01080">
        <property type="entry name" value="TruB_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002501">
        <property type="entry name" value="PsdUridine_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014780">
        <property type="entry name" value="tRNA_psdUridine_synth_TruB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032819">
        <property type="entry name" value="TruB_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13767">
        <property type="entry name" value="PTHR13767"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16198">
        <property type="entry name" value="TruB_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01509">
        <property type="entry name" value="TruB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00431">
        <property type="entry name" value="TruB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="TruB_N" evidence="5">
        <location>
            <begin position="25"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="TruB_C_2" evidence="6">
        <location>
            <begin position="172"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF16198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV55571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="295" mass="32040" checksum="D91EE3754DF64400" modified="2019-10-16" version="1">MFGILNVNKPKGITSRAAVNRVYRAVKPNKAGHAGTLDPLAHGVLLVPIGSASRLVPYLHLLPKRYLASFELGMSSASDDSETEVTEHPELPAPSRIDLEQACAEMQGEILQRPPAYSAIKVEGKRAYKMARQGNLLDLPKRPVQIHRITLLHYEFPELVLEIDCGSGTYIRSIGRDLAQSLGTEAIMTALARTAIGPFKIQDATSIDDLTAEAARAALQPAARGVMHMPQTILDDDEVTEIINGRMIPFRALGPGFINDPQEIAALDESGRLRAILHSRDGGLGPKRVFPASMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IR60</accession>
    <name>A0A518IR60_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phospholipase/Carboxylesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_15100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003140">
        <property type="entry name" value="PLipase/COase/thioEstase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02230">
        <property type="entry name" value="Abhydrolase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Abhydrolase_2" evidence="1">
        <location>
            <begin position="14"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="245" mass="26589" checksum="69AE10BB3FBFCE91" modified="2019-10-16" version="1">MSALEQKIGPLQCVVIDGGEAPTILVVLCHGFGAPGDDLVPLGQYLLEMLGDDAEKFRFVFPTAPISLADQGMPGGRAWWPLNMQRLMELFQTNDFSELRRQEPPGIDEARQMLTETIEAVAGDFDKDAPLVIGGFSQGAMVSLDVALRGLKDPPAGLIQWSGTLICEAQWKAVAADRLKSVDALQSHGHSDFVLPMIGAQWLSELLDESSANFEFIQFDGPHTIPMESLQATAELLRRVAANAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRA4</accession>
    <name>A0A518IRA4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">4-carboxy-2-hydroxymuconate-6-semialdehyde dehydrogenase</fullName>
            <ecNumber evidence="2">1.1.1.312</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ligC_1</name>
        <name evidence="2" type="ORF">Mal33_16050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.1.312" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050606">
        <property type="term" value="F:4-carboxy-2-hydroxymuconate semialdehyde hemiacetal dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GFO_IDH_MocA" evidence="1">
        <location>
            <begin position="37"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="481" mass="52570" checksum="2129A0A6CA8F968B" modified="2019-10-16" version="1">MTQATRRQFVASGLAAGAVATLPGRRATAALANDEINVGFISCGGRSNELMGYFEKVPGVNIAGLCDPDQARLSRTSRRFPKAETWKDLRDLIASDSIDAVVVATCNHWHCLATIWAMEAGKDVYVEKPLSHSQWEGRQTVAAARKYDRICQVGTQQRSDPMQAEIQKYLHDDKALGAIQAVRVNRYGLRGSIGRRTEPLQIDKSVAYDLWLGPAQDEPIFRNNLQYDWHWDWNTGSGEMGNWGVHVLDDVRNNVFQDRVALPKQILGGGGRVVLGDAGQTPNVHFAYFDTGSIPVVIGLSNLPDKAGSKKSPAHPGPGSGYVVYCEGGRLEGQRGRAQAFDADGKKLASFKGSGGNVLHQANFIDAVRAHDRSLLNTEVAVGNDSTGWCNLANIAFRAGRPYSPQDAASVELPQWNTLIGEMGQHLKSHDLSLDNSAIQMSHLLTLDEKTEQFVGDDADAANAFLKRKYREGYEVPTIQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRD1</accession>
    <name>A0A518IRD1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">L-glutamine:scyllo-inosose aminotransferase</fullName>
            <ecNumber evidence="5">2.6.1.50</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">stsC</name>
        <name evidence="5" type="ORF">Mal33_16350</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the DegT/DnrJ/EryC1 family.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.50" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047310">
        <property type="term" value="F:glutamine-scyllo-inositol transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080100">
        <property type="term" value="F:L-glutamine:2-oxoglutarate aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000653">
        <property type="entry name" value="DegT/StrS_aminotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30244">
        <property type="entry name" value="PTHR30244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01041">
        <property type="entry name" value="DegT_DnrJ_EryC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000390">
        <property type="entry name" value="PLP_StrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="294"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="191"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="2">
        <location>
            <position position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR000390-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000390-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV55656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="371" mass="39597" checksum="E28C451232106774" modified="2019-10-16" version="1">MPHVATADPLPLPTWPPTSPAIVDSIRQAAESGDWGKYAAQASRSLADRLASRFDVEHVRLCASGTAAVELALRAVQVRPDSEVILAGYDYPGNIRAIEAVGAKPVIVDTEPGRWVIDADLVEQAIGESTTAILASHLYGDLFDAKRLRELADQRGIALVEDACQVHGASLAGKPAGSWGHVGVLSFGASKLMTSGCGGALLSSDDRIAQRATLAAERPSGIAPLSGLQAAALLPQLATLDEWNAQRRTAVARLKQLLAGSRIWQFAEAMPYESETTYFKAAWFLSAGIPRDSVIAAGLAAGIPLGTGFNGFLRRARRRYRTVGDLSQSEICIDRSVVMDHRVLLADLDVIDTIAERLLAIERDLESKADA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRQ4</accession>
    <name>A0A518IRQ4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">C4-dicarboxylic acid transporter DauA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">dauA_3</name>
        <name evidence="8" type="ORF">Mal33_17480</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the beta-class carbonic anhydrase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004089">
        <property type="term" value="F:carbonate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008271">
        <property type="term" value="F:secondary active sulfate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001765">
        <property type="entry name" value="Carbonic_anhydrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036874">
        <property type="entry name" value="Carbonic_anhydrase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011547">
        <property type="entry name" value="SLC26A/SulP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001902">
        <property type="entry name" value="SLC26A/SulP_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11814">
        <property type="entry name" value="PTHR11814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00484">
        <property type="entry name" value="Pro_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00916">
        <property type="entry name" value="Sulfate_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00947">
        <property type="entry name" value="Pro_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53056">
        <property type="entry name" value="SSF53056"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="49"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="88"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="121"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="180"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="211"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="268"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="307"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="346"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="400"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfate_transp" evidence="7">
        <location>
            <begin position="22"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV55769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="759" mass="80523" checksum="33EC79A0797507B1" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRU6</accession>
    <name>A0A518IRU6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_17520</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007825">
        <property type="entry name" value="Major_OMP_Legionella"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05150">
        <property type="entry name" value="Legionella_OMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="318" mass="34683" checksum="11A893284F1D3AAD" modified="2019-10-16" version="1">MRPRRVDENRQEAPGGCVVWRMRDIAKESKLKKLLQHVGVALGLVCGATASAEEAVVTSLYEEAMIADQEPVQLVGYKSVGPIGSQLQKFRPRGVFSVGAELPLLSTYANHGLNPSSSTWSDGYDTEAALRVTAAYQTTGIMGFRFRFFDFEATNNSTPQSSFGVQTYDLEATTDLKLGEWKIQGFGGLRWGSIDFSKSRWGGFENNEFDGFGFTLGADVRRHVAHGFSLVAGFRQSMLYGETQSSTGNRLDNVVVPVTELRLGAEYAHVFAGGNKLIAGVGYEHQQFSSLSSLAGSIDPEDVDLALAGPVFSLTWQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IS43</accession>
    <name>A0A518IS43_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_18520</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="5"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="161"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="203"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="228"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="271"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="294"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="328" mass="35367" checksum="0651095C0572AA77" modified="2019-10-16" version="1">MRYGLTTGIVTAAVCVLLAWFALPVDKHYLAPLASLVALTLPLQHIRLAVQGVDHGRGYFYRLSSLRAAAAAFFPLLLLGMWLAGWSELRDVTWAFVGSCVAGLLLCQVGMRGSWFGPPQQSVLESLSENRGLAISQIAAELLDRADLFLIMFLGTLTDQGFYTSAIPIASTMIIVPNALALFSFRHGADPNTPLTAAGVTRFIALMFAGQIATGCLLAIVIPYAVPILYTQAFTGTVMFAWYLLPSGGLRGMLMTADGYLRGRGMPTPGIIGRIVALMILIGLTFALQPRMGIWSIPVALAAGQFVCLVIVFFAMYRQTQANSQNKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IS92</accession>
    <name>A0A518IS92_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Isochorismatase family protein YecD</fullName>
            <ecNumber evidence="2">3.-.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">yecD</name>
        <name evidence="2" type="ORF">Mal33_19380</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.-.-.-" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000868">
        <property type="entry name" value="Isochorismatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00857">
        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="SSF52499"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isochorismatase" evidence="1">
        <location>
            <begin position="73"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="246" mass="27370" checksum="D231A8E59E493121" modified="2019-10-16" version="1">MTDNEHVDPLKEVYHESFVENPAHKEFLIEGRTALLCIDLQYLDAAPGHGVFKDAMNSGVPQEAQEYYFDRLQQTVLPNVRGLQDAFRSHGLEVIHTRIQALTRDGRDRSKGHRRLGLLAAPGSREADFLEIVGPDESRDEIVINKTASGVFSSTNLHYVLKNMGIESLFVVGVYTNECVETTVRDACDLGYLVTVVEDCCATVTPELHDASLATLRDRYARILKYAEVARMIAPLVPADTVAPNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISH2</accession>
    <name>A0A518ISH2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Inner membrane protein YphA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">yphA</name>
        <name evidence="6" type="ORF">Mal33_20100</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032808">
        <property type="entry name" value="DoxX"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07681">
        <property type="entry name" value="DoxX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="51"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="75"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="113"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV56031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="147" mass="15963" checksum="FD98B11D00AAF357" modified="2019-10-16" version="1">MNSNPLQGVAAVLGRIMIATIFLMSAIGNKIPKFNDVVAYMGSEGVPMPKVMLAGAIVFLIAGSLSIILGFKARIGATLLLVFLVLATYFFHDFWTMEGEAQQMQMIQFMKNLSMMGTMIFLIAQGSGPMSLDNRATHVRKEESPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISM8</accession>
    <name>A0A518ISM8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_20320</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="307"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="332" mass="36495" checksum="FD9E81746AC97767" modified="2019-10-16" version="1">MPMPVRRFTTVLLYVVCCLMLLAGPVQGLDFGDKRAEREAAIAALPLDRLTQTARKRVEQIISHPTMFRRLPTQGMDCDRDMFLFLVRHPEVLVGIWDVMDITQVQMKRTGPYNLVASDGQGTTCEIELIYGDSQTHLYIARGKYEGSMVAKPLTGSGVFVLHSSYARSSRERETIGGRMDVFLELDSLGADLVVRTLGPLIGKSADHNFIETAKFIAQISQASEVNPEGVKKLGLQLPQVSEPVRSGFIDTAIAVGRRNGNTIADEPPIAMNDSPLGRTLDGKPAVETKVPTPVPVRVASSRPAAIDADQDAVDRYDNPVQPRKLGMNLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISP3</accession>
    <name>A0A518ISP3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Lipid A export ATP-binding/permease protein MsbA</fullName>
            <ecNumber evidence="10">3.6.3.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">msbA</name>
        <name evidence="10" type="ORF">Mal33_20690</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.6.3.-" evidence="10"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="16"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="129"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="222"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="325"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="355"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="124"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="424"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="457"/>
            <end position="464"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV56090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="666" mass="74171" checksum="0FA0EFB4B6A03BE2" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISZ3</accession>
    <name>A0A518ISZ3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein adenylyltransferase SelO</fullName>
            <ecNumber evidence="9">2.7.7.n1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">selO</name>
        <name evidence="10" type="ORF">Mal33_21890</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + L-seryl-[protein] = 3-O-(5'-adenylyl)-L-seryl-[protein] + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:58120"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:15073"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:142516"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + L-threonyl-[protein] = 3-O-(5'-adenylyl)-L-threonyl-[protein] + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:54292"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:13847"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:138113"/>
            <dbReference type="EC" id="2.7.7.n1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + L-tyrosyl-[protein] = diphosphate + O-(5'-adenylyl)-L-tyrosyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:54288"/>
            <dbReference type="Rhea" id="RHEA-COMP:10136"/>
            <dbReference type="Rhea" id="RHEA-COMP:13846"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:83624"/>
            <dbReference type="EC" id="2.7.7.n1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the SELO family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.n1" evidence="9"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00692">
        <property type="entry name" value="SelO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003846">
        <property type="entry name" value="SelO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32057">
        <property type="entry name" value="PTHR32057"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02696">
        <property type="entry name" value="SelO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 9" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Proton acceptor" evidence="9">
        <location>
            <position position="268"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="100"/>
            <end position="103"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="134"/>
            <end position="135"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="269"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="278"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV56208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="523" mass="59105" checksum="9629617FE0670307" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IT79</accession>
    <name>A0A518IT79_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_22620</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="346"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="346"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="684" mass="78282" checksum="4103F6FD1E7B1C5F" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITA9</accession>
    <name>A0A518ITA9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ECF RNA polymerase sigma factor SigW</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">sigW_3</name>
        <name evidence="4" type="ORF">Mal33_22850</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="2">
        <location>
            <begin position="22"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="3">
        <location>
            <begin position="131"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV56303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="196" mass="22660" checksum="F5F9B437BB35DFD4" modified="2019-10-16" version="1">MFESDAAAEDDLPPPRIDPENWVDRYGDAMYRYAYSKLGDHGVAEETVQESFVAALRARDSFRGDSSVSTWLFAILRRKIVDHYRRRNVREVTLAGDGEQAAPKSRSLSSRHRWGDDPAAMFEEQEFWETFDRCVDKLPDKLAEVHLLREGSQHRPKEICKILGISATNLSMRLHRSRLALRDCLQKNWFQDDGFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITB6</accession>
    <name>A0A518ITB6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="12">RNA polymerase sigma-54 factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">rpoN</name>
        <name evidence="12" type="ORF">Mal33_22950</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-54 factor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001216">
        <property type="term" value="F:DNA-binding transcription activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000394">
        <property type="entry name" value="RNA_pol_sigma_54"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007046">
        <property type="entry name" value="RNA_pol_sigma_54_core-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007634">
        <property type="entry name" value="RNA_pol_sigma_54_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038709">
        <property type="entry name" value="RpoN_core-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32248">
        <property type="entry name" value="PTHR32248"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00309">
        <property type="entry name" value="Sigma54_AID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04963">
        <property type="entry name" value="Sigma54_CBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04552">
        <property type="entry name" value="Sigma54_DBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000774">
        <property type="entry name" value="RpoN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00045">
        <property type="entry name" value="SIGMA54FCT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02395">
        <property type="entry name" value="rpoN_sigma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00718">
        <property type="entry name" value="SIGMA54_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Sigma54_CBD" evidence="11">
        <location>
            <begin position="125"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma54_DBD" evidence="10">
        <location>
            <begin position="330"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="44"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="50"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF04963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QDV56313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="494" mass="56700" checksum="7BBBE1F4309694EC" modified="2019-10-16" version="1">MGFEQRQQQVQKLAPRMIQSMEILQLPLLALQERVEQEMNENPLLEIQDDDPQMPDDPEESYENPDAPSESERELVVDNDHDNQDDFERLLNMKNELPNTFDEPFRKSSNQMQEDGDRRHDLMANAEAHPESLNDFLLHQLAELDIDTDVELMAERIISTLDARDGGYLRTPLSDLLPSNHSPEDLELAKRALAVVQSLEPTGIAARDLSECLLLQLAPDVPYYEEMKTLITGHLEDIAGNRLPAIQRKTGYSLDKIQKVKDELHSLNPKPGAAFMETYVPTVTPDVIVEQDEDGQYKVRLDDDRVPTLFISEYYRQRLQDPSATTEEREYIKQKINGAQWLIDSIEQRRSTLTKVSQAIVDHQKAFLDLGPEAIEPLKMQQIADRVGVHVTTVSRAVDDKWIQTARGILPLKRFFVGGTQTEDGDDVAWDTIRIKLQEVIDNEDKSKPLSDEDIVKELKKHGMTVARRTVTKYRKKMGIPSSRQRRDWMLENK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITB7</accession>
    <name>A0A518ITB7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Adenosylhomocysteinase</fullName>
            <ecNumber evidence="4">3.3.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">S-adenosyl-L-homocysteine hydrolase</fullName>
            <shortName evidence="4">AdoHcyase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ahcY</name>
        <name evidence="9" type="ORF">Mal33_23180</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4 6">
            <text>H2O + S-adenosyl-L-homocysteine = adenosine + L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:21708"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16335"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:58199"/>
            <dbReference type="EC" id="3.3.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4 6">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
        <text evidence="4 6">Binds 1 NAD(+) per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 6">Amino-acid biosynthesis; L-homocysteine biosynthesis; L-homocysteine from S-adenosyl-L-homocysteine: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 7">Belongs to the adenosylhomocysteinase family.</text>
    </comment>
    <dbReference type="EC" id="3.3.1.1" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00314">
        <property type="reaction ID" value="UER00076"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004013">
        <property type="term" value="F:adenosylhomocysteinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00401">
        <property type="entry name" value="SAHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1480">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00563">
        <property type="entry name" value="AdoHcyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042172">
        <property type="entry name" value="Adenosylhomocyst_ase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000043">
        <property type="entry name" value="Adenosylhomocysteinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015878">
        <property type="entry name" value="Ado_hCys_hydrolase_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020082">
        <property type="entry name" value="S-Ado-L-homoCys_hydrolase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23420">
        <property type="entry name" value="PTHR23420"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05221">
        <property type="entry name" value="AdoHcyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00670">
        <property type="entry name" value="AdoHcyase_NAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001109">
        <property type="entry name" value="Ad_hcy_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00996">
        <property type="entry name" value="AdoHcyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00997">
        <property type="entry name" value="AdoHcyase_NAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00936">
        <property type="entry name" value="ahcY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00738">
        <property type="entry name" value="ADOHCYASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00739">
        <property type="entry name" value="ADOHCYASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 4 6" id="KW-0520">NAD</keyword>
    <keyword evidence="2 4 6" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AdoHcyase_NAD" evidence="8">
        <location>
            <begin position="196"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4 5">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 5">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 5">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="162"/>
            <end position="164"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 5">
        <location>
            <position position="191"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 5">
        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="225"/>
            <end position="230"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="248"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="283"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="304"/>
            <end position="306"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="359"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001109-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV56336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="445" mass="48610" checksum="4185A0AF530F522B" modified="2019-10-16" version="1">MSQAEMTREAYKVKDISLAEFGRKEIMLAENEMPGLMALREKYGKSKPLAGARIAGCLHMTIQTAVLIETLVELGADVTWSSCNIFSTQDHAAAAIAAAGIPVYAWKGMTEEEFNWCIEQTLTFPSGEKLNMILDDGGDLTAMVHERFPELLDDIRGISEETTAGIHRLQVLEKKGLLKVPAINVNDSATKSKFDNLYGCRESLADGVKRATDIMLAGKVAVVAGYGDVGKGCAHSLQRYGCRVIVTEIDPINALQAAMEGFEVTTMDNAAKEGNLFVTTTGNKDIILGEHMAAMPNDAIVCNIGHFDTEIDIAWLEREVAAGKVTKLNIKPADIGAVDRYTFADGHSVIVLAQGRLVNLGCATGHPSFVMSTSFTNQCLAQMELWSNTDQYEVKTVLLPKRLDEEVARLHLDKLGVKLTTLTADQAEYMGVPVEGPYKPDHYRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITP1</accession>
    <name>A0A518ITP1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">tRNA-dihydrouridine synthase</fullName>
            <ecNumber evidence="5">1.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">dus_1</name>
        <name evidence="8" type="ORF">Mal33_24450</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 5">Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a 5,6-dihydrouridine in tRNA + NAD(+) = a uridine in tRNA + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:54452"/>
            <dbReference type="Rhea" id="RHEA-COMP:13339"/>
            <dbReference type="Rhea" id="RHEA-COMP:13887"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 5,6-dihydrouridine in tRNA + NADP(+) = a uridine in tRNA + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:23624"/>
            <dbReference type="Rhea" id="RHEA-COMP:13339"/>
            <dbReference type="Rhea" id="RHEA-COMP:13887"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the dus family.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.-" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017150">
        <property type="term" value="F:tRNA dihydrouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02801">
        <property type="entry name" value="DUS_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035587">
        <property type="entry name" value="DUS-like_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001269">
        <property type="entry name" value="DUS_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024036">
        <property type="entry name" value="tRNA-dHydroUridine_Synthase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01207">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006621">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0288">FMN</keyword>
    <keyword evidence="5 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Dus" evidence="7">
        <location>
            <begin position="30"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00002790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR006621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR006621-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV56455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="359" mass="39900" checksum="E38711108182C2D1" modified="2019-10-16" version="1">MNDSALLTETPHLPPLSLGPVEIGFPVVQAALSGYSDWPMRMIARRAGASYTLCEVMLDQFLLAVKQRNKTRHFLHISDEEHPVGGQLMGAEPEQFAAGALRLVEAGFDVIDINFGCPVKKVLGRCRGGFHLSQPEVALEIVRRTRDIVPDPIPVTVKMRRGIDDSEQSRDNFFTIIDGAFDAGVAAVTVHGRTVEQRYKGPSRWSFLKEVKQHVGDRTILGSGDLFTADDCLRMMRETGIDGVTVARGAIGNPWIFAQARALAQGLELPAPPTVLEQRAVMESHYDLMQQMYGDRAPMLMRKFAIKYSASHPEFDALKVAFSRLKSAEEFVAVLDQYYQQDRPGQYPPSTVHATQQEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITU7</accession>
    <name>A0A518ITU7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phage capsid family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_24990</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024455">
        <property type="entry name" value="Phage_capsid"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05065">
        <property type="entry name" value="Phage_capsid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01554">
        <property type="entry name" value="major_cap_HK97"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="463" mass="50732" checksum="3387BE36744900E5" modified="2019-10-16" version="1">MTPEELKALQEQRGKLAAEIKRQATAYNERKEKRANAPEQELWPDETRTHWDKVNADYDAVETQLREATEATEIERRVGSLDDGSGNRGQFDPTADLGRGDRRRNDPQTNIAEQRALALQGWARTAAGMDLSKEHRDAMKQVGYRGKNIEINLSGTEQLRARQEIFATHHPTHTKRALTTQTGNSGGFTVPTGFVNQLEIAMLQFNGVEQVASIFSTTEGNPMPFPTANDTGNEGEIVGENADVSTEANPTFGQVLFGADKYSSKLVKVPFELLTDSAFNFALLLGAMLGERIGRKANGEFTVGTNGIVTQATVGKTAALETAITPEELIDLQESVDSAYRSGNSVCFMMHSLIISAIRKLKVDGNFIWQSGLQAGVPDTLLGDRLVRNSKMASTMEADAKVALYGDCSKYGIRRVGSVRLMRASELYLENDQVGFIAFLRQCGRLIDAGTHPVKVLKMAAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITX7</accession>
    <name>A0A518ITX7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">Ribokinase</fullName>
            <shortName evidence="10">RK</shortName>
            <ecNumber evidence="3 10">2.7.1.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10 14" type="primary">rbsK</name>
        <name evidence="14" type="ORF">Mal33_25330</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>ATP + D-ribose = ADP + D-ribose 5-phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13697"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:47013"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.15"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="10">Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.</text>
    </comment>
    <comment type="activity regulation">
        <text evidence="10">Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.</text>
    </comment>
    <comment type="pathway">
        <text evidence="10">Carbohydrate metabolism; D-ribose degradation; D-ribose 5-phosphate from beta-D-ribopyranose: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the carbohydrate kinase pfkB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.15" evidence="3 10"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00916">
        <property type="reaction ID" value="UER00889"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004747">
        <property type="term" value="F:ribokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019303">
        <property type="term" value="P:D-ribose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01174">
        <property type="entry name" value="ribokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01987">
        <property type="entry name" value="Ribokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002173">
        <property type="entry name" value="Carboh/pur_kinase_PfkB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011877">
        <property type="entry name" value="D_ribokin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002139">
        <property type="entry name" value="Ribo/fructo_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017583">
        <property type="entry name" value="Tagatose/fructose_Pkinase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000535">
        <property type="entry name" value="1PFK/6PFK/LacC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00990">
        <property type="entry name" value="RIBOKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02152">
        <property type="entry name" value="D_ribokin_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00584">
        <property type="entry name" value="PFKB_KINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 10 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="8 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 10" id="KW-0630">Potassium</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PfkB" evidence="13">
        <location>
            <begin position="12"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="20"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="48"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="261"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="149"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="193"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="229"/>
            <end position="234"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="255"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="257"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="260"/>
            <end position="261"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="261"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="291"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="294"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="296"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005380"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR000535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="QDV56541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="316" mass="32507" checksum="9C746FA5DED770D3" modified="2019-10-16" version="1" precursor="true">MSTPESTNRGAQIVVLGSINMDLMIRCNQLPRPGQTIIADSSAEVPGGKGANQAVAAARAGGNVSMIGRVGDDAFSSRLVENLQREQVATDGVLPTTETPSGLAIVAVESSGENSIVAVPGANARLSPADVTTFADRIRTADVLMLQLEVPIETVQAAIEVARQAGVTIVLDPAPMPATLDDSLLRVDLICPNESETEAIVGHPVSSDEEIDRAIARLHARGARQVILTLGSRGAVASDGTTIRRIDPTPIDPVDTTAAGDAFAGALAVRLAEGANLFEAAGFAAVAGALAATRPGAQPGMPTRTEIDQILQSQKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITZ2</accession>
    <name>A0A518ITZ2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosomal RNA small subunit methyltransferase E</fullName>
            <ecNumber evidence="6">2.1.1.193</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rsmE</name>
        <name evidence="7" type="ORF">Mal33_25510</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6">Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>S-adenosyl-L-methionine + uridine(1498) in 16S rRNA = H(+) + N(3)-methyluridine(1498) in 16S rRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42920"/>
            <dbReference type="Rhea" id="RHEA-COMP:10283"/>
            <dbReference type="Rhea" id="RHEA-COMP:10284"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74502"/>
            <dbReference type="EC" id="2.1.1.193"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the RNA methyltransferase RsmE family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.193" evidence="6"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006700">
        <property type="entry name" value="rRNA_ssu_MeTrfase-E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30027">
        <property type="entry name" value="PTHR30027"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04452">
        <property type="entry name" value="Methyltrans_RNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015601">
        <property type="entry name" value="MTase_slr0722"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="SSF88697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00046">
        <property type="entry name" value="TIGR00046"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6 7" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR015601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV56559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="240" mass="25808" checksum="D044F10598009E59" modified="2019-10-16" version="1">MSQRYLVPDLIGHSSVALTDDEAHHAAGVMRVKPGATLTLFDGQNNEAQATVESVSRKRVECRIDQIGEVDRESPRMLLIAVALPKGDRARSVIEKAVELGAHGFVPIVCRRSVARPSDGQRKRLERYVIDASKQCGRNRLMQIAPAIPWSDFVAAETSELFDGTAIDPPAEVQRIVADPTGVSADPSGQHPVLFAVGPEGGFDPEEIEAAMEAGWSTISLGPRILRVETAVGALLSIAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITZ8</accession>
    <name>A0A518ITZ8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_25560</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="138" mass="15139" checksum="1CE130367AF26A47" modified="2019-10-16" version="1">MMDCAAAIPRYVLRKGLHPLGPSVKQIPGQPAVSAIFAFSSKPQYDAFLRADTSSLTPYPLVKGFLQNQNDLEELHLVVIDANSPNQSVIYAATVQAVLESLEQARASILPTHHLIRDEKSDAYRVQTPEMVCSHSVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IU75</accession>
    <name>A0A518IU75_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Phosphate import ATP-binding protein PstB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">pstB_1</name>
        <name evidence="6" type="ORF">Mal33_26370</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015415">
        <property type="term" value="F:ATPase-coupled phosphate ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:inorganic phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03260">
        <property type="entry name" value="ABC_PstB_phosphate_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015850">
        <property type="entry name" value="ABC_transpr_PstB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005670">
        <property type="entry name" value="Phosp_transpt1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43423">
        <property type="entry name" value="PTHR43423"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43423:SF3">
        <property type="entry name" value="PTHR43423:SF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00972">
        <property type="entry name" value="3a0107s01c2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="17"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="49"/>
            <end position="56"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV56644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="263" mass="29244" checksum="F87421FDDE447276" modified="2019-10-16" version="1">MANDANQSPGESAEAAISTHNFNAWYGDFQALHDLSLQIPRNRVTAFIGPSGCGKSTFLRWINRMNDTVAIARASGSLQMGDLDLLSDRTDVVDLRRRIGIVFQKPNPFPKTIFENVAFGPRLHMRISRSELEELVEWALRKAAVWNEVKDRLNGPAFGLSGGQQQRLCIARAIATGPEVLLMDEPCSALDPASTLAIEDLIYELREQYTIVIVTHNMQQASRCSDQTAFFYEGKLIELGSTSQVFTKPSNKQTEDYVSGKFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUF8</accession>
    <name>A0A518IUF8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Flotillin-like protein FloA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">floA</name>
        <name evidence="7" type="ORF">Mal33_26980</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts FMMs are highly dynamic and increase in number as cells age. Flotillins are thought to be important factors in membrane fluidity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homooligomerizes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Membrane raft</location>
            <topology evidence="5">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the flotillin-like FloA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045121">
        <property type="term" value="C:membrane raft"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01562">
        <property type="entry name" value="FloA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022853">
        <property type="entry name" value="FloA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12127">
        <property type="entry name" value="YdfA_immunity"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="15"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="271"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV56700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="330" mass="35581" checksum="534646417E0F61D7" modified="2019-10-16" version="1">MFSQFDLLGITTEAALFLGFVIFCVFFGLIATFFGLRYGKLWFQAWMSGADVSITSLLRMHFCKVHASTIVTAKVMAAQAGLDISPRSGISTRRLEAHYLAGGNVMNIINAIIAAHRANIPLVFDQAAAIDLAGRDVLDAVRTSVYPKVIDCPDPKRSGKTTLSAISMDGVELRVRARVTVRTNLEQLIGGATEETIIARVGESIISSLGSSKSHSMVLENPDLITRAVLSRGLDAHTAFEIVSIDIADIDVGENIGARLQADQAEADTRVARANAERRRAEAVAVEQENKAKVAENRARLVLSEAEVPQAMAEAFRGGRITVGESNGRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUH2</accession>
    <name>A0A518IUH2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">mRNA interferase MazF</fullName>
            <ecNumber evidence="1">3.1.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">mazF</name>
        <name evidence="1" type="ORF">Mal33_27250</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.-.-" evidence="1"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003477">
        <property type="entry name" value="PemK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011067">
        <property type="entry name" value="Plasmid_toxin/cell-grow_inhib"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33988">
        <property type="entry name" value="PTHR33988"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02452">
        <property type="entry name" value="PemK_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="114" mass="12275" checksum="410463D7366B11E5" modified="2019-10-16" version="1">MNVGDIHWVDFPRANGREQQGRRPAIIMQEDRYAGGLPTALVVPLSTAIRALRFAGTTTIAASSESGLGKASVALVFQLRAIDRGRIREKMGHIGDAGCEAVFNELSKLLGRSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUK1</accession>
    <name>A0A518IUK1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_27620</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="139"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="566" mass="54272" checksum="A3190F913EEB4559" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUS6</accession>
    <name>A0A518IUS6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Biopolymer transport protein ExbD/TolR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Mal33_28200</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the ExbD/TolR family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003400">
        <property type="entry name" value="ExbD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30558">
        <property type="entry name" value="PTHR30558"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02472">
        <property type="entry name" value="ExbD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="29"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV56820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="157" mass="17330" checksum="3C6ED3C96B24439A" modified="2019-10-16" version="1">MSTAAPIDEIDDDPPIMTSTRSDDDEMDITPMIDITFLLLIFFVVCSKMDPSQTTNLPLADNGLAVSAKDSAVVKMKRGTGETAELQSNDGVTFSNDPEAQLEAITRYITRERESGKAKIMLMCEKDVRSGEVTRVQKMLGDAFPEVEQTYIAVKEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUW4</accession>
    <name>A0A518IUW4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_28790</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="97" mass="10723" checksum="6BC7DECF06B1C76C" modified="2019-10-16" version="1">MPNSSRRPGDPMPVIGGGTMAADLIDDLNDDFVASNDAFPDDPLAQRAYDLLTLNADQLSLRFRNSDLAKMDDDTKRLLIQDLCDSLEIKPLRSDTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUX2</accession>
    <name>A0A518IUX2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_28800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="198" mass="22311" checksum="F27F9F611EE51E74" modified="2019-10-16" version="1">MNLPTRMRLEACASEETEIAEIQFLGREDAKRGIDAQWWSDDLETKTPLADEPDSHWNWCEIISYYQNKPKFIARCVQTPDGAIQGAMLVRRKVKSVLDPGQNAVFIDRIATAPWNRDKLAKNPLYRGVGTGFVLYSIVLSYTQGFGGRVNLQAVASEEFHAKQGFEPTTIQQDGEIVWEIPADVAQKKLIERGIIDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IV18</accession>
    <name>A0A518IV18_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">N-acetylmannosaminyltransferase</fullName>
            <ecNumber evidence="1">2.4.1.187</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">tagA_2</name>
        <name evidence="1" type="ORF">Mal33_29340</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.4.1.187" evidence="1"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="F:N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06533">
        <property type="entry name" value="Glyco_transf_WecG_TagA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004629">
        <property type="entry name" value="WecG_TagA_CpsF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34136">
        <property type="entry name" value="PTHR34136"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03808">
        <property type="entry name" value="Glyco_tran_WecG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00696">
        <property type="entry name" value="wecG_tagA_cpsF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="306" mass="33900" checksum="CC13AF446C5D5CE2" modified="2019-10-16" version="1">MSNAFQTNAAAQVFLDRKPVHADRALSKLEAQIVQLEARVEEALAEPDSNGDRSPAKPEAVEIWGVPFSRLTLGQTLQHVDRLVAAGQPGYFITANLNYNMLTSQHPELRQVNDDAAFIVCDGMPMVWRSRWTDSPLPERVAGSELIYALTKWSAHKGHRIYFLGGAPGVAQAAADKLSARYPGLTVAGVHSPPFRSLDDQEHADLIDQIRSSKPDIVYVAMGQPKGELWIAENYRAIGAPVCVQIGASFDFVAGGVARAPRWIQRAGLEWCYRMAQEPRRLAGRYWQNGKFLLRALWQETPLGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVC4</accession>
    <name>A0A518IVC4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phytanoyl-CoA dioxygenase (PhyH)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_30420</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008775">
        <property type="entry name" value="Phytyl_CoA_dOase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05721">
        <property type="entry name" value="PhyH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="263" mass="29825" checksum="B1A144C502A65C1F" modified="2019-10-16" version="1">MTSRLQITADDKATFDREGFLMVSQLLSPPEVQLLEQIARRDREIESAATARSDAAGGQTVLAVRDHLSDDMFSAIARCQRVAGSMQSLMGEEIYHYHHKLMLKEPRVGGAWEWHQDYGYWYNYGCLFPRMASCYIAIDRAGRDNGCLQVIPQSQQLGRLEHGKVGGQTGADEARVDQILKRLPLLHVEMQPGDALFFHGNLLHRSDQNRSEHSRWSLICCYNARSNNPYEVIRHNGYQPLEMIGDDDVMTAGTNQWNALTQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVM3</accession>
    <name>A0A518IVM3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Diacylglycerol kinase</fullName>
            <ecNumber evidence="2">2.7.1.107</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">dagK_2</name>
        <name evidence="2" type="ORF">Mal33_31340</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.1.107" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004143">
        <property type="term" value="F:diacylglycerol kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003951">
        <property type="term" value="F:NAD+ kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017438">
        <property type="entry name" value="ATP-NAD_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005218">
        <property type="entry name" value="Diacylglycerol/lipid_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001206">
        <property type="entry name" value="Diacylglycerol_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045540">
        <property type="entry name" value="YegS/DAGK_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00781">
        <property type="entry name" value="DAGK_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19279">
        <property type="entry name" value="YegS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00046">
        <property type="entry name" value="DAGKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="SSF111331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00147">
        <property type="entry name" value="TIGR00147"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50146">
        <property type="entry name" value="DAGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DAGKc" evidence="1">
        <location>
            <begin position="1"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="302" mass="32561" checksum="701EE277A5A4A7B9" modified="2019-10-16" version="1">MSHLLIWNQGSGRAAQIERLRSAMDADGTRCVELTRKVDLRSTIEESLQGSDDTVIAAGGDGTVNAIVNALMQIDRSRRPQMAVIPLGTANDFAGTLAIPDDIDQAVGLISAGRSVAIDVIRIRGEGLQQYYANVAAGGNCVRVSEELTDELKSRWGAFSYLRGAIGVLTDMKSFQIAAEIDGVEIKDFDSWAVLVANGKTNAGHIVVAPEASPADGLMDVILIRDGDATDMLEMIAGNLLGNFLECEQILFQKASRLTLRSTPAMRFTLDGEVIEQEPVEFQVMPAAIKMFVGPEFEQSNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVM8</accession>
    <name>A0A518IVM8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_31470</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="550" mass="62408" checksum="C20A76494166A043" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVS0</accession>
    <name>A0A518IVS0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">PA14 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Mal33_31760</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013039">
        <property type="entry name" value="DUF1588"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013042">
        <property type="entry name" value="DUF1592"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037524">
        <property type="entry name" value="PA14/GLEYA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011658">
        <property type="entry name" value="PA14_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13442">
        <property type="entry name" value="Cytochrome_CBB3"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="PSCyt3"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PSD4"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="1 4" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome c" evidence="6">
        <location>
            <begin position="74"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="PA14" evidence="7">
        <location>
            <begin position="189"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV57175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="806" mass="90007" checksum="1D12CEB96BF49D5A" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVV2</accession>
    <name>A0A518IVV2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_32260</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Rosistilla</taxon>
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    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="325" mass="36048" checksum="59443CCE9EF988FD" modified="2019-10-16" version="1">MNISQSIVTLGLLGSFCFSVQADEKGSVLDGVSIQRYVPQSGSLPACTHITRHGETEIVTSSDRLFYRTDAQSPLIRSPIDVLVDAHSVVFNPVEKLFYATDTGNHRLITFADPAGDTWDTFATSLAGIKLQRPHDIVFDDATGWMYALNPNSSEVFRFKGSGGDLAVLDLSKHLGYSRALTIANGTLYVIGSSHGVVVEVTDFEKQAFQIHTSFGKKKNAVAGSWQATGLVLNDVDYYQGHWYATSYFCLTYAGNEDCDEHKFIRFKTWDDLKTGRWDDLSSLLPSKIVPYFLTPHADGLDIAMFSHEARGQADWIYRLTLATH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IW45</accession>
    <name>A0A518IW45_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_33010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="92" mass="9810" checksum="64E6379C4C80E1D2" modified="2019-10-16" version="1">MTTLLAAAFGIHAFAIPVFGIAVLIASKLSLADKRFAESLFMAALTLVTLVTLRTVANNDPAWLTHTLTLAVMILGAVWLPSMNDIQAAKRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWB7</accession>
    <name>A0A518IWB7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Doubled CXXCH motif (Paired_CXXCH_1)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_33980</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036280">
        <property type="entry name" value="Multihaem_cyt_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010177">
        <property type="entry name" value="Paired_CXXCH_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09699">
        <property type="entry name" value="Paired_CXXCH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48695">
        <property type="entry name" value="SSF48695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Paired_CXXCH_1" evidence="1">
        <location>
            <begin position="333"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="604" mass="66800" checksum="3D64588CCC456890" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWC6</accession>
    <name>A0A518IWC6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATPase RavA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ravA_5</name>
        <name evidence="2" type="ORF">Mal33_34040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045427">
        <property type="entry name" value="MoxR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20030">
        <property type="entry name" value="bpMoxR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="bpMoxR" evidence="1">
        <location>
            <begin position="16"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="bpMoxR" evidence="1">
        <location>
            <begin position="320"/>
            <end position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="687" mass="77308" checksum="7A27256C027569F7" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWX7</accession>
    <name>A0A518IWX7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">DNA repair protein RecO</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6 7">Recombination protein O</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">recO</name>
        <name evidence="9" type="ORF">Mal33_36060</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in DNA repair and RecF pathway recombination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the RecO family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00201">
        <property type="entry name" value="RecO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037278">
        <property type="entry name" value="ARFGAP/RecO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022572">
        <property type="entry name" value="DNA_rep/recomb_RecO_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003717">
        <property type="entry name" value="RecO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042242">
        <property type="entry name" value="RecO_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33991">
        <property type="entry name" value="PTHR33991"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02565">
        <property type="entry name" value="RecO_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11967">
        <property type="entry name" value="RecO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57863">
        <property type="entry name" value="SSF57863"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00613">
        <property type="entry name" value="reco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4 7" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="5 7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA_rep/recomb_RecO_N" evidence="8">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00033409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF11967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV57594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="258" mass="28603" checksum="655D16EBA6B53438" modified="2019-10-16" version="1">MSSEKTEAIILRIVPFSESSVVLTMLTRDFGKISALAKGAYRPKSAFEGAIDLGCHCRVVFIKKSSDALDLLTEAKLERRFRAANKSLPQLYVGYYIFELLRELTESDEPHPDLFDLSLWTLKKIDSADLIPGELLDLVATFELQALKTLGHAPSMDVCATCGKTVADAARVAFGMISGGVLCDACRPRSRQVVMLSKQARDAMRQRIDEPGGARSANQTQKNQLNGELRGVLRRYMSHHVGHELKMPRLIDGIRVRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IX36</accession>
    <name>A0A518IX36_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">30S ribosomal protein S7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6 10" type="primary">rpsG</name>
        <name evidence="10" type="ORF">Mal33_36640</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the universal ribosomal protein uS7 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.455.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00480_B">
        <property type="entry name" value="Ribosomal_S7_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000235">
        <property type="entry name" value="Ribosomal_S5/S7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005717">
        <property type="entry name" value="Ribosomal_S7_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020606">
        <property type="entry name" value="Ribosomal_S7_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023798">
        <property type="entry name" value="Ribosomal_S7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036823">
        <property type="entry name" value="Ribosomal_S7_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11205">
        <property type="entry name" value="PTHR11205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00177">
        <property type="entry name" value="Ribosomal_S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002122">
        <property type="entry name" value="RPS7p_RPS7a_RPS5e_RPS7o"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47973">
        <property type="entry name" value="SSF47973"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01029">
        <property type="entry name" value="rpsG_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00052">
        <property type="entry name" value="RIBOSOMAL_S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 6 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 6 8" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="6" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_S7" evidence="9">
        <location>
            <begin position="6"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003620"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV57651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="156" mass="17977" checksum="7F9B00D049280905" modified="2019-10-16" version="1">MGRITASRSQLKPDPRFNSVLVSKFVNNLMHDGKKTVALNVFYNSLEEIKRRKADLEPFEVFEQAIENVKPHIEVRSKRVGGASYQVPMQVNRSRQQALAFRWILGAIRDKKGRPTHMKLADEFLAAYNKEGTAYTKRENTHRMADANKAFAHFAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IX68</accession>
    <name>A0A518IX68_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SWIM-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_36900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007527">
        <property type="entry name" value="Znf_SWIM"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50966">
        <property type="entry name" value="ZF_SWIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SWIM-type" evidence="2">
        <location>
            <begin position="55"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="484" mass="53833" checksum="418796CCFC1EBE75" modified="2019-10-16" version="1">MISIDQAFVDSEAPNSNAISNGRGLLVKGKFVALHKSDDDTILFGECSGSGRTNYHCSCDFITPGKVTYRCSCPSRQFPCKHCIGLMYAFTDGKPFSVASVPEDLAAKREKLEQRVEKKKADATKPRKVNKSALKKKIQAQLDGLTLLEQLTHELIRTGMGNTNAKTAKNIEQQAKQLGNAYLPGAQSALHAYTKLFSGDDGGFDSSVTPQQREAIYSQALDQLTQLNALIKNGRSYLNDRLADPELAAETQSTIAAWLGHAWQLRELKEAGLVQENAELIQLAFNSYDDIARRELVDTGIWMNLGDGRIGLTQNFRPYKALKYVKAEDSFFRIAQVPELCLYPGDINPRIRWDALTPRPVEASDLQAVRQHAHSNFAEILKTIKTHLKSPLADRRPIVALNYAQIGRVGDDLVVEDAAKTRIVFTETGQAEEPASCHLLQLLPPEMFQNQTLIGRFHHDLQARTLRVKPLSIVTASQVFRLTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IX87</accession>
    <name>A0A518IX87_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_37120</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetia</taxon>
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            <taxon>Rosistilla</taxon>
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    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
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    </dbReference>
    <dbReference type="InterPro" id="IPR006842">
        <property type="entry name" value="Transposase_31"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04754">
        <property type="entry name" value="Transposase_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transposase_31" evidence="1">
        <location>
            <begin position="9"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="312" mass="35394" checksum="5B338751DD908F33" modified="2019-10-16" version="1">MGGDESLPNPHDRFIRHFLAEIDHVRELITWQLPAAVVDELDLTSIQPAKQSFVNKTLRENLSDLVFNVRLAHDAGEAMVVLLFEHKSAPDEMTPFQVLRYMVEISQERHRNGQPLCCVIPIILYHGPQPWHVARSIPELIDVPAPLKPYIPQFSLPLIDLSQCSDEELRGKSIFLATMTLLKYIKRDELAEQLPGVLSLYRQLLPPATALESLEVVLRYLVNGTDRITREDLSTLVAKSLQHQGTSLMPTIAEQWLEEGREQGELIGKIQAFQAVLGRETSQRDELTKLSTAELKRIVDELTSAIEQNRSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXF5</accession>
    <name>A0A518IXF5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_37830</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="38" mass="4405" checksum="26283522DBE6132E" modified="2019-10-16" version="1">MKSNHDPGRSFFRHENIFWIVTIAVAIAIALLIVRRVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXM5</accession>
    <name>A0A518IXM5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NPCBM-associated, NEW3 domain of alpha-galactosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_38570</name>
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    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="Ig-like_fold"/>
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    <dbReference type="Pfam" id="PF01345">
        <property type="entry name" value="DUF11"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01451">
        <property type="entry name" value="B_ant_repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021747663" evidence="2">
        <location>
            <begin position="27"/>
            <end position="937"/>
        </location>
    </feature>
    <feature type="domain" description="DUF11" evidence="3">
        <location>
            <begin position="407"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="domain" description="DUF11" evidence="3">
        <location>
            <begin position="518"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="755"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="917"/>
            <end position="937"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="759"/>
            <end position="802"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV57842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="937" mass="99824" checksum="9B01076B29FEA545" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXM7</accession>
    <name>A0A518IXM7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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    <organism evidence="1 2">
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            <taxon>Planctomycetia</taxon>
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    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="component" value="Chromosome"/>
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        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
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        <property type="entry name" value="DUF1501"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07394">
        <property type="entry name" value="DUF1501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="459" mass="49984" checksum="7865221305E844D0" modified="2019-10-16" version="1">MLDLIGRGKAQTCNGTTRRDFLQVGTLGMLGLGLPSYVAAREAGKVDPAKDAHSCIMIFNLGAPSQLDTFDMKPDAPAEVRGPFKPISTASGEFQISEILPQHAKIADKFSLVRSCFHRGAAVHDAGWQMMQTGRLFTGGVNYPHAGAVVDYLRGRRSDLPAHVVLPETMGRGGGNLPNGQAGGFLGKRYDPFALMADPSQPNFQVPDLLPPDSIGQARIDRRRKMREIVEQTMTNFESSETAQLLDGSFESAYRMMTSPEARNAFDLAKEPMKVRERYGMNRFGQCCLLARRLIEGGVRFVTINTFLTVFNEITWDIHGSKPFTSIEGMRDIVAPMYDQGYSALIEDLADRGMIDSTLVACLAEFGRTPKVNPAGGRDHWPQCFTTYFAGGGVQGGRAIGASDPNGAVPAERPAAADEVVATIFHSLGLDLDTELPGPARRPFPLVNFGAREIHELFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXV2</accession>
    <name>A0A518IXV2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/beta hydrolase family protein</fullName>
        </submittedName>
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        <name evidence="3" type="ORF">Mal33_39240</name>
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    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="106"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="311" mass="34755" checksum="ACB489BFFE3058B7" modified="2019-10-16" version="1">MPAEEIVNPSQLESESQHETAPARRPYWNLARRCVRMSLAVVVGLYLAMLLMLTWLETSLVYPAPSVAAANWNRPDLQFEDVNFTSADGTALHGWYFEHPQPRAQLLFCHGNAQQVADLGDWISELRDLYQVSIFVFDYRGYGKSQGKPTETGVLQDGEAAQRWLAKRAGIADDEVIVWGLSLGGGIATHLASELGAKALILDRTFHSIVELAQSIYPWAPIRWLMRNRYPSVERIQNYRGPLLQIHGPIDEIVPFTSGKQLFDACPSEDKRFLELKNFGHLDSPTAEFYAAVGELIDSVADPQEPSSAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYC4</accession>
    <name>A0A518IYC4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Fatty acid oxidation complex subunit alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">fadJ_2</name>
        <name evidence="11" type="ORF">Mal33_41020</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>a (3S)-3-hydroxyacyl-CoA + NAD(+) = a 3-oxoacyl-CoA + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:22432"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57318"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:90726"/>
            <dbReference type="EC" id="1.1.1.35"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism; fatty acid beta-oxidation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00659"/>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003857">
        <property type="term" value="F:3-hydroxyacyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006180">
        <property type="entry name" value="3-OHacyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006176">
        <property type="entry name" value="3-OHacyl-CoA_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006108">
        <property type="entry name" value="3HC_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00725">
        <property type="entry name" value="3HCDH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02737">
        <property type="entry name" value="3HCDH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00067">
        <property type="entry name" value="3HCDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="4" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3HCDH_N" evidence="10">
        <location>
            <begin position="327"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="domain" description="3HCDH" evidence="9">
        <location>
            <begin position="508"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="domain" description="3HCDH" evidence="9">
        <location>
            <begin position="639"/>
            <end position="718"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QDV58085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="742" mass="81700" checksum="B4370DA1C270FE29" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYF8</accession>
    <name>A0A518IYF8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_41430</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022089426" evidence="1">
        <location>
            <begin position="21"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="369" mass="35955" checksum="0CC8B92C3FDE743F" modified="2019-10-16" version="1" precursor="true">MLRSLITLTLVMCGVLQLSADDANKSLRVKTASTTTLAAASNAFPEGLIANLDRDGRIQVQLLDLTAGKAGAAGNLAVTLVGVDGGVGHAVAGANGIASLQAPGAGWYSLVVADADQQKHGVLFIYANATGEAKTAPLAFPIVSVGEGAVLQNIRGYLGDVSGPFAPLAGINAYQIASGDFYRVQLASNGTLNGQVIAPLRADGQSIGSLESTNITIIQNGAAVKRTTVNSSGSFSVAGLKPGAYGVIAAGQLGYTAFSIEALATPTVQPVSTRANLQGGGLICCLAPASMMGPTMEAVSESFGESGGFANAGPGAPGPAAGGGGMTGGGGGGGGGGDIAALAALGAAAAVLAANDDDDDNFVASPAAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYG6</accession>
    <name>A0A518IYG6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Arginine biosynthesis bifunctional protein ArgJ</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="7">Glutamate N-acetyltransferase</fullName>
                <ecNumber evidence="7">2.3.1.35</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="7">Ornithine acetyltransferase</fullName>
                <shortName evidence="7">OATase</shortName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="7">Ornithine transacetylase</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="7">Amino-acid acetyltransferase</fullName>
                <ecNumber evidence="7">2.3.1.1</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="7">N-acetylglutamate synthase</fullName>
                <shortName evidence="7">AGSase</shortName>
            </alternativeName>
        </domain>
        <component>
            <recommendedName>
                <fullName evidence="7">Arginine biosynthesis bifunctional protein ArgJ alpha chain</fullName>
            </recommendedName>
        </component>
        <component>
            <recommendedName>
                <fullName evidence="7">Arginine biosynthesis bifunctional protein ArgJ beta chain</fullName>
            </recommendedName>
        </component>
    </protein>
    <gene>
        <name evidence="7 8" type="primary">argJ</name>
        <name evidence="8" type="ORF">Mal33_41460</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>L-glutamate + N(2)-acetyl-L-ornithine = L-ornithine + N-acetyl-L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:15349"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:44337"/>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
            <dbReference type="ChEBI" id="CHEBI:57805"/>
            <dbReference type="EC" id="2.3.1.35"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>acetyl-CoA + L-glutamate = CoA + H(+) + N-acetyl-L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24292"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:44337"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.1.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Amino-acid biosynthesis; L-arginine biosynthesis; L-ornithine and N-acetyl-L-glutamate from L-glutamate and N(2)-acetyl-L-ornithine (cyclic): step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 1/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 7">Heterotetramer of two alpha and two beta chains.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="7">Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the ArgJ family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.35" evidence="7"/>
    <dbReference type="EC" id="2.3.1.1" evidence="7"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00106"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004042">
        <property type="term" value="F:acetyl-CoA:L-glutamate N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004358">
        <property type="term" value="F:glutamate N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0103045">
        <property type="term" value="F:methione N-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02152">
        <property type="entry name" value="OAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01106">
        <property type="entry name" value="ArgJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002813">
        <property type="entry name" value="Arg_biosynth_ArgJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016117">
        <property type="entry name" value="ArgJ-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042195">
        <property type="entry name" value="ArgJ_beta_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23100">
        <property type="entry name" value="PTHR23100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01960">
        <property type="entry name" value="ArgJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56266">
        <property type="entry name" value="SSF56266"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00120">
        <property type="entry name" value="ArgJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="5 7" id="KW-0068">Autocatalytic cleavage</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_5023473115" description="Arginine biosynthesis bifunctional protein ArgJ alpha chain" evidence="7">
        <location>
            <begin position="1"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023473114" description="Arginine biosynthesis bifunctional protein ArgJ beta chain" evidence="7">
        <location>
            <begin position="183"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="7">
        <location>
            <position position="183"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="146"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="267"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="390"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="395"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole" evidence="7">
        <location>
            <position position="107"/>
        </location>
    </feature>
    <feature type="site" description="Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole" evidence="7">
        <location>
            <position position="108"/>
        </location>
    </feature>
    <feature type="site" description="Cleavage; by autolysis" evidence="7">
        <location>
            <begin position="182"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV58129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="395" mass="41560" checksum="478FAD20429B212E" modified="2019-10-16" version="1">MQLPQGFRFAGVRCGIKAKADRKDLTLVVGDRDLVAAGVYTQNKIVAAPVVLSRSRTPSSAVRAVVINSGNANACTGQQGDRDALAMTNLVAKACELDPSSVLVMSTGIIGHKLPMDRIEQGIQSAADQLNDSSDNFLAAADGILTTDQGRKLAFRCEQIGDQKITFAAMAKGAGMIGPNMATMLGLVLCDANLSKIDAQRALRVAADASFNSISVDGHTSTNDTVNLLCSGTASATPLSEEHLARFTEVLTDFCIELAKQIPADGEGAHHVIEIRVGGADCDADAKQIAKSIADSPLVKTAVTGNDPNWGRIMSAAGYAGVLVRPELCQLKINGSMVFDKGQPIDFDEKAISESMAADRTVVLQVTVGDGPGTSVFWTSDLTTDYVTFNSDYST</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYJ5</accession>
    <name>A0A518IYJ5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">prkC_10</name>
        <name evidence="10" type="ORF">Mal33_41820</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011852">
        <property type="entry name" value="TRAP_TAXI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16868">
        <property type="entry name" value="NMT1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="427"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="119"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="148"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV58165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="720" mass="77757" checksum="D15B187F438C1ED5" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYK4</accession>
    <name>A0A518IYK4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">FtsX-like permease family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Mal33_41870</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
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            <end position="291"/>
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    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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            <end position="337"/>
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    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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            <end position="379"/>
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    <feature type="transmembrane region" description="Helical" evidence="6">
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    <feature type="transmembrane region" description="Helical" evidence="6">
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    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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            <end position="770"/>
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    <feature type="domain" description="FtsX" evidence="7">
        <location>
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            <end position="385"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="7">
        <location>
            <begin position="687"/>
            <end position="773"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV58170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="787" mass="86508" checksum="1CF29ECFE3E402D9" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYV7</accession>
    <name>A0A518IYV7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 14">Inosine-5'-monophosphate dehydrogenase</fullName>
            <shortName evidence="7">IMP dehydrogenase</shortName>
            <shortName evidence="7">IMPD</shortName>
            <shortName evidence="7">IMPDH</shortName>
            <ecNumber evidence="7 14">1.1.1.205</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 17" type="primary">guaB</name>
        <name evidence="17" type="ORF">Mal33_42910</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 14">
            <text>H2O + IMP + NAD(+) = H(+) + NADH + XMP</text>
            <dbReference type="Rhea" id="RHEA:11708"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57464"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="EC" id="1.1.1.205"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="7">Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7 14">Purine metabolism; XMP biosynthesis via de novo pathway; XMP from IMP: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 13">Belongs to the IMPDH/GMPR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.205" evidence="7 14"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00601">
        <property type="reaction ID" value="UER00295"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003938">
        <property type="term" value="F:IMP dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006177">
        <property type="term" value="P:GMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00381">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01964">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005990">
        <property type="entry name" value="IMP_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015875">
        <property type="entry name" value="IMP_DH/GMP_Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001093">
        <property type="entry name" value="IMP_DH_GMPRt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11911">
        <property type="entry name" value="PTHR11911"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00478">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01302">
        <property type="entry name" value="IMP_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00487">
        <property type="entry name" value="IMP_DH_GMP_RED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12" id="KW-0129">CBS domain</keyword>
    <keyword evidence="3 7 14" id="KW-0332">GMP biosynthesis</keyword>
    <keyword evidence="2 7 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 10 14" id="KW-0520">NAD</keyword>
    <keyword evidence="5 7 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 7 11" id="KW-0630">Potassium</keyword>
    <keyword evidence="7 14" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="16">
        <location>
            <begin position="95"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="16">
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            <begin position="155"/>
            <end position="212"/>
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    </feature>
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        <location>
            <begin position="336"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="IMP binding" evidence="7 9">
        <location>
            <begin position="359"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="IMP binding" evidence="7 9">
        <location>
            <begin position="383"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="472"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="active site" description="Thioimidate intermediate" evidence="7 8">
        <location>
            <position position="303"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7 8">
        <location>
            <position position="399"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="247"/>
            <end position="249"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="247"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 10">
        <location>
            <begin position="296"/>
            <end position="298"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 11">
        <location>
            <position position="298"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 11">
        <location>
            <position position="300"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="301"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 11">
        <location>
            <position position="303"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="413"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="467"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <note>ligand shared between two tetrameric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="469"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <note>ligand shared between two tetrameric partners</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022749"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
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            <dbReference type="HAMAP-Rule" id="MF_01964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000130-1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PIRSR" id="PIRSR000130-2"/>
        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="PIRSR" id="PIRSR000130-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU003928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="QDV58273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="493" mass="53250" checksum="CD07ACB054A89503" modified="2019-10-16" version="1">MSQEKLIQEGFTFDDVLLTPQYSAVVPSEVDTSTHLTSKIRLQIPLISSPMDTVTESEMAIALAKVGGLGVIHKNLSIEAQTEEVLKVKRSANGIIFDPVTLHPDEKVSRAQELMDQKNVSGIPIVYSDGKLAGILTRRDLRFLESPDRLISEVMTHENLVTAVGNVTLEEAERILTEKRVEKLLLVDEERILTGLITIKDIDMMQRFPSASKDGQGRLRVGAAIGVHDYERAESLINQGVDILTVDSAHGHSKNVIETVKKLKQQWQIDLIAGNVATADGARDLIDAGVDAIKVGIGPGSICTTRVISGVGVPQVTAIMEAARVANERNIPIIADGGIRFSGDITKAIAAGAKVVMIGSLFAGLTESPGKMILYQGRTFKAYRGMGSIGAMAQGSSERYRQSATESGKLVPEGVEGRVPFKGPLSEYVFQLVGGLRAGMGYIGTQTIEELRTRARFIKVSAATVRENHPHDIAITQEAPNYSPEVHHSGDSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ46</accession>
    <name>A0A518IZ46_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Methylenetetrahydrofolate reductase</fullName>
            <ecNumber evidence="10">1.5.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">metF</name>
        <name evidence="11" type="ORF">Mal33_43760</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2 10">
            <text>(6S)-5-methyl-5,6,7,8-tetrahydrofolate + NAD(+) = (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:19821"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:18608"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.5.1.20"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>(6S)-5-methyl-5,6,7,8-tetrahydrofolate + NADP(+) = (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:19817"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:18608"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.5.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3 10">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4 10">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 10">Belongs to the methylenetetrahydrofolate reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.20" evidence="10"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00193"/>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106312">
        <property type="term" value="F:methylenetetrahydrofolate reductase NADH activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106313">
        <property type="term" value="F:methylenetetrahydrofolate reductase NADPH activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00537">
        <property type="entry name" value="MTHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029041">
        <property type="entry name" value="FAD-linked_oxidoreductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003171">
        <property type="entry name" value="Mehydrof_redctse-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004620">
        <property type="entry name" value="MTHF_reductase_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02219">
        <property type="entry name" value="MTHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51730">
        <property type="entry name" value="SSF51730"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00676">
        <property type="entry name" value="fadh2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0274">FAD</keyword>
    <keyword evidence="6 10" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9" id="KW-0520">NAD</keyword>
    <keyword evidence="8 10 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00006743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QDV58358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="288" mass="31540" checksum="A55BAC5023852085" modified="2019-10-16" version="1">MSLSQLFRGGGCPISFELFPPRTPAGFESLYQHVDSLKQFDPAFFTCTYGAGGSTRDSTLDVVREVKRRTGKPVASHLTCVGSTQDQLRSYLTEAGTLGVDYIVALRGDPPKGETSFTAVEGGFRFANELVEMIHAEFPEFGIAVAGYPEVHQEAVDADVDMENLKRKVDAGADCVVTQLFYDNDDFFRFRDACQAAGIEIPIIPGLLPITNFAQAQRIASMCKAKLPQGLVDRFNENDSAEWQLKVGIEHAQQQTNDLIRRGIDGLHLYVLNKSQAAAEVLAGVDRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ58</accession>
    <name>A0A518IZ58_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Fatty acid desaturase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Mal33_43870</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016717">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03505">
        <property type="entry name" value="Delta9-FADS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015876">
        <property type="entry name" value="Acyl-CoA_DS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11351">
        <property type="entry name" value="PTHR11351"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00075">
        <property type="entry name" value="FACDDSATRASE"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="75"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="101"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="224"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="258"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="domain" description="FA_desaturase" evidence="9">
        <location>
            <begin position="106"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="34"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV58369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="363" mass="41237" checksum="DEFE47518396A9C1" modified="2019-10-16" version="1">MPTEPAQHKLASHRSGPIQAPLIPKIPDLIMSTEAIEAPDQESDDSNPSAANASGRPPRVDIPETAKPPQLQVSYALVIGLVHVAALMVAIPPMAGYLFSWSGLVLAIAGHFFYGMIGINVCYHRLLTHRGFKCPLWLEHSLAVLGICNLQDSPARWVAIHRMHHQHSDHQPDPHTPKAGFWWSHVGWVLYRNRDHDTTSHFERYVRDLLRDPFYLKLEARWRWFGIFATHALLYYLIGSAVGYFMTGTLAGAVQLGLSWFFWGVMVRVVIVLHGTWAVNSLTHVIGYRNYETRDDSRNHWLIAMLTHGEGWHNNHHASPRAAMHGHRWWEYDMAWSVIRMMEIVGLATDVVRPGKTAEPADW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ99</accession>
    <name>A0A518IZ99_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ATP-dependent dethiobiotin synthetase BioD</fullName>
            <ecNumber evidence="5">6.3.3.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">DTB synthetase</fullName>
            <shortName evidence="5">DTBS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Dethiobiotin synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">bioD1</name>
        <name evidence="5" type="synonym">bioD</name>
        <name evidence="6" type="ORF">Mal33_44270</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>(7R,8S)-7,8-diammoniononanoate + ATP + CO2 = (4R,5S)-dethiobiotin + ADP + 3 H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:15805"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:149469"/>
            <dbReference type="ChEBI" id="CHEBI:149473"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.3.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5">Cofactor biosynthesis; biotin biosynthesis; biotin from 7,8-diaminononanoate: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the dethiobiotin synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.3.3.3" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00078">
        <property type="reaction ID" value="UER00161"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004141">
        <property type="term" value="F:dethiobiotin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009102">
        <property type="term" value="P:biotin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00336">
        <property type="entry name" value="BioD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004472">
        <property type="entry name" value="DTB_synth_BioD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43210">
        <property type="entry name" value="PTHR43210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006755">
        <property type="entry name" value="DTB_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00347">
        <property type="entry name" value="bioD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 5" id="KW-0093">Biotin biosynthesis</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="5">
        <location>
            <position position="38"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="13"/>
            <end position="18"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="17"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="116"/>
            <end position="119"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="116"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="177"/>
            <end position="178"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="202"/>
            <end position="204"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV58409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="232" mass="24617" checksum="A80F7D172C3057C2" modified="2019-10-16" version="1">MGSLTFIAGTDTDVGKTFVSSLLAAAILQRGLPVGVYKPVASGCWLEQDELVSGDAVALWQAAGKPLDLEHVCPQRFAAALSPPRAAEAEGKLVDVDRILSGLSPWTEGFDHVLIEGAGGLLSPLADDFLNADLAGELEADVILVAANRLGVVNHTLLSVEVCRSRLGRDPIAIVLNQVGREGCESMKTNRGEIQRYVGRMPIIEVGFEQQSLLESAGAEEFIGRTLRTPSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZE1</accession>
    <name>A0A518IZE1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="17">Cytochrome c oxidase subunit 2</fullName>
            <ecNumber evidence="17">1.9.3.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">ctaC_2</name>
        <name evidence="17" type="ORF">Mal33_44740</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome c oxidase subunit 2 family.</text>
    </comment>
    <dbReference type="EC" id="1.9.3.1" evidence="17"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070469">
        <property type="term" value="C:respirasome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004129">
        <property type="term" value="F:cytochrome-c oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04213">
        <property type="entry name" value="CuRO_CcO_Caa3_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045187">
        <property type="entry name" value="CcO_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002429">
        <property type="entry name" value="CcO_II-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001505">
        <property type="entry name" value="Copper_CuA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034236">
        <property type="entry name" value="CuRO_CcO_Caa3_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014222">
        <property type="entry name" value="Cyt_c_oxidase_su2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22888">
        <property type="entry name" value="PTHR22888"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00116">
        <property type="entry name" value="COX2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00034">
        <property type="entry name" value="Cytochrom_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="SSF49503"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02866">
        <property type="entry name" value="CoxB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00078">
        <property type="entry name" value="COX2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50857">
        <property type="entry name" value="COX2_CUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0186">Copper</keyword>
    <keyword evidence="8" id="KW-0249">Electron transport</keyword>
    <keyword evidence="4 13" id="KW-0349">Heme</keyword>
    <keyword evidence="10 13" id="KW-0408">Iron</keyword>
    <keyword evidence="12 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="6 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="55"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="COX2_CUA" evidence="15">
        <location>
            <begin position="89"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="16">
        <location>
            <begin position="215"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="QDV58451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="307" mass="33704" checksum="EAE120480A607812" modified="2019-10-16" version="1">MPQSTLQPAGEAAEAIALLFYWMSAGAVVIWIIVVGLAVYAIYQPGQHHPQTIKRWVIGGGAVFPTIVLTGLLCVSLPMMPELQRPAPQGSLQVHVSGVRWWWRITYQIDDETVVETANEIRLPVGRPVEFKLDSEDVIHSFWIPALGGKVDMMPGRQTRLKLHPTRVGTFRGVCAEFCGAAHAQMNFDVVVMPADEFDAWLKQLTRPTASSQEPDAVAGEKHFFAVGCHACHTIRGTDANGSMGPDLTHFGSRPSIAAGLLPNNHANLVRWITETDRVKPGVDMPAFHAMERQQADEIAAFLEGLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZL8</accession>
    <name>A0A518IZL8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Biofilm growth-associated repressor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">bigR</name>
        <name evidence="2" type="ORF">Mal33_44980</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01022">
        <property type="entry name" value="HTH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00778">
        <property type="entry name" value="HTHARSR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50987">
        <property type="entry name" value="HTH_ARSR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="19"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="109" mass="11552" checksum="0FB357F0CE7B068E" modified="2019-10-16" version="1">MAKKSSVKQGCDSTPVKLAADASATDFAKLAWAIAHPARVQIVRLLIGRKACVCGDIVAQLPLAQSTVSQHLKILKESGLIQGEVDGPKVCYCINADRLARLKELVAGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZR3</accession>
    <name>A0A518IZR3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Transport protein TonB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Mal33_46020</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
            <orientation evidence="1">Periplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TonB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006260">
        <property type="entry name" value="TonB/TolA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037682">
        <property type="entry name" value="TonB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03544">
        <property type="entry name" value="TonB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01352">
        <property type="entry name" value="tonB_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022032126" evidence="10">
        <location>
            <begin position="24"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_C" evidence="11">
        <location>
            <begin position="141"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="117"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="117"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF03544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QDV58579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="218" mass="23810" checksum="C38801BF8E27797C" modified="2019-10-16" version="1" precursor="true">MNLYFRSTSFAFAVHASALVAMCAVPLAVSERFTSSGQRNVISIQLSIAQPAAVESVAMTIEPTPPLPREDPIEFQPVQHSTLSRRALAPPTPPEVTPQTMPVMRRAVASRMRPPAATTIPIQQQTGLSEKEPASFTANEPPQYPSQAVRDRLQGTVLLRLFVDSTGRVEAVELIESSGHATLDDAAMEAVKKWTGQPARRYGRPVASEEVLPIRFRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZS7</accession>
    <name>A0A518IZS7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type I phosphodiesterase / nucleotide pyrophosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_46170</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002591">
        <property type="entry name" value="Phosphodiest/P_Trfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01663">
        <property type="entry name" value="Phosphodiest"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022096430" evidence="1">
        <location>
            <begin position="28"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="461" mass="48783" checksum="1586D222A63597E5" modified="2019-10-16" version="1" precursor="true">MQTIPRLLCVAAVAAAACCFSALSAHAAGPTKHVVVVSLDGLAAYLVDDPKVPLPTIRRLAREGSIVAGGMIPSNPSVTWPNHTTLVTGARPEKHGVLANGVLVRGPIGVPTTIDSRRDQSDLVRIPTIVDAAHAAGLSTAEINWPCTRGSKSFDDQFPDVPDALQHSTPRLRKELVELGLLTDETDASFRKLSTVGRDYVWTEAACHLIRTRKPNLTLIHLLNVDSVHHNRGPQTPEGYTANAYADMCLARIVAAIDEAGIRDQTTLIVLSDHGFTRTPKAVRPNVLLSQAGLLKAEAGKIREAQVHVVPEGGIGLVYCTNPGEAAQQANAFKKMFVGLEGVADVVLPDGFAEIGLLHPREYNQSPDAVLVAADGYSVSGSVDGETLVASNTEAKTAIGSHGFVSTLPKMKALCLLSGAGIRSGIELPTIENIDIAPTIAKLLALEYPYSDGKPLTAAMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J009</accession>
    <name>A0A518J009_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Trehalose import ATP-binding protein SugC</fullName>
            <ecNumber evidence="5">3.6.3.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">sugC</name>
        <name evidence="5" type="ORF">Mal33_47070</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.6.3.-" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="2"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="33"/>
            <end position="40"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV58683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="217" mass="23642" checksum="6C52F8816754EF86" modified="2019-10-16" version="1">MMELSDVSVAAGTFSLRGLSLRIETGEYAVLMGKTGIGKTTILETICGLRKLGGGKIRIAGVDVSGWSAADRNVGYVPQDLALFPTMTVGQHLEFALRFRKVPRRQRAIRVGEMAKTLQIESLLDRKVDGLSGGEAQRVALGRALTFSPSVLLLDEPLSALDAETRQNVQAILRQINRKTGVTVLHVTHSQGEAESLADRWFCLERVDGAARIQERS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J018</accession>
    <name>A0A518J018_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HTH HARE-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_47200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1250">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007759">
        <property type="entry name" value="Asxl_HARE-HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038087">
        <property type="entry name" value="RNAP_delta_N_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05066">
        <property type="entry name" value="HARE-HTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51913">
        <property type="entry name" value="HTH_HARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="HTH HARE-type" evidence="3">
        <location>
            <begin position="56"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV58696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="127" mass="13434" checksum="1D651BB41C1A8FAB" modified="2019-10-16" version="1">MPTKKTTAATKTTATKNASAKKPATKKPAATKTAKATLAKKPAATKSAAKKADKKMSQIDAALTVLKKSRKPLSCKEMVEAMAKAKLWTSPGGKTPDATLYAAILRDMRKGKDARFKKAAPGRFTNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0M8</accession>
    <name>A0A518J0M8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_49140</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021832351" evidence="1">
        <location>
            <begin position="20"/>
            <end position="601"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="601" mass="66118" checksum="486408BD67874475" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0N4</accession>
    <name>A0A518J0N4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Corrinoid ABC transporter substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_49280</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002491">
        <property type="entry name" value="ABC_transptr_periplasmic_BD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01497">
        <property type="entry name" value="Peripla_BP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50983">
        <property type="entry name" value="FE_B12_PBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe/B12 periplasmic-binding" evidence="1">
        <location>
            <begin position="2"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="305" mass="33108" checksum="ACB90BB90BAE2B9F" modified="2019-10-16" version="1">MRIVSLLPSATEIICGLGLRDQLLGVTHECDYPTDVLNLPKVTQTLIPTDASSKQIDSLVRERVKTEYALYSLDMPVFESLSPDLIVTQTLCDVCAVSQREVSDAACALPNAAQLLNLEPTCLADVLDSIGQVAAAAGCVAQGERYRQSLQQRIDAVARRSKSIAPRPRVMLLEWVDPPFSAGHWSPELVAIAGGEEVIGVAGERSKTTPWETILAADPEVMIIACCGFDLARTQQDLPILRSYRGWERLSCVRNNRVYMVDGSAYFSRPGPRLVDSLEILAHALHPDTHPLPAGLSAAVAVAPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0S0</accession>
    <name>A0A518J0S0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phytanoyl-CoA dioxygenase (PhyH)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_49620</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008775">
        <property type="entry name" value="Phytyl_CoA_dOase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05721">
        <property type="entry name" value="PhyH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="240" mass="26424" checksum="C33EAEC6AE4E2B9C" modified="2019-10-16" version="1">MDEWDLRRDGFCMLRQAVCHASIARLLAVCGTAFEGETKSVRARSSRGHVYAARNLIESITDVTTVWQCEVLLSFLRQQLGADFGLVRALFFDKPPDRTWGLAWHKDMSIAVKDNSFTSASFSRPTVKAGVPHVIACDDVLSQLLTLRIHLDEVTAENGPLRVIPGSHRSSDTTGESLETAVDIHAAEGDVLAMRPLISHSSGASTPGTRRHRRILHLEFAPSPSLPDGMEWHDFVAPDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0X5</accession>
    <name>A0A518J0X5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Type II secretion system protein G</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">xcpT_15</name>
        <name evidence="1" type="ORF">Mal33_50070</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011453">
        <property type="entry name" value="DUF1559"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07596">
        <property type="entry name" value="SBP_bac_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="341" mass="37335" checksum="42C4643A6C571C08" modified="2019-10-16" version="1">MKRLPYLSPSGKRSRAGFTLVELLVVIAIIGILVGLLLPAVQAAREAARRMSCSNNMKQIGLALHMHHDTLQRFPSQRDQAKAPVPPSEQSFYRWGPLALLTPYLEQSAIYQAIDLQQPLLIFSMGPPPSVVTHPDLGDAVATQVSTFLCPSDVHERISDEWGATNYHANNGTAQDGGLYVNCDGLFYIDSQKRFRDILDGTSHTAAFSETLIGSGSPDSTRGVANSGPEGLLASVWDASSPTIDDSWCLNDSSPVIFRRGEKWADGSVNDTGYHHFHGPNAVENDCYSRYAARKSARSRHPGGVMLLMADGSVRFVTESIDRYTWQLIGSIADNEVIPEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J105</accession>
    <name>A0A518J105_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_50430</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="34" mass="3558" checksum="4F08416BC60EB7B3" modified="2019-10-16" version="1">MTNSDNNAVHTEPPIAWFANGERFSGGPVTAGVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J191</accession>
    <name>A0A518J191_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_51370</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="344" mass="39203" checksum="B89F6966A4318147" modified="2019-10-16" version="1">MKFDFSAQFLRVNPPETNFGDAWESLCYTLLDAELNDPSLIRLRPPDKGVDILHRSARRAFQCKSNEQGAFGTMSSTESVKSLKRGVGEREALGWNSYVLATNANYTGSAYTTIRETATELGLDDDQLDLFGPEHWDKLCVRHTDLIADRFDYRIPVPKPRVVKAFENQRYYPNYVSQYSDQVQKSDLVVRITNNRTAAVLEVPFSPDLTVKHLVDVVKDVLGVSLDWTNYHDLGTSAGPSIALTLDQKKQTFKTKIGDLNLGPDQEMQFWITLVWRDQRRDDGGDASGHMHFELLRHRMEFKTTDRDALSYGERKARTIERSEEIIETMLWNGARTLKSTNAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1L7</accession>
    <name>A0A518J1L7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Phosphoenolpyruvate carboxykinase (ATP)</fullName>
            <shortName evidence="8">PCK</shortName>
            <shortName evidence="8">PEP carboxykinase</shortName>
            <shortName evidence="8">PEPCK</shortName>
            <ecNumber evidence="4 8">4.1.1.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8 9" type="primary">pckA</name>
        <name evidence="9" type="ORF">Mal33_52570</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + oxaloacetate = ADP + CO2 + phosphoenolpyruvate</text>
            <dbReference type="Rhea" id="RHEA:18617"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="4.1.1.49"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="8">Binds 1 Mn(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.49" evidence="4 8"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00138"/>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004612">
        <property type="term" value="F:phosphoenolpyruvate carboxykinase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00484">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.449.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.228.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00453">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001272">
        <property type="entry name" value="PEP_carboxykinase_ATP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013035">
        <property type="entry name" value="PEP_carboxykinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008210">
        <property type="entry name" value="PEP_carboxykinase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30031">
        <property type="entry name" value="PTHR30031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01293">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006294">
        <property type="entry name" value="PEP_crbxkin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68923">
        <property type="entry name" value="SSF68923"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00224">
        <property type="entry name" value="pckA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="8" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="7 8 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-0464">Manganese</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="8">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="191"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="197"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="216"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="233"/>
            <end position="241"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="254"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="282"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="319"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="438"/>
            <end position="439"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="444"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV59229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="529" mass="58171" checksum="254A210944E6E33B" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1S4</accession>
    <name>A0A518J1S4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Mal33_53110</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the UPF0718 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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            <dbReference type="EMBL" id="QDV59283.1"/>
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            <dbReference type="Proteomes" id="UP000316770"/>
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<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
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                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
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                <person name="Lage O.M."/>
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        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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                <person name="Jogler M."/>
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                <person name="Kallscheuer N."/>
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                <person name="Kaster A.-K."/>
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                <person name="Rohde M."/>
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                <person name="Jogler C."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mal33</strain>
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        <reaction evidence="1">
            <text>acetyl-CoA + H2O + pyruvate = (3R)-citramalate + CoA + H(+)</text>
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        </reaction>
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    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-isoleucine biosynthesis; 2-oxobutanoate from pyruvate: step 1/3.</text>
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    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="HMGL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08502">
        <property type="entry name" value="LeuA_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="citramal_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="PYR_CT"/>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0412">Isoleucine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9 11" id="KW-0808">Transferase</keyword>
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        <location>
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        </location>
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    </evidence>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
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    </evidence>
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        <source>
            <dbReference type="RuleBase" id="RU003523"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50991"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="QDV59343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="526" mass="57493" checksum="6BA0B7B6E51A61ED" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1Z9</accession>
    <name>A0A518J1Z9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_53910</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
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    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009937">
        <property type="entry name" value="Phage_holin_3_6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07332">
        <property type="entry name" value="Phage_holin_3_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="39"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="71"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="134"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV59363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="162" mass="17290" checksum="8EA74E6EAD577A6D" modified="2019-10-16" version="1">MNSPSGFGRVARDVLDLCELQMQLLSVDSQEAKRKATRAMVTAAAGITLGGSALTTAMVGGSFLLHEYAQWSVGASLLCVAGITFGIVAALLFAATKAITSASAALQETKSEFAENLKWLKAVLINPETSARNQLRAESFPDPNPSHRAKASTYERPVYNER</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J227</accession>
    <name>A0A518J227_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DsbD_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_54290</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039447">
        <property type="entry name" value="UreH-like_TM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13386">
        <property type="entry name" value="DsbD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="140"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="173"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="202"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="DsbD_2" evidence="2">
        <location>
            <begin position="8"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV59394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="276" mass="28637" checksum="83FB14124F4A02BE" modified="2019-10-16" version="1">MWILATAIVTASLLGSMHCVGMCGPLAIWASGASENVSRRRVMTAGALYHIGRLITYALAGLIAGAIGSLIDFGGAAMGYQLLAARVVGAIMILIGIHRLISIIAPRKTDATEGPAPSRIGGLLVRLRPYVFRLPLPGRALATGLLTTLLPCGWLYLFALVAAGTGSLTMGPVVMIAFWIGTVPALVALVAGTQFLSRRFTMAIPAFAAVMLVVGGCYTASGRGFANLGSLTSLQASVEASAENNDDIDAQIQAIAKTPLPCCQVTPPVQDTDETK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J2A5</accession>
    <name>A0A518J2A5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative sulfoacetate transporter SauU</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">sauU_2</name>
        <name evidence="7" type="ORF">Mal33_55030</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="13"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="55"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="88"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="172"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="239"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="272"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="308"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="333"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="370"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="405"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="17"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV59468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="430" mass="46782" checksum="07151A37459584E4" modified="2019-10-16" version="1">MTMESDSESPTRIRYHVIGATTLAAVMLYLDRICIAEIAKLQEFRQALQLSDEQVGMVMSAFFFSYALAQVPAGWLSDRFGARRMMPIYIAVWSICTLLTGFANGFVMLLVVRLLFGLSQAGCYPAAGSLVKRWIELPRRGTASSIVSFGGRLGGAISPLLTAWLLKDYLNWQAVLALYGVGGLFVAVHFWRVFRETPMQHPACNAAEREVITQFDSPDDGGSSAAFPPILTLVGSGTMWLMCALQFGINIGWVFLVTWLPTYLQDVKQVDATIGGLMSTIVLFAGIGGMLLGGPLTDFCTQRLGTRWGRSLPIAGCSAVALCAYLSCLHLESAWSFVIAASIVAFMTDMSVPAVWAYMQDVGGKNTAAVFGWGNMWGNFGAAVTPLLVPIVLKKWDHNGDWHEAFYLFSAGYLVAALCALGINAQRKIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J2D1</accession>
    <name>A0A518J2D1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_55310</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012020">
        <property type="entry name" value="ABHD4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005211">
        <property type="entry name" value="Ab_hydro_YheT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="64"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV59496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="331" mass="36655" checksum="4B9ECB177A7D49DB" modified="2019-10-16" version="1">MSLSFQPHPLLLGGHLQTLATTLIPTPQIPYRATQHRVVLDDGDQIVLHDDTPPGWTPGQPVAILLHGLCGCHGASYMIRMADKLNRRGVRVFRMDMRGCGAGRDLARGLPHSGRSGDLLAAITRIADLCDDSPIWPIGISMGGNILLKMLGEIGKGILVPEFPADRIARAAAVAPPIDPARCCRNMSRWMMRPYGLYFIRKLRSRVAPLVEQREDWRAINWNPHPRTLWDFDGLVTAPLSGFRDVEDYYAQAAAAPLASGIAVPTMILASEDDPIIPIGCLREADWPGHVELHTTRRGGHVGFIGGRQLETGDRYWMDAKLLNWFDFPQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J2E6</accession>
    <name>A0A518J2E6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_55420</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="SSF75005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021813331" evidence="1">
        <location>
            <begin position="25"/>
            <end position="485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="485" mass="54552" checksum="DC8483D9AE5B1918" modified="2019-10-16" version="1" precursor="true">MRYPRNRMLPALVILASLTASSHAAEPLMLGSRWELFVDEYLIDSKQNVELKLHEPVRREIVLTTDKPWEGPTSAYFSVVQDGEKVRLYYRGSDGGPDHSESQFTCVAESEDGIHFTRPNLGLIEAGGTKENNVIWRGVESHNFAPFLDANPSAKPDARFKALGGVKMPGKNWQYGDTPGGLYAFASADGIHWRKLQKEPVITKGAFDSQNLAFWDAARNRYACFSRIFSVEDQLRAIQSSHSQDFLKWSTGVPHRYAEDAPKEHFYTSATIPCPTAPHLFLSFPKRFQPARRKIPEHSVKGVSDTIFMSSRDGVHWDRPFLQAWARPGLDPKNWTDRSNMVAYGIYDGGDGEWSLYISEHYRHADHRIRRLTVRQQGFASAHVGGGKHGEFTTHPIQFDGDSLQLNYASSAAGSIQIEIQDEKGQPIPGFTMQEMPELFGDELAATATWNSGSDLSSLRGKTIRLRVKMIDADLYALRFTDNVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J2G5</accession>
    <name>A0A518J2G5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ</fullName>
            <ecNumber evidence="1">4.2.1.59</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">fabZ_4</name>
        <name evidence="1" type="ORF">Mal33_55560</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="4.2.1.59" evidence="1"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008659">
        <property type="term" value="F:(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008693">
        <property type="term" value="F:3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047451">
        <property type="term" value="F:3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004317">
        <property type="term" value="F:3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013114">
        <property type="entry name" value="FabA_FabZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30272">
        <property type="entry name" value="PTHR30272"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07977">
        <property type="entry name" value="FabA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="166" mass="18710" checksum="ECA16F861687D23E" modified="2019-10-16" version="1">MRYSQLDEIVALQPGIQLIARRTLHASEDYLLDHFPRFPVMPGVMMLEALYQAAMWMVRTGEDFASPHVFLVEAKSVKFGDFLCPGETLEIKADKFKEDGPLVTVKAQATKGDKVTVSARLILERSGSEASPHNNDDDTRRFVREQFFNMFGDQPAVIQAMTQSTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IM25</accession>
    <name>A0A518IM25_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Endonuclease III</fullName>
            <ecNumber evidence="5">4.2.99.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">DNA-(apurinic or apyrimidinic site) lyase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">nth</name>
        <name evidence="7" type="ORF">Mal33_00940</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-monophospho-2'-deoxyribonucleoside-DNA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66592"/>
            <dbReference type="Rhea" id="RHEA-COMP:13180"/>
            <dbReference type="Rhea" id="RHEA-COMP:16897"/>
            <dbReference type="Rhea" id="RHEA-COMP:17067"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:136412"/>
            <dbReference type="ChEBI" id="CHEBI:157695"/>
            <dbReference type="ChEBI" id="CHEBI:167181"/>
            <dbReference type="EC" id="4.2.99.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="5">Binds 1 [4Fe-4S] cluster.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the Nth/MutY family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="4.2.99.18" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140078">
        <property type="term" value="F:class I DNA-(apurinic or apyrimidinic site) endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019104">
        <property type="term" value="F:DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00056">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1670.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00942">
        <property type="entry name" value="Nth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004036">
        <property type="entry name" value="Endonuclease-III-like_CS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003265">
        <property type="entry name" value="HhH-GPD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023170">
        <property type="entry name" value="HhH_base_excis_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000445">
        <property type="entry name" value="HhH_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005759">
        <property type="entry name" value="Nth"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00633">
        <property type="entry name" value="HHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00730">
        <property type="entry name" value="HhH-GPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00478">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="SSF48150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01083">
        <property type="entry name" value="nth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01155">
        <property type="entry name" value="ENDONUCLEASE_III_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3 5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="4 5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-0540">Nuclease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ENDO3c" evidence="6">
        <location>
            <begin position="39"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV54148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="217" mass="24255" checksum="98A99B830FBDD895" modified="2019-10-16" version="1">MRKQERAEIVLKRLNELYPDPPIPLDHRDPFTLLIAVLLSAQCTDKMVNRVTPALFDLADTPEAMRQQSVDAILEIIRPLGLAPKKAAAIAGLSQQLVDEFDGQVPADFKGLESLPGVGHKTASVVMSQAFGHPAFPVDTHIHRLAQRWGLTDGKNVQQTERDLKALFPESSWNALHLQIIYYGREYCTARGCDGTRCELCTTLYPKRRKPVETKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IM57</accession>
    <name>A0A518IM57_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_01310</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="38" mass="4365" checksum="D27A324EA2A55358" modified="2019-10-16" version="1">MTFAFVIKDEAHSNILRNATTETAIVFRQNDQGRIVRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMB3</accession>
    <name>A0A518IMB3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_01790</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="103" mass="10891" checksum="739DAEE5BAD48468" modified="2019-10-16" version="1">MAKKKATKKKVTKKAVAKKAPAKKATAKKAPAKKKAAVKKAPVKKAAAKKAPAKKKTTTKKAPVKKKAVAKKAPVKKAAVKKKATKKAAKKAAVKRKTTKKRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMG7</accession>
    <name>A0A518IMG7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_02240</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="67" mass="7176" checksum="5998A397D090B5B7" modified="2019-10-16" version="1">MVSLQGMIKYVYCSAAVPNVRGQLSSIIAQGLNNDGCVFAPILTFGRLCDHQFTGPGSRAEPVFNKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMI0</accession>
    <name>A0A518IMI0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF4065 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_02490</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025272">
        <property type="entry name" value="SocA_Panacea"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13274">
        <property type="entry name" value="DUF4065"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4065" evidence="1">
        <location>
            <begin position="31"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="192" mass="21316" checksum="EDA7665E8CBABBA7" modified="2019-10-16" version="1">MTPAEKSQRLIETASAALHAAPGHELNAVVLNKVLFYLDLATLRDQGEAVTGNSYIALRNGPVISKYPQRLIAKLESLGIARQDSRWDGAKPMVLEKCPTHFEYLSPDTMLLVSEVTDFFADSTSQAASDFSHKNPGWQIAWKHFRREGKPKAINLQIAMQQIVENDPWMETPLVDEAALLKAADDGLGDDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMN6</accession>
    <name>A0A518IMN6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_02970</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="135" mass="14539" checksum="CC1A596FAC19EF99" modified="2019-10-16" version="1">MPSSSPHTIRLRGPWKLTPLEIADAQPITGRIDQPSDQFLADYQGPILYVRHFNRPTGLGPAERVELAIIACVGTAHVSLNETPLANLTAQQAPVRIDITDQLQLSNQLAIEIIPPALPSPAGITGEVQLEIHSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMW7</accession>
    <name>A0A518IMW7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Outer membrane biogenesis protein BamB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_03940</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
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            <end position="24"/>
        </location>
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            <dbReference type="SAM" id="SignalP"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="QDV54440.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
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    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IN17</accession>
    <name>A0A518IN17_9BACT</name>
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        <recommendedName>
            <fullName evidence="2 7 8">Translation initiation factor IF-2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 11" type="primary">infB</name>
        <name evidence="11" type="ORF">Mal33_04340</name>
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        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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    </organism>
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mal33</strain>
        </source>
    </reference>
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        <text evidence="7 8">One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.</text>
    </comment>
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        <subcellularLocation>
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        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.</text>
    </comment>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7 8" id="KW-0648">Protein biosynthesis</keyword>
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            <end position="633"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
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        </location>
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        </location>
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        </location>
        <ligand>
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        </ligand>
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        <location>
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        </location>
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    </feature>
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    </evidence>
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    </evidence>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QDV54480.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="975" mass="104760" checksum="25F78EDF1AD2C9AC" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IN21</accession>
    <name>A0A518IN21_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Planctomycete cytochrome C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_04280</name>
    </gene>
    <organism evidence="5 6">
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        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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        <location>
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            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021739584" evidence="1">
        <location>
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            <end position="1042"/>
        </location>
    </feature>
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        <location>
            <begin position="45"/>
            <end position="105"/>
        </location>
    </feature>
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        <location>
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            <end position="356"/>
        </location>
    </feature>
    <feature type="domain" description="PSD1" evidence="3">
        <location>
            <begin position="735"/>
            <end position="986"/>
        </location>
    </feature>
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        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF07583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV54474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1042" mass="117124" checksum="116678B0D10F0E81" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IN33</accession>
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    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_04360</name>
    </gene>
    <organism evidence="2 3">
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        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1670.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023170">
        <property type="entry name" value="HhH_base_excis_C"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="SSF48150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="224"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="233"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="314"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="345" mass="36950" checksum="AEF825C22AB4006A" modified="2019-10-16" version="1">MSTTNRSARITKLFTLLKKRYKPLPPSAGRNLFEHFLYACLLEDGSQEAADEGIARLEQDYFDWNEVRVTTVSELAESFPRLPNATEAASRLKKNLHALFETYYSFDIEEMKKQNLGKTIKDLSEFPAMTSFVLAYIVQQGLGGHAIPINAVGMDLFYYCGIINDAERESDKVPGIERAIPKSKGTEFSSLLHQASLDFASNPQDPDLLKLILQINPDAMDLLPGKKAPAASPAKSKSSSKTASAKSAAGKAASTKSAAPKAAPVKKAAKKSTAPSPPDKAPLKGIAASIKAKKASASQPAKATPAKKGTAKSKTAKGAGDKSDADEATKPARSSTKKLAKKKPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IN94</accession>
    <name>A0A518IN94_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HTH-type transcriptional repressor NsrR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">nsrR</name>
        <name evidence="1" type="ORF">Mal33_05240</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030489">
        <property type="entry name" value="TR_Rrf2-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000944">
        <property type="entry name" value="Tscrpt_reg_Rrf2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33221">
        <property type="entry name" value="PTHR33221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02082">
        <property type="entry name" value="Rrf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00738">
        <property type="entry name" value="rrf2_super"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01332">
        <property type="entry name" value="HTH_RRF2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51197">
        <property type="entry name" value="HTH_RRF2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="139" mass="14949" checksum="552ECEE8F5652AC3" modified="2019-10-16" version="1">MKLTTQTDYALRTLMFLATRTSRANVADVASLFGISVNHVAKVVNLLARHGYIRSTRGIGGGIELALPPNEIGLGDVIQAIEGDLHLLACVGTDRGCAIDAFCKLKGVLAEAERVQRAYLDTVTLADVVPTRQQLECIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INJ9</accession>
    <name>A0A518INJ9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transposase DDE domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_06100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002559">
        <property type="entry name" value="Transposase_11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01609">
        <property type="entry name" value="DDE_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_1" evidence="2">
        <location>
            <begin position="165"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="423"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="440"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="460" mass="51308" checksum="09731F511491C077" modified="2019-10-16" version="1">MTVDELLDRFKNECPVAMGTRLMLNHLLSDERMDTLFATHAGSQRCGELLFSSVADIMACVALNIKPSVNAAYKKHKEKMKVSVTSVYNKLQGIETQVSRVLVSETAAELSQLWDHLEGPKPPPVLSGYKTRIIDGNHLAGTEHRIKELRTLGAAALPGTTIPILDPDKKLLVDVILSRDGHANEATLHPEILELVEKGEVWIGDRHFASQKMMTTIALDKKAFFVFRHSKGLLPNWESQGERRRIGRCDGGTIYEQKIAFTYQGRAICPRRVTIELDTPTRKGDTAVHVLTNLPSRVSAKSVANAYRKRWNIETAFQHLATTLNSEINTLGYPQAALFSFCMSMMMYNLISVMKTSIGCAAGDADLADEVSSYYAANDVSESWKGFMTAVTEKEFDSVYGKLTLKQLAKELVDVARKLDFSQYRKSHRGPKKPPPKRKSGNRGNHESTARILDQRAPKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INQ1</accession>
    <name>A0A518INQ1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Inositol 2-dehydrogenase</fullName>
            <ecNumber evidence="3">1.1.1.18</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">iolG_2</name>
        <name evidence="3" type="ORF">Mal33_06830</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.1.18" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050112">
        <property type="term" value="F:inositol 2-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043906">
        <property type="entry name" value="Gfo/Idh/MocA_OxRdtase_bact_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19051">
        <property type="entry name" value="GFO_IDH_MocA_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GFO_IDH_MocA" evidence="1">
        <location>
            <begin position="35"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="GFO_IDH_MocA_C2" evidence="2">
        <location>
            <begin position="196"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="426" mass="46555" checksum="D5AC03C44043E00E" modified="2019-10-16" version="1">MFDRRQFIASSVATTVAATAAHSKASAADANKPVKVGVMGLSRGMSLATDLAKMDGVEVKYICDVDSTRLASGAEKLGKIAGTSPEAITDFRKILDDKEVDALVCAAPNHWHGPATIMACKAGKHVYVEKPASHNAQEGEWMIEAAEKYNRVVQVGTQRRSAPEMIQAMEKLQSGAIGKVFLSRGYYVNQRGSIGKVEPSAPPENLDYALWEGPAPHREYKSNVVPYNWHWNWHWGGGELANNGVHTLDICRWGMGVDYPTRTTISGGRYCYDDDQITPDTQVVAFEFGDGSQITWQGTSCNKHNVNPFVSFYGTEGSMEVDSNGGFKLFNRANKMVEEVKGTNNGQLAHLTNFVDAVRSGDASTLNQPIAEGHCSTMMCHLGVIAYRTGQDVVSDPTNGHIQGPQEQKAMWGREYNPAWEADVSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INV2</accession>
    <name>A0A518INV2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_07380</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="251"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="256"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="367" mass="39661" checksum="A633D32E629EC373" modified="2019-10-16" version="1">MNGIDDSGWDHPADHRPRIRTGSRIMWCHWFVVGVLLLTSSLSGCASFQGVFSSCDCSINESLHLTRARMMARRVWSKEYASCYSQHCNTLAVRRGFIDGFVDVASGKDGCPPVFPPRNTNCFTGAFRSPDSACRDQAWFEGYPQGAAAAEQQGCHLWWRASVPAHLMAQYHHVDHLASTAACCGATEMAAESGQSEATAVLPAELVPEPQSQPASKRRAHNSVLESYSIEAASHETVSEVTPMLVREVQPPKHPAVSTPSVQQATSRKASSTTFRAAQPPVSRQNADRVAVYPVVVAVPPAMPAASAMPAASAAPTTAQRTSIQYHRNDGAQDSEGMILARTLEESPLSQVIRTSARWSEAANTSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INW4</accession>
    <name>A0A518INW4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_07420</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="74" mass="8464" checksum="C4D8E2FFC32149F1" modified="2019-10-16" version="1">MDKNTLKLFAPRRESLPSAPAVTVSVGDLVPLLVDAWETDRNWLRDFCKDEVSVSEDLYEVLLAYHQIRRCEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INY1</accession>
    <name>A0A518INY1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">SLBB domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_07220</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015159">
        <property type="term" value="F:polysaccharide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003715">
        <property type="entry name" value="Poly_export"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019554">
        <property type="entry name" value="Soluble_ligand-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02563">
        <property type="entry name" value="Poly_export"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10531">
        <property type="entry name" value="SLBB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021940077" evidence="2">
        <location>
            <begin position="27"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="domain" description="SLBB" evidence="3">
        <location>
            <begin position="142"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="SLBB" evidence="3">
        <location>
            <begin position="250"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF10531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV54762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="356" mass="38294" checksum="8F9BD80F2E563D7B" modified="2019-10-16" version="1" precursor="true">MKSLALFLSVWLGLAGLIGCSSTANYQASNLPQQLAAPKTVNAKKIDMTALAGTVQPADRLTPGDAVILTVATGIEQEKPPEWTLRVAEDGSLNVPLVGPVAVAGMRLTDAEKLLAFESVRRGVYVSPNVTLRIEQRRAHHVTVLGAVNKPQTYELPAGGSDLMTAISMAEGFSENANTIAQIRHPPGTGVRLAAMAQTQQVAYPNAPVPPPVPDQFELDLLRLDEVPENHRQLVDGSVVMIYEKPERYINVTGLVRQSDMIEMPKDGDMRLMDAISQAGGLSESLADKVKIIRKRPDDSEVVIEASIRDAMKGGPANLRLAPNDLVSVEETPLTYTLGTIKTFIRFGFSSAVPGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INY3</accession>
    <name>A0A518INY3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_07680</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006842">
        <property type="entry name" value="Transposase_31"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04754">
        <property type="entry name" value="Transposase_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transposase_31" evidence="1">
        <location>
            <begin position="9"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="321" mass="36572" checksum="777710BFC3FD13B5" modified="2019-10-16" version="1">MDDDESIHNPHDRFVRRLLGELDRVRDLVRWQLPAEVLAELDLESIRPAKESFVDIALREGLSDLVFDVKLSRGDDAFVVLLFEHKSTADPQTIFQVLRYIVGINDQRLRSGQPLCCVIPLVFYHGRSPWNVARTMQELVESPEPLRGFVPSFTMPLLDLSQCSDEELRGESVFLAYMALLKYIKRDELPERLPEILELFRKLLPPATALQSFETILRYIATGTDRVSKSELIAVVTQVLQVEGTSIMPTIAEQWKQEGRQEGERAGVKKGEQKGELIGRILVMEEVLKKPPTPKERLAGQDLQQLQSQVDALSAEMQSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INZ3</accession>
    <name>A0A518INZ3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="16">UvrABC system protein A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">uvrA_1</name>
        <name evidence="16" type="ORF">Mal33_07810</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009380">
        <property type="term" value="C:excinuclease repair complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004602">
        <property type="entry name" value="UvrA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041552">
        <property type="entry name" value="UvrA_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041102">
        <property type="entry name" value="UvrA_inter"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17755">
        <property type="entry name" value="UvrA_DNA-bind"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17760">
        <property type="entry name" value="UvrA_inter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00630">
        <property type="entry name" value="uvra"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6" id="KW-0228">DNA excision</keyword>
    <keyword evidence="12" id="KW-0234">DNA repair</keyword>
    <keyword evidence="11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10" id="KW-0267">Excision nuclease</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="ABC transporter" evidence="15">
        <location>
            <begin position="685"/>
            <end position="1016"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="15">
        <location>
            <begin position="1724"/>
            <end position="2064"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="248"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1423"/>
            <end position="1442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1662"/>
            <end position="1681"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1694"/>
            <end position="1727"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="254"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="1663"/>
            <end position="1679"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="1702"/>
            <end position="1727"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="720"/>
            <end position="727"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="1768"/>
            <end position="1775"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="QDV54816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="2459" mass="272113" checksum="67B485390AC10DA1" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP40</accession>
    <name>A0A518IP40_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_08240</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="97" mass="10288" checksum="A33919C4AE1ECF73" modified="2019-10-16" version="1">MSSLAIWEGGLIAEQIALEVSLAANRDWDSMNTLGRGGSLGDPHWDRLRSGSQSSNWPREVRSHAGVRRAVIGLFSGSCFPGLPCLCMACPSGGDSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPG3</accession>
    <name>A0A518IPG3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">Flagellar basal body rod protein FlgB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">flgB</name>
        <name evidence="8" type="ORF">Mal33_09510</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 5">Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Bacterial flagellum basal body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the flagella basal body rod proteins family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030694">
        <property type="term" value="C:bacterial-type flagellum basal body, rod"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001444">
        <property type="entry name" value="Flag_bb_rod_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006300">
        <property type="entry name" value="FlgB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30435:SF12">
        <property type="entry name" value="PTHR30435:SF12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00460">
        <property type="entry name" value="Flg_bb_rod"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002889">
        <property type="entry name" value="Rod_FlgB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="8" id="KW-0966">Cell projection</keyword>
    <keyword evidence="8" id="KW-0969">Cilium</keyword>
    <keyword evidence="8" id="KW-0282">Flagellum</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flg_bb_rod" evidence="7">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="58"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR002889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV54983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="134" mass="14844" checksum="BFD2BDCA480ED646" modified="2019-10-16" version="1">MLNIFNQTALPALEQSAIFAQRRHNVLAGNMANIDTPGYQARDLSTDEFQTALSEAIEATRNPSPGYSSGDAADIDPMDGPRRAMENLLYHDGSEINLERQVTEIAKNQNLHNTAIALMKNQFETLRVAISERV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPI1</accession>
    <name>A0A518IPI1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">Flagellar basal-body rod protein FlgC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">flgC</name>
        <name evidence="8" type="ORF">Mal33_09500</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="4 5">The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Bacterial flagellum basal body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the flagella basal body rod proteins family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030694">
        <property type="term" value="C:bacterial-type flagellum basal body, rod"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001444">
        <property type="entry name" value="Flag_bb_rod_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010930">
        <property type="entry name" value="Flg_bb/hook_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006299">
        <property type="entry name" value="FlgC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00460">
        <property type="entry name" value="Flg_bb_rod"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06429">
        <property type="entry name" value="Flg_bbr_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01395">
        <property type="entry name" value="FlgC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="8" id="KW-0966">Cell projection</keyword>
    <keyword evidence="8" id="KW-0969">Cilium</keyword>
    <keyword evidence="8" id="KW-0282">Flagellum</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flg_bb_rod" evidence="6">
        <location>
            <begin position="5"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="domain" description="Flg_bbr_C" evidence="7">
        <location>
            <begin position="93"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00025933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF06429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV54982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="140" mass="15188" checksum="76DB4BB640446B9B" modified="2019-10-16" version="1">MISALDISTSALVAQRVRLNTISGNIANMSSLKDENGNATPYKGRSVVFQTDDSVSTNPGVSGVKVDSIEISDAEPIYRYQPQHPLAIKEGKYQGYVAYPNIDMTTQMVDALEATRSYEANIGVMEITKNLGRESLSIIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPN4</accession>
    <name>A0A518IPN4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RNA polymerase sigma factor SigA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">sigA_3</name>
        <name evidence="5" type="synonym">sigA</name>
        <name evidence="9" type="ORF">Mal33_10160</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Interacts transiently with the RNA polymerase catalytic core.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the sigma-70 factor family. RpoD/SigA subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00963">
        <property type="entry name" value="Sigma70_RpoD_SigA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000943">
        <property type="entry name" value="RNA_pol_sigma70"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009042">
        <property type="entry name" value="RNA_pol_sigma70_r1_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007624">
        <property type="entry name" value="RNA_pol_sigma70_r3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007630">
        <property type="entry name" value="RNA_pol_sigma70_r4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028630">
        <property type="entry name" value="Sigma70_RpoD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00140">
        <property type="entry name" value="Sigma70_r1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04539">
        <property type="entry name" value="Sigma70_r3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04545">
        <property type="entry name" value="Sigma70_r4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00046">
        <property type="entry name" value="SIGMA70FCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00715">
        <property type="entry name" value="SIGMA70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00716">
        <property type="entry name" value="SIGMA70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="4 5" id="KW-0804">Transcription</keyword>
    <keyword evidence="1 5" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="RNA_pol_sigma70" evidence="7">
        <location>
            <begin position="309"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_sigma70" evidence="8">
        <location>
            <begin position="478"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="5">
        <location>
            <begin position="479"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Sigma-70 factor domain-2" evidence="5">
        <location>
            <begin position="285"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Sigma-70 factor domain-3" evidence="5">
        <location>
            <begin position="364"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="region of interest" description="Sigma-70 factor domain-4" evidence="5">
        <location>
            <begin position="453"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="209"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Interaction with polymerase core subunit RpoC" evidence="5">
        <location>
            <begin position="309"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS00716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV55048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="518" mass="60405" checksum="52ED6FCEF6B34E53" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPP7</accession>
    <name>A0A518IPP7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DinB superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_10210</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024775">
        <property type="entry name" value="DinB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12867">
        <property type="entry name" value="DinB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DinB_2" evidence="1">
        <location>
            <begin position="20"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="176" mass="19905" checksum="34DF0B81FC459F38" modified="2019-10-16" version="1">MSVELDIETVEKSRAVALGQIEFARQYTLELLDNTPQELWFQMPAGLPTHVAWQVGHLAYSQYGLLVFRQRGREPEDLELVPGTFRKKYGRGTTPDADPAGQPTPDELLQRLSTIHQRSIEVVTESSPQRLLEPIDMPYAVYPNKLGAILFCPLHEHIHAGQIGLLRRMLGLNPVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPS9</accession>
    <name>A0A518IPS9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_10750</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="164" mass="18890" checksum="E9BCF6F4BE6616A3" modified="2019-10-16" version="1">MLSEYKVSRCSRRCSVLDRPLKPGETFYSVVFEDDEDFARKDISAEAWEGPPEEAIGWWQGKMPEAGAGRMKLAPNHVLLDLLKQMSEQPHREAVRYLLALMLMRKRVVRPLDHEEGAVDGMLVVQVLADNSQIEVAECEIPREERDQIRDELTELLYCEVEES</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPU7</accession>
    <name>A0A518IPU7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_10880</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="132" mass="14948" checksum="55C9B70091CF66A4" modified="2019-10-16" version="1">MSQFSDSPLLQKTREFVERVVNKGEFVEVMQDYFDDNEYVQIEGDGRTLNSKQEIIDFEVDALKSVTKYHGGTIGAIGVAQDDGNGNGVTMAEYSFSYDTTDGKTVVLEETQIAKWKNGKMVYNRYYFNPNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQE9</accession>
    <name>A0A518IQE9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Flagellar basal-body rod protein FlgG</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Distal rod protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">flgG_2</name>
        <name evidence="8" type="ORF">Mal33_12920</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Bacterial flagellum basal body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the flagella basal body rod proteins family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009426">
        <property type="term" value="C:bacterial-type flagellum basal body, distal rod"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001444">
        <property type="entry name" value="Flag_bb_rod_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019776">
        <property type="entry name" value="Flagellar_basal_body_rod_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020013">
        <property type="entry name" value="Flagellar_FlgE/F/G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010930">
        <property type="entry name" value="Flg_bb/hook_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037925">
        <property type="entry name" value="FlgE/F/G-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012834">
        <property type="entry name" value="FlgG_G_neg"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00460">
        <property type="entry name" value="Flg_bb_rod"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06429">
        <property type="entry name" value="Flg_bbr_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117143">
        <property type="entry name" value="SSF117143"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03506">
        <property type="entry name" value="FlgEFG_subfam"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02488">
        <property type="entry name" value="flgG_G_neg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00588">
        <property type="entry name" value="FLAGELLA_BB_ROD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="8" id="KW-0966">Cell projection</keyword>
    <keyword evidence="8" id="KW-0969">Cilium</keyword>
    <keyword evidence="8" id="KW-0282">Flagellum</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flg_bb_rod" evidence="6">
        <location>
            <begin position="6"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="domain" description="Flg_bbr_C" evidence="7">
        <location>
            <begin position="188"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00032912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF06429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV55321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="268" mass="29048" checksum="98C6F18CF8C12847" modified="2019-10-16" version="1">MSVQTLYTAATGMDAMETKLDVIANNLANVNTTGFKRDRANFEDLLYRNEIYPGVQDSNQTPTPTGTQIGLGVRVMSTQTDHSQGTLEQTGRELDFGIEGRGFLPVLDPRSQTTVYTRAANLDVNANGQLVLGSAQTGRLIDPPITIPQDATQIQISDTGIVSVRIPGTVELQQQGQIQLAQFVNPDGLLKIGENLYQETEASGTNQLSDPGSDGAGVIRQGNLEVSNVEPVRELIDLITTQRAFELNSQAVQAGDQMMQTIANLRRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQL0</accession>
    <name>A0A518IQL0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_13470</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_009096979.1">
        <property type="nucleotide sequence ID" value="NZ_CP036318.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021817998" evidence="1">
        <location>
            <begin position="26"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="121" mass="12925" checksum="A0FC647E12F0ED64" modified="2019-10-16" version="1" precursor="true">MNRAFAIAALAAGLFAFAGNTGATASDYFHGGHGGHHAYSGGHHGGGHHGGYAQAPVQTYGNYGYSSNYGGYGYGQTYQPSYQPQYQQQYSPTYRSQPYRQRGGLHLDIGRFHVLGAGGHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQL4</accession>
    <name>A0A518IQL4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF305 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_13620</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005183">
        <property type="entry name" value="DUF305"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03713">
        <property type="entry name" value="DUF305"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="39"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="67"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="DUF305" evidence="3">
        <location>
            <begin position="93"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="129"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV55391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="158" mass="17988" checksum="33D4C9366BD3B8EA" modified="2019-10-16" version="1">MSNYRLFGAMIATSTAVMLLLMYLNTYAIDHVYWSETRFYMALVMGATMAMIMLSFMLGMYKNMKTNVAIFATSVAVFAGSLYLVRSQETVEDVSWMKAMIPHHSIAILTSERAEITDPRVRELADQIIETQKKEIAEMKRLIADLEDEETNALALEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQX5</accession>
    <name>A0A518IQX5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_14270</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025591">
        <property type="entry name" value="RloB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13707">
        <property type="entry name" value="RloB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="213" mass="24006" checksum="E70E45FE3AA9D0D6" modified="2019-10-16" version="1">MGRRDRPRKPARRPAFRESLPRILIVTEGAETERAYFEGLARSEKNPLVTVDVIGGAGVPRSIVQRAKELKNEASKRARREQDDNLQYNEVWCAFDVDEHPGIEAAVQMAGANEIQVAISNPCIELWLWLHFADQPGMQGRHKLLKMLKSHLPNYNKSIDFDIYKPHVPKACARAAKLDQLHESTNSPGANPSTGVWRLVRVIQKGPQSDGQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQY3</accession>
    <name>A0A518IQY3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_14370</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="136" mass="14833" checksum="B0CA235F23A31618" modified="2019-10-16" version="1">MTPTDFTDVILGLLHRFEAASIKTPAAVVDESPLQAIGKSARETLTVLAFITVRLFERISLSFPPGIENFLAPTDIIPIRRVVKTTTPPSSRRIGRSADSDRVAPGNCCANGRPWNVSPIKRAILARSLRHLMSVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRD8</accession>
    <name>A0A518IRD8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_16280</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="195" mass="20853" checksum="30DA2676EE97A007" modified="2019-10-16" version="1">MVRPRDEFIRTEDQRSGNLHSPGHRPGGQASHANSPEQRTKGSAVCIAQANGLGSGCPARIPPPESRTEGPVVCIAQAIGLGGGGVRHESPPPESRAEGPVVCPTLLNCRAFSPNRFALRSDYPGRWPGLCKLPSLRPWGHVAGPSALTFCVAIQRPRPMAWAMQIAGPSVLGHKWRTFVPVQTNCRDGEPAYAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRQ3</accession>
    <name>A0A518IRQ3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Isochorismatase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_17550</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000868">
        <property type="entry name" value="Isochorismatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00857">
        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="SSF52499"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isochorismatase" evidence="1">
        <location>
            <begin position="17"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="188" mass="20579" checksum="D5F4353369EF2EF3" modified="2019-10-16" version="1">MDPTFRSSRLIDRARSGLLVVDLQTKLLPGIDQSEQIVANTDRLCRAAELLNVPQTASVQYPQGLGPLEARLAERFPTPDEKLDFSAAGCASIAQLAETHNLTQWIVVGIETHICVLQTTLDLLARQLDVFVVADAVGARGDRDHRIGLDRMQAEGATLVTTESVLFEWCQTAADPKFKQISAIVREG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRW8</accession>
    <name>A0A518IRW8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sodium/pantothenate symporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">panF_1</name>
        <name evidence="8" type="ORF">Mal33_18030</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1730.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038377">
        <property type="entry name" value="Na/Glc_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001734">
        <property type="entry name" value="Na/solute_symporter"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00474">
        <property type="entry name" value="SSF"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50283">
        <property type="entry name" value="NA_SOLUT_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </evidence>
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    </evidence>
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        <source>
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    <sequence length="660" mass="70961" checksum="73FE09E1728D7B2F" modified="2019-10-16" version="1"> </sequence>
</entry>
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
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                <person name="Overmann J."/>
                <person name="Amann R."/>
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                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
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        <reaction evidence="3">
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        </reaction>
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</entry>
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    <accession>A0A518IS46</accession>
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        <submittedName>
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                <person name="Pinto D."/>
                <person name="Vollmers J."/>
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                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
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                <person name="Luecker S."/>
                <person name="Lage O.M."/>
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                <person name="Merkel B.J."/>
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                <person name="Overmann J."/>
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                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">Mal33</strain>
        </source>
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    <dbReference type="EMBL" id="CP036318">
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        <property type="project" value="InterPro"/>
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        <property type="match status" value="1"/>
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        <source>
            <dbReference type="EMBL" id="QDV55917.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
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    </evidence>
    <sequence length="385" mass="40186" checksum="FEC47AE83F5A7251" modified="2019-10-16" version="1">MNLLLLVGILLVAVNLRPALASVGPLVEEIRQSTSLSSSQLGLLTTLPLIAFGVISTLTPLFTRRLGIGGTLLGALALLAFGIAIRYVAWLPALYLGTLCLGIAIAFGNVLLPSITKRNFAANSGFVTSLYSSGMALGASMAAGLSIPLANGVGLGWRGALGIWAIPAAIAFVAWLPQVRRLTRSEPNRSFAKAMKDLGGSRLAWQVAFFMGLQSLTYYAVLAWLPAILISRGYDASFSGWMLSLSQGMGIVGSLIIPTIAGRKPDQRGIIWFLASVEAVGLVGLIASPAGWIAIWVSLIGLVLGGSFGLALLFIVLRTRHPETATELSGMAQSIGYLIAGTGPLLFGSLFDLTGAWTCSILFLMAVAVLKLAMGLGAAAARTVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IS72</accession>
    <name>A0A518IS72_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Trehalose utilization</fullName>
        </submittedName>
    </protein>
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    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetia</taxon>
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    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
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                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
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                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
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    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
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        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
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        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
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        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="FA58C"/>
    </dbReference>
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        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
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        <property type="entry name" value="Haem-bd_dom_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011041">
        <property type="entry name" value="Quinoprot_gluc/sorb_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029010">
        <property type="entry name" value="ThuA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00034">
        <property type="entry name" value="Cytochrom_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00754">
        <property type="entry name" value="F5_F8_type_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06283">
        <property type="entry name" value="ThuA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="CxxCH_TIGR02603"/>
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    </dbReference>
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        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="FA58C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F5/8 type C" evidence="5">
        <location>
            <begin position="322"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="6">
        <location>
            <begin position="1303"/>
            <end position="1438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV55947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1439" mass="156479" checksum="F67447E85DB026E8" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISA8</accession>
    <name>A0A518ISA8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphoribosylglycinamide formyltransferase</fullName>
            <ecNumber evidence="3">2.1.2.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">purN</name>
        <name evidence="3" type="ORF">Mal33_19510</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.1.2.2" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="F:phosphoribosylglycinamide formyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08645">
        <property type="entry name" value="FMT_core_GART"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Formyl_transf_N"/>
    </dbReference>
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        <property type="entry name" value="Formyl_transf_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004607">
        <property type="entry name" value="GART"/>
    </dbReference>
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        <property type="entry name" value="Formyl_trans_N"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF53328"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00639">
        <property type="entry name" value="PurN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Formyl_trans_N" evidence="2">
        <location>
            <begin position="5"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="210" mass="22705" checksum="B7ABDB2D7A3CC344" modified="2019-10-16" version="1">MSLPIAVFISGGGTTLRNLIAWQQRGQLDVDFRLVISSAANAKGLEFAAGESIPHQVITKTQFADDKAYSEAMFQPCRDAGVELVVMAGFLKHVLIPTDFENRVVNIHPSLIPSFCGAGMYGSRVHQAVLDFGAKLSGCTVHFVDNDFDHGPIIAQHACEVRGDDTAASLAARVFERECDALPRVVQAIAEGRVSVTGRRVHTQPTERSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISF6</accession>
    <name>A0A518ISF6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_20150</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="114" mass="12657" checksum="C3117F8202370E5A" modified="2019-10-16" version="1">MSEEAAARPGNLLANLPQNVPEELTEILASGSGLRVERIVSTGHRSPDGFWYDQPEREWVLLLQGAATLQFADPPESIDLIPGDHVDIVAHRRHRVESTSATEPTVWLAVFYQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISM5</accession>
    <name>A0A518ISM5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Outer membrane efflux protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_20760</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="320"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="584" mass="63979" checksum="B56F2677AEAF9382" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISN8</accession>
    <name>A0A518ISN8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cyclic di-GMP phosphodiesterase response regulator RpfG</fullName>
            <ecNumber evidence="6">3.1.4.52</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rpfG_2</name>
        <name evidence="6" type="ORF">Mal33_20780</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.4.52" evidence="6"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071111">
        <property type="term" value="F:cyclic-guanylate-specific phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037522">
        <property type="entry name" value="HD_GYP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006675">
        <property type="entry name" value="HDIG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00277">
        <property type="entry name" value="HDIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51831">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51832">
        <property type="entry name" value="HD_GYP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="146"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="2">
        <location>
            <begin position="254"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="3">
        <location>
            <begin position="360"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="domain" description="HD-GYP" evidence="5">
        <location>
            <begin position="514"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="domain" description="HD" evidence="4">
        <location>
            <begin position="536"/>
            <end position="658"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV56099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="813" mass="89514" checksum="71939ACAD7A1366A" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISV7</accession>
    <name>A0A518ISV7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative glycosyl transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_21220</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13579">
        <property type="entry name" value="Glyco_trans_4_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="3">
        <location>
            <begin position="25"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="2">
        <location>
            <begin position="223"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="408"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="409"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV56143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="427" mass="47719" checksum="A600C765CBAFEE64" modified="2019-10-16" version="1">MTSPKIAFLNRCYWPDVEATGQLLEQLCGALSSDWDITVVAGQPNKNLTGQEFVRRGQQKRDGVTIDRLPHTTLPKRSKVGRLINLLSFTWQTRRWGRRVPAAQSFDVIVSESDPFFLPIVAAPIARRMGAKFVVYTQDVYPDIAIGLGVIKEGTITRQIRQRLLAAYRQADRIVVLDDDMRDRLVGWGLPPEKFSIVPNWVDTEAIRPLEGTNPFRVAQDLDDRFVVMHSGNMGMSQRLEVLIDAACHPDWPEQAVVALVGDGARKSALQAYAAQKGAKHVRFIEYQPIERLTESLSAADLHVVSMDANIRGCLAPSKLYGILASGTPVMAITPDTFSIAREIQSHQVGRAVEPGSISQIVDYVRWCIKHPRELEASGENARRLAQAKYDRKISCQQFADVLNSVCDREHSDQQPSSTPETYSETQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITA8</accession>
    <name>A0A518ITA8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Acetylornithine aminotransferase</fullName>
            <shortName evidence="2">ACOAT</shortName>
            <ecNumber evidence="2">2.6.1.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">argD_1</name>
        <name evidence="2" type="synonym">argD</name>
        <name evidence="4" type="ORF">Mal33_23070</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>2-oxoglutarate + N(2)-acetyl-L-ornithine = L-glutamate + N-acetyl-L-glutamate 5-semialdehyde</text>
            <dbReference type="Rhea" id="RHEA:18049"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29123"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57805"/>
            <dbReference type="EC" id="2.6.1.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
        <text evidence="2">Binds 1 pyridoxal phosphate per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 4/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="2">May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.11" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00109"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003992">
        <property type="term" value="F:N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01107">
        <property type="entry name" value="ArgD_aminotrans_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004636">
        <property type="entry name" value="AcOrn/SuccOrn_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000521">
        <property type="entry name" value="Transaminase_4ab_Lys_Orn"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00707">
        <property type="entry name" value="argD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2 4" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="2" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="2">
        <location>
            <begin position="109"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="2">
        <location>
            <begin position="223"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="138"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>N(2)-acetyl-L-ornithine</name>
            <dbReference type="ChEBI" id="CHEBI:57805"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="280"/>
        </location>
        <ligand>
            <name>N(2)-acetyl-L-ornithine</name>
            <dbReference type="ChEBI" id="CHEBI:57805"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="281"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="2">
        <location>
            <position position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV56325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="403" mass="43422" checksum="98482D2B10A2D308" modified="2019-10-16" version="1">MSDYLSSSDTVELFDQYVIPNYVRYPVNLVRGEGAKVWDSEGKEYLDLFPGWGCNLLGHCPPRIVEAVQKQVAELIHVPNTWYMQQQGQWAQMLSERSFGGQAFFCNSGAEANEAAIKLARLHTPAERYKIITFTGGFHGRTLGALTATAQPKYHEGLGPLVAGFTYCPFGDLAAVREAVGDQTCAIMLEPIQGEGGVQLPPDGFLQGLRELADEHGLVLIFDEVQTGCGRTGEWFGHQYFGVEPDIMTLAKSLCGGIAGGAMMARPEIAASLKPGTHASTFGGNPIAAAAGIAAIETIEAEGLLDHAKQLSQLIEEKANALVDQFEFVRQVRVAGLMIGIELDIEGAPIVAQCMKQGLLINCTQGNILRLLPAMNLELSDAERGLDMIAEALQAVGRESIEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITG3</accession>
    <name>A0A518ITG3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">MPN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Mal33_23680</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the UPF0758 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08071">
        <property type="entry name" value="MPN_DUF2466"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025657">
        <property type="entry name" value="RadC_JAB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001405">
        <property type="entry name" value="UPF0758"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020891">
        <property type="entry name" value="UPF0758_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30471">
        <property type="entry name" value="PTHR30471"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04002">
        <property type="entry name" value="RadC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00608">
        <property type="entry name" value="radc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01302">
        <property type="entry name" value="UPF0758"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="MPN" evidence="7">
        <location>
            <begin position="200"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV56379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="324" mass="35771" checksum="B0FDED0CD4806729" modified="2019-10-16" version="1">MTAAKQPTDSATRRYQRYLPVIESVSARDGFPIDVVHRACDPEKRGFVTRVVNELVGQGWLLRESKTADQTLYRWNTGLGEFSPTRWLDEKLFGNQVKLAPQEDRPRERLLAWGAESLRTAELLAILVRSGRPGESAMMAGEHLANEFAGKLDRLPTAGRGELKSISPAVEKTAYCQIMAGIELGRRIAALAGPPKTSKICSTAEAAEFCRRHFARLVSDQRREEFHIVTLDTKNQVIDTHCITVGTLDASLVHPREVFRAAIKDAAQSIVLVHNHPSGDPTPSPEDFAVTRRLESAGDTIGIGVLDHIVLGRQGHVSIRQAEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITK2</accession>
    <name>A0A518ITK2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">23S rRNA (Guanine(745)-N(1))-methyltransferase</fullName>
            <ecNumber evidence="4">2.1.1.187</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rlmA</name>
        <name evidence="4" type="ORF">Mal33_24090</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.1.1.187" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052911">
        <property type="term" value="F:23S rRNA (guanine(745)-N(1))-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016718">
        <property type="entry name" value="rRNA_m1G-MeTrfase_A_prd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018249">
        <property type="entry name" value="MyrA_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Methyltransf_25" evidence="3">
        <location>
            <begin position="93"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="2">
        <location>
            <begin position="99"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="24"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="28"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR018249-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR018249-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV56419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="274" mass="30806" checksum="3C6D9210267E2E66" modified="2019-10-16" version="1">MFQLRCTVRDCQELLEPCERGLACRAGHHFDQAKQGYWNLLQPQDKKSKNPGDSLDAVLARHRWLQRGHATSLIETLRPWVATADAQTNQRTLDLGCGEGSFGPALFPDDADSYCGIDLSRRAIKLAARRWPEATWVLANADRELPAADQSVQRVISLFGRRPVSEIYRVLAPGGICVVAVPGEDDLIELREKVQQAGHRRSRWEMIADEMTDAGLEVVDRKHWHINVNLDPDAIADALAMTYRAVRHSQKSRLDVVQAMDVTLAADLLLLRRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITQ0</accession>
    <name>A0A518ITQ0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Inosine-uridine preferring nucleoside hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_24480</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016799">
        <property type="term" value="F:hydrolase activity, hydrolyzing N-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.245.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001910">
        <property type="entry name" value="Inosine/uridine_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036452">
        <property type="entry name" value="Ribo_hydro-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01156">
        <property type="entry name" value="IU_nuc_hydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53590">
        <property type="entry name" value="SSF53590"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021717473" evidence="1">
        <location>
            <begin position="22"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="domain" description="IU_nuc_hydro" evidence="2">
        <location>
            <begin position="34"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="345" mass="38258" checksum="7FEFE764C71367D4" modified="2019-10-16" version="1" precursor="true">MNLRSLLTLCIVVAVLPTAQADQPEESFKRPVRVIFDTDITGDVDDVLALAMLHTLADRGECVIEAVTVSKINPLAAPFVDAVNTFYGRPDIPIGATRDAQKRDSKYLSLVKTRDGDQFRYPHDLLSSDDAPTAVEVLRKTLAAAEDSSITLVQVGLASNLADLIESPADAISSLTGTELVRKKVRLVSLMAGAFVPVNGNKRFLEANVRNGIGAMQRFVDGWPDDVPAIWSGYPIGVATAFPRESIAREFEYRKHHIVKEAYLMYCGPDHDRPSWDLTSVLYAVRPEDNFFGLSPRGRVVVEDDGFTRFEPSENGRDRYMTLSPKQRIRVIEAQRCLVSQPPLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITT0</accession>
    <name>A0A518ITT0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_24860</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="204" mass="22814" checksum="805AE340CC82B312" modified="2019-10-16" version="1">MLGTCRVAGFGVCLILLCLVGCNGSLESVPATQPVPPPAAEIPVANLPVDLREWNWTNRLGIGSCAHASFVYHLRWQNQLELAERWRATHSGGESATSMQRAVRAEGLPFNATTTADPAFLDWASRTRRGAIIWFFKDHAVHFCGWATVDGIEYAILCDNNRIERYLRVERSEFLRRWKQYDGFALSTTFSPVPPALFPAFESV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IU13</accession>
    <name>A0A518IU13_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_25650</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="120"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="147"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="171"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="198"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="224"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="256"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="306" mass="31974" checksum="9FDFCA180339789F" modified="2019-10-16" version="1">MFSIQDILYGGCLPAVVAVFVFVVVSRVLPERVGSRYASAAALTLGFFAGYAMLALGPWAAESHWHWLPYAVLIASVAGPIAAAEGVHAVERWLMFALLGGVAAWFLVPDWDDLQPSWAVHASVLAIYIACLAGGLESLARRIPGPLLPATLWMTLSAAAVVLALSGSLRFAQIALAGAAAMFGLAILAWFRPTKTSLVGCGFAVAVLVAGALLIGRVNSFSEVPLATYLLIPLAPLALFASLAGPLSRSEGFKGVVVRLALPILLLGIAVGLAIAAEAGSEEMDYSMRQLPQRLNASPSQLDALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IU69</accession>
    <name>A0A518IU69_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_26200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="321" mass="35597" checksum="BE6B7A03A5A5D827" modified="2019-10-16" version="1">MTKPNPARINFTTLFAVLALAAVAVYCLPIALSQAPSESGPTSKSPTEPAESGVSSSNATKAWQTLNGAIRQLVDTGPAFEAKLRQVTRVDGQEVRAVGRYIQSSGLRGLMRMELQSPIGNQTSRFEQTCDGRLTWTREQVGEEVRIRRVDVGRLDEIAFTSGVSARFKVGGLPELLDSIAWDYDLQLVRGVLKETQNVWIIRGTLKESRLQSLLDENEQTIVPPELPTKVRVALAADGPFRLIPVRMEFSSEPPEGGSGPARLISELDIYEIKAIDPPKEELFRYSTTEDDAHFTNETQIYLDRFQTRMATLPGFSGMRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IU74</accession>
    <name>A0A518IU74_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_26240</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="342"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="397" mass="44388" checksum="F8361E9CFC527D3D" modified="2019-10-16" version="1">MSPLDANGISEIEIDTMELHRCLFNLLSFNGNWTREPKATVEALQELHGYYVGLKLRETNRDYFATGSPVCIDGRTESSLHRWLVAAAGRLLQRCCGLVGGDFFILSSRDAGEYLSRIAEFGDGVELDSAISGSLSQRDLLDMEGLLAFEYEHACRIWPTPPDALGPWAKLAKAFRDQARRDDDSFIAIRFSEGDRIDRKVTSNGWLVTYPYDSEDNETRVKLIGLSRAAAKLLGATVIEDTPDEWAGVWFDYVVCRAESGWTTRHEVYSVGGQGSTFDSTNGTETGMISRPFYWSAVACDELQFDAPVSGHNEMDSRPQESVPDYVTLKQAAPLVGRSKGTLENWKRDDPEFPPPDVIGGDGRANEWRWSNLRPYLQTRTKRELPEVHPATQGVGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUI0</accession>
    <name>A0A518IUI0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">3-oxoacyl-[acyl-carrier-protein] reductase FabG</fullName>
            <ecNumber evidence="1">1.1.1.100</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">fabG_3</name>
        <name evidence="1" type="ORF">Mal33_27400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.1.100" evidence="1"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004316">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="250" mass="26102" checksum="F08BB86A0F30AB8D" modified="2019-10-16" version="1">MISIDLTQKTAVVTGGGQGLGLQTATTLHAAGANVVLTYFQDAAGVNQQRAEQAASGLGSRAKAVEGDVRDRDSIAAMFDAVVGHFGSLDIVVNNAAILRDRTLKKMSDDEWGSVIDTNLSGVYRVCKEASERIADGGRIVNMTSISGFTGFFGQANYSAAKAGVVGLTKAISKELASRRITVNAVAPGVVLTEMGASIPEAARAEMLKQIPLGRFGEPAEIANAILFLCSPLADYMTGQTLHVNGGWLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUJ6</accession>
    <name>A0A518IUJ6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_27450</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="175" mass="18849" checksum="724446AD5D2804EE" modified="2019-10-16" version="1">MGLADWWYVFQTTRLSKPAEDRVLFRATANRKIQSVLETGLGDGTRCDRLLQWLQHHDSVPMRYAAIDQFEAGGGLSLKQFHAKMTGMGIKPMPVPGTLATGLPRVAHTIGAVDLVILDQDHEGLSDPSILNFLPRIVHAETVVIATDAETGALYSVDASELIDGTASSPAQAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUY6</accession>
    <name>A0A518IUY6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_28980</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="98" mass="11065" checksum="BC8D3034310266A0" modified="2019-10-16" version="1">MDTLRVLSSLSELPADEVDYQVYENLDADVRAALCMDNLREIAQAELLSPKVVAEIEFIRDATVLLIDRRIPGADLTEHDEWRHVISRAKTALDSISK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IV08</accession>
    <name>A0A518IV08_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_29220</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="143" mass="15949" checksum="17808638991EFCBF" modified="2019-10-16" version="1">MATQQLITPHFLDPSFVDGSATPNGETEIQQRVQRYLMRAGLAEPHARQAADQITSDVSGQPCDDDPTVRQRQAISLAIAHVQAQSDGDQRLPNRSVPTESWQAMVKASDAHRRRRHRRTRLLISLGQSLLRLPKPNPAVRTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IV42</accession>
    <name>A0A518IV42_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Low molecular weight protein-tyrosine-phosphatase YwlE</fullName>
            <ecNumber evidence="4">3.1.3.48</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ywlE</name>
        <name evidence="4" type="ORF">Mal33_29410</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the low molecular weight phosphotyrosine protein phosphatase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.48" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003725">
        <property type="term" value="F:double-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006470">
        <property type="term" value="P:protein dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017945">
        <property type="entry name" value="DHBP_synth_RibB-like_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023485">
        <property type="entry name" value="Ptyr_pPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036196">
        <property type="entry name" value="Ptyr_pPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017867">
        <property type="entry name" value="Tyr_phospatase_low_mol_wt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006070">
        <property type="entry name" value="YrdC-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01451">
        <property type="entry name" value="LMWPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01300">
        <property type="entry name" value="Sua5_yciO_yrdC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00719">
        <property type="entry name" value="LMWPTPASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00226">
        <property type="entry name" value="LMWPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52788">
        <property type="entry name" value="SSF52788"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55821">
        <property type="entry name" value="SSF55821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51163">
        <property type="entry name" value="YRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YrdC-like" evidence="3">
        <location>
            <begin position="14"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV56940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="397" mass="42958" checksum="B7D55F077062E160" modified="2019-10-16" version="1">MPTVIDLQRAEDPRDIVYLAVQALAEGKVIALPTETVYGLAASVLCADAVQRMTELKRKLEEQTPTGGKPRTEYSLAIAVKSADEAIDYMCHDSPLAIRFARRCWPGPVTLVVPCDPTRSAASCFPEAVRELVVSQSGHIGVRVVAHRLFEQLQKYCAGPIVICSANRCGSPSTTTGVAVVEQFGDDVPLVVDDGPTRYGGPSTVVRANGNQFKIIREGVVETAAIRQYARPSIVLVCTGNTCRSPMAEALLKKRIDERFGNSPSGAIIPSVSSVGLAAMPGDQAATQAVDVMRERGLDISGHESQPFGEQTIRSADLILTMTRSHRNAILQRWPHAQDRVFTVRRDGGDISDPVGSPVQIYQACADQIDRELAQWVESLGPEWLAIPESGEEGENQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IV43</accession>
    <name>A0A518IV43_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Undecaprenyl-phosphate mannosyltransferase</fullName>
            <ecNumber evidence="2">2.4.1.54</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_29650</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.4.1.54" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004582">
        <property type="term" value="F:dolichyl-phosphate beta-D-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047267">
        <property type="term" value="F:undecaprenyl-phosphate mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd06442">
        <property type="entry name" value="DPM1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039528">
        <property type="entry name" value="DPM1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43398">
        <property type="entry name" value="PTHR43398"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="20"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="251" mass="27132" checksum="4F2374D626F2BD5B" modified="2019-10-16" version="1">MIDSPDKDEHGGAPVARVLVAVCTYNELDSLPELVAGIRAALPSADVLVVDDGSPDGTGEWAADKAGRDPWFTVIQRGRKLGLGSAIVAAMRHASDAGYDFLVNLDGDMSHDPVEIPKLVDVAHREQADVVIGSRYVPGGAIEGWPMSRLVISGLLNRVARIALGLQAHDCSGAYRCYRVDTLDKVDLNRIRASGYAMLEEILWLLTHRDAKIVEIPIRFVNRVQGSSKLSLGEAVKSIAMLARIACSPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IV51</accession>
    <name>A0A518IV51_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Serine dehydrogenase proteinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_29680</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002825">
        <property type="entry name" value="Pept_S49_ser-pept_pro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01972">
        <property type="entry name" value="SDH_sah"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="287"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="317"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="342"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="366"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="404"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="522" mass="56089" checksum="487860F9AA883478" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVC2</accession>
    <name>A0A518IVC2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_30350</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="293"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="220"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="53"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="97"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="403" mass="42458" checksum="D834CF89CEEEBFA4" modified="2019-10-16" version="1">MLSANPLTLASDDLGYRGGEGDGFSDTQIVAGGSRGGGPRDAAAQQGNDRGGPESRDSGDREESRLGRLDDQRPGGERRGGDRNGDRPPLRRDRGSSDGTPTITDNDQSSTTLPDVVNVTIRNETTTTSIGDSTSPIRTPVVSSSGPGVDSNPAVPGLSGEQGDLGPMQADVDGVSETVLVSVTPQGELWELSPESFDQVLRAESETFANPSTVEAIEAVDQWLNQSDAFRDQIEQLDQAIEDLAEEDPAAEPEAFELHEGTELQPDTAAEAVPSESNSQQWLLETSGLLLENDSSSRTVADPQSPRSGESIANAGWNVGIGVFKAFESVLPAAPQRSLSAALLPTVATPPRIPSPVEPTAESDSQRSLAWYEGASLAVITIAGVVYVRRSRAEAVRNPADFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVI5</accession>
    <name>A0A518IVI5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">1,5-anhydro-D-fructose reductase</fullName>
            <ecNumber evidence="3">1.1.1.292</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">afr_5</name>
        <name evidence="3" type="ORF">Mal33_31020</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.1.292" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033712">
        <property type="term" value="F:1,5-anhydro-D-fructose reductase (1,5-anhydro-D-mannitol-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004104">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02894">
        <property type="entry name" value="GFO_IDH_MocA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GFO_IDH_MocA" evidence="1">
        <location>
            <begin position="4"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="GFO_IDH_MocA_C" evidence="2">
        <location>
            <begin position="142"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="376" mass="42030" checksum="88F4BD291818E808" modified="2019-10-16" version="1">MKNVNIGMIGYGFMGKAHTNGYAQANHFFKLGHKPVLKALCARNAEKAQEFADNWGYESIETDWRELLKRDDIDAVDICVPNNLHKEISIAAAEAGKAVLCEKPLAIDVAEGEAMCEAVEKAGVPNMVWYNYRRVPAVSLAKQIIDEGRLGKIFHYRANFLQDWTINADVPQGGAATWRLDAEAAGSGVTGDLLAHCIDTAIWLNGNIKDVSAMTETFVKERMHAETGKKEPVTIDDACMFHCHFENGSLGLFESTRYARGHKALNTLEINGEHGSLAWDLHDLHRLQYFNYADDGIVRGWRDVHVSDGDQPYMGNWWVPGLNIGYEHSFIHQVADFLKSLDEGKPVHPSFRDALETQKVCDAVLKSAKERAWMDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVR9</accession>
    <name>A0A518IVR9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_31780</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="383" mass="43131" checksum="F23EAD5885CB742A" modified="2019-10-16" version="1">MSTTSDTFDQLIACREDPASVLSRLVDHYRTQRLPHELFETLKLQTRLKLGLPLFSTDDDPPAGEELDRQMEMGLIDACREVGQMLMQEGRIAEGWMYLRPVGNLPLVAEMMRDIQPNEENTDDLVQVLLHEGVDIARGYQLILENNGTCNSITTYEQSIIGRPPAAQRPAASLLLDHVYNELVESVRGDIEQREGAPPESNNIVELIADRGWLFSDNGYHIDTTHLASTIRFARVLDDPAQIRRAWEMTQYGRKLNRQFQYPGDEPFADFYSSHDLYFSVLLGEKVDEGIAYFERKVRNVDMLEKGTGPIETYVELLDRVGRPAEALAAAVEYTPAEVPATRVVPLMLELAKKGAGYEPIQDFCKARGDLLGYAAALITPKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVT0</accession>
    <name>A0A518IVT0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_31950</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="24"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="253" mass="26822" checksum="432CCAB4C72E27C6" modified="2019-10-16" version="1">MSEAPYQSQPADSFDPPKSSGSCWLYGCLGSIALLSILVVCGGVGTYWFVNNQIQKYTSETAADLPVVEIGEERLAELESRVDGFKTAVEAESTPPELILTADEINAMIAKQDDLRGRVFVKIADGQVEGDVSIPVAGRFFNGSATFDVKLVDGMLFVNLKAATIKGEPVPDMAIEAIGKENLAKELNTDPDMAKFIKSLDSVRIEGDKIILSPKVAAPEEAAGQPDASTEPADDSQPADAASDEPAAAVQND</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IW23</accession>
    <name>A0A518IW23_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">50S ribosomal protein L23</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 6" type="primary">rplW</name>
        <name evidence="6" type="ORF">Mal33_32890</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uL23 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01369_B">
        <property type="entry name" value="Ribosomal_L23_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012678">
        <property type="entry name" value="Ribosomal_L23/L15e_core_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013025">
        <property type="entry name" value="Ribosomal_L25/23"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11620">
        <property type="entry name" value="PTHR11620"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00276">
        <property type="entry name" value="Ribosomal_L23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54189">
        <property type="entry name" value="SSF54189"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV57285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="112" mass="13121" checksum="BC778EC4A8822FA7" modified="2019-10-16" version="1">MSTTTEQQVRLDAHREKGVQLESYQVLLRPLVTEKGVHRASRNNQYAFEIHKAANKDDVRAAVEDLFNVKVEKVRIQNRKGKPRRFKFRSGRSADWKKALVTLDAEHRIDFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IW90</accession>
    <name>A0A518IW90_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">4-hydroxy-tetrahydrodipicolinate synthase</fullName>
            <ecNumber evidence="3">4.3.3.7</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">dapA_2</name>
        <name evidence="3" type="ORF">Mal33_33650</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the DapA family.</text>
    </comment>
    <dbReference type="EC" id="4.3.3.7" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008840">
        <property type="term" value="F:4-hydroxy-tetrahydrodipicolinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002220">
        <property type="entry name" value="DapA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020625">
        <property type="entry name" value="Schiff_base-form_aldolases_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00701">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001365">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00146">
        <property type="entry name" value="DHPICSNTHASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01130">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00666">
        <property type="entry name" value="DHDPS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0704">Schiff base</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR001365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="311" mass="33132" checksum="70D6A356459ABA6D" modified="2019-10-16" version="1">MKTSRFPAPLSGIVPPLVTPLTAPDSLHHHGLDNLLEHLISGGVSGVFLLGTCGEGPALPFKLQCELIERACSQVDDRVPVLVGVSSPSLEDSVGLAEHAADCGASAIVSTLPYYFASAEEHQAGHLVRLARRSPLPLVVYNMPSCVHQTISIRTLQRLADEPNIAGFKDSGGDMQLFRQYCDLAIARRPEWCRLVGPEHLLAEAIAAGGTGGVNGGANVCPSLFRSIYQAAIDEDAVALHRLQKQADVLGRLYGQPETIGSVILGLKMALSLLGICEHHTTELFAPPTNEQWKATESVLAQLATWGLASV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWF3</accession>
    <name>A0A518IWF3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ATP-dependent RNA helicase HrpB</fullName>
            <ecNumber evidence="4">3.6.4.13</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">hrpB_2</name>
        <name evidence="4" type="ORF">Mal33_34170</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.6.4.13" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011709">
        <property type="entry name" value="DEAD-box_helicase_OB_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007502">
        <property type="entry name" value="Helicase-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024590">
        <property type="entry name" value="HrpA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010222">
        <property type="entry name" value="RNA_helicase_HrpA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11898">
        <property type="entry name" value="DUF3418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04408">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07717">
        <property type="entry name" value="OB_NTP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00847">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01967">
        <property type="entry name" value="DEAH_box_HrpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="2">
        <location>
            <begin position="81"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="3">
        <location>
            <begin position="282"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="607"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="607"/>
            <end position="634"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV57407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1364" mass="153437" checksum="6A93EC85DCCC93EB" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWG4</accession>
    <name>A0A518IWG4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF58 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_34410</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002881">
        <property type="entry name" value="DUF58"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01882">
        <property type="entry name" value="DUF58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="domain" description="DUF58" evidence="2">
        <location>
            <begin position="200"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="421" mass="45741" checksum="6A5D18EF0FA5794C" modified="2019-10-16" version="1">MFNTVKRSLRACFDWIPLTARGAVSIVVAGFALRYLALQEHDRLLLAACVGGLFVIAVMALAVLATGLWLRFRNLPVPDRIDAMESVQCETGLTLPLLASIPCVVVNICWLNCDGVQVDLSRGRDGCHETIRASQRMQRSEIVRQFEVGDVFGLSSVKFCRTFAQAVRVEPMPAAGCSIAQVRRDQQGDDLVHPNGKPHGDLVEMRHYRPGDPLKLVLWKHYARTRQLLVRQPENSIASMSQTIACFVAGPGDQASAGVARTIVTELKQAGEEILFQADGSAAATDSSAEAIEQIILSADARQSGGGIVAGIGSTIQDHVIKHCVAFVPSQPGAWIDRVVAGQTASQLQIDAIIGVDEPAPPRRHRFFPSWAFHRDPGDMVQLQQVQTVVDRLSAAGISTRIIHRRSGQAWSTAGYRGEVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWK2</accession>
    <name>A0A518IWK2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Thiol-disulfide oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Mal33_34840</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016209">
        <property type="term" value="F:antioxidant activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016715">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014784">
        <property type="entry name" value="Cu2_ascorb_mOase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036939">
        <property type="entry name" value="Cu2_ascorb_mOase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024548">
        <property type="entry name" value="Cu2_monoox_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008977">
        <property type="entry name" value="PHM/PNGase_F_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03712">
        <property type="entry name" value="Cu2_monoox_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="SSF47473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49742">
        <property type="entry name" value="SSF49742"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0349">Heme</keyword>
    <keyword evidence="2 4" id="KW-0408">Iron</keyword>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021835883" evidence="5">
        <location>
            <begin position="22"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="8">
        <location>
            <begin position="10"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="7">
        <location>
            <begin position="205"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="6">
        <location>
            <begin position="620"/>
            <end position="649"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV57474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="649" mass="72463" checksum="53B61B30383195BB" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWL4</accession>
    <name>A0A518IWL4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Methyltransf_11 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_34650</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="1">
        <location>
            <begin position="63"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="258" mass="28790" checksum="FC6BF4A8439613E6" modified="2019-10-16" version="1">MDVRSYNRDAWNGKVEQADRWTQPAGAEVIDAARGGDFCIVLTPTKPVPLEWFPPLKGSQTLCLASAGGQQAPVLAAAGARVTVFDNSPRQLDQDRLVAERDGLDMSFEEGDMADLSRFSDESFDLIFHPCSNDFIPNVIPVWRECFRVLRSGGILLAGFTNAVRYIFDDERKLNGNLEVRYSLPYSDLDHRNEPHIRKEIELGNPLEFGHTLEDQIGGQLKAGFMLTGFYGDRFGKSDEDPLSSFLDTFIATRAVKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWZ8</accession>
    <name>A0A518IWZ8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">META domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_36190</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005184">
        <property type="entry name" value="DUF306_Meta_HslJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038670">
        <property type="entry name" value="HslJ-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03724">
        <property type="entry name" value="META"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021811137" evidence="1">
        <location>
            <begin position="23"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="domain" description="META" evidence="2">
        <location>
            <begin position="351"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="458" mass="50671" checksum="4894EF0D9C9A4E05" modified="2019-10-16" version="1" precursor="true">MRVSSLVVVALLASLSAATAKAQPASSPRVDPLPSWNETARKQAVIDFVNRVTDRDGDDYVPPAQRIAVFDNDGTLWPEAPLPFQVEFVFEELKRRAPQEPKLAADPMVQAALAGDVKKLLAGKHYDGLMRILALTHTGITTDEFNARVETWRETTRHPRFQKAYTDLTYQPMQELLKYLRDNGFETFIVSGGGADFMRVWSEAVYGIPPQNVVGSTALTKFEFRDGKPVLIKTMDQAFVDDKDGKPVGIHQFIGRRPIACFGNSDGDQAMLEYTTIGNPLPSFGMLVHHTDAEREYAYDAHPPASGTLVTALAAAPANGWNVVDMKTDWNQIWETDKMESTQTFSEALVGNWLAEDIENHGVVDRAQTTLEIADDGTAAGNTSVNRYSGKAKISGDKIELGRMVMTRRAGPQSLMDQETRFMAALAKVTRYRIGDNGLLYLLDAEGNEIVRLSKIED</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IX75</accession>
    <name>A0A518IX75_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphodiesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_36980</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallophosphoesterase superfamily. YfcE family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024654">
        <property type="entry name" value="Calcineurin-like_PHP_lpxH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011152">
        <property type="entry name" value="Pesterase_MJ0912"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12850">
        <property type="entry name" value="Metallophos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000883">
        <property type="entry name" value="Pesterase_MJ0912"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos_2" evidence="2">
        <location>
            <begin position="1"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="250" mass="28677" checksum="26C0DAFA05BF5E49" modified="2019-10-16" version="1">MKRALISDIHGNLEALRAVLADIDSQDISEIVCLGDIIGYGPNPCECLDLVMKRCAITILGNHDQAALFDPDGFNPVALQAIYWTRDKLDSGPASESNRRWDFLGTLPRLHKAEPFMFVHGSSRDPTNEYVFPEYVYDQRKMEILFARIEHYSFQGHTHLPGVFTTQCEFLTPEECNYEYQLGPEKMMVNVGSVGQPRDEDRRSCYVVLDDESMKIEFRRIEYDVEKTAQKIYDEPDLANMLGDRIKLGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXG5</accession>
    <name>A0A518IXG5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_37940</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010799">
        <property type="entry name" value="MlrC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015995">
        <property type="entry name" value="MlrC_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07364">
        <property type="entry name" value="DUF1485"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07171">
        <property type="entry name" value="MlrC_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1485" evidence="2">
        <location>
            <begin position="4"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="MlrC_C" evidence="1">
        <location>
            <begin position="305"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="493" mass="53200" checksum="66A2770AC9582447" modified="2019-10-16" version="1">MNYRIGIVALLHESNTFITQNTTLAHFQQDTLLTGEAIRERFADAPHEVGGFFAGLGAADNVEIVPIFAARAIPYGPIEASTFDQLIETMVQQCEAAGPLDGILAAPHGATVAEGRPDADGYMLSRLRELLGPDRTLIATIDAHANVSPAMADATDALVSYRTNPHLDQRQRGVEAAQLMVKTLTSGRRLHQSAAFPPVAINIQNQNTSAMPLRPRWEAADALRELPEVASLSLVLGFPYSDVAEMGCSAILVSYEDVPAARRQELLDQLTTILTENPDCFEPEFTSPAEAVQQAGQQPGLTCMLDMGDNAGGGSPADSTILAHELHRQKIGPSLAVIFDPEAVAQVTAADFQNGSEVSIGGKTDSLHGEPLQVAVELLSTGDGKFRESEARHGGFSEFDQGATAIVRTLDSDLTLMLTSQRVPPFSLSQLTTFGIEPKEYRAIVAKGVIAPMAAYQPVADRFIHVNTQGSTCADMLQMTYHHRRQPMFPFER</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXP5</accession>
    <name>A0A518IXP5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 10">Adenylosuccinate synthetase</fullName>
            <shortName evidence="8">AMPSase</shortName>
            <shortName evidence="8">AdSS</shortName>
            <ecNumber evidence="8 10">6.3.4.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">IMP--aspartate ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 11" type="primary">purA</name>
        <name evidence="11" type="ORF">Mal33_38740</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 10">
            <text>GTP + IMP + L-aspartate = GDP + 2 H(+) + N(6)-(1,2-dicarboxyethyl)-AMP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:15753"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57567"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="6.3.4.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="8">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="8 10">Purine metabolism; AMP biosynthesis via de novo pathway; AMP from IMP: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1 8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8 10">Belongs to the adenylosuccinate synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.4" evidence="8 10"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00075">
        <property type="reaction ID" value="UER00335"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004019">
        <property type="term" value="F:adenylosuccinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044208">
        <property type="term" value="P:'de novo' AMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd03108">
        <property type="entry name" value="AdSS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.170.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00011">
        <property type="entry name" value="Adenylosucc_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018220">
        <property type="entry name" value="Adenylosuccin_syn_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033128">
        <property type="entry name" value="Adenylosuccin_syn_Lys_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042109">
        <property type="entry name" value="Adenylosuccinate_synth_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042110">
        <property type="entry name" value="Adenylosuccinate_synth_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042111">
        <property type="entry name" value="Adenylosuccinate_synth_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001114">
        <property type="entry name" value="Adenylosuccinate_synthetase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11846">
        <property type="entry name" value="PTHR11846"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00709">
        <property type="entry name" value="Adenylsucc_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00788">
        <property type="entry name" value="Adenylsucc_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00184">
        <property type="entry name" value="purA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01266">
        <property type="entry name" value="ADENYLOSUCCIN_SYN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00513">
        <property type="entry name" value="ADENYLOSUCCIN_SYN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 8 10" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 8 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 8 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 8 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 8 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 8 10" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="IMP binding" evidence="8">
        <location>
            <begin position="13"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="region of interest" description="IMP binding" evidence="8">
        <location>
            <begin position="38"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8">
        <location>
            <begin position="305"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="13"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8">
        <location>
            <position position="41"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="142"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="12"/>
            <end position="18"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="13"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="40"/>
            <end position="42"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="131"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="145"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="230"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="245"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="309"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="311"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="337"/>
            <end position="339"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="419"/>
            <end position="421"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QDV57859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="440" mass="47883" checksum="80C1F9A7EFEB0EFE" modified="2019-10-16" version="1">MPGTCVIGLQWGDEAKGKLVDLLAKDYEMVVRYAGGANAGHTVVCGDETYKLHHIPSGILHPAVQNMITPGVVINPTTLLEEIDGLAGRGVRCADNMRISERAHLVMPWHMIEDRIINEHRGVGNESIGTTNRGIGPCYRDKVGRTHAVRMTDLMQADRDERIAAVAAQKYRLLEGLGASADELASVEPSKVAAIAGGWADRLRELTGDTTEPVLAACEANRKVLFEGAQGALLDIDHGTYPFVTSSNASGVGVCAGAGVPPRWIHEVVGVCKAYSTRVGGGPFPTELHDEVGEKIRKLGNEFGTTTGRPRRCGWLDAVALRYTARLSGVSRLSLMMMDVLSHLDEIKICVAYEIDGKQTKHFPCHAEEVRRCKPVYETIPGWKIPVDDARTLEDLPEGAHRYIRRVEELIGFPVGIISVGPDRAQTIFTEQTKLDLAIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXU6</accession>
    <name>A0A518IXU6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Xylose isomerase-like TIM barrel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_39250</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013022">
        <property type="entry name" value="Xyl_isomerase-like_TIM-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01261">
        <property type="entry name" value="AP_endonuc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="SSF51658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AP_endonuc_2" evidence="1">
        <location>
            <begin position="21"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="249" mass="27995" checksum="BC5D11FF89B21C20" modified="2019-10-16" version="1">MFVAVSLESMPDLSIEDAVEIADDLEFAAVEIDLHEDGGHIRPSEILDNADTAYHRVRLSHRLDIASFSVRLQSTGDQHYEDFAELCKFAKMCKVVTMTVPSAELGTPFNEEVEHLQRLVDIAETEGCRVAVRTQIGRLSEDPDTLMVLCDNVHGLGITLDPSVFMCGPCSNKSLDRIMKYVFHVHLRDSKPDAFQVSVGQGDLDYAKLIGQLSHEKYDRAFSIHMTPIDGLDHRVELRKLRRLTESLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IY27</accession>
    <name>A0A518IY27_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_40020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="114"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="143" mass="16017" checksum="CD5DC247BAA79A5C" modified="2019-10-16" version="1">MKTATRHRLLYWYLLLFGGVVFSAFFAAAMPKAWMIATAEFFEIDSFPDHRLTWYLARHLSVVYGMLGVAVLELARDLPRYRALVLKLGWGIVVLGGLQWWVDLATGMPAIWTYGEAISTAAGGAVIVYLARDSEEPPADVDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IY80</accession>
    <name>A0A518IY80_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Ketoacyl reductase</fullName>
            <ecNumber evidence="1">1.3.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">actIII_1</name>
        <name evidence="1" type="ORF">Mal33_40570</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.3.1.-" evidence="1"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="262" mass="28017" checksum="43FAEDF5FE9FCEFD" modified="2019-10-16" version="1">MNLELNNKTALVTASTGGIGLAIATRLAAEGATTIVNGRSEESVETAIGKIRESQPKADLIGLVSDNGTAEGVARTIAEHPQIDILVNNLGIFEAVDFFDLTDEAWQHIFDINVMSGVRLARHYLKQMLEQNTGRIIFISSESGVVPAPEMPHYAMTKTAQLAVSRSLAQLTKGSCVTVNTVMPGSTLTPGVKEFVSNLFPDEPYDSAEKRFMADNRPTSLIQRLIEPEEIANMVAFVASPLASAINGAPIRVDGGLIPTIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYB0</accession>
    <name>A0A518IYB0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_40930</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="482" mass="52206" checksum="28B7701892BE49B5" modified="2019-10-16" version="1">MRSFVTLYLPRQVAVFPCDRPAGVASRFAFRLRTPRPVLMRFLCSVLCLLPTLLLWGCDSKPAEVESDSQPKAASTVPLRVAIYESEEFARRIETGWQGVSEQPLQATVVGEQELADVAANNDLIVMPARMLGTAVKAGLITSLPEKYLADESLQYQHFLPQLRETQTRWGDSIYGLSLGSPVAMTLVRDDVAEVESDQTLTYEQYGALVETLGGDKPQAAEALADGAAATAFLRRAAAAAVTPWLFEGDSFEAVIDQPPYVRALQQLVDARKHYPEKLLTAEEVWQQIVAGDLKLAIGWPIASVEAGDDASVRIFDAPVAAEVYLGKWHPNDGSIPPRSLLSGSGLVVAISSACRQSSAARNLATWMTTEGHPVLRRVSPHVSVARDELGSIESSGMQSAATGQYDRLAQTSLSSTLAHPPLRIPHADEYLAALNAAVLKALDGSMTAEEALAQTKADWQKISESADVENQKNAWNEARGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYB4</accession>
    <name>A0A518IYB4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Precorrin-6Y C(5,15)-methyltransferase [decarboxylating]</fullName>
            <ecNumber evidence="7">2.1.1.132</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">cobL</name>
        <name evidence="7" type="ORF">Mal33_40970</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; adenosylcobalamin biosynthesis.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.132" evidence="7"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00148"/>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046025">
        <property type="term" value="F:precorrin-6Y C5,15-methyltransferase (decarboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008276">
        <property type="term" value="F:protein methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd11644">
        <property type="entry name" value="Precorrin-6Y-MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000878">
        <property type="entry name" value="4pyrrol_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014777">
        <property type="entry name" value="4pyrrole_Mease_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014776">
        <property type="entry name" value="4pyrrole_Mease_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012818">
        <property type="entry name" value="CbiE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006365">
        <property type="entry name" value="Cbl_synth_CobL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014008">
        <property type="entry name" value="Cbl_synth_MTase_CbiT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00590">
        <property type="entry name" value="TP_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036428">
        <property type="entry name" value="CobL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53790">
        <property type="entry name" value="SSF53790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02467">
        <property type="entry name" value="CbiE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02469">
        <property type="entry name" value="CbiT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword evidence="3 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TP_methylase" evidence="6">
        <location>
            <begin position="3"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV58080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="411" mass="44439" checksum="F737D01DE61B00F4" modified="2019-10-16" version="1">MNKIQIVGVGDDGVEGLTNHARALIEAADVLVGPANLLPKVAIGPSERIESGSDLQRLGEMLNEMSSRNVVLLAGGDPLFYGTARFLCDSLGKDLFEVVPHVSSMQLAFARVKESWDDAYLTNLATQPLDRVVERIRTADRVGLFTTEEITPAALAAALLDRRIDYFNVYVCENLGSPDERVTQGDLSSLQGQTFGPLNVMVLVRRQGVADRPQQMEGKRLFGNPDDQFLQSKPKRGLLTPMEVRCIALALMDLGPTSIVWDVGAGSGSLAIEASQIVTGGQVYAIEMDAEDFGLMTDNAERYGCSTLIPVHGQAPEALAALPDPDVIFVGGTGRAVGELVDTIFDRLRPGGRFVVNVASPDNLVGVQAAFQRRNIEPSVRMANIARGNYQLDRLRFEAVNPSFLICGTKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYE6</accession>
    <name>A0A518IYE6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_41300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="52" mass="5965" checksum="A06ADF22D9910ABC" modified="2019-10-16" version="1">MQFCRKKLRIRLLELVNRPAEFVRRSIGSVLHMVAPSVRLVERAGTAVPYVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYF0</accession>
    <name>A0A518IYF0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_41340</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041916">
        <property type="entry name" value="Anti_sigma_zinc_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="115"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="180"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="280"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="191"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="452" mass="48109" checksum="8DA59DDE4BD302E3" modified="2019-10-16" version="1">MTMQFNEEMLTAYLDDELSSDERAIVQQTIDAEPSCAKLLEELREVRDAVAQLPPIYPSADPVAAVRQRIAAQSEVALAREQRAQTWSRLALLATAACLMLAIGSYLLRPELAPESQPTAGSIADSKPPSDPQVVDAPAADSVELRESLAYESSPLPEIQSDVYSSQADVQAVPMMKAQPPAAPFADNTVRQNRRAPQAPTRSNGQSYSRATPSLRPADSADQANRMGGGMGGSMANRSRAAVQSPTRYFFRAAESDKEDSLPLAGAPRLEDLGRGGAALESVEPAPSQQAARGAKRAMAAESEDVDRAAAPELALDDRGGLPLLEAGSAEPPRDVRRIRIQSSPDLLAVQLAQIRDLLAAEKIVSQQRQPAAGEDAGRKDVMEGYAPLRDLAKTANQPIQLVVSGSSETLQRLAEQILKTIANRATMDAPGPVSGSPEEGAVSVLQIDILP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYF3</accession>
    <name>A0A518IYF3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_41400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021994">
        <property type="entry name" value="DUF3592"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12158">
        <property type="entry name" value="DUF3592"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="139"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="204"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="235"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="438"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="466"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="591" mass="66066" checksum="9ADDEE27F8702BD9" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYM8</accession>
    <name>A0A518IYM8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glyceraldehyde-3-phosphate dehydrogenase</fullName>
            <ecNumber evidence="8">1.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">gapA</name>
        <name evidence="10" type="ORF">Mal33_42070</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.-" evidence="8"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020831">
        <property type="entry name" value="GlycerAld/Erythrose_P_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020830">
        <property type="entry name" value="GlycerAld_3-P_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020829">
        <property type="entry name" value="GlycerAld_3-P_DH_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020828">
        <property type="entry name" value="GlycerAld_3-P_DH_NAD(P)-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006424">
        <property type="entry name" value="Glyceraldehyde-3-P_DH_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43148">
        <property type="entry name" value="PTHR43148"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02800">
        <property type="entry name" value="Gp_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00044">
        <property type="entry name" value="Gp_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000149">
        <property type="entry name" value="GAP_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00078">
        <property type="entry name" value="G3PDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00846">
        <property type="entry name" value="Gp_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01534">
        <property type="entry name" value="GAPDH-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00071">
        <property type="entry name" value="GAPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 8 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gp_dh_N" evidence="9">
        <location>
            <begin position="3"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Glyceraldehyde 3-phosphate binding" evidence="4">
        <location>
            <begin position="157"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Glyceraldehyde 3-phosphate binding" evidence="4">
        <location>
            <begin position="216"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="158"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="12"/>
            <end position="13"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="79"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="126"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="188"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="239"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="323"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="site" description="Activates thiol group during catalysis" evidence="6">
        <location>
            <position position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV58190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="341" mass="36577" checksum="6357F782EC403C34" modified="2019-10-16" version="1">MAIRVAINGFGRIGRLTFRNLMERSDEFEVVAINDLTDNKTLRTLLKYDSIHGRYPGEVTYDDKSIIVDGKPIAALAERDPAKLPWGEMNVDVVIESTGFFTARATDTKPGYDSHLAAGAKKVVLSAPAKDGADLTCVMGVNDDKLTADMKCVSNASCTTNCLAPVAKVLNDTFGIESGLMTTVHAYTNDQKVQDQPHGDLYRSRAAGQNIIPTSTGAAKAVGLVIPELKGKLTGIAMRVPVPTGSVVDLTCNLSKEASVESINAAIKEAAEGPLKGILMYTEDAIVSSDIVHDPHSSVFAADFTQVLGDNGKFVKVISWYDNEWGYSSRTADLIAKFGPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ44</accession>
    <name>A0A518IZ44_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative chromosome-partitioning protein ParB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">parB</name>
        <name evidence="5" type="ORF">Mal33_43690</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ParB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041468">
        <property type="entry name" value="HTH_ParB/Spo0J"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004437">
        <property type="entry name" value="ParB/RepB/Spo0J"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003115">
        <property type="entry name" value="ParB/Sulfiredoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036086">
        <property type="entry name" value="ParB/Sulfiredoxin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17762">
        <property type="entry name" value="HTH_ParB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02195">
        <property type="entry name" value="ParBc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00470">
        <property type="entry name" value="ParB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110849">
        <property type="entry name" value="SSF110849"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00180">
        <property type="entry name" value="parB_part"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ParB" evidence="4">
        <location>
            <begin position="68"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="15"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV58351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="342" mass="37782" checksum="599F77988B24BE90" modified="2019-10-16" version="1">MTKDRRLGKGLAALLGTPIENEQGGDIGLATEPRPRRTESDGPSVQRPTKLEPSDIDDGAAAAAGQAVNLNVYEIDNNPFQPRRQFDTNEIAALAESLKSHEQLQPVIVRRDGERYQLISGERRLRAAIHAGMTTVRAEIREADDRMVAELAIVENLQRKDLNAVEKAMSFRNYIDQHGCPQNELAKRLKIDRSTVANLMRLLELPDAVLEAIQEETITAGHARALLPLGDEDLQTELTQTIIKEQWSVRQTESHVSVILQAEEDEEMGGQAAPAARKKQVTSPQISSLERQLRMDLGTKVEIKQTAKGKGKIVVHFANPEEFERITASMAGHDDVPETAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZD5</accession>
    <name>A0A518IZD5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytochrome c-552</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">cyc1</name>
        <name evidence="7" type="ORF">Mal33_44700</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13442">
        <property type="entry name" value="Cytochrome_CBB3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome c" evidence="6">
        <location>
            <begin position="68"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="6">
        <location>
            <begin position="170"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="6">
        <location>
            <begin position="271"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="250"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV58447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="365" mass="39698" checksum="A02291B9863CD68D" modified="2019-10-16" version="1">MKRRLKELCILLGGLAAIGLFVLVSGIAPINASGGHWPVTRWFLDYASDRSVDFHSSGIEPPPLDQLGMVRLGAATYDSNCRWCHGRPGRPAPVVAGHMTPSPPYLPGTPLDKEPRELFYIVKHGIKFAGMPAWPTQARDDDVWPVVAFLQQLSQLDAEDYDRQVRVETESDSAIERLAALACAACHGTATSPAAGPRVPLLASQSKAYLEQSLQAFKTGARHSGIMQPIAARLTDSQIDELAAYYAGQTQVEQEPTPPAASDSNPTASDEQIELGKSLAHRGDRQKKIAACAACHGPGTIQRSDDYPKLAGQPAWYLTQQLELLQRRARGGTDRVERMHSIADKLTAEEIEALANYYAQLPLGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZF6</accession>
    <name>A0A518IZF6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Arsenical resistance operon trans-acting repressor ArsD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">arsD</name>
        <name evidence="1" type="ORF">Mal33_44970</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046685">
        <property type="term" value="P:response to arsenic-containing substance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010712">
        <property type="entry name" value="Arsenical-R_ArsD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06953">
        <property type="entry name" value="ArsD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="123" mass="13165" checksum="9A3E3A2E2C7EAEEE" modified="2019-10-16" version="1">MTTVTIYDKAMCCSTGVCGPQVDPVLPRFAADLDWLASQGHEVKRFNLSQNPTEFVANPMVQKMLAEAGVECLPLVIVDQQIVSRGEYPSRDNLAMWTGTPLKRPTSLPVTGGGGCCGDTGCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZI8</accession>
    <name>A0A518IZI8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_45350</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="194" mass="21137" checksum="5897495A4E998C33" modified="2019-10-16" version="1">MRCLSAHQRCELHRPRGTLGSDLHSATASWFATASWLEATCWFATASWFAAVVVLLEDLAEQTAQAALLLRCTASVDAASWFATASWFAAVDSFATASWLDATCWFAAVVLLEDLAEQAAQAAFLLWGTAGVNTTDWLAANWFATACWFVSTNWLTRIAWAVATAVFTEQFVQTTKGLNVGSTCTDECNGQESW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZL2</accession>
    <name>A0A518IZL2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Heavy-metal-associated domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_45470</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00371">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017969">
        <property type="entry name" value="Heavy-metal-associated_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00403">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="SSF55008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01047">
        <property type="entry name" value="HMA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50846">
        <property type="entry name" value="HMA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="86"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="114"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="156"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="179"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="3">
        <location>
            <begin position="2"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV58524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="240" mass="26533" checksum="D0A608210D5AA0B8" modified="2019-10-16" version="1">MEKTYEITGMHCQSCVGRLTGALSELDGVDSAVVTLDPPRAHVEGSRIEFERVMEATASAGDYSAREISGAVPAPKSTPQAKSKLATYYPLILIVTFLLAGCAILQLRSRTWSWMDYMSDFMGGFFVVFGFFKLLDLRGFADAYQTYDVIASNFRRYGYLYPLIEVALGIAYLLRFELFWTNTITLIVMSVGSVGVLRSLMQKRKIQCACLGTVFELPMTTVTLVEDVGMAAMAAIMLAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZW6</accession>
    <name>A0A518IZW6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cysteine protease YraA</fullName>
            <ecNumber evidence="3">3.2.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">yraA_3</name>
        <name evidence="3" type="ORF">Mal33_46540</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C56 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.-.-" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016798">
        <property type="term" value="F:hydrolase activity, acting on glycosyl bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006286">
        <property type="entry name" value="C56_PfpI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42733">
        <property type="entry name" value="PTHR42733"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51276">
        <property type="entry name" value="PEPTIDASE_C56_PFPI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DJ-1_PfpI" evidence="2">
        <location>
            <begin position="10"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="199" mass="22142" checksum="E0A46719953DB7FA" modified="2019-10-16" version="1">MTNAPSDKPKVLIIIGDASETLDTMYPYYRLQEAGFQPVVAAPEKRLYQMVMHEVKPGWTITKEWEGYTINADVAFSEIKEEEYAGIMFSGGRAPEYIRYDEDLVRVTKHFFEAGKPIASVCHGVEIPAYADCVRGRKMATVPKCKFDLEVCGGTFVNEACVIDGNLVSGRTFHDNGFYVGPWIDLLVKARDEATVAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZY2</accession>
    <name>A0A518IZY2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alkaline phosphatase 3</fullName>
            <ecNumber evidence="2">3.1.3.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">phoB_2</name>
        <name evidence="2" type="ORF">Mal33_46180</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.3.1" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004035">
        <property type="term" value="F:alkaline phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001952">
        <property type="entry name" value="Alkaline_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11596">
        <property type="entry name" value="PTHR11596"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00245">
        <property type="entry name" value="Alk_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00098">
        <property type="entry name" value="alkPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021931283" evidence="1">
        <location>
            <begin position="29"/>
            <end position="549"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="549" mass="59252" checksum="626411F27978CA37" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J004</accession>
    <name>A0A518J004_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Peroxiredoxin</fullName>
            <ecNumber evidence="4">1.11.1.15</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">bcp_5</name>
        <name evidence="4" type="ORF">Mal33_46930</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.11.1.15" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021943524" evidence="2">
        <location>
            <begin position="25"/>
            <end position="929"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="3">
        <location>
            <begin position="775"/>
            <end position="929"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="173"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="523"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="523"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="562"/>
            <end position="590"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV58669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="929" mass="103314" checksum="CC9EA1D6EC3376A3" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J024</accession>
    <name>A0A518J024_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Protein translocase subunit SecA</fullName>
            <ecNumber evidence="10">7.4.2.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">secA</name>
        <name evidence="15" type="ORF">Mal33_47150</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell membrane</location>
            <topology evidence="10">Peripheral membrane protein</topology>
            <orientation evidence="10">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="10">Distribution is 50-50.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the SecA family.</text>
    </comment>
    <dbReference type="EC" id="7.4.2.8" evidence="10"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0065002">
        <property type="term" value="P:intracellular protein transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017038">
        <property type="term" value="P:protein import"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd18803">
        <property type="entry name" value="SF2_C_secA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01382">
        <property type="entry name" value="SecA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000185">
        <property type="entry name" value="SecA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011115">
        <property type="entry name" value="SecA_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014018">
        <property type="entry name" value="SecA_motor_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011130">
        <property type="entry name" value="SecA_preprotein_X-link_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044722">
        <property type="entry name" value="SecA_SF2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036670">
        <property type="entry name" value="SecA_X-link_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30612">
        <property type="entry name" value="PTHR30612"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07517">
        <property type="entry name" value="SecA_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01043">
        <property type="entry name" value="SecA_PP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00906">
        <property type="entry name" value="SECA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00957">
        <property type="entry name" value="SecA_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00958">
        <property type="entry name" value="SecA_PP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81767">
        <property type="entry name" value="SSF81767"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51196">
        <property type="entry name" value="SECA_MOTOR_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-1278">Translocase</keyword>
    <keyword evidence="8 10" id="KW-0811">Translocation</keyword>
    <keyword evidence="1 10" id="KW-0813">Transport</keyword>
    <feature type="domain" description="SECA_MOTOR_DEAD" evidence="14">
        <location>
            <begin position="36"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="12">
        <location>
            <begin position="122"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="13">
        <location>
            <begin position="470"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="138"/>
            <end position="142"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="552"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="QDV58691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="678" mass="76294" checksum="A35B172F891DCB8E" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J028</accession>
    <name>A0A518J028_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">DNA polymerase I</fullName>
            <ecNumber evidence="2 11">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11 15" type="primary">polA</name>
        <name evidence="15" type="ORF">Mal33_46690</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 11">
            <text>a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the DNA polymerase type-A family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="2 11"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09898">
        <property type="entry name" value="H3TH_53EXO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002562">
        <property type="entry name" value="3'-5'_exonuclease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020046">
        <property type="entry name" value="5-3_exonucl_a-hlix_arch_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002421">
        <property type="entry name" value="5-3_exonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036279">
        <property type="entry name" value="5-3_exonuclease_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019760">
        <property type="entry name" value="DNA-dir_DNA_pol_A_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001098">
        <property type="entry name" value="DNA-dir_DNA_pol_A_palm_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020045">
        <property type="entry name" value="DNA_polI_H3TH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018320">
        <property type="entry name" value="DNA_polymerase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002298">
        <property type="entry name" value="DNA_polymerase_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008918">
        <property type="entry name" value="HhH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10133">
        <property type="entry name" value="PTHR10133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01367">
        <property type="entry name" value="5_3_exonuc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02739">
        <property type="entry name" value="5_3_exonuc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00476">
        <property type="entry name" value="DNA_pol_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01612">
        <property type="entry name" value="DNA_pol_A_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00868">
        <property type="entry name" value="DNAPOLI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00474">
        <property type="entry name" value="35EXOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00475">
        <property type="entry name" value="53EXOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00279">
        <property type="entry name" value="HhH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00482">
        <property type="entry name" value="POLAc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47807">
        <property type="entry name" value="SSF47807"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="SSF56672"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00593">
        <property type="entry name" value="pola"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00447">
        <property type="entry name" value="DNA_POLYMERASE_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0227">DNA damage</keyword>
    <keyword evidence="11" id="KW-0234">DNA repair</keyword>
    <keyword evidence="11" id="KW-0235">DNA replication</keyword>
    <keyword evidence="9 11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8 11" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5 11 15" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11 15" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="53EXOc" evidence="13">
        <location>
            <begin position="7"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="3'-5' exonuclease" evidence="12">
        <location>
            <begin position="336"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="domain" description="POLAc" evidence="14">
        <location>
            <begin position="686"/>
            <end position="893"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="QDV58645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="929" mass="104727" checksum="B242E7A0D564CBC6" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J084</accession>
    <name>A0A518J084_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ABC1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ubiB_2</name>
        <name evidence="3" type="ORF">Mal33_47790</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004147">
        <property type="entry name" value="ABC1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03109">
        <property type="entry name" value="ABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="496"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="528"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="domain" description="ABC1" evidence="2">
        <location>
            <begin position="97"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="560" mass="62602" checksum="93F3B8C8EA6E9B2D" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J093</accession>
    <name>A0A518J093_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_47860</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="535" mass="60061" checksum="9202C013BA591120" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0L4</accession>
    <name>A0A518J0L4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_48970</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
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                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
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                <person name="Lage O.M."/>
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                <person name="Ovreas L."/>
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</entry>
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            <authorList>
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                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
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                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
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                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
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                <person name="Jeske O."/>
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                <person name="Lage O.M."/>
                <person name="Pohl T."/>
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                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
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                <person name="Peeters S.H."/>
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                <person name="Oberbeckmann S."/>
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    </dbReference>
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        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="6">
        <location>
            <begin position="37"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV59102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="946" mass="105201" checksum="FE11D590D4A11843" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J199</accession>
    <name>A0A518J199_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Planctomycete cytochrome C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_51420</name>
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        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
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    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="DUF1549"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
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        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022134713" evidence="1">
        <location>
            <begin position="25"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="domain" description="PSCyt1" evidence="4">
        <location>
            <begin position="202"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="PSCyt2" evidence="2">
        <location>
            <begin position="325"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="domain" description="PSD1" evidence="3">
        <location>
            <begin position="611"/>
            <end position="863"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV59116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="904" mass="101539" checksum="8E5E70EE98E1AA2B" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
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    <name>A0A518J1N7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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    <reference evidence="1 2" key="1">
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            <authorList>
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                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="1 2">Mal33</strain>
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    </reference>
    <dbReference type="EMBL" id="CP036318">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="477" mass="51529" checksum="85FC9E22A4B82F15" modified="2019-10-16" version="1">MVQIKTFGSWMMVACLIGAIGCSSSTQSPTAARGEGSGTAAEARALIDLTANAYQTASAYRDKGYVRLDYSLAGEPFEDRAPLAVSFQSPNLLSIDAYAVQLSSDGKRLQATIEDPQTNHFDGQCLSVPVSDRLTLEEVYADPMVAQFAGSGMGGPAPQLELLLSDNPLAAWLQAPAELALGKRQSVDGHACQSVVIDAEPLRYVLWIDVEDYLIRRLELPWQAIAPGLANDPQLTDASLTIELAGAEFERRLPAKVFALQTPPMSVQVTTLINPPPAAPHALVGSRVSSFRLPESTGRFDVNESGSGRPATVLMWIANHGSSQQAAVALQQAIDALPQEVQQRIHPAVVMAEPQSSADTGRMLRSWGVGMPWIDDTQAVGRDVFQITEAPCLVVLGADGSIELHQQRLNDALLQVLPAILTEVSDRQPVGRRAREQYIASQASYRRLLSQRSGLQFPLSTESNLLTAKIRSNQNLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J224</accession>
    <name>A0A518J224_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phosphohistidine phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_54220</name>
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    <organism evidence="1 2">
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        <lineage>
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            <taxon>Planctomycetia</taxon>
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    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Boedeker C."/>
                <person name="Pinto D."/>
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                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
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    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
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    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="165" mass="18211" checksum="3F196A482BBA3BF7" modified="2019-10-16" version="1">MSRLELIMMRHAKSDWGEVSLADHDRTLNNRGRRDAPRIGRWILEQDLLPDLVLCSTAVRAQQTIEAVAGEWPVEVPIHDSRTLYHAAPETIIKVVASDAMEAKRVMVVGHNPGMEMLAGHFSGACGHFPTAAILALAFEIPEWSKLRLSSQAITLAATRPKAID</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
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            <fullName evidence="2">DUF4340 domain-containing protein</fullName>
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    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025641">
        <property type="entry name" value="DUF4340"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14238">
        <property type="entry name" value="DUF4340"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4340" evidence="2">
        <location>
            <begin position="81"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="415"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="615"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="425"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="464"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="516"/>
            <end position="575"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV59407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="649" mass="70872" checksum="2C83DA447E405C7A" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ILU5</accession>
    <name>A0A518ILU5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_00030</name>
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    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetia</taxon>
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    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007922">
        <property type="entry name" value="DUF721/UPF0232"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05258">
        <property type="entry name" value="DciA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="105" mass="11879" checksum="0CF58C4AD27F94EC" modified="2019-10-16" version="1">MSREPEERKKQHARKIGSIVNQLMARRGYAQVQTGNEMERIVRRVVGDNLANTCRPGNVRNGTLEIAVSDSVSIQELSFQKRALIKALQKEFPQSGIKDIRFRAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ILV8</accession>
    <name>A0A518ILV8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Formyltransferase/hydrolase complex Fhc subunit B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">fhcB</name>
        <name evidence="1" type="ORF">Mal33_00120</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018493">
        <property type="term" value="F:formylmethanofuran dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015948">
        <property type="term" value="P:methanogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02761">
        <property type="entry name" value="MopB_FmdB-FwdB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016457">
        <property type="entry name" value="Formylmethanofuran_DH_bsu"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005646">
        <property type="entry name" value="FwdB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03129">
        <property type="entry name" value="one_C_dehyd_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="433" mass="46172" checksum="A9A4FCA2D5E5E3FD" modified="2019-10-16" version="1">MSETWNHVACPGCSCLCDDLSVQFDGDRLLSFEPACPRGEQWFRTRCESSPRGPQVAGVSVDYDSAIAVAVEILRAADYPLIYGLSQSATPGQRAAIALADALGGVADTTASLDHSAAIMALQELGEVTCTLGEIRNRADLVIFWGCDPASSHPRHAERYSIHPRGRWLPGGRSDRTVVMIGTAGQVEQCRLDAEGTTPDITIAIQPGQDFETLSILRRIVRGDQVADVPAPLEQLVPLMKSCKYGVFFYGLGLGGGGGSESSTAAPIDHVNIAALLQLVAELNAFARFTARRMGRHGEVSGADNVLCWQTGYPFAVDFSSGYPRHNPSEFSADGLLARGDVDAAVLVGAETIPRFSAAARKHLESIPTILLDHPAAQSPFQPTVEFSTAVYGLHASGTTFRMDNVPIALRAMIPTQLPTDAKILADLTNGLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ILX9</accession>
    <name>A0A518ILX9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyl transferase family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_00430</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019290">
        <property type="entry name" value="GlycosylTrfase-like_prok"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10111">
        <property type="entry name" value="Glyco_tranf_2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_tranf_2_2" evidence="1">
        <location>
            <begin position="66"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="314" mass="35656" checksum="F4530A2F83AEED47" modified="2019-10-16" version="1">MQLSALTIVRGREKHLYNQWLGLMRSSLLPAQWIIVGMDQDVALPPEVLSHRRRVQSAAASHNEASAATATQTIETKIDVRTARVDRDGEQLPLAEARNRAAELCQTDAMIFLDVDCIPAPSMLETFRQALRDDPRLWMGNVRYLPAGAASDGWQMDDLDRLAVDHPLQPRLMPGERHKSQRYELFWSLCFAATKQTFDRIGGFDPTFDGYGGEDTDFAFAARRQKVPFGFVAATAYHQHHPVCKPPLNHFHAIVRNAKRFQQKWGVWPMESWLHGFAQRGLVEFRPAEDLLRIVREPSPEEVRQARTTTAAGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMG8</accession>
    <name>A0A518IMG8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_02420</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="452" mass="50137" checksum="D221C3A75A2EA86C" modified="2019-10-16" version="1">MQKPLIVASMTLLVACTGCIQTVYKIDLKPEGNEITRTLSVKESSQNPSAQQQKQQTEELRRIETLYPEGRGDDQDGLPTFIGRFAGPMPADVGGVGTFTHFDSPLGSVSIYSERFRGNDDLAGSLATSQQAADELIDLALGWLDFEFPPSATGDADPPIDTSSIRSLLDVELRQDLKNASLQLWMYGQAESAPNNHSPIFRLAQYLAERNYFSLQQIPAIARLVQQQNPKQFILFAHDVLSRKLTLQNPDADTRCLDILKDWPRLEKSIRTYLKGTDEYKQLVAEQEQAAGAATPRHVDEAHVIGNKVMVALAPDMFSRHDLVEVALHLRQPPDSTNGTWDDDTKSVRWSQAIGDSSTPGFAFATWCVPEPEQQTLRFGSVIVRGGELFSYVIWYRGLNPDESKQWDAMLSSIGPDADAVATLQAFRFEGQPNQTLPIATMLVRLIQTAAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMN5</accession>
    <name>A0A518IMN5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptide chain release factor 2</fullName>
            <shortName evidence="4">RF-2</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 7" type="primary">prfB</name>
        <name evidence="7" type="ORF">Mal33_02880</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="4">Methylated by PrmC. Methylation increases the termination efficiency of RF2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the prokaryotic/mitochondrial release factor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016149">
        <property type="term" value="F:translation release factor activity, codon specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00094">
        <property type="entry name" value="Rel_fac_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005139">
        <property type="entry name" value="PCRF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000352">
        <property type="entry name" value="Pep_chain_release_fac_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045853">
        <property type="entry name" value="Pep_chain_release_fac_I_sf"/>
    </dbReference>
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        <property type="entry name" value="RF-1"/>
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    </dbReference>
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    <keyword evidence="3 4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
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            <begin position="210"/>
            <end position="226"/>
        </location>
    </feature>
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        <location>
            <begin position="253"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="modified residue" description="N5-methylglutamine" evidence="4">
        <location>
            <position position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV54335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="337" mass="37436" checksum="3DD6607B99B741D6" modified="2019-10-16" version="1">MAAIEKRMSEPGFWDDSEAAQAVVVELKSLKSVIGPINSSNKSAAGLDELLEMMAEEPELEADVIAEVERLEAVLDDLELRSLLNGPNDSASCILSINARDGGTDANDWADMMLRMYSAWAVKNDYSIELLDRQDNEQAGINHAAIAIRGPLAYGYLKGEEGMHRLVRISPFNSEGKRQTSFAAVSVAPEIDSSVEVEIEEKDVDEDTYRASGAGGQHVNKTDSAVRLTHRPTGVVVQCQNQRSQHQNRATAWKMLRAKLARIEEERREQEEQSKYASKARTGFGSQIRNYFLHPDQRVKDARTGHLVGNFHSVLDGSELQSFLDAFLQFRAAENAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMP4</accession>
    <name>A0A518IMP4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_03120</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="entry name" value="DUF2254_membrane"/>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="16"/>
            <end position="37"/>
        </location>
    </feature>
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        <location>
            <begin position="62"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="148"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="467" mass="51489" checksum="2512BA39D823F605" modified="2019-10-16" version="1">MNASIITLWTRVRDSYWFVPSLLVVGSILLSFATTALDESVGSDWIDDIDWLSTNQPEGARAVLSTVAGSMITVAGVTFSMTILSISHTTSQIGPRLLNNFMADKANQFTLGVFISTFIYCLMVLRTVRSAETAPPGSDAVGDLAGAFVPQIAVVIGVLMAIASVGVLIFFIHHIPETIHISNIIANIGKGINRHIDGQFPARVGEPRDEEIDRQQKLEMPDCFDSTAVQIDATTSGYLEYIDGNGLMQIACQHDLVMKIDRSPGDFVTPASLLMLVAPRERIDDDIRKELAAMFVFGVQRTTTQDLRFQINQLVEVAMRALSPGVNDPFTAISCMDWLQSALENLSARELPDSHRFDESQNLRLVATPVTFAGFASLVFDQLRPYVAADRNAALRMMTMLGDLAGQPMPLRDRRMLCRHGCALRRECDNRLTDIRTLAAIRQSYRELLKRSPSNDNPAELPNGNSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INQ8</accession>
    <name>A0A518INQ8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_06860</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="124"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="203"/>
            <end position="254"/>
        </location>
    </feature>
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        <location>
            <begin position="56"/>
            <end position="82"/>
        </location>
    </feature>
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        <location>
            <begin position="124"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="203"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="511" mass="54599" checksum="C088AB35FD9DA73A" modified="2019-10-16" version="1">MHGVTLRMTLCSVTLYTLISSTGCRTAVPDRSLQAEVQPATAPSDGLLSSLAQRFQASPNQQTRPSGTTAASAQQQKPAAPPSANMPATATLADKESDELIEAFSNATPEVQAAARQQLAAVRNMQQTQAAKPAADNAAGQPNTGQPAAGQTAAGQIAAGQVGGPTIPTPAKEISLPKPGQSKPMAHTVATVSDQVAATNNPVQQATATAPDQQSQAAVAFATPPPAESPADSTTPVEQVAAATPAAASAEPETKTIQLEAEVPAAPVAASMNPKEHLEALIKHYEEQEISLDTPGGLTQLAKLRMLYLLADKPDQAMEKVDQLNAAEQDYLRYQMMTMWSMVDPDGSPSRTRRWEKALENLRLASGHLAAATESLDVSSIAFCTEVESYGRITPFKDYKLQPGQQVILYCEIDNFASERLSDGYETHFQGSYDLFNADGVRVAEQVLPADKQSCNNYRRDYFIAYRLYLPKQLAPGPHRIQLTIEDLKGKKFGQSTLDFEIVAKAEAPAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP50</accession>
    <name>A0A518IP50_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Serine-aspartate repeat-containing protein I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">sdrI_1</name>
        <name evidence="5" type="ORF">Mal33_08400</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044048">
        <property type="entry name" value="Big_12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002105">
        <property type="entry name" value="Dockerin_1_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013517">
        <property type="entry name" value="FG-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017868">
        <property type="entry name" value="Filamin/ABP280_repeat-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028994">
        <property type="entry name" value="Integrin_alpha_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033764">
        <property type="entry name" value="Sdr_B"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19078">
        <property type="entry name" value="Big_12"/>
        <property type="match status" value="21"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00404">
        <property type="entry name" value="Dockerin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13517">
        <property type="entry name" value="FG-GAP_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17210">
        <property type="entry name" value="SdrD_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69318">
        <property type="entry name" value="SSF69318"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50194">
        <property type="entry name" value="FILAMIN_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="SdrD_B" evidence="3">
        <location>
            <begin position="932"/>
            <end position="1028"/>
        </location>
    </feature>
    <feature type="domain" description="Big_12" evidence="4">
        <location>
            <begin position="1867"/>
            <end position="1943"/>
        </location>
    </feature>
    <feature type="domain" description="Big_12" evidence="4">
        <location>
            <begin position="1952"/>
            <end position="2042"/>
        </location>
    </feature>
    <feature type="domain" description="Big_12" evidence="4">
        <location>
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            <end position="2233"/>
        </location>
    </feature>
    <feature type="domain" description="Big_12" evidence="4">
        <location>
            <begin position="2248"/>
            <end position="2331"/>
        </location>
    </feature>
    <feature type="domain" description="Big_12" evidence="4">
        <location>
            <begin position="2342"/>
            <end position="2436"/>
        </location>
    </feature>
    <feature type="domain" description="Big_12" evidence="4">
        <location>
            <begin position="2444"/>
            <end position="2531"/>
        </location>
    </feature>
    <feature type="domain" description="Big_12" evidence="4">
        <location>
            <begin position="2542"/>
            <end position="2626"/>
        </location>
    </feature>
    <feature type="domain" description="Big_12" evidence="4">
        <location>
            <begin position="2641"/>
            <end position="2722"/>
        </location>
    </feature>
    <feature type="domain" description="Big_12" evidence="4">
        <location>
            <begin position="2732"/>
            <end position="2826"/>
        </location>
    </feature>
    <feature type="domain" description="Big_12" evidence="4">
        <location>
            <begin position="2835"/>
            <end position="2923"/>
        </location>
    </feature>
    <feature type="domain" description="Big_12" evidence="4">
        <location>
            <begin position="2927"/>
            <end position="3017"/>
        </location>
    </feature>
    <feature type="domain" description="Big_12" evidence="4">
        <location>
            <begin position="3028"/>
            <end position="3112"/>
        </location>
    </feature>
    <feature type="domain" description="Big_12" evidence="4">
        <location>
            <begin position="3122"/>
            <end position="3216"/>
        </location>
    </feature>
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        <location>
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            <end position="3310"/>
        </location>
    </feature>
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        <location>
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        </location>
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        </location>
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            <end position="3606"/>
        </location>
    </feature>
    <feature type="domain" description="Big_12" evidence="4">
        <location>
            <begin position="3614"/>
            <end position="3701"/>
        </location>
    </feature>
    <feature type="domain" description="Big_12" evidence="4">
        <location>
            <begin position="3708"/>
            <end position="3797"/>
        </location>
    </feature>
    <feature type="domain" description="Big_12" evidence="4">
        <location>
            <begin position="3808"/>
            <end position="3892"/>
        </location>
    </feature>
    <feature type="domain" description="Big_12" evidence="4">
        <location>
            <begin position="3902"/>
            <end position="3991"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="4219"/>
            <end position="4262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="4221"/>
            <end position="4245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF19078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV54875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="4273" mass="437287" checksum="4CDDC7D9A6489931" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPB4</accession>
    <name>A0A518IPB4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_08830</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="103" mass="11370" checksum="A1A42FA7B7FB338C" modified="2019-10-16" version="1">MPPKTNDLLAQTPVEPRKAFHAISHVLNAGFAALGASPKVTVSHRRKSRGHKGTSDRWTISIEFCEPDQQRAAIVGLLRRLAEHDPAARQYLFDMGEPATDNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPF8</accession>
    <name>A0A518IPF8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Flagellar hook-basal body complex protein FliE</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">fliE</name>
        <name evidence="5" type="ORF">Mal33_09490</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 3">Bacterial flagellum basal body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the FliE family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009425">
        <property type="term" value="C:bacterial-type flagellum basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003774">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR001624">
        <property type="entry name" value="FliE"/>
    </dbReference>
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        <property type="entry name" value="PTHR34653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02049">
        <property type="entry name" value="FliE"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="FLGHOOKFLIE"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00205">
        <property type="entry name" value="fliE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="5" id="KW-0966">Cell projection</keyword>
    <keyword evidence="5" id="KW-0969">Cilium</keyword>
    <keyword evidence="5" id="KW-0282">Flagellum</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
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        </source>
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    <evidence type="ECO:0000256" key="3">
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        </source>
    </evidence>
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            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV54981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="101" mass="11279" checksum="16786142B21E170F" modified="2019-10-16" version="1">MNPVSLRIPPAQMPLAPPVPGTQPVEPGYKQFTDLLVDGFQEVNAAQNSANASVHDMLTGKDVDRIEVLTSVQKADMSFRLMQQIRNKLVEAYREINQMQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPI6</accession>
    <name>A0A518IPI6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">RNA polymerase sigma factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_09710</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="term" value="P:DNA-templated transcription, initiation"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07638">
        <property type="entry name" value="Sigma70_ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
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    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="202" mass="23198" checksum="F25DFD8D9FA9B623" modified="2019-10-16" version="1">MDEHDSIDLFARVREGEKEAEFELFDHYVVRLLGLVRKRISPQFARRIEAEDVVQSAYRSFFSGVQDDRFVLQNSGDLWRLLAAITMHKLHRQLERNKAAKRSVKREHSIQLQLGDSSCTFSVDAVASEPTPEDEVALSEEIGLLMSSFDTGQQTMFEMRLAGATIDEIAARMECSERTVRRFFDRKVKPMLEARFGLPQPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPK7</accession>
    <name>A0A518IPK7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Gluconate 5-dehydrogenase</fullName>
            <ecNumber evidence="1">1.1.1.69</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">gno_1</name>
        <name evidence="1" type="ORF">Mal33_09650</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.1.69" evidence="1"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008874">
        <property type="term" value="F:gluconate 5-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="258" mass="26726" checksum="D581B71B763E0E27" modified="2019-10-16" version="1">MALPGIKLFDLTGKSAIVTGGSKGLGQAMAAGLASAGADVMLVSRSQQEAADAAKQIADEFGHQAFGIAADVSCPDQVESMVAQAIDRFGKIDILINSAGINIRGSIESLTLDEFRQVQSINTDAMWSCCKAVVPHMKRSGAGKIINMASTLGLVGLANRTPYATSKGAVVQLTRALGLELAGDGIQVNAICPGPFLTPMNAPIAETEEGKQFIVGATAVKRWGQLEEIQGAAIYLASPASNYMVGSMVVVDGGWTAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPM7</accession>
    <name>A0A518IPM7_9BACT</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_10240</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="78" mass="8730" checksum="C333518FC1A9E909" modified="2019-10-16" version="1">MTNPITDQIRELRHRLAADFDNDLDRIYADLQRKEKASGRVVIDLRGERVATDCQAMQQSGGGKLSPADHKSPPLGER</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPP1</accession>
    <name>A0A518IPP1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_10340</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="102" mass="11136" checksum="FBEBC8D92510129D" modified="2019-10-16" version="1">MWAGEVLGIFTRSAKQGGSENKRLASFSGKSYHKVGPARICRAPPPRTSLRLFDPPLPNFVCWRVKLAVLHAVKLKGTLRESRLASEAGVGEVVFGKTFVAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPQ0</accession>
    <name>A0A518IPQ0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Tripartite tricarboxylate transporter TctA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_10330</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002823">
        <property type="entry name" value="DUF112_TM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01970">
        <property type="entry name" value="TctA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="142"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="170"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="194"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="270"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="337"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="380"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="411"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="491"/>
            <end position="508"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="519" mass="54634" checksum="FCBEEB184985E48C" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPS6</accession>
    <name>A0A518IPS6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ECF RNA polymerase sigma factor SigE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">sigE_2</name>
        <name evidence="7" type="ORF">Mal33_10520</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007630">
        <property type="entry name" value="RNA_pol_sigma70_r4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04545">
        <property type="entry name" value="Sigma70_r4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="5">
        <location>
            <begin position="43"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4" evidence="6">
        <location>
            <begin position="128"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV55083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="187" mass="21263" checksum="01F61FC8DCD512DB" modified="2019-10-16" version="1">MQDVRSGDPAALDELLALTGHYLNEASARYPLPANIRSKLSDSDLVQNTLLEIAQDLAKFRGTNQAAFLDWAQRTLRNNFVDARRKFHDAERRDVRREVELESGLFHREGSPSRIVKRAERDEQLEQAIAALPDRARKVIELRNIKGMSWEAVGDRLDVSADAARKLWTRAVKRLQEILAVQESSFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPT1</accession>
    <name>A0A518IPT1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_10740</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="297"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="301"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="350"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="377"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="391" mass="43170" checksum="13CB82B2C5F0B919" modified="2019-10-16" version="1">MNPRGPNSEPSHRQRWLQILLTLSVTWVAGGATCYRGKAVTDFSPPPEIFEGTPSREELAAAVNRTDRIEKLQSTSASIKVLSMPALPSLRANLALERPRRIRMRASLPVVMGSGMDLGSNEELFWMKIPEGMGTSLYFARHEDYQRQLQRAILPVDPTWLVDALGMAHIDVNQIEEGPTVRADGKLELKLSQPMVDGTYRRVMVIDQRQGVVTELLLYGPDGRLLANASGEDFRYFEEVQCSLPHDVQLRLTPNGGEPLALKIEIGSYSVNQLLSDDPRLFAMPEDGNERPIDLTRIGQPPMSPVPPTYTVPPPQANYAPLQGFPPPTASPPPANYPQTNYPPPQAQAAMPAANYPPPQPQYAPQQPPYAPASGYVPQVSQGTTYRGVYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQ59</accession>
    <name>A0A518IQ59_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_12010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="89" mass="9504" checksum="50F883545330CDA1" modified="2019-10-16" version="1">MARSYAVSLGAMALGLIALRGAINSDDLSSVVTLGLFGMVVASGVGYIIGAIADQVICQTVEVRFRQRLAEVIEHFNEMEADKQNSRTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQD9</accession>
    <name>A0A518IQD9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">T2SS-T3SS_pil_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_12620</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032789">
        <property type="entry name" value="T2SS-T3SS_pil_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13629">
        <property type="entry name" value="T2SS-T3SS_pil_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022057541" description="T2SS-T3SS_pil_N domain-containing protein" evidence="2">
        <location>
            <begin position="33"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="domain" description="T2SS-T3SS_pil_N" evidence="3">
        <location>
            <begin position="394"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="232"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="271"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV55292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="534" mass="56964" checksum="E94903E7E1F6989A" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQE2</accession>
    <name>A0A518IQE2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Outer membrane biogenesis protein BamB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_12720</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002372">
        <property type="entry name" value="PQQ_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13360">
        <property type="entry name" value="PQQ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021864384" evidence="1">
        <location>
            <begin position="26"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="434" mass="46676" checksum="91A17A2B696239A5" modified="2019-10-16" version="1" precursor="true">MKTNDRLPMMVKILCLFLPATSLFGQSTDWPQWRGPHRDGKAAEQALLQEWPEGGPKLKWTFRDCGVGYSGFSIVGDQLFTMGLEEGQCYVIALKPSDGSELWRTPIGPAAKEDAYLMGWGGGPRSTPTVDGDHLYALSDAGVLACLKTADGELVWKVSLVDDFGGSIPKWGYSESALIDGDRVIVTPGGKNFMIGLDKRTGKKIWGSEGIEAKAQYASVIKHTVDGITFYVTASNPGLIAVDATSGKQVFADTGTANGVAVIPTPIATGDFVYHTSAYDAGNTLVKLAKGDSGTLAVEPVYSLSKESKSMENHHGGVVLVDGVIYGFTKTNRGNWMAQDFQTGDTLWMESVGKTRSGSIAYADGRLYCYGDQDGSVVLAEPSRNGLVVKGKLVLPEQTDIDRGKGAIWAHPVIAGNTLFLRDQDLVFAFDLKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQJ0</accession>
    <name>A0A518IQJ0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_13330</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="175" mass="20066" checksum="060E084C839F6246" modified="2019-10-16" version="1">MASRSKIVWLMYLRYEGRSPIMSVLEQSNFGDSATAEKWAKTREKSWIEKMIEDKAPILNGAKWSGDPSRKAIPKGVKTAWCETHVLLWAIDRSWRDERRLLTCLNDRYGSIMLETPQPNGSTLCESMAEIPLAQSQYEGRRYRACSVLRALLQAHPQLEVCDIQTLIDFECSIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQL2</accession>
    <name>A0A518IQL2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_13530</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="212" mass="24041" checksum="9B3BAACCB15CED09" modified="2019-10-16" version="1">MVKRILERLCFVALASIGSVSCAEESIAFCMPEWKEMHFDDGAKAQLHLAAVQKLGCEAKIDNHGSHIDVVYRSPKWKSLEVADDKLAHQWESWLKKAGFETLHGHAADHGGDDHAGHEGHDHSYTAGQIEEVNYRVSEWKTMHIETKEQITELTAMLKGLGCELKISQHSGHADLSFRCQQWKHIEVGSHQVATTWEQWLVKMGFEVKHDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQT7</accession>
    <name>A0A518IQT7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_13960</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021833697" evidence="1">
        <location>
            <begin position="29"/>
            <end position="510"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="510" mass="56521" checksum="9740CBF74429B1AB" modified="2019-10-16" version="1" precursor="true">MNLSTLAGGLSVAVLLLCSGMPARHTHAAGVLKLQIMDRQTNEPVAARVVMIGPRGREVPVRRATAAGVGWAIDSQIDLEVPSGDFQFHLTRGPEYRIMTGNFQIDRTAEDTHTITLERFVDTQAEGWLCGDLFVDHKLRDLPLLMRAEDLDIIALATRSSDGKATAAEPPTDPIDCGSDTMQIATDNVIDRREGSGLLIVGGNPEIDSVDADSPSSLLFRAAMDDPDARFVVENPFAWDLPIWLASGRVAGFAVMGDFLQLDRSISRVTNGRPATEPEYDNPLGLGFWADDIYRHLLDAGFRIPPVAGSGSGNRAVKNPLGYNRVYVHAGDQPTPAAFWEGLWQGKSVVTNGPLLRPRLALQYPGHVFASYGDEPQVLQMDLQLGTRDPVEYLEVIYNGSVIYSARLEEFKDDKGIIPPFTFDRSGWVVARVVTGYEKHYRAAVSAPWYIEIPGKPRISRASVEFFIDWLQQREQMLRKKSPEYIRSVSPFVRAARQFWEERLAQATVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQV5</accession>
    <name>A0A518IQV5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_14510</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="136" mass="15182" checksum="E5520A95FC089791" modified="2019-10-16" version="1">MSKATIPNTDDYGCHVDRDPLLVYIPLVLIWNGHDLTWHPETMDLQAAERLVTSINIHPGCFAKVVMVNMVVPAAAEIAKHLDAESFEHDLLMADWVRLGLRVERDPPVVDRERPRVPFVPNVFPAAGHAGSEVTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IR52</accession>
    <name>A0A518IR52_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_15540</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008930">
        <property type="entry name" value="Terpenoid_cyclase/PrenylTrfase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48239">
        <property type="entry name" value="SSF48239"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022235057" evidence="1">
        <location>
            <begin position="20"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="362" mass="39599" checksum="1BCACE47118BCB22" modified="2019-10-16" version="1" precursor="true">MLRPLLCCFAALLTLPSIAADRQQETDAAIARGIDFLTRGAASDTGAYSPQTGTGVTSLCITAVLQNRPAMATSPSIVKSLKFLEQHFQDTGGIYVNDSLYRNYETSLAMQALALANSDHRYDQRLKRAEAFLRGIQWDEGEGIESSDPGYGGAGYGKHARPDLSNTQFFLDALRSVGVGEEDPAIQKALKFVSRCQNLESEYNDTPHAAKVGDGGFYYTSAAGGQSQAGQTPDGGLRSYGSMTYAGLKSMIYAGVSKDDQRVKAAMDFIRKTYSLQQNPGMGNAGLFYYYHTFAKALDATQLKTIEDASGQKHDWRQELSETLLSLQAEDGAWVNRENERWLEGDRNLVTAYALMALSYCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IR84</accession>
    <name>A0A518IR84_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">30S ribosomal protein S6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">rpsF</name>
        <name evidence="7" type="ORF">Mal33_15840</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Binds together with S18 to 16S ribosomal RNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the bacterial ribosomal protein bS6 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00473">
        <property type="entry name" value="bS6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00360">
        <property type="entry name" value="Ribosomal_S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000529">
        <property type="entry name" value="Ribosomal_S6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020814">
        <property type="entry name" value="Ribosomal_S6_plastid/chlpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035980">
        <property type="entry name" value="Ribosomal_S6_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014717">
        <property type="entry name" value="Transl_elong_EF1B/ribosomal_S6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01250">
        <property type="entry name" value="Ribosomal_S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54995">
        <property type="entry name" value="SSF54995"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00166">
        <property type="entry name" value="S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="110"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV55607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="134" mass="14847" checksum="CF4FB3E7484E0A91" modified="2019-10-16" version="1">MVTHISTYETLFILDSNHYARDPNGVGKSVAAMIEEVGGKVLVSRLWAEQKLAYPIDGHFKGTYWLAYFEMEGTKLTELNRACQLSESIVRHMSLKLDKRLVEPMVAHARGESISTEGTGEESTEVEAAEVAAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRR2</accession>
    <name>A0A518IRR2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">4-hydroxyproline betaine 2-epimerase</fullName>
            <ecNumber evidence="2">5.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">hpbD</name>
        <name evidence="2" type="ORF">Mal33_17510</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="5.1.1.-" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016836">
        <property type="term" value="F:hydro-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034620">
        <property type="entry name" value="Cis-3-h-L-Pro_dehydratase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036849">
        <property type="entry name" value="Enolase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029017">
        <property type="entry name" value="Enolase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029065">
        <property type="entry name" value="Enolase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013342">
        <property type="entry name" value="Mandelate_racemase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013341">
        <property type="entry name" value="Mandelate_racemase_N_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13378">
        <property type="entry name" value="MR_MLE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02746">
        <property type="entry name" value="MR_MLE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00555">
        <property type="entry name" value="cis-3-hydroxy-L-proline_dehydr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00922">
        <property type="entry name" value="MR_MLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51604">
        <property type="entry name" value="SSF51604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54826">
        <property type="entry name" value="SSF54826"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MR_MLE" evidence="1">
        <location>
            <begin position="144"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="367" mass="39805" checksum="7FA5CC71165CADAF" modified="2019-10-16" version="1">MKITRISAHRVELPLIEGAYHWSGGKSVNVFDSTIVAVETAEGLVGYGEVCPLGPFYLPAYAEGVRAGLRELGPHLIGLDPRELGVLNQRMDAALKGHPYVKSGIDIACWDLLGKASGLPVCMLMGGRFGESVRLYRAISQIAPDAMAENVASYRDQGYTRFQLKVGGDPDTDIQRIRAARDVLRPSDRLVADANTGWTQHEAQRVVRAVADLDVYIEQPCLTYEECLAVRRNTTHPFILDENIDGLEMLFRAKADLAMDVVNLKISKLGGLTKARQARDVCASMGIAMTIEDSWGGDITTAAIAHLAHSTPESLRFTSTDFNSYVTVCNADGAPKREHGFMQASAAPGLGITPHFDVIGPAVVEVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IS03</accession>
    <name>A0A518IS03_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">N-acetylmannosaminyltransferase</fullName>
            <ecNumber evidence="1">2.4.1.187</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">tagA_1</name>
        <name evidence="1" type="ORF">Mal33_18540</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.4.1.187" evidence="1"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047244">
        <property type="term" value="F:N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06533">
        <property type="entry name" value="Glyco_transf_WecG_TagA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004629">
        <property type="entry name" value="WecG_TagA_CpsF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34136">
        <property type="entry name" value="PTHR34136"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03808">
        <property type="entry name" value="Glyco_tran_WecG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00696">
        <property type="entry name" value="wecG_tagA_cpsF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="268" mass="29806" checksum="54B7B469F2D7205F" modified="2019-10-16" version="1">MIDSGKYSVIGVNVDAVDYEAAVAKIMHAAIERQSMAVTALAVHGVMTGYLDREQNYRLNRFDLVCPDGQPVRWALNLLHGCGLSDRVYGPELTLRLCQACVEQQQSIFLFGGTDGMNAVLIDKLAEKFPGLRVAGARASRFRTLSPEECSELADEINASGASLCFVGIGCPRQETFAFEMRDRISMPLIAVGAAFAFHANLLPQAPSWMQRAGLEWLFRLVKEPTRLWRRYLYLNPMYLSLLALQRLGIFKGRTDDGTPPQQEVLFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IS47</accession>
    <name>A0A518IS47_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ankyrin repeats (3 copies)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_18980</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="SSF48403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="137"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="165"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="266" mass="29768" checksum="A9CA5C8A14B84AD6" modified="2019-10-16" version="1">MHLDDAIELSSRAGGIDSVEITPDLERKLRGLINQLCDEEFPEPDFEHTAIAVSYRQWTLTTELSGVTSFYHESELAGPRNRCMRNIEIEDLLKMYLMLAAADIDGLLKQSWKPFDDLPDEEGHFYLYRSDPLCNELHKAASMGNVAAIKPLLDRGFDLEARDGMGYTALHRATFVPHVEVMEELLRLGADVEAPCPDGETPLFSVAVCEYNWLLLDAAKVLIKHGANVNATKSTNYTVLENANVYGNTEFQQLLRDHGATAPQAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IS71</accession>
    <name>A0A518IS71_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein-glutamine gamma-glutamyltransferase</fullName>
            <ecNumber evidence="2">2.3.2.13</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">tgpA_2</name>
        <name evidence="2" type="ORF">Mal33_18820</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.3.2.13" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003810">
        <property type="term" value="F:protein-glutamine gamma-glutamyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013589">
        <property type="entry name" value="Bac_transglu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002931">
        <property type="entry name" value="Transglutaminase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08379">
        <property type="entry name" value="Bact_transglu_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01841">
        <property type="entry name" value="Transglut_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00460">
        <property type="entry name" value="TGc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TGc" evidence="1">
        <location>
            <begin position="177"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="296" mass="33066" checksum="B09A27FB0FAC7F80" modified="2019-10-16" version="1">MKYRITHTTKYNYSQPVGVCHNKIHLAARSLPQQTVTNFHLLIKPDAFASTCQKDYFGNRVDYFSIQEPHRSLTVTATSNVEVRPITRPPAFTASPPWEDVAQGIAKRRDELSLSAYQFSFASRIVPRDPAYAEYTLASFTKGRPIVEAGLDLTRRIFEDFKYDPRATTVSTPVDVVFKQRAGVCQDFAHLQIACLRSIGLASRYVSGYLRTLPPPGKERLIGNDQSHAWLSLYCGDEIGWVDFDPTNNMIPATDHITIGWGQDYSDLCPIQGVFIGGGKNRMDVSVDVATISPDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IS83</accession>
    <name>A0A518IS83_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NAD kinase</fullName>
            <ecNumber evidence="5">2.7.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">ATP-dependent NAD kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ppnK</name>
        <name evidence="5" type="synonym">nadK</name>
        <name evidence="6" type="ORF">Mal33_19340</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + NAD(+) = ADP + H(+) + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:18629"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the NAD kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.23" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003951">
        <property type="term" value="F:NAD+ kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019674">
        <property type="term" value="P:NAD metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006741">
        <property type="term" value="P:NADP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00361">
        <property type="entry name" value="NAD_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017438">
        <property type="entry name" value="ATP-NAD_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017437">
        <property type="entry name" value="ATP-NAD_kinase_PpnK-typ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002504">
        <property type="entry name" value="NADK"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01513">
        <property type="entry name" value="NAD_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="SSF111331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5 6" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 5" id="KW-0520">NAD</keyword>
    <keyword evidence="3 5" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5 6" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="77"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="77"/>
            <end position="78"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="151"/>
            <end position="152"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="162"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="192"/>
            <end position="197"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV55955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="299" mass="32297" checksum="70D31CD9A5354925" modified="2019-10-16" version="1">MSQSESSDEKRPCWPRAGRSRPDVVVVGALDRPSVASELNRLRSLIAERAEIAAVDLDFSYDFEHAQHDLVIVLGGDGSILQTARQMGENQLPILGVNCGHLGFLAALTPDAFLDIWGTVANGDCELVDHLMLRASIIRDGEEVAVQLGLNEAAILGGPPYRILNIDLSVDQVHATSYSCDGLIISTPIGSTAHNLSAGGPILRKNLQAFVISPISPHTLTHRSVVDTADRTFDLSVANPNDSTSLVVDGRVVDVIQPGDRIRVQRSPYSFQMVAVPGQNDYRTLREKLGWSGNTISKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IS85</accession>
    <name>A0A518IS85_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">HTH-type transcriptional repressor NicR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">nicR</name>
        <name evidence="3" type="ORF">Mal33_19450</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023187">
        <property type="entry name" value="Tscrpt_reg_MarR-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01047">
        <property type="entry name" value="MarR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00598">
        <property type="entry name" value="HTHMARR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01117">
        <property type="entry name" value="HTH_MARR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="2">
        <location>
            <begin position="101"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="242"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="265" mass="29056" checksum="C3ADCFB7D9B3994B" modified="2019-10-16" version="1">MAQFPFMRLPRENEVSRGRSFDRNRKCFELKVLLPQCRWMCCQRWRVASQSGSGAARSAPGEWLGVLSRPRNDFAVTLVNDAGGGKRAIGMKTKVPVLSNEDQIVAAIRQIIRAVDLHSRHLVNGHGMTGPQLAVLQEAKRLGPVSPTALSRAVHLSQATVTGILQRLERRGLIQREQSVSDRRSVSVQTTSAGLEFLSGSPSLLQDRFRDALSALEDWERLQILSTLQRVASLMDADEIDAAPHLTSGDIPTPSDDLSGPGESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISA0</accession>
    <name>A0A518ISA0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_19120</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="26"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="181"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="911" mass="99591" checksum="AAF9758470C87C8A" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISI0</accession>
    <name>A0A518ISI0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_19920</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
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            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="160" mass="17342" checksum="13558EE01091BBDD" modified="2019-10-16" version="1">MLNWMDHVDTYLQQLNETSDALAGTLVGLEQATRKADSEEINSACAKLGSLLRVLEQQLSQREALLVEFPDAADTAPANLQSALGTIEHPRASELAKRCTLISSELRGIHQKAISLFVGQYHLTSVTEELLRLMSGVSAKPITYDAADDDTGGSFLDRAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISL8</accession>
    <name>A0A518ISL8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_20700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="102" mass="11138" checksum="CFBBEBED65A38588" modified="2019-10-16" version="1">MRAPGRWPFTGWECVGDAPAVTEPCRLGYANCWTFGPRSMLADYAFPVASPYFPLVCLGGSPDLAAGVAAQPVDRPMKSPKTHDCSALRNPNNRYPADNCYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITC2</accession>
    <name>A0A518ITC2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Enoyl-[acyl-carrier-protein] reductase [NADH]</fullName>
            <ecNumber evidence="6">1.3.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">fabI_1</name>
        <name evidence="10" type="ORF">Mal33_23020</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a 2,3-saturated acyl-[ACP] + NAD(+) = a (2E)-enoyl-[ACP] + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:10240"/>
            <dbReference type="Rhea" id="RHEA-COMP:9925"/>
            <dbReference type="Rhea" id="RHEA-COMP:9926"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:78784"/>
            <dbReference type="ChEBI" id="CHEBI:78785"/>
            <dbReference type="EC" id="1.3.1.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.9" evidence="6"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00705"/>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004318">
        <property type="term" value="F:enoyl-[acyl-carrier-protein] reductase (NADH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016631">
        <property type="term" value="F:enoyl-[acyl-carrier-protein] reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05372">
        <property type="entry name" value="ENR_SDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014358">
        <property type="entry name" value="Enoyl-ACP_Rdtase_NADH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43159">
        <property type="entry name" value="PTHR43159"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000094">
        <property type="entry name" value="Enoyl-ACP_rdct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="5 6" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="6" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="5 6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="4 6 9" id="KW-0520">NAD</keyword>
    <keyword evidence="3 6 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="152"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="162"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="12"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="18"/>
            <end position="19"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="71"/>
            <end position="72"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="198"/>
            <end position="202"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR000094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000094-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000094-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000094-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV56320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="274" mass="29404" checksum="535CB385D06F874E" modified="2019-10-16" version="1">MDFTGKKGLVLGVANDHSIAWAIAQELLEGGAEVGFTHLPDRPDDERRKNRTRVSKLTDKYPNAKFLEPLDVSNDEQIAGIMAKAKEEFGTIDFLLHSIAFADRADLGRETIETSRDGFKLAMDISVYSLIAVCNAARSILADGASVATMTYFGGEKCVPGYNVMGICKAALEASMRYLAYDLGQQGVRVNALSAGPVRTLAGKAAGVDEMLSLYEHMAPLGRNITHGEVGKTGAFLLSPASQGITGEILHIDGGYHAMGSPGRLLEKIKQQQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITC4</accession>
    <name>A0A518ITC4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">GDP-mannose 4,6-dehydratase</fullName>
            <ecNumber evidence="3 4">4.2.1.47</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">GDP-D-mannose dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">gmd_1</name>
        <name evidence="4" type="synonym">gmd</name>
        <name evidence="6" type="ORF">Mal33_23190</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>GDP-alpha-D-mannose = GDP-4-dehydro-alpha-D-rhamnose + H2O</text>
            <dbReference type="Rhea" id="RHEA:23820"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57527"/>
            <dbReference type="ChEBI" id="CHEBI:57964"/>
            <dbReference type="EC" id="4.2.1.47"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 4">
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.47" evidence="3 4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008446">
        <property type="term" value="F:GDP-mannose 4,6-dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070401">
        <property type="term" value="F:NADP+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019673">
        <property type="term" value="P:GDP-mannose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00955">
        <property type="entry name" value="GDP_Man_dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006368">
        <property type="entry name" value="GDP_Man_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43715">
        <property type="entry name" value="PTHR43715"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01472">
        <property type="entry name" value="gmd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="5">
        <location>
            <begin position="8"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV56337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="342" mass="38797" checksum="B315198E30D1FCB6" modified="2019-10-16" version="1">MADQKSALITGITGQDGSYLAELLLDKGYLVHGLVRRSSTFGTERIDHIYQDLHANPTLMLHYGDLTDGQALTNLVLDIKPDEIYNLGAQSHVRVSFDQPVYTLHTVGVGALNVLEAARQLQKLKEVRVYQASSSEMYGDVLQTPQTETTPFNPQSPYACAKVYAFHQTVNYRESYGMFACNGILFNHESERRGETFVTRKITRAATRIKAGLQKKLYLGNLDAKRDWGYAKDYVEGMWRILQHSEPDDFVLATGETQSVREFLRLVFEQLELNWEDYVEIDPRYFRPAEVELLLGDPSKAKEKLGWTASTDLRELARIMVEHDLELAQREAHAKTFVAGDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITE8</accession>
    <name>A0A518ITE8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SGNH_hydro domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_23320</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021800153" description="SGNH_hydro domain-containing protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="domain" description="SGNH_hydro" evidence="2">
        <location>
            <begin position="73"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="455" mass="50116" checksum="3FC7AFC4721C2F5A" modified="2019-10-16" version="1" precursor="true">MFRSLALCTLLSPLFAFTALGQPATSPAAPPKLGPYLYETKPDDPAFASFNPRRAPQPGELLLRKGDRLAICGDSITEQKMYSRLIETYLTVCVPELQITARQYGWSGEKTDGFLRRMEKDCLTFSPTIATLAYGMNDSRYRPFDVTNGQWYEDHYTAIVRKFKANDVRVVVGSPGCAGKIATWVKSRSGTLEQHNLNLCALRDIAIGVAEAEQVRFADIFWPMLQAQVFAPAQHGATEEKPYRVAGSDGIHPGWAGQVIMAWTMLRSLGLDGNLGTIEIDTDKNTATANGGHSIDSYADGVATVTSTRYPFCATGTLHSENSIRSGMTLAPFNEDLNRFLLKVNAAEGTKWEITWGDQTQTYTADQLAQGINLAWEFPKNPFSESFDRVDAAVAKKQAYETLQVKKIFHGPEGKKDFDTAVKETEAVRKPLADAIADAMQPVTHKIAIRQVAGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITP0</accession>
    <name>A0A518ITP0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_24490</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="147"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="151"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="172" mass="19332" checksum="4CDA47BB30A652CA" modified="2019-10-16" version="1">MDRNAAPEGSRWFERSEHHWRSQRPSKSPPPAGAHLDLRSLRDHRAFGSVFRRCAAARRPPATILNPFGILAPGTTVPTSQQPMDRGAAPEGSRWFERSEHHRKTQRSSNHRPRRGRTSICDPSGITARLGRYSGGAPLRDDLRLPFCIPSGSSHRTQLHQRPSSPRTAKRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITV1</accession>
    <name>A0A518ITV1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_25070</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="112" mass="11851" checksum="038FC123B01FCB1F" modified="2019-10-16" version="1">MQVTFKPVVGQRKRQRDGKAIDVPAKSPCGAAQLSILIDGKEIGLVLDRAKSPVSYLVRDLTDAEKAAVGNAIAARTGHAPTGGQQPPAEDEADDGFDDIDTDAMDTDVDFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITX8</accession>
    <name>A0A518ITX8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ribose transport system permease protein RbsC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rbsC_1</name>
        <name evidence="7" type="ORF">Mal33_25360</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="52"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="92"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="166"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="207"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="241"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="266"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV56544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="320" mass="32843" checksum="2B96F7AD60187BF5" modified="2019-10-16" version="1">MKNTAAYRSLIQYAGLLGVLALLVVVFASSSENFLQTRTFISIANQIPDLTLVAVGMTLVLVVGGIDLSVGSILAFSSAVLGALMVDWQWSLWASIPFCILAGAACGLFNGCVSVLAKIPSFIVTLGMLEIARGGTKLVTDSQTKYIGQAVESIGQPIAGLSLSPAFLMAIAAVVGGQLLLTRTVFGRYCVAIGTNEEAVRMSGVRPAPYAIGVFVISGVMCGLAGLTYASRLSTADPNAAIGLELSAIAACVIGGTSLMGGRGNVINSFLGVLIIAVLQTGLAQIGVSDPMKQIITGSVIVVAVLLDAIRSRWGNTAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUB2</accession>
    <name>A0A518IUB2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Amidophosphoribosyltransferase</fullName>
            <shortName evidence="4">ATase</shortName>
            <ecNumber evidence="4">2.4.2.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Glutamine phosphoribosylpyrophosphate amidotransferase</fullName>
            <shortName evidence="4">GPATase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4 9" type="primary">purF</name>
        <name evidence="9" type="ORF">Mal33_26790</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4 5">
            <text>5-phospho-beta-D-ribosylamine + diphosphate + L-glutamate = 5-phospho-alpha-D-ribose 1-diphosphate + H2O + L-glutamine</text>
            <dbReference type="Rhea" id="RHEA:14905"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58681"/>
            <dbReference type="EC" id="2.4.2.14"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4 7">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="4 7">Binds 1 [4Fe-4S] cluster per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 4 5">Purine metabolism; IMP biosynthesis via de novo pathway; N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-alpha-D-ribose 1-diphosphate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 4 5">In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.14" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00124"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004044">
        <property type="term" value="F:amidophosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009113">
        <property type="term" value="P:purine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01931">
        <property type="entry name" value="PurF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005854">
        <property type="entry name" value="PurF"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000485">
        <property type="entry name" value="Amd_phspho_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="4 5 9" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4 7" id="KW-0408">Iron</keyword>
    <keyword evidence="4 7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 4 5" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="8">
        <location>
            <begin position="8"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4 6">
        <location>
            <position position="8"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4 7">
        <location>
            <position position="278"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 7">
        <location>
            <position position="432"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 7">
        <location>
            <position position="492"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 7">
        <location>
            <position position="495"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR000485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000485-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000485-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV56681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="534" mass="59463" checksum="F8AED0510E6DF23A" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUI5</accession>
    <name>A0A518IUI5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lineage-specific thermal regulator protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_27530</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017799">
        <property type="entry name" value="Tscrpt_reg_PadR_acidobac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005149">
        <property type="entry name" value="Tscrpt_reg_PadR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03551">
        <property type="entry name" value="PadR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03433">
        <property type="entry name" value="padR_acidobact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PadR" evidence="2">
        <location>
            <begin position="31"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="123" mass="13849" checksum="06883EC0FF0915B2" modified="2019-10-16" version="1">MDIKRNEDIPLSDNNPQSNSRVLRGTLNMLIMRVVRDSPTHGYGIMKQIEAESGDVLKLEEGSLYPALHRLEKEGLLTSEWRQSESNRRAKFYHLTQTGSTALIAEIANWDVVSAAVNRVVQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVH3</accession>
    <name>A0A518IVH3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">N-acetylgalactosamine-N, N'-diacetylbacillosaminyl-diphospho-undecaprenol 4-alpha-N-acetylgalactosaminyltransferase</fullName>
            <ecNumber evidence="2">2.4.1.291</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">pglJ</name>
        <name evidence="2" type="ORF">Mal33_30830</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.4.1.291" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="1">
        <location>
            <begin position="17"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="385" mass="42430" checksum="DCF0BA4DC862F880" modified="2019-10-16" version="1">MARPYNVLLMAGSMDGGGSERQTLHLLRHLDRQRFAPHLFLCYRQGSLLDQIPDDVPVTAFWDQHRSPRLCVPGAIHRMQVRALRDLIIANKIDLIYDRTFHMSMLASPAARGLQCGRVATIVSPPDRDVPAAETRFVAVKRWLLRRSYRRADAIVTVSQAVADAAARYYGIDRRRFQTIHSPVDLQAIRNEAASANGDPAIDPVDVNIACVGRMTEEKGHRFLIDAIDSLRDHPVFDCLQLWMVGDGPLRSALTAQVRELKLDRQVHFVGQRASAVPIIAQCQLACVPSLYEGLPNVVLESMALGVPVIATTAGGSPELFGDRTFGDLVAPGDSAALASAILQFAEEPESAQEKSIQAKQHVCDKHSIEAVVPRIEQVMLSVIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVV0</accession>
    <name>A0A518IVV0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_32140</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024524">
        <property type="entry name" value="DUF3800"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12686">
        <property type="entry name" value="DUF3800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="298" mass="34935" checksum="89C92FA18F60E51D" modified="2019-10-16" version="1">MSWLLFMDESGHDHKQMPYEVRGGIALQDRKAWPFIRAVASLEENCFGVRLADFKKEFKGSKLLDKDRIKWAEQGPPQGDAERKRNARAFLSKGLQKQPQRRDEFTGYGQACLELARGIFRLLRDHDAKLFASVIPRGVKPPETFEAKEYLRKDHVFLLERFYHFVRKQQEQGLIVMDQVEEQNDIRFVRKLERYFVRTNKGAQRADWIVPAPFFSSSYLSIPIQVADVCIYCLNWGFRRPQWNMDAETRSRIEQDFSGWIKRLEFRQKTKNADGTLKNLFGIAFVQNPYGSGRDRSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IW19</accession>
    <name>A0A518IW19_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">50S ribosomal protein L24</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3 6" type="primary">rplX</name>
        <name evidence="6" type="ORF">Mal33_32800</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.</text>
    </comment>
    <comment type="function">
        <text evidence="3">One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3 4">Belongs to the universal ribosomal protein uL24 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06089">
        <property type="entry name" value="KOW_RPL26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01326_B">
        <property type="entry name" value="Ribosomal_L24_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005824">
        <property type="entry name" value="KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041988">
        <property type="entry name" value="KOW_RPL26/RPL24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_L2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003256">
        <property type="entry name" value="Ribosomal_L24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005825">
        <property type="entry name" value="Ribosomal_L24/26_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12903">
        <property type="entry name" value="PTHR12903"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00467">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17136">
        <property type="entry name" value="ribosomal_L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00739">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01079">
        <property type="entry name" value="rplX_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01108">
        <property type="entry name" value="RIBOSOMAL_L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 4 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="KOW" evidence="5">
        <location>
            <begin position="2"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00029550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV57276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="114" mass="12381" checksum="1AD8B74CE0D852B3" modified="2019-10-16" version="1">MLIKVDDNVKVIAGADKGTTGKVLKVDHKKNKVLVEGVARVWKHVRKSQKNPQGGRLNKEMPISISNVMIVCPQTGKPSRIGVRYLKDGTKERYAKVSGASLGAMSPPRPAYAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IW38</accession>
    <name>A0A518IW38_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5 7">50S ribosomal protein L3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 9" type="primary">rplC</name>
        <name evidence="9" type="ORF">Mal33_32910</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 7">One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 7">Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uL3 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01325_B">
        <property type="entry name" value="Ribosomal_L3_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000597">
        <property type="entry name" value="Ribosomal_L3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019927">
        <property type="entry name" value="Ribosomal_L3_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019926">
        <property type="entry name" value="Ribosomal_L3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11229">
        <property type="entry name" value="PTHR11229"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00297">
        <property type="entry name" value="Ribosomal_L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03625">
        <property type="entry name" value="L3_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00474">
        <property type="entry name" value="RIBOSOMAL_L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 7" id="KW-0699">rRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="57"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="58"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019301"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV57287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="228" mass="24726" checksum="4A9D53C340243B57" modified="2019-10-16" version="1">MSRGILGRKVGMTQLYSDDGTAITVTVLEAGPCNVLQVRTQERDGYQAVQLGFSDKPRRLASRSERGHVAKLDSKRQRDRSKSGAAPMAKADCEPQRFVREIRGESDLEVGAQVNVDAFAEVKAVDVTGTSKGRGFAGVMKRHNFSGQRATHGVKKVHRHAGGTGCSASPSRTFKGRRMAGHYGNAKHTKRNLQVVRVDAENNLIMVRGGVPGPAGGYVVIRETNMVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWN3</accession>
    <name>A0A518IWN3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cocaine esterase</fullName>
            <ecNumber evidence="3">3.1.1.84</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">cocE</name>
        <name evidence="3" type="ORF">Mal33_35080</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.1.84" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008239">
        <property type="term" value="F:dipeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005674">
        <property type="entry name" value="CocE/Ser_esterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000383">
        <property type="entry name" value="Xaa-Pro-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013736">
        <property type="entry name" value="Xaa-Pro_dipept_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02129">
        <property type="entry name" value="Peptidase_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08530">
        <property type="entry name" value="PepX_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00939">
        <property type="entry name" value="PepX_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00976">
        <property type="entry name" value="NonD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022146647" evidence="1">
        <location>
            <begin position="28"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="domain" description="PepX_C" evidence="2">
        <location>
            <begin position="336"/>
            <end position="617"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="624" mass="70103" checksum="19F9AED1CEB1A9CB" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWN5</accession>
    <name>A0A518IWN5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative permease YjgP/YjgQ family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Mal33_34850</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005495">
        <property type="entry name" value="LptG/LptF_permease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33529">
        <property type="entry name" value="PTHR33529"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03739">
        <property type="entry name" value="LptF_LptG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="53"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="97"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="316"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="341"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="375"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV57475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="398" mass="43797" checksum="A3A74E33E69186DC" modified="2019-10-16" version="1">MPTRLTRYILWEITKVFLVAIVSLTVLILLIVVARELLRQGLGPAALLQLLPLFLPLSLQFALPTTALFAVSAVYGRIAADGEIATIKAAGISPLTIMKPAFIFGLILSPIAVGLNDLAVSWGKPGVKHVLLHSLEEIVYRRLQAQRSYSSDKGFSIHVQDVKDHRLLWPTVTLHNSGSELPITVTASEGSLHLNAERETLMLRLVDSRIEGGGAFRSHFPGEIVPEIPLNKAFAKGDPSSSRPADLPLYLIGPEAIRSEKAMSIDRQRLAAQTGFALANGRWSDIVGSPGAQLRGAIGGGAHRLTRLHVEPWRRWSFGFSCFFFVLVGAPLAIMAKTADYWTSFGMVFLPILLFYFPIFIVGQDYAKNGELPPYSVWMANSVVAIVAVFMIKRVWRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWU3</accession>
    <name>A0A518IWU3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_35700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="125"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="158"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="223"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="296"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="327"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="358"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="381"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="429"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="475" mass="52066" checksum="1B8290212205F115" modified="2019-10-16" version="1">MSQILFHYQRPDPVTWVYLSSLLIIGLFFVFYRIWSLRNVDILLLLLLSPGLLMVHEGRQLRVAGETIVEATHSSQPPMPPEIAERIEVATPDELLGMADAATQTQPPEVLVAGVNVADVERWGFIWLLGVAGLICIRMILDPILVRRPLLDPNLSTGGLSFIGIAMFIFLMANVITSTAEIQAAQGPKPGPGYPLVNRLPAIATTPDAENADVAEPVRYAGVARALAIASQLAVALGVVFIGQFHFKNIRAGVGAAALYLLLPYTAQTTGRVDHVLPAALLIWAVFCYRRPILSGIFIGLAAGLVYYPLFLLPLWISFYWQRGLRRFLYGMGLTVAVLAALLFLGERDLILDRVQQMFGLWLPVTKGLAGIWGLGWNPIWRLPILVAFGVLSGFFAFWPGQKNLGTLMSCSAAVMAAAQFWHGYGGGLYVAWYLPLMLLTVFRPNLEDRIALKVIGNGRKRIGNHELAADSEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IX10</accession>
    <name>A0A518IX10_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ECF RNA polymerase sigma factor SigE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">sigE_4</name>
        <name evidence="4" type="ORF">Mal33_36420</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="2">
        <location>
            <begin position="31"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="3">
        <location>
            <begin position="153"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV57629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="202" mass="22567" checksum="2BAD1E1E1FC7A2D0" modified="2019-10-16" version="1">MHSSPPETRASLILRLPDAADVAAWDEVVAIYTPLIRRLAFAQGMQPADADDLVQEVFSAIARSVSQWLDRTDRGGFRAWLLTIARNAAVNHLTRRGTRTLATGDEDAAAMLAEVPAPASEVSSQFDQEYRREVFRWAAAQVKCQVAETTWSAFWMTQVEGMSVAETARRLEVSVGTIYVGRSRVMSRLKEVVKQHEVTQWC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IX11</accession>
    <name>A0A518IX11_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BatA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_36360</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024163">
        <property type="entry name" value="Aerotolerance_reg_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011933">
        <property type="entry name" value="Double_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07584">
        <property type="entry name" value="BatA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02226">
        <property type="entry name" value="two_anch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="BatA" evidence="2">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="772" mass="84296" checksum="427D0082B6668DE1" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IX27</accession>
    <name>A0A518IX27_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_36490</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="182" mass="19863" checksum="2D57BEF98DF4195C" modified="2019-10-16" version="1">MSAFVRQSIWPIPKRSRRFSCSHSAPRRPIGIDSNAADATALKQIRPSQTQVRTTGNVYLPSLRITARCGDTECDGQSLHCHVISRADRLAVSEPLSRGNVSWWSTAVARRVGTLPVPKLMSVALRKVSVARSPCRFFAGLAFGAETNFAQHTAGGLQVIALDFQLVLFDRAASAAPRLQFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IX44</accession>
    <name>A0A518IX44_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_36700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021720708" evidence="1">
        <location>
            <begin position="22"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="141" mass="14467" checksum="16DDB9BD68B41D94" modified="2019-10-16" version="1" precursor="true">MKQLLVVAGLLCLLSSTGGCAKAWTRGGCSSASCQCGQGQCNNDGCQSCQGQGQCSSGQCGNGARGMASCCRGGVSTGCRPAPLSWQQGGTDYGHNLTYPNVKNGQMQQNPGPPAASTAYPYYTTRGPRDFLNANPPSIGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IX47</accession>
    <name>A0A518IX47_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Nitrogen fixation protein VnfA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">vnfA_2</name>
        <name evidence="8" type="ORF">Mal33_36730</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00060">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002197">
        <property type="entry name" value="HTH_Fis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002078">
        <property type="entry name" value="Sigma_54_int"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025662">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025943">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025944">
        <property type="entry name" value="Sigma_54_int_dom_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032030">
        <property type="entry name" value="YscD_cytoplasmic_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02954">
        <property type="entry name" value="HTH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00158">
        <property type="entry name" value="Sigma54_activat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16697">
        <property type="entry name" value="Yop-YscD_cpl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01590">
        <property type="entry name" value="HTHFIS"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SSF49879"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00675">
        <property type="entry name" value="SIGMA54_INTERACT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00676">
        <property type="entry name" value="SIGMA54_INTERACT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SIGMA54_INTERACT_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50045">
        <property type="entry name" value="SIGMA54_INTERACT_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="FHA" evidence="6">
        <location>
            <begin position="25"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma-54 factor interaction" evidence="7">
        <location>
            <begin position="306"/>
            <end position="535"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV57660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="606" mass="68091" checksum="739D5BFB1CBDCE5E" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IX99</accession>
    <name>A0A518IX99_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Inositol 2-dehydrogenase</fullName>
            <ecNumber evidence="8">1.1.1.18</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">iolG_11</name>
        <name evidence="8" type="ORF">Mal33_37260</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.18" evidence="8"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016798">
        <property type="term" value="F:hydrolase activity, acting on glycosyl bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050112">
        <property type="term" value="F:inositol 2-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008152">
        <property type="term" value="P:metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043906">
        <property type="entry name" value="Gfo/Idh/MocA_OxRdtase_bact_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019546">
        <property type="entry name" value="TAT_signal_bac_arc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19051">
        <property type="entry name" value="GFO_IDH_MocA_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01409">
        <property type="entry name" value="TAT_signal_seq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0520">NAD</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GFO_IDH_MocA" evidence="6">
        <location>
            <begin position="45"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="GFO_IDH_MocA_C2" evidence="7">
        <location>
            <begin position="203"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF19051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV57713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="452" mass="50259" checksum="CCA84FB0BEE0884C" modified="2019-10-16" version="1">MSNQNRRDFLRTSAVAGASVSVPYFFSRSQTLADETKAKNDRIPIGLIGAGGMGMGNMRAAADYLDVVAIADADKSRQEAANKKLSNGKADVYDDYRKILERDDIKIVHVATPDHWHTKPVIEAMLAGKDIYCEKPLTLTIDEGKQIRKVQRETGRIVQVGTQQRSTFPLFTKAIAMVQQGRLGKILRVQAAIGGAPTSPAIPVAETPAGLDWERWLGPAPKTDYRFLADDKRGKTNGHYEFRWWYEYSGGKLTDWGAHHVDIATWALSVNGQPTSPVSIGGTASHPVEYKDGVPQQNDRYNTATAFNFVAKYADGTEMVIRNDTDNGVLIEGEKGRIFVNRRKLVGAPVEELKDNPLPEDAIQKAYKGLPMEENERKAHWANFLNCTQTRDEPISDVHSHMKMLNVCHLAGISARLGRTLNWDGENEQITGDSEANAMLARPYREGYEIEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXI4</accession>
    <name>A0A518IXI4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_38100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011465">
        <property type="entry name" value="DUF1571"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07608">
        <property type="entry name" value="DUF1571"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021997841" evidence="1">
        <location>
            <begin position="26"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="291" mass="33148" checksum="6E9EEFFB446351A7" modified="2019-10-16" version="1" precursor="true">MNHSRRQILSMLAAATAGATSSAFAQAPQSKFQEPVFRIAANNSLTPATHPLDEALRIAHEGLQEIRTNISDYTATLVKRELVGNTVGEYEYMFIKVRNRRVEDGRVVVPFSVYLAFLKPATVKGREVIYVEQQNDNKMVAHEGGFKGRFLPTVWLKPEGAFAMRGQKYPLTEIGIENLVLKLIERGEQDRQHKDVKVEFRKNAKINGRDCSVIQVTHPEYRPEFDFSLGQIFIDDQMNIPVRYVAYGWPKTPGQKPEINEEYTYLNVKLNVGLTDADFDPNNPNYSFYSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXM0</accession>
    <name>A0A518IXM0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Leucine Rich repeats (2 copies)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_38450</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="17"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="255" mass="28298" checksum="65931F21ACBA4342" modified="2019-10-16" version="1">MVQAYNPTRFSIPTWPAWAQMVVACFAGALAGGYISAKVAVSRSDESIRQQMEMRAIDRFVSLGGEVLRDGDKLSPVGMPALRGLGFYTIRSASDVRQAILYGGTLPGITQLHFAPFGVNRVGAGVTDGDVLRFANRNFKNVEYLDLSNCRIQDASVIQPMVDLKRLRLGNNPLTKNGVESLNLLDSVVELWIGWPDRTISPDSMYRSAELRKTLVKALTEMDKLQKVHLYDDIQLTQSEKAQLGELELVKAYMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXR1</accession>
    <name>A0A518IXR1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ATP-dependent protease subunit HslV</fullName>
            <ecNumber evidence="5">3.4.25.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 6" type="primary">hslV</name>
        <name evidence="6" type="ORF">Mal33_38720</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP-dependent cleavage of peptide bonds with broad specificity.</text>
            <dbReference type="EC" id="3.4.25.2"/>
        </reaction>
    </comment>
    <comment type="activity regulation">
        <text evidence="5">Allosterically activated by HslU binding.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the peptidase T1B family. HslV subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.4.25.2" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009376">
        <property type="term" value="C:HslUV protease complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005839">
        <property type="term" value="C:proteasome core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004298">
        <property type="term" value="F:threonine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051603">
        <property type="term" value="P:proteolysis involved in protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00248">
        <property type="entry name" value="HslV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022281">
        <property type="entry name" value="ATP-dep_Prtase_HsIV_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023333">
        <property type="entry name" value="Proteasome_suB-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194">
        <property type="entry name" value="PTHR32194"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039093">
        <property type="entry name" value="HslV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03692">
        <property type="entry name" value="ATP_dep_HslV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51476">
        <property type="entry name" value="PROTEASOME_BETA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5 6" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0915">Sodium</keyword>
    <keyword evidence="5" id="KW-0888">Threonine protease</keyword>
    <feature type="active site" evidence="5">
        <location>
            <position position="6"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV57857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="180" mass="19246" checksum="E1C3D7230F068417" modified="2019-10-16" version="1">MELHATTILSVRRGNKVAMGGDGQVTLGTTVMKSDACKVRRLNEGRVLCGFAGGAADAFALLERFEEKMRDYPANVPRAATELAKDWRMDRALRRLEALLAVADGKHSLLISGTGDVIQPTDGVIGIGSGGHYAIAAARALLAHSDLSAAEIVRRSMEIAADIDIYTNRNIVVEELEAVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXR2</accession>
    <name>A0A518IXR2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">MG2 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_38970</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004866">
        <property type="term" value="F:endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041246">
        <property type="entry name" value="Bact_MG10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008969">
        <property type="entry name" value="CarboxyPept-like_regulatory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001599">
        <property type="entry name" value="Macroglobln_a2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002890">
        <property type="entry name" value="MG2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008930">
        <property type="entry name" value="Terpenoid_cyclase/PrenylTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00207">
        <property type="entry name" value="A2M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17973">
        <property type="entry name" value="bMG10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01835">
        <property type="entry name" value="MG2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01360">
        <property type="entry name" value="A2M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48239">
        <property type="entry name" value="SSF48239"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49464">
        <property type="entry name" value="SSF49464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021829649" evidence="3">
        <location>
            <begin position="22"/>
            <end position="2002"/>
        </location>
    </feature>
    <feature type="domain" description="A2M" evidence="4">
        <location>
            <begin position="1245"/>
            <end position="1335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="858"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1210"/>
            <end position="1229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV57882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="2002" mass="224063" checksum="66E2DEACA777483E" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXS2</accession>
    <name>A0A518IXS2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_38980</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022175190" evidence="1">
        <location>
            <begin position="22"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="356" mass="39743" checksum="A36EC1060F4C2621" modified="2019-10-16" version="1" precursor="true">MTKSFYTSLLSLALLAASTTAALGQSSPNALTFNDPNPQRYQLKARASELDPRVQAHSEIDFLIETKDGKPADFQQAAVDTRVAPKGKLVIWLMGHNQGLFDRWNSYGLHAIRVHYANKWFSICCRENPVGEECRGNIRLEAATGEDFSDDVDIPKPDGMMERALKFVQWLAKENPQGGWDYFLTEDGNGLRWEDVIMSGSSHGSTTAARFAKHQKVSRVVALCGPRDNYQTWQSLPSATPENRYFGFSHVLDGGWTADHYCRSWEMLGMNKFGPIVNVDKIGPPYQNTRRLITDFDVDGNARRAHSSVQPGGSAGKDADGKYIHEAVWKYLYTHPVDVVGEATPPDASCIKNQRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IY34</accession>
    <name>A0A518IY34_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Peptidyl-dipeptidase dcp</fullName>
            <ecNumber evidence="10">3.4.15.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">dcp</name>
        <name evidence="10" type="ORF">Mal33_40120</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 1 zinc ion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the peptidase M3 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.15.5" evidence="10"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06456">
        <property type="entry name" value="M3A_DCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034005">
        <property type="entry name" value="M3A_DCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024077">
        <property type="entry name" value="Neurolysin/TOP_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045090">
        <property type="entry name" value="Pept_M3A_M3B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001567">
        <property type="entry name" value="Pept_M3A_M3B_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43660">
        <property type="entry name" value="PTHR43660"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01432">
        <property type="entry name" value="Peptidase_M3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="4 7 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2 7" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="5 7" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021796290" evidence="8">
        <location>
            <begin position="27"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M3" evidence="9">
        <location>
            <begin position="261"/>
            <end position="709"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV57996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="713" mass="80684" checksum="1B4A13FC3BD12546" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYK2</accession>
    <name>A0A518IYK2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ECF RNA polymerase sigma-E factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpoE_6</name>
        <name evidence="4" type="ORF">Mal33_41830</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014326">
        <property type="entry name" value="RNA_pol_sigma-70_Plancto"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02984">
        <property type="entry name" value="Sig-70_plancto1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="2">
        <location>
            <begin position="24"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="3">
        <location>
            <begin position="141"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV58166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="202" mass="22676" checksum="DD74F9A8500A197B" modified="2019-10-16" version="1">MSQSTTQFLLDRAREGDADAFGELLEQYRSYLWILAHRYLDDRLRQRIDPADLVQITFMEAQRDLPAFRGQEPAAFVVWIRNILRNNLASAVARHVITQKRSVAHEVRLANDSSRGPGLAGQLAGSTTSPSQQIMRAETSQALLDALDQLPEMQAAAIKLRYMEGLNMKEISEAVGKTEMAVGGLLKRGLKRLREILLDESQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYK3</accession>
    <name>A0A518IYK3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_41790</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="56" mass="6191" checksum="35CB89DA67C16584" modified="2019-10-16" version="1">MAKELCKLKKSLRGEIGMYVRLISEPTHVCLKCGRAANDKKLLCKPQSIASAMQKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYR7</accession>
    <name>A0A518IYR7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Diapolycopene oxygenase</fullName>
            <ecNumber evidence="5">1.14.99.44</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">crtP</name>
        <name evidence="5" type="ORF">Mal33_42540</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1 3">Carotenoid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the carotenoid/retinoid oxidoreductase family.</text>
    </comment>
    <dbReference type="EC" id="1.14.99.44" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00392"/>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016117">
        <property type="term" value="P:carotenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014105">
        <property type="entry name" value="Carotenoid/retinoid_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02734">
        <property type="entry name" value="crtI_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0125">Carotenoid biosynthesis</keyword>
    <keyword evidence="3 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amino_oxidase" evidence="4">
        <location>
            <begin position="18"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV58236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="505" mass="55721" checksum="EC63949C23175151" modified="2019-10-16" version="1">MHKGTEVSQRVVVVGGGLAGLAAACTAAARGHRVILLDKNEWVGGKAAVLESGGFRFDMGPTILTLPSVLKRIFSEAGRDLRDYMELVPLDPQWRCFFDGGGVLDLVSDLQQMQQRLDEFTGGPESGEGYGRFMEVSKQLHEVSEKFFFWRSIGSIRDTMDASGAFSPSVLKDVMSLRMGKSVSKVVRQHVPDDRAAQMIDHFTQYVGSSPEASPAVLCGIAHMQTDEGIWYPIGGTRAVVEGLSRLAIELGVDIRVGVDVARINVESRRATGVQTTTGEVIPADAVISNCDSVRTYRELLKGCPHARLKLRDPEPACSGVVLYLGLDRRYEQLLHHNFVFSRDPEEEFDYIYRRGQLAPEPTCYVCAPAVTEPQVAPEGGEALYVLVHTPYLRPGQDWSVMLPDYRRRIIEKLQETAELDDLESHIKFEQVLTPQDIHNRYRVLNGAIYGLASHGKFTGAFKPANRRKDIRGLYLAGGAAHPGPGMPMVMMSGWIAADCLDQDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYR8</accession>
    <name>A0A518IYR8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Adaptive-response sensory-kinase SasA</fullName>
            <ecNumber evidence="3">2.7.13.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">sasA</name>
        <name evidence="3" type="ORF">Mal33_42350</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.13.3" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="2">
        <location>
            <begin position="35"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="479" mass="53066" checksum="2B97D4A7610CD532" modified="2019-10-16" version="1">MPKLSMFQTGLTNNSITPKEDPRVALDFAGHLLTDTAHDLRSPLAAARELTQLVADGVEGPVSEEQKEHLQAVVARCNDMQRLIDDMLHFECVRTGSPRIAKNWLPASGLPAQVQPLIESSRRSRGVGLQWIGFENKLPPMFADGDKIKRLLVNLIDNAIRVTPESGTITVRTELARTGDRIRLSVEDTGAGIAPQQWSQLAKRGVSQLDGHGLGLSICRQIAALHFGQLEVSSEPGKGARFSIELPTGGPAAVVDSFARWRETISPAAASEASAAHRAGERIRPVRRRVDLAANRQTLPVETAPPRYRRSVAMVGVTVSELLPTEPMRDLDRFLQSHCEIHELVYQLQEDQWVMLLDSNIGEAEQRIAAIDRARSQTGDMLLERCQLQWSSPLALAVGRPADRSKLQEAFVTGKLGVHRSLSRRSKEPSQSEDVAGSQPLLSAVAQQRLESEVRWLTQKFRQRQSCLRRQVEAIRPKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYT5</accession>
    <name>A0A518IYT5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GTPase HflX</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">GTP-binding protein HflX</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 11" type="primary">hflX</name>
        <name evidence="11" type="ORF">Mal33_42670</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5">Monomer. Associates with the 50S ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="5">May associate with membranes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01878">
        <property type="entry name" value="HflX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00900">
        <property type="entry name" value="GTPase_HflX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030394">
        <property type="entry name" value="G_HFLX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032305">
        <property type="entry name" value="GTP-bd_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016496">
        <property type="entry name" value="GTPase_HflX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025121">
        <property type="entry name" value="GTPase_HflX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042108">
        <property type="entry name" value="GTPase_HflX_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10229">
        <property type="entry name" value="PTHR10229"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16360">
        <property type="entry name" value="GTP-bdg_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13167">
        <property type="entry name" value="GTP-bdg_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006809">
        <property type="entry name" value="GTP-binding_hflX_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03156">
        <property type="entry name" value="GTP_HflX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51705">
        <property type="entry name" value="G_HFLX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5 6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hflx-type G" evidence="10">
        <location>
            <begin position="201"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="422"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="169"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="430"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="207"/>
            <end position="214"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="214"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="232"/>
            <end position="236"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="234"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="254"/>
            <end position="257"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="320"/>
            <end position="323"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="345"/>
            <end position="347"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR006809-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR006809-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QDV58249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="451" mass="50517" checksum="3E8668433E4B8005" modified="2019-10-16" version="1">MRDEQRIESLASERSVLVRLLLPSHKSEVDPLAELTGLATTAGTDVVGGLVQRRDKPDQKTFIGKGKVNELKGLIDQFEADVVIFDNDLYPGQTRNLEQALHTKVIDRTELILDIFASNAQTYEARLSVELAQLEYSLPRLKRMWTHLSRQSMGVGMRGPGETQLEVDRRLVETRIHELRESLQKVERRRERQVAARSDNATVSLVGYTNAGKSTLMNALTGADVEAADKLFATLDTRTRRWQLIGWGPVLLSDTVGFIRDLPHRLIASFKATLEEARQAELLLHVADASNPAVLDQIHAVYKVLEEIGIEEKDTLLVLNKIDAIESRQLLERIVDRYPNALTCSAKAGIGLKELSLAVGDALSREFLDLHVDIDPANGKLQAYLSAKGEVLSREMTSEVITVHCRMPRKTLGEIRRTALQVRSGDSRPLPPEPTEDDFRPRKKNETIESE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYT7</accession>
    <name>A0A518IYT7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Phosphate regulon transcriptional regulatory protein PhoB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">phoB_1</name>
        <name evidence="6" type="ORF">Mal33_42550</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="5"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="133"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="133"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV58237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="235" mass="26360" checksum="93A5F26B52C8CF9A" modified="2019-10-16" version="1">MPNIKVLVVEDDLSVAEVLVYNLKKEGFEVSRALDGRDALNQARLKLPDLVILDVMLPSLNGLEVCRTLRASEDTKNISILMLTAKSEDSDQIAGFSIGADDYVCKPFSVAVLLQRVKALLRRREQAAAIKNQDIVSYKSVSVDRRRYKAAVGEEPLDLTRSEFRLLDTLIRQPGRVFDRAELIDAALGEDTMVLERTIDVHIRALRKKLGSYADVIETVRGVGYRFSEAMHEEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ05</accession>
    <name>A0A518IZ05_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_43440</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="72" mass="8352" checksum="F6EA3B9CBC3B2F6E" modified="2019-10-16" version="1">MPRYWWLISKQFNCVDIATLFGRTRAAGYARAETRKYDTTCLSQQSWDHLARLAIGERLVAVGAMERQLFVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ06</accession>
    <name>A0A518IZ06_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">FecR protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_43290</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="FecR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012373">
        <property type="entry name" value="Ferrdict_sens_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006558">
        <property type="entry name" value="LamG-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30273">
        <property type="entry name" value="PTHR30273"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04773">
        <property type="entry name" value="FecR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00560">
        <property type="entry name" value="LamGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="100"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="LamGL" evidence="3">
        <location>
            <begin position="414"/>
            <end position="558"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV58311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="571" mass="63614" checksum="C8677D2A82390506" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ09</accession>
    <name>A0A518IZ09_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">pknB_20</name>
        <name evidence="9" type="ORF">Mal33_43360</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="56"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="86"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="118"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="147"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="173"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="212"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="249"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="278"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV58318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="552" mass="60714" checksum="4FBC1B361BDABAF3" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ52</accession>
    <name>A0A518IZ52_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphopantothenoylcysteine decarboxylase</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">Mal33_43850</name>
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    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1950">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036551">
        <property type="entry name" value="Flavin_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003382">
        <property type="entry name" value="Flavoprotein"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02441">
        <property type="entry name" value="Flavoprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52507">
        <property type="entry name" value="SSF52507"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavoprotein" evidence="1">
        <location>
            <begin position="13"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="189" mass="19876" checksum="C85453D8FCA756A5" modified="2019-10-16" version="1">MNQASSTTNTTPRVVVGIGGGIAAFKAASLVSQLVQGGIEVRVVMTAASEQFIGTNTLAALSGHPVATTGYAPTIWPLGPHIELSRDCDLLCIAPATADLIGKFAHGIADNLLTTLYLQATCPVLIAPAMSDQMWSKPAVQRNIRQLAEDGVQQIGPEEGWLSCRKRGAGRMSEPDAIAQKVRDLISQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ82</accession>
    <name>A0A518IZ82_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_44120</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011521">
        <property type="entry name" value="YTV"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07639">
        <property type="entry name" value="YTV"/>
        <property type="match status" value="15"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021884016" evidence="1">
        <location>
            <begin position="22"/>
            <end position="546"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="546" mass="63455" checksum="D455EF0DC74D2A3C" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ96</accession>
    <name>A0A518IZ96_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">UDP-3-O-acylglucosamine N-acyltransferase</fullName>
            <ecNumber evidence="5">2.3.1.191</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">lpxD</name>
        <name evidence="7" type="ORF">Mal33_44360</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a (3R)-hydroxyacyl-[ACP] + a UDP-3-O-[(3R)-3-hydroxyacyl]-alpha-D-glucosamine = a UDP-2-N,3-O-bis[(3R)-3-hydroxyacyl]-alpha-D-glucosamine + H(+) + holo-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:53836"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:9945"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78827"/>
            <dbReference type="ChEBI" id="CHEBI:137740"/>
            <dbReference type="ChEBI" id="CHEBI:137748"/>
            <dbReference type="EC" id="2.3.1.191"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Bacterial outer membrane biogenesis; LPS lipid A biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homotrimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the transferase hexapeptide repeat family. LpxD subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.191" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00973"/>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016410">
        <property type="term" value="F:N-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03352">
        <property type="entry name" value="LbH_LpxD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00523">
        <property type="entry name" value="LpxD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007691">
        <property type="entry name" value="LpxD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020573">
        <property type="entry name" value="UDP_GlcNAc_AcTrfase_non-rep"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43378">
        <property type="entry name" value="PTHR43378"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04613">
        <property type="entry name" value="LpxD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01853">
        <property type="entry name" value="lipid_A_lpxD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2 5" id="KW-0441">Lipid A biosynthesis</keyword>
    <keyword evidence="1 5" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="4 5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 5 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="LpxD" evidence="6">
        <location>
            <begin position="23"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV58418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="350" mass="36776" checksum="69D07EA40F6A7366" modified="2019-10-16" version="1">MKPIAIRQLANELAATVIGDDSLQITGANPIGEASASEITLLDNVERRSDLESTAASAVVVASELENCPLVQLIVPDVHAAFMEIVAKFRPSQIVAPAGISPHAVVDPSAQIADDATIGPGCVIGANVTIGPRCNLVSGVTVMSGCTLGSEVNLMPGVLLYENTILEDRVWIHGGSILGAFGFGYRQSEGKHIRTGQLGYVHVESDVEIGAAVTIDRGTYGATRIGTGTKIDNQVQIAHNVQVGRHNLICSQVGIAGSSSTGDYVVLAGQVGLKDHIKLGDGVIVGAQGGVMADCEAGNVYLGSPATKQKEQMQIFAMWRRLPEMRRQIKTLEKQLSKMQDNSGSQTKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZL6</accession>
    <name>A0A518IZL6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF2063 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_45590</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.690">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018640">
        <property type="entry name" value="DUF2063"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044922">
        <property type="entry name" value="DUF2063_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09836">
        <property type="entry name" value="DUF2063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2063" evidence="1">
        <location>
            <begin position="11"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="303" mass="33657" checksum="51419C5B4F97DF72" modified="2019-10-16" version="1">MESQSRGLQSVQQWMQAVITHPDGVQSGSQSETARDALGEAAGASLEDLILPSQRLDSQQRIEVYANAYYARLLECLSEEFPALVKLLGEETFNAFAVEYLQFFPSQSYTLADLGANFHHFLSQYRDAAQEDADSDSLERSWSDLMIDLAQLERTYSEVFSGPGIEQMETLRGDALATVPPQSMGSICLTPAPCLRLLQLNSAAHDYAIAVRKQADLEGAFPEMRPTYLAITRIRYVVRTIELEPGEFEILQQLCEGVSLEAAIANVAALDSLDDTALAQRLLAWFQKWATDQMFVDFHVASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZQ2</accession>
    <name>A0A518IZQ2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative sugar kinase YdjH</fullName>
            <ecNumber evidence="4">2.7.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ydjH</name>
        <name evidence="4" type="ORF">Mal33_45920</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.1.-" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002173">
        <property type="entry name" value="Carboh/pur_kinase_PfkB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00584">
        <property type="entry name" value="PFKB_KINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PfkB" evidence="3">
        <location>
            <begin position="7"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV58569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="319" mass="33850" checksum="4103D3D4C5D445E2" modified="2019-10-16" version="1">MEKQWDCVVCGSCTADILVRPMSLDEPVGAGRMHRVEPIGLTTGGLASNAGIAMSRLGLGVAMLSYTGNDAWNTIMRENYKKERVDTSRLLRHAELPSSTTVVMIDAEGQRSFAHHQGAPRMIDRQMILDNLDLIAASRMFLIGYYSLLPHLQNDLPEIFAKIRETGCMTAMDAAGSGGDLQPLDQILPHLDVYVPSHGEAEHQTGQSDPRAIIDVYRSCGAVGLLGVKLGSDGALLQEPDGTFWQIAPVEPPGEIVDTTGAGDSFYAGLIAGLLRGMTPQDAGRLAAANGAICVTASGATTAITDLKTTMNLAGLETG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZU9</accession>
    <name>A0A518IZU9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">pknB_21</name>
        <name evidence="6" type="ORF">Mal33_46430</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="5">
        <location>
            <begin position="89"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="469"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="503"/>
            <end position="536"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV58619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="758" mass="84057" checksum="08B8914A1206DEB1" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J022</accession>
    <name>A0A518J022_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_47170</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008930">
        <property type="entry name" value="Terpenoid_cyclase/PrenylTrfase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48239">
        <property type="entry name" value="SSF48239"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="87"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="530" mass="58221" checksum="0C77D8FD71924AD0" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J047</accession>
    <name>A0A518J047_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_47330</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="244" mass="27778" checksum="FFC4C25A647D9DE8" modified="2019-10-16" version="1">MNIENVVTDAKELCYAVAPAELSGSPLWVVPQTNLPPMLGRHTVCYGYTSPSLDMHLHHCFADWEGIRGPVIVIGNLNIERDFPERTYNKMLGTTLHELAHILERPSLFQPRGYNQQYIRAEAIRVAEAVSREEEGDGTTPPWTTHESRFMRIAYHLYFRARSLGYDVRADEVYSPERYGMSPAAKYASEIKAEASTLCAATFRQICSLTPPPAFKAVYEADQRSWINSQSQRQRMNNEFDITT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0B8</accession>
    <name>A0A518J0B8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_48120</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
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    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="532"/>
            <end position="641"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="641" mass="73942" checksum="780B8C7B16DED351" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0K4</accession>
    <name>A0A518J0K4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_48870</name>
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    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
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            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Rosistilla</taxon>
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="entry name" value="DUF1501"/>
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        <property type="entry name" value="TAT_signal"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="378"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="379"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="484" mass="53127" checksum="F73915014EC63525" modified="2019-10-16" version="1">MSNPKTKPSEMHCSGPRNFGPGSRRSFMRLGLAGFASMSLPGIMRLQAASPLPTQTADGKERKRTAVIMVWQPGGNSHIDTYDPKPLSGSEYRGPFNTIPTKVPGMRFTELLPRQAAIADKFTVLRSMYQGAGGHPAGSMQLLSGDSDTRDKPKPRLPDWMSVANYLRSKEGPRTNPLPAYVGVNPPLQYNGPAYLGDAYSPFSVTGDPNSPKFVVPNIGLTDANQVARLGRRTTLRQQLDTLERSFDHFGEMGALDDFETQAMTLLTNPKTKDAFDLTQEDDRTRDRYGRNAWGQQLLLARRLVEAGVEVLTSSLRGPLCGRVNNWDDHAVNHHIFDALRFRADAYDQAVTALIEDIYERGLDERVMVVVTGEFGRTPKISHQPSTGAGNASAPSGTKQPGRDHWPRAFSNIWAGGGIETGRFIGATDKRGEDVVERRCGPGDFLATIYHHLGIDSKSVFIEDFNGRPTPIVDHGAPIPELMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0K9</accession>
    <name>A0A518J0K9_9BACT</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_49110</name>
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    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
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    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
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        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021745996" evidence="1">
        <location>
            <begin position="23"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="303" mass="33437" checksum="0D3F71FEC44DEDE7" modified="2019-10-16" version="1" precursor="true">MDVRFLTWVSLSVALLPAITFAQPYDVAVRPISVLRPGTIVDQGPPEGWTHLIVKSFPKVASGDVDKIPERDSQLASLMFTALAARTQQLPDGSWQLTEVATGAGTSVRGRDMIVSSDTQQQLGADLGFFARMVLKEFDAKQTQVQYKAISRHFFIVDTIGAFRWENQNRLLPLRYALVLNPQTGHLDTFCWLMDADSSGVSTTAVGSIHWLPQSLVFAPQLHVDYSKYNFLGIPSDTAFCSTNIPPGQVTMNIPADATRVLAQPKLSVQDAASLHGWFNQISTSMRPHYDRAALSKTTTTQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0V7</accession>
    <name>A0A518J0V7_9BACT</name>
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    <gene>
        <name evidence="2" type="primary">namA_2</name>
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        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.6.99.1" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="F:NADPH dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
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        <property type="term" value="F:pentaerythritol trinitrate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
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        <property type="entry name" value="OYE_YqiM_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="YqjM-like"/>
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    </dbReference>
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        <location>
            <begin position="2"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="QDV58968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
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    </evidence>
    <sequence length="358" mass="39154" checksum="764C656E24B23D48" modified="2019-10-16" version="1">MKLFEKYSLKDVTMRNRIVVSPMCQYSSVDGAPNDWHLVHLGSRAVGGAGMVIVEAAAVSPEGRISPGDAGIYSDDHVEPYAKINRFMKQQGAVPGIQIAHAGRKASASRPWEGDEHIGSDQGGWDTIAPSAEAFGGSLPKVPQAMSLVDIARVKMNFVQAAVRALEAGFECLQVHFAHGYLAHEFYSPLSNKRTDQYGGSFENRTRFMLETFEAVREVWPERLPLMVRLSVTDWIDGGVTVEESIELTRQLKASGLDLLDVSHGFVTADISTIPWGPGMMLPIAGRIREEVGIPTTASWLITEPEQAAAAVDDGQVDVVSLAREMLRDPYWPFHAAKQLGVADAEQILPIQYARAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0Z1</accession>
    <name>A0A518J0Z1_9BACT</name>
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            <fullName evidence="1">DUF262 domain-containing protein</fullName>
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    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004919">
        <property type="entry name" value="DUF262"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03235">
        <property type="entry name" value="DUF262"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF262" evidence="1">
        <location>
            <begin position="3"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="280" mass="31759" checksum="F97183CC98EFB683" modified="2019-10-16" version="1">MAANSEDSWEIVDGLQRLTAVAKFCGNESQRAIVKQPDILRLSSLKKLEAFNGKTFADLPLSLQSGFMKRAFKVVTLSDKSDIIVRFDLFERLNRGGLKLSKQEIRHCVIRGEFAGFLEEMGQDSAFRSVVRLKSNQEADATREECVLRFFAFLYDRESFEHLVDDFLTEYMEKANNDFDYITAAAEFRQTFEKLAEVFPNGIMRHGKKKSKTSLILFEGVSVGAALAIRESGRLSERGLDWLANEELKRNTTGATNNKPAVNGRIDFCRDMFLGKPEPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0Z8</accession>
    <name>A0A518J0Z8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_50410</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="176" mass="20549" checksum="81C8BA03F77060F4" modified="2019-10-16" version="1">MGCDIHSHLEYRHPKHGIEPVIANFFTFGRDYNLFATLAGVRNYDERPVFCSPRGLPEDVSEYIHQQFYTEIIPDNAADWRKNVMHEWCYEAQAKQYVEQHNSHIRGYNDSHRYVSNPDWHNASYLTRAEIIDSSAVSNYKLSSAPPEFQMVLDFMDSIDRRFGSGASRIVFCFDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J132</accession>
    <name>A0A518J132_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_50400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="138"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="162"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV59015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="182" mass="20395" checksum="C2428B7C94C9838B" modified="2019-10-16" version="1">MVKCKDCGWLSIQDQKHVWHSADSRFREKGVSSGDFIDTPLCSEDMLESCGNGSSKATILATIGKDRECSGFIPVVNGRELKGYKEMQAVEVLRLETRQDRAEDKAEMLKYRMEDKAEREAERAASEARYKKERNRTYVAIVLAAVLTFLASYSMYRIESTAKDQASPATPTHESDADAVSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1A9</accession>
    <name>A0A518J1A9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_51520</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011453">
        <property type="entry name" value="DUF1559"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07596">
        <property type="entry name" value="SBP_bac_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="14"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="309" mass="33610" checksum="A63D8E708F41B349" modified="2019-10-16" version="1">MFSSYRTPRPTRGFTLVELLVVIAIIGVLVGLLLPAVQQAREAARRFSCKNNLKQLALGLHNYESTFGLLAPGYLHKFDAIGAGANQMGAAWGCLILPQIEQQNLHDQFDFNIPMFDVRNLLPREQSLPVFLCPSDPFSEDNFVVRDESASPIEQYAAGSYAANWGPSTAAVNLDDTPLQSQGVFYRNSATRFRDITDGLSNTLFLGERTNGPLPGTTVGGHAFFETAWSAAVREITELTDDHGHMVLFETQFRPNQIGTDDKGLSAPHAGIGQFAIADGSVRSINETIEEAVYNALGTRGGGEVVGEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1C2</accession>
    <name>A0A518J1C2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">6-phosphogluconolactonase</fullName>
            <ecNumber evidence="1">3.1.1.31</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">pgl_4</name>
        <name evidence="1" type="ORF">Mal33_51580</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.1.31" evidence="1"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017057">
        <property type="term" value="F:6-phosphogluconolactonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011048">
        <property type="entry name" value="Haem_d1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019405">
        <property type="entry name" value="Lactonase_7-beta_prop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10282">
        <property type="entry name" value="Lactonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51004">
        <property type="entry name" value="SSF51004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="400" mass="42889" checksum="F8072E232110CD05" modified="2019-10-16" version="1">MAKGLRAAGPAATERPLMAYVGTFSSPLKDMLPTQVDLPPGNGRGIHTFRVDRKTGALTAAGDYPLGTSPSCLVVNEAGTRLYSANETDRVGADKQGTVSAFAIDPSDGQLKLLNTVPAGGAGPTYVSIHPTGRFLLVANYFGGSVSVMPILEDGRLGEASDTKVDEGPIGPTKATHAPEGSFAISGHDRTHAHMIEADPSGRFVLHVDLGLDKIYVWKFDAKTGTLHANDPAGVDLPPGDGPRHFHFHPEGRWFYSIQEEGSTIALFDYDSEAGSLKPRQTISTLPPSFTGSNFCSEILVSADGRFVYAGNRLHDSIGIFAIGDDGTLSYVGEEWTRGNYPRSFNFDPTGNFLYCCNQRADHVTVFKVDKATGKLDFTDQYVPVGNPSMITFLDLAKVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1E5</accession>
    <name>A0A518J1E5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Serine/threonine-protein kinase PrkC</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">prkC_13</name>
        <name evidence="3" type="ORF">Mal33_51920</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011717">
        <property type="entry name" value="TPR-4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07721">
        <property type="entry name" value="TPR_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="90"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV59164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="776" mass="85804" checksum="83A6916AB9A77202" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1J8</accession>
    <name>A0A518J1J8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Exopolysaccharide synthesis, ExoD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_52360</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010331">
        <property type="entry name" value="ExoD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41795">
        <property type="entry name" value="PTHR41795"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06055">
        <property type="entry name" value="ExoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF033239">
        <property type="entry name" value="ExoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="140"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="166"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="191"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="210" mass="22822" checksum="D29BC5540DF07DB5" modified="2019-10-16" version="1">MSEGSYRSTIRRSHGVEQNVPNAPLSTILRRIDSLTKEQETISFGNALDAAGQHSFAPILLTIGLIMMAPGPADIPGVPVVLGVLIIIVAAQILIGRKHVWVPQWIERRKIRSKRVHTMIDHVMPWAQRLDRITKPRYSWLLRHAGGGIVAIACILIALTTPLLEFVPMSANVAGAAIATFALALLSKDGLLAGVAIFFSVAMVAWGLFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1K8</accession>
    <name>A0A518J1K8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transaldolase</fullName>
            <ecNumber evidence="1">2.2.1.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">tal_3</name>
        <name evidence="1" type="ORF">Mal33_52370</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.2.1.2" evidence="1"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004801">
        <property type="term" value="F:transaldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001585">
        <property type="entry name" value="TAL/FSA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10683">
        <property type="entry name" value="PTHR10683"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00923">
        <property type="entry name" value="TAL_FSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="427" mass="47496" checksum="E1878332390F2432" modified="2019-10-16" version="1">MSTNTHPTGTVTETIQPDTEQAKQIAEFIVRDIRSDDSLRATADAAFWKRINPTETQLWIDSGDIPTIDSLWNAQFSGLTTNNSLLNQEIQRGNYDHLVPQAAKLLPGISETARVREIAFILNVRHALKLVDRFQCDVSVELHTDVANDLESTLAYARRCHKVCAENFVVKVPLTPAGLVAIKQLSGEGIRVNCTLGFSARQNYLATQFARPAFVNVFLGRLNSYIEANDLGSGEFIGEKTALASQAAISAWSENKPSRRTRQIAASLRDATQLPLLAGIDVITMPPDVARQAMDVLYDPWQSQLQHVHAAELAPNVDREFVSVDKLWDVTDLERQFVRAAAEKQSLTPRQLRQMAVDHGIDDLFPQMTQEQLQTIADEGKVPVHAHWQERIRDGSLAIDSLMTLAGLAAFAADQSQLDRRIREQLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1M1</accession>
    <name>A0A518J1M1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF58 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_52650</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002881">
        <property type="entry name" value="DUF58"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01882">
        <property type="entry name" value="DUF58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF58" evidence="1">
        <location>
            <begin position="47"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="311" mass="34790" checksum="FB7F275C630B33C4" modified="2019-10-16" version="1">MKARVTITLEDLMMLKADARGFSLTPRQPVGSLLAGRHASRLRGRGLMFEELRHYHQGDDIRLMDWKATARLRSPHVRVYSEERERPVLMVVDQRSPMFFGSRRAMKSVAAAEVAALGSWRALDSGDRVGGLVFNDHEIAEVRPHRSQNRVLQLFHQVVRLNGQLADPSAKQNETAAGEQPIQLNAVLEHALQVVKHDHLVVVISDLDGADDQTQQLTSRLAAHNDVLIVAVYDPLGISINGAPGMLAHDRGRVWEISNSPGFRDEFQATFQRLLDHWKEIFHGLRVPVLPISTASPVAPQIRSLFGNQSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1M2</accession>
    <name>A0A518J1M2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_52740</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002763">
        <property type="entry name" value="DUF72"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036520">
        <property type="entry name" value="UPF0759_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30348">
        <property type="entry name" value="PTHR30348"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01904">
        <property type="entry name" value="DUF72"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117396">
        <property type="entry name" value="SSF117396"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="290" mass="33080" checksum="1B8EC6FB777B5F3D" modified="2019-10-16" version="1">MSPLYRLGCPLWACPDWQGSLYKPGAPAAQWLSQYSRVFRTVEEPISRGGIVDLRKVKRWCRATPDDFRFVLPFPRSVTDDAMLQGELLDLDTFLDLLSVLQDHDRLGPSRLQLPPAFDGPKLPVLEHFLESMPVEFPIAVETQHPDFFADAPAGRKLHRLLKRLRLDRSIVAEWDPDDPVTEAAANESRRIRFPEQVRCDATGPMPMLRLCGARLDQLLVPTWLDVWADVVAEWIVKKKRPYVFIDVENVSDGPVIAEMFHERVQALLPEVAAMPRWPGRGLAVQLQLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1N6</accession>
    <name>A0A518J1N6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_52820</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="968" mass="104789" checksum="25496C11CF1A1AAE" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1R1</accession>
    <name>A0A518J1R1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TadE-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_52980</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012495">
        <property type="entry name" value="TadE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07811">
        <property type="entry name" value="TadE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="308"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV59270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="360" mass="39716" checksum="8BD57EFEE61DFBCF" modified="2019-10-16" version="1">MRPRQGSLSAANRRGQALLEFAILVPVIILLIGATISFGLFFFRANVLQQAVDVTAQEISRMSLPPDRELGLGRLESYTVAADSCVDPNPIAGDPDFKQRIYDEKYLIIPVSDYEDCDDGLQDFADSLPLLNRLLISVMVTDFVDGQQVLRYPGAIVRNTCSDQRTVLIPIVKYCHRDLSEPPPFPNDNPPPGGFVPSTIHTAGEMIVKWVAPVEEIRVDHDGDGDTPPESPFKLCYHTDPTLPSFEPGMVALRINYPQQATTIINRIALVDDVDNPNRKLGSSIVIVGDTVVAPGVDLGVCYQIEEPSERRSPASHQPGSNPNAGTYGLGELEALTRIVRPYRKVMSFQAIYRREVFGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1V8</accession>
    <name>A0A518J1V8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transport permease protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">tagG</name>
        <name evidence="8" type="ORF">Mal33_53390</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the ABC-2 integral membrane protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC_2_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000412">
        <property type="entry name" value="ABC_2_transport"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51012">
        <property type="entry name" value="ABC_TM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="61"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="95"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="135"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="169"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="204"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="257"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="domain" description="ABC2_membrane" evidence="7">
        <location>
            <begin position="44"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV59311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="291" mass="33255" checksum="B2F785637457F502" modified="2019-10-16" version="1">MPSAIESVAEPLPDQSVSNDYELVLEAGRAERHYWHDLWRYRELFQVLAWRDVSVRYKQTVIGVAWAVIRPFLTMVVFTVIFGRLAKLPDNGVPYPLLVFAGMLPWQFFSTALADASNSLVTNANLISKVYFPRLIVPTATVVVAFVDFLISFSIMAAMMLFYGYLPPWQIILLPIFVLLAFLASLGPSLWITSLNVRYRDFRYIIPFIVQFGLYVSPVGFSSDIIPGEYRWLYSLNPVVGVIDGFRWCLLGGENHIYMPGFVTSLAVTGVMLWLGIRQFRKMERRFADLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J202</accession>
    <name>A0A518J202_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hpt domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_53930</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036641">
        <property type="entry name" value="HPT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008207">
        <property type="entry name" value="Sig_transdc_His_kin_Hpt_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01627">
        <property type="entry name" value="Hpt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47226">
        <property type="entry name" value="SSF47226"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50894">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HPt" evidence="2">
        <location>
            <begin position="19"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphohistidine" evidence="1">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV59365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="115" mass="12402" checksum="09C9120703B3C78C" modified="2019-10-16" version="1">MNEEQSVRFATALKRLSGDVELLSSMAMIVSDDVPGIVAELEEQLEAGDSAGVVASAHKLKGMCSTFETGHPVTALEDVLHAARGGDVSTARELYRRCQPDLRELMQEISKLAQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
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    <name>A0A518J254_9BACT</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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            <taxon>Planctomycetia</taxon>
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    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="102" mass="11417" checksum="C8A6CE36358EAFCF" modified="2019-10-16" version="1">MAHKDTFRIVTRASDGNLQIRDFPNADPILHMHSQIGIDDCSTDLGLRGMPVFRGLVGPIPEGKNVVRYESPEVFESLTKEWGAEKKKRRTRLRTAAPTAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J2A6</accession>
    <name>A0A518J2A6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="4" type="ORF">Mal33_55070</name>
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    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
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        <lineage>
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            <taxon>Rosistilla</taxon>
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    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DUF1254"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
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        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021845761" evidence="1">
        <location>
            <begin position="25"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1254" evidence="3">
        <location>
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            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1214" evidence="2">
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            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF06863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV59472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="465" mass="51876" checksum="F92A99F47D33E70D" modified="2019-10-16" version="1" precursor="true">MNRKHLTALLAALVAFAISSSGLAQDVTPEEARAIAKEAYIYGYPLVDSYRIQYAYFVDKDDKSYKAPWNQIKNIPAVYTPADTAIQTPNSDTPYSFVGLDLRSEPIVISVPEIEKSRYYSVQFIDAYTFNFAYVGSRATGNNAGNFLVAGPNWKGDKPAGIKQVIRSETDFDMVVFRTQLFNPADIDNVKKIQAKYKVQPLSAFLGTPTPPAAPAVDWAKPLTQEEEKTSLEFFNVLNFVLGYCPVDPTEVELRKRFAKIGIEGGKSFDPAKLSPELKTAIEQGRADAWEAYAGDAKLLEAGKITPGDCFGTREYLKNNFLYRWLATIGIYGNSKQEAMYPVYQVDSAGHPLNGANRYTLRFAKGELPPVKAFWSLTMYDQPQSLLVANPIDRYLINSPMLPELKKDADGGLTLYIQNDSPGKERESNWLPAPKGPFAMYMRLYWPAEAALDGTWKAPKLNLVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J2C7</accession>
    <name>A0A518J2C7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Citrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Mal33_55220</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1450">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004680">
        <property type="entry name" value="Cit_transptr-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006037">
        <property type="entry name" value="RCK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036721">
        <property type="entry name" value="RCK_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03600">
        <property type="entry name" value="CitMHS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02080">
        <property type="entry name" value="TrkA_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116726">
        <property type="entry name" value="SSF116726"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51202">
        <property type="entry name" value="RCK_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="28"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="80"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="117"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="161"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="200"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="419"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="464"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="489"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="525"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="548"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="588"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="domain" description="RCK C-terminal" evidence="7">
        <location>
            <begin position="226"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="domain" description="RCK C-terminal" evidence="7">
        <location>
            <begin position="315"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV59487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="611" mass="65196" checksum="24D81B20A9EA1157" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ILU4</accession>
    <name>A0A518ILU4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATPase family associated with various cellular activities (AAA)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_00090</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011703">
        <property type="entry name" value="ATPase_AAA-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041628">
        <property type="entry name" value="ChlI/MoxR_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07726">
        <property type="entry name" value="AAA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17863">
        <property type="entry name" value="AAA_lid_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_3" evidence="1">
        <location>
            <begin position="52"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="AAA_lid_2" evidence="2">
        <location>
            <begin position="264"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="334" mass="36691" checksum="D90FDE3A744CE7DE" modified="2019-10-16" version="1">MTIAIESAEEEAEIVQQLRQGRSAIESELAKVIIGQQDVIEQLIISLFAGGHCLITGAPGLAKTLLVSSVAKIFHLDFQRIQFTPDLMPADITGTEILEDLGDGRRAMKFVRGPIFGNVILADEINRTPPKTQAALLEAMQEHQVTAAGSRHPLPEPFFVLATQNPIEMEGTYPLPEAQLDRFLFNVLIDYLPHEDELAVVMQTTSKKTEPIQPLFTGVDVLKFQEVVRRVPIAKEVASYAVQLAAATRPNREGSLDFINQWVTWGAGTRAAQTLVLGAKARALLNGHSHVSLEDIRALAKPTLRHRVLLGYKAEAEGITVDQTIQRLLDTTLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ILZ4</accession>
    <name>A0A518ILZ4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_00240</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10600">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021866">
        <property type="entry name" value="SpoIIAA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038396">
        <property type="entry name" value="SpoIIAA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11964">
        <property type="entry name" value="SpoIIAA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="122" mass="14249" checksum="76B2F3570D227209" modified="2019-10-16" version="1">MSFVITEHAEGQVVEIQLTGKLSKEAYEKFVPMTEAKIAEYGKVRMLVIMHDFHGWEAGALWEDIKFDFKHFNHIERLAIVGESKWEKGMTVFCRPFTTAKIKYFDHDEIGAAREWIHESND</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IM43</accession>
    <name>A0A518IM43_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Exopolyphosphatase</fullName>
            <ecNumber evidence="2">3.6.1.11</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ppx</name>
        <name evidence="2" type="ORF">Mal33_00900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.6.1.11" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004309">
        <property type="term" value="F:exopolyphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003695">
        <property type="entry name" value="Ppx_GppA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030673">
        <property type="entry name" value="PyroPPase_GppA_Ppx"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02541">
        <property type="entry name" value="Ppx-GppA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001267">
        <property type="entry name" value="Pyrophosphatase_GppA_Ppx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ppx-GppA" evidence="1">
        <location>
            <begin position="20"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="513" mass="57249" checksum="455531243F24D5CE" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IM70</accession>
    <name>A0A518IM70_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Macrolide export protein MacA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">macA_1</name>
        <name evidence="3" type="ORF">Mal33_01250</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HlyD_D23" evidence="2">
        <location>
            <begin position="67"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="409" mass="43969" checksum="D032DFE6125AF3AE" modified="2019-10-16" version="1">MHVPTLSSIVSPRAHCIGVAACLSLLMAATGCDSPAAAMKSEPKPEPLETIEAELMTVALQPWPTIVRSQGSLDADEESVVGAKVAGRVAEVHVDLGDYVNVGDPLVTLDQAEFQLKVDQTEAQLEQARAAVGLRAGVPVSELNPENAPPVRQQRALWEEAQSSLKRLESLRVQKAVSEGEYELAAAAERVAEARYASALNGVYEKIAAIGSYQAELSLARNQLTDAIIRSPLEGFIHQRLTAPGSYISVGQSIAVVVRTSPLRFRSSVPERRAQALSLGQQVRLQIESVPEPRTATITRISPMLDQQSRSLVFEAEIENEGQELRGGLFAEAEIVVDDDATGLVVPQSAINEFAGAEKAWKVVDGALVEQEVLIGKRRDGQLEVLKGLQSGDVILRDASQGRIAKIKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMA5</accession>
    <name>A0A518IMA5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Sec-independent protein translocase protein TatC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">tatC2</name>
        <name evidence="5" type="synonym">tatC</name>
        <name evidence="7" type="ORF">Mal33_01820</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Forms a complex with TatA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the TatC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033281">
        <property type="term" value="C:TAT protein transport complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043953">
        <property type="term" value="P:protein transport by the Tat complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00902">
        <property type="entry name" value="TatC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019820">
        <property type="entry name" value="Sec-indep_translocase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002033">
        <property type="entry name" value="TatC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30371">
        <property type="entry name" value="PTHR30371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00902">
        <property type="entry name" value="TatC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00945">
        <property type="entry name" value="tatC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01218">
        <property type="entry name" value="TATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0811">Translocation</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="39"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="246"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="283"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="330"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="365"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="389"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="121"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="146"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV54232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="427" mass="46868" checksum="0211BD840C6AEA3D" modified="2019-10-16" version="1">MNQAKAQNALNTAKAPKDDLFEGSTMTFGEHLEELRKSLLKAAVWLAFGLAIGLYFADRVVQFVQVPLEGAITRFMADQTLYKMDIDPHAADAQPMKRWLIEKGMIYETIYMVDEKAVEQEEAQRQENEQKAKAAAAAKPKPAAAAKADTAKKSEKEPAAKPDDEAKPAAKPKPTDAKPSAEPAKPTAGETEAKATEATGGSLTTIDAQVPDAVFENPEKNLKPVTIWRSAGAGLSSFQMEEPFMIWLKAGLVIGAIIGSPGIFFHIWNFVAAGLYEHERKYVYIYMPFSVVLFVSGVVLAFFLVLQYVLDFLLTFNATLNVDLVPRLSNYVNFVLLLPLGFGIAFQLPLVMLFLQRIGLFATEAYISSWRIAVLVIAVLSMILTPADIYSMIALMVPLILLYFLGIGLCKFMPKGRGIGSQGYDPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMC4</accession>
    <name>A0A518IMC4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Outer membrane biogenesis protein BamB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_01730</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008092">
        <property type="term" value="F:cytoskeletal protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002372">
        <property type="entry name" value="PQQ_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007131">
        <property type="entry name" value="SHD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13360">
        <property type="entry name" value="PQQ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03983">
        <property type="entry name" value="SHD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021947229" evidence="2">
        <location>
            <begin position="24"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="domain" description="SHD1" evidence="3">
        <location>
            <begin position="18"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV54223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="491" mass="52898" checksum="7C5C15039BCD4FC7" modified="2019-10-16" version="1" precursor="true">MSSLRIAYSFCLGMLLFASPASARTWTDSTGAYKIEADFVGFDGSIVQLKKADGSISRLPIARLSHRDQVWVRAEMKRQTMPTDEPADSAAEGLASTDWPGWRGPQRDGISREQGLLKEWPSGGPPLLWSSRGLGNGFSSLAIAGDKIYTMGKKGGQVQLVCASRDDGRVIWETPVGDGSDPNCTPTLDVEAGLVYGLSHAGDLLCASASDGEVVWRKNFPNDFGGRMMSMWGYSESPLIDGDRLICTPGSDRAVMAALDKKTGDVIWQTPMQEGTAGYASPVISHAGGIKQYVNLVGKGLIGIRAADGEPLWHYPRVANTTANVPTPLVNGNFVFCSSGYGDGGSALLELKKQGRTIRYREVYYKDNRTLQNHHGGMILIDGKIYMGHGHNQGFPRCVDLRSGRTVWGEGQRGPGKGSAAIVAADGHLIFRYEDGVVALIEANPGGYQLKGEFKPASVNGKAWAHPVIAGKRLYLRDQDELHCYDIGAGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMK7</accession>
    <name>A0A518IMK7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_02550</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="108" mass="11792" checksum="C347AFC1EB63981B" modified="2019-10-16" version="1">MDAMQLLQWVNNPSVIVGLFSTAVILVAIDFQFPIDWPAHLGYVAFALGLFLVIPLNLVASTFVGVLGWLLLEIMHALLFGRFLTNAPGRARSRPAVDDSSEPLDLDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IML5</accession>
    <name>A0A518IML5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DDE_3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_02650</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038717">
        <property type="entry name" value="Tc1-like_DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13358">
        <property type="entry name" value="DDE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0814">Transposable element</keyword>
    <feature type="domain" description="DDE_3" evidence="2">
        <location>
            <begin position="39"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="231" mass="27188" checksum="EEEB8D020A59B886" modified="2019-10-16" version="1">MTNRKIQYWVIPPDADSEFVACMEEVLDTYEEPYDSDYPVVCMDEQPVQLHKETRTPIPATRYHARRVDYEYERCGTASVFMFTEPLAGWREVTVRPKRTKVDWAIEMEALLTTRYKKAKKIILVCDNLNTHTKGAFYEAFKPEKARALVRRIEFRYTPKHGSWLNAAENELSSMTRQCINGRRFATIAPLRKETQAWSSHSNRRQRGVNWQFQVKDARTKLKSLYPQIKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IN29</accession>
    <name>A0A518IN29_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">WecA-like glycosyltransferase</fullName>
            <ecNumber evidence="7">2.7.8.33</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Mal33_04420</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.7.8.33" evidence="7"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008963">
        <property type="term" value="F:phospho-N-acetylmuramoyl-pentapeptide-transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036380">
        <property type="term" value="F:UDP-N-acetylglucosamine-undecaprenyl-phosphate N-acetylglucosaminephosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000715">
        <property type="entry name" value="Glycosyl_transferase_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22926">
        <property type="entry name" value="PTHR22926"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00953">
        <property type="entry name" value="Glycos_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="54"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="106"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="158"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="185"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="215"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="246"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="277"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="319"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="350"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV54488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="380" mass="40639" checksum="1B960AB9853CD17D" modified="2019-10-16" version="1">MLDLRSLLFLLAVTVLPAAIISWIVVAVVRRFAEPLGLVDRPGERKVHTTPTPLGGGIGIWAGIIGTFLAGSITVWYLIDLPIIANLLPASVLEHVDGLRFRTRELWLVLGAGTVLTLLGLVDDWRGLPATLRLAIEFAVAIASVLVLGYGLTAFIPVPLVTSTLSVIWIVALINSFNMLDNMDGLSGGVAAIIAAMLAAVMLLSPDPDTQQPQFFVAALLLVVVGSLLGFLWHNRPPAKIFMGDAGSYLVGFLIGIATLAATYAGYQGSERPHGVLAPLCVMAVPLYDMTTVLWIRIREGRSPFVADKSHFSHRLVDLGLTKVQAVLTIYLVTGTCGLAALLLGRVDSQAAIIVVGIVLCMLALVVILESTGWRRKNKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IN84</accession>
    <name>A0A518IN84_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Metal-dependent hydrolase YfiT</fullName>
            <ecNumber evidence="2">3.-.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">yfiT</name>
        <name evidence="2" type="ORF">Mal33_05140</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.-.-.-" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024775">
        <property type="entry name" value="DinB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12867">
        <property type="entry name" value="DinB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DinB_2" evidence="1">
        <location>
            <begin position="15"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="158" mass="17721" checksum="381D54AD00CA9218" modified="2019-10-16" version="1">MALNPLIEEYAAGGAVLRRAVAGFSEAQFDAVPIPGKWSTRQVLCHIADFELVYADRMKRVIAEDEPTFFGGDPDQFAAGLAYDQRDAEEELQLVEAVRAQVTRILRTLDDADFQRIGNHHEDGPLTLAALLEKIAGHLQHHVRFIEEKRVVLEGMQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ING4</accession>
    <name>A0A518ING4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">50S ribosomal protein L31</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 8" type="primary">rpmE</name>
        <name evidence="8" type="ORF">Mal33_05830</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Binds the 23S rRNA.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.830.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00501">
        <property type="entry name" value="Ribosomal_L31_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034704">
        <property type="entry name" value="L28p-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002150">
        <property type="entry name" value="Ribosomal_L31"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027491">
        <property type="entry name" value="Ribosomal_L31_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042105">
        <property type="entry name" value="Ribosomal_L31_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33280">
        <property type="entry name" value="PTHR33280"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01197">
        <property type="entry name" value="Ribosomal_L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01249">
        <property type="entry name" value="RIBOSOMALL31"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143800">
        <property type="entry name" value="SSF143800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00105">
        <property type="entry name" value="L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01143">
        <property type="entry name" value="RIBOSOMAL_L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0687">Ribonucleoprotein</keyword>
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        <location>
            <position position="16"/>
        </location>
        <ligand>
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        </ligand>
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        </source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV54628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="78" mass="8678" checksum="BDC88577EA27B0CF" modified="2019-10-16" version="1">MKEGIHPNYQATEVTCGCGNTFTTRSVQPELKIDICNMCHPFYTGKLKFVDTAGRIDKFQKKFAAGSYASLAKGKKKK</sequence>
</entry>
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    <name>A0A518INI8_9BACT</name>
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
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                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
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                <person name="Storesund J.E."/>
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                <person name="Lage O.M."/>
                <person name="Pohl T."/>
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                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5 6">Mal33</strain>
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        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
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        </location>
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        <source>
            <dbReference type="EMBL" id="QDV54651.1"/>
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        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="540" mass="60145" checksum="BAD1248995241820" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
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                <person name="Rohde M."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="6 7">Mal33</strain>
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    </evidence>
    <sequence length="845" mass="94360" checksum="06A86B51082F3636" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
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    <name>A0A518INJ6_9BACT</name>
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        <submittedName>
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        </submittedName>
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    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
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                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
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                <person name="Kallscheuer N."/>
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                <person name="Merkel B.J."/>
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                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
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    </dbReference>
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    </dbReference>
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        <source>
            <dbReference type="EMBL" id="QDV54657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="357" mass="39471" checksum="B7EBB62CA7238D84" modified="2019-10-16" version="1">MKIQDLPAAVRENVRRGTVIPAQPLALDAQRKFAPRYQTALTRYYIDAGAGGIAVGVHSTQFAIRDPSIGLFKPVLSLASEVIDQYAGDQGRELFKVAGVCGETPQAVAEAQFAVSQRYHACLLSLAALAESSIDDLLDHCREVAEIMPVIGFYLQPAVGGRVLPYRFWREFAEIENVIAIKLAPFNRYQTLDVVRAVCDAGREDAITLYTGNDDNIIADLITPYRMVTERGVKSVRIRGGLLGHWCVWTRAATSLLDEIHRTIERGGDIPSELLSRNIEVTDCNAAFFDAANNFAGCIPGIHEVLRRQGLLPGTWCLDPDEVLSPGQSEEIDRVLAAYPHLNDDAFVREHLSRWLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INQ0</accession>
    <name>A0A518INQ0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DNA utilization protein GntX</fullName>
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    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_06730</name>
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    <organism evidence="3 4">
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        <lineage>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044005">
        <property type="entry name" value="DZR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18912">
        <property type="entry name" value="DZR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DZR_2" evidence="2">
        <location>
            <begin position="42"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="domain" description="Pribosyltran" evidence="1">
        <location>
            <begin position="172"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="274" mass="29746" checksum="F711F07EE95B4F89" modified="2019-10-16" version="1">MAVQRKFPFMAADRSARAAPTCGLRRDSGWSHVPLSIARAFLEMIYPPTCTLCGGALVDPGAIEMCDACIDAVRGKCRHWCRRCGMPMEPMRLGEPTCNRCLKQKLPFAEVVVLGRYEGAMREAVIAGKKFIHEPLMMALGGLLGEQIASQVDSIPEIVTYVPSHWRRRLKRGTVPAATLAKQVGRVLGLPVHPAVRSVRGTIKQGKLAAGQRAENISNAFAVRRRYHPNGHSYLLIDDVMTTGATMSEVTRVLLAAGATRVCVAATARGVGKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INQ2</accession>
    <name>A0A518INQ2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC-type transporter ATP-binding protein EcsA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ecsA</name>
        <name evidence="5" type="ORF">Mal33_06840</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="45"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="77"/>
            <end position="84"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV54724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="291" mass="31179" checksum="58C949C479A62072" modified="2019-10-16" version="1">MGQPRAVAIELLIGRIDLSMSIRLGWTCKTSFEAHCQTAPATLMIRAIDFHKAYDDTIAVAGLSFEVLPGQVLGLVGPNGAGKTTTLRALSGLIPATRGRLEVAGLDVEQHPIAVKQQTAYVPDDPQLFDDLTVGQHMDFFASVYRVADADSKTQQLLQTFDLIEKVDQRASALSRGMRQKLAVCCAYLYSPAAILLDEPMTGLDPPGIRNLLESVRQRAADGAAIMISSHLLAMIESVCTDVLVLERGRAKFCGPIDAFKARFESAGTPASLEQAFFAATACELPVGASG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INX2</accession>
    <name>A0A518INX2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ACT_8 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_07520</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045739">
        <property type="entry name" value="ACT_dom_pair"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19571">
        <property type="entry name" value="ACT_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ACT_8" evidence="1">
        <location>
            <begin position="23"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF19571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="165" mass="18361" checksum="4D50A7906B3B4761" modified="2019-10-16" version="1">MSSIGEGNAIDYQTARGRDYPAIRQFTVFLENRVGQLLEVVRRFEGTGLRIVALSINDAAECAFVRFVVSHPERAREILERAGLSIIETDLIGVELPDTSQPLLHVCTALLQAEVNIIQAYPLIPRTNQRAAVALMVDNIDLGIETLRAKNFRTLQESDLLGEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INY7</accession>
    <name>A0A518INY7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Apolipoprotein N-acyltransferase</fullName>
            <shortName evidence="8">ALP N-acyltransferase</shortName>
            <ecNumber evidence="8">2.3.1.269</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8 11" type="primary">lnt</name>
        <name evidence="11" type="ORF">Mal33_07700</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>a glycerophospholipid + N-terminal S-1,2-diacyl-sn-glyceryl-L-cysteinyl-[lipoprotein] = a 2-acyl-sn-glycero-3-phospholipid + H(+) + N-acyl-S-1,2-diacyl-sn-glyceryl-L-cysteinyl-[lipoprotein]</text>
            <dbReference type="Rhea" id="RHEA:48228"/>
            <dbReference type="Rhea" id="RHEA-COMP:14681"/>
            <dbReference type="Rhea" id="RHEA-COMP:14684"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:136912"/>
            <dbReference type="ChEBI" id="CHEBI:140656"/>
            <dbReference type="ChEBI" id="CHEBI:140657"/>
            <dbReference type="ChEBI" id="CHEBI:140660"/>
            <dbReference type="EC" id="2.3.1.269"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">Protein modification; lipoprotein biosynthesis (N-acyl transfer).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.269" evidence="8"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00666"/>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016410">
        <property type="term" value="F:N-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042158">
        <property type="term" value="P:lipoprotein biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01148">
        <property type="entry name" value="Lnt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004563">
        <property type="entry name" value="Apolipo_AcylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045378">
        <property type="entry name" value="LNT_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20154">
        <property type="entry name" value="LNT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="SSF56317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00546">
        <property type="entry name" value="lnt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 11" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2 8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="34"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="61"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="84"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="118"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="162"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="202"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="CN hydrolase" evidence="10">
        <location>
            <begin position="236"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="566"/>
            <end position="589"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QDV54805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="589" mass="64390" checksum="CC849C21EF1CEF6C" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INZ7</accession>
    <name>A0A518INZ7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Phenylserine dehydratase</fullName>
            <ecNumber evidence="4">4.2.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">psdht</name>
        <name evidence="4" type="ORF">Mal33_07820</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="4.2.1.-" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000634">
        <property type="entry name" value="Ser/Thr_deHydtase_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00165">
        <property type="entry name" value="DEHYDRATASE_SER_THR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PALP" evidence="3">
        <location>
            <begin position="19"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV54817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="334" mass="36508" checksum="9E794CD272C18632" modified="2019-10-16" version="1">MTIPIATIDDVRKAQKVIDQHISPAPLVRSYALEKELGLPPSRRVWLKDYGWTPVGSFKLLGALNWMANHLEAIGDRPVAAHSSGNFASGISFAGMRYQKQVVIVMPDTAPQVKFNLTKSFGAEVHTYDISRDHETGDRDRLTREIVQQRQCVQASPYDDPHVIAGNGVGGLQIVEELKRQQRGVSDFVCQVSGGGLMAGHALAIADGFPQARIIGVEPDGADDFRQSLAAGERVRVERPTSICDGLLSYDVGEHNWPILRKHVASSVTVADLQTRQAMRWLYDKHGLRTEPSGAAATAALLTGQISPDGEGDIVLVVSGRNVDQQPFMDWIEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP30</accession>
    <name>A0A518IP30_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative ABC transporter ATP-binding protein YbhF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ybhF_2</name>
        <name evidence="5" type="ORF">Mal33_08200</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="24"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="57"/>
            <end position="64"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV54855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="340" mass="38417" checksum="782220A6BF2FE8D7" modified="2019-10-16" version="1">MPIIEIEQLTKSYRVYKKQEGLMASVRGLFHREYREVEAVRSIDLTVDEGEFVAFLGPNGAGKTTTLKLLSGVINPTSGTARVMGYTPWQRENGYRRRFALVMGQKNQLWWDLPAQESYRLHQQIYRIDQNAFQRTLDELTDLLDVRRLLGQPVRELSLGERMKMELIAALLHNPDVLFLDEPTIGLDVVAQHNIQQFLRHYQQEKRTTVLLTSHYMKDIIALCQRVVIIASGQIKYDGSLTGIVDAFSGSKVVTLQFAEGHQPGDLTNIGEVLSIDLPKAKIKIARTDIPKRLAAALNEHPIDDVVVEDPPLEDAIADMFNRVRDEEKQAIAATAADSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPD4</accession>
    <name>A0A518IPD4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glycine--tRNA ligase</fullName>
            <ecNumber evidence="7">6.1.1.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Glycyl-tRNA synthetase</fullName>
            <shortName evidence="7">GlyRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 10" type="primary">glyQS</name>
        <name evidence="10" type="ORF">Mal33_09190</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the attachment of glycine to tRNA(Gly).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly)</text>
            <dbReference type="Rhea" id="RHEA:16013"/>
            <dbReference type="Rhea" id="RHEA-COMP:9664"/>
            <dbReference type="Rhea" id="RHEA-COMP:9683"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78522"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.14"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.14" evidence="7"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004820">
        <property type="term" value="F:glycine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006426">
        <property type="term" value="P:glycyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00774">
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    </dbReference>
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    </dbReference>
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    </dbReference>
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            <end position="449"/>
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        </location>
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        <ligand>
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            <position position="216"/>
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        <ligand>
            <name>substrate</name>
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        <location>
            <begin position="248"/>
            <end position="250"/>
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        <location>
            <begin position="258"/>
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        <ligand>
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        </source>
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        </source>
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        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="536" mass="61700" checksum="9EB9717B5800A765" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPE2</accession>
    <name>A0A518IPE2_9BACT</name>
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        </submittedName>
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    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
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                <person name="Bunk B."/>
                <person name="Jeske O."/>
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                <person name="Kallscheuer N."/>
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                <person name="Lage O.M."/>
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                <person name="Rohde M."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">Mal33</strain>
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        </location>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="QDV54975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
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    <name>A0A518IPJ7_9BACT</name>
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        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">Mal33_09720</name>
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    <organism evidence="2 3">
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            <taxon>Planctomycetia</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
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                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
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                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
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            <end position="433"/>
        </location>
    </feature>
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            <end position="421"/>
        </location>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="QDV55004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="433" mass="47861" checksum="9D1F84083D1E7790" modified="2019-10-16" version="1">MHERTQRLICQLVFVVACALPTLLTVSTVLVRSTPWFDNWRRERLENELCDRFGLRFEIGELKVLAPGAMQLERVNVTDPETGADIGSIRVVQFTTRDGRLALRLAQPEVRAPQLPHAWHLLHDRFLCHPELTTNPVRIAADDLSILSTSGGVTLTDLQAYVQPHDYANETIMQFKIAGREMPSPATISITRDRSRRYPETAWKLHTGGTSLPYSLLSDYFPQLPKLGHSCEFNGPVSCRLSRDGWNIDLGGSSITGIEVSRVFDNLAHKLTGTADVWLGQCRIEQGLLTNIAGGVTIRNGQLGDSLLQSSNHLLGVQSLVANNRPAHPFDLMQFRFAMDEAGWQFIGACDADNRNLPAGILAVQANRPIAVLSTPQPLAISAPKQLVAPEYSQPLFAGEPNNPVLDLLPSPPPQPPYLQSPLVPRVTMRSQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPQ5</accession>
    <name>A0A518IPQ5_9BACT</name>
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        <submittedName>
            <fullName evidence="3">Tripartite tricarboxylate transporter family receptor</fullName>
        </submittedName>
    </protein>
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        <name evidence="3" type="ORF">Mal33_10320</name>
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    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
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            <taxon>Planctomycetia</taxon>
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            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0065 (bug) family.</text>
    </comment>
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        <property type="protein sequence ID" value="QDV55063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005064">
        <property type="entry name" value="BUG"/>
    </dbReference>
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        <property type="entry name" value="Bug_dom1"/>
    </dbReference>
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        <property type="entry name" value="DUF1468"/>
    </dbReference>
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        <property type="entry name" value="PTHR42928"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07331">
        <property type="entry name" value="TctB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03401">
        <property type="entry name" value="TctC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0675">Receptor</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="373"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="437"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="462"/>
            <end position="484"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="489" mass="52278" checksum="F865F3E25CC0ABDB" modified="2019-10-16" version="1">MGDTGLLSLVETMATDRPSHCKLPFDLLCKASLKHLFSERETFRHARVLCAAMVAVSCFVIGCGSDQEFPSRPLTLICPWSAGGGTDRIARQVAVQLEEELGVPVNVVNATGGGGVTGHSRGALASPDGYTLTLATVELNMLHHRGLSAVGPDDYQPLGLLNRDPAALFVHKRSDWQSLADVEAALAERAEPMNASGTAAGGIWHAALIGWVAQCGLPSESVNWISINGAAPSLQELMAGGIDLVCCSIPEARAMLDAGEIRCLGLMADERSPAAPDVPTFREQGDDWSLSSWRGLLCPRGVPPERVEVLEAAVDRLSRSPKFVEFMDSGGFQTSIADASEFTEFLSRSDRQFAETLGSPAFVQSQTAVVRPYFFPICLGILGLIFVVPACRSQAAVATEPSATESSDVQSRSRWLRPVVVILAVIAFVATCETIGYVLATAALMWLLAIVFGATRRQTAGVTLLAAPLLYQLFARTLGVPLPWGWLGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQK2</accession>
    <name>A0A518IQK2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Methyltransferase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_13360</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016279">
        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026170">
        <property type="entry name" value="FAM173A/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13610">
        <property type="entry name" value="PTHR13610"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_25" evidence="4">
        <location>
            <begin position="85"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV55365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="223" mass="25629" checksum="A834E5A144422535" modified="2019-10-16" version="1">MATTEFLKRVFSTRPTSTIQSALSVYDDYLFDKRYQLDTRSEVAINDLDISQEDKQHADKYKPTRARYFRKIMEKVVLPRDGVFVDVGCGKGRILLLAAEQGFDQVVGLEISPALCQIAERNVETFKEARPKTGSIKVVCTNILDYQMDGSETVLFLYSPFGYSVTERFLEMVRKSLKDHPRDVCLIIDEFRFPELLAGDDYFEQSLIYKYGAAVFHVYSHIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQU7</accession>
    <name>A0A518IQU7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF58 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_14130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002881">
        <property type="entry name" value="DUF58"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01882">
        <property type="entry name" value="DUF58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF58" evidence="1">
        <location>
            <begin position="37"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="321" mass="36258" checksum="9B593BC3B88CC4B1" modified="2019-10-16" version="1">MLPREIIRRVREIQVQTGRQVADVLAGQYVSVFKGRGIEFDEVRPYVPGDDVRTIDWNVTARTGEPFVKRYVEERQLTLMVMADVSASQDFGSATRSKREATAELAALLAFSATRNDDKVGLALFHGGIDQYIPPRKGQKHSLRVVREVLAHGNVETKSGTTPAKRPRRWLPFGRRRAWLRTGRQATDVGGAMEFLMSVTSRKTVCFVISDFLDDGYLKAMQSANRKHDVIAVLITDPKEREIPNVGMVNVADPETGRVQRYDTGSIAFRDHVAAASEDRIDQLRRSFGSSGIDFIHIDASKSVVDPLVRFFRMRSRRMHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQY5</accession>
    <name>A0A518IQY5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_14550</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="265" mass="29235" checksum="4518C8798AF53CC2" modified="2019-10-16" version="1">MTTTAPNVQRTTGILNRTEAAEILGTVPIAVSRLIAWNQLAYNRAADGTPLILEADLQRYVGAGTRNLAMPGVQGGWLGGDLSSNDSFVKKFRQFVADVEVTDDHVREMYENQKKSSYLTAGIRITPAMREAYNAGATTLSSGKVRPSGDWSAVDPEKFPLAKLSAGQRFFAGVLRRHARRFVDRKQNGAFDPSPIEKLYSSPDAFRAALEYAAKAARSESVFLTEWRTLPEFPHKKFSIRKEISLAAIPADFENEMALVASKCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IR34</accession>
    <name>A0A518IR34_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">1,5-anhydro-D-fructose reductase</fullName>
            <ecNumber evidence="2">1.1.1.292</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">afr_3</name>
        <name evidence="2" type="ORF">Mal33_15310</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.1.292" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033712">
        <property type="term" value="F:1,5-anhydro-D-fructose reductase (1,5-anhydro-D-mannitol-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GFO_IDH_MocA" evidence="1">
        <location>
            <begin position="1"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="342" mass="37293" checksum="4A8BBC2D5F9A4571" modified="2019-10-16" version="1">MRAGIAGIGFMGWIHYLAYQRATGAELVAFCTRDPQRRGGDWTGIQGNFGPPGKQIDVSDLSVYETLDEMLENDSIDLIDICLPVHLHVDAVRKCLEAGKHVLCEKPLALNADDAASLVELAKSKGLHLMVAHVLAYLPEFRLLVDAQQSGKYGKCLGGRFKRVIGPVDWNPDFYNPEKVGGPLIDLHVHDAHLLRLLFGMPKEVISRGRMRGETASYFESMMTYDDPDVIVSVGGGTIDQHGRPFTHGYEVHFERATIQFEFAGFDDGTELMPVKIIHEGGKIELPELGSGDPADAFVIEVQTAADVLAGKDPGALAGQLAADALQICELELKSIKNNTSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRE7</accession>
    <name>A0A518IRE7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase IS200 like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_16270</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002686">
        <property type="entry name" value="Transposase_17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036515">
        <property type="entry name" value="Transposase_17_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01797">
        <property type="entry name" value="Y1_Tnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01321">
        <property type="entry name" value="Y1_Tnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143422">
        <property type="entry name" value="SSF143422"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Y1_Tnp" evidence="1">
        <location>
            <begin position="5"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="151" mass="17553" checksum="FE9D42DB22F44209" modified="2019-10-16" version="1">MSQSLAQVWLHIVFSTKVRRPFLQDDAVRDEMFRMLAYRVKEAKCFSASVGGHFDHVHLLVGLARTVTIANLVEHIKTETSQWAKTAKNCSSRFSWQAGYAAFSVSHSQRGVVDKYIRNQGQHHQRLGFKDEFRAICKRHEIEIDERYAWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRJ9</accession>
    <name>A0A518IRJ9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Pyridoxine 5'-phosphate synthase</fullName>
            <shortName evidence="2">PNP synthase</shortName>
            <ecNumber evidence="2">2.6.99.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2 3" type="primary">pdxJ</name>
        <name evidence="3" type="ORF">Mal33_16890</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>1-deoxy-D-xylulose 5-phosphate + 3-amino-2-oxopropyl phosphate = H(+) + 2 H2O + phosphate + pyridoxine 5'-phosphate</text>
            <dbReference type="Rhea" id="RHEA:15265"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57279"/>
            <dbReference type="ChEBI" id="CHEBI:57792"/>
            <dbReference type="ChEBI" id="CHEBI:58589"/>
            <dbReference type="EC" id="2.6.99.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; pyridoxine 5'-phosphate biosynthesis; pyridoxine 5'-phosphate from D-erythrose 4-phosphate: step 5/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homooctamer; tetramer of dimers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PNP synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.6.99.2" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00244">
        <property type="reaction ID" value="UER00313"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033856">
        <property type="term" value="F:pyridoxine 5'-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008615">
        <property type="term" value="P:pyridoxine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00003">
        <property type="entry name" value="PNPsynthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00279">
        <property type="entry name" value="PdxJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004569">
        <property type="entry name" value="PyrdxlP_synth_PdxJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036130">
        <property type="entry name" value="Pyridoxine-5'_phos_synth"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30456">
        <property type="entry name" value="PTHR30456"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03740">
        <property type="entry name" value="PdxJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63892">
        <property type="entry name" value="SSF63892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00559">
        <property type="entry name" value="pdxJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2" id="KW-0664">Pyridoxine biosynthesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="1-deoxy-D-xylulose 5-phosphate binding" evidence="2">
        <location>
            <begin position="9"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="region of interest" description="3-amino-2-oxopropyl phosphate binding" evidence="2">
        <location>
            <begin position="212"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="43"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="70"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="190"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="7"/>
        </location>
        <ligand>
            <name>3-amino-2-oxopropyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57279"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="18"/>
        </location>
        <ligand>
            <name>3-amino-2-oxopropyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57279"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>1-deoxy-D-xylulose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57792"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>1-deoxy-D-xylulose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57792"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>1-deoxy-D-xylulose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57792"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="191"/>
        </location>
        <ligand>
            <name>3-amino-2-oxopropyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57279"/>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="2">
        <location>
            <position position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="244" mass="26500" checksum="27C5C5636BABCAD6" modified="2019-10-16" version="1">MVELGVNIDHVATVRQARRTYEPDPVAAAYLAELGGADGITFHLREDRRHIQDRDVRILKETISVHVNMEFGCVREIVDIACDVKPDWALLVPESREEVTTEGGLNVAEDSSRAADAIKQLHDAGIAVSLFLDPDLRQIESAAALGVGAVELHTGPYALAKGEAVERELQRLKTCGQAVLDAGMRLHAGHGLTYKNVHPVAAIPHIRELNIGHSIIARAVMVGIQKAVADMKHEIEVATRAKSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRM9</accession>
    <name>A0A518IRM9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_17350</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="148"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="180"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="211"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="256" mass="26459" checksum="83B228CC9AAB99F8" modified="2019-10-16" version="1">MNASCEQSSATRGSSAVARWSIAALLSAAVAWTLVNFTPIQFRLPPELRSVDMYSPPELQAQQKELVPITLWRTCIAELTFAGLSLGGVSTLLIAGAGTRSRLRFVAVGIFTGLAFGFLAGQIGWTLRAALATGSLSTLSSDPIVRETLLYFVVSLTLGCPLAIAYYLASGKQAGQGAIAVLLACGLAGAIVPIAAAPFPNMLTHHFPPEGLGLSGIWFGLIGCLASLLPNAIGSKAKDVSLATVAESTSQPAGEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRQ8</accession>
    <name>A0A518IRQ8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Signal transduction histidine-protein kinase BarA</fullName>
            <ecNumber evidence="13">2.7.13.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">barA_2</name>
        <name evidence="13" type="ORF">Mal33_17120</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="13"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036641">
        <property type="entry name" value="HPT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
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        <property type="entry name" value="PAS-like_dom_sf"/>
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        <property type="entry name" value="PAS_4"/>
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    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008207">
        <property type="entry name" value="Sig_transdc_His_kin_Hpt_dom"/>
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    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
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        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01627">
        <property type="entry name" value="Hpt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47226">
        <property type="entry name" value="SSF47226"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50894">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="13" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PAS" evidence="10">
        <location>
            <begin position="13"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="10">
        <location>
            <begin position="155"/>
            <end position="210"/>
        </location>
    </feature>
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        <location>
            <begin position="210"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="11">
        <location>
            <begin position="338"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="10">
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            <end position="449"/>
        </location>
    </feature>
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        <location>
            <begin position="469"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="8">
        <location>
            <begin position="539"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="9">
        <location>
            <begin position="780"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="9">
        <location>
            <begin position="924"/>
            <end position="1042"/>
        </location>
    </feature>
    <feature type="domain" description="HPt" evidence="12">
        <location>
            <begin position="1113"/>
            <end position="1211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1046"/>
            <end position="1079"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="1052"/>
            <end position="1066"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="6">
        <location>
            <position position="834"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="6">
        <location>
            <position position="973"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphohistidine" evidence="5">
        <location>
            <position position="1152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
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    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
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    </evidence>
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        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
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    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
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    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="QDV55733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1211" mass="133870" checksum="8E5BC8B89AE2422A" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRR6</accession>
    <name>A0A518IRR6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Chaperone protein ClpB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">clpB_1</name>
        <name evidence="9" type="ORF">Mal33_17220</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
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    </reference>
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    </dbReference>
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        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
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        <property type="entry name" value="ATPase_T6SS_ClpV1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036628">
        <property type="entry name" value="Clp_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004176">
        <property type="entry name" value="Clp_R_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001270">
        <property type="entry name" value="ClpA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018368">
        <property type="entry name" value="ClpA/B_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041546">
        <property type="entry name" value="ClpA/ClpB_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17871">
        <property type="entry name" value="AAA_lid_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02861">
        <property type="entry name" value="Clp_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00300">
        <property type="entry name" value="CLPPROTEASEA"/>
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    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="2"/>
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        <property type="entry name" value="SSF81923"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03345">
        <property type="entry name" value="VI_ClpV1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00870">
        <property type="entry name" value="CLPAB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="AAA" evidence="7">
        <location>
            <begin position="227"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="domain" description="AAA" evidence="7">
        <location>
            <begin position="639"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="domain" description="ClpB_D2-small" evidence="8">
        <location>
            <begin position="810"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="167"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="916"/>
            <end position="941"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="441"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="167"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV55743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="941" mass="102558" checksum="87E9FCFD42F4A5E1" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRT6</accession>
    <name>A0A518IRT6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Glucose-1-phosphate adenylyltransferase</fullName>
            <ecNumber evidence="8">2.7.7.27</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">glgC_2</name>
        <name evidence="8" type="ORF">Mal33_17420</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="6">Glycan biosynthesis; glycogen biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.27" evidence="8"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00164"/>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008878">
        <property type="term" value="F:glucose-1-phosphate adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005978">
        <property type="term" value="P:glycogen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011831">
        <property type="entry name" value="ADP-Glc_PPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005836">
        <property type="entry name" value="ADP_Glu_pyroP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43523">
        <property type="entry name" value="PTHR43523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02091">
        <property type="entry name" value="glgC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00808">
        <property type="entry name" value="ADP_GLC_PYROPHOSPH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00809">
        <property type="entry name" value="ADP_GLC_PYROPHOSPH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00810">
        <property type="entry name" value="ADP_GLC_PYROPHOSPH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0320">Glycogen biosynthesis</keyword>
    <keyword evidence="2" id="KW-0321">Glycogen metabolism</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transferase" evidence="7">
        <location>
            <begin position="6"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV55763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="430" mass="47403" checksum="6998F8389E292F17" modified="2019-10-16" version="1">MRNTIALILGGGRGTRLFPLTKIRAKPAVPLAAKYRLIDIPISNCISSGVNKIYCLTQFLSVSLHRHIRQTYSFDNFNGGFVELLAAQQTEGSGEDWYEGTADAVRKNLSYIQQDFVEHVLILSGDQLYRMDYGDMMKTHIESGADVTIAGIPVSRDDAHALGVMRVDDSGRVVGFLEKPQTPEEIDMVKMDPAWLDKQGIPSHGRDCVASMGLYIFNRDTLVDFLQKTQYQDFGREVFPAAIRSRKVQLHLFDGYWEDIGTIKAFYECNLSLAQRTPPYNFNDSESPVYSRPRFLPPTFMEGAQVTGSLIADGCRIEKGAVIENSVVGLRCIIGEGVVIKDSIIMGADDYESSTRQQTAAAQGKPPVGIGAGSVVQGAILDKNCRVGKNVRIVNDSNVQESDTHEECPVRDGIPIVCKNASLPDGWKLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISH1</accession>
    <name>A0A518ISH1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Serine/threonine-protein phosphatase 1</fullName>
            <ecNumber evidence="2">3.1.3.16</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">pphA_2</name>
        <name evidence="2" type="ORF">Mal33_19990</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.3.16" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017018">
        <property type="term" value="F:myosin phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos" evidence="1">
        <location>
            <begin position="4"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="219" mass="24692" checksum="BC021242C3AEC2C3" modified="2019-10-16" version="1">MPERLIAIGDIHGCSDALQTLIKAIDPTPDDTLVVLGDVVDRGSATRQAVDMLLEIAQQSQLIALQGNHEEMMLRVLDGESPQRWLQFGGIDTLDSYGFTGDFSAIPESHHAFYHGMLDYYETDGYFFTHAAYKHDLPLEYQPVELLRWHSLREGLPPAHENGKICFVGHTAHKEGEIMDFGHIVCLDTYCYGGRWLTAMDVRTRQTWQSDPAGQLRTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISJ2</accession>
    <name>A0A518ISJ2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Type II secretion system protein F</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">gspF_1</name>
        <name evidence="9" type="ORF">Mal33_20460</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GSP F family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.81.30">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003004">
        <property type="entry name" value="GspF/PilC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018076">
        <property type="entry name" value="T2SS_GspF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042094">
        <property type="entry name" value="T2SS_GspF_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30012">
        <property type="entry name" value="PTHR30012"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00482">
        <property type="entry name" value="T2SSF"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00812">
        <property type="entry name" value="BCTERIALGSPF"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="174"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="216"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="341"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="380"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="451"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="domain" description="T2SSF" evidence="8">
        <location>
            <begin position="74"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="T2SSF" evidence="8">
        <location>
            <begin position="278"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="domain" description="T2SSF" evidence="8">
        <location>
            <begin position="370"/>
            <end position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV56067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="479" mass="52817" checksum="FD72F6C70FE607FD" modified="2019-10-16" version="1">MPIYLFEAMDATGQEIRDEIDAQNEEEAQTTIRQMGYFVTKISVKKQAAKAAAAKKRRGGGGFGGAKTKHIAMFTRQLSILQDSGLPILRSLKILEANQKPGKLKNALLDTCEEIESGSTMSESMAKSPKVFNRLYVNMIKAGEAGGALETILQRLADFMERAESLKRKVKGALIYPCVVVFVACAIVTFIMIKIVPTFEQMFEEFDLELPAPTLLLIALSNYIVRYGFLIVVIPVCMFIIVKLIRKFKQGRMGFDMFIIKAPIFGGLLEKNILARTTRTLGTLVSSGVPILEALNITRETSGNAMFERLFAKVTESIRQGEVISKPLAENSTPGFHPMAAFFWAFLGAFPGIMLMSVALTANYTKLGENPEMVQTLRSIAFGGTAGGCTFAVLWYLMKMKERVVDDLVVNMVDVGEETGELDTMLYKVADTYDEEVRVMTDGMMALMEPLLIVFLGLVVGFIVVSLFMPLVSLISSLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISQ7</accession>
    <name>A0A518ISQ7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_21060</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="73"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="95" mass="10845" checksum="32721E717655178C" modified="2019-10-16" version="1">MKFTRNHYFLIGILLILFGIQFRLVDSFVINERCTRALDRVMRKTPVASNDAFSAFAMQVHPNPTKRVQPPRWIGAAMVVSGIVVTLHSFALRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IT59</accession>
    <name>A0A518IT59_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_22640</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="313" mass="35618" checksum="04FCB29A1E6CC9F4" modified="2019-10-16" version="1">MITQSHTNGTIAFGQPTHEELLESFERKVQLIRDRVVSVAHGYHSGCYIVGRPGTSKTFTVKEELDRLEAPSTLQNARMTPMGLFSYIAEHPEHVIVLDDIPSLFKNDQAMQILMAALDGKPGQPRKVSYKSKDQDIHVLFSGAIIAISNLPLRRDPLAQALGSRVVMLEHEPTDEEIAAFMQHLAAKGHADLSSEECLEVVQFVIAETRSYDMRLDLRHLNKAWQDFRQDKHGRSKTPWKDLVRTSLQKIASEPILSMSKRDDIELQRQKVRDAIRKFPNDRQAQLEYSGLKQSTFYNRRKEVLAEAEFIAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IT70</accession>
    <name>A0A518IT70_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_22520</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="208" mass="23379" checksum="AD3E9AA42556E00A" modified="2019-10-16" version="1">MKQLSGWRCSIQIARGKNRVAKARMTGSLQQQFDSQQFPNDYQLVNGVAMHAENPECFHIPPNVIKRHISPGQFVELRIDSPRFSVHEDASEKCSCPSCNGELTKPILKHSHPASLVPLPNQNVISRGWGEDFWVKVEQRSGGLFKGTVDNPLVETRLHGLKQSDEMIFNEDHILAVHDIHRQQLVAGMEVADLKELAQWVASLRGDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IT87</accession>
    <name>A0A518IT87_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_22880</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="110" mass="11774" checksum="29DB857B3533C751" modified="2019-10-16" version="1">MRGLVICTALIGLTLLGGCRICGSEDDCAYPAFGGSWERTNRNHGRVGSIFAPAGHKVAGGESPQPIFLQQPESQPSRPTDIDAPSLLDDLETDMPELQQPEPLGDIDRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITD8</accession>
    <name>A0A518ITD8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Colicin uptake protein TolQ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Mal33_23410</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the exbB/tolQ family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002898">
        <property type="entry name" value="MotA_ExbB_proton_chnl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01618">
        <property type="entry name" value="MotA_ExbB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="114"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="217"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="258"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="domain" description="MotA_ExbB" evidence="9">
        <location>
            <begin position="183"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="53"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="53"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV56355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="326" mass="34402" checksum="65DB60C214BA3E19" modified="2019-10-16" version="1" precursor="true">MLASHAAPNQAPRCATTAAAQPTAARWFTALAMMLAFAFSVPGTAAAQQFRQPGQSFQQQGFGQQGGFAPQPTAIPSIPPAAQPQPTGEAPAEEADEESSSWVPGWASSLKSQISAGGLLMIPLGICSLIVIGLICERLISLRRGRVIPRPFVRRFREKLDDGQLDIEEANEVCNEFDCAVADVFIAAVKRTGRPMVEIEAAVFDALERTADGLRRYLRVFHAVSNVAPLIGLLGTVLGMIDAFETMASEAGAGHPELLAVGISQALVTTAGGLSVAIPAYLAYMYFSSRADGYLAEIERLSLGVIDAVSAESGGAASKTRRRKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITE3</accession>
    <name>A0A518ITE3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">AP-4-A phosphorylase</fullName>
            <ecNumber evidence="5">2.7.7.53</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_23440</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.7.53" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003877">
        <property type="term" value="F:ATP adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06529">
        <property type="entry name" value="S24_LexA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019808">
        <property type="entry name" value="Histidine_triad_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011146">
        <property type="entry name" value="HIT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039418">
        <property type="entry name" value="LexA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036286">
        <property type="entry name" value="LexA/Signal_pep-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015927">
        <property type="entry name" value="Peptidase_S24_S26A/B/C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025202">
        <property type="entry name" value="PLD-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01230">
        <property type="entry name" value="HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00717">
        <property type="entry name" value="Peptidase_S24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13091">
        <property type="entry name" value="PLDc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51306">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF54197"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HIT" evidence="2">
        <location>
            <begin position="1"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="3">
        <location>
            <begin position="356"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="4">
        <location>
            <begin position="566"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Histidine triad motif" evidence="1">
        <location>
            <begin position="94"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV56358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1233" mass="137230" checksum="EBC2A20EBA31FE3A" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITG8</accession>
    <name>A0A518ITG8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Serine/threonine-protein kinase PknD</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">pknD_4</name>
        <name evidence="2" type="ORF">Mal33_23700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022178852" evidence="1">
        <location>
            <begin position="24"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="285" mass="30573" checksum="1928239349286239" modified="2019-10-16" version="1" precursor="true">MRFACTFAQVAALSVVLLGGLSAEETVDEETPSRPKYPLAIAVDAAEAYVVDLDLPGVWKLSAEGQPTLFVRGSKWIRKPLNRPRCVAILPDGDLLIGDTPTREVYRIAAAGGEPQPLTAGGIGIPMSIAVDADENVYVADLETRTIVRFPLAGGKVETFAQVNTRGLSLDPQGQLWAVTQDKDQLVRIDSAGKATPVVSDRPFQFPHNVVVTDSGDAFVTDGYAKAVWRIPAGGKPEQWLTGPPLINPVGLAIQEGNLFVADPHAKNIYKIAIDSKQITPLIKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITQ2</accession>
    <name>A0A518ITQ2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_24570</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="211" mass="23723" checksum="7EB2D7C07EA9E46B" modified="2019-10-16" version="1">MESKIEATRRLKVDGRWDEASAAKDREKTRLVESGMTRRQAGPLAWEWMIENFPPLSAADKAWRDSLPLIKIERFSSELLTGDDAEGYSINDYWWVLRYLVAYDLCIQRNDAAAAIEIQQRLLDECTSKDQAVLATLAIADLPHFIHACEARVETSMFTLIDAVGSSGLEIDALAHFYDTLSPMGVRLEAFQAESWGDLAASGKYRELFAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITQ9</accession>
    <name>A0A518ITQ9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Arylsulfatase</fullName>
            <ecNumber evidence="8">3.1.6.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">atsA_19</name>
        <name evidence="8" type="ORF">Mal33_24400</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="PTM">
        <text evidence="4">The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.</text>
    </comment>
    <dbReference type="EC" id="3.1.6.1" evidence="8"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004065">
        <property type="term" value="F:arylsulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013427">
        <property type="entry name" value="Haem-bd_dom_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013428">
        <property type="entry name" value="Membrane-bound_put_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004155">
        <property type="entry name" value="PBS_lyase_HEAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011041">
        <property type="entry name" value="Quinoprot_gluc/sorb_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00034">
        <property type="entry name" value="Cytochrom_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00567">
        <property type="entry name" value="EZ_HEAT"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50952">
        <property type="entry name" value="SSF50952"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02603">
        <property type="entry name" value="CxxCH_TIGR02603"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02604">
        <property type="entry name" value="Piru_Ver_Nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0349">Heme</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021880343" evidence="6">
        <location>
            <begin position="22"/>
            <end position="1496"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="7">
        <location>
            <begin position="1350"/>
            <end position="1496"/>
        </location>
    </feature>
    <feature type="modified residue" description="3-oxoalanine (Cys)" evidence="4">
        <location>
            <position position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR600917-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV56450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1496" mass="162120" checksum="85705338C3778B73" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IU11</accession>
    <name>A0A518IU11_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_25670</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010496">
        <property type="entry name" value="3-keto-disaccharide_hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06439">
        <property type="entry name" value="DUF1080"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1080" evidence="2">
        <location>
            <begin position="86"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1080" evidence="2">
        <location>
            <begin position="267"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="443"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="445"/>
            <end position="528"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="528" mass="58179" checksum="5C7C06540FDA32E8" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IU50</accession>
    <name>A0A518IU50_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_25940</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="355"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="432" mass="48237" checksum="BA66A34C35558ACE" modified="2019-10-16" version="1">MASGTVFYVGTDSEVAHHAAPLMGRLPIRIATAEEVLKLAVPGDLAIFFSEHFERFRSAIRQLQSRRVATLYAIDGILEWRNAWENRADEPASPWTMRPVLSDKIACIGAAQARVLSSWGNADKIEIVGIPRFDDLAARDTTRNLPRDPNVFRILVMTARCPGFTDSQRQQIAQSLADLRDMVRETDRLDGRRIEIAWRLTGGMDHRIGVDNQESDSDLADVLDRVDATITTPSTAQLESMLLGKPTAILDYTNSPLYADAAWRITAKQQIAQTLEQLIRPTEARMHYQKSVLHDALQLQTPASDLMVQLIQAMLGQAQNAIRSDRTPRFPEAILPPVDAAPPSLCLPAAYPTRGVFQNDDLQKLQTQLADAERETELLHRMIDGLRDELGQAHAIFDSIHRHPVAGPVVRARQKVIDWFAKAQRGDAEHDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IU62</accession>
    <name>A0A518IU62_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">cph1</name>
        <name evidence="9" type="ORF">Mal33_26110</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032255">
        <property type="entry name" value="HBM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01358">
        <property type="entry name" value="HBM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="14"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="8">
        <location>
            <begin position="322"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="407"/>
            <end position="618"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV56619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="633" mass="70993" checksum="6363B4B77115076E" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IU87</accession>
    <name>A0A518IU87_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphate-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">pstS_2</name>
        <name evidence="6" type="ORF">Mal33_26400</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Involved in the system for phosphate transport across the cytoplasmic membrane.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the PstS family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042301">
        <property type="term" value="F:phosphate ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006817">
        <property type="term" value="P:phosphate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024370">
        <property type="entry name" value="PBP_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011862">
        <property type="entry name" value="Phos-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12849">
        <property type="entry name" value="PBP_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02136">
        <property type="entry name" value="ptsS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2 4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PBP_domain" evidence="5">
        <location>
            <begin position="46"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF12849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV56647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="358" mass="39025" checksum="645DAC661881007A" modified="2019-10-16" version="1">MRQTLGRTTLTAMLCIGFLTVAGCGSKKSGGDSDAGGPVVSDGEAVSQLTGKIAVEGSSTVSPITTQAKERFNEQHPDVTISITGEGTSNGFKSFAKKETDIQDASRPIKQKELDTCNESGLEFIEVPVAYDGLTIAVHPKNKFVKSLTVDQLKKIFRSGDSAKTWKEVDPQWPDKKISIFSPGTGSGTYDYFSEVVIGKEGSLRDDNQINLNEDDNILVRGVAGDEFAIGYFGYSYYDRNKNDLQAVPIINPAGEAVLPNAETIESGEYAPFSRPLFIYLNSESLDKVEVEIFVESYMTNIREIVAAANYVPLPESVYTAATQNIENRVAGTHYLTAEGEKREGSIINVFKPENLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUC2</accession>
    <name>A0A518IUC2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">TspO/MBR family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Mal33_26810</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TspO/BZRP family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15904">
        <property type="entry name" value="TSPO_MBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038330">
        <property type="entry name" value="TspO/MBR-related_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004307">
        <property type="entry name" value="TspO_MBR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10057">
        <property type="entry name" value="PTHR10057"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03073">
        <property type="entry name" value="TspO_MBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005859">
        <property type="entry name" value="PBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="49"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="78"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="110"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV56683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="130" mass="15165" checksum="41543FAFAF241EBB" modified="2019-10-16" version="1">MTWIEWYNGLDKPSWTPAPGTIGLIWQLLYPVIIVTFGFVFVQAFRKRLPWLVALPFAINLVANLCFTPIQFGLRNLPLAAVDILIVWTTILWMMFAIWKHYRWVAMAQIPYLIWVSIATTLQLAITWNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUD8</accession>
    <name>A0A518IUD8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hpt domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_26860</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036641">
        <property type="entry name" value="HPT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008207">
        <property type="entry name" value="Sig_transdc_His_kin_Hpt_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01627">
        <property type="entry name" value="Hpt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47226">
        <property type="entry name" value="SSF47226"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HPt" evidence="1">
        <location>
            <begin position="34"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="119" mass="13422" checksum="17E282C6DA10B7D5" modified="2019-10-16" version="1">MSELPKDDKPWIDRLGECTGNHHESMVAVAEGLVMELPDVSQRLRVAIAGGTPKEIERYGHTLKSCLKYVSSGDEVALAEEIERCGRESRVSDAVALYDQLQPTVQAWQDRVQQWLDRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUJ1</accession>
    <name>A0A518IUJ1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Large cysteine-rich periplasmic protein OmcB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">omcB_2</name>
        <name evidence="3" type="ORF">Mal33_27520</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001434">
        <property type="entry name" value="DUF11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01345">
        <property type="entry name" value="DUF11"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01451">
        <property type="entry name" value="B_ant_repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF11" evidence="2">
        <location>
            <begin position="370"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="domain" description="DUF11" evidence="2">
        <location>
            <begin position="592"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="domain" description="DUF11" evidence="2">
        <location>
            <begin position="705"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="266"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="276"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="332"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="814" mass="84751" checksum="76819BD31CF1085C" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IV26</accession>
    <name>A0A518IV26_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_29440</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
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    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="285" mass="29608" checksum="B678D591E7A7E773" modified="2019-10-16" version="1">MSVRTVFHSAIVSTATFGLLICGFQPAMGVERRDSGQDDVRRVELFEAMKNGDIEVKFVPRDAARANLLVENKTKKPLHIQLPDAFAAVPVQAQFGGGMGGGGMGGMGGGGMGGMGGGMGGGMAQGMGGGMGGMGGGGMGGMGGGGMGGMGGGGGFMRVAAEKRHKVALTTVCLEHGKPDPNPKIPYTIIPIEQFTQDPSVIELCTHLGYGRVPQNTAQAAAWHLMDKMSWQELASKNRRESAYTGNTPFFNGNELRAAMSVVQYVSKDEPAVQVSLADDYTSAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IV62</accession>
    <name>A0A518IV62_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_29800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011453">
        <property type="entry name" value="DUF1559"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07596">
        <property type="entry name" value="SBP_bac_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="372" mass="40617" checksum="5AC98B9843A43F70" modified="2019-10-16" version="1">MKRYVLKGPRVGFTLVELLVVIAIIGILVGLLLPAVQAAREAARRMQCSNNLKQIGLATHNFHDTYDALPPLVTHAGGPTFFFHILPYVEQAALYDMYAGGVSSGSNTTSLDREFDSPGVLGNYEIIKAAGREQDIQGITAYHCPSYRVASVERQEAGGANDRSRGPRGDYAVVFTQGRGDNTTLDYSSTEDGWWGHMDATNNGSRGRQKGIIKTADAAGLPDTDPSAEIDTRRTKAKFSQKLNSIKDGTSNTAMVGEKFWRRDEWDRRCCAGDRVDGSIFVANGSWREYNVARNMRLPFRMGIEDHLDGSWVEDNPDSNVAARGAGFGSYHAGSVQFVMGDGAVKGFSPTMDTFVRFKLADRADGQSVSIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVT4</accession>
    <name>A0A518IVT4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_32030</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="53"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="141"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="323"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="432"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="202"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="459"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="522"/>
            <end position="542"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV57201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="555" mass="61598" checksum="3BC3D69F650A487C" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVT6</accession>
    <name>A0A518IVT6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_31910</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011453">
        <property type="entry name" value="DUF1559"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027558">
        <property type="entry name" value="Pre_pil_HX9DG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07596">
        <property type="entry name" value="SBP_bac_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04294">
        <property type="entry name" value="pre_pil_HX9DG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="296" mass="32148" checksum="29E47ED6884AD4CE" modified="2019-10-16" version="1">MDARRQGLTVLELLVVIAVISIMAALLLPALMSARESARRVACRSHLRELGIAAHHFHDGFGHLPRAWKATDDGKPFAFAWAANMLPQLGQQNMLAQLDLGTSPTGLTTSVAAEAFAYELFVCPSDLTEPSFELQVDTERDDDVDGSTDNALHAAASPNLGWFPTANYVGVYGTHEADDYEEAAPTSGFADGSIINEQDIRFRDLRRGLSNTMIVGERTMAAVPSTWLGIDLRGGDAPCRLVGSAMTQPNCETCDECEFSSRHPGGSNFLWGDGRVTLVSESIDSVLYQENSRRMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IW34</accession>
    <name>A0A518IW34_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">2Fe-2S ferredoxin-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_33000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="1">
        <location>
            <begin position="2"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="124" mass="13482" checksum="E2E9E1C43FD15DD8" modified="2019-10-16" version="1">MPSIRYSNRTLSCDVGENLRKVLLRSKAPVYNGVARIVNCRGNGICGMCTVRLRGSVSWSSTYENALLRLIPGANSLGLRLACLCTVHGDVAVEKFGGTWGTDCDSQRHFGRKATSGDLPNQQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IW44</accession>
    <name>A0A518IW44_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_33120</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010869">
        <property type="entry name" value="DUF1501"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07394">
        <property type="entry name" value="DUF1501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="439" mass="48059" checksum="4A44809A05D86C48" modified="2019-10-16" version="1">MKHTHKTCGSPEHLLHRRLFLQGTMAASAASVASFNGLFSVPALADETKRRGKKCILLWLCGAPSQFETWDPKPGTPFSGPFGAIPTNLPGVQISSLMPKCAGIMDKLAVIRSMSTEPGEHFQGIDVLTRGDKPRQPFVRPILGSVVAEQLGHLDSPVPQFILLDPCPEGNEFKGFKAGNWAGWLGAQYGPVRAGGEYSIPNLNKLDTISDIDHQDREALRSFFSKKYENDRRSQAAGSLNAAFDRVKGLMSCAPLFDLNSLPEADRQRYGAGAFAQHALQARHLIENGSTFVMVANGMPWDNHVFQHEMHQMLVPELDNVLYQLVTDLEDRGMLEDTLVIAMGEFGRSPWLNAARGRDHYPKAWSLAMAGGGIRGGVVHGATDPLGHEVAEDAVDNRQLFATIFAALGIDPREEYDLPDLPTFSRVEDGVAPIEQLLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IW52</accession>
    <name>A0A518IW52_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_33280</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="201" mass="22588" checksum="C008B099A407B63B" modified="2019-10-16" version="1">MDWQPFAALNLLRNPFGELTREDRVRAAVVDVADCIDRLQQPQTALQFIADCGRGKTTHLLSIAAQAPAAAYVYLPEDERCPPIPHGQPLLIDEAQRLPWLVRRRAFARGGALVLGTHVDLTGPLRRAGYSVWTYHVGQDLTAERLAQMLNRRIQLAQLRSGPIPQISETEAADWMVRHGSDIRAIEFDLYERFQQQIGVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IW85</accession>
    <name>A0A518IW85_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter ATP-binding protein</fullName>
            <ecNumber evidence="5">3.6.3.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_33500</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.6.3.-" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
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    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
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        <property type="entry name" value="ABC_transporter-like_CS"/>
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        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
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        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
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        <property type="entry name" value="ABC_tran"/>
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        <property type="match status" value="1"/>
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    </dbReference>
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        <location>
            <begin position="2"/>
            <end position="244"/>
        </location>
    </feature>
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        <location>
            <begin position="42"/>
            <end position="49"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV57346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="250" mass="27873" checksum="3B8A5A8F7AB03634" modified="2019-10-16" version="1">MVRLATSIRELKKEYVLKSETVRALRGVSFDVPEGDYVAIMGPSGSGKSTLLNMLGCLDKPSSGQLLLGDDDISRMTDDKLAEVRSRRIGFVFQSYNLIQQLTVVENIQVPLYYQGRLGPKERQRCVELAGLVGLRDRLDHRPTQLSGGQQQRVAIARSLVNDPYFILADEPTGNLDSRTTAEILAMFDQLNNEGRTIILVTHEDDVAERARRVVRLKDGLLCSDVQNSEENREKARQASLAAAEAVRDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWC8</accession>
    <name>A0A518IWC8_9BACT</name>
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        <submittedName>
            <fullName evidence="4">FG-GAP repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_33970</name>
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    <organism evidence="4 5">
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        <dbReference type="NCBI Taxonomy" id="2527990"/>
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            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Pirellulaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
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                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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    <keyword evidence="1" id="KW-0732">Signal</keyword>
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        <location>
            <begin position="504"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="39"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="39"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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            <dbReference type="Pfam" id="PF07593"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="QDV57387.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="587" mass="63704" checksum="0D81E4135F097997" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
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    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
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                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140658">
        <property type="term" value="F:ATP-dependent chromatin remodeler activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013663">
        <property type="entry name" value="Helicase_SWF/SNF/SWI_bac"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SNF2-rel_dom"/>
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    </dbReference>
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        <property type="entry name" value="SNF2_assoc"/>
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    </dbReference>
    <dbReference type="Pfam" id="PF04434">
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="51"/>
            <end position="91"/>
        </location>
    </feature>
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        <location>
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            <end position="837"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="4">
        <location>
            <begin position="958"/>
            <end position="1106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50966"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV57408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1119" mass="125736" checksum="C8A4C78003EF2D1A" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWD6</accession>
    <name>A0A518IWD6_9BACT</name>
    <protein>
        <recommendedName>
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            <ecNumber evidence="3 4">5.4.99.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">5-(carboxyamino)imidazole ribonucleotide mutase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 7" type="primary">purE</name>
        <name evidence="7" type="ORF">Mal33_34220</name>
    </gene>
    <organism evidence="7 8">
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        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetia</taxon>
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            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 4">Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 4">
            <text>5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole + H(+) = 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate</text>
            <dbReference type="Rhea" id="RHEA:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58730"/>
            <dbReference type="ChEBI" id="CHEBI:77657"/>
            <dbReference type="EC" id="5.4.99.18"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 4">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate from 5-amino-1-(5-phospho-D-ribosyl)imidazole (N5-CAIR route): step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the AIR carboxylase family. Class I subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.18" evidence="3 4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00943"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034023">
        <property type="term" value="F:5-(carboxyamino)imidazole ribonucleotide mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01929">
        <property type="entry name" value="PurE_classI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033747">
        <property type="entry name" value="PurE_ClassI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000031">
        <property type="entry name" value="PurE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024694">
        <property type="entry name" value="PurE_prokaryotes"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00731">
        <property type="entry name" value="AIRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001338">
        <property type="entry name" value="AIR_carboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01001">
        <property type="entry name" value="AIRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01162">
        <property type="entry name" value="purE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="1 3 4" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AIRC" evidence="6">
        <location>
            <begin position="6"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3 5">
        <location>
            <position position="14"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3 5">
        <location>
            <position position="17"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3 5">
        <location>
            <position position="44"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR001338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001338-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV57412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="173" mass="18150" checksum="6558A3859FAEB76B" modified="2019-10-16" version="1">MADPSPTVGVIMGSKSDWETMRHADAMLSALQIPHECKVVSAHRTPQRMFEYAQMAADRGIQVIIAGAGGAAHLPGMVASETLLPVLGVPVQSRALQGLDSLLSIVQMPGGVPVGTLSIGTSGAKNAALMAARILSLTDPALQQRLADFVAQQTADVLEDAEIENADLEDLQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWJ2</accession>
    <name>A0A518IWJ2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 10">Vitamin B12-dependent ribonucleotide reductase</fullName>
            <ecNumber evidence="4 10">1.17.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">nrdJ</name>
        <name evidence="14" type="ORF">Mal33_34710</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 10">Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>[thioredoxin]-disulfide + a 2'-deoxyribonucleoside 5'-diphosphate + H2O = [thioredoxin]-dithiol + a ribonucleoside 5'-diphosphate</text>
            <dbReference type="Rhea" id="RHEA:23252"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57930"/>
            <dbReference type="ChEBI" id="CHEBI:73316"/>
            <dbReference type="EC" id="1.17.4.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 10">
            <name>adenosylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the ribonucleoside diphosphate reductase class-2 family.</text>
    </comment>
    <dbReference type="EC" id="1.17.4.1" evidence="4 10"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050897">
        <property type="term" value="F:cobalt ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004748">
        <property type="term" value="F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071897">
        <property type="term" value="P:DNA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02888">
        <property type="entry name" value="RNR_II_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013678">
        <property type="entry name" value="RNR_2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000788">
        <property type="entry name" value="RNR_lg_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013344">
        <property type="entry name" value="RNR_NrdJ/NrdZ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08471">
        <property type="entry name" value="Ribonuc_red_2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02867">
        <property type="entry name" value="Ribonuc_red_lgC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01183">
        <property type="entry name" value="RIBORDTASEM1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02504">
        <property type="entry name" value="NrdJ_Z"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0846">Cobalamin</keyword>
    <keyword evidence="8 10" id="KW-0170">Cobalt</keyword>
    <keyword evidence="7 10" id="KW-0237">DNA synthesis</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ribonuc_red_2_N" evidence="13">
        <location>
            <begin position="65"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="RIBORED_LARGE" evidence="12">
        <location>
            <begin position="197"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="892"/>
            <end position="935"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="895"/>
            <end position="912"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00014409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU364064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF08471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="QDV57461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1017" mass="111396" checksum="9D483BCA944A50CD" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWT1</accession>
    <name>A0A518IWT1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_35590</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="104" mass="11940" checksum="E9533C5355CB9F25" modified="2019-10-16" version="1">MAHYDDLDNKQIYAYSAIFVVGTVITIFFVSIIFHWMDNGEQTRKMLETEYNQFNQILAEQTESLNEFVVVDPVTGRFGIPIENAIDSALKQEKKSDEGTRDEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IX97</accession>
    <name>A0A518IX97_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_37240</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="71" mass="8038" checksum="1AAE0EDE36BD9041" modified="2019-10-16" version="1">MLEVKGDPVTEPLENEEMEALRNQIWDFVYRAGNPQTINSIVDDLHLSDDSVREAVHHAWFVCEGDTVAIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXA2</accession>
    <name>A0A518IXA2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">SET domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Mal33_37230</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003616">
        <property type="entry name" value="Post-SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SSF82199"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="POST_SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SET" evidence="4">
        <location>
            <begin position="16"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="Post-SET" evidence="5">
        <location>
            <begin position="126"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV57710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="158" mass="17566" checksum="5A16E1CB0B5F63CC" modified="2019-10-16" version="1">MLNSETSPTTDCESDPAVNVQSTPIGKGVFADREFRAHDVIGWITGKIHDDPEYGSEYCIDIGGTATLEPDAPFRFLNHCCEPNSQFTWDELEEDSDAIPEVYLLALRDIEAGEQLTIDYNWAADCAIPCHCGAETCRGWIVTLDEIDQLPAKKQQAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXQ8</accession>
    <name>A0A518IXQ8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transglutaminase-like superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_38850</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002931">
        <property type="entry name" value="Transglutaminase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01841">
        <property type="entry name" value="Transglut_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TGc" evidence="2">
        <location>
            <begin position="204"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="348" mass="39587" checksum="3C0C81BE2B1DB09B" modified="2019-10-16" version="1">MKSSIDPRRQSDARRSMARDDRRSFPIAPLSITRRTMLLSGAACCASPLLAQESSSPVADTRLEYVGPEKQLWQVGVKVMTAGSSCEEIFATFPVPTDWPEQTVQLVDQQISRYVDRWDTRDLFGGAKQVRVRMVNVPANTASDALFTFEVTKTRIQGVGETSDLVVPQKVEREERVFLGSSPYIDPRHGKIRKIAAEFESTPDQTPWQQVEQIYDWVREHVEYREGDIKSAVEALDDGHGDCEELTSLFVALCRAKKIPARMVWIPGHCYPEFMLHDPEGVPHWFPCQAAGTRQFGEMDEYKPILQKGDRFKVPEQKALQRYVAEFCKVKARSKPDVTFVRELTDSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IY00</accession>
    <name>A0A518IY00_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator NanR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_39810</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011711">
        <property type="entry name" value="GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008920">
        <property type="entry name" value="TF_FadR/GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07729">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00895">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48008">
        <property type="entry name" value="SSF48008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="4">
        <location>
            <begin position="13"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV57965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="223" mass="24863" checksum="670F73786201544A" modified="2019-10-16" version="1">MITEKKPQPLVLLNASGKCYSVLRKMLVCGQIPAGSRLAEVEWSQRLGSQRAALREAMVLLTHDGLLIRRPTGGFFVPTPEEVNYDSLWDARVVLELGALDLTFAPGAAPRNLAPLKKICSTMEDLHQAGLTMGFYESDFLFHQTLLELSGNEILAKMFAHSAQHFYPLAPVTDDIHKQNQAVVIQEHREIIAKLEAKQIKAASELLREHITRAKVAKAWTAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IY76</accession>
    <name>A0A518IY76_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FG-GAP repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_40630</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.130">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013517">
        <property type="entry name" value="FG-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028994">
        <property type="entry name" value="Integrin_alpha_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01839">
        <property type="entry name" value="FG-GAP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13517">
        <property type="entry name" value="FG-GAP_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69318">
        <property type="entry name" value="SSF69318"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021851809" evidence="2">
        <location>
            <begin position="28"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="406" mass="44816" checksum="F6F548E403047B37" modified="2019-10-16" version="1" precursor="true">MRITSRMIAFFASIGSVVASVPQTAMAESPASFQVRQLAVDANEGIATADVDGDGKLDLVAGRFWYKNPEWTPRPLRMIEDWNGYVQSNGDYIFDVNQDGRPDVVAGSFIPSEVFWFENPGDPSLKLGKMWNKHLLVDTGQSRNEGVLFEDLDGDGRPEWIANSWAKDVPMYVGLLKPKSEAAGEQAEKKDQKSEAAFSLVPTMIGKSGNGHGVGVGDLNGDGKTDILVGQGWYEQPAENPWSGEWKFHKVWDLHASLPMLIVDVDEDGRNDIIFGKGHDYGLLWWQNTGVDADGEIEFKEHLIDREFSQPHSLAWADLTGDGKPELITGKRYYAHNGNDPGGQEVPCMYYYTVDPKQAKFQRHTIDEGQVGTGLQIVVADFNQDGRNDIAVAGKSGTHLLTNVAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IY92</accession>
    <name>A0A518IY92_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_40670</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011453">
        <property type="entry name" value="DUF1559"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027558">
        <property type="entry name" value="Pre_pil_HX9DG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07596">
        <property type="entry name" value="SBP_bac_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04294">
        <property type="entry name" value="pre_pil_HX9DG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="337" mass="35852" checksum="E826894EAEC4B27C" modified="2019-10-16" version="1">MKLHKTRSAFTLVELLVVIAIIGILVGLLLPAVQAAREAARRMQCSNNLKQLGLALHNYHDTFKTFPPALLGSGRYNNASYHASNGGIKNTTGWALLLPFFEQSAIADQYDYNVCSSSSSPYGGVVAGDDTINDGLYNIPLDVLACPSDPSSGLVVSTSAGSTSMYSRREAIRTSYVFSVGSFTDYSGPWRSYSGDIRQGVFGNDGAANFAAMTDGTSTTIAIGEATGGAFKTSADYGPWGMTGTHTCCHGYLPGGSTTEVSTTYAAAYTQNYSINGAYNNDALGRTYAWVFSSKHPGGANFVFADGSVHLLTETMNYLTLQQLGYIHDGLPVPSDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYK7</accession>
    <name>A0A518IYK7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Macrolide export protein MacA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">macA_4</name>
        <name evidence="2" type="ORF">Mal33_41860</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="402" mass="43745" checksum="86AA4F19407A38D7" modified="2019-10-16" version="1">MKFSLKTFIWLTMFVALALASAFTLIPKPIAVEFATATIGPLRVTVQEDGKTRIREKYIVSAPVSGRISRIELDAGDHCDEKTLLAVILPSDPAILDSRARAEANARVLASEAALQRANSSAEQARINHELSQSKLERAETLLASRAISQEQYDVVRAESLAAAQAIKTASFDTEIARFELEMAEAAVDQFSDKQKESSAEPFEIYAPISGRVLRVFEESSTVVAVGTPLLELGDPSNLEIEIDVLSTDAVRIKPGAELMVEHWGGDTPLSGNVRVIEPGAFTKISSLGVEEQRVNIIADFNEPAERIASLGDGYRIEARITVKELSKALQIPNSALFRHQRKWHVLSIVDGKANLQPVQIGLQSESETEITDGLSTGDRVIVYPSDAIRPGTAVKPVPRVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYV5</accession>
    <name>A0A518IYV5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_42820</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007436">
        <property type="entry name" value="DUF485"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04341">
        <property type="entry name" value="DUF485"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="80" mass="8785" checksum="E002C64FE2D96D8B" modified="2019-10-16" version="1">MQSRNSRIGLILFFCYLLLYSGFVFINALSPDSMDMQPIEGINLAIVYGFVLIVGAFAMALLYGLLCKNEAPSDNDGEAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ17</accession>
    <name>A0A518IZ17_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Planctomycete cytochrome C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_43530</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011429">
        <property type="entry name" value="Cyt_c_Planctomycete-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011444">
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="PSCyt1"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PSD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022211171" evidence="1">
        <location>
            <begin position="20"/>
            <end position="914"/>
        </location>
    </feature>
    <feature type="domain" description="PSCyt1" evidence="4">
        <location>
            <begin position="37"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="domain" description="PSCyt2" evidence="2">
        <location>
            <begin position="164"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="domain" description="PSD1" evidence="3">
        <location>
            <begin position="639"/>
            <end position="890"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV58335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="914" mass="102156" checksum="5A5D0D99CCE30FA9" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ64</accession>
    <name>A0A518IZ64_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_43930</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011521">
        <property type="entry name" value="YTV"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07639">
        <property type="entry name" value="YTV"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="615" mass="68295" checksum="DD23969DE4364DF5" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ65</accession>
    <name>A0A518IZ65_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Bacterial type II secretion system protein F domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Mal33_43960</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018076">
        <property type="entry name" value="T2SS_GspF_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00482">
        <property type="entry name" value="T2SSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="113"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="141"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="290"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="domain" description="T2SSF" evidence="7">
        <location>
            <begin position="179"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV58378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="320" mass="34454" checksum="D83338A171D047CB" modified="2019-10-16" version="1">MFAADIQTTGFIVLGAIFVGVSAIAWLILGRVSGSDEKNRAEVRLDEMRQARRSGEGARGDTDVKKEALASVLNRAAPLANSLQPKDEVSQGKLKLRLMQAGFRNQGATTMFLTLKVISALVGLFIGGGVAVIFQGFTQDALLKLVISGGIMFFLPELALSWIISCRKQNIFLGLPDALDLMVVCVEAGLGLDQAMRKVSTEMGKTYKVIAEEFGVANAQLQLGRPRNEVLKALGNRSDVDDLKALASILIQADKFGSSIAQALRVQSDSMRVKRRQIAEEKAAKSAVKLIFPLVIFIFPGIFVVLVGPAAIAMIAQDSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZC7</accession>
    <name>A0A518IZC7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pyridoxamine 5'-phosphate oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_44620</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038725">
        <property type="entry name" value="YdaG_split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16242">
        <property type="entry name" value="Pyrid_ox_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyrid_ox_like" evidence="1">
        <location>
            <begin position="2"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF16242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="160" mass="17955" checksum="EB8E0F27E959A88C" modified="2019-10-16" version="1">MDTQQKLIDLVKEFDNAMLVTRSNDRTLDARPMAIAEVEEDGQIWFVTDRNSGKVADLMLDVEVAVTMQSGHKFVSISGTAEAVDDRAKLNELWKEAWKVWFPEGKASQAIVLLRIEPLHGQYWDNSGLQGVSYLIKAGKAYLQGERPKTDEATNAYVPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZD7</accession>
    <name>A0A518IZD7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Flagellin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">fliC</name>
        <name evidence="6" type="ORF">Mal33_44790</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Secreted</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Bacterial flagellum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the bacterial flagellin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009288">
        <property type="term" value="C:bacterial-type flagellum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001492">
        <property type="entry name" value="Flagellin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046358">
        <property type="entry name" value="Flagellin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042187">
        <property type="entry name" value="Flagellin_C_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010810">
        <property type="entry name" value="Flagellin_hook_IN_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001029">
        <property type="entry name" value="Flagellin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42792">
        <property type="entry name" value="PTHR42792"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00700">
        <property type="entry name" value="Flagellin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07196">
        <property type="entry name" value="Flagellin_IN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00669">
        <property type="entry name" value="Flagellin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00207">
        <property type="entry name" value="FLAGELLIN"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="6" id="KW-0966">Cell projection</keyword>
    <keyword evidence="6" id="KW-0969">Cilium</keyword>
    <keyword evidence="6" id="KW-0282">Flagellum</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Flagellin_N" evidence="4">
        <location>
            <begin position="4"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="Flagellin_C" evidence="5">
        <location>
            <begin position="860"/>
            <end position="944"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV58456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="945" mass="95134" checksum="EF39D50FB2A7AB89" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZE7</accession>
    <name>A0A518IZE7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">Protein GrpE</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">HSP-70 cofactor</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">grpE</name>
        <name evidence="8" type="ORF">Mal33_44890</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 4">Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3 5">Belongs to the GrpE family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000774">
        <property type="term" value="F:adenyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042803">
        <property type="term" value="F:protein homodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00446">
        <property type="entry name" value="GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.22.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.20.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01151">
        <property type="entry name" value="GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000740">
        <property type="entry name" value="GrpE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013805">
        <property type="entry name" value="GrpE_coiled_coil"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009012">
        <property type="entry name" value="GrpE_head"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21237">
        <property type="entry name" value="PTHR21237"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01025">
        <property type="entry name" value="GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00773">
        <property type="entry name" value="GRPEPROTEIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51064">
        <property type="entry name" value="SSF51064"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58014">
        <property type="entry name" value="SSF58014"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01071">
        <property type="entry name" value="GRPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 8" id="KW-0346">Stress response</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="52"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV58466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="192" mass="20905" checksum="05F0B26F02F1AE46" modified="2019-10-16" version="1">MNNPESNEPDETTTDDVGFDASSEPNSNDDALEAVAGEIGGDNEGPSLEVQLAEANDQILKLHAELENVRKRIRREAEEQIRYASLPLIQGLLEVFDNLRRALEAAETSQSTSGLVEGVQMVAKQFEDTLGKFNCKPIPAKGETFDPHVHEAISQMPSEEFAAGTVMIEATQGFQLHDRVVRPSQVVVSTGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZE8</accession>
    <name>A0A518IZE8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Arsenate-mycothiol transferase ArsC2</fullName>
            <ecNumber evidence="2">2.8.4.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">arsC2</name>
        <name evidence="2" type="ORF">Mal33_44950</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.8.4.2" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102100">
        <property type="term" value="F:mycothiol-arsenate ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023485">
        <property type="entry name" value="Ptyr_pPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036196">
        <property type="entry name" value="Ptyr_pPase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01451">
        <property type="entry name" value="LMWPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00226">
        <property type="entry name" value="LMWPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52788">
        <property type="entry name" value="SSF52788"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="LMWPc" evidence="1">
        <location>
            <begin position="7"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="146" mass="16023" checksum="C068AA47B2942C20" modified="2019-10-16" version="1">MTTTAKKKILFLCTGNSCRSQMAEGWARHFHSDRLEVHSAGIEAHGLNPNAVAVMQEAGVDISNQSSKLVGTLAEVPLDLVITVCGHADENCPVFSSQTQTVHVGFDDPPKLARDAATPEEAMDHFRRVRDEIRDFARDRLLKLVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZG9</accession>
    <name>A0A518IZG9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_45040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="172" mass="17927" checksum="82BDB43F4AA56E89" modified="2019-10-16" version="1">MRMMNWICVAVLAVVVGCGEKPTAEGPDAAEVAAASALYVAEAEPEGAVGVGEARESVETDQAVTLVGRIGGSSKPFVEGLAAFTIVDPKVPYCADDEGCPTPWDYCCTQPQVKENIATVKVVDADGGPVAFDARKLLNVKELSTVVVQGTANRDDQGNLTVAANKVFVRAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZJ0</accession>
    <name>A0A518IZJ0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glycosyl hydrolase family 10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_45240</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044846">
        <property type="entry name" value="GH10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001000">
        <property type="entry name" value="GH10_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31490">
        <property type="entry name" value="PTHR31490"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00331">
        <property type="entry name" value="Glyco_hydro_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="1 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GH10" evidence="4">
        <location>
            <begin position="206"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV58501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="496" mass="55445" checksum="78FD589686256861" modified="2019-10-16" version="1">MGLFRFEVPESFRASVPHWEAAYISGIEGIPWFGRVTWKDDQLLIQRNIDESGKISIPWPIADSGPRVLQSCSLRQRDTPYFLPLELARGACSNIRGQADQWQRSGMRLPDAYQSRLTEGIDRFLDAAQSYPLSARTAELSDASLAALQQASDALVDTYAAQALAYRKNNERQLGTLAAAYIAPPGPMTPGLEQAYLDAFNTIAIRTNWTAVESDMGKLDFEQFDPLFDWSHQHGLRVCAGPLFDFQQKQLPHWIYLLEEDFDGLLDTVSRYVATAVQRYRGKVQLWHAVSGLNTAGPIKLDEEQVMRLAVAVIQEIRRHDNRTPILISVDQPWGEYLSKSSDGISPLHFVDALVRSNLGIAGIGLEMRMNYWPEGTLPRSILDVSQQIDRWAQLGLPLLAQISVPAIAESEANTPRNALPIALGPEGQSTAADQLAYASRLTRMLLAKQMVHGVFWESWDDRQAHSMPGAGLVDSHGKPRPLLNELASLRRQFLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZK4</accession>
    <name>A0A518IZK4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Catalase</fullName>
            <ecNumber evidence="11">1.11.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">katA</name>
        <name evidence="14" type="ORF">Mal33_45460</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>2 H2O2 = 2 H2O + O2</text>
            <dbReference type="Rhea" id="RHEA:20309"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="EC" id="1.11.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the catalase family.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.6" evidence="11"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004096">
        <property type="term" value="F:catalase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08156">
        <property type="entry name" value="catalase_clade_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018028">
        <property type="entry name" value="Catalase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040333">
        <property type="entry name" value="Catalase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024708">
        <property type="entry name" value="Catalase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024711">
        <property type="entry name" value="Catalase_clade1/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011614">
        <property type="entry name" value="Catalase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002226">
        <property type="entry name" value="Catalase_haem_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010582">
        <property type="entry name" value="Catalase_immune_responsive"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020835">
        <property type="entry name" value="Catalase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11465">
        <property type="entry name" value="PTHR11465"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00199">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06628">
        <property type="entry name" value="Catalase-rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038928">
        <property type="entry name" value="Catalase_clade1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00067">
        <property type="entry name" value="CATALASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01060">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56634">
        <property type="entry name" value="SSF56634"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00437">
        <property type="entry name" value="CATALASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00438">
        <property type="entry name" value="CATALASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51402">
        <property type="entry name" value="CATALASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10 11" id="KW-0349">Heme</keyword>
    <keyword evidence="8 11" id="KW-0376">Hydrogen peroxide</keyword>
    <keyword evidence="7 10 11" id="KW-0408">Iron</keyword>
    <keyword evidence="5 10 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 11 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3 11 14" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Catalase" evidence="13">
        <location>
            <begin position="10"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="374"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="57"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="129"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="10">
        <location>
            <position position="339"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR038928-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR038928-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM01060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="QDV58523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="484" mass="55051" checksum="E2CA2559C192DE1B" modified="2019-10-16" version="1">MKKHDSKPTTTDAGCPVASDEHSLTVGPNGPILLHDHYLIEQMANFNRERIPERQPHAKGSGAFGHFEVTHDVSAYTKAAVFQPGTKTDTLIRFSTVAGERGSPDTWRDPRGFSVKFYTSEGNYDMVGNNTPVFFLRDPMKFQHFIRSQKRRADNGLRDHDMQWDFWSLSPESAHQVTWLMGDRGIPKTWRNMNGYSSHTYMWVNASGERYWVKYHFKTDQGVDFLTQDEADRLAGADGDYHRRDLFDAIKRGEYPSWTLKMQIMPFEEAKTYRINPFDLTKVWPHDDYPLHEVGRLTLNRNPTDFHTEIEQAAFEPNNLVPGIGISPDKMLLGRMFAYADAHRHRLGVNYKQIPVNAPQCPVFSYSKDGQGRTQNVSDPVYAPNSKGGPAADCERYPEDATWAADGEFTRAAYTLRKDDDDFSQAGTLVREVMDDASRDRLVSNVVGHLKAGVTDPVLERAFTYWRNVDEEIGNRIANGVKGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZL4</accession>
    <name>A0A518IZL4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_45630</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="61" mass="6739" checksum="3501CA33759F9B89" modified="2019-10-16" version="1">MRVVGGIVAEKRPKPLQRFWRGAAHRGGKRVPWRVATTGASTYLLSPEKQVGFPPRSGLII</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZR8</accession>
    <name>A0A518IZR8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_46040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
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    <sequence length="315" mass="34312" checksum="A30AF6BC54AA6F22" modified="2019-10-16" version="1" precursor="true">MRPTSALLVPLLLFATAALAQHPQLPVGPNADLGGVRLMPAGDEWNRDVSKDPVDPRSDAIIARIGAQTRLHEDFGLTWKGAPGGIPYYVVSGGQPKVPVTFRYADESDPGPYPIPPDAPIEGGPQGAGDRHVIVLDKDNWRLYEMFHAFPIEGGKSWKAASGAIFDLKDPKPRPAGWTSADAAGLPILPGLARYDELCVTKKLTHALRFTVKKSRRAYVSPASHFASKENDPDLPPMGMRVRLKADFDTSKFSGPARVLLEGLKTYGMILADNGGDWFVSGAPDDRWVHDELTPIRQVRGSDFEVVKMGPMTTR</sequence>
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                <person name="Jeske O."/>
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</entry>
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</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
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                <person name="Galperin M.Y."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 4">Mal33</strain>
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        <property type="term" value="C:integral component of membrane"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028087">
        <property type="entry name" value="Tad_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
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        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="Tad"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="2">
        <location>
            <begin position="178"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="418" mass="45362" checksum="D30F283DD4B28C3D" modified="2019-10-16" version="1">MFSDRPQRSIRNRRKGSIVVLVAITLPVLFILAALAINASYMQLTRTELFIATDAATRAAGRTFSELQNVNDAKTAAQSTAAKNMVAGQALQLRTGDAANEIEFGMTSNDGTYSRFQFNKVSSSSLASGDVKANAVRVLGRRDTGSLGGSIHTLFPKFLTTDTFNPTQTSVAMQVDRDISLVLDRSGSMDYLTITWPSGKSPYYTTTMVAAVTAGYLYTRYGNFYYSSGVSSDEYEKWAWEEHYELGPYPQTPWNSLVAAVDGFLNVLDETHPEEHVSIASYSSNATLDLYLDDDYDEVRDTLDDLYPSGSTAIGKGMQKGIQALLHSSARPYAAKTMVVMTDGMHNSGIDPVTVATSLVATYNLTIHTVTFGSGADKARMQSVAAIGGGSHYHAEDGTALKEVFEEIANNLPVLLTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0K3</accession>
    <name>A0A518J0K3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_48950</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="87" mass="9450" checksum="BBAD5B052A31A48E" modified="2019-10-16" version="1">MQNGTPGTLEQPVSGAVRSQTIEDAYLLLSDNPHLCGGNHSITIHQALDGSLVIDGRVISYHLKQIVQETVRPLGATIVNRVDVPHW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0Z2</accession>
    <name>A0A518J0Z2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_50340</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="386" mass="43368" checksum="63DFFC6C2DCC4F0F" modified="2019-10-16" version="1">MTIDILVAPKHRFDEILQDIHNTSGEVVSQDAGLSIDDVVTITAIYRNAIDDRAAWWKIRREVNARFATHPDIQTRTLAAIPGNVIGEIAGFSSENIGAIAERWIAEDGATPGTSQNAMDSLASLVAACNIATTQSTEVLLRTNQPPNAFERAFSTLGGKELANYQKAFGKWDDTKRHEAHQKYNYYQKQGLANCLALVLRDLTRPKTKKVNLKADQRTIQRHIAKRVKAYRKNPCPILGSPGDPVKLITLTFDIEYEGYVDFDFDTRPDAISDIRWEERTEECLEIPHWNEGMQRFCYDGIPLNVTLHDGSKTKITSEAGEDVYERYIGDMLRDSLIDARESGLFDNLPLARECFMLVAGTHANYAWPDERGFCDAHSAHRHDGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J138</accession>
    <name>A0A518J138_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Choline-sulfatase</fullName>
            <ecNumber evidence="10">3.1.6.6</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">betC_8</name>
        <name evidence="10" type="ORF">Mal33_50810</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="PTM">
        <text evidence="7">The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sulfatase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.6.6" evidence="10"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047753">
        <property type="term" value="F:choline-sulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004423">
        <property type="term" value="F:iduronate-2-sulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16030">
        <property type="entry name" value="iduronate-2-sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032506">
        <property type="entry name" value="DUF4976"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035874">
        <property type="entry name" value="IDS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16347">
        <property type="entry name" value="DUF4976"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0106">Calcium</keyword>
    <keyword evidence="5 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Sulfatase" evidence="8">
        <location>
            <begin position="34"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase" evidence="8">
        <location>
            <begin position="497"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4976" evidence="9">
        <location>
            <begin position="846"/>
            <end position="936"/>
        </location>
    </feature>
    <feature type="modified residue" description="3-oxoalanine (Cys)" evidence="7">
        <location>
            <position position="544"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR600917-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF16347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV59056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="958" mass="106220" checksum="4783A0518153F9C6" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J161</accession>
    <name>A0A518J161_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_50930</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="SSF117281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021850655" evidence="2">
        <location>
            <begin position="25"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV59068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="555" mass="60995" checksum="660216086DB0CAD6" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1B9</accession>
    <name>A0A518J1B9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ECF RNA polymerase sigma factor SigE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">sigE_6</name>
        <name evidence="5" type="ORF">Mal33_51670</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="3">
        <location>
            <begin position="33"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="4">
        <location>
            <begin position="124"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV59139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="180" mass="20748" checksum="E4F59A902E76E6CF" modified="2019-10-16" version="1">MQHRNERSEDEPIDGETVNAGAAGDRAALRSIYEATSDRVFRLMVRMVGPQDADDLTQQTFVRAFTRLAQFSGQSRFETWLYRLATNEALQHLRREKHRRTKQLIVEPTMLATDHVEQDERIAMLRQALDQLDPELRAIFTLKEESGLSYQEIAQALGIPEGTVGSRLNRARRELRKLLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1Z7</accession>
    <name>A0A518J1Z7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CsbD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_53850</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0337 (CsbD) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008462">
        <property type="entry name" value="CsbD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026042">
        <property type="entry name" value="YjbJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036629">
        <property type="entry name" value="YjbJ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05532">
        <property type="entry name" value="CsbD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039008">
        <property type="entry name" value="YjbJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69047">
        <property type="entry name" value="SSF69047"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CsbD" evidence="2">
        <location>
            <begin position="4"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV59357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="67" mass="7829" checksum="661392A10C2AE956" modified="2019-10-16" version="1">MNWDQIQGKWKQVKGKAQQKWGDLTDDDLDRIEGRRDQLVGTVQERYGIAKDEAEKQVREFEGSCNC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J215</accession>
    <name>A0A518J215_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">7-carboxy-7-deazaguanine synthase</fullName>
            <shortName evidence="5">CDG synthase</shortName>
            <ecNumber evidence="5">4.3.99.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Queuosine biosynthesis protein QueE</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">queE</name>
        <name evidence="7" type="ORF">Mal33_54080</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>6-carboxy-5,6,7,8-tetrahydropterin + H(+) = 7-carboxy-7-deazaguanine + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:27974"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:61032"/>
            <dbReference type="ChEBI" id="CHEBI:61036"/>
            <dbReference type="EC" id="4.3.99.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </cofactor>
        <text evidence="5">Binds 1 S-adenosyl-L-methionine per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="5">Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Purine metabolism; 7-cyano-7-deazaguanine biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="4.3.99.3" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00391"/>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016840">
        <property type="term" value="F:carbon-nitrogen lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904047">
        <property type="term" value="F:S-adenosyl-L-methionine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008616">
        <property type="term" value="P:queuosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00917">
        <property type="entry name" value="QueE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024924">
        <property type="entry name" value="7-CO-7-deazaguanine_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000370">
        <property type="entry name" value="QueE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="3 5" id="KW-0408">Iron</keyword>
    <keyword evidence="4 5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0671">Queuosine biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="6">
        <location>
            <begin position="16"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="10"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="5">
        <location>
            <begin position="35"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="5">
        <location>
            <begin position="114"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="25"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="29"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="33"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="36"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV59380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="231" mass="26348" checksum="B28452BB93E4BE1A" modified="2019-10-16" version="1">MRIAELYASRQGEGLLTGTSSAFIRVSGCNLRCWFCDTPHASWNPEGAQQSIDSIVADVLRLEVSHVVLTGGEPMLFPEIVTLCQQLADRGLHTTIETAGTIYQDTACDLMSISPKLAGSRPRDGSLSEKWQQQHDRRRWAVDVVRRLMVETPDYQLKFVVDQPDEQLEVQQMVDQLQPDVDPAKVWIMPQSRSTAELDAHESWLRPWCDQQGFQYCDRMHLRWYGNVRGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J238</accession>
    <name>A0A518J238_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GTP-binding protein Der</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_54320</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
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    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
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    </dbReference>
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        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="domain" description="G" evidence="2">
        <location>
            <begin position="285"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV59397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="529" mass="58428" checksum="91469C387A35D3E6" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J274</accession>
    <name>A0A518J274_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_54720</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
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    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
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    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="48"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="181"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV59437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="492" mass="54608" checksum="51DD2410714D6F25" modified="2019-10-16" version="1">MKVAAEEPSSPQALLPQRPRRMLAPAAYSEAAFPSLRLARSSRLARRIGKVLLVVLVVATFVVAIAPWQQSIKGSGTVIAFAPFERQQTIQTPIKGRIVRLGDNIVENGFVRKGDLIVEVADIDPEYLGRLESQLDASQRQVAAAETLWRASERNRDAAMMVVSSIEAQVKAYELVKKQVVAAADADVESARNKIQAEQQQLAEQQAALAQVQADFDRQRMLYDEKIASQSKFQSAQRKLKEAQAKVEKSKAYVRAAQSELESKQSDRQAKEQKAQVDIDYATATLRKATADIAKSESEVAKAESDLTKSQKDLLDSETKVARQRRQEILAPFDGYLTRITANQNSQVLKEGGVICTIVPDTTDRAVQIWLDGNDAPLVEAGRHVRLQFEGWPAIQFSGWPAVAVGTFGGQVVSVDATDDGKGKFRILVQPEESGQQWPSDRFLRQGVRTNGWVLLERVPLWYEIWRNMNGFPPVVSTEEPKNSKPPKLPKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J2C3</accession>
    <name>A0A518J2C3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_55150</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="2"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="39"/>
            <end position="46"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV59480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="225" mass="24457" checksum="571CE231F50CD1AA" modified="2019-10-16" version="1">MLELVDVKKQFPQPGGGTLTVLDIPKLSIDAGEQVVLIGRSGGGKSTLLHTIAGITKADGGKVIVNGYDIARLSEAGRDRFRAGAIGYVFQTFNLLGGFTALENVRLGMTFGSGRHDIARARHLLERVGLADRMHYKPSQLSVGQQQRVAIARSLAGRPKLLLADEPTANIDPANQQTIIDLIRDTCREEQVALLLVTHSMQVAEQFDRIEKFEDLNRAMATASI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J2F1</accession>
    <name>A0A518J2F1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_55510</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="142"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="269" mass="30120" checksum="471701B5F700C0A6" modified="2019-10-16" version="1">MIKKTLVGGSLALLLSGLVFGTGMSSYMKTGFGYARDAVKDVVPVNVEIDRARQMIDDLQPEIAKNMKLIASEKIHVAKLQKQIDSKADMLASAERDIMRLTADLQSGDTRFVYAKRTYSADQVKDDLAGRFNRFKTQKATVDKLQQMLTAREKTLQAAKDRMDEMLSAKRQLEVEVENLQAQYAANQVAHAASSLNLDDSHLSRTRDLIDSIRTRIEVDEELLAVDNQYYGTIELTEESDEDILNQVSTYFNGDQPSAEDSVAMIQID</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ILV9</accession>
    <name>A0A518ILV9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Bacterial type II secretion system protein F domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Mal33_00200</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.81.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018076">
        <property type="entry name" value="T2SS_GspF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042094">
        <property type="entry name" value="T2SS_GspF_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00482">
        <property type="entry name" value="T2SSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="94"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="118"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="266"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="297"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="domain" description="T2SSF" evidence="7">
        <location>
            <begin position="159"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV54079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="322" mass="36074" checksum="4F378811C3A82326" modified="2019-10-16" version="1">MTHPQLQIIIFISSTLLILALESLIYELFYRYRQRVAQRLNDDLGLSEARVTDQVQLFRNVASVKETVSLRERWQQCLARLLEQSGTQITMPQLVYGSLGLACLMGVIMFVVSRILHWPIVGFVIAGWLAGGLVIPAFVWMRYQSRRGKIYRQLPYTLELINRSVRSGQTMPAAFQMVANEVEAPLGEEFAYCIDQQHMGLSIEVAARSLASRTEIVELQIFAVALTIHARTGGSLADLLDNLSDTVRRRLKLQMKVQALTAEGRLQATTLVLLPIVSLIGLAILNRPYVSTLFETPSLLALAAGAQCLGGVWIYYTTRISY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IM34</accession>
    <name>A0A518IM34_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_00870</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="214" mass="24347" checksum="D3FFC3FC8EC38612" modified="2019-10-16" version="1">MNDDTLSPPFAPPRWLKIAISIAVVVHLWAVVAEPIRFSTRGPGGPSPAASAFRAPVGRYVDFLYLSHGYAFFAPDPGPSHLVAASWIDAEGRPQTETFPDRNNQWPRLLYHRHFMLTEFLHNMHEPQSLPPDVPRDSVIFREWRSGRDRYEMIRDGFANHLQHVHGGSAVQIDRVEHRMPGIPEFIEERIDLQNERLYLTLPDGLPAFDGIAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMZ5</accession>
    <name>A0A518IMZ5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_04100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="60" mass="6751" checksum="1DE4053B325E6184" modified="2019-10-16" version="1">MNYRNAALMLMLAIPTLGCSTEQPTMTDATEIEAFEQQVVNEEMAYHQQMAEEAKAAKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IN52</accession>
    <name>A0A518IN52_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphotransferase enzyme family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_04670</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015897">
        <property type="entry name" value="CHK_kinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004119">
        <property type="entry name" value="EcKL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02958">
        <property type="entry name" value="EcKL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00587">
        <property type="entry name" value="CHK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CHK" evidence="1">
        <location>
            <begin position="109"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="324" mass="35882" checksum="2AA533021E0C8E02" modified="2019-10-16" version="1">MTGAQSVQLGEPIQSLWSGYGVIQRALLRGLQDDGSGEPTPVVIKHIDVSQARSNRRGWGGDASHLRKVRSYGVEQVFYEKYSGQCGPSCQVPGLVAAHQKANEAGWVIVLTDLDAQGFDRRKNDLDQHGLRACLTWLANFHATFLGSSASGLWPIGTYWHLDTRPDELTALPAGPLKSSAPEIDRRLNAARFQTLVHGDAKVANFCFSDRDSGRVAAVDFQYVGRGCGMKDVAYLVSSCLSADDAASQEAAFLNVYFDALRDAIAVRHIEIDVAELEREWRALYRFAWADFYRFLAGWSPDHWKLNAYSDRITQSVIQQLGNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IN58</accession>
    <name>A0A518IN58_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_04830</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="176" mass="18758" checksum="C4DF87C8C5F6192A" modified="2019-10-16" version="1">MQQPGTQVPGTPTPSQSHQSRTRRHAIARRPTDQTKTHAVAFATSKQHRPLDLGLASQATTYRRLRDSGSPQLTGSETCVAGYQITSPNVAFATVAKLRDRDARPDRQTGGDGEIFLSSKKMEQGRGLIFFETTTLGDSKAPDASASPVAAREIAAASTARPSVRTAVLRGDADAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IND8</accession>
    <name>A0A518IND8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Choline-sulfatase</fullName>
            <ecNumber evidence="11">3.1.6.6</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">betC_2</name>
        <name evidence="11" type="ORF">Mal33_05630</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="PTM">
        <text evidence="7">The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sulfatase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.6.6" evidence="11"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047753">
        <property type="term" value="F:choline-sulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004423">
        <property type="term" value="F:iduronate-2-sulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16030">
        <property type="entry name" value="iduronate-2-sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032506">
        <property type="entry name" value="DUF4976"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035874">
        <property type="entry name" value="IDS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16347">
        <property type="entry name" value="DUF4976"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0106">Calcium</keyword>
    <keyword evidence="5 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Sulfatase" evidence="9">
        <location>
            <begin position="56"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4976" evidence="10">
        <location>
            <begin position="436"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="180"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="modified residue" description="3-oxoalanine (Cys)" evidence="7">
        <location>
            <position position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR600917-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF16347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QDV54608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="509" mass="55866" checksum="7322568B95DBF7BC" modified="2019-10-16" version="1">MRWFGFCVVVNRVVVRMSLVRIGMAGVVICSVLCGGLVAADDVAGGQTESAKRPLNVLFIISDDLTLNALSCYGNEVCQTPNIDALARSGTRFTHAYCQGTYCGPSRASFMSGYYPHATGILGYISPRKAIGDRATWAQHFKNSGYCTSRVSKIFHMGVPGGIEKGDDGADDPISWTERFNSQGPEWRAPGKGETLENNPDGKKPAVGGNTFVVVQADGDDLVHSDGRTAEKACQLIHEHKDEPFFLGVGFVRPHVPFVAPASYHEPFPEAEMALPEKVAGDWDDIPKLGINYKTSKNMKMDVQRQRKAVAGYYASVAYMDAQVGKVMAALQEAGIADRTIVIFTSDHGYHLGEHDFWAKVSLHEESVLVPLIIRVPGKQPAVCESLTELIDLYPTVSSLCGLEVLARLQGIDVSGMLDDPELELRETAFSVNGKGFLIRSQRYAYIRYRENASGGEELFDMQTDPQQYTNLVDDPAYAATLEKMRAEFAKTMQRVRDNDLAVSPRSKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INF6</accession>
    <name>A0A518INF6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_05880</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011453">
        <property type="entry name" value="DUF1559"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07596">
        <property type="entry name" value="SBP_bac_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="343" mass="36776" checksum="C1C1FA90491FBC56" modified="2019-10-16" version="1">MESRRTVRSGFTLVELLVVIAIIGILVGLLLPAVQAAREAARRMQCGNNLKQLGLALHNYHDIYNKLPPARVRTANMGVDTWTSNNINWAARILAQIEQNAIYNQIDWETPDGQSNATNTPLRQNTLGAFLCPSDPGNGGFQWTDPSGNKVAGATPVTADGHINYVICIGPDANLRNSPASSLGWAVEGYRDWNGNARGNGINGLRDFLDGTSNTLMVSEIIVGHPNIRANSTLTATTATQDDNGCTGSLNTATNSTSASGSSWFRGYEPNDMVFSTLMTPNSKLWDCGANSGNAMMAARSVHPGGVQTTLGDASVRFVGETIDWNTWKWLGGIRDGQVVSLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INZ2</accession>
    <name>A0A518INZ2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Periplasmic zinc-binding protein TroA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">troA</name>
        <name evidence="4" type="ORF">Mal33_07780</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the bacterial solute-binding protein 9 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007155">
        <property type="term" value="P:cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030001">
        <property type="term" value="P:metal ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006129">
        <property type="entry name" value="AdhesinB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006128">
        <property type="entry name" value="Lipoprotein_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006127">
        <property type="entry name" value="ZnuA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01297">
        <property type="entry name" value="ZnuA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00691">
        <property type="entry name" value="ADHESINB"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00690">
        <property type="entry name" value="ADHESNFAMILY"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1 3" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV54813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="327" mass="35841" checksum="9A7101DCCED319ED" modified="2019-10-16" version="1">MKIDRAVGSWMLLIALIVGCQRSPESATQTQRDPSRPIRVLTTTGMVADLARNVGDDQVEVVQLLGPGTDPHLYKPTRDDVQSILGADVVFYSGLMLEGKMGDTLVRAGRSKPVWAVTEAIDESYLLEPEDAQGHFDPHVWNDIQAWSQCIEVVRKALADFDPDHADDYQANAAKYQQQLNELHAYGLRSMQTIPAENRILVTSHDAFNYFGRAYDLQVLGVQGLSTESEAGLQRINGLVDLLIDKKVRAVFVESSVPRKNIEALVNGAASRGQEVKIGGELFSDAMGTAGSYEGTYVGMMDHNITRVVRALGGEAPERGLNDKLSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP07</accession>
    <name>A0A518IP07_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Toluene efflux pump periplasmic linker protein TtgD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ttgD</name>
        <name evidence="4" type="ORF">Mal33_07920</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039562">
        <property type="entry name" value="MFP_biotin_lipoyl_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13533">
        <property type="entry name" value="Biotin_lipoyl_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Biotin_lipoyl_2" evidence="3">
        <location>
            <begin position="64"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="104"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV54827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="387" mass="42055" checksum="0F560DCAC7D03CC3" modified="2019-10-16" version="1">MLHSYSYPALGVALVCCLAVGCGDSASQPSASERPVQKVTVMAAEETSVTDYVELVGRLAADKSVNIQSRVSGFLRSTHFEDGQRVKEGDLLFTIEPDEYDAIYNQALAQIDVAQAKLDVAEKTFGRSKELLANNAVSREEYDQDQATVAEAQAQLKAANADAARVKLDVGYTKITSPITGRVDRALLDDGNYVTGGFVGGTHLTTVVSDQPIKAVVNIDENVRLRVMRRQREMGGDGFKEANTLADLKIPCYLQLQDENDFPHEGVLDYAEIKIDQQTGTSQLRGLFPNKDGLLKPGMFVRVKIPVSDPHDAILIHDTAVGTDQATNFVYVVNSENKVEHRTVTLGDRKGNQRVVLSGIKPNESVVVAGLQLIQPGMTVDPTPQAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP22</accession>
    <name>A0A518IP22_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ABC-2 family transporter protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_08040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="122"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="147"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="173"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="227"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="317"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="346"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="396"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="425"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="459"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="490"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="518"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="544"/>
            <end position="566"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="584" mass="61971" checksum="852976105D9B44D4" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP82</accession>
    <name>A0A518IP82_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Agmatine deiminase</fullName>
            <ecNumber evidence="2">3.5.3.12</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">aguA_1</name>
        <name evidence="2" type="ORF">Mal33_08660</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.5.3.12" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047632">
        <property type="term" value="F:agmatine deiminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004668">
        <property type="term" value="F:protein-arginine deiminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009446">
        <property type="term" value="P:putrescine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007466">
        <property type="entry name" value="Peptidyl-Arg-deiminase_porph"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31377">
        <property type="entry name" value="PTHR31377"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04371">
        <property type="entry name" value="PAD_porph"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="382" mass="42199" checksum="7619587192A74ACB" modified="2019-10-16" version="1">MQEINRRDFVSRPIGLAATLACSRFLEAAEDPMLSAMPNYRSTAVELISQSTPVEDGYYYPAEWQPHESTIMVLPAPQNWNGLGIPMAHVRSQWANVANKLSEYEPVLMVVRPEDRSVAQRLMSREIELLELPVNDGWSRDSGPMVLVNPQGERRVAGFTFNGWGGKFPPFADDALLKARLCEHLDLPMYPIDLVLEGGAVAVDGEGTLITTEQCLLNPNRNSKLDRVSVERLLNQSLGTTKVIWLGDGLTPDPVTDGHIDGLAAFVEPGVVLLHTTDDRQDPNYRICQDAKQRLQAATDAKGKALQVIEMPMHADLSHMNFYIANDCVLVPTSDKRRENRRALAILKEAFPDRDVVAINSSILGEGGGGIHCITQQVPKAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP98</accession>
    <name>A0A518IP98_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl transferase family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_08790</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027791">
        <property type="entry name" value="Galactosyl_T_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02709">
        <property type="entry name" value="Glyco_transf_7C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_transf_7C" evidence="2">
        <location>
            <begin position="160"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="737" mass="84557" checksum="F165378C94008029" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPI4</accession>
    <name>A0A518IPI4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">pknJ</name>
        <name evidence="6" type="ORF">Mal33_09660</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="322"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="5">
        <location>
            <begin position="9"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV54998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="347" mass="38085" checksum="05E01FBB82548073" modified="2019-10-16" version="1">MKEIRLEDLQLGTTIGVGTVGTICDATDPRDGSRYAVKILHPAVSRDPLIRARFEREMAILQRLSHRNIIEYYGGGEHDGQLFYVMELVDGGSVKELFHGGQCLTWQEVVSLTIQICSALQYAHNHGVIHRDIKPANIFLTSDGTVKLGDFGIARDLHNSDLTGAGMTVGTHAYMAPEQITGETTITGKVDLYALGCCLYEMLTGEKAFSGDNFMQLFEAHLHGTPPRVRDRIPGCPSAFDEIIAQLLEKDPEKRPFNARHVQGVMLQIAAEHNVEESILAGAKADLGQRADVGAETAIGIGQNRLRDRIRRSGQGMERPEASLSMMLAIVAFVTLIIGVLLYFQAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPL6</accession>
    <name>A0A518IPL6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_10130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021832348" evidence="1">
        <location>
            <begin position="24"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="337" mass="36321" checksum="6F64DD0ED02D4F9E" modified="2019-10-16" version="1" precursor="true">MIRRIPSLACLIAVLMLVHVARSDDAPPAPPHVLVVVGAGGSEEYQTAFATWADRWKSAAGLLDGASYHEIGREEGQSDSSDKDRLNERLAELSDLKAEAVWIVLIGHGTFDGKSAKFNLRGPDVSAEELSGWIEPMRSPLIVVNCASASGPFINRLSAVGRTIVTATKSGQEQNFARFGDYLSQAISNIAADLDHDDEVSLLEAFLSASDQVAKFYEAENRIATEHALIDDSGDRLGTPATMFQGTTAVAVPQPKAARDGGVAARRVIFQSPKAVVLTPAQRESRAAIEAEIDRLKLRKSELATDQYFAQLEPLMLQLAELYAAAEAEDSDESQGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPV7</accession>
    <name>A0A518IPV7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Type II secretion system protein E</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">gspE</name>
        <name evidence="3" type="ORF">Mal33_10980</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GSP E family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001482">
        <property type="entry name" value="T2SS/T4SS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00437">
        <property type="entry name" value="T2SSE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T2SP_E" evidence="2">
        <location>
            <begin position="51"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="447" mass="49537" checksum="B5A8501ED4F79E06" modified="2019-10-16" version="1">MAKQQEEPQLWQTVAPCEFKGIHEDSGLAQGLLISARQSPGFPVLAGQLGHAFANRATHLMLDYNAQMVNMRYQIDGMWEQLPPLPRDAGDAMLVAAKTLCRMNPADRKNAQQGKTLAIMGRDKYNVKIQSQGVPTGERVMLTLDKKDIPFKTLDDLGMRDKMQVQLKEALNDKGHMVVISAPKGGGLTTSWTIALEAADKFVSDFQAIEPKGSDEPDIINVSPNYFGPDAKNDTARDAVRALSLREPDVFVMPELYDEETIKLLHAQTKIEKQVISRIVASDAVEACARLVHKYRGAAKEIVDMLSHVTNVRLARRLCETCRQGFTPPPQLLQKLGIPQGRVAMMYQPFVPPPIEQQVDEKGNPAPLPPCPKCANRGYYGRFGIYELLTVGPKLKDALLKTSDVNKLRQVAKAEGHRNLQDEGIMAVARGTTSLEEMRRIFSSGNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPY4</accession>
    <name>A0A518IPY4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HSDR_N_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_11170</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029464">
        <property type="entry name" value="HSDR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017035">
        <property type="entry name" value="UCP035009_HsdR_All3000-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13588">
        <property type="entry name" value="HSDR_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF035009">
        <property type="entry name" value="UCP035009_HSDR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HSDR_N_2" evidence="2">
        <location>
            <begin position="24"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="355"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="374" mass="42042" checksum="C55884052FA6A581" modified="2019-10-16" version="1">MELFDTLTRLASRLESQRELLETEEATKNAVIMPIINALGYNVFDPSEVIPEFTADVGVKKGEKVDYAIVVGGDPTILIECKPITTKLDFKHASQLYRYFGVTSARFAVLTNGQYLWFYTDLDSPNKMDTKAFFKFDLNDFDARDVAELQKFSKTVFNLENILANATELKFTQQLSGILAAELDSPSDELVKHLTSKIYEGRFTSAVCDQFRPLVKTAFRDFINDRLSNRLKSALQGVDADSALPSDSGDELKPDDGIVTTAEEMEGFHIVRAMLAKQIPIKRVVMRDTKSYCGVLLDDNNRKPICRLHFNGSQKYLGTFDADKNETRNAIDRIEAIYEFEEQILATVLRHDGTKETASASEPELSSHALDDSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQ11</accession>
    <name>A0A518IQ11_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_11290</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="162" mass="18665" checksum="EED6758526A6DE0A" modified="2019-10-16" version="1">MPERKSVTAAELMAELEADPEWVARREAKERESEEHRKVCAADQLGLVREIRDAGYDVDSVWDLVNNSPHPVLERRFLGEYPDAYPILVQHLSVPHRKEIREGLIRALTVKDGGPEVESTLLECFYAETDEKMRWVIANALRTAMPYHRRKKHPEIKAALNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQ16</accession>
    <name>A0A518IQ16_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Aliphatic sulfonates transport permease protein SsuC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ssuC</name>
        <name evidence="6" type="ORF">Mal33_11590</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="65"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="96"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="127"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="227"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="61"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV55189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="258" mass="27987" checksum="FA8EDA5DAF5A6115" modified="2019-10-16" version="1">MNQRAERFTDSLWPMLAALVLLIAGWSAAKYLYAVEDYFVPYPWTVVTAAVRIAPELAAATWLTARAAVCGFVLSTLAGSVIAIVFAQFRLLRLGCFPYAVILQTVPIVAIAPLITYTRGPGFESVVLIAFIVSLFPIIANTTAGLTSVPSGLQELFRLNHATRWQQIWKLQIPHAVPNLITGMRTSAGLAVIGAIVGEFFAGNSSRGHGLGFMVPQKMDRLRADEAFAAVAMATLLGIAMFAAVSFLRSTVLRRWSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQ57</accession>
    <name>A0A518IQ57_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Doubled CXXCH motif (Paired_CXXCH_1)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_11950</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036280">
        <property type="entry name" value="Multihaem_cyt_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48695">
        <property type="entry name" value="SSF48695"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="98"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="543"/>
            <end position="600"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="783" mass="84431" checksum="AEC9018AA0CA3F64" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQC4</accession>
    <name>A0A518IQC4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Farnesyl diphosphate synthase</fullName>
            <ecNumber evidence="3">2.5.1.10</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_12570</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the FPP/GGPP synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.10" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004337">
        <property type="term" value="F:geranyltranstransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00685">
        <property type="entry name" value="Trans_IPPS_HT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000092">
        <property type="entry name" value="Polyprenyl_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033749">
        <property type="entry name" value="Polyprenyl_synt_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00348">
        <property type="entry name" value="polyprenyl_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="SSF48576"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00723">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00444">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="299" mass="31946" checksum="287FEEB48B6A63EA" modified="2019-10-16" version="1">MSNPASPVKNPLADLVPEIDAALNAALAPQEGCPPELNEAMRYSLMSPGKRLRPALVLMAAEACGGERSEAIAAAVAIEMVHAYSLIHDDLPAMDDDDLRRGRPTCHKQFDEATAILAGDALLTAAFETLATGIPQPERAVRACEVLAKSAGRSGMVGGQTDDLLAENRNERHNLAWLEAIHRRKTGALFTCSLQLGAISVGAQESQIASLTDYARDLGLAFQIVDDLLDWEGDGDEMGKQSGKDAARGKLTFPGFIGVDASRSKASELVTAAKQHAELFRGTGQRLSQLADYVLQRSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQF2</accession>
    <name>A0A518IQF2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_13000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025990">
        <property type="entry name" value="Cys_rich_CPXCG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017143">
        <property type="entry name" value="UCP037225"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14255">
        <property type="entry name" value="Cys_rich_CPXG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037225">
        <property type="entry name" value="UCP037225"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="60" mass="6604" checksum="CE2608A6424DC8B6" modified="2019-10-16" version="1">MQDEATYICDGCGEEIVIPIDLSAGVSQDYVEDCPVCCRPNVIHVDIDADGMANVWTERE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQG2</accession>
    <name>A0A518IQG2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Flagellar basal body P-ring biosynthesis protein FlgA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_12930</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Periplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044780">
        <property type="term" value="P:bacterial-type flagellum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036732">
        <property type="entry name" value="AFP_Neu5c_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017585">
        <property type="entry name" value="Flag_basal_body_FlgA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039246">
        <property type="entry name" value="Flagellar_FlgA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013974">
        <property type="entry name" value="SAF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36307">
        <property type="entry name" value="PTHR36307"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13144">
        <property type="entry name" value="ChapFlgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00858">
        <property type="entry name" value="SAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51269">
        <property type="entry name" value="SSF51269"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03170">
        <property type="entry name" value="flgA_cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0966">Cell projection</keyword>
    <keyword evidence="5" id="KW-0969">Cilium</keyword>
    <keyword evidence="5" id="KW-0282">Flagellum</keyword>
    <keyword evidence="3" id="KW-0574">Periplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="SAF" evidence="4">
        <location>
            <begin position="232"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV55322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="364" mass="40271" checksum="D7C9786F5EB4C693" modified="2019-10-16" version="1">MIAERHGFRGSATQRRSVAGWQLVCAVGVWLGLFSSATLAQQSDPWTLQLKPNVTVTSSIVRVEDVVQPVSIPDNVWDQLRKSTVGLIPTDGRPLQLMRYRLAEALNHSKLVTAPILWVGPESTSVRSNPVVQVAAKVVTTVAEVAPKEIDPQSKRLIERVVEKAMQDYETDFEYKIDWERLPIAQVEEITSYQRVAVPTTITAGVARFVLTSTVEGEKREVPVYLQINELPRGIVATQNLSRGQIIGPSQLQWKVIDSTVRSDHLATDMSQLIGQEVKRNVPAGRWVQQTDVGPPILVRRNDMVEVMVVGGAIVIRTGGKAMGEGSEGDLIQIETIEDRKRLLARVISTGLVEIVTRAPQVQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQH2</accession>
    <name>A0A518IQH2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_13160</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="112"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="166"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="75"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV55345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="186" mass="20270" checksum="3A5BFE0965955AF2" modified="2019-10-16" version="1">MGKASMFIIVAILALGAIGCRNDENKRLAEMAERNIERQAQQEVRNTALQHQVAEGTKRLVEADAAARKTIAEIHRDVQTERQTLGAQRDQLENERRQIAAARNRAPIVAEAITAIGLLAACLVPLLIALQILRRSDSPDESGTVAELLLNDIVAEQPAIVRIVDAGPKESPSEVAGRIADHRHVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQJ1</accession>
    <name>A0A518IQJ1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_13280</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="47" mass="5602" checksum="DFA30FF1BEB8E7C2" modified="2019-10-16" version="1">MEGLAGWIIIGVVAWWFYKTGKRTGSRKGYNVGRSRSRSRRDHHRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQM2</accession>
    <name>A0A518IQM2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cobalt-zinc-cadmium resistance protein CzcC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">czcC_1</name>
        <name evidence="2" type="ORF">Mal33_13490</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="565" mass="61128" checksum="4114D62203CD4098" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQS3</accession>
    <name>A0A518IQS3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Mal33_14080</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the glycosyltransferase 87 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016758">
        <property type="term" value="F:hexosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018584">
        <property type="entry name" value="GT87"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09594">
        <property type="entry name" value="GT87"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="122"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="147"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="176"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="199"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="226"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="290"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="331"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV55435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="422" mass="45029" checksum="BD6D7F6FC08B4B4C" modified="2019-10-16" version="1">MTAPTQPAANRAPSTGRAVGAATLLAIVVVCLIAATANNFRCETEPRKSALGGDFLQEWIGGRLVARGDAELLYDPATTDQMQHDAALVGFEWPESEYYPMVYPPAWYAAISPLSRIEYTSACYVWLALLATSLPLLAWLMSRGLQLQAGQVVAIVIGLVLFPPAMQSLVMGQKSLLWLGVWVGVFALCRSGREGWAGTLFGFMLMKPILVPVMIGMMIARRRWSFVFAAAGSAATIAAASLLFVPVSSWIDYVGVVAGVGTYHQTAGYSADLAQNLGALLLTATGPHRAVYWGLFAAGAAIVIVLMGRAARIGEPQTDSPQNVPALDDRFWIATVLGTILLSPHYFAYDLTLLGLLPIAIACQGRLGEAMPWIVACFVATAINDSIVQTLGFPPTPVVLLAMLAWYGRPPMTLVAGCPAGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQW8</accession>
    <name>A0A518IQW8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_14560</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="89" mass="10202" checksum="4575DE1984BE41B4" modified="2019-10-16" version="1">MRATQEQTPAQAFEHHLDQETAFEAVSFADRGLQVKEIAQLLARSEPVVREALEGQQRPLWIPTPDEIVTRAAEIRAGWSEDEKHARRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQY0</accession>
    <name>A0A518IQY0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ubiquinone biosynthesis O-methyltransferase</fullName>
            <ecNumber evidence="3">2.1.1.222</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ubiG_1</name>
        <name evidence="3" type="ORF">Mal33_14830</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.1.1.222" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="Methyltransf_25" evidence="2">
        <location>
            <begin position="63"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="236" mass="26280" checksum="4CCBE5DBFFD21CB6" modified="2019-10-16" version="1">MVTRWLKERRREPEWMDQPDLDPALHHQALAGLTRVNAISGTTATLWRPIEKLAQQTQKPTRVLDVASGGGDVAIGLAQQAVKSGLPVSVDGCDMSPVALKYAQARADGQDLKVNFFKADVLADPFPSGYDVICCSLFLHHFDPPQVIQLLTAMRESGARLIVISDLLRTRLGYVMCWAGIRMLTRSRMCHVDGPLSVQGAFTRSELEELADRAGLQSMAFQNVWPQRLLMTWERP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IR96</accession>
    <name>A0A518IR96_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose 3-N-acetyltransferase</fullName>
            <ecNumber evidence="3">2.3.1.197</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">fdtC</name>
        <name evidence="3" type="ORF">Mal33_15920</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.3.1.197" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018357">
        <property type="entry name" value="Hexapep_transf_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14602">
        <property type="entry name" value="Hexapep_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00101">
        <property type="entry name" value="HEXAPEP_TRANSFERASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="192" mass="20476" checksum="60FD4D1C7623FB23" modified="2019-10-16" version="1">MHHATAIVETDTIGPETNVWAYAHVMPGAIVGNRVNIGDHAFVEGGAVIGDNVTLKNSVCVWEGITIEDDCFIGPAVTFTNDRNPRSPRMDAAAQRYAERDNWLAKTVVRRGCSIGAASTICPGLDLGTFSMIAAGSVVTRDVPAFALVMGSPARRVADVCSCGQRLPGKFDDCDCEACSETATQRVQRGFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRC2</accession>
    <name>A0A518IRC2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Coproporphyrinogen III oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Mal33_16100</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039661">
        <property type="entry name" value="ELP3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032432">
        <property type="entry name" value="Radical_SAM_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023404">
        <property type="entry name" value="rSAM_horseshoe"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005911">
        <property type="entry name" value="YhcC-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11135">
        <property type="entry name" value="PTHR11135"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11135:SF1">
        <property type="entry name" value="PTHR11135:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16199">
        <property type="entry name" value="Radical_SAM_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01091">
        <property type="entry name" value="uncharacterized_CHP01210-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01212">
        <property type="entry name" value="TIGR01212"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="7">
        <location>
            <begin position="31"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV55632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="327" mass="36965" checksum="49495C55B08DD594" modified="2019-10-16" version="1">MQSSIPPGHEHFDWRLDGAFYYPYSAYLRNRFGGRVQRVSINAGFTCPNADGTLAKGGCNFCNNPSFSPSRRTRRYEIREQIDRGIEALKRRYSNIKGFIAYFQPATNTYADVDHLRALYEESLSHPEVVGLAIGTRPDCVAEDVLDLISELAQQRYVSVEYGMQTIHAESLDWMNRAHYHDSMIDAVERSRGRGFEISGHVILGIPRESHADMMETAVEVARLNLDAVKIHNLYAVKNTRLGDEVAAGEVELMPRDEYVQTVVDFIERLPETMIIERVSGEAPPAYLIAPEWCLQKSSLRHAIEQEFKQRGSRQGSRYVAAASSDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRI6</accession>
    <name>A0A518IRI6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major Facilitator Superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Mal33_16780</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <sequence length="531" mass="55351" checksum="9514A3248A90DC92" modified="2019-10-16" version="1"> </sequence>
</entry>
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            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
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                <person name="Rast P."/>
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                <person name="Storesund J.E."/>
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        </source>
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        </source>
    </evidence>
    <sequence length="610" mass="67914" checksum="B3AE10FA1B6542B1" modified="2019-10-16" version="1"> </sequence>
</entry>
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                <person name="Pinto D."/>
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                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
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                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
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                <person name="Mueller R.-W."/>
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                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
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            <strain evidence="1 2">Mal33</strain>
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            <dbReference type="EMBL" id="QDV55786.1"/>
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    </evidence>
    <sequence length="310" mass="33500" checksum="8CD474F410E8F7A0" modified="2019-10-16" version="1">MSDSESLPKFFDLQVNGFFGADFNDASLSESQLDAAVTRLQQDNVSGILATVITDSNEAMLARVRRIVELRKLLPAAAAMIPGLHIEGPFISPVTGYIGAHPAAHARQCEQGFMEELLAAGEGLIRLVTIAPEQDPGGKLTRWLVDQNVVVAAGHCDPSVEQLATTIDQGLSMFTHLGNGCPQLMHRHDNIIQRVLSMSDRLVVCMIADGFHVPLVALQNYIRCIPPENLVFTTDCIAAAGLGAGVYTLAGQQIRVEAGMPPTSADGSHFVGSSAQMPDMYRRLRDELGISQKQLEYSMFELPRRATGCA</sequence>
</entry>
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    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Boedeker C."/>
                <person name="Pinto D."/>
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                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
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                <person name="Lage O.M."/>
                <person name="Pohl T."/>
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                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
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    </feature>
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        </location>
    </feature>
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    </evidence>
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    </evidence>
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        <source>
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        </source>
    </evidence>
    <sequence length="226" mass="24333" checksum="41D585DCEB09D8BB" modified="2019-10-16" version="1">MVAFRSAKGRGPGNALSRSERRPYEHEAQASDSTRRIERSVGLGSRDSLNPRLQITRLRFVLVLQSSALARVCVIAGCSFVRALPMVAFRSAKVRGPGNALSRSERRPYEHEAQASDSTPANRASDSTRQIERVVPPPANQASDSTRQIGLMIPHANRAIGYSGSMPKSRIVSSVSNFNPRSANLASPPARRSMIPRTPSTFKPKASAASTACNALPPLVITSSTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
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    <name>A0A518ISR8_9BACT</name>
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    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
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                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
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    <evidence type="ECO:0000313" key="4">
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    <sequence length="612" mass="67496" checksum="A833FBEEFC1673C9" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
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                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
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                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
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                <person name="Devos D.P."/>
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                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="6 7">Mal33</strain>
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            <topology evidence="1">Multi-pass membrane protein</topology>
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        <property type="entry name" value="AA_permease_2"/>
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        <source>
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</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISW8</accession>
    <name>A0A518ISW8_9BACT</name>
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        <submittedName>
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        </submittedName>
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    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Pinto D."/>
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                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
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                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
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                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
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                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">Mal33</strain>
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        <location>
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    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
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            <dbReference type="EMBL" id="QDV56187.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="153" mass="17513" checksum="88D99F9B8E1647EC" modified="2019-10-16" version="1">MAGKSADEWFAEYELSHRNPVNKRIHWICVPVIAAAFLGLLWELPAPRQSWITINWSIVAMLAALAFYIRMSLRLAIGMAIAFALLACGFIAYRQTLATPLWIPSLTLFVTAWIGQFIGHQIEGKKPAFFQDLQFLLIGPAWVLRDFYRRMGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IT03</accession>
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        <submittedName>
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    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
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                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
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                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="1 2">Mal33</strain>
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    </reference>
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    </dbReference>
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            <dbReference type="EMBL" id="QDV56211.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="648" mass="70508" checksum="8B5B14F2A01FCAD4" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IT41</accession>
    <name>A0A518IT41_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Site-specific DNA-methyltransferase (adenine-specific)</fullName>
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    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2'-deoxyadenosine in DNA + S-adenosyl-L-methionine = an N(6)-methyl-2'-deoxyadenosine in DNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:15197"/>
            <dbReference type="Rhea" id="RHEA-COMP:12418"/>
            <dbReference type="Rhea" id="RHEA-COMP:12419"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90615"/>
            <dbReference type="ChEBI" id="CHEBI:90616"/>
            <dbReference type="EC" id="2.1.1.72"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.1.1.72" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="REBASE" id="355346">
        <property type="entry name" value="M.PbaMal33ORF22380P"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008170">
        <property type="term" value="F:N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009007">
        <property type="term" value="F:site-specific DNA-methyltransferase (adenine-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022749">
        <property type="entry name" value="D12N6_MeTrfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003356">
        <property type="entry name" value="DNA_methylase_A-5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038333">
        <property type="entry name" value="T1MK-like_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12161">
        <property type="entry name" value="HsdM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02384">
        <property type="entry name" value="N6_Mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HsdM_N" evidence="6">
        <location>
            <begin position="30"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="N6_Mtase" evidence="5">
        <location>
            <begin position="181"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="725"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="752"/>
            <end position="779"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV56256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="869" mass="98104" checksum="243C38C23DFD8795" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITA6</accession>
    <name>A0A518ITA6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Acetylglutamate kinase</fullName>
            <ecNumber evidence="7">2.7.2.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">N-acetyl-L-glutamate 5-phosphotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">NAG kinase</fullName>
            <shortName evidence="7">NAGK</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">argB</name>
        <name evidence="9" type="ORF">Mal33_23080</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + N-acetyl-L-glutamate = ADP + N-acetyl-L-glutamyl 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:14629"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:44337"/>
            <dbReference type="ChEBI" id="CHEBI:57936"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 2/4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the acetylglutamate kinase family. ArgB subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.8" evidence="7"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00107"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003991">
        <property type="term" value="F:acetylglutamate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042450">
        <property type="term" value="P:arginine biosynthetic process via ornithine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04250">
        <property type="entry name" value="AAK_NAGK-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00082">
        <property type="entry name" value="ArgB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004662">
        <property type="entry name" value="AcgluKinase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037528">
        <property type="entry name" value="ArgB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001057">
        <property type="entry name" value="Glu/AcGlu_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041727">
        <property type="entry name" value="NAGK-C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000728">
        <property type="entry name" value="NAGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00474">
        <property type="entry name" value="GLU5KINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="SSF53633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00761">
        <property type="entry name" value="argB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="1 7" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AA_kinase" evidence="8">
        <location>
            <begin position="24"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="64"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="7">
        <location>
            <position position="29"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="7">
        <location>
            <position position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV56326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="293" mass="31540" checksum="B09BC2377A7AAAA3" modified="2019-10-16" version="1">MDQAIAKADTLIEAMGWIRQFRGKTTVIKLGGSLLDDTEALHHILLDVIFMETVGMRPVIVHGGGKAINRALAAEGIEPVFIKGRRVTDPATLQIVRKVLAGETNTMITQEVERMGGRAMNLSFDTTCVLRGKKLQLEGEADLGAVGYVTDVDRHVIESLSYTNQVPVIPSMCEGPDGNPLNVNADTAAMAVAQALGAEKLIFLSDVNGVRMDKDDPSTTIRSLTSDEAKDLIASGVIEAGMIPKVEACLETLDRGVGKVHIVDGKLRHSLLLEIYTTSGIGTEIVKQRMPVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITC8</accession>
    <name>A0A518ITC8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_23280</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009599">
        <property type="entry name" value="DUF1207"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06727">
        <property type="entry name" value="DUF1207"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="343" mass="37989" checksum="EE472317B0033C32" modified="2019-10-16" version="1">MQASCLYHSNFLNRLVAVAGSLAWILVLLTAPQSIVTGDDRIAAVSWSEVAALAADPVVTVDEPAVIFDPAAQPIPPLPPAMITAAAPQDAWTWQTLPEGLLWHSYMAGPHEPRISTVLFSEHDGGAFWDATLGGRVGLLRYGSSDAKHPEGWQWDLEGAVITRLDLYNSEDVESNDFRFGTELTKALGAWSLKFGYFHISSHVGDEYMERNPTFERINYVTESLVLGASYQAYESLRLYGETAFAFKMSGGARPWQFQTGFEFVPAPKSLKWGGPFSAMNLDIREAVGYSPSLTAQMGWQIPGSQSGRRLRWGAQYTNGHSSQFEFFQRKEQTIGGGIWFDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITI7</accession>
    <name>A0A518ITI7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA helicase</fullName>
            <ecNumber evidence="3">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">dnaB</name>
        <name evidence="11" type="ORF">Mal33_23800</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the helicase family. DnaB subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036185">
        <property type="entry name" value="DNA_heli_DnaB-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007694">
        <property type="entry name" value="DNA_helicase_DnaB-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007693">
        <property type="entry name" value="DNA_helicase_DnaB-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016136">
        <property type="entry name" value="DNA_helicase_N/primase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00772">
        <property type="entry name" value="DnaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03796">
        <property type="entry name" value="DnaB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48024">
        <property type="entry name" value="SSF48024"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51199">
        <property type="entry name" value="SF4_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0235">DNA replication</keyword>
    <keyword evidence="9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7 11" id="KW-0347">Helicase</keyword>
    <keyword evidence="6 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SF4 helicase" evidence="10">
        <location>
            <begin position="172"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QDV56390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="467" mass="51390" checksum="0F51F9FF83BC5303" modified="2019-10-16" version="1">MTDEANPPADEAAVLAGMILDPKQIDAVVGHLSAADFQHNHLRELFGFLIDANAAGRPTDSRSVLMQLRESGALKRIGASFIGRLTNAIGSAANVPYHVAKVRHAAILRRIRQVVPTIEAIADDDTQTPTQILDRIDAELIQIRQYDQPPAAVSHLGDDALRLCDEIDAAAGTGETRGLRTGLECFDQINGGFQDGTLNIIAARPSNGKSVLGLQWAQSIGTGFDYSVSDEGNYFVAQQPPKSTLFISLEMTRAELSARALASTTRIDGRRINSYRTTADQRRRLRAAAESMKATQTRLWQPHRATVSSIRATARLHQRQHGLGCLVVDYMQLVDSERGAKHDKETYRIGEICRGFKSLAMELGIPVVVLAQLNRESEGSLPTLAQLADSGKIEQHADTITAIHRQRGETNDANLVLLKWRNGKTPTIDITFDRQHSRFVGIEPKPVQPFTNLPNDTLDYDTLVRRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITP5</accession>
    <name>A0A518ITP5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF262 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_24520</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004919">
        <property type="entry name" value="DUF262"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03235">
        <property type="entry name" value="DUF262"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF262" evidence="1">
        <location>
            <begin position="7"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="530" mass="60137" checksum="3E4D03F756CD73F2" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITQ3</accession>
    <name>A0A518ITQ3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_24550</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="46" mass="5137" checksum="563955F87C3778C7" modified="2019-10-16" version="1">MRQADRQQFADLLTLLVGKTPIQATFLAPHAPELEHPVGGRFTYSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITR8</accession>
    <name>A0A518ITR8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_24680</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetia</taxon>
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            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="84" mass="9781" checksum="63D4E924C1D584E9" modified="2019-10-16" version="1">MNESLSSRVAFFRLRITRIVMPWRRVDRLASRVAVLESNVVYLANENQRLLGHMTFYAIQLKELGERLNDQTAKQSPSFEPSNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITY2</accession>
    <name>A0A518ITY2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Porin B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">oprB</name>
        <name evidence="4" type="ORF">Mal33_25370</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
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            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the OprB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015288">
        <property type="term" value="F:porin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008643">
        <property type="term" value="P:carbohydrate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007049">
        <property type="entry name" value="Carb-sel_porin_OprB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038673">
        <property type="entry name" value="OprB_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04966">
        <property type="entry name" value="OprB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU363072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV56545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="452" mass="49655" checksum="A20462037BD9A252" modified="2019-10-16" version="1">MGNKREPIDKQGVKRTRTNSRQIPNPLQQMMHSLAKSHAAIVIASVIAVAGILSVRADERSVDCDVETWCCDDPTQEAICAREYLLGDWCGIRPCLQDSGITPFLYYDSITAANVDGGIKADQDFTGQVYAGADLDLETLLGWNRTTLKISTVQRHGDSISPSVGGIYDPMCIFGGQVLFLYQLWLEREVCDNWSIKAGRVSADTDFLNDGLYRYSLSTAINGPIRATLLESTVTSFPFPVWGGRVKYTPDDKHQFQVGAYQIGDDMFDFTKHGLDFSIRSDDGVSILMQYDWTSTVCERPTHLFVGAVNSFFEFDNHDGVGTTDYVLRVYAHLAVEVVPNLTVFGFAANSEQDEVALTPLQVSFGINGKGMFSSRPDDHTMFFATCGDLSDDYGDSIGEAVDHAIVYEVGHRFQVLPSAYIQPALQYIVTPGGTGDIANSTVLGAWVGATF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IU14</accession>
    <name>A0A518IU14_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Subtilisin E</fullName>
            <ecNumber evidence="7">3.4.21.62</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">aprE</name>
        <name evidence="7" type="ORF">Mal33_25420</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the peptidase S8 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.62" evidence="7"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Peptidase_S8" evidence="6">
        <location>
            <begin position="90"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV56550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="864" mass="90925" checksum="2970763214E774BF" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IU55</accession>
    <name>A0A518IU55_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_26180</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="83" mass="9074" checksum="0CA0B8321257EE60" modified="2019-10-16" version="1">MSDLFATPTAQSVFSLLILSILIAIGVWLVARFRGGTDEDREPGSEVLSNFEEMLREGDISPAEFRTIEAVVGEKLNSEAKDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUU3</accession>
    <name>A0A518IUU3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ribose import ATP-binding protein RbsA</fullName>
            <ecNumber evidence="5">3.6.3.17</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rbsA_2</name>
        <name evidence="5" type="ORF">Mal33_28590</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.6.3.17" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="12"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="243"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="44"/>
            <end position="51"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV56858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="509" mass="55534" checksum="207C5B748C9A4550" modified="2019-10-16" version="1">MTSHSPAAVPLLEVRDVTKRFAGVAALSGVSLSATRGQVHAVIGENGAGKSTLMKILAGVQLPDSGQILLDGKPVRIDSVQRALELGIALIHQELNLSDNLDVGANLFLGREPRRFGMIDFGKIREASRQYLQMVGLDIDPGTIAGDLTIGMQQMVEIAKALSVDARLLIMDEPTSSLSQHETEALFRVIRRLREQGVTILYISHRLGEIIELADTVTVLRDGENAGHLSKDQISHDAMVQRMVGRDISKYYARAEHPRGDVMLEVKQLRTSTWPAHALNFKVHAGEIVGVAGLVGAGRTELMSTIFGTQRAVSGEVLVAGKPLRLRHCRDAIDAGIAMVPEDRKQQGLILEMGIRMNVGLPGLERHRHLGGFLNRQKERADSDRMIAEMKIKSSSDMLPTQFLSGGNQQKVVIGKWLSMHPKVLLLDEPTRGVDIGAKQEIYRLMEELAASGVAVLFVSSEMEEVLSMSDRTIVMHEGKISGELRREQLSEEAVMQLATGNPVAAAST</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUZ4</accession>
    <name>A0A518IUZ4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Quinone oxidoreductase 1</fullName>
            <ecNumber evidence="2">1.6.5.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">qorA_2</name>
        <name evidence="2" type="ORF">Mal33_29120</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.6.5.5" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003960">
        <property type="term" value="F:NADPH:quinone reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKS_ER" evidence="1">
        <location>
            <begin position="10"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="332" mass="35223" checksum="7DD01E49A7E4D793" modified="2019-10-16" version="1">MKAAFIKTTGDADVIQYGDLPDPQPGQGQVLVRTEAVSVNPIDTYVRSGMIAMDLPDPFIIGCDIAGTIAAVGEGVTGFRIGDRVWGSSQGLLGRQGTFAELCAIDQDWLYELPDGVAAEDAAACALVGITAHLGLFGRARLLADETIFVRGGTGGVGSMVVQMAKAAGANVITTGGSDEKVERCRELGADFAINYKTENLQERLAELAPDGLDVFWETIREPDFDFAVEALAPRGRMVLMAGRDARPEFPVGPFYVKECTVHGFVMFKASADEMKLAAEDINQWLASGQLKSQISQRLPLSQAAQSHRLQEAGTLAGDGSLAGKVVLTVGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVG7</accession>
    <name>A0A518IVG7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">tRNA-dihydrouridine synthase</fullName>
            <ecNumber evidence="10">1.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">dus_2</name>
        <name evidence="13" type="ORF">Mal33_30790</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 10">Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a 5,6-dihydrouridine in tRNA + NAD(+) = a uridine in tRNA + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:54452"/>
            <dbReference type="Rhea" id="RHEA-COMP:13339"/>
            <dbReference type="Rhea" id="RHEA-COMP:13887"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 5,6-dihydrouridine in tRNA + NADP(+) = a uridine in tRNA + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:23624"/>
            <dbReference type="Rhea" id="RHEA-COMP:13339"/>
            <dbReference type="Rhea" id="RHEA-COMP:13887"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3 10">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the dus family.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.-" evidence="10"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017150">
        <property type="term" value="F:tRNA dihydrouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02801">
        <property type="entry name" value="DUS_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035587">
        <property type="entry name" value="DUS-like_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001269">
        <property type="entry name" value="DUS_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024036">
        <property type="entry name" value="tRNA-dHydroUridine_Synthase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004652">
        <property type="entry name" value="tRNA_dU_NifR3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018517">
        <property type="entry name" value="tRNA_hU_synthase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01207">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006621">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00737">
        <property type="entry name" value="nifR3_yhdG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01136">
        <property type="entry name" value="UPF0034"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6 10" id="KW-0288">FMN</keyword>
    <keyword evidence="9 10 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="7 10" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Dus" evidence="12">
        <location>
            <begin position="1"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="11">
        <location>
            <position position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00002790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR006621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR006621-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="QDV57078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="322" mass="35858" checksum="B160FBE607022DDE" modified="2019-10-16" version="1">MAGFTNYAFRQIVREYGGVGLHATEMVNARGFVWLDENEAEHPDRLWGVREEARPLAVQIWDNQPDVMAKVGKRLVDDYQVSVVDINFGCPVKQVTEKAHSGSYLLKHPKTMYEIISRLVEACAPTPVTAKIRLGCTRNNVNCDDVAKVVEEAGAAALTVHGRTAQDFFSGNADWDRIAEIKQHLRSIPLIGNGDLDSADKVVAAFENYGVDGVMIARASLGRPWLFAQAHAALRGEPIPAEPTLELQRQCMLRHYDMIVERFGEAKGTVLMRKFACCYAQGKFGARHFRTHVARVSSASEFYSVVEEYFPRDLDAIEAAAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVV8</accession>
    <name>A0A518IVV8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">1,5-anhydro-D-fructose reductase</fullName>
            <ecNumber evidence="3">1.1.1.292</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">afr_7</name>
        <name evidence="3" type="ORF">Mal33_32210</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.1.292" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033712">
        <property type="term" value="F:1,5-anhydro-D-fructose reductase (1,5-anhydro-D-mannitol-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004104">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02894">
        <property type="entry name" value="GFO_IDH_MocA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GFO_IDH_MocA" evidence="1">
        <location>
            <begin position="3"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="GFO_IDH_MocA_C" evidence="2">
        <location>
            <begin position="136"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="318" mass="34471" checksum="5F5A1F125D97779F" modified="2019-10-16" version="1">MTIRWGLVGVGDIANKRVAAAIQSDPNSELVAVCRRSEPQLNQFADQFGVPHRFTNADDLIASPNLDAVYIATPVDCHCPQTIAAARAGKHVLVEKPMALNPAECDQMISACDQAGVSLGVAYYRRFYPVVLRIQQLIEAKQLGRILSIGCVTGNPNRFPADDWRVIRTRGGGGPLMDIGSHRLDVFLQLLGDVATVKANVIDSPDYEAEQAATLLVQFNSGAHGILQCYFGTVETPDRLEIIGTEGRITVEDLNHGDLMISTSEGQQLESHPPADNLHAPLISDFSAAVLEHRSPTISGPVGKRTNDLIRLAYEDAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IW43</accession>
    <name>A0A518IW43_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Outer membrane biogenesis protein BamB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_33100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018391">
        <property type="entry name" value="PQQ_beta_propeller_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002372">
        <property type="entry name" value="PQQ_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13360">
        <property type="entry name" value="PQQ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00564">
        <property type="entry name" value="PQQ"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="441" mass="47654" checksum="8777785C091DB6B0" modified="2019-10-16" version="1">MRRMPFHMRLMSIALLAMTGCSPKKVPVEEISGRVDLDDTAAAPIVVSEEDWNSWRGPSGNGIAADQEVPIRWSETENVIWKAKVPGRGHASPTVVGDQVFLASADERAETQFVVALDRSNGQQRWQTQVNQGGFAREVHAKGTQANSTLACDGEHVFAAFLHHDAIHVTAISIDGEIAWQTTVGAFNSKFGYAPSPLIYKTSVIIAADNRGGGYIAALDRSTGEPIWRKRRGAVSTYSSPIVGHVDGKDQLLITGGDAVTSYDPATGEENWSVPGTSEATCGTVVWDANHVYASGGYPDAHTLCIRVDGDATEVWSNRTKLYEPSMLVSDGFLYAVSDQGIGFCWDAETGAQMWKKRLGGNFSSALVLAGDKLFATADDGTCTVFAADNSDYIELARNRLDTDAYATPTICGGRIYFRVGQGDGPQRQEMLYCIGEPVEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IW61</accession>
    <name>A0A518IW61_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_33350</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="163"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="198"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="363" mass="39741" checksum="04AEFDB7B5C7CD60" modified="2019-10-16" version="1">MFRPAALPIHHPDDTPMIRRPRLLNKKRGSRRSGWQIWGTVGETLFFAALFLLGSFGVGLIIAIVTFATDQAPVTPGFGFWTLLIASISLIFLGTSGVTYRILGVGASHERRSALAKRAAEIELVPRGKLGKNDLPNVPQLKRITESPGTQLAFRLPTIASPIWNLAASAALAFMWTGCALSLLGVSIVSIVEGQPRVLLTILIVPISAAGIWTFRRFIIQLKKSAGIGLSIVEISNHPLQPGQTCEVYVAQYGRAALKSFQAKLVCEELSTFRQGTDVRTEKHAVFEEIVLAISGITIDPNQPWERKFTLAVPPSAMHSFQSPHNSISWWIVIHGEGSPWPSYFRRFPVVVLPHGATTATNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWE5</accession>
    <name>A0A518IWE5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_34190</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011463">
        <property type="entry name" value="DUF1569"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07606">
        <property type="entry name" value="DUF1569"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="151" mass="17039" checksum="CCBA114390B99509" modified="2019-10-16" version="1">MSRRKIHFENLSDAAAQCDQLLQSGYERNGNWSLAQICNHMRMTIDSSIDGYPKWMAIGKPLRPLLRWLMLPKLLRGDSPAGIKTASTFVPAEDLSDAEEVALFTESVRRFQTHTGYLHPHPGFGKFDHASLEQFHACHAAHHLGFLAARE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWF0</accession>
    <name>A0A518IWF0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">LL-diaminopimelate aminotransferase</fullName>
            <ecNumber evidence="2">2.6.1.83</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">dapL</name>
        <name evidence="2" type="ORF">Mal33_34230</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.6.1.83" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010285">
        <property type="term" value="F:L,L-diaminopimelate aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="1">
        <location>
            <begin position="55"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="419" mass="46048" checksum="2A00ABC395C5502B" modified="2019-10-16" version="1">MSTTNSETNSADPYFQSLFAERIGGSGYGKGTAIYKFEKIKRAKRKALADFPDRQLIDFGIGENDGVADAKVRERMAVEINQPENRGYADNGIGDFQQAVARFMQRNFNVTLDPAAEINHCIGSKTALSMLPACFINPGDITLMTAPGYPVAGTHTTYYGGTVHKLPLLAENNFLPDLDSITDEIWERVKILVLNYPNSPTGRLCPPEFFEKVVKLAKEKKFIVVQDAAHIMLTFDGRPTSFLETPGAKDVGVEVHSLSKGFDMIGWRLGWVCGNPTLVRAFSDVKDNCDSGQFIAIQKAAVTALDDESIPQRVNAKYRRRLEKLVTMLNECGFDCQMPGGSYFLYTKAPVASADGGSFDSGEAASQYLITQHSMVTVPWDDAGPYIRFSVTYEAADEAAEDALMAESKKRLMSAGLTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWH3</accession>
    <name>A0A518IWH3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator MprA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">mprA_4</name>
        <name evidence="3" type="ORF">Mal33_34520</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="7"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="138" mass="15531" checksum="ACE5505170E8C99C" modified="2019-10-16" version="1">MKLTKPNLLITDDDRAFRETLRSVLDRFDFEMYLAEDGEEALEIISRHQVHLALFDVHMPRLSGLEALTRMRASGLSLPCILMSAALDEAICDAASKLEDVSVIPKPLKIREISSVVTHLLAKRYGWQAESPAVDRPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWU2</accession>
    <name>A0A518IWU2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Bacterial regulatory protein, tetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_35680</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="12"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="245" mass="27702" checksum="D07C22E80948801E" modified="2019-10-16" version="1">MQSLTPKQQQIRQRESRILDLARPMIASGGISVLSMDAIAAELKTAKGTVYNHFPNKEEIVLALAIQAVECRLSLFNRAASLDGSPRQRVAAIGIACELFVDRFNELFRIEQIIRHDAVWDKTSPKRQALLRDCESRCMHTVATVVRDAMACGDLQTQQTHAIEDIVFGLWSLVYGGLMLELTSPSLADLGIENARRAIRRNCNGLLDGLQWQPLHDPKSYERWIKKVRTNLNQWLDKEHKLGES</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWX3</accession>
    <name>A0A518IWX3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glutamate dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">gdhA_2</name>
        <name evidence="9" type="ORF">Mal33_36010</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3 7">Belongs to the Glu/Leu/Phe/Val dehydrogenases family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004353">
        <property type="term" value="F:glutamate dehydrogenase [NAD(P)+] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01076">
        <property type="entry name" value="NAD_bind_1_Glu_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminiacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006095">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033524">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006096">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006097">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH_dimer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014362">
        <property type="entry name" value="Glu_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033922">
        <property type="entry name" value="NAD_bind_Glu_DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00208">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02812">
        <property type="entry name" value="ELFV_dehydrog_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000185">
        <property type="entry name" value="Glu_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00082">
        <property type="entry name" value="GLFDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00839">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="SSF53223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00074">
        <property type="entry name" value="GLFV_DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 3 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ELFV_dehydrog" evidence="8">
        <location>
            <begin position="178"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="102"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="216"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="345"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalysis" evidence="6">
        <location>
            <position position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000185-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000185-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000185-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV57590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="411" mass="45880" checksum="2804411314648DE8" modified="2019-10-16" version="1">MHAFEATQTYFNRATRHIDMSDSMRESLQMSKRELQVQVSFHKDDGSVMNCVGYRVQHNNSRGPMKGGLRFHHEVNLDEVRALASLMTWKTAVVDLPYGGAKGGIGVNPKTLSASEMERMTRAFVDQIHDVIGPDTDIPAPDMGTDHRTMAWIRNQWEKYHGFNPAVITGKPVEEYGAKGREEATGRGVGLLTFKLIKRKGRRPAESPIAIQGFGNVGSHAAKFLHEAEFPIVAVSDVSGTYYDPRGLDIPHLLRHTLMHKGSLEGFKECERLPGEALLQTDCEVLIPAALGGVITGENVDQIKAKIIIEAANGPIWPDADEQLNERDVIVLPDILANAGGVTVSYFEWVQNRQHYRWSLDRVRQELDRTLSEAFENVWHTSQEKNISLREAAFGVGIQRVKRATELSGSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXB0</accession>
    <name>A0A518IXB0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_37330</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="13"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="153" mass="17215" checksum="4787C170A823F831" modified="2019-10-16" version="1">MSDDIEAFLRRAAQRRKEQAARKAAPTAKPRPQYTDSRAERKIREQQVEEIVEPEIIEQADGFSQLSSRHLQAEHFAGGVGQADDKMDAHIQQVFDHQVSKLASEPADVSSQSQALADGEIAKALIDMLQTSNGVQQAFLLREIIERPTHRWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXF0</accession>
    <name>A0A518IXF0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_37780</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="225" mass="24763" checksum="DC796A0888E52F06" modified="2019-10-16" version="1">MKSATELINDEQRKRVEAAVVAAEAKTSCEIVPVVATSSGRYDRPEDMIGLWLAILAAITVWLMLPRQLDETGSWSGLPIYVGLLTMVASVVVAFIAGAWIGSRIGWLRRLFTPRQQMQEEVYARARQTFFDKRIHHTTGSTGLLIYVSLFEHIAVVLGDQEIIDKLGQSFLDQLCEQLTDGLRQGDASEAICNVITAAGEKLAGPLPRATDDVNELHDALVLID</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXQ9</accession>
    <name>A0A518IXQ9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_38860</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="137" mass="14110" checksum="5A840802A4F7E1D4" modified="2019-10-16" version="1">MNTDSASLRSSDIELVEPTPQLRIVSDSEAAELAAEIPTGSPFAPGTALPLDLVGQPISFEAGVWRETMLGGLLASLIMIAFGIGSLPIFPVGSMLIAGGGCLLGAMALVTRRPILAMAATIGNLAVLALGFVRSFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXT8</accession>
    <name>A0A518IXT8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Planctomycete cytochrome C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_39130</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011429">
        <property type="entry name" value="Cyt_c_Planctomycete-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011444">
        <property type="entry name" value="DUF1549"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022655">
        <property type="entry name" value="DUF1553"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07635">
        <property type="entry name" value="PSCyt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07583">
        <property type="entry name" value="PSCyt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07587">
        <property type="entry name" value="PSD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021888926" evidence="1">
        <location>
            <begin position="22"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="domain" description="PSCyt1" evidence="4">
        <location>
            <begin position="39"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="PSCyt2" evidence="2">
        <location>
            <begin position="162"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="domain" description="PSD1" evidence="3">
        <location>
            <begin position="445"/>
            <end position="703"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV57898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="749" mass="84132" checksum="917B863E9B73AA81" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IY06</accession>
    <name>A0A518IY06_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_39820</name>
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    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Rosistilla</taxon>
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    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="140" mass="14423" checksum="F28BF7C054506D10" modified="2019-10-16" version="1">MRPFEFRVVGLIALGLLVTGGCSSESGPERRVVTGRVTFQGEVVPSGEIRIAPEGDGPVSAAQISNGVFEIAQRGGVVIGPAKVMIVAVPSAAGVSQDELDRGGAQPKTMAIPAKYNEDSVLSAEIEAGEGAQTIDFDLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYA2</accession>
    <name>A0A518IYA2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Chromosome partition protein Smc</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">smc_5</name>
        <name evidence="7" type="ORF">Mal33_40790</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011429">
        <property type="entry name" value="Cyt_c_Planctomycete-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07635">
        <property type="entry name" value="PSCyt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021944122" evidence="5">
        <location>
            <begin position="20"/>
            <end position="1089"/>
        </location>
    </feature>
    <feature type="domain" description="PSCyt1" evidence="6">
        <location>
            <begin position="44"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="292"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="334"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="376"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="476"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="693"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="947"/>
            <end position="1079"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV58062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1089" mass="114064" checksum="49DD24D9853AFF49" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYG4</accession>
    <name>A0A518IYG4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Magnesium and cobalt efflux protein CorC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">corC_1</name>
        <name evidence="12" type="ORF">Mal33_41480</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04590">
        <property type="entry name" value="CBS_pair_CorC_HlyC_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002550">
        <property type="entry name" value="CNNM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044751">
        <property type="entry name" value="Ion_transp-like_CBS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005170">
        <property type="entry name" value="Transptr-assoc_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03471">
        <property type="entry name" value="CorC_HlyC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01595">
        <property type="entry name" value="DUF21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01091">
        <property type="entry name" value="CorC_HlyC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51846">
        <property type="entry name" value="CNNM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0129">CBS domain</keyword>
    <keyword evidence="6 8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="100"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="141"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="CNNM transmembrane" evidence="11">
        <location>
            <begin position="1"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="10">
        <location>
            <begin position="222"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="10">
        <location>
            <begin position="285"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QDV58131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="449" mass="49353" checksum="92FF3609EA7A2C94" modified="2019-10-16" version="1">MENWINFGIALLLVVINGFFVAAEFALVKARPSRLEQMALGGNLFAKVASWLARRLDASLSACQLGITLASLALGWVGEPAFHHLIEPVFAGIGISNPDVLHVVSLVFAFTTITALHLVIGEQAPKIFAIRKPEPMAVWCALPLAGFYYVAYPLLVALNWITSLLLRSIGVDAVDEHGTPHTEEELRNLVAQSHVHGELTRSEAQLINAVLEFDDQSAHQIMTPRTDVVTLSMDAPIEDWITTIRKYRFSRYPVVEQSLEKAVGVLHIQHLVGLDLSQPLDRAALLQPPNFVPETIPIKTLLQHFKSSQSLLAFVVDEHGTVVGVVTLEDVLEELVGELEDEFDEQVRDIVREDDQTFRVLGQTPLDDINKMMGLTLQSHDSDSLGGFVMQQLGRVAEQGDVIQIDGAKIEILRVEGPRIVSLRVRLAAPLASLDAAPSTDEEEDSAAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYP9</accession>
    <name>A0A518IYP9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Deoxyguanosinetriphosphate triphosphohydrolase-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">dgt</name>
        <name evidence="3" type="ORF">Mal33_42320</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the dGTPase family. Type 2 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016793">
        <property type="term" value="F:triphosphoric monoester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01212">
        <property type="entry name" value="dGTPase_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006261">
        <property type="entry name" value="dNTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023023">
        <property type="entry name" value="dNTPase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026875">
        <property type="entry name" value="PHydrolase_assoc_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13286">
        <property type="entry name" value="HD_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01353">
        <property type="entry name" value="dGTP_triPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51831">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD" evidence="2">
        <location>
            <begin position="76"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="380" mass="43148" checksum="749CB71FD5A1F637" modified="2019-10-16" version="1">MNDSVPHPSDREDGLLASYAMHSNDSLGRKHPESTHAYRGPFQRDRDRILHCSAFRRLAGKMQVFTGDMGDYHRTRLTHTFEVASIARTIGRVLRLNEDLIEALALMHDIGHPPYGHCGEDVLHDCMRQAGGFSHNQFALTIVEDLEQRFNRFSGLNLSAEVLAGQTARANKHQPANVTAPLLEVQVVDAADSMAYDAHDIDDAVQLGLLTIEELARVPLVERALRSIEAKYRNLPPKQLRPALVHELVDLQVSNFLEFNIPRIHAAQGKTAAEVREEGLRVEEDESFRSERRELEKFLFDNIYRHSRLLEIRRSAGQRLEQLHSRLVDQPDRLPLRFRQRASSVGPIRAVGEYIAGMTDRFCDLQHEYLFSGAGPLADW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYY6</accession>
    <name>A0A518IYY6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HTH-type transcriptional regulator IscR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">iscR</name>
        <name evidence="1" type="ORF">Mal33_43230</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030489">
        <property type="entry name" value="TR_Rrf2-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000944">
        <property type="entry name" value="Tscrpt_reg_Rrf2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33221">
        <property type="entry name" value="PTHR33221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02082">
        <property type="entry name" value="Rrf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00738">
        <property type="entry name" value="rrf2_super"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01332">
        <property type="entry name" value="HTH_RRF2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51197">
        <property type="entry name" value="HTH_RRF2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="139" mass="14720" checksum="4AF25AF003ED36D9" modified="2019-10-16" version="1">MLSKTAEYALRAVACLGAQPGTTSPADALAEKTKVPRRYLNRVLQDLAAAGLVQSRPGPGGGYLLARETGEVTILEVVNAVGPLERIRKCPLGLASHTQLCPLHAELDRAYAATEEAFQGVTIKQLVESTSPIVPLCEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYZ9</accession>
    <name>A0A518IYZ9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_43260</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021788637" evidence="2">
        <location>
            <begin position="22"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="53" mass="5609" checksum="408986DBA8D78200" modified="2019-10-16" version="1" precursor="true">MNLTRTGLSILLLSFVFVAGCQEQPADPNDNYTPTPDIETPSPGGMESTPTPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ51</accession>
    <name>A0A518IZ51_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FHA domain-containing protein FhaB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">fhaB</name>
        <name evidence="3" type="ORF">Mal33_43840</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00060">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SSF49879"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="215"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="FHA" evidence="2">
        <location>
            <begin position="16"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="domain" description="FHA" evidence="2">
        <location>
            <begin position="98"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="254" mass="27805" checksum="0903C06B96B1432D" modified="2019-10-16" version="1">MTIEPVNNIEPSNRSWLIGSGDDCDVVIDHPKVSKHHCQLTRTGDRLSIQDVNSENGTWIDGVPYVGPKPIRRGSSIMLGETVEMLWPVDLIEFKSVIAIGRSQDNDVVLDKPNVSGRHARLIDDGTALWIEDCGSTNGVALNRPDNLVRHHRVVSGDAIYLGSTRITIDRILQVGLACESVNGQEFADRLAEKMLTTTLVSDAERARQRKFRSALMTCVAIGSILFGAACAVYFAKLTEPAGKSSERVPNAVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ86</accession>
    <name>A0A518IZ86_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Sorbitol dehydrogenase</fullName>
            <ecNumber evidence="4">1.1.1.14</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">gutB</name>
        <name evidence="4" type="ORF">Mal33_44260</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.14" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003939">
        <property type="term" value="F:L-iditol 2-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="PKS_ER" evidence="3">
        <location>
            <begin position="7"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV58408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="346" mass="36316" checksum="8D6CEEC85746E41A" modified="2019-10-16" version="1">MKAMLLTEYKKLELAEIPVPELGPDDVLVQVKACGICGSDIHGYDGSTGRRIPPLVMGHEASGVVASVGSGVSDLPAGTRVTFDSMVWCGKCHFCRRGEMNLCDNRRVLGVSCGEYRQYGAFAEYVAVPRHIVYELPDAVSFEQAALIEAISVAVHAAERTPVSLGDTAVVVGSGMIGLLVIQAIKLAGCSRVIATDLNANRLEVAKTLGADVTIDASKEDVVARVAELTGGRGADVALEVVGATPTVKTAIDSVRKGGTVTLVGNISPNIDLPLQSVVTRELNVLGSCASSGEYPACIKLLETGQIQVEPLITAKATLEEGPAWFERLYAGEPEAMKVLICPAGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ95</accession>
    <name>A0A518IZ95_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glutamine synthetase 1</fullName>
            <ecNumber evidence="4">6.3.1.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">glnA1</name>
        <name evidence="4" type="ORF">Mal33_44240</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the glutamine synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.1.2" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004356">
        <property type="term" value="F:glutamate-ammonia ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006542">
        <property type="term" value="P:glutamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008147">
        <property type="entry name" value="Gln_synt_b-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036651">
        <property type="entry name" value="Gln_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008146">
        <property type="entry name" value="Gln_synth_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004809">
        <property type="entry name" value="Gln_synth_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027302">
        <property type="entry name" value="Gln_synth_N_conserv_site"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00120">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03951">
        <property type="entry name" value="Gln-synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01230">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54368">
        <property type="entry name" value="SSF54368"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="SSF55931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00653">
        <property type="entry name" value="GlnA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00180">
        <property type="entry name" value="GLNA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gln-synt_C" evidence="3">
        <location>
            <begin position="106"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV58406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="474" mass="52761" checksum="9FFA450E3B698331" modified="2019-10-16" version="1">MASVKTPQDVLSMCRQHDVKAVDFRFTDFLGVWHHKTVPVSELTEDLFEDGTGFDGSSLHGWQAVHESDMLLVPQPETAFLDPFTNLTTLNLICNVQDPITADSYPRDPRYIARKAVGYLTSTGIADTAYIGAEAEFFVLDDVRYDLTSQGSFYSIDSNEAPWNRGRMESPNLGHKMRTQAGYFPCPPSDQLFDLRNEIMQTLTDVGLSVECHHHEVGAAGQCEIDLRFDQLTRTADMMMIYKYIVKNVARRNGKTATFMPKPIAGEFGSGMHTHLSLWKDGDPLFAGSGYAGLSDLAVHAIGGILHHAPALLAFTNPTTNSYRRLLPGFEAPVHLAYGRSNRSAACRVPMYSTNPKTKRVEFRCPDPSCNPYLAFSAILMAMIDGIVNRINPGEPMDKDLFQVPAEELPELASTPTTLEEALVALEADNDFLRVGDVFSEDVLTSWIKTKRELEIAPTRSQPTPLEYCLYFDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZD0</accession>
    <name>A0A518IZD0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_44760</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="278"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="316"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="364"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="406" mass="44521" checksum="B6C7C988C9BB5FAE" modified="2019-10-16" version="1">MLHSPAATPSADGLIEIGVIIAGPLDDVDRQSASRAIEQTRRDLSEMMPEFRFRMLQSRRPELASEGRTQPSVLLQQAAEERDARHWDFVIVCTASDLVGNYAPFCFAALSRPLDAAVISLSLIDPPAIHDKAETKARIRAIAHRTSRLMLHAIGHLNGLSGQESPQNLMFRPATAEEIDAMQELDPPQIDAMHDAMAEIADQRLEESTSRPASRIAFLVRAAWINRREIAQAVIGARPWQFPRHLSRLTIAAVSTVAILLMTAEAWDLGLSQTAGEVATLALASLILTTIYVVFRQQLLVRRGRQHTEQTVVTSTSALAIVLLGMSVTWIVLMVIGVSFSWLLFDGDLIAAWAGSNEIQAGEIGLATFVRMSGFSASLGLLIGALGASFESQHYFRHIIFVDEEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZE2</accession>
    <name>A0A518IZE2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Chaperonin GroEL</fullName>
            <ecNumber evidence="3">5.6.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">60 kDa chaperonin</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Chaperonin-60</fullName>
            <shortName evidence="3">Cpn60</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">groL5_1</name>
        <name evidence="3" type="synonym">groEL</name>
        <name evidence="3" type="synonym">groL</name>
        <name evidence="6" type="ORF">Mal33_44850</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 5">Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 5">Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3 4">Belongs to the chaperonin (HSP60) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="5.6.1.7" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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    <sequence length="571" mass="60252" checksum="C031C7317E3309E8" modified="2019-10-16" version="1"> </sequence>
</entry>
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            <authorList>
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                <person name="Heuer A."/>
                <person name="Rast P."/>
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</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Rohde M."/>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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        </location>
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    </feature>
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    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
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        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Pinto D."/>
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                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
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                <person name="Bruemmer F."/>
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                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8 9">Mal33</strain>
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    </dbReference>
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    </dbReference>
    <dbReference type="Pfam" id="PF02812">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="SSF53223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ELFV_dehydrog" evidence="7">
        <location>
            <begin position="203"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="126"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="165"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="210"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="241"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="377"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalysis" evidence="5">
        <location>
            <position position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000185-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000185-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000185-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV58592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="445" mass="48720" checksum="303699814CB477AC" modified="2019-10-16" version="1">MDEKLESVFWNVQQRNQGEAEFIQAVKEVLSSMGPVLAKYPTFAEQKIIERICEPERQIIFRVPWQDDRGEVHINRGFRVQFNSALGPYKGGLRFHPSVNLSIIKFLGFEQIFKNALTGMPIGGAKGGSDFDPKGRSDSEVMRFCQSFMTELYRHIGEYTDVPAGDIGVGKREVGYLFGQYKRICNRYESGVLTGKGLHYGGALVRTEATGYGLVYFVQEMLAARSDSLQGKTCVVSGAGNVAIYAIEKVTELGGRVVACSDSTGVIYDQEGIDLPTLKKIKEVDRLPIEKYCETRKHAKYQRKGNIWQIECDVALPCATQNELTGKDAASLIQNGCIVVAEGANMPTTPQGIELLLGSKIGYAPGKAANAGGVATSALEMQQNASRDAWSFEYTDRKLALIMKDIHDRCLETADEFGAPGNYALGANIAGFMGVADAIQSMGLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZW5</accession>
    <name>A0A518IZW5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">dTDP-4-dehydrorhamnose reductase</fullName>
            <ecNumber evidence="2">1.1.1.133</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rmlD</name>
        <name evidence="2" type="ORF">Mal33_45980</name>
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    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.1.133" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008831">
        <property type="term" value="F:dTDP-4-dehydrorhamnose reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029903">
        <property type="entry name" value="RmlD-like-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04321">
        <property type="entry name" value="RmlD_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RmlD_sub_bind" evidence="1">
        <location>
            <begin position="10"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="344" mass="38080" checksum="5CCE3C750E85803A" modified="2019-10-16" version="1">MDAEIPLPLIVTGIAGVAGYNAFRYLRARFPGQVYGVRREDNWPLSGDGILGCNSDDFDRWQQIIDQIQPAAVLNCEGSCALKSCELDPQMAERINVTSVENLIRVLAPTTRFIHLSIDLVFSGDKDGGYTEEDTPDPVTVYGKTMVAAERLVLERRPDACVLRISLPMGISFNGHAGAIDWIQSRFKNGRPATLYFDEVRTPTYTDCLNLVVERLLGNDLAGLYHCGGPRNLSLYEIAQVINRVGGYDPKLLMGCPRIDAGPMPPRAGNVTMDSSRLIAALGDEVFHPWPLDCSMVPSDVDWHHDRSTLQGSPELLADVLYRNPRRVDSMPEFENIDSPSSSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZX5</accession>
    <name>A0A518IZX5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">BNR/Asp-box repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_46630</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011040">
        <property type="entry name" value="Sialidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036278">
        <property type="entry name" value="Sialidase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13088">
        <property type="entry name" value="BNR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50939">
        <property type="entry name" value="SSF50939"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021957144" evidence="1">
        <location>
            <begin position="25"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="domain" description="Sialidase" evidence="2">
        <location>
            <begin position="48"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="388" mass="42290" checksum="152D7C9E4E54F82A" modified="2019-10-16" version="1" precursor="true">MSKRLIVSSICLFLGLGFAQLANAEEQPDLPIVDVADQTERHVTIAAGTPAVYQGHPTTLLMPDGKTIFAVWCINHGGAAGPMAKSTDGGLNWSRLDKQLPAGFSTHQNCPSIYRMVGPDKKERLWVWSAALGKRGGPGMPSIMSEDGGANWKEMPPLGFPCVMTFSSVLQRKDGSYIGFFHKGPDGKDRTPLKVLQTVTNDGGFTWSEPEVVAAVEGKNPCEPFALRSPDGKQICVLMRENTHRGRSLMMFSEDEGESWSEPVDTSWGLTGDRHIGVQLDDGRWVIAFRDVAINSPTRGDFVAWVGTYDDIRQGKPGQYRIKLLQNYAANRLDCGYPGVELLPDGTIVATTYVKYAPGPEKHSVVSTRFKIAETDALASQSDNAASK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J029</accession>
    <name>A0A518J029_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_47250</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002105">
        <property type="entry name" value="Dockerin_1_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036439">
        <property type="entry name" value="Dockerin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00404">
        <property type="entry name" value="Dockerin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63446">
        <property type="entry name" value="SSF63446"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="574" mass="61733" checksum="E5A1843246B29131" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J036</accession>
    <name>A0A518J036_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Serine-aspartate repeat-containing protein C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">sdrC_1</name>
        <name evidence="4" type="ORF">Mal33_47230</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4 5">Mal33</strain>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="entry name" value="Ig-like_fold"/>
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        <property type="entry name" value="Dockerin_1"/>
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            <begin position="236"/>
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            <end position="23"/>
        </location>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="QDV58699.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="703" mass="74179" checksum="98AA0C216B91631D" modified="2019-10-16" version="1"> </sequence>
</entry>
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            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
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                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
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                <person name="Jeske O."/>
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                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
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                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
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                <person name="Jetten M.S.M."/>
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                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="1 2">Mal33</strain>
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        <source>
            <dbReference type="EMBL" id="QDV58708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="235" mass="27162" checksum="E3217480547AD248" modified="2019-10-16" version="1">MSLTSLLDKIAGRQQQRRLSKWSDYKTLVAEICDGKEPDDDKVATVLADNEKSLDELRDDAKLLARRRKLRAEMDAIEPLESEAVKVDRKISEAEQAFEAMTAKHEEQTSPLYIRRNEIKAIRKRATQARSELRDSCEDRELVSAYESVLEDLHEAQHERAGIDEEITKRESWIRQDKEKAEVTHVVQEQRRYRSQAKEHERILADLKATREPVTQTVGQLGSQLSMIENQLLVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
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        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
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    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
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                <person name="Jeske O."/>
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                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
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                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
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    </dbReference>
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            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021810617" evidence="1">
        <location>
            <begin position="31"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="205" mass="22045" checksum="51BE74F2B7A9805A" modified="2019-10-16" version="1" precursor="true">MNLRCRKPIAAGLFGMVMMLAVGCSSNNNAATEGNADEQVAAAIVAGQIPSDAAKEKMLAAKEALFTTLSGRLMEAINRQGPAAAIAVCQKEAPKIAERVGEEQGLRIGRTGVRLRNTNNVAPSWAEDLVRDKIDTPTFVVLDNGHSAALLPIKLQGKCLMCHGPQDQIAPAIQEQLTKLYPHDRATGFNEGDLRGWFWIDLPNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0M9</accession>
    <name>A0A518J0M9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">yjcD</name>
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    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Pinto D."/>
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                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
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                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
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        <property type="match status" value="3"/>
    </dbReference>
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        <property type="entry name" value="DNA_helicase_UvrD-like_C"/>
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        <property type="entry name" value="DNA_helicase_UvrD/REP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
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        <property type="entry name" value="UvrD-like_ATP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11070">
        <property type="entry name" value="PTHR11070"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00580">
        <property type="entry name" value="UvrD-helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13361">
        <property type="entry name" value="UvrD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="UVRD_HELICASE_ATP_BIND"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="UVRD_HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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        </location>
        <ligand>
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        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
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    </evidence>
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        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS51198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV58901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="916" mass="101725" checksum="4ABE018F3AFBCDDB" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0N8</accession>
    <name>A0A518J0N8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
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    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetes</taxon>
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            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="64" mass="7692" checksum="081505E723289783" modified="2019-10-16" version="1">MKRIQSMWRATRILWAILLVIGIALPWIDPIMFTIWLINIPICIGVFFYFAYVRYDEDGNDLER</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0V4</accession>
    <name>A0A518J0V4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative 2-keto-3-deoxy-galactonate aldolase YagE</fullName>
            <ecNumber evidence="2">4.1.2.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">yagE_4</name>
        <name evidence="2" type="ORF">Mal33_50010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DapA family.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.-" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002220">
        <property type="entry name" value="DapA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12128">
        <property type="entry name" value="PTHR12128"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00701">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001365">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00146">
        <property type="entry name" value="DHPICSNTHASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01130">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR001365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="304" mass="33549" checksum="8CC6969698180ADF" modified="2019-10-16" version="1">MSTRLISAICTPLQSDGSLHEPGLAAHIDAQLDAGINGLLVAGTMGLMQLQTDATYQRLIEESVRVNAGRSEIWIGVGDLSYQRTLERIRVAEQHAVDGLVVLTPYLMKFSEQELIHYYLKLADASTKPLFLYDLPVLTGTALSMELVEQVTAHPNIHGLKCTRDWEWTTELWNRFGSRTRVVPAQPERVADLVRMQVPDNLDGLFAIFPKLSRALADAADAGQWEEAARLQADLSSYLTIAREISLFGAVTATLNALGTEGLMAPEPYYQLSQEEREAFLSEPTIRRLIDTESACTSVTSNAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J102</accession>
    <name>A0A518J102_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Polysaccharide deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_50100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="SSF88713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NodB homology" evidence="1">
        <location>
            <begin position="89"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="291" mass="33425" checksum="2B5A01A7E8D08444" modified="2019-10-16" version="1">MPNLRQLAIDFRRVVSTPCRQLQLRRLSAKGKAPISVLFYHRVADEQPNDWTIPCDLFQEQMEWIRERFDVIDMQEVQRRIRQQDSRRPAVHITFDDGYAENCRFALPYLIRNKMPCTYFVSYGNCVTGDPFPHDVAAGCPLPVNSLDELKALAGTSVEIGYHTRTHCDCGNLITADDFRDEITDGAAEMRAALDMPLRYFAFPYGLPDNIPIAGIQAAYEAGFQGFCSAYGAYNLPGQDAFHIRRIHGDAEMSRFKNWLSFDARKLHQRPEIRYWLPPANNWEQTLELVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J106</accession>
    <name>A0A518J106_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_50510</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="198" mass="22027" checksum="8DB5B6FC3CD9BF4D" modified="2019-10-16" version="1">MAAQGDLATTKRGHRHSGASVGYLISSVSSPIRTSTRSIDSIASIRSSQIESLIERNYVSNRREQVSVDIEQKNRKASKRSNRSLPGYRKRSSDRTQIVYLRPRSKVKSVVWPVPFSSMNRSGKRLGAIFRESKRRRRSRNQTATSSGRRSGCSRSGRFCSNNVCDNRVAAVDLPFVNALSATPRSSLGYPPTSFSNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J169</accession>
    <name>A0A518J169_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase</fullName>
            <ecNumber evidence="2">2.7.1.49</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">thiD</name>
        <name evidence="2" type="ORF">Mal33_51020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.1.49" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008902">
        <property type="term" value="F:hydroxymethylpyrimidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008972">
        <property type="term" value="F:phosphomethylpyrimidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01169">
        <property type="entry name" value="HMPP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045029">
        <property type="entry name" value="HMP/HMP-P_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004399">
        <property type="entry name" value="HMP/HMP-P_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013749">
        <property type="entry name" value="PM/HMP-P_kinase-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20858">
        <property type="entry name" value="PTHR20858"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08543">
        <property type="entry name" value="Phos_pyr_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00097">
        <property type="entry name" value="HMP-P_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phos_pyr_kin" evidence="1">
        <location>
            <begin position="11"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="254" mass="27070" checksum="8259135F78B7683D" modified="2019-10-16" version="1">MHVALTIAGSDPSGGAGLQADLKTFHAHRVYGTSVVTLLTVQNTQTVDAIEQMNPEFVLAQLDAVLDDIPPTAAKTGALGSAAMIHAVAERASSFHFPLVVDPVMISKHRVPLLDDASIDVLRRELLPHAFLVTPNRMEAARLANIEVDDLESMQMAAQMIHQLGAKNVLVKGGQVGSESVDWLFTANKFHRIGGERIDTRSTHGTGCVLSAAITASLAQNMPLVEAVEQAKLYVVNAIRTAPNLGKGYGPVNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1F8</accession>
    <name>A0A518J1F8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">tRNA threonylcarbamoyladenosine biosynthesis protein TsaE</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaE</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">tsaE</name>
        <name evidence="5" type="ORF">Mal33_52090</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TsaE family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002949">
        <property type="term" value="P:tRNA threonylcarbamoyladenosine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003442">
        <property type="entry name" value="T6A_TsaE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02367">
        <property type="entry name" value="TsaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00150">
        <property type="entry name" value="T6A_YjeE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00032441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV59181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="158" mass="17694" checksum="8E7A355E5103CD6D" modified="2019-10-16" version="1">MHNHQLCRMSIHSLDDTDRLGRMLAQRLPDRATIGLVGTLGAGKTRLVQSVAAAIGVPEGTATSPTFTLIQPYHAANRRIYHVDAYRVNDLGEFLELGIEELMEEPGAWVFVEWGDRVADVFPDETLWLRIEVVSPTQREVTFFGDPAVWESLFSNSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1G4</accession>
    <name>A0A518J1G4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Acetyl-coenzyme A synthetase</fullName>
            <shortName evidence="5">AcCoA synthetase</shortName>
            <shortName evidence="5">Acs</shortName>
            <ecNumber evidence="5">6.2.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Acetate--CoA ligase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Acyl-activating enzyme</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 9" type="primary">acsA</name>
        <name evidence="9" type="ORF">Mal33_51950</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>acetate + ATP + CoA = acetyl-CoA + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:23176"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.2.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="PTM">
        <text evidence="5">Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.1" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003987">
        <property type="term" value="F:acetate-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016208">
        <property type="term" value="F:AMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019427">
        <property type="term" value="P:acetyl-CoA biosynthetic process from acetate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01123">
        <property type="entry name" value="Ac_CoA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011904">
        <property type="entry name" value="Ac_CoA_lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032387">
        <property type="entry name" value="ACAS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16177">
        <property type="entry name" value="ACAS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02188">
        <property type="entry name" value="Ac_CoA_lig_AcsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0007">Acetylation</keyword>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 5 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ACAS_N" evidence="8">
        <location>
            <begin position="37"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding" evidence="6">
        <location>
            <begin position="95"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding_C" evidence="7">
        <location>
            <begin position="540"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="region of interest" description="Coenzyme A binding" evidence="5">
        <location>
            <begin position="201"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="320"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="344"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="396"/>
            <end position="398"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="420"/>
            <end position="425"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="509"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="524"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="532"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="535"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="546"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="548"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="551"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="592"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-acetyllysine" evidence="5">
        <location>
            <position position="617"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF16177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV59167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="654" mass="72385" checksum="1543DB69D466FF1F" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1I8</accession>
    <name>A0A518J1I8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Ribosomal protein S6 modification protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">rimK_2</name>
        <name evidence="12" type="ORF">Mal33_52310</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013651">
        <property type="entry name" value="ATP-grasp_RimK-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006037">
        <property type="entry name" value="RCK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036721">
        <property type="entry name" value="RCK_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041107">
        <property type="entry name" value="Rimk_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004666">
        <property type="entry name" value="RpS6_RimK/Lys_biosynth_LsyX"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08443">
        <property type="entry name" value="RimK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18030">
        <property type="entry name" value="Rimk_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02080">
        <property type="entry name" value="TrkA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116726">
        <property type="entry name" value="SSF116726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00768">
        <property type="entry name" value="rimK_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51202">
        <property type="entry name" value="RCK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0464">Manganese</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="10">
        <location>
            <begin position="104"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="domain" description="RCK C-terminal" evidence="11">
        <location>
            <begin position="296"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="375"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QDV59203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="417" mass="46099" checksum="D88A1CFA0C8052D0" modified="2019-10-16" version="1">MKLAILSCSLGCYSTRRLRESAIARGHSVKVLNTLKFSIDVEQGVPELYFRSKRLSHYDAVLPRIGSSITYFGTAVVRQFEQMDVFCANSSNGISNSRDKLRSLQILSRHQIGIPQTTFVRDRKDVLPAIDRIGGAPVIIKLLEGTQGVGVILADNVKVAEAIIETLHSTRQNVLVQKFVSESKGRDIRAFVVGDQVVAAMRRVAQGSEFRSNVHRGGRTEPVELDETYCQVAIRAAQIMGLRVAGVDMLEGNDGPQVMEVNSSPGLEGIESCTQLDIAGAIIDYMAAQVDFPEIDLRQRLTVSRGYGVTEIYIPEGSEYVGKTIDESGLPEMDINVLTLYRGTTVIPNPRLKRSLEPSDRLLCFGKLDHMRSMVPERTRRKRRPVVKVLPPNSDRPDSETAAAAQDEPVVAPEEEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1P8</accession>
    <name>A0A518J1P8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GYF_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_52920</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035445">
        <property type="entry name" value="GYF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025640">
        <property type="entry name" value="GYF_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14237">
        <property type="entry name" value="GYF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55277">
        <property type="entry name" value="SSF55277"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="287"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="domain" description="GYF_2" evidence="3">
        <location>
            <begin position="176"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV59264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="313" mass="33268" checksum="933F4A1028956BAA" modified="2019-10-16" version="1">MGIRFHCHECQHRLNVKEFLAGKRGKCPRCKVSFRIPMGDQELSIPIDLDSPESNDSPASDDSSADEAPAAAAEKSSPAPDPAPAKPATASSVDRAPVAAAPEASPAKDSRADQPAKKAAPSPEPAELASVSEPAVSKSNVPTDPPPPSIATPDQSQHETSQDESSPMAVAGDVVWYVRPPSGGQYGPAGGSLLQQWIKEHRVVPGSLVWRDGWAQWRAAEEVFGPKFATLGVADIDLNADLPESPLAVNEPIRSTDSSAAVDLQPQPSPTEFERRQMAKRKRRTRMIAMLAGVSLFLIVVIILVVVSKSVDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1T9</accession>
    <name>A0A518J1T9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_53330</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="110" mass="11831" checksum="3E1CC5FD0DFE9049" modified="2019-10-16" version="1">MVALTLQWTCVARLVALAFTLSRRSRGRVGKRASSVFPGEGGFQGTCAVDLVSTPLSELRFACSTLPFKLRLGRVKCGCFDIAMDLCDATGIGQLHPLAAKPWEGRETSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1V0</accession>
    <name>A0A518J1V0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytochrome bd-I ubiquinol oxidase subunit 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">cydB</name>
        <name evidence="8" type="ORF">Mal33_53360</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome ubiquinol oxidase subunit 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003317">
        <property type="entry name" value="Cyt-d_oxidase_su2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43141">
        <property type="entry name" value="PTHR43141"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02322">
        <property type="entry name" value="Cyt_bd_oxida_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000267">
        <property type="entry name" value="Cyt_oxidse_sub2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00203">
        <property type="entry name" value="cydB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="85"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="117"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="160"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="197"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="231"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="260"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="304"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV59308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="342" mass="37982" checksum="9B34AFE3A6F20942" modified="2019-10-16" version="1">MNYELLTFIWFVLLGVLLCGYAILDGFDLGVGILHPFIAKDDTQRRLVMNSIGPLWDGNEVWLVTFGGALFAAFPVAYATVFSSFYLAFFLLLTCLIGRAVSLEFRSKVQSPRWRKAWDFGFFASSLTAAALLGIAGGNVMAGMELGPRYVYEGGLLSQIYWYPLLVGALTVSLFAMHGAIYLYLKTEDELQARVRRAIHPLFLTFAGLYVVVTLATWLHVPHATENIANYPVLWIVPVLNFLAVLNIPRAMYLNRPGYAFFSSAMVILAFASLFSVAIFPNLMLSTIDPAYSVTLENARSSHATLGTMLIIAAIGLPCVLSYTVIIYWIFHGKVKLDPHSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1V9</accession>
    <name>A0A518J1V9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Colanic acid biosynthesis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_53460</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007345">
        <property type="entry name" value="Polysacch_pyruvyl_Trfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04230">
        <property type="entry name" value="PS_pyruv_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PS_pyruv_trans" evidence="1">
        <location>
            <begin position="45"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="383" mass="43103" checksum="3F6C18561E3841A1" modified="2019-10-16" version="1">MKFVEVTGTNFQNKGAELMLGAIASKCLQSADLRCAIQPWNGSFEKRARLGVYQKADFQRFRIKWHCLASLIPKRVRQQYGIVVDAEISAVLDASGFQFGDQWGAAICRSAANRLKASKRKGKKIILLPQAFGPFQDAGTREAMKHILDVCDLVFARDPSSLGHLTKLETNESVIRMAPDFTNLVGREPSATQEKWGVCILPNQRMLDKSPRKTSAKYIEFLVDAARLLNEQSQNPFFLIHETTTDRSIVDEVNDRLDVPLPLIEESDIFRIKEILGSCQAVVGARYHGLVSALSQGVPCIATGWSHKYVHLMRDYACEDYFVDLSISDQKSRLAELIDTDRLRDCKKRVVGCATHLKHQSEAMWNEVFRVLSAETEPLPTRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1W5</accession>
    <name>A0A518J1W5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_53510</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="36" mass="4180" checksum="5F6F6AF6FC323F71" modified="2019-10-16" version="1">MTDPFPRKLPFIRGKPRQLVTEILSVVKHSKNISFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J243</accession>
    <name>A0A518J243_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">stkP_3</name>
        <name evidence="10" type="ORF">Mal33_54500</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="426"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="78"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="368"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="371"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="107"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV59415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="453" mass="48288" checksum="AF6E739316F1573F" modified="2019-10-16" version="1">MSHKTHLSDAKTAFQASALTSELITSAQLAEAVAALRAGGQKVDDKLLAAALVRDGLLTGYQAEQLKAGRTKLNLGPYIITDFIGQGGMGQVFKGVHKVMGRECAVKVLPLQKVTDETRNNFLHEIRMQAGLDCQYLVRAFDAGKDGQIHYLVTEYVPGTDLRRHIKKNGALPVSEAALYIHQAALGLDYAHQQGLVHRDVKPGNILVTPRGRAKVSDVGLAAWSTAMSSDPRAGKIVGTADYLSPEQILTPDNIGPASDIYGLGCTLYYCICGKVPYPGGNTASKCRRHCEDLPMHPRKFAEDIPEEFVDIIADMMEKDPNDRIASAAEVAARLEPWLEDVQALGDRPITRGPWLEPPPPGVDPYSGTGIAGQGSGQISASGDANDSTAASVGDTMNSASGIVPPPPMPGYEIAISSKPNTGMQVAIALAIAIPFSLMIGAIIGFYVHDKLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J271</accession>
    <name>A0A518J271_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cobalt-zinc-cadmium resistance protein CzcC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">czcC_3</name>
        <name evidence="3" type="ORF">Mal33_54610</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021818454" evidence="2">
        <location>
            <begin position="21"/>
            <end position="524"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV59426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="524" mass="56316" checksum="ABA9E2835A6F7C7B" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J294</accession>
    <name>A0A518J294_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_54910</name>
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        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
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            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="459" mass="51704" checksum="4BC0BFE34A75E9E3" modified="2019-10-16" version="1">MLNQFLSEIQNGEIAFPLVELTLHRGDGQQHVGTGHLVWTQDGCRLHAVTDGGSILQREFGRFPGRPGEIIPENQYLSMNGRTQDGWRFTVERLDRSGYHVHSGRETIVWRIANDGFRSHVTYERERSTGDVASAAYVAIASGLEFGSWPRSTETRVENPAFGNQRQERDWLQFPTSFGDVAVRKVNSDLTMIRVSEVKRSQLTEARAAIQAALSYVDGRRCEIHAFCEYDGGVERRWLSSFMDRQRNQRIHSPLDRAGRVAHCLEPMLGCLCNFFLTEEGQETYKFLDAWMDAMDNRFTSRVMVECSIVEALARQICKNNPTIGISEQPKEVLSAVDRLKDQLHAMDYSASTKERLTSLLGMVRNRSAKDRLFAIQRAGWGGVSVDEISSWSALRNKVMHGDSPIGDGSLPRFQNAVTHSAKIANLINRMVLQSAGYSGSFFDYSTWMPAELPAGDIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ILX3</accession>
    <name>A0A518ILX3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TadE-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_00180</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012495">
        <property type="entry name" value="TadE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07811">
        <property type="entry name" value="TadE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="154" mass="16860" checksum="156D7F10394EEA43" modified="2019-10-16" version="1">MRFPNRTQTKPADLQSSRCRSPRHAVAAIELAIALPMLMLFTLACADLGRVIHLKVALSNATRVAAEYGAMRKVTSINRDEWTAGIQQAFASDLQATAAFADIETTVQADTEEGELGLYRVRVESQCEFVPAVDWPGLPSSIDLQASVVMLQLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ILY0</accession>
    <name>A0A518ILY0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_00490</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="181"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="223"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="345"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="373"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="398"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="424" mass="46110" checksum="F5CDF0A09D5427F0" modified="2019-10-16" version="1">MSSVSLPIEPSRPNGVAKFAAIVWQPSLVFVPFLVVGAVLWLCPSMEGAAGYGIREEVSLANLTILVAWYGTICAAAAIGQRLAMALPRFNVMSKDAFDPTVFYKTLACLALIGVAGAWVAALRNGVSLIELVKTQQFNLVKDSLYANYNHLYSLRYTASLVGGYALYRLVFLQKVSRLDILSLCLLLAATAISARILIAQAVIFAGGLAIRFDALQRVKTRTITAAVLGLAICIVAFTWVRSAGSYRDHFGVENPVAMTFLEVQRYVGAPVQASMGVARMAADQPSRGAIGNIIKYTTPTFLHPAELKVEDNSGGVAAQWYLHQVDIDETLTTNSAFVEMFGDLGFWAFPVMAWASFLMATIGSYFWRSDNLLCLIGCVVLYGFFELWRTYYFSAGSFTFMILAVLVAATTASLLKPTPRTAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IM36</accession>
    <name>A0A518IM36_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_01040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="252"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="252"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="283" mass="31121" checksum="37B1EE8F7C0278D5" modified="2019-10-16" version="1">MESSQSRPTRATRQPDLAVKTFLDYSPMKKFLFILIFAACPIATGCATAPKSESWSAKLPWNKDKPPKPYPNPVKMAVTWTPDILVQPGRTPTRGFGGRVYFYNDHSQAVPVEGELTIHGFDEALASAQHSDGIKRFRFTKEQFTSHFSESDLGASYSIWIPWDAAGGDQKKLSLMSTFKTTGGKVVQSEAAMVVLPGRKVDMTATKRPAVPAVRQVGHYLGTTETHQGLNANSAMQTTTIPLPSSFQQRLARMPEQTKPSKRMTTRLPAAQETSKPTPLPAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMM4</accession>
    <name>A0A518IMM4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Enolase</fullName>
            <ecNumber evidence="8">4.2.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">2-phospho-D-glycerate hydro-lyase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">2-phosphoglycerate dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 13" type="primary">eno</name>
        <name evidence="13" type="ORF">Mal33_02740</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>(2R)-2-phosphoglycerate = H2O + phosphoenolpyruvate</text>
            <dbReference type="Rhea" id="RHEA:10164"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58289"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="4.2.1.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="8">The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 4/5.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Secreted</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Cell surface</location>
        </subcellularLocation>
        <text evidence="8">Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the enolase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.11" evidence="8"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00187"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000015">
        <property type="term" value="C:phosphopyruvate hydratase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004634">
        <property type="term" value="F:phosphopyruvate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03313">
        <property type="entry name" value="enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00318">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000941">
        <property type="entry name" value="Enolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036849">
        <property type="entry name" value="Enolase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029017">
        <property type="entry name" value="Enolase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020810">
        <property type="entry name" value="Enolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020809">
        <property type="entry name" value="Enolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020811">
        <property type="entry name" value="Enolase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11902">
        <property type="entry name" value="PTHR11902"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00113">
        <property type="entry name" value="Enolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03952">
        <property type="entry name" value="Enolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001400">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00148">
        <property type="entry name" value="ENOLASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00002">
        <property type="entry name" value="enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01192">
        <property type="entry name" value="Enolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01193">
        <property type="entry name" value="Enolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51604">
        <property type="entry name" value="SSF51604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54826">
        <property type="entry name" value="SSF54826"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01060">
        <property type="entry name" value="eno"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00164">
        <property type="entry name" value="ENOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="7 8 13" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Enolase_N" evidence="12">
        <location>
            <begin position="4"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="Enolase_C" evidence="11">
        <location>
            <begin position="139"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8 10">
        <location>
            <begin position="364"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8 9">
        <location>
            <position position="205"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8 9">
        <location>
            <position position="337"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="155"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="242"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="285"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="312"/>
        </location>
    </feature>
    <feature type="binding site" description="covalent; in inhibited form" evidence="8">
        <location>
            <position position="337"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="388"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR001400-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR001400-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM01192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="QDV54323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="425" mass="45569" checksum="1BFB02EDE8081839" modified="2019-10-16" version="1">MSLIENVHARQIMDSRGNPTIECEVTLMDGSFGRAAVPSGASTGVHEAWELRDGDKSVYMGKGVLKAVANVNDKIAAVLAGMDAIDQRAVDSRMCELDGTANKSELGANAILGVSLATARAAAQFTQQPLYRYLGGVNASILPAPMMNILNGGSHADNSVDIQEFMVMPLGFNSFSDGLRAGTEIFHSLKKVLSSKGLNTSVGDEGGFAPNLGSNREALDLIMQAIDNAGYKAGEQIFIALDAASTEFYDGDSKKYKIDGKELSGSEMVDFMADWCANYPICSIEDGCAEDDWDSWKLMTEKLGDKVQLVGDDLFVTNTERLQRGIDEGIANSILIKVNQIGTLTETIEAIQLASRAKYTSISSHRSGETEDSTIADLAVALSTGQIKTGSASRSDRMAKYNQLLRIEEELGSEAQYGGPLFPTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMR2</accession>
    <name>A0A518IMR2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_03320</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006842">
        <property type="entry name" value="Transposase_31"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04754">
        <property type="entry name" value="Transposase_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transposase_31" evidence="1">
        <location>
            <begin position="8"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="313" mass="35209" checksum="95D550ECD128CCCE" modified="2019-10-16" version="1">MSDDAVNNPHDRFVRRFLGEIDQVRQLVLWRLPPEVVAELDLDTIAPAKQSFVDQTLRESLSDLVFEVALAGGGEALVVLLFEHKSTPDAMTSFQVLRYIVGVLDQRQRDSLPLCCVIPIVLYHGVRPWNVARSLPELIAAPASLQPYVPSFTMPLIDLSCCTDEELRTESLFFAYMSLLKYIGRDELPERLPELLRLFRKLLPPATGLSSLETILRYLVSGTDRVTRDQLRTAVADALRIEGESLMPTIAEQWLKEGVEKGIEKGEWIGRIRTLQEVLSRKVDSVESLMSLQVSELQQLAGDLSEALPKEGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMU1</accession>
    <name>A0A518IMU1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_03630</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="139" mass="15501" checksum="EC8AE72402E789FD" modified="2019-10-16" version="1">MRTLASVSIGTLVRLWAFPYTLLGVVVGLGLLGRPKLVGGVIEIYGPGVAWVLQRLPVSALAITLGHSVLGQTQAALDLTRRHERVHVRQFERWGFLMGLAYLGASGWLWWRGKDAYRDNPFEIEAYAVDDCRRNPGRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IN32</accession>
    <name>A0A518IN32_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Arylsulfatase</fullName>
            <ecNumber evidence="6">3.1.6.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Mal33_04380</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="PTM">
        <text evidence="1">The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.</text>
    </comment>
    <dbReference type="EC" id="3.1.6.1" evidence="6"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004065">
        <property type="term" value="F:arylsulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032506">
        <property type="entry name" value="DUF4976"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16347">
        <property type="entry name" value="DUF4976"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021950197" evidence="3">
        <location>
            <begin position="25"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase" evidence="4">
        <location>
            <begin position="33"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4976" evidence="5">
        <location>
            <begin position="379"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="446"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="448"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="modified residue" description="3-oxoalanine (Cys)" evidence="1">
        <location>
            <position position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR600917-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF16347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV54484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="472" mass="52295" checksum="04B39FCA82FC1022" modified="2019-10-16" version="1" precursor="true">MGYAQRVRRIGLVAALLFAGTGFAKAIAAEQQPNFLVIVSDDQRPDTIAALGNSVIETPNLDQLVREGMTFTRASSAFPLCVPSRAEILTGATAFHNGVPYGGGRLKKGQVFWADALRNAGYQTWYCGKWMNDGAPKTRGYEETSGLFSSGGAGPLGREPRYGRHNRLITGYRGWTFKSADGTPELEKGIGVVGETSKYIADGAIELLQRKTDKPFFMHVNFTAPHDPLIIPPGYAGKYKPSEMQVPANLLPKHPFDHGNIDGRDEQLLPWPRTEADVREEIAAYYAVIDDMDAQIGRILAAMKASGRYDNTVILFTSDHGLALGSHGLMGKQNMYEHTIGVPFIIAGPGIPKNQRTAAQIYLRDMYPTTCELAGIPIPETVESKSIVPILRSPDAEIYPAVFGYYKDTQRMIRTSRWKLIRYPKVGRTQLFDLENDPDELVDLSGSSKHQELASRLGDQMDQWFQQQNEKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INL9</accession>
    <name>A0A518INL9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">Trigger factor</fullName>
            <shortName evidence="9">TF</shortName>
            <ecNumber evidence="3 9">5.2.1.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 9">PPIase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9 13" type="primary">tig</name>
        <name evidence="13" type="ORF">Mal33_06450</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="9">About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.</text>
    </comment>
    <comment type="domain">
        <text evidence="9">Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the FKBP-type PPIase family. Tig subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="3 9"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1050">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00303">
        <property type="entry name" value="Trigger_factor_Tig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005215">
        <property type="entry name" value="Trig_fac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008880">
        <property type="entry name" value="Trigger_fac_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037041">
        <property type="entry name" value="Trigger_fac_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008881">
        <property type="entry name" value="Trigger_fac_ribosome-bd_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036611">
        <property type="entry name" value="Trigger_fac_ribosome-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027304">
        <property type="entry name" value="Trigger_fact/SurA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30560">
        <property type="entry name" value="PTHR30560"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05698">
        <property type="entry name" value="Trigger_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05697">
        <property type="entry name" value="Trigger_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003095">
        <property type="entry name" value="Trigger_factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102735">
        <property type="entry name" value="SSF102735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109998">
        <property type="entry name" value="SSF109998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00115">
        <property type="entry name" value="tig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="9" id="KW-0132">Cell division</keyword>
    <keyword evidence="6 9" id="KW-0143">Chaperone</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 9 13" id="KW-0413">Isomerase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="Trigger_N" evidence="11">
        <location>
            <begin position="22"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="domain" description="Trigger_C" evidence="12">
        <location>
            <begin position="286"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="442"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="444"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00029986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF05697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF05698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="QDV54689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="497" mass="56324" checksum="D1AEEE1572EAA1C1" modified="2019-10-16" version="1">MSTTDAPSSSENTEATKLTLTVEVDAPQTCLRHVVVTVSRGDVERYLKNAYDELAPEASVPGFRAGRAPRKLVEKQFKERVADQVKGQLLMDSLGQVTEEQAFSAISEPDFDFESVELPESGDFRFEFKVEVRPEFDTPQWKGLSLTEPDEQVDDEAIDASVARVMSRYSKYEAVDDAAKMGDRLLVTATFRNEGEVLSEMEEERVELVSGLSFPDGRCEEFGKLMEGVREGETRTGKVTVSQEAHPELGGKEIEAEFNVIEVSRNEVAELTPAVLEELGDFETEEELRKFIAESLQRQIDYRRQRSLRSQITKTLTEDANWELPPDLVRRQTRRELERQILEMRRSGFQEEDIRNMVNMARQNAQAQTEAALREHFILEKIADDQDIDAAPSDYDDEIALIAEQSDQPERRVRARLEKSGQMDALRNQIVERKVIEMITADATVTKEKAEKKEDGSGNDRDFAVDHSLVRAKEELPEAKYDDSNKGEASETPTNKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INP5</accession>
    <name>A0A518INP5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Low molecular weight protein-tyrosine-phosphatase YfkJ</fullName>
            <ecNumber evidence="4">3.1.3.48</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">yfkJ</name>
        <name evidence="4" type="ORF">Mal33_06680</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the low molecular weight phosphotyrosine protein phosphatase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.48" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006470">
        <property type="term" value="P:protein dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023485">
        <property type="entry name" value="Ptyr_pPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036196">
        <property type="entry name" value="Ptyr_pPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017867">
        <property type="entry name" value="Tyr_phospatase_low_mol_wt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01451">
        <property type="entry name" value="LMWPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00719">
        <property type="entry name" value="LMWPTPASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00226">
        <property type="entry name" value="LMWPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52788">
        <property type="entry name" value="SSF52788"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LMWPc" evidence="3">
        <location>
            <begin position="2"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV54711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="147" mass="15809" checksum="E0A1E542C961B213" modified="2019-10-16" version="1">MGNICRSPAAEGVMRRLVEAEGMDDRITIDSAGTIGFHTGKAADRRMRAAAQQRGLELTSRARQVTAADLQAFDLVVAMDADNARDLNALADGGSANIVLLSSFLEDDWPSDVPDPYYGGDEGFEFVLEMLDAACPKILESLKSNTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INT2</accession>
    <name>A0A518INT2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_07140</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011453">
        <property type="entry name" value="DUF1559"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07596">
        <property type="entry name" value="SBP_bac_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="39"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="370" mass="39892" checksum="D912CD645FBEA597" modified="2019-10-16" version="1">MTNRSEGEVWEQSCVGRRRGFCPAPRCCRLAGGSSRRAFTLVELLVVIAVIGVLVGLLLPAVQSVREAARRMQCSNNLKQLGLAAHNYHDTHRSFPSGWINPKPWDADRDCYGWGALILPFVEGTAAANAIDAVRVPFNAALNDSEKLRVMRQKQEVFRCPSDVGPIESSDGDRKPGGESTAVSNYVGANNIGWAEASDSGAAGDGGPGRHGMFVEDKGIRFRDVRDGTSAVVLFGERRWQYNDVLDRTVQVAAAALVYGRETNGSLSAEASAVIGLGIVRMNYDGAKSGDTGARRKKTGFSSLHPGGAMFAFVDGSVHFVADGIEFTVKLETDPTSLHYLVNNNEGNGPPDDVYERLIARDDGQVLGQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INV0</accession>
    <name>A0A518INV0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF1080 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_07340</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010496">
        <property type="entry name" value="3-keto-disaccharide_hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06439">
        <property type="entry name" value="DUF1080"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022230949" description="DUF1080 domain-containing protein" evidence="1">
        <location>
            <begin position="26"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1080" evidence="2">
        <location>
            <begin position="28"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="225" mass="24733" checksum="E80C36698C357FB2" modified="2019-10-16" version="1" precursor="true">MRKLFTSAFLLMLAACSVAPSTATADDGWVSLFDGKSLAGWTQKNGTATYAVEDGTIVGRTAVGSPNSFLCTDKDYGNFELEFEVKVDKGLNSGVQIRSQTKEQENNKKGYGRVNGPQVEIESGPAEAGYVYGEATGRGWLTPAERLKPHDHFDNDGWNKYRIVANGPRIQTWINGEMIEDLTDEPIFETHSNGFIGLQVHGIGKDKGPYQVAWRNIRIKELAGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP03</accession>
    <name>A0A518IP03_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_07570</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010869">
        <property type="entry name" value="DUF1501"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07394">
        <property type="entry name" value="DUF1501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="486" mass="53216" checksum="2D6D8C6420DB9E9F" modified="2019-10-16" version="1">MTTNNEFCRRTRRQALWEMGCGFTGTALATMLGDSFLGTQTVAADGKTAWENPLAPKQPPLPAKAKSVIFLYMYGGPSHIDTFDYKPAMKGMDNKSIEVKTFGRGGHKNKGRIVEPRWDFKQYGECGKWVSDLFPNLGTCVDDIAFIHSMTADSPIHGSAMLQMNSGRILSGSPCLGSWVNYGLGTVNQNLPGFVVMLDPRGGPISGAKNWSSGFMPAHYQATVMKSNGSPILNLKPQAGMTDALQRDLLDTMRKYNEQHQAARIENTDLAARISSYELAYQMQAAAPDAVDLSKEDARTIDDYGMNDEKSKTFGKQCLMARRLVERGVRCVQIYSGGAHNDDNWDAHNDIAVNHNLHAAETDKPIAALLKDLKQRGMLDSTLVVWGGEFGRQPTAEYEKGTGRDHNAYGFTMWMAGGGIKGGVSVGKTDELGAAAVENRYHVKNLHATILDRLGFDPNHLTYFFGGLDQKLVGVEGAEPIHQVLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPB8</accession>
    <name>A0A518IPB8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_08800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="163" mass="18392" checksum="B4431A64F257299B" modified="2019-10-16" version="1">MIAQNTFAHSPNSPANASVVQYDRLPLERFPLPKPNPAKAKLPELRHLAERILYARDAWEEEAAEHVAFEIRAAHCQIRERRTTKASRPLAIAIYVLHVTVDVQSDGTSQDVLDACDGFITDLRSLFHLRCEPQVRDAESVLGYLGADSYEDAWDAIGEFYWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPB9</accession>
    <name>A0A518IPB9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_08780</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="139" mass="15821" checksum="1D23D7E7B06E7342" modified="2019-10-16" version="1">MAKATEAWTEVLKLDSSDKEAREFFRTIGRLDVVQKQIARAKSTENARDLGAVSHWAMKHSWGFLDSRKQEMATLRLLANGRVKASAKYPDAHWMPLDENAILFNYNPGGSYIVFHKETDSLFVGKNSMSGSPRYLQRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPK5</accession>
    <name>A0A518IPK5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Outer membrane protein assembly factor BamB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">bamB_1</name>
        <name evidence="2" type="ORF">Mal33_09910</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018391">
        <property type="entry name" value="PQQ_beta_propeller_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002372">
        <property type="entry name" value="PQQ_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13360">
        <property type="entry name" value="PQQ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00564">
        <property type="entry name" value="PQQ"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022139582" evidence="1">
        <location>
            <begin position="22"/>
            <end position="759"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="759" mass="82150" checksum="EA84E67047BA859E" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPQ9</accession>
    <name>A0A518IPQ9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ribonuclease R</fullName>
            <shortName evidence="5">RNase R</shortName>
            <ecNumber evidence="5">3.1.13.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 8" type="primary">rnr</name>
        <name evidence="8" type="ORF">Mal33_10540</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates.</text>
            <dbReference type="EC" id="3.1.13.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the RNR ribonuclease family. RNase R subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.13.1" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008859">
        <property type="term" value="F:exoribonuclease II activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01895">
        <property type="entry name" value="RNase_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040476">
        <property type="entry name" value="CSD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013223">
        <property type="entry name" value="RNase_B_OB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001900">
        <property type="entry name" value="RNase_II/R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004476">
        <property type="entry name" value="RNase_II/RNase_R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011805">
        <property type="entry name" value="RNase_R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17876">
        <property type="entry name" value="CSD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08206">
        <property type="entry name" value="OB_RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00773">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="3"/>
    </dbReference>
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        <property type="entry name" value="3_prime_RNase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="4 5" id="KW-0269">Exonuclease</keyword>
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    <keyword evidence="5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
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        <location>
            <begin position="610"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="694"/>
            <end position="729"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV55085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="729" mass="82755" checksum="B09286512C8549F1" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPV2</accession>
    <name>A0A518IPV2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
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            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="81" mass="9020" checksum="B0A814F81C1C19FF" modified="2019-10-16" version="1">MEPSEQLDLTSDPNGSASRGGDSKAKPFLGVVFSCCNIYVRVYRDRKGGAFYEGRCPQCFAKIRFVEGNGGRRDTFFRTQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPW8</accession>
    <name>A0A518IPW8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF1801 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_10790</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Rosistilla</taxon>
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    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014922">
        <property type="entry name" value="DUF1801"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08818">
        <property type="entry name" value="DUF1801"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1801" evidence="1">
        <location>
            <begin position="29"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="136" mass="15221" checksum="78878E3E24EC986E" modified="2019-10-16" version="1">MAENKTQPTDASVDDFIAAIDNSRRRADALTALAIYKEITRLPAVMWGPSIIGFGTYHYVYATGREGDMPAAAFSPRKSNMTFYVSDTFDGADSLFQRLGKHKRSVACLYINKLDDVDLEVLREIIARQYTHGYAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPZ3</accession>
    <name>A0A518IPZ3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ribosomal RNA small subunit methyltransferase D</fullName>
            <ecNumber evidence="3">2.1.1.171</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rsmD</name>
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        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.1.1.171" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052913">
        <property type="term" value="F:16S rRNA (guanine(966)-N(2))-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004398">
        <property type="entry name" value="RNA_MeTrfase_RsmD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004553">
        <property type="entry name" value="CHP00095"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="186" mass="20888" checksum="77D6CAC6470B7D1B" modified="2019-10-16" version="1">MRGRKVRYNGDRSTRPMRDSVRESLFNLIGQRIKGSIVFDPFGGTGVLAIESISRGASRAVTMEQNRRTLEQIRQNVADLDLTDRISLTAGDAFRGLGALMHQAHAEEPDTPWVFLMCPPYEMFQSRIKDLNRMICFAAEAHPHGVLVAECDNFFDTAELTAAEWDVRKYGITQLALTELSSVQLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQ02</accession>
    <name>A0A518IQ02_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_11260</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="72" mass="8377" checksum="B7E415BC31F02528" modified="2019-10-16" version="1">MSDLPDRELRPTMRLRFLVKGSHRSLQQEHQVWVRGYENDGFDGGQSWPAMVPSSETEWVNVESVIEFAEID</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQ03</accession>
    <name>A0A518IQ03_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_11410</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="359"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="929" mass="102751" checksum="68D2AD156BAFD30C" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQ85</accession>
    <name>A0A518IQ85_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SsrA-binding protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Small protein B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 5" type="primary">smpB</name>
        <name evidence="5" type="ORF">Mal33_12170</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="3">The tmRNA-SmpB complex associates with stalled 70S ribosomes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SmpB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070929">
        <property type="term" value="P:trans-translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09294">
        <property type="entry name" value="SmpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00023">
        <property type="entry name" value="SmpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023620">
        <property type="entry name" value="SmpB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000037">
        <property type="entry name" value="SsrA-bd_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020081">
        <property type="entry name" value="SsrA-bd_prot_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30308">
        <property type="entry name" value="PTHR30308"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01668">
        <property type="entry name" value="SmpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74982">
        <property type="entry name" value="SSF74982"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00086">
        <property type="entry name" value="smpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01317">
        <property type="entry name" value="SSRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV55247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="167" mass="18993" checksum="580EC7FDE0942690" modified="2019-10-16" version="1">MAKKKQQKSKAKSGKKPPPPKNVAENRKAKHQYEIFETLECGMVLVGSEVKSMRDGKLSLDEAYGRIQGGELWLIGADIGHYSNAGLWNHDPRRPRKLLVHSRELDKVSGKAKERGVTIVPLRVYFNERGIAKCVIGLVRGKKLHDKRETLKKRDTDRGLARAMRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQE7</accession>
    <name>A0A518IQE7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ABC1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ubiB_1</name>
        <name evidence="3" type="ORF">Mal33_12870</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004147">
        <property type="entry name" value="ABC1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03109">
        <property type="entry name" value="ABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="530"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="domain" description="ABC1" evidence="2">
        <location>
            <begin position="97"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="564" mass="63628" checksum="8E965D19D4479D22" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQH7</accession>
    <name>A0A518IQH7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ribonucleotide monophosphatase NagD</fullName>
            <ecNumber evidence="3">3.1.3.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">nagD</name>
        <name evidence="3" type="ORF">Mal33_13050</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HAD-like hydrolase superfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.5" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106411">
        <property type="term" value="F:XMP 5'-nucleosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006357">
        <property type="entry name" value="HAD-SF_hydro_IIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13344">
        <property type="entry name" value="Hydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000915">
        <property type="entry name" value="PGP-type_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01460">
        <property type="entry name" value="HAD-SF-IIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="9"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR000915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000915-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="286" mass="30657" checksum="3DE5C4829F387FDC" modified="2019-10-16" version="1">MSKLGFLIDMDGVIYKGNQLIRGADRFIARLHQNDHPFLFLTNNSQRTQRDVAVRLQRMGIEAREEQIFTCAMATASFLSKQKPNGTAYVIGEGGLLQALHLNGYSIVDTDPDYVVVGEGRTVTAEALDAATRMILAGAKLIATNLDPNCPTASGTRPGCGATVAFLEMATGKKASSMGKPSPVMMRAARKQLGLTTSQTVMIGDTMETDIIGGVQMGYHTVLALSGGTQLTDLDNYAFGPDLVVESVEELADPSCCLETLFGLSDDEPASTESVANHRQLQLAHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQI1</accession>
    <name>A0A518IQI1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Flagellar basal body protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">flgG_1</name>
        <name evidence="5" type="ORF">Mal33_12910</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Bacterial flagellum basal body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the flagella basal body rod proteins family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009425">
        <property type="term" value="C:bacterial-type flagellum basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001444">
        <property type="entry name" value="Flag_bb_rod_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020013">
        <property type="entry name" value="Flagellar_FlgE/F/G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010930">
        <property type="entry name" value="Flg_bb/hook_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037925">
        <property type="entry name" value="FlgE/F/G-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00460">
        <property type="entry name" value="Flg_bb_rod"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06429">
        <property type="entry name" value="Flg_bbr_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117143">
        <property type="entry name" value="SSF117143"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03506">
        <property type="entry name" value="FlgEFG_subfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="5" id="KW-0966">Cell projection</keyword>
    <keyword evidence="5" id="KW-0969">Cilium</keyword>
    <keyword evidence="5" id="KW-0282">Flagellum</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flg_bb_rod" evidence="3">
        <location>
            <begin position="5"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="domain" description="Flg_bbr_C" evidence="4">
        <location>
            <begin position="175"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV55320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="250" mass="26990" checksum="5BF602781F31C423" modified="2019-10-16" version="1">MPYGMYMSAAGAKAQSHRLEVVSHNLANVNTPGYKAQAPVLQARFAESIEESLKNPGTGEVDDVGGGVTLQSTGTEFREGPIKQTGVRTDFAIHNASDFFVVQHDDQQMLTRAGNFLFNSNGTLVNQGGDPVLDTGGRPIQIDPRLPFDVTAGGRITQSGTTFDLMLARPNGYGDLSRQGENLYMPLAEFQPVAPTEREVANGALEQSAVNPTTTMMELIEASRGYEANTKMIQNQDHVMGSLISRILQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQK3</accession>
    <name>A0A518IQK3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cation efflux system protein CusA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">cusA_1</name>
        <name evidence="2" type="ORF">Mal33_13400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2090.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82714">
        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="422"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
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            <end position="466"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
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            <end position="495"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
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            <end position="539"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="560"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="594"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="668"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="706"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1126"/>
            <end position="1145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1152"/>
            <end position="1173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1193"/>
            <end position="1213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1253"/>
            <end position="1270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1282"/>
            <end position="1304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1325" mass="145563" checksum="1DDBF3919C51D3DE" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQP6</accession>
    <name>A0A518IQP6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_13900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
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            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="61"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="80" mass="8594" checksum="2134162A38A99984" modified="2019-10-16" version="1">MRNIDPNATSDETVQFIVELANGQTIRAHAGPSGLPVILCDDLPADLPAFTERCPPTAGQFAPHWDSGVDESHRLQKAGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IR21</accession>
    <name>A0A518IR21_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">4Fe-4S binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_14970</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="2">
        <location>
            <begin position="218"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="2">
        <location>
            <begin position="248"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="339"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="364" mass="39507" checksum="7CAC169C36394A54" modified="2019-10-16" version="1">MSNPLTVVISQGQSRNPQKRGLEQSVAQRAAEIDGVSVLLIPHLYDLAAAGESLATMRSIPGDMVVLSWVYERAAHWILDRGGVRGQFGEVALVRDEEDDDQEEQPEDSQIEEKERVAEHAPRPNRIIYSLDFRVTEAADPIVAELQRIAALPRTAGESAAARFEQPTNTTSLRLAGDADANDQALEEVPETNGRPAEPALFGIGAVTKIDESPSRRWYPVIDFSRCTNCMECIDFCLFGVYGVDTVETILVEQPDNCRKGCPACSRVCPENAIIFPQHKSPGIAGAPVEAGGLKIDLSKLFGAPDADEDPIATAARERDEQLLLAGRATVGLEVGIPKRQSAASDQPKDDLDNLLDELDGLDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IR38</accession>
    <name>A0A518IR38_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosome-binding ATPase YchF</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 7" type="primary">ychF</name>
        <name evidence="7" type="ORF">Mal33_15350</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043023">
        <property type="term" value="F:ribosomal large subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04867">
        <property type="entry name" value="TGS_YchF_OLA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01900">
        <property type="entry name" value="YchF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00944">
        <property type="entry name" value="YchF_OLA1_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004396">
        <property type="entry name" value="ATPase_YchF/OLA1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004095">
        <property type="entry name" value="TGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012676">
        <property type="entry name" value="TGS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023192">
        <property type="entry name" value="TGS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013029">
        <property type="entry name" value="YchF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041706">
        <property type="entry name" value="YchF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06071">
        <property type="entry name" value="YchF-GTPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006641">
        <property type="entry name" value="CHP00092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81271">
        <property type="entry name" value="SSF81271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00092">
        <property type="entry name" value="TIGR00092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51880">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OBG-type G" evidence="5">
        <location>
            <begin position="1"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="domain" description="TGS" evidence="6">
        <location>
            <begin position="278"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="10"/>
            <end position="15"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV55558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="363" mass="39341" checksum="2366FF46CE79A46F" modified="2019-10-16" version="1">MEAGIVGLPNVGKSTLFNALTSSQAAQSENYPFCTIEPNEGIVNVPDGRLQTITDLIHTKKIIPAALKLVDIAGIVKGASEGEGLGNKFLSHIRQVDAIIQVVRCFEDPDVTHVAGNVDPMADIDTIETELILADIQTLENALPKAERTARTGDKEAKLLVATINKHLEHITKELPLRTLSLTEAEAKVVSSFGLMTAKPILYVANVDENDVNGENDLVAKVREHAKHSGAGVVPVCAKVEAEVAELEPEDRAEFLDAVGLTEPALEKLAREAYRTLGLHSYFTAGEKEVRAWTIPVGATAPQAAGVIHSDFERGFIRAEVYSVEDLVEHKSEKEIRNAGKLRVEGKGYVMNDGDVVHFLFNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IR51</accession>
    <name>A0A518IR51_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Undecaprenyl-phosphate mannosyltransferase</fullName>
            <ecNumber evidence="3">2.4.1.54</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_15450</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.4.1.54" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004582">
        <property type="term" value="F:dolichyl-phosphate beta-D-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047267">
        <property type="term" value="F:undecaprenyl-phosphate mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039528">
        <property type="entry name" value="DPM1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43398">
        <property type="entry name" value="PTHR43398"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="2">
        <location>
            <begin position="32"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="273" mass="30173" checksum="4BE7C35E127E23CB" modified="2019-10-16" version="1">MNLQSDPQSLLAEQRQRNPLSPPSYPKSKVYVVLPAFNEEQALGALLNNLGEAFADSGWPYEVIVVDDGSVDATAELAGQYGFQMPVHLLKHSENMGLGPTLRDGLREAAELATARDVILTMDADNTHPAGLIDSMVRRIKEGSDIVIASRFRDGAQVVGVPWNRLFLSVGARMLFSLIFPTKGVRDYTSGYRAYRAEAIQEGFAHFGDNLVSETGFSCMADVLLKLRSRKRVFSEVPLILRYDQKGGVSKMKVMRTAILTLKLLARHRFTGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IR80</accession>
    <name>A0A518IR80_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Inositol 2-dehydrogenase</fullName>
            <ecNumber evidence="4">1.1.1.18</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">iolG_4</name>
        <name evidence="4" type="ORF">Mal33_15750</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.1.18" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050112">
        <property type="term" value="F:inositol 2-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004104">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02894">
        <property type="entry name" value="GFO_IDH_MocA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GFO_IDH_MocA" evidence="2">
        <location>
            <begin position="54"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="GFO_IDH_MocA_C" evidence="3">
        <location>
            <begin position="204"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV55598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="444" mass="48838" checksum="530FBD0CEB326018" modified="2019-10-16" version="1">MPIEDASDHSTVQPAKSHTDRRNFLCSTAAASTFAAMTVPSMVHSEEATKKQTINLGIVGCGGRGSGAINDSLSINEGIKLVAAADLYADKNERLKSTLTRRHPEKIALEENKMYTGLDGYKKVLEDPDVDVVLLTTSPGFRPYHILEAVEAGKHVFAEKPSCVDPAGYQICLKAHELAEKNGTSIVTGTQYRRQVNYVGAVDKIRSGMIGDIVSATSRYCSTGIWYKNRTEGMSDTEYQLNNWMHFIWLSGDQITEQAVHNIDTMNWVMGSAPISAYGSGGRFTRPDDSEMWDNMEIDYMYPGDRNLSFMCRQVPGTRGDNSNVIYGTEANCHIGAGSTGSRIVDRNGKELWSMKGSIADAYKQEHKDLIDAVRSNQPIVELKQTAESSLTAVMGRMAAYTGQLVSWDFASKESTLDLFPKELAWDGKRPAGEYAIPGKTKLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRF4</accession>
    <name>A0A518IRF4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Beta_helix domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_16000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039448">
        <property type="entry name" value="Beta_helix"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006626">
        <property type="entry name" value="PbH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13229">
        <property type="entry name" value="Beta_helix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00710">
        <property type="entry name" value="PbH1"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta_helix" evidence="1">
        <location>
            <begin position="340"/>
            <end position="554"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="875" mass="97446" checksum="ADCA4B4B4D89426A" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRR8</accession>
    <name>A0A518IRR8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_17590</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="459" mass="50820" checksum="9E639B217119EA78" modified="2019-10-16" version="1" precursor="true">MTINSTRLSPKSWLPRWNPVGLLLLIVIAICSIAAGQESTDTDADDRQARVEVDRLVSGLDGRTLAERQAAERDLIDLGPQILKFLPRENDLPTAEMRQRMRRIRSQLEHLESTTSIDAMPVTIRDARTLGDALGQISAQTKVQFAGAIKESLPVKIDAVKIPFWNAVDEVLDAAELDIDRFGGVEGSLKLVPRGPDRPRRSDTAAYSGVFRVEPISVTARRDLHNPRLSGLDLLIDISWELRLTPIGLSLPLKEFGAKLDNGDVLQLQASAETAEAMPNAGIPSTQTLIPFQLPAGRPAKIDTLSGTIDALLPGKIKHFDFDLGDDNFPPRDAGDVTVTLESVRGNGSLHELRVNVKFKQADRALESHRGWVFDNPAYVTAANTDQDETREDAAAEQAQPTRIENLGYEIYRQTSDEIGIGYLFDLEGQPDRFRFHYETPASIVRSEVRFTLHDILLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRU0</accession>
    <name>A0A518IRU0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DAC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Mal33_17730</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2 ATP = 3',3'-c-di-AMP + 2 diphosphate</text>
            <dbReference type="Rhea" id="RHEA:35655"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:71500"/>
            <dbReference type="EC" id="2.7.7.85"/>
        </reaction>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106408">
        <property type="term" value="F:diadenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036888">
        <property type="entry name" value="DNA_integrity_DisA_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003390">
        <property type="entry name" value="DNA_integrity_scan_DisA_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02457">
        <property type="entry name" value="DAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143597">
        <property type="entry name" value="SSF143597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DAC" evidence="6">
        <location>
            <begin position="348"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV55794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="424" mass="47289" checksum="D5DE0C4B6658E2D8" modified="2019-10-16" version="1">MTSLASYPAEIAAALQRRWTAMELPADALPAADAVAQLVDTMYQASLLREEGSGVRCRIIVAPPSEFAAELSTGASQLHVLRFTERRDFTPHQLRKLAAAAGYYRALLAVDQNADGQLSIWGMVITGTDWVNRVEGERVRELWLPTRPVIHCVGPGHLIAAAGHSRILESSGGKLLTDGFDPFRSSWLSHQFRQVRTSLIEELAELETDSSKTRMCDSFVKDIAQSVVRRVLHLVRTRGHGGMLVFLPNGLESNPLVDRWFRFRVRFEGDDSTLRFRRLILNLMQQGRKAGEARGLDQVTWDDYLQMRHAELAQLDAALLEFGHFLADLMSADGSLVVDRSFRLVGFGAEILGDSHVNTIHRAFDLEAINAVPEPADSSGTRHRSAYRLVSGLREAIAVVVSQDGDVRFVAHHKDKLTYWPYLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRU4</accession>
    <name>A0A518IRU4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_17970</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008323">
        <property type="entry name" value="UCP033563"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36454">
        <property type="entry name" value="PTHR36454"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06245">
        <property type="entry name" value="DUF1015"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF033563">
        <property type="entry name" value="UCP033563"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="409" mass="45618" checksum="AAF179B4A4D43D56" modified="2019-10-16" version="1">MPRIKAFRALRPQADNAAKVASVPYDVCDRDEAVELAAGNPDSFLHIVRPDIDLPADTNPYDDAIYAKASDNLQRFLRDNVLQQDDGDAIFLYRQVMNGNSQVGVVCCCHVEDYENNLILKHEKTRKAKEDDRTRHVLTLGAHTGPVFLTYRDDSKTNAMVETAITEAPLYDFTAADGVQHTVWKIDNAADYVSALSAVPKFYVADGHHRAASAWRAGAERRDNNPDHTGDEEYNWFLTVLFPASQLNILSYNRVIKDLNGQSVEQVREKLAQLGTFEPITDPVPPTAGSFCFYLGGSWYRLTLPADSIDHNHPIDSLDVALLEKRVLQPIFGIEDVRTDPRIDFVGGIRGTKALETRVDSGAWACAISMYPTSIEQLMGVSDADEIMPPKSTWFEPKLRSGLLVHLLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRX5</accession>
    <name>A0A518IRX5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_18110</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="264" mass="29185" checksum="12D1C5F3A1D58533" modified="2019-10-16" version="1">MRTYGYLVVEGPHDIEFAYRLLAPYGLERVRLEAELDPFFQPLVPTTFPHNGDLQARVPVPLFMQSNSHAIALHSALGDTRLAQTIEESAFSIDYSQLAGIGIILDTDKEVAVTTRYAGLKEEFARNSFNLPAIPGTISADEQRVGVFVLPDNQSEGNLEDLLLQCAESTFPKLLESARKHVDFARDDTSFVDKKREDLSKSAKYNKAVVGSIATTLRPGRAVQASIQDNVWLRGNNLNLPRIKAVQTFLVDLFGLALPTAPTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IS42</accession>
    <name>A0A518IS42_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">BNR/Asp-box repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_18970</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004308">
        <property type="term" value="F:exo-alpha-sialidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011040">
        <property type="entry name" value="Sialidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026856">
        <property type="entry name" value="Sialidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036278">
        <property type="entry name" value="Sialidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10628">
        <property type="entry name" value="PTHR10628"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13088">
        <property type="entry name" value="BNR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50939">
        <property type="entry name" value="SSF50939"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sialidase" evidence="1">
        <location>
            <begin position="175"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="392" mass="42927" checksum="F1E9963000A6C6F8" modified="2019-10-16" version="1">MMDPISRRSLLAASAAGVLVSQTGRLFAADEAPGIDVDPIRTISLQSDRYHGWPTLLRTRDGELLVVCSGGRDSHVCPMGRVELIRSDDDGKTWTYARTILDGPLDDRDAGIVETAKGTLLVTTFTSMAYQPNYEKAVAAAEAGTPYPLAGAQLERWKGAHRRVAEGEHESHLGCWMIRSEDGGLNWSPAYRVPVNSPHGPIALQSGRLFYAGVALWEEGRKVAAYTSDDDGLTWQWIADIPTRDGDEGSKYHELHAVEAADGRLIVQIRNHNKANAGETLQTQSTDGGKTWTAPKSIGIWGLPSHLLRLSDDRLLMTYGHRRKPLGNQARISDDNGETWSPPMLIQSDASSGDLGYPSTVELAPGSFATVWYEKLPDSSNAQLRLATWRLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IS57</accession>
    <name>A0A518IS57_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_18910</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025427">
        <property type="entry name" value="DUF4160"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13711">
        <property type="entry name" value="DUF4160"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="89" mass="10467" checksum="C572D26DDEE119B8" modified="2019-10-16" version="1">MATVTAFQIPGLKIWFWSNDHEPPHFHVKRRGEWEVKVTFMLAPSEMIEVLGSVKPSQRQLKTLTELAVAHRLELLEQWQQIRESETSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IST8</accession>
    <name>A0A518IST8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative ABC transporter ATP-binding protein YbhF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ybhF_4</name>
        <name evidence="5" type="ORF">Mal33_21180</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="15"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="51"/>
            <end position="58"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV56139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="265" mass="29295" checksum="53DE7B8EE5ECC846" modified="2019-10-16" version="1">MRATFSPLFHRRVLISANQLTKRFDNGNQQVTAVEDLSFEVQPGHVFGLLGPNGAGKTTTLRMLLGLIEPTSGDAQIHGFQVSRDADEVKRRIGFVSASVGVYPWLTPREVLHFVGELYGVRHQVASQRIEGLSDLLGLGEILDRRCAVLSTGQQQRMNLARALVHDPPVMLMDEPTRGLDIVGSQVVFDYIVHLRSVGKAVIVCTHRLDEAERFCDSFGLLNHGQLCQHGNLQDLQSRTGRTTLTEMFVDLLAADSSQPTEQPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISV1</accession>
    <name>A0A518ISV1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Xylose operon regulatory protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">xylR_4</name>
        <name evidence="2" type="ORF">Mal33_21500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="1">
        <location>
            <begin position="284"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="394" mass="43895" checksum="1904056798AEDB3C" modified="2019-10-16" version="1">MQPTPRVALFVETSRAYGRGVLKGIWQHVQAHDRWSILFRPRGLEEPTPAWMASWQGDGIIAHVTSLRTAAVLKRSAAPCVDVLGDIPNTGFPVVKTDCLRIAELAFGHLAGLGLKNIGICGMRRGHRPRLDERCDAFQSLAEDAGYDVNIFQPRGGGQYGPSWAKEQKQLVDWVRSLPKPIGIFACNDIRGRETLDACATADIPVPERVAVIGVGNDELLCELSDQRLTSVDVNPIRVGYQAADLLSRMMQGQNVPAKFNVSPRRVVERQSTDMLAVEDPEVADAVKYIRLHACDAIDVNDVVQEVAVGRRVLERRFRDLLGRSLKSEIVRVRLARARELLIETSLSATTISYRCGFSSPAYFMDHFHKKVGVTTKEFRESARREEDPDPDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISV2</accession>
    <name>A0A518ISV2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">kinE_2</name>
        <name evidence="9" type="ORF">Mal33_21570</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="157"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="8">
        <location>
            <begin position="179"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="262"/>
            <end position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV56176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="475" mass="52284" checksum="BD68283EA59679AD" modified="2019-10-16" version="1">MKIAIKMMLVSLSVIAAVTWILSWFLLQQQEDVFLARAEEVAGRFAMETTGTLAERPASERLKICNELTRIPPVAFEYHARWVWFDEQSSSGGPRVAVEVQSLRRQELQSVPIRGPNGQLHLFSYIPVETDQQRPGGLEFVQTMDQLTQARHDSMRAIWTLAAAVMISSTLAVGLASIYFLASPLQRLTNKVARIADGDLSAPLQGHARDELGELADGINAMCERLSETQAAVDAETAAKVSAIEQLRHEDRLRTVGRLASGIAHELGTPLNVIQGRAQLIKGSNGDPQRIETSADEIIKESKRMTTIIRQLLDFARRDTPRRVVCSLNQIAEQTIVLLQTLAERRGVTLRYDHSDDVSGDVDANQIQQVLTNLIVNAIDACDDGGNVMVQVSRCEETAVIEVIDDGQGIDNEDIQQVFEPFYTTKQVGEGTGLGLSIVSRIVQEHGGQIDVQSEPGVQTKFRITLPIVSTDAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISW0</accession>
    <name>A0A518ISW0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_21620</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="114"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="137" mass="14968" checksum="F9329A238ECF51B5" modified="2019-10-16" version="1">MSNATGQLQADWEQYSFFQVPKNWARAIETSPTILALLAIWIGLVSAYDIYLTIKYADSLAYLEQNPVARGILNLDSIQGMGVEHLARFIGLKCGGTVLAIGSLFMISHWKHHLANLAASGVALVQLCVLAFLSFAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISY2</accession>
    <name>A0A518ISY2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Guanylate kinase</fullName>
            <ecNumber evidence="2 9">2.7.4.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 9">GMP kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9 11" type="primary">gmk</name>
        <name evidence="11" type="ORF">Mal33_21850</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Essential for recycling GMP and indirectly, cGMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + GMP = ADP + GDP</text>
            <dbReference type="Rhea" id="RHEA:20780"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the guanylate kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.8" evidence="2 9"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004385">
        <property type="term" value="F:guanylate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00328">
        <property type="entry name" value="Guanylate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008145">
        <property type="entry name" value="GK/Ca_channel_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008144">
        <property type="entry name" value="Guanylate_kin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017665">
        <property type="entry name" value="Guanylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020590">
        <property type="entry name" value="Guanylate_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00625">
        <property type="entry name" value="Guanylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00072">
        <property type="entry name" value="GuKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03263">
        <property type="entry name" value="guanyl_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00856">
        <property type="entry name" value="GUANYLATE_KINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50052">
        <property type="entry name" value="GUANYLATE_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Guanylate kinase-like" evidence="10">
        <location>
            <begin position="7"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="14"/>
            <end position="21"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QDV56204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="200" mass="22737" checksum="E30210F1DAC252EF" modified="2019-10-16" version="1">MKTNTEGRLVIISGPSGAGKSTVVQSLIRECPLPLVLSVSATTRPPRPNERDGREYYFLSNQQFEDLRKDGQFLECEEVFGRGHWYGTLRPQVTTGLKQGQWVILEIDVHGAMRVLEDKELQPITIFLHPGGIEELENRLRARGTETEEAITRRLEVSVGELALMHRYRHEVINDTVDRATSEICEILKSYQERNACSKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IT12</accession>
    <name>A0A518IT12_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">prkC_7</name>
        <name evidence="8" type="ORF">Mal33_22090</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="82"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV56227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="576" mass="63351" checksum="CCA638E7BB33B355" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IT48</accession>
    <name>A0A518IT48_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Complex I intermediate-associated protein 30 (CIA30)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_22500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CIA30 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013857">
        <property type="entry name" value="NADH-UbQ_OxRdtase-assoc_prot30"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039131">
        <property type="entry name" value="NDUFAF1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13194">
        <property type="entry name" value="PTHR13194"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08547">
        <property type="entry name" value="CIA30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CIA30" evidence="2">
        <location>
            <begin position="25"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="186" mass="21143" checksum="571EF71047B7D3C7" modified="2019-10-16" version="1">MILRTLLLIVMLGGSSLMAEDRVLFNFENAEAAKKWQPVNDGVMGGLSDGRFKINEDKNMEFFGTLSLENNGGFASVRSREAKLGLEKDDSIVIRIRGDGRDYNFRLNVPRSVSRNSYEQSFKTKKGEWIEVTLPMDKFVATWRGRVFPNEKFDPSNITGMGIQLSDNNPGSFRLEVEWIKAKRPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITE4</accession>
    <name>A0A518ITE4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">3-oxoacyl-[acyl-carrier-protein] reductase FabG</fullName>
            <ecNumber evidence="2">1.1.1.100</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">fabG_2</name>
        <name evidence="2" type="ORF">Mal33_23450</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.100" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004316">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="262" mass="27639" checksum="44657A6C6515C63F" modified="2019-10-16" version="1">MDLGLKNKLAVITGSTSGIGQAIAKSLLDEGATVVINGRSQTSLARATKELGGGDSLHGVAADVSTADGCAALVAAAEAIAPIDILINNAGIFEPKPFAEISDEDWQRFYEVNVMSGVRMSRAVMGSMQQRGWGRIVFISSESAINIPTEMVHYGMTKTAQLSISRGLAKTLKDTGVTVNCVLPGPTWSEGVEQFVESLAGDQDIEQVKRDFFRDSRGGSLIQRFASVEEVASLVSYVVSQRASATTGAALRCDGGLVDTCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITJ4</accession>
    <name>A0A518ITJ4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_23920</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="594"/>
            <end position="615"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="615" mass="65584" checksum="5548D0D1773FE61F" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IU02</accession>
    <name>A0A518IU02_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Beta-1,4-mannooligosaccharide phosphorylase</fullName>
            <ecNumber evidence="4">2.4.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_25590</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 130 family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007184">
        <property type="entry name" value="Mannoside_phosphorylase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34106">
        <property type="entry name" value="PTHR34106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04041">
        <property type="entry name" value="Glyco_hydro_130"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="SSF75005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV56567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="481" mass="55205" checksum="F050282EDA3D3604" modified="2019-10-16" version="1">MHIQRTGIVLSPNKKRVVLRPFQPPTDDRILRVIARVSTLAEREVDALLNQVYEEFHGRHQKPKAFFEQRFLSIRHHLLTDAPLSENRRLLLGAYFTQEYALESAALFNPSLVWHPDQSNLANGERRFAMSLRAVGEGHISSIVFRSGTIGKDQEIRIDDPVRFVTTPQFVPDSRYENDLFRRKLIELGLGTTFIFEVLSSLETVFTLEQLENRLNISLREHRSQHDELVPLVEQVVMLAKSNYEIQYSPDHELSERVIFPYSPTETNGIEDARFVRFCEDDGRCTYYATYSAYDGKMVLPQLLETADFLQFKMHTLNGPAVANKGMALFPRKINGHYVMLGRQDGEHLFLMYSDLLYFWYTKEMIVKPTNPWEFVQMGNCGSPIETKAGWLVLTHGVGPMRKYCIGAMLLDLEDPSKIIARLQEPLITPNENEREGYVPNVVYTCGALVHENQLVIPYAMSDYATTFATVDLNELLSAMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IU17</accession>
    <name>A0A518IU17_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MORN repeat variant</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_25770</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011652">
        <property type="entry name" value="MORN_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07661">
        <property type="entry name" value="MORN_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="375"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="377"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="429" mass="48071" checksum="83FC52086A860A67" modified="2019-10-16" version="1">MKNRSATRFAIHCILFGSVSLCTLSNLDGDESVLIPSGDFPAIFAPTSEPESPENLPAVAEPEAITPYVAQRFQETNNQLTINPSVPVAEDASDGEIVRERYDDGSVRVERSVMQDEHGNFVNNGTFRMYNPAGSPIAEGHFQMGNRHGEWRRVYATADASLLSAYPYNEFEAPFVSKATFAHGQLHGSWIISDADGKIVSEIPFRNGLRHGQAVWHHPGGERMYIANYRDGMLEGVMAEYDDAGAELTSYTFQDGRRVEREIERYKSQQPKADIRYLSAQQTLKQRDDWWNAKPAVYETSGKRLKHGGFVEYHPNGQKKSTGTYAEGRLTGEFSSWYENGQRETQGFYQDGAPSGAWAWWHANGMRRAEGSYANGAPEGQWTSWTPDGKVAKRQNYSEANQSDIARNRTPAPTPKRPSSASNQRRVQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IU18</accession>
    <name>A0A518IU18_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Flagellar biosynthesis protein, FliO</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Mal33_25760</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044781">
        <property type="term" value="P:bacterial-type flagellum organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022781">
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    </evidence>
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        <source>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
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    </evidence>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
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    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV56584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="208" mass="21749" checksum="2DC017B18F955027" modified="2019-10-16" version="1" precursor="true">MLRYTALLLLALLGMLPVAAQEPLPRVVSNPSYSIQPLNEPAAAEPREAAARTSIPLPPAGSSADPTAPEDKASTGPMFTVISSLAIVLGLFCGFVWLSRKTSGRQGGALDKELFSVLGTSQIDPRHQAALVKCGDRVLLVALTQTGVTTLTEFTEPGEVNDLLARATGKARATFAEAMKDAGDGKTASGFLDSQSAPRRSLFSHSAS</sequence>
</entry>
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    <accession>A0A518IU49</accession>
    <name>A0A518IU49_9BACT</name>
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    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
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                <person name="Amann R."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="13 14">Mal33</strain>
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    <sequence length="683" mass="74072" checksum="86EC551C5A518297" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
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                <person name="Overmann J."/>
                <person name="Amann R."/>
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                <person name="Devos D.P."/>
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                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
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    </dbReference>
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        </location>
    </feature>
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            <dbReference type="Pfam" id="PF00487"/>
        </source>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
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    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IU90</accession>
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    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.</text>
    </comment>
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        <property type="protein sequence ID" value="QDV56652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1730.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038377">
        <property type="entry name" value="Na/Glc_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001734">
        <property type="entry name" value="Na/solute_symporter"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00474">
        <property type="entry name" value="SSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50283">
        <property type="entry name" value="NA_SOLUT_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="74"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="115"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="159"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
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            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
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            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
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            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
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            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="387"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="413"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="439"/>
            <end position="462"/>
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    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="616"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="695"/>
            <end position="716"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV56652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="720" mass="78247" checksum="548C0C68AE14E165" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IU98</accession>
    <name>A0A518IU98_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_26500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="243"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="276"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="314"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
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            <end position="464"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
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            <end position="488"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
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            <end position="526"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="546"/>
            <end position="565"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="582" mass="63555" checksum="E6A2315239E19F82" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUE3</accession>
    <name>A0A518IUE3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glucose 1-dehydrogenase 2</fullName>
            <ecNumber evidence="1">1.1.1.47</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ycdF</name>
        <name evidence="1" type="ORF">Mal33_27010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="GO" id="GO:0047936">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
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    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="265" mass="28619" checksum="0D74ACE463F468B0" modified="2019-10-16" version="1">MSKLSGKRALVSGAGRGIGAAAAIELARAGADVAINYLDDAEEAEGVCEQCRGLGVRAVSVQADTGVQDEAERLVDQAWEALGGLDIVVSNAAYSDRELFYRADLDGFRRTIDVTMWGPFYLLRSASRKMIDAGIQGSVVVVSSPHAVQAMPGAMAYNMAKAAIDQMARTAAVELAQHRIRVNLLHPGWIDTPGERKFFSEQTLQEKGAELPWGRLGQPQEIGRGIVFLSDPASEYITGSTLTIDGGIQLPWRDMFRIDEKPQAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUE4</accession>
    <name>A0A518IUE4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF58 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_27140</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002881">
        <property type="entry name" value="DUF58"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01882">
        <property type="entry name" value="DUF58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF58" evidence="1">
        <location>
            <begin position="43"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="297" mass="34424" checksum="78C2712DF4E4FF8F" modified="2019-10-16" version="1">MSAESYLKPEVLNQIKRLDLRAQMVVRGFLQGLHASPYHGFSVEFSEHRRYSKGDDPKTIDWLVYAKTDKYYVKRYESETNLTGYLMMDLSRSMGFTHRQQFSKFEYSICLAASLCYLMIMQQDPVGLLTFSDKLRANLPARSRRSQVTDLLAQLSRLKPEGETDLGDSLHRVAAMLPHRSLLMIFSDLLGDPEPVYRALAQLRHAGHDVILFHILDESEVHFPYDGPVEFEDPETGQKMPVDATEIRQDYLEAIEEFREGYRERCSKLRVDYVPLDTSMPFDKALTEYLASRQSRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUG8</accession>
    <name>A0A518IUG8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_27260</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035069">
        <property type="entry name" value="TTHA1013/TTHA0281-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143100">
        <property type="entry name" value="SSF143100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="34"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="71" mass="8015" checksum="87BB373A7EC8C2B8" modified="2019-10-16" version="1">MLTPHFNAVIRRDGQWWIGWIEEIPGVNSQGATRDELIANLRDALAEAIELNREDARRAAGEAYEEVAIQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUJ5</accession>
    <name>A0A518IUJ5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cytochrome C assembly protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_27580</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002541">
        <property type="entry name" value="Cyt_c_assembly"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01578">
        <property type="entry name" value="Cytochrom_C_asm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="75"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="99"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="137"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="188"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="221"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="251"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrom_C_asm" evidence="3">
        <location>
            <begin position="73"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="276"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV56759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="304" mass="32801" checksum="B1FC9F750B0EA8FC" modified="2019-10-16" version="1">MQHLSQITVTCFVGSYIVALLLEITRGMFRLPGRMAGVIGFTAAGLYTHVAYLTMSARQQMDGAQMGLLASWYDWTLLLALGVAICYAILLLRRPDSTLGYFLLPLILSLIGLAGVLRNSAPFSRDEATGFWLNMHAGSMLLVTVAVLLGFVAGVVYLVHSYRLKHKRLSSAGMRLPSLEWLQTVNRVCLLTSTCLMAVGLFAGIAMHLNRSGEIVWTNRGIALSCVLFAWLVIATLFEALYKPARRGRKIAYLTLASFGFLVLAMAGLFTSNHGASGEPPSGKTEATAEATLPGVNPEKGGAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUX5</accession>
    <name>A0A518IUX5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">EamA-like transporter family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_28940</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="167"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="198"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="228"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="253"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="2"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="141"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="282" mass="29479" checksum="8A55F16F6A232458" modified="2019-10-16" version="1">MVISMAAFAVEDTLVKAAAAVLPVGQILIIFGFGGALLFACIAKLNRDQLFTSDAFSPAMRFRMLFETAGRLFYVLAISLTPLSATTVILQATPLVVILGAAIVFNEKVGVRRWIAVFVGLIGVVIVVGPGSDSFSMLSVLAVIGLLGFAGRDLASRAAPITVSTAILGLYGFLSVLVAGVLISAWGRASFVWPNVDASLYLAGSVLVGVAAYASLMKAMRTGEVSAVTPFRYTRLLFGVGLGVLLFGERLSVQMLIGSGLVIVSGLCILWKKKPAVAASQC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IV44</accession>
    <name>A0A518IV44_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Chemotaxis protein CheW</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">cheW</name>
        <name evidence="2" type="ORF">Mal33_29490</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039315">
        <property type="entry name" value="CheW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036061">
        <property type="entry name" value="CheW-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002545">
        <property type="entry name" value="CheW-lke_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22617">
        <property type="entry name" value="PTHR22617"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01584">
        <property type="entry name" value="CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00260">
        <property type="entry name" value="CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50341">
        <property type="entry name" value="SSF50341"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50851">
        <property type="entry name" value="CHEW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CheW-like" evidence="1">
        <location>
            <begin position="12"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="151" mass="16195" checksum="C4732A9D76C9C411" modified="2019-10-16" version="1">MSKTAEKTNVGVQQFATFYVSDILLGIAIDRVREINRLSEITCVPHAPTHVLGVVNLRGEVVPLLDLGLLLGLAKTQVSSDSKNMIVQAEGQLLGLVVDRVSDILTVSQDDMSSPPANVNSVDGRMILGIHTLPEDVVILLDIDQALANSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IV48</accession>
    <name>A0A518IV48_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_29510</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="82" mass="8875" checksum="98054E742E8D95B0" modified="2019-10-16" version="1">MSMVLLCATTIVTSGTSRLPDSFAQEIFAASSAARTSDVNFTAYVSRAMNQVIPLHSRGTYLISSEATSCRTKTKKYSMNLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IV69</accession>
    <name>A0A518IV69_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Dehydrogenase</fullName>
            <ecNumber evidence="3">1.1.1.18</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_29850</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.1.18" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050112">
        <property type="term" value="F:inositol 2-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GFO_IDH_MocA" evidence="2">
        <location>
            <begin position="5"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="339"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="365" mass="39175" checksum="34C10C0F8E007F2A" modified="2019-10-16" version="1">MTRLKLGVIGAGHLGKIHAKLLSTIDDVQLVAVSDPFAAARQAIEDQFSVPTFADYRDLLGLVDGVILAAPTDLHAEIGSDVLRAKKHLFIEKPITTTSEDADRLVALAKQNGCTLQVGHVERFNPAWSAAESMLEHPKYIEAVRASSFPGRCLDVGVVMDLMIHDIDLVLSLTSAAVQRIDASGLSVISDHEDVAEARITFECGLVANLKASRISPAAARTMQVYGPRGYANIDFSGPSATLIQPEASIAERSFELTAAGPLADFREQLFSHWLASQSPEIQPRNAILDEQHDFVISIQSGSQPTVSGADGARAVAVAEQVLEAIDCRQWLGDASEPEQVGAYATPPESVEAASQRIHQQRKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVN5</accession>
    <name>A0A518IVN5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">PMT_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Mal33_31450</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038731">
        <property type="entry name" value="RgtA/B/C-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13231">
        <property type="entry name" value="PMT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="93"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="134"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="179"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="219"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="364"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="396"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="domain" description="PMT_2" evidence="9">
        <location>
            <begin position="72"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV57144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="456" mass="50204" checksum="7E34C46220055D26" modified="2019-10-16" version="1">MSDPARCCSLPLRLILPLMLLALLVRGGVMTWRYDHLQQDPDAYRLLAENLANHNVYGQVDADGQARPTAFRPPGYPWLLSWFVTDGQLGSPAAAALNLAFGLATVGLVFAIGSRLQSQVTGFVAAALVAIDPILLGQSTLVMTETLATMLAALIWWLFLRNEATLQPSGTSSSTLGWSLALAVGLAAGFFCRPVFIVWAAWMLLMLFLRGRRQVGRTAITIATVGLVMLLAVGGWTWRNQSVMGKPIWATTHGGYTLLLGNNPPFYEYLAEGKVGEKWDAEFFHRRWAERFSADPRELSFWTAETIDTTHAAAPLGEIDDDRLAYESAKATIRRQPQMFVASCLVRLGRLWSPMPHAGDYSNLLRYAIGSFYVALFACCLLGIWRLGRRLMSPAWMAMLLLAVALSCVHSIYWSNMRMRSLATPLIAVVAAVGILGDRQRASCQPSPIVPLKSQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVY1</accession>
    <name>A0A518IVY1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_32480</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021760260" evidence="1">
        <location>
            <begin position="24"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="107" mass="12008" checksum="D2D1811D2C6AB668" modified="2019-10-16" version="1" precursor="true">MFKRLLLLCAAVAILSASSTAMARYPYRMGYRGYYAPAPVVRAYRPAYTYSYRAPYTSYYAPRASYYVAPPVRRYYAPPAVYAPVPVYAPYGGVSVRSPGMSLRIGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVY4</accession>
    <name>A0A518IVY4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acetyl xylan esterase (AXE1)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_32500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008391">
        <property type="entry name" value="AXE1_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05448">
        <property type="entry name" value="AXE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021743707" evidence="1">
        <location>
            <begin position="25"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="domain" description="AXE1" evidence="2">
        <location>
            <begin position="110"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="704" mass="75856" checksum="CB2BC4C00078FAE9" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVZ3</accession>
    <name>A0A518IVZ3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 16">Homoserine dehydrogenase</fullName>
            <ecNumber evidence="6 16">1.1.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="primary">hom</name>
        <name evidence="19" type="ORF">Mal33_32600</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>L-homoserine + NAD(+) = H(+) + L-aspartate 4-semialdehyde + NADH</text>
            <dbReference type="Rhea" id="RHEA:15757"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57476"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:537519"/>
            <dbReference type="EC" id="1.1.1.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 16">
            <text>L-homoserine + NADP(+) = H(+) + L-aspartate 4-semialdehyde + NADPH</text>
            <dbReference type="Rhea" id="RHEA:15761"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57476"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:537519"/>
            <dbReference type="EC" id="1.1.1.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4 16">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 3/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 16">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 3/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 17">Belongs to the homoserine dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.3" evidence="6 16"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00050">
        <property type="reaction ID" value="UER00063"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00051">
        <property type="reaction ID" value="UER00465"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004412">
        <property type="term" value="F:homoserine dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005106">
        <property type="entry name" value="Asp/hSer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016204">
        <property type="entry name" value="HDH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001342">
        <property type="entry name" value="HDH_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019811">
        <property type="entry name" value="HDH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01842">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00742">
        <property type="entry name" value="Homoserine_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03447">
        <property type="entry name" value="NAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000098">
        <property type="entry name" value="Homoser_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01042">
        <property type="entry name" value="HOMOSER_DHGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 16" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="16" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="9 16" id="KW-0412">Isoleucine biosynthesis</keyword>
    <keyword evidence="13 16" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="11 15 16" id="KW-0521">NADP</keyword>
    <keyword evidence="12 16 19" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 16" id="KW-0791">Threonine biosynthesis</keyword>
    <feature type="domain" description="ACT" evidence="18">
        <location>
            <begin position="394"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="14">
        <location>
            <position position="246"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <begin position="50"/>
            <end position="57"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="146"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="231"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00006753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR000098-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR000098-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU000579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU004171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="QDV57256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="477" mass="50879" checksum="6B571B5C190DC039" modified="2019-10-16" version="1">MDYGRPYALFKAAVLVANGGNVYHSEHQNLNNICDLKINRTMEKTKVAIVGLGTVGTGVAKLLLDHGDRTARHAGRTLWLQRAVVRDASKPEYADLPEGVVTEDLDDVLNDPEIKVVAQLIGGLEPARTIMLKLLESGKDVVTANKALLAEHGPELFGRARELGQCIAFEAAVAGGIPIITNISQCLSANQILSLEGILNGTSNFLVTQMDRLGMSFDDAVAQAQELGYAEADPTMDVDGTDAAQKLAILAHLAFGAHPRWADIPRLGVDQLDPADLQYARELGYRIKLLAVARLGSEGLELHVSPTLVKAGTPLAEVQDAFNAIAVCGDAVGPVFYHGLGAGQMPTASAVVADIIDTAVGRTRLTFQTLKQFNGDEQPRVSLRPFSELPGRYYLRLHVTDSPGVLGEITGVLGRHQVSIASVIQHEPASDGTNDVVPLVIMTHSAPEGAAGRAANEIENLDCVVGKVIRLRVKVGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IW63</accession>
    <name>A0A518IW63_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_33340</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="125" mass="14334" checksum="1A2EF8B63C371EBD" modified="2019-10-16" version="1">MISIQLDREEGVYSPGDLLECNWRIGRIGLDGIQSVEASVLWYTEGKGDEDFSVHHFVRVSGEQLRKLGDSYQHSLVTALPMSPLTYDGQLLRIRWCVRLRIFLPNENDTVWQQPFFLGYADSDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IW82</accession>
    <name>A0A518IW82_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_33540</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="146" mass="14901" checksum="77E4D7ED42DB9F74" modified="2019-10-16" version="1">MHSTSTSRSTDTRHFILSLLTTFSLVVSIGCDHEPDYLHPGAPVSITILSSGTPVAGGQLNLSGQGGGAALDAQGLANLEHVPYGTYKVVLLAPEPDPVPPEPGTAAASAAAEVSFPKELGSEATTTLSITVAEGTENTFTLDIAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWA5</accession>
    <name>A0A518IWA5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Capsule biosynthesis protein CapB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">capB</name>
        <name evidence="2" type="ORF">Mal33_33790</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016879">
        <property type="term" value="F:ligase activity, forming carbon-nitrogen bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045227">
        <property type="term" value="P:capsule polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008337">
        <property type="entry name" value="Capsule_biosynth_CapB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01758">
        <property type="entry name" value="CAPSULEPROTB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04012">
        <property type="entry name" value="poly_gGlu_PgsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mur_ligase_M" evidence="1">
        <location>
            <begin position="38"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="410" mass="44597" checksum="9390B46C066C9585" modified="2019-10-16" version="1">MDGTLVMAGGALALSAAGIAESWWHNHNLHKIPVRIHVNGTRGKSSVTRLIAAGLRAGGIRTCAKTTGTVPRMIFPDGSEASVFRPSRANVIEQRRVVRAAARLGAEALVVECMALQPQLQSLCELQLIQSTHGVITNARADHLDVMGPDVRGVARALAGTVPVGGTMYTAEQRQMPRDVIAAAAKDRGSKMVSILDDSVAEVTWDELAGFSHIEHPDNLALALRICSDLGVDRQTALQGMWAADADPGVMRLYRIADPEREMVFVNGFAANDPESTGHSWNTLFDRYEKVERRIALFNCREDRIDRSLQLADACVRWRPADHYILSGTGTETFARRAIQKGLSKDRLTCAEHQPAARIVELMQGQSGRSSMVMGMGNIAGPGMDLLNYFQHAQDSGSCETHQPQLQEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWB6</accession>
    <name>A0A518IWB6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">50S ribosomal protein L1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8 10" type="primary">rplA</name>
        <name evidence="10" type="ORF">Mal33_33840</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.</text>
    </comment>
    <comment type="function">
        <text evidence="8">Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8 9">Belongs to the universal ribosomal protein uL1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00403">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01318_B">
        <property type="entry name" value="Ribosomal_L1_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005878">
        <property type="entry name" value="Ribosom_L1_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002143">
        <property type="entry name" value="Ribosomal_L1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023674">
        <property type="entry name" value="Ribosomal_L1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028364">
        <property type="entry name" value="Ribosomal_L1/biogenesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016095">
        <property type="entry name" value="Ribosomal_L1_3-a/b-sand"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023673">
        <property type="entry name" value="Ribosomal_L1_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00687">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002155">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56808">
        <property type="entry name" value="SSF56808"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01169">
        <property type="entry name" value="rplA_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01199">
        <property type="entry name" value="RIBOSOMAL_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0678">Repressor</keyword>
    <keyword evidence="7 8 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="6 8 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 8" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="4 8" id="KW-0810">Translation regulation</keyword>
    <keyword evidence="8" id="KW-0820">tRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV57379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="225" mass="23852" checksum="B84B408B4CA0487B" modified="2019-10-16" version="1">MPQQSKRYRAMAAKASAEPKPLSEAVVSLKEFNTTKFDQTVEIHMRLGIDPNQADQIIRGSLVLPHGIGRTQRVVVFAKGEAAEAAKAAGADEVGQEDLAKRIKDGWTDFDVCIATPDMMGVVGPLGRVLGPRGLMPAPRAGTVTPDAGKVVAEYKAGKVEFRNDKGGNVHAVVGKLSFDAEKLSENIQAFIDLVVGMKPQSVKGTYLKGIAIAATMSPSVRVAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWW6</accession>
    <name>A0A518IWW6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Molybdopterin adenylyltransferase</fullName>
            <ecNumber evidence="4">2.7.7.75</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">mog</name>
        <name evidence="4" type="ORF">Mal33_35770</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.75" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00344"/>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061598">
        <property type="term" value="F:molybdopterin adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00886">
        <property type="entry name" value="MogA_MoaB"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036425">
        <property type="entry name" value="MoaB/Mog-like_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="MoaB/Mog_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008284">
        <property type="entry name" value="MoCF_biosynth_CS"/>
    </dbReference>
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        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="molyb_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MoCF_biosynth" evidence="3">
        <location>
            <begin position="10"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV57566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="185" mass="19803" checksum="D868DDC5DF46A859" modified="2019-10-16" version="1">MTQPTPASIGIVTVSDRASRGEYQDRGGPAIEAYLQEVLQSPWQAVPRLVPDDIDAIADALQELSEQGCCLIITTGGTGPALRDVTPEATERVCDKMMPGFGEQMRQVSLQFVPTAILSRQTAGICGSSLIVNLPGQPKAIAECLDAVFPAIPYCIDLLEGPRLETDPARCQAFRPKSKPAPDPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IX64</accession>
    <name>A0A518IX64_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Peroxiredoxin bcp</fullName>
            <ecNumber evidence="5">1.11.1.15</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">bcp_4</name>
        <name evidence="5" type="ORF">Mal33_36880</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.11.1.15" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024706">
        <property type="entry name" value="Peroxiredoxin_AhpC-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000239">
        <property type="entry name" value="AHPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1 5" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="4">
        <location>
            <begin position="5"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine sulfenic acid (-SOH) intermediate" evidence="3">
        <location>
            <position position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000239-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV57675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="159" mass="17505" checksum="34CE96217D7549A3" modified="2019-10-16" version="1">MSDWIEAGQKAPAFNLASDEGGKIRLSSLKGSPVVLYFYPKDDTPGCTKEACAFRDRCEEIQALGATVLGVSPDDTASHAKFRSKYELNFPLLADPDHKVAEAYGAWREKNMYGKISMGIQRSTFVIDAEGKVAKVWKRVKVDGHDQHVIDAIKALTEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXF8</accession>
    <name>A0A518IXF8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">TPM_phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Mal33_37790</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007621">
        <property type="entry name" value="TPM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04536">
        <property type="entry name" value="TPM_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="47"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="228"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="255"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="domain" description="TPM_phosphatase" evidence="6">
        <location>
            <begin position="82"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="15"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV57765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="305" mass="32785" checksum="82385094BF80A9C8" modified="2019-10-16" version="1">MTASKQSTPGMEVSKELESVDEQQREIARVGSKDKGEIEMTSRRRSGAFVCCAAIIAYGLLAASPASAIEIDLQPPGEREFVRDLAGMLDPGAKEQIQELCDSLLTDKATPIIVITIESMAQYGGEGLRIETFATLLFDQWGIGQATLGDQEWNTGILLLVSKNDRKARIELGGGWGRREDALCRQIMDDYIVSEFKQGRFSEGIVAGVEALDTMARKLQLPTRPRPWWHYALGVGFVGLAIFTIVSLVRNGSSGWAWLFWGAIFTVLGVILYQMMTSRGSGGGGFSGGSFGGGSSGGGGATGSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXT2</accession>
    <name>A0A518IXT2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_39060</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="79" mass="8947" checksum="C8AA3ACC32DFA329" modified="2019-10-16" version="1">MQPNTPAFERWVRWSPQAIKRRDIKLIVCRVTAMVEASVHRWFQRADDACSVSIALGCLGFSYSGGSLSLRTTCMGRNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXZ8</accession>
    <name>A0A518IXZ8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_39740</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="227" mass="24956" checksum="BB6FB60F23DF1597" modified="2019-10-16" version="1">MGNNLENFEQTVQRVTEAVLGCIRQREGFKEVIVSKPDCIYVKSANGVIQQVNTAYHGRFSAGADPAGKSGVSYLHPSVVDASHRSDKMILGGCSSVLFNHQGEDQQGRSLRYRTYKRSLQEAGDPRYAILGITRVMGIVGTKVNAASMLSEKWQRFEQLSPEDRQIAIAMASSDPAAALAERGDVPHGRLKSRREAILKTLQIESEVELIKLLVRLQDNGFGNLGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IY22</accession>
    <name>A0A518IY22_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_39920</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="10"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="46"/>
            <end position="53"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV57976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="260" mass="27814" checksum="FFDB39661E5BFDFE" modified="2019-10-16" version="1">MSQENLAAPLSVRNATKTFRQGERAIDALKDVDLTVEHGSFVAVMGASGSGKSTLLHLMAGLTRPTEGAVFVDGQDLATLSDRKLTEYRRDHIGLVFQSFNLVPALSAADNILLPLYAAGLKEPQKSSLAELAKRLGIADRLTHRPDALSGGQQQRVAIARALATDPAIVLADEPTGSLDSVTGQAICKLLRELCDQQQRTIIVVTHEPSVAIWSDRVVILKDGQIVESLSTNEYNDAQALAAHYQEILGAGEPAMASSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IY86</accession>
    <name>A0A518IY86_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Aminotransferase</fullName>
            <ecNumber evidence="4">2.6.1.98</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_40590</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the DegT/DnrJ/EryC1 family.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.98" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00616">
        <property type="entry name" value="AHBA_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000653">
        <property type="entry name" value="DegT/StrS_aminotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30244">
        <property type="entry name" value="PTHR30244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01041">
        <property type="entry name" value="DegT_DnrJ_EryC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000390">
        <property type="entry name" value="PLP_StrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="190"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="2">
        <location>
            <position position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR000390-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000390-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV58042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="383" mass="41678" checksum="A59ABDEE7FC3F109" modified="2019-10-16" version="1">MADEPNVPLLDVGRGNAPLRQEMLAAIGDVIDSGRFLYGPDVSALENEIATLSQVDHAIGCASGSDALLLALMALEIGPGDEVIVPSFTFFASVSCIERLGATPVFVDILPDTFNIDHTAIEAAITPATRAIIPVHLFGQCAAIDKICQIGEKHGIAIIEDAAQAIASAYHSRPAGSWGRIGCFSFYPTKNLGGMGDGGMMTTNDPQVADRLRLLSAHGMRPRYHHRALGINSRLDTFQAAVLRIKLKHLPEATASRQTNATRYRDMLQAADLHKHFTLPTLDPNAYHVWNQYSIRVPDGQRDALREHLASNGVGSEIYYPVPMHQQECFAHVTVEPGSLPETERAAAEILNLPIFPELEESEQERVVSVLRGFYEGRQKAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYI3</accession>
    <name>A0A518IYI3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Molybdenum carrier</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_41700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024755">
        <property type="entry name" value="cpYpsA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12694">
        <property type="entry name" value="cpYpsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="160" mass="17676" checksum="650461B598284954" modified="2019-10-16" version="1">MTQAVFSHIPQRIVSGGQTGVDRGALDAAIALGIPHGGWCPRGRLSEDGQIPARYDLTEHASPRYKDRTLQNVLDSDATLILYCDTLRGGTRLTQRYAVDAGKPQLAVAIDVDWSVESVRRWLYQYQPLALNIAGPRESNFPGVQVLSREAVLRIFDSSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYP5</accession>
    <name>A0A518IYP5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_42280</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011446">
        <property type="entry name" value="BBP7"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07585">
        <property type="entry name" value="BBP7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="590" mass="63048" checksum="10206DBF0CD292DB" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYR3</accession>
    <name>A0A518IYR3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">pknB_19</name>
        <name evidence="8" type="ORF">Mal33_42510</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="35"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV58233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="781" mass="85242" checksum="193ED50D3B8328EF" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ16</accession>
    <name>A0A518IZ16_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_43370</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="389" mass="44490" checksum="9B5C55DC4982AE36" modified="2019-10-16" version="1">MFETQRRNFLRLPILAAATIGMQRFSDADEPRQKTTQIDPRGYFTVDRRNDRWWMIQPDGSVNFSLGLNHIDPEPLRQGEDDRLWQKRYAADVQRWLAESVRKNLLDWGFNTVGLTADVIALENDDRRLGGGLSPAQLRSLQMPYGYLLPFAQPDPETGELPPNDYLGQPFARWCDRIARQHCAAVRDDRQLIGYWSAERPDWSQARFSSRSEMANQATGYYQTIRTAIRRYDPHHLILGDRYDASRSLSATVVRAALPHVDLLSVDCSGDAVNVHRQLSKMAQLFDRPILVADHAIDRQPHNNAWPPQENRFHDPRGYRRTVEMLTAIPQVVGYHLCGGYLPSQLLRRGLMDAQERPDRLAIEGIRTTNAAVKRWVADTGDSPLEPPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ50</accession>
    <name>A0A518IZ50_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Glutamate--tRNA ligase</fullName>
            <ecNumber evidence="8">6.1.1.17</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">gltX_2</name>
        <name evidence="8" type="ORF">Mal33_43820</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.17" evidence="8"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004818">
        <property type="term" value="F:glutamate-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043039">
        <property type="term" value="P:tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000924">
        <property type="entry name" value="Glu/Gln-tRNA-synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020058">
        <property type="entry name" value="Glu/Gln-tRNA-synth_Ib_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00749">
        <property type="entry name" value="tRNA-synt_1c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00987">
        <property type="entry name" value="TRNASYNTHGLU"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 5 8" id="KW-0436">Ligase</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA-synt_1c" evidence="7">
        <location>
            <begin position="16"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV58364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="331" mass="36814" checksum="1BD0774C761EEA85" modified="2019-10-16" version="1">MEGFASMPQNEPPVGRLAPSPTGAQHLGNARTYILAWLSIRSRGGRVVLRIEDIDSPRVKPWAVQQAIDDLAWLGLDWDEGPDIGGSHPPYIQTQRIDRYSAILDRLRDQELLYPCACTRKDIEEAASAPHEAHDGPVYPDTCAGWRVGDPLPESGHFCWRFRSRRQRVSFVDRVAGPQSKIPHAELGDFPVTRKTGEAAYQLAVVADDIAMGITEVCRGDDLLSSTFRQIDLFDALGHPLPQFVHVPLVVGSDGRRLAKRHGDTRLSYFRERGARPESIVGWALWSAGLIESWQPIQPQEFVESFDLDAIAAGETIVAPTDYQKIIDASF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ57</accession>
    <name>A0A518IZ57_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alpha/beta hydrolase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_43880</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="domain" description="Hydrolase_4" evidence="3">
        <location>
            <begin position="130"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV58370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="371" mass="40215" checksum="4A8952F49479F222" modified="2019-10-16" version="1">MKQHPRAITLASDSTLKTTIGLRVFLIMCCVAAMSVAAWGQGPAFDPLAPGNRRPMPTPQQPNTPPARPAQAAPTGRPVASVPPKTTRPNTSNKRKKIPEELKPRLEKITTKDGVQLQIGYFPSDKGKKAPTVLLVHEWSGQTSPYVPLAFKLQAEGCAVALLDIRGHGRSRVMGPDGKPIEVDRATKRDLEAVVALDMEAAKKFLRSENDAEKLNLNALAVIGIEEGSLLALNWAMMDWNWPSIGTKKQGQDVKALVLVSPIKSVNGVSGDMATRHPAISRLPVMIVSGSSISENSEANRLSKLFERARVTGKYNNAQPLPVKAMRVRANLSGVDLILRGPGVVDGIASFVKENLVDNMDVLPWVQRNDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ91</accession>
    <name>A0A518IZ91_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_44210</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011447">
        <property type="entry name" value="DUF1552"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07586">
        <property type="entry name" value="HXXSHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022189692" evidence="1">
        <location>
            <begin position="40"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="433" mass="46966" checksum="919DDB3F8C4E4FE0" modified="2019-10-16" version="1" precursor="true">MFSSIEFNFRKRLPRRTMLRGTGVSLAIPHLSAMQSAFADPTTNQGPPKRFVAMTLGLGLHGPNLNPAEAGKEFKPSRYLKPIEDLRSSYTVISGSSHPGVGGGHKAEASILTARNVGASGGGRNSISLDQYMAKHLGGETRFPSLVLSSAGSNSPSYTDNGSMIPAQDRPSRLFDQLFVDDSPAARDQQAQRVREGRSIMDLVSDDAKRLSNSLGASDRDRMDAYFTSVRDLELRMAASEEWALRPKPKVDAKRPIDIGNGNDFVGRQRLMSDMIRLALETDSTRYIVYHLGGSGGVVPLPGVEEGYHSLSHHGLDEEKLEQLAVVETAIIAAWGDFLRSLGQTDDQGNSLLDQTSVLLTSNLGNASNHSNQNMPVLLAGGGFRHGQHLAFDTKNNYPLPNLYVSLLQDQGLPVDQFASGTSTMRGLEFKNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZA5</accession>
    <name>A0A518IZA5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">MotA_ExbB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Mal33_44430</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the exbB/tolQ family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002898">
        <property type="entry name" value="MotA_ExbB_proton_chnl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01618">
        <property type="entry name" value="MotA_ExbB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="119"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="158"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="267"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="311"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="domain" description="MotA_ExbB" evidence="8">
        <location>
            <begin position="230"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV58422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="547" mass="58491" checksum="C4CEBB76531F51B0" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZA9</accession>
    <name>A0A518IZA9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Tyrosine recombinase XerC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">xerC_1</name>
        <name evidence="10" type="synonym">xerC</name>
        <name evidence="15" type="ORF">Mal33_44470</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
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        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the 'phage' integrase family. XerC subfamily.</text>
    </comment>
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    </dbReference>
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        <property type="entry name" value="CB"/>
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        <property type="entry name" value="DNA_brk_join_enz"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="recomb_XerC"/>
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    </dbReference>
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        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="4 10" id="KW-0132">Cell division</keyword>
    <keyword evidence="5 10" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="3 10" id="KW-0963">Cytoplasm</keyword>
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    <keyword evidence="7 10 11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
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        </location>
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        <location>
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        </location>
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        </location>
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        <location>
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    </evidence>
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        </source>
    </evidence>
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        </source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS51900"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="299" mass="33853" checksum="F82457507FBD2D2D" modified="2019-10-16" version="1">MRSAIPQFLQYLAHERNASDLTIKAYREDLFGLVEFLEDQRGSTPKPQDLSPQDLRGYQAALQEADYARNTISRKLASLRSFYRFAQRQELATTNPASPLRNPRRQRKLPHVLSGGEVNRILKTPPVNDPNGLRDRAILETLYSAGLRVSELVGLNDGDLDFDQQIIRVRGKGRKERMSPLGSFAIRALRRYMPTRNRDPKEPQSPSAATFLNRFGRRLTTRSVGRMLEKHIQVAGLDTRTSPHTLRHSFATHLLDAGADIRSVQELLGHKSLATTQIYTHVSAANLLAIYEKAHPRAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZC2</accession>
    <name>A0A518IZC2_9BACT</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_44600</name>
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        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
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                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
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                <person name="Bruemmer F."/>
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                <person name="Spormann A.M."/>
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                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">Mal33</strain>
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    </reference>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="QDV58437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="183" mass="20284" checksum="2F76C7E2FA83E264" modified="2019-10-16" version="1" precursor="true">MSTRFIARLTALTLLATCSPIALADDDKKDAKLNDSVMQRLQGRWEVVGGVNQGRELSEAELKGTYNTVATNTITTYDRNEHQRFRAVFSIDSAEDPIQINMTSVPQKSTVAKRDLKVPTEDIVAAGILKFEGVDKWTLCYALPGNDRPTKFESPEGSKVMLFHLVRRQGDPVPDGRSASKTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
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    <name>A0A518IZJ7_9BACT</name>
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        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
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        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
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        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Boedeker C."/>
                <person name="Pinto D."/>
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                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
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                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="Aerotolerance_reg_N"/>
    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
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        <property type="entry name" value="Double_TM_dom"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="CARDB"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="VWA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="713"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="domain" description="BatA" evidence="2">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
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        <location>
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            <end position="198"/>
        </location>
    </feature>
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        <location>
            <begin position="246"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV58518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="740" mass="80016" checksum="C6EFEAC340928FDC" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZR4</accession>
    <name>A0A518IZR4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_46090</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="146" mass="15855" checksum="DF37A534ECA84886" modified="2019-10-16" version="1">MAFAWFVLFAGGGRLMYIAAASLGLLIGLGEVVPWLMPWATCCRSCRNWCARKIGAELGSLVGLYSAACEWMARSEWARLFCDGSRIATVQCVVDRVCLVIVFGAWCLLRIEGQCGFEKFSDCTAVRESPGTKLGGSQAGEQSIQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZW9</accession>
    <name>A0A518IZW9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">UvrABC system protein A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">uvrA_3</name>
        <name evidence="9" type="ORF">Mal33_46560</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009380">
        <property type="term" value="C:excinuclease repair complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004602">
        <property type="entry name" value="UvrA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041102">
        <property type="entry name" value="UvrA_inter"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17760">
        <property type="entry name" value="UvrA_inter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00630">
        <property type="entry name" value="uvra"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="663"/>
            <end position="991"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="695"/>
            <end position="702"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV58632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="999" mass="109049" checksum="37BBE455890F0B99" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J091</accession>
    <name>A0A518J091_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative polyketide biosynthesis zinc-dependent hydrolase BaeB</fullName>
            <ecNumber evidence="2">3.-.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">baeB_2</name>
        <name evidence="2" type="ORF">Mal33_47820</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.-.-.-" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050313">
        <property type="term" value="F:sulfur dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07724">
        <property type="entry name" value="POD-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044528">
        <property type="entry name" value="POD-like_MBL-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="1">
        <location>
            <begin position="278"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodanese" evidence="1">
        <location>
            <begin position="379"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="474" mass="51204" checksum="2693E72BB3C5E666" modified="2019-10-16" version="1">MLLKYFYDEKLAHASYLVGCQRDKVAVVVDPGRDIEPYLAMAAKEGLKLVGVAETHIHADYVSGARELADRVDATLYVSDEGPADWKYLFLDGYKSVLLHDGDHFMVGNIRLDVLHTPGHTPESISFMLTDEGGGANKPMGIFTGDFVFVGSIGRPDLLEEAAGLTGTAEPGARDLYKSAERFKALPDYLQVWPAHGAGSACGKGLGAIPSSTVGYEKLFNPALQFDDEEAFVRYILADQPEAPKYFAVMKRVNKEGPRVLGAGHHHNMLPIAGLADAVQAGNVVDLSAAPEFGKAHYPGTINIPVGMLAAWAGWLVDYDKPNYLICEPQQLEAAARVLHKIGVEEILGAFDTNEVRSQGLANESYPTCSPDELAAKIETGDVKLIDVRSDEEWNEGHIAAAEHRFLGRLPRTLAELPRDQKLVVQCRSGARSAIGVSVLQAAGFKNVVNLTGGYNAWKAAGLPSVKPQHAMSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0C0</accession>
    <name>A0A518J0C0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Endoribonuclease YbeY</fullName>
            <ecNumber evidence="7">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 8" type="primary">ybeY</name>
        <name evidence="8" type="ORF">Mal33_48180</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 1 zinc ion.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the endoribonuclease YbeY family.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="7"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:endoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00009">
        <property type="entry name" value="Endoribonucl_YbeY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023091">
        <property type="entry name" value="MetalPrtase_cat_dom_sf_prd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002036">
        <property type="entry name" value="YbeY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020549">
        <property type="entry name" value="YbeY_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02130">
        <property type="entry name" value="YbeY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00043">
        <property type="entry name" value="TIGR00043"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01306">
        <property type="entry name" value="UPF0054"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 7" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="5 7 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 7" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="7" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="6 7" id="KW-0862">Zinc</keyword>
    <feature type="binding site" evidence="7">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV58793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="161" mass="18213" checksum="783C93D583EBCAC2" modified="2019-10-16" version="1">MSDDLAVEINVQHEASFIDRPALESAVRLVAETYGICRGEVSIAIVDDDNMQRLNNQFLQHDYTTDCLSFVYDESEDSISGELILCADYAQREAAEFEWQPESELLLYAVHGMLHLMGMEDTTDEGRQAMRDEEREILLRLGIEGAKRHGLPTNSNPSEKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0L6</accession>
    <name>A0A518J0L6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RNA polymerase sigma factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_49080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sigma70_r4_2" evidence="1">
        <location>
            <begin position="169"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="242" mass="26890" checksum="7787F7EBF2F06446" modified="2019-10-16" version="1">MISIQHDLKSAACLQDHDRSSFSSTIKPAMDHEQTTLDVQRYLDELGNLDGSAPAEPIIRALIDRSVGRLQMLCEALLVRSYPRLMQPPLNLQSEEMLSAVVDRLIKAMQQVRPATVRQFFGLANQHMRWELNDLARRLDKHPADRELNAGLAMAPEPSASQLTPNAVRMLDAIDNLPDDEREVFGLVRIQGMTHTEAADLLDVSPKTIQRRLNRCMILLTASLGDLNPDTPPATEVGPAGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0P7</accession>
    <name>A0A518J0P7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Esterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_49000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000801">
        <property type="entry name" value="Esterase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00756">
        <property type="entry name" value="Esterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="251" mass="28332" checksum="CA356CDF1DBB7504" modified="2019-10-16" version="1">MGFVAAFTIAFHVLVSSGQVRVDAAELQERVVERTYSETLQYRCLINLPDAYQTDKSRRWPLILFLHGGGNPTPAELKASIRGLLGLPAVVVAPICPPSQYGDRYTNWDSMQLGEVAREVGKEFRIDENRRSVIGFSMGGSGAWELPSYEQDLFSKSVVIAGLCHPWSLRHYPKTQVWVFVGEEDYMRKEQQETVSSAKRFKVDVVETVWAGADHGGIFKNAMSYQRMLNWHVQDEDLRLEQQMPPGPAVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0U2</accession>
    <name>A0A518J0U2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transcriptional regulatory protein ZraR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">zraR_13</name>
        <name evidence="8" type="ORF">Mal33_49910</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002197">
        <property type="entry name" value="HTH_Fis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002078">
        <property type="entry name" value="Sigma_54_int"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025662">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025944">
        <property type="entry name" value="Sigma_54_int_dom_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02954">
        <property type="entry name" value="HTH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00158">
        <property type="entry name" value="Sigma54_activat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01590">
        <property type="entry name" value="HTHFIS"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00675">
        <property type="entry name" value="SIGMA54_INTERACT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00688">
        <property type="entry name" value="SIGMA54_INTERACT_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50045">
        <property type="entry name" value="SIGMA54_INTERACT_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Response regulatory" evidence="7">
        <location>
            <begin position="10"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma-54 factor interaction" evidence="6">
        <location>
            <begin position="150"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="5">
        <location>
            <position position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV58966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="448" mass="49788" checksum="11847AFC990E8C48" modified="2019-10-16" version="1">MTAMAKTALDILFVDDDSDFAAGCIRWFQKNGHRVAHTTRGQDGVAQCEKLDFDISVLDWNLPGLCGLELVQRIRDAAAETEIIILTGEGTIENAVESMRRGVFDFLSKPFPMAELERRCLGALERRKLRKENTQLREVIDRTKRPPATMIGRSEPIQKIFRLIDRIAPTDKPVLIEGESGTGKELVAQGIHQGSPRGNRPMVTVNCAALPEQLVESELFGHEQGSFTGATAAKPGLFEVADGSTLFIDEVGELPLALQPKLLRVLEDGSMRRIGSEKERRVDVRIVAATNRSLKDEVAEGRFREDLYYRINLLTVHLPPLRDRGDDVSVLIDHFLGNGPELEAEARTALLAYDWPGNIRQLVNTIERAKILADDLITIEDLPDEFQSLGSAGSAETPANEGSLMTLQREHIAEVLARENGNKSAAARILGVERRKLYRMMKQHGIEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0Z4</accession>
    <name>A0A518J0Z4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Sialidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_50000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011040">
        <property type="entry name" value="Sialidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036278">
        <property type="entry name" value="Sialidase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13088">
        <property type="entry name" value="BNR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50939">
        <property type="entry name" value="SSF50939"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sialidase" evidence="1">
        <location>
            <begin position="140"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="427" mass="47522" checksum="F35CFC36BB310491" modified="2019-10-16" version="1">MRSQPPKRFALVFAAVSVVLSSTEKLPAADAQPPCVTIVERELTDAVSPYYRAIYGDVAKDRLVSSSWQSDDNGKNWSPIRSHHALARGLTPGFRRNPTTSTLDPNRNCVLAIVNALDTPNLDPKINEPPIAQKTYYLRYRVSTDGGASWLCDDPIVGVGDYDAKHPFDDLWIGKNAIYVGDNGCAPIVTDSGRVLLPVQMTVLDDAGELYQPPRAHTYTEAVALVGTWTDKNRITWRMPTRVKGDPAKTVRGLIEPTIAEAPDGRILMVMRGSNSHDSTVASSKWFAVSNDEGETWSEPKRWAYDDGTSFYSPSSMSVLMRHSSGRVFWVGNITPENPKGNLPRFPLVIGEVDPQSLQLIRSSVVVVDQKNPEDANRGRLDLSHVHLMEDRETKEMILTYTRAYHAYRQREFALLRLALSSPEDAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J139</accession>
    <name>A0A518J139_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_50860</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023874">
        <property type="entry name" value="DNA_rSAM_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21180:SF9">
        <property type="entry name" value="PTHR21180:SF9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01102">
        <property type="entry name" value="Uncharacterised_Radical_SAM_Su"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="SSF47781"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03916">
        <property type="entry name" value="rSAM_link_UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV59061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="417" mass="46650" checksum="F671DE518EF39164" modified="2019-10-16" version="1">MDVRDKLTVLADAAKYDASCASSGSKTTRPGSTIGSTEGMGICHSYTPDGRCVSLLKILLTNYCIYDCQYCVNRISSDTPRARFTVDEVVSLTMEFYKRNYIEGLFLSSGIIQTSDYTMEQLISVAKKLRTEQRYGGYIHLKTIPNASQSLIEEAGLWADRLSVNIELPTEGDLYKLAPEKKKPQIEGAMAGIRNKIDETKQEQKAGFKPPRFTPAGQSTQMIVGATDTPDVEVLKTASQLYSLQNLRRVYYSAYSPIPHADARLPGQSPPLVREHRLYQADWLIRFYGFDASEIVAEADQNLSLDIDPKLAWALANRHYFPVDVNKASREELLRVPGIGARNVKRILNIRRFQSLDSGDMKKLRVAWNRAKFFVLTADHNPALLNLDKLDLRAKAKPKTKQLLLFDAASSALSGEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1A4</accession>
    <name>A0A518J1A4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Calcineurin-like phosphoesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_51460</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003993">
        <property type="term" value="F:acid phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039331">
        <property type="entry name" value="PPA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22953">
        <property type="entry name" value="PTHR22953"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022213886" evidence="1">
        <location>
            <begin position="25"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="domain" description="Metallophos" evidence="2">
        <location>
            <begin position="156"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV59120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="428" mass="46816" checksum="9E3A30B4776FC913" modified="2019-10-16" version="1" precursor="true">MVDRRQFIGSIPVSAMAISAIALARPAASQDAAAEDSPSDSLIASPPVVQNPRGDSFGVSIAVDQLATAWVEYGLDRDDLKFTAIASQHGLVSADDRALHVRVQHDQPFPVGQPIFYRVVVQPLAYKNAYVLQRGEPQATDVYALRLPDPGAKRVRVVSINDTHENLETIRQLHAQIEALDPDLLIWNGDTCNDFDASDQPAQIMLNPAKDRSMSWASTRPLVFSNGNHDVRGQRARETIDCFVGCPESSELPYNQALRIGPLALVTMDTGEDKPDRHPVFAGTAAYEPYRSRQATWLQQAVNQPEVRDAPFKIVACHIPLRGLPGQNDGTTLEGYASFSGFGAKLWMPTLVESGFQAVLSGHMHRDRLDPATEEMPILQFVGGGPTAEKATLTIIDAEQNAADPSMEIRITDLGGKVLHQQTWNGKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1N4</accession>
    <name>A0A518J1N4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">Replicative DNA helicase</fullName>
            <ecNumber evidence="3 11">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">dnaC_3</name>
        <name evidence="14" type="ORF">Mal33_52730</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the helicase family. DnaB subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="3 11"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990077">
        <property type="term" value="C:primosome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006269">
        <property type="term" value="P:DNA replication, synthesis of RNA primer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00984">
        <property type="entry name" value="DnaB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036185">
        <property type="entry name" value="DNA_heli_DnaB-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007692">
        <property type="entry name" value="DNA_helicase_DnaB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007694">
        <property type="entry name" value="DNA_helicase_DnaB-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007693">
        <property type="entry name" value="DNA_helicase_DnaB-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016136">
        <property type="entry name" value="DNA_helicase_N/primase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00772">
        <property type="entry name" value="DnaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03796">
        <property type="entry name" value="DnaB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48024">
        <property type="entry name" value="SSF48024"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00665">
        <property type="entry name" value="DnaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51199">
        <property type="entry name" value="SF4_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 11" id="KW-0235">DNA replication</keyword>
    <keyword evidence="10 11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8 11 14" id="KW-0347">Helicase</keyword>
    <keyword evidence="7 11 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0639">Primosome</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SF4 helicase" evidence="13">
        <location>
            <begin position="201"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU362085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="QDV59245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="486" mass="54617" checksum="E2FF71DB3AA65046" modified="2019-10-16" version="1">MIAEGNDDKFKGSRRDKKKPKSTASEILQRQPPFDLEAEMGVLGSILLLPECLDDLATLLRPDDFYDDANRILFTQLQEMHDMGEKIDVTLLVSRLKKAKQYDLMGGPAYLGRLSTSVANAAHAVYYAKIVNEKAIYRKLIESSTDILRDAYDQTQEARELVASAEQKVFAIMDGKQSNSVNSISDILHQAMDRIDARLRGEHTDGGCDTLYTDFDAMTGGLHNGELAILAARPSMGKTAFAMNIAENVSMQLRYPVLFLSLEMSGIELADRMLCSISRVSGHKLRNGTISSEERERLVEKANEIHSAPLFVDDSPSRTVSEIAAAGRRIKRRDGALGLIVIDYLQLIEPDNSRDPRQEQVAKIARRLKGMARELEVPVLCLSQLNRQSEEGKDHRPKLSHLRESGAIEQDADIVMFVHREEYYHRGEDKEQYAGQAEIIIAKQRNGPVGDVELTWEGAFTRFHNKAPERHSEFDQYAEFSGPTDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J242</accession>
    <name>A0A518J242_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Membrane dipeptidase (Peptidase family M19)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_54310</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070573">
        <property type="term" value="F:metallodipeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008257">
        <property type="entry name" value="Pept_M19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10443">
        <property type="entry name" value="PTHR10443"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01244">
        <property type="entry name" value="Peptidase_M19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51365">
        <property type="entry name" value="RENAL_DIPEPTIDASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="441" mass="48391" checksum="7A8ACE77E4C73DB2" modified="2019-10-16" version="1">MLHRRQLLGSLGTAALLTAGLRNTALSADDASDPVAELSTRLNPNIQAAREAGLKILKPSAAELDRGLRLHAESIVFDSYGFSPRAAVDGDAIAAAIEAGASHDQVKDMREEMSMTRYVSDPVEQQEYRDAWRASGVTCVFQNAGEEGQDPLRLMRRLSRFTYATDLMRGFVSKAAVPADVETAKREGRHCLYLTGNGVPLRQQWESIPDELRYMQVFYHLGIRMMHLTYQRRNMIGDGCGEKSDAGLSDFGHAAIAEMNRLGIIPDCAHSGWKTSLEAAQSSSRPMVASHSTCGAIHPHIRSKPDEVIRAIVDTGGYIGICCIPRYLRGSGDITAMLDHIDYAVKKFGPDAVAIGTDVAYNSQNAGRELAKLPRMSKQYQPFRSLWPADDYKTLPGAAQSIAWTNWPLFTVGLVQRGHSDEVIRKIIGGNVMRVINASMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ILX2</accession>
    <name>A0A518ILX2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_00220</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="373" mass="40457" checksum="15060BECD926F9D8" modified="2019-10-16" version="1">MTCTRVPTVQYEAIVSASKKNASTGFVFLQLSDSTNNLKSLIHRLRSALDTRIVVVGNATTGRQVIEIIRAGADDFVDEKDDLRRELGLLLKRAAPSGMPNQRKSELITVTSSCGGCGASSLAVNIAAQYAHKYGECGLVDLQMHGGDLATLLRLTPRHTISKMLANNHPLAPEMVQQALTKHETGISLLAGADPLSNLPNSSPETIRGIVRSMTTNFQRVVVELEDISHREQLAALSDSDQVVLTFRLHFPALARAHRFFESIERFGVDPDKVRIVASQVGQPDEVPIGQAEKIFGRKIDACITNDVSPMNRAVNLGIPVVLDSPKSQCSRDYMALVQLLDGETPVPANTRWNVGALFKSKFGSSQPAPALS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ILZ0</accession>
    <name>A0A518ILZ0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Linear gramicidin synthase subunit D</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">lgrD</name>
        <name evidence="6" type="ORF">Mal33_00530</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="6 7">Mal33</strain>
        </source>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="project" value="UniProt"/>
    </dbReference>
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        <property type="project" value="UniProt"/>
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    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_domain"/>
    </dbReference>
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        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="Condensatn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020802">
        <property type="entry name" value="PKS_thioesterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001031">
        <property type="entry name" value="Thioesterase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00824">
        <property type="entry name" value="PKS_TE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
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        <location>
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            <end position="635"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="5">
        <location>
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            <end position="1715"/>
        </location>
    </feature>
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        </location>
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        <location>
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            <end position="562"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="3">
        <location>
            <position position="594"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="3">
        <location>
            <position position="1675"/>
        </location>
    </feature>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV54112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1995" mass="219361" checksum="1BE9D43E5AF46B9D" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ILZ9</accession>
    <name>A0A518ILZ9_9BACT</name>
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        <submittedName>
            <fullName evidence="6">Polysaccharide biosynthesis protein</fullName>
        </submittedName>
    </protein>
    <gene>
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    </gene>
    <organism evidence="6 7">
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        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    </dbReference>
    <dbReference type="Pfam" id="PF01943">
        <property type="entry name" value="Polysacc_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="53"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
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            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
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            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
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        </location>
    </feature>
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        </location>
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        </location>
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    <feature type="transmembrane region" description="Helical" evidence="5">
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            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
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        </location>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
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        </location>
    </feature>
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    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="QDV54107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="474" mass="50590" checksum="DA7936E5AD4570F0" modified="2019-10-16" version="1">MEAAEGSGVQRTGKRLFRESLWVVGGRLLGIGTAIAINVVLARVLPPSDVGVFFLLASILTFAGYVAMFGLNAAMVRFVSERIGVEDVRGAEAALRQGAKLAVASIVIGSLLCFVFLYFAGEQVFGVDNLSVLAPLVALSVLGSATIQLCASLLRSFHDSRLSILLTGQFGGPLCNLLFIGLTVGSCLLFAPTLEQVMIFCAGSLCLLTPFAIFCVHRIARTRLSQIEQSDQPSHVLPMATLLLVCLPLMLTQGLSYITGQADIWIGGAIVDHEELALYAASRRLMLLIGMPMQLVNLTVIASIAELRAQGRLQDLQRILRSAATLAAVAALLVCVPIMIFPGEIAAFIFGPYYAGGATVLRILCIGQVVFVSVGAAELTLMMSGQHMKALSINTFTSIALFASGVFMTHHWGIVGLAIAWTAIVSLQCIGFCLMARWSVGVWTVMEVRVLRAGREMLATVTSKLGKARNNNAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IM11</accession>
    <name>A0A518IM11_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Chondramide synthase cmdD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">cmdD</name>
        <name evidence="6" type="ORF">Mal33_00760</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043604">
        <property type="term" value="P:amide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901566">
        <property type="term" value="P:organonitrogen compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
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        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="Condensatn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
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    <dbReference type="InterPro" id="IPR020802">
        <property type="entry name" value="PKS_thioesterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001031">
        <property type="entry name" value="Thioesterase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00975">
        <property type="entry name" value="Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PKS_TE"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
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    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
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        <location>
            <begin position="1421"/>
            <end position="1496"/>
        </location>
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    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="25"/>
            <end position="48"/>
        </location>
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        <location>
            <begin position="1400"/>
            <end position="1422"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="3">
        <location>
            <position position="1456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
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    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV54130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1771" mass="195147" checksum="8AADB8BECAC8681B" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IM15</accession>
    <name>A0A518IM15_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">dTDP-glucose 4,6-dehydratase</fullName>
            <ecNumber evidence="2">4.2.1.46</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rfbB_1</name>
        <name evidence="2" type="ORF">Mal33_00650</name>
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        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="4"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="336" mass="37650" checksum="1564536278C88C9F" modified="2019-10-16" version="1">MKYLITGAAGFIGFHLSQYLLARDHNVVGIDNLNDYYSVDLKNSRLSQLKSHPNFEFQQISLEDTGPMTELFQSHQFDRVVNLAAQAGVRYSIENPAAYIQSNINGFLNILEGCRHTQVPHLTYASSSSVYGANTKMPFSVHHNVDHPVSLYAATKKSNELMAHTYSHLYGLPTTGLRFFTVYGPWGRPDMALFLFTKAILEGRPIDVFNHGRMQRDFTYIDDIVEGVARTADQIAAPNPEWSSDKPDPGTSKAPYRIYNIGNNNPVELNQFIGAIETALGRTAEKNFMDMQPGDVPATYADVQALVDAVGFQPKTSIETGISRFVDWYRDYYQVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IM22</accession>
    <name>A0A518IM22_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_00880</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017460">
        <property type="entry name" value="CHP03000_planctomycetes"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03000">
        <property type="entry name" value="plancto_dom_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021911767" evidence="1">
        <location>
            <begin position="26"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="403" mass="41514" checksum="E5FC9024DD5B0130" modified="2019-10-16" version="1" precursor="true">MRRIHVIPVAIAAVAMTFTGEAAHAGWGSFGSYGSYGSHGSSGSYGSSGGYRSYGSSGASSGSYGSYSVSYSSYGSSGASYGSSGSSGDSSGHFGILKRIKARHQAWRAARASSGGSSGYASSGSSGYSVSSYASSGGSYGSYRAYSSYGSSGGSSGHQSSGGSSGSYSSSYYSTPVESYSTPMYESAPIYSEPAAEAAEGESIIETPVEGASYQTQSASSTSEALLTMEVPADADVYVNGTKTRSTGAHRQFVSRGLTPGYAYSYDVRIEHTVNGELVTESKVVRLHGGETRSLVYSAPAVEAPAYVAAPEAESDVVETVLTVNVPADAKVTLAGNATDADGTTRTFRTKQLQAGQVWSDYTVTVAIQRDGRTLTEEKTISLSAGSTPELTFDFADETVAMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IM86</accession>
    <name>A0A518IM86_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Pheromone autoinducer 2 transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Mal33_01590</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002549">
        <property type="entry name" value="AI-2E-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21716">
        <property type="entry name" value="PTHR21716"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01594">
        <property type="entry name" value="AI-2E_transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="42"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="71"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="162"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="221"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="249"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="286"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="316"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="127"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="372"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="375"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV54210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="409" mass="43451" checksum="96E1FE992BEA4114" modified="2019-10-16" version="1">MNEQSTDPADSELLASRNGLLSVRVCAIMLILYALYYARSLAIPVVTAVVLYLTLRPIIRHARRIGIPSAVSAAGIIVGIALTLGLGTYLVIEPAKATIAEAPQHLGVVKEKLSFITDRLKEVDKATEELAEAEEESTGGSQEEQPVPVEIKQPTWTSGWSYLSGTGNLVSFLTICIAMLYFLLANGDSLLRSIMHSLPDFTARRKLVEVIQKVQEGLGSYLAKISTINACLGLSVGIAMWGLGMPSPVLWGAMAFAFNFIPILGAIAGGAIVFVVALVSFEATYYAFLVAATFLTLTSLEGQFITPAILGRSMSMSPVLVFLSIVVWGWMWGVMGVFLSVPMLIAARMACEGYEGLGPLAMILGAEVPESKSASASGRGGSDSTADNPPAPQTYLNIVQPSVAGSENQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IM96</accession>
    <name>A0A518IM96_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Rho_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_01560</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006353">
        <property type="term" value="P:DNA-templated transcription, termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011112">
        <property type="entry name" value="Rho_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036269">
        <property type="entry name" value="Rho_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07498">
        <property type="entry name" value="Rho_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00959">
        <property type="entry name" value="Rho_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68912">
        <property type="entry name" value="SSF68912"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rho_N" evidence="2">
        <location>
            <begin position="61"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="99" mass="11478" checksum="DE22B5AD927B7CCF" modified="2019-10-16" version="1">MPRWSDKDQRQYKHIKDSQLDSGRSEERAEEVAARAVNKQRREEGRTPNKTTQGTGNPHTPLEDRTVDELRNIASNLNISGRSKMRKHELIDAIRSRRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMA0</accession>
    <name>A0A518IMA0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Xylose operon regulatory protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">xylR_1</name>
        <name evidence="2" type="ORF">Mal33_01600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="1">
        <location>
            <begin position="304"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="407" mass="46097" checksum="6828398D8A682385" modified="2019-10-16" version="1">MDPRLDHCSADLRNPTEAMKIVQQRRSVALLVETSNAYARGVLAGIIDYIQQHQRWSLVLPEQERGARPPDWLQRWQGDGIIARIETDEIAQAIRRTQCPVVDVSAARHLPGVPWVETDDDAIARIAVEHLVERGFRHLAFCGDSGFNWSQWRQQAFEQYVQQAGGTYYQYDSIPRHDPEYSWNSERARLAQWVEQLPHPIGIFACYDIKAQQLLDVCRELNIAVPEQIAVLGVDNDRLLCDLADPPLSSVSCNTRRTGYEAAAMLDRMMAGDTIGAEKVLLEPLGIQTRQSTDILATDDPDVAAAVRFIREHACDGIKVVDVLNEVPVSRRVLEKRFVKILGRSPHEEITRLRIDRVKQLLVQTDLSLAEIARRTGYRHDEYLSVAFKNVVGVQPSKYRQSAKTSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMC6</accession>
    <name>A0A518IMC6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_02020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022201305" evidence="1">
        <location>
            <begin position="23"/>
            <end position="789"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="789" mass="89133" checksum="702CCAF0299F424F" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMQ9</accession>
    <name>A0A518IMQ9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Pyrimidine-specific ribonucleoside hydrolase RihA</fullName>
            <ecNumber evidence="5">3.2.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rihA</name>
        <name evidence="5" type="ORF">Mal33_03190</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.2.-.-" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045437">
        <property type="term" value="F:uridine nucleosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901564">
        <property type="term" value="P:organonitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.245.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015910">
        <property type="entry name" value="I/U_nuclsd_hydro_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001910">
        <property type="entry name" value="Inosine/uridine_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023186">
        <property type="entry name" value="IUNH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036452">
        <property type="entry name" value="Ribo_hydro-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12304">
        <property type="entry name" value="PTHR12304"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01156">
        <property type="entry name" value="IU_nuc_hydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53590">
        <property type="entry name" value="SSF53590"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01247">
        <property type="entry name" value="IUNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="IU_nuc_hydro" evidence="4">
        <location>
            <begin position="65"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV54365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="373" mass="40599" checksum="1307B8621CD759AB" modified="2019-10-16" version="1">MQGCRVAASERAGGQYNDSGDRLGPPRRQSSLAEGRLCVSRSVETKSPFRHLADNRTIAPMARKVIIDCDPGIDDAIALTMALFDPRLEVLAVTATAGTVDADQATTNVQGLIQQLDPPKYPRIGVASPCEGAAVSNDIVLHGSDGLAGCNYEPSDRQHRHLSEKIISELLRQHPNQVSLICLGPLTNVARAFQREPGLESLVDRLVVSGGAVACPGNISPVAEMNMYFDPTAARSVIESATTKSLVPLDVTDQVEFSIELIENLPSKQTRAGQLLHKLLLFAFRSYVQNLGRETISLYDPVALLGFLEPELFTWEDMAIDIETRGELTRGQTVCDARRHREWSLNAEVARSIDTTAAVNQIVRGLRFAGQCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMV5</accession>
    <name>A0A518IMV5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Peptidase family M48</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Mal33_03570</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the peptidase M48 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001915">
        <property type="entry name" value="Peptidase_M48"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01435">
        <property type="entry name" value="Peptidase_M48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1 6" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="76"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="100"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="163"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="193"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="298"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="326"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M48" evidence="8">
        <location>
            <begin position="254"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV54403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="435" mass="47557" checksum="B08C6CDB3487BEDC" modified="2019-10-16" version="1">MPVYWFALLISVLLSASSTDMLTLPSPFVTAFGMVMLWGVIAKGFAILNAQRVLRQQASFDQAARKLSRQLNCLRWLWLPLGAVGLTACGFSQAVEDSPIGASMALGAMGMLIPSLAAVSSTWLAERQFSDWVGEAEPVQNESDSPSRFPTLHAVMESLRLQAAWILLPVLFVFAVIDVVNFGFVGADSQHRWVGGAAGLLCLPFFLPMLIRFIWNTRRCEHDPQSAWLVDVVRAAGLRHFRIRRWETEGRICSALVAGFIPGFRMLLLSDALLDRLDRKSTTMVVLHELAHVRRWHIALRMLTLVPTWGIVGFIGSHFAGAPLQQGAVVAAGLLLTLLALRWVSHATELDADRYACSLAAQIAATDSGNRLQGAVPASEVDAAYVLASALVDVCSDNPKACRASWMHPSLATRVDRLHRVANPAVSQQSSLQQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMY0</accession>
    <name>A0A518IMY0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_03850</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="507" mass="55599" checksum="9C38615E5EF515FC" modified="2019-10-16" version="1">MSATYWQIPLGHLDVTVWDPNLDIDSDNNNGTNYPDNSDWEEYLEDNGYGLGKFVFPTATYYTPLRLRLTPGLNPLIEDVQVRLNFPGAGQSGVLHMWNTYAADPARVDDDVPDGGNRLIPGSVYSLSDLNYDSGNGAVTIYIDAISTFPNHDTKQHVINNGKSDDRIRATLVDPGNGDLAFDEVKYMIVNEDTFYPHLNQKVVLRSAMASEGVYDQADLPQYALKRLTSDELDALFGEGSDILDLIGGTTSVPGLETAIYRDHVTGQYVLAFAGTNDAEDWIDNLRQNMTVPAAQYEAAMRIADAMNRLEVFLESGMYFTGHSLGGGLASAGAVVTGQNAYTFNAAGLRRDTLMAWDPVAGAHTDQEIYPGSLYNYDNASWYVDAYYLDWDILSFIQDQIPAVDRVNILATFFPTLSSATVDLFQPAIGNRFVMDGPLDAEMLAYTLFAGVLTPSKVLNAILAGSVPLILMSAAHTTDYYHYGLMVDESTGWDIFGVPLPLDTLPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IN18</accession>
    <name>A0A518IN18_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Chemotaxis protein CheY</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">cheY_1</name>
        <name evidence="3" type="ORF">Mal33_04320</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="8"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="140" mass="15737" checksum="F8C686854913DD0E" modified="2019-10-16" version="1">MSQMTSKQILVAEDDPVFRRVIVFALKQVGFTVDSVSDGEQAQHQLHAGEYDMLITDHQMPLCSGLDLIQRLRESPRFAHLPVVLCTARGLELDKDHLQNRLQLAGIMHKPFSPRLLAERVRTLLATHEAQLLTTNSTIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IN24</accession>
    <name>A0A518IN24_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 8 9">Xylose isomerase</fullName>
            <ecNumber evidence="2 8 9">5.3.1.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8 11" type="primary">xylA</name>
        <name evidence="11" type="ORF">Mal33_04430</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7 8 9">
            <text>alpha-D-xylose = alpha-D-xylulofuranose</text>
            <dbReference type="Rhea" id="RHEA:22816"/>
            <dbReference type="ChEBI" id="CHEBI:28518"/>
            <dbReference type="ChEBI" id="CHEBI:188998"/>
            <dbReference type="EC" id="5.3.1.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="8">Binds 2 magnesium ions per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8 10">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8 10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 8 9">Belongs to the xylose isomerase family.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.5" evidence="2 8 9"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009045">
        <property type="term" value="F:xylose isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042732">
        <property type="term" value="P:D-xylose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00455">
        <property type="entry name" value="Xylose_isom_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013452">
        <property type="entry name" value="Xylose_isom_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001998">
        <property type="entry name" value="Xylose_isomerase"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00688">
        <property type="entry name" value="XYLOSISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="SSF51658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02630">
        <property type="entry name" value="xylose_isom_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51415">
        <property type="entry name" value="XYLOSE_ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8 9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 8 9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8 9" id="KW-0859">Xylose metabolism</keyword>
    <feature type="active site" evidence="8">
        <location>
            <position position="127"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="130"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="258"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="294"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="297"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="322"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="333"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="335"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="365"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00033659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QDV54489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="466" mass="52181" checksum="70522CC00FBB7FB6" modified="2019-10-16" version="1">MQDHANRTEGPAPESRLLQLLYYSRAAMTAFPEIGKIAYEGPESDNPLAFRWYNPDEVVEGKTMKDHLRFSVVYWHTFRGTGSDPFGPGTAVRPWEDGTDSVENACNRARVAFEFIEKLGAPFYAFHDRDIAPEGASLAETNRNLDAVVAVLKEEQQRTGIKLLWGTANMFSNPRFMHGAATSCNADVVAYAGAQVKKALEVTKELGGENYVFWGGREGYQNLYNTDIRRELDHLGSFFHMAVDYAKEIGFDGPFLIEPKPKEPTKHQYDSDAAACINFLRAYELTDHFKLNIETNHATLAGHSMMHELDYAGAQDMIGSIDANTGDMLLGWDTDQFPTDYYLTSQTMLMLLKYGGLTTGGVNFDAKVRRESFEPIDLFYAHIGGMDAFARGLKIAAAIRADKALENFVSERYASFDSGIGQKIEQGKTSLKELEAYMLEKGEADANQSGRQEMLENVFNRYIDRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IN39</accession>
    <name>A0A518IN39_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_04540</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005625">
        <property type="entry name" value="PepSY-ass_TM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03929">
        <property type="entry name" value="PepSY_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="48"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="280"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="312"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="337"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="360" mass="40097" checksum="5026B735471DB3CF" modified="2019-10-16" version="1">MSSSTDSATPNSPDDLDNANGESARRLPKKKTRAEKLGRSTVMLLRRIHLYSGIFMFPWVLMYGFSGWMFNHPRMFTADEVTTYHAADLDDGLLTDLTSAQQTAIAVVEQINLQTSESQGPELRITDDRRPLFSGHLEYNVNTPTAKHQLAVNPVTGDGEVRTTLVDAEADDAADDKPDPLAEVYRVEIEPNVSADIQRQIPEVLDQLGLPSNRASLGYRKLSVVFSAEADGIPCIVSYNLADGSVNSVRDDDRPQLTKKAFLQRMHLGRIYTPVMEIRWLWALLVDAMFVSMVFWGCSGLLMWWQIKRTRWLGMGLLATSILFATFVGLGMHDQMTSTGPPKKIPAEKTTDTKASDQSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INK1</accession>
    <name>A0A518INK1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_06210</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="340"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="361" mass="40835" checksum="EB65D941C4BBAEB8" modified="2019-10-16" version="1">MTPTAPPKIRQPARPELMSIHSLFGRLAVLTIFISLSASELHAEDESLTQEVIQGLRKWRETISSLRIDYVYRNPNEVKAEHPDWSEVEVEGCYFVGRWIWKDDGSVYSRLSPYRNGKDVGNHMVEGANFRTNEIYQANFGVEEDGSQYLKSLSVKPMRSGSAITGNPMPLMRLWQSGRWFDDAIEAGQYVATNQPNTTLIQIKTLSTANPEVTLVDRQQQYLVQTIHHEAIGSKFSVEEYQSLENGTLFPNNGKYFAGNATPRDQVIEWEIVAIGINEQHDSGLFIPPETGQKTYIHDSTPARKYRRRDLPPSQVAAMADQIEMKDGPIRAIVPRGLQIQYMLLGLASICLVLGVWLARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INT4</accession>
    <name>A0A518INT4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Transcriptional repressor NrdR</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 10" type="primary">nrdR</name>
        <name evidence="10" type="ORF">Mal33_07110</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 1 zinc ion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the NrdR family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00440">
        <property type="entry name" value="NrdR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005144">
        <property type="entry name" value="ATP-cone_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003796">
        <property type="entry name" value="RNR_NrdR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30455">
        <property type="entry name" value="PTHR30455"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03477">
        <property type="entry name" value="ATP-cone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00244">
        <property type="entry name" value="TIGR00244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51161">
        <property type="entry name" value="ATP_CONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0678">Repressor</keyword>
    <keyword evidence="6 7" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 7" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="ATP-cone" evidence="9">
        <location>
            <begin position="49"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="zinc finger region" evidence="7">
        <location>
            <begin position="3"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV54751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="155" mass="17972" checksum="13C89B286FB7D50F" modified="2019-10-16" version="1">MRCPFCQHDNDRVLDTRANEDGFSVRRRRCCNNCRRRFTTYERVEEIGIRVIKKDLVREPLNREKIRAGIETACWKRPPSRERIDSVVEGIVAEIHGQFEDEVSSRQVGEIVMKHLAPLDAVAFVRFASVYQEFDSLNDFVNVLSGRQQASKASE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INY2</accession>
    <name>A0A518INY2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">3-phosphoshikimate 1-carboxyvinyltransferase</fullName>
            <ecNumber evidence="7">2.5.1.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">5-enolpyruvylshikimate-3-phosphate synthase</fullName>
            <shortName evidence="7">EPSP synthase</shortName>
            <shortName evidence="7">EPSPS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 10" type="primary">aroA</name>
        <name evidence="10" type="ORF">Mal33_07640</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>3-phosphoshikimate + phosphoenolpyruvate = 5-O-(1-carboxyvinyl)-3-phosphoshikimate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:21256"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57701"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:145989"/>
            <dbReference type="EC" id="2.5.1.19"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 6/7.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the EPSP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.19" evidence="7"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00089"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003866">
        <property type="term" value="F:3-phosphoshikimate 1-carboxyvinyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01556">
        <property type="entry name" value="EPSP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.65.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00210">
        <property type="entry name" value="EPSP_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001986">
        <property type="entry name" value="Enolpyruvate_Tfrase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036968">
        <property type="entry name" value="Enolpyruvate_Tfrase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006264">
        <property type="entry name" value="EPSP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023193">
        <property type="entry name" value="EPSP_synthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013792">
        <property type="entry name" value="RNA3'P_cycl/enolpyr_Trfase_a/b"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00275">
        <property type="entry name" value="EPSP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000505">
        <property type="entry name" value="EPSPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55205">
        <property type="entry name" value="SSF55205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01356">
        <property type="entry name" value="aroA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00104">
        <property type="entry name" value="EPSP_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00885">
        <property type="entry name" value="EPSP_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 7" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="EPSP_synthase" evidence="9">
        <location>
            <begin position="11"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Shikimate-3-phosphate binding" evidence="7">
        <location>
            <begin position="27"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphoenolpyruvate" evidence="7">
        <location>
            <begin position="98"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Shikimate-3-phosphate binding" evidence="7">
        <location>
            <begin position="174"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="318"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="346"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="32"/>
        </location>
        <ligand>
            <name>3-phosphoshikimate</name>
            <dbReference type="ChEBI" id="CHEBI:145989"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="202"/>
        </location>
        <ligand>
            <name>3-phosphoshikimate</name>
            <dbReference type="ChEBI" id="CHEBI:145989"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="345"/>
        </location>
        <ligand>
            <name>3-phosphoshikimate</name>
            <dbReference type="ChEBI" id="CHEBI:145989"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="349"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="390"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="415"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV54799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="437" mass="46014" checksum="AA5DB5D5E5B3D4C4" modified="2019-10-16" version="1">MSESSQTTVEVQPSGQVNGSIRPPGSKSLTNRALICAALARGTTHLTGVLRSEDTEVMIDALRQLDVRIDLSPDGRVAAVSGIGGSDASHKAEVYVANSGTTIRFLTAMLSALGGNYRLHGIDRMHQRPIGDLLTAINQTGGGASSEQGDGCPPVRIDSQGWQGGKVTVGGNVSSQYLSGIMMAAPLSRSPLEIHVEGELVSRPYVDMTLAVIRSFGVDVTETTPGVFAVQAPCVYQAIEYDIEPDASAASYFWAAAAVSGGTVKVEGLTRAALQGDVGFVDCLAKMGCTVTDAPDGITVAAGGPLRGIDVDMNQISDTVQTLSVVALFAEGPTTIHGVAHNRFKETDRITDLATELRKLGATIEEFDDGLRITPGPLRAATLETYNDHRMAMSFAVAGLRAPGIQIKNPACTAKTYPEYFADLQRLTGQSHHWTAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INZ8</accession>
    <name>A0A518INZ8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">GtrA-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Mal33_07880</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GtrA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000271">
        <property type="term" value="P:polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007267">
        <property type="entry name" value="GtrA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04138">
        <property type="entry name" value="GtrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="14"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="78"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="105"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="GtrA" evidence="7">
        <location>
            <begin position="16"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV54823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="140" mass="15269" checksum="ED3F2EA09A82E9C8" modified="2019-10-16" version="1">MTRPGFRAAGASRAIRFMILSGVSFLGNLGITHALTQHAAWPAELAFAASLVIIFFVNFACCRWFVFQASEQPIATQLASFLTATICFRGLEYVAFLGLHSLLGIHYLIATATVLIAGFAAKFLFYNRFIFGRPSAATQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPE4</accession>
    <name>A0A518IPE4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_09250</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="110"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="162"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="205"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="267"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="304"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="342"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="369"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="397"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="530" mass="56128" checksum="32B292C193282FBD" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPP5</accession>
    <name>A0A518IPP5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lipoprotein NlpI</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_10150</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013105">
        <property type="entry name" value="TPR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07719">
        <property type="entry name" value="TPR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="38"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="72"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="451" mass="50644" checksum="6A5F9F1FCADB7A54" modified="2019-10-16" version="1">MPTVQEVLNQGWTIQQQGNYAAAEKIYRHVLQQAPGSAAGWCYLGIALYDQRRFEESEAAYRKALSLQNHFPIAWNNLGNTLRMLGQVEQADQAFETSLQQDPKYLSPLKNRGTLWVWTGQIDRGLAAFEASLEVAPNDPELHRNLGVIHLLKGDFRRGWDEYRWRWKMPGFVRPNVSQPVWNGSDPQGKTFLLYSEQGLGDAIHFVRMAIALKERGARTIVQAAPKLIPLLSTCRGIDQLIPEGMLPGNFDFHCSFIDAADRLGIDVESIPDVGPYLGPSENLQAYWANWLAQIPGKKKVGICWQGNPQHQADIFRSIPLQAFEPLASIPDVQLVCLQHGFGIQQLDQVDFADQIVRLPANLDQSSGAFMDTAAIMKGLDLVVTSDTSVAHLAGALGVPVWVGLPKVPDWRWLLQGDSSPWYPSMRLFRQPEMKNWAAVMAEIKLHLERF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPR8</accession>
    <name>A0A518IPR8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glutathione hydrolase proenzyme</fullName>
            <ecNumber evidence="4">2.3.2.2</ecNumber>
            <ecNumber evidence="4">3.4.19.13</ecNumber>
        </recommendedName>
        <component>
            <recommendedName>
                <fullName evidence="4">Glutathione hydrolase large chain</fullName>
            </recommendedName>
        </component>
        <component>
            <recommendedName>
                <fullName evidence="4">Glutathione hydrolase small chain</fullName>
            </recommendedName>
        </component>
    </protein>
    <gene>
        <name evidence="6" type="primary">ggt</name>
        <name evidence="6" type="ORF">Mal33_10640</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2 4">
            <text>an S-substituted glutathione + H2O = an S-substituted L-cysteinylglycine + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:59468"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:90779"/>
            <dbReference type="ChEBI" id="CHEBI:143103"/>
            <dbReference type="EC" id="3.4.19.13"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>an alpha-amino acid + an N-terminal (5-L-glutamyl)-[peptide] = 5-L-glutamyl amino acid + N-terminal L-alpha-aminoacyl-[peptide]</text>
            <dbReference type="Rhea" id="RHEA:23904"/>
            <dbReference type="Rhea" id="RHEA-COMP:9780"/>
            <dbReference type="Rhea" id="RHEA-COMP:9795"/>
            <dbReference type="ChEBI" id="CHEBI:77644"/>
            <dbReference type="ChEBI" id="CHEBI:78597"/>
            <dbReference type="ChEBI" id="CHEBI:78599"/>
            <dbReference type="ChEBI" id="CHEBI:78608"/>
            <dbReference type="EC" id="2.3.2.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 4">
            <text>glutathione + H2O = L-cysteinylglycine + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:28807"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:61694"/>
            <dbReference type="EC" id="3.4.19.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Sulfur metabolism; glutathione metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.</text>
    </comment>
    <comment type="PTM">
        <text evidence="4">Cleaved by autocatalysis into a large and a small subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the gamma-glutamyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.2" evidence="4"/>
    <dbReference type="EC" id="3.4.19.13" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00204"/>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036374">
        <property type="term" value="F:glutathione hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102953">
        <property type="term" value="F:hypoglycin A gamma-glutamyl transpeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0103068">
        <property type="term" value="F:leukotriene C4 gamma-glutamyl transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006750">
        <property type="term" value="P:glutathione biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006751">
        <property type="term" value="P:glutathione catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="GGT_lsub_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000101">
        <property type="entry name" value="GGT_peptidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043137">
        <property type="entry name" value="GGT_ssub"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="g_glut_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-0317">Glutathione biosynthesis</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0865">Zymogen</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="595"/>
            <end position="614"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU368036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV55095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="614" mass="66228" checksum="1F298EFCFEBA63E2" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPW7</accession>
    <name>A0A518IPW7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ADP-ribose pyrophosphatase</fullName>
            <ecNumber evidence="3">3.6.1.13</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">nudF</name>
        <name evidence="3" type="ORF">Mal33_10920</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.6.1.13" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047631">
        <property type="term" value="F:ADP-ribose diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
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        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="2">
        <location>
            <begin position="32"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="174" mass="19469" checksum="E791AF59A1C07673" modified="2019-10-16" version="1">MSDRIVFEGIRFNVHEIDVPTADGSPIKRHVARHPGAVVIAPLLDNDRVVLIQNTRATVGKTLMELPAGTREPNEAAEVTAARELIEETGYRAGKLTRALQFYASPGITDELMHLFIAEDLTEGDHAREAGEAIVNRITTWAEIDAMIDRGEFEDGKTLTGLLWVRRWLDRQNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQ00</accession>
    <name>A0A518IQ00_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Single-stranded-DNA-specific exonuclease RecJ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">recJ</name>
        <name evidence="9" type="ORF">Mal33_11450</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RecJ family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008409">
        <property type="term" value="F:5'-3' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001667">
        <property type="entry name" value="DDH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038763">
        <property type="entry name" value="DHH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003156">
        <property type="entry name" value="DHHA1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004610">
        <property type="entry name" value="RecJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041122">
        <property type="entry name" value="RecJ_OB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01368">
        <property type="entry name" value="DHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02272">
        <property type="entry name" value="DHHA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17768">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00644">
        <property type="entry name" value="recJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DHH" evidence="6">
        <location>
            <begin position="80"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="DHHA1" evidence="7">
        <location>
            <begin position="347"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="domain" description="RecJ_OB" evidence="8">
        <location>
            <begin position="465"/>
            <end position="573"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF17768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV55175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="583" mass="63497" checksum="D5955564E54CF1CB" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQ52</accession>
    <name>A0A518IQ52_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_11960</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="101"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="243"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="272" mass="30850" checksum="49B4A13411BCA60F" modified="2019-10-16" version="1">MLHKRTRRTIALSLTATAVLIAAIATWLIRQRLGHASMATGWTLLASVGLLMLLGLRKKLVMLPILPVRVWTQFHIYTGLFALAIYLMHVPVVIASGFFESTLSLLFLSVAGSGLYGVWISRRGAKRLTAIAGEYRFDRFGWHRRTIADRASEIVTEVGQTGDVPVIAKFYRERLQQYFSTRPSLAYVLVPTSHRKRRLLTELGELDRYFASNVKQAAGRLAALIRNRDDLDYHYATQLRMRMWLAIHIALTVAMLVFIVVHVLMVLRFQGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQI0</accession>
    <name>A0A518IQI0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_13130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="50" mass="5735" checksum="FED79A149F6AC23A" modified="2019-10-16" version="1">MNWLSHADSERGRRYDHLGRDESRMEMENGICSQESAGAATDDKHPWDGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQM3</accession>
    <name>A0A518IQM3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ECF RNA polymerase sigma factor SigE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">sigE_3</name>
        <name evidence="4" type="ORF">Mal33_13630</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="2">
        <location>
            <begin position="33"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="3">
        <location>
            <begin position="124"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV55392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="185" mass="21285" checksum="4E6CFBFA5317D296" modified="2019-10-16" version="1">MEHRSECNDREPIDDATVRAGAGGDRAALRQIYEATADRVFRLMVRMVGQQDADDLTQQTFVRAFMKLDQFSGESKFETWLYRLATNEALQHLRREKHRRTKQLIVEPAMQATDHLVHDERVAMLRQAMDQLDPELRAIFTLKEESGLSYQEIANTLGIPEGTVGSRLNRARRELRRLFAGDVKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQM9</accession>
    <name>A0A518IQM9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ion channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_13720</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013099">
        <property type="entry name" value="K_chnl_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07885">
        <property type="entry name" value="Ion_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="104"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="132"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="domain" description="Ion_trans_2" evidence="2">
        <location>
            <begin position="83"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="343" mass="38094" checksum="AD28DF0CE9941477" modified="2019-10-16" version="1">MNWFLTAGGFLMTCLGVWETFMAVLHPRATVGPITAGINRGFHLLVRTRMFAHPRVLVYCGPALIVTQVLCWATLLLIGISLVVWPQLGTGITATGSTPTDTGFASAVYYAGFTITTLGVGDLVPRTPAMQFLTITAAGLGFSFFTLVLAYVISVYSTLARRNQFANEIEYRTGRTGDSLGYLRAYLTESDPSLVNQDLYTMSSNMADLLESHHFYPVLHYFRFSEPRYAMSRMLRFCLEVSSMMRAARQVDTAKPAASAEAVDRLWHASMQMLEETKRHFVICHSTHDVPGPRLAIEISRSIGDSDDLLDKLKGAFVDQQSEWLHDLNALAVCTRSEPLKES</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQP4</accession>
    <name>A0A518IQP4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Silver exporting P-type ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">silP_1</name>
        <name evidence="9" type="ORF">Mal33_13760</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019829">
        <property type="term" value="F:ATPase-coupled cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.620.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
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    </evidence>
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        <source>
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        <source>
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        <source>
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        </source>
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            <dbReference type="EMBL" id="QDV55405.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="815" mass="85617" checksum="671286FCF02EBA57" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
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                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
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                <person name="Op den Camp H."/>
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                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
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                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
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                <person name="Jogler C."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQT3</accession>
    <name>A0A518IQT3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">4,4'-diaponeurosporenoate glycosyltransferase</fullName>
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        </submittedName>
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        <name evidence="3" type="primary">crtQ</name>
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        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
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                <person name="Jetten M.S.M."/>
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                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
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    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
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            <end position="193"/>
        </location>
    </feature>
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        </location>
    </feature>
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        </location>
    </feature>
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        <location>
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        </location>
    </feature>
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        <location>
            <begin position="43"/>
            <end position="147"/>
        </location>
    </feature>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="QDV55456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="378" mass="41438" checksum="926925B2DE2B5A6E" modified="2019-10-16" version="1">MIAIALASLCLLLTGIPSAMIAWNLCCFRRLPTQVDDRPTPVSVLVPARDEAAGIAATLERLLASEGVDLEVVVLDDDSQDATTAIVAGIAEKDSRLRIAPGDELPRDWNGKQFACWQLSKLARHNRLLFLDADVHVEPDTIARLSHCMDRRAGQPQPLALLSGFPHQETVGWIETAIVPLMHFVLLGFLPIWRMQRVTDPAYAAGCGQIFMTDRHAYELAGGHAAIARSRHDGIKLPRVYRQAELMTDVIDGTDLASVRMYRSGAEVFDGVIKNADEALARPALIVPVTLFCLAPLAAMVAMIGFAIAGAWIASAIAAFAFCIATLSRVASVRRFRQPLASAWLHPFALVLFAGLQWIALWRHSRGRRVAWRGRIES</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IR10</accession>
    <name>A0A518IR10_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Type IV pilin biogenesis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Mal33_15020</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GSP F family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.81.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003004">
        <property type="entry name" value="GspF/PilC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018076">
        <property type="entry name" value="T2SS_GspF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042094">
        <property type="entry name" value="T2SS_GspF_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30012">
        <property type="entry name" value="PTHR30012"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00482">
        <property type="entry name" value="T2SSF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="159"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="213"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="360"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="domain" description="T2SSF" evidence="8">
        <location>
            <begin position="60"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="T2SSF" evidence="8">
        <location>
            <begin position="257"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV55525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="387" mass="43112" checksum="613479853630F302" modified="2019-10-16" version="1">MKFPLNQQNFPTAYRFGSALVRGMRTTGRLQITSNFPGQRWRLSSRIANEPLAAKQRSLLRVLAIAHSQGLSTPEWIANLADEHHGRYRRRLLRLAGRLQAGSSLVEALEQTPDALSDEMVLAIRFGQQSGTLAATFDQLLTAPVDDGLQASPTARYGMFYLVGMMLLYLLVLSFLALRIFPTLMQIAEEFEYHPPAAMRSLRAVGRFLEGSFFLWVLVGFAGLRLVTSGLMQRFYRRVWASRLLRPVVRLRSAELLRLLSPAVAAGRPLGGALSTLARHHYDRNVRAKLLFARNEVEQGSDPWSSLSAAGLLQRDESEALAGSTSNGTRAWLMHRLADRHQRQFGRRVGLLMSLLQPAIVLAMAAIVAWIGFAFFGFLSGIILILA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IR31</accession>
    <name>A0A518IR31_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Bifunctional NMN adenylyltransferase/Nudix hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_15340</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the Nudix hydrolase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020476">
        <property type="entry name" value="Nudix_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00502">
        <property type="entry name" value="NUDIXFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="3">
        <location>
            <begin position="39"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV55557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="175" mass="19321" checksum="3F2DD4A03506605D" modified="2019-10-16" version="1">MNLPIPQTFHFCPRCGAAATAIGKDPFQCSACQYTYHFGPTVAVGGIVTDAQGRVLLLRRARDPGKGKWGLPGGFVDSGETGEMALIREIQEEVRLNVESFQYLTSYTNSYEYRGLIIPVVDLFYTCQIVDLAALEAEPSEVQSTSFCDLGPEHLENMAFESNRLALQTFLESRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IR45</accession>
    <name>A0A518IR45_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">3 beta-hydroxysteroid dehydrogenase/Delta 5--&gt;4-isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_15270</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003854">
        <property type="term" value="F:3-beta-hydroxy-delta5-steroid dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006694">
        <property type="term" value="P:steroid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002225">
        <property type="entry name" value="3Beta_OHSteriod_DH/Estase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01073">
        <property type="entry name" value="3Beta_HSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3Beta_HSD" evidence="1">
        <location>
            <begin position="4"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="330" mass="36313" checksum="479087AC779F9F63" modified="2019-10-16" version="1">MRVLVTGCGGFLGAEIVRQLLARGDDVVGLGRRDYPQLAEAGMQQVRGDVRNQTAVLRATEDVDAVIHTAAIAGVWGSYQHYFETNTLGTRHVIDACHQREIRSLVFCSSPSVTFGGDDQTGVDESEPYPDDYLCHYPRTKAAAEQEVLAANQPGRLLTCALRPHLIWAPDDPHLFPRLIQRARAGRLVRVGSGENLIDTIHVRNAAHAHLLALDRISSGETEAAGRAYFLSQGEPVGCWAWLSEILTAAGVEVPTRSISYRTAYKIGHGLELIYAATRRTSEPPMTRFVAAQLAKDHYFDITAARRLLGYEPIISTAEGLAELKSQWRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRK7</accession>
    <name>A0A518IRK7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF1080 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_16620</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010496">
        <property type="entry name" value="3-keto-disaccharide_hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06439">
        <property type="entry name" value="DUF1080"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021849759" description="DUF1080 domain-containing protein" evidence="1">
        <location>
            <begin position="32"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1080" evidence="2">
        <location>
            <begin position="98"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="236" mass="26240" checksum="A70C3046F66AACA3" modified="2019-10-16" version="1" precursor="true">MRYSPLRSVASLPRLALFACIFSLSAALAVADESANGGWIDLKLQRDTVWEPCNFGGDGEVEFSENQAVLEMGDPLTGIRLVKEFPKDGYEIQFEASRLEGFDFFVGLTFPVAESHCSLILGGWSGAVIGLSNINGADASNNPTTREGDFDNNRWYRVRVRVAADRITAWVDDKQWVDQPRQGVEFGIRGEMDPSTPLGIATYQCKVAYRKIQYRRLNSGEVKPSHKPQPTESKSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IS18</accession>
    <name>A0A518IS18_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">2-deoxystreptamine glucosyltransferase</fullName>
            <ecNumber evidence="1">2.4.1.284</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">kanF</name>
        <name evidence="1" type="ORF">Mal33_18530</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.4.1.284" evidence="1"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102318">
        <property type="term" value="F:2-deoxystreptamine glucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="404" mass="45340" checksum="00F954A67946270D" modified="2019-10-16" version="1">MNTELQSHPKPTRCDAPVVDARVVLLTHYIPIYQLPIYQELSRQIRDFHVLLSTDVEPNRHFQPRWEGLDVTLQKTLTLQRRWRHSAGFDDTLYVHVPYDTGRQLRRLQPDIVLSLELGFRSLASSLHRILHRRSKLILCTYMSQHTEQGRGMMRAAARRWLIGRADAITYNGPSCFDVLSDLGADPKRLFHFPYAANPDSIYTGPLQPSGSPSVTRMLYIGQMTQRKGVEAMVEQVVRYAQQHADQEFQLTMVGEGPLREPLSAVATPANLGIEFTGNLPSEQLPTLMPAHDLLIFPTLADEWGLVVNEALHSGLPVIGSRLAQASTTLLQDDRNGWLYDPRDDSGLADCLDRWLACDVADRASMAGACRDSVRDRTPAFAASGLIDACQFVLGHSTNDRCDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IS44</accession>
    <name>A0A518IS44_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_18700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002220">
        <property type="entry name" value="DapA-like"/>
    </dbReference>
    <dbReference type="SMART" id="SM01130">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="319" mass="35261" checksum="814763B8979BB81F" modified="2019-10-16" version="1">MDPTTLLRPRRKITGISAILLPLLENNEVDWDAFRQHVLRTADAGLTPAVNMDTGYVNLIDEATRLQVLDVTRETLGSGPFVAGAFVGDTPGSTLALDAYKSRIDEITACGATPVIFQSYGLTDQRDAEIVSSYEQIGKTCDQFIGFELGQCFLPFGKIYSTDVYRQLMLLPQCIGAKHSSLSRAAEWERLALRDQLRPEFKVFTGNDLAIDMVMYGSDYLLGLSTFAPDLFARRDAYWAAGDPAFYELNDALQYLGFLTFRQPVPGYKHSAAMFLHLRGWIATNKTYPGSPQRPDSDLPILEDVARLLGISLAKGGNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IT13</accession>
    <name>A0A518IT13_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_22000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022230545" evidence="1">
        <location>
            <begin position="29"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="431" mass="47579" checksum="6E70C4753B0DF2C2" modified="2019-10-16" version="1" precursor="true">MPTTSKTTSLQIAIFCLALALPTAMLSAQPTGFNYDEAKVPAYTLPDPLVMADGTPVTSADQWPKRREEIMQLFLEEVYGKAPGKPEGLHFKVVEQSDDAVNGKATRKQVRVFFDVDETVAMDILIYLPKKSVEANKPVPTFLTLNFFGNHSISDDPAILLSESWMRSSKEKGVVKNRATEASRGASANRWPVEMIIDRGYGLATIYYGDIDPDFDDGFKNGVHALYDPPAKDGWGSLATWAWGLSRAMDYFETDGEIDAKRVAVFGHSRLGKTSLWAGASDPRFSITISNDSGCGGAALSRRAFGETVARINKSFPHWFCDNYLKYSDNEGACPVDQHQLVALIAPRSVYIASAEDDTWADPRGEFLSAVHAAPVYRLLGTDGIGGATEMPPVNKPIMHTLGYHIRTGKHDVTDFDWNAYMDFADRRWGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITD1</accession>
    <name>A0A518ITD1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_23120</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="113" mass="12116" checksum="64ADDC569458B3C5" modified="2019-10-16" version="1">MLRVVLLSAFVIAGFGIVGCGGDPEPTATEPQAPGQMAKSDDQKMEYLIEMLHRKNSEKKNAQAARELGRMGAFAKDAIPELQKAVQQTSDDKVRTDAQAAIKEIETAAATAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITE2</accession>
    <name>A0A518ITE2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidase M16 inactive domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_23250</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="SSF63411"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M16" evidence="1">
        <location>
            <begin position="6"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M16_C" evidence="2">
        <location>
            <begin position="148"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="390" mass="43196" checksum="41E323F39CB89BB9" modified="2019-10-16" version="1">MPWLRSAAFAFMLPAGCRYEPHDRLGLAGFVNEMIQRGAGNYSSRDLVAVQDNLGLDRSSSISTAHGSFGGSMPAESLPEALTLYADIVRHPHLPGDQIEDARLMCLQELAAAEDDLPQTLMNRLKQMHFGDVLGRTSLGDEAGLMAIDAADLRRFYQQHYQPRGAMLSVAGNFDWDVVRDHVEKLFADWQPHDPAPDQPIVGRAGYEHIEHPSQQTHLGIAFPAVRYGDPEYYPMRAAVGVLSDGMSSRLFTRVREERGLCYTISAGCHSTREGGGVFCYAGTTAERAQETLDVTLQELQGIADGIEEGELERLKVRIQSSLIMEQESSASRASAIVSDWYLLGRVQSRDELQKKIDALTTADLVDYWKRNPPKDLRIVTVGPEPLKVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITE7</accession>
    <name>A0A518ITE7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_23430</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="332" mass="35830" checksum="3E18C1A8F10D365C" modified="2019-10-16" version="1">MSWFQQLTGIDESTPQQVRAQLSVDDEELVCPDGTRIACGCLETPTLAELRARAAATDSPRGRLSLREIVADVRRLHADSGNANALFQVASQFNLLEMASPSVTPERGVGIYEHDHTQGPACAVACGAGTIYRNYFAAVGDRVGQSRDHQIDCSADLGRLLGNREDQLWRMQNGYLFPTDPGLRQISRTLESAAADELDSYRDTLRIGLQWNTAVTLAGSSHRVSQAYCSALPVAYGSQPAAEWTAFAKLVLEAAYEATLAAAVVNLAETGSNKLYLTLLGGGVFGNRNEWIIAAIERAVASYRETPLDVAIVSYGASHPPVADLIQQFSTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITH6</accession>
    <name>A0A518ITH6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_23720</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="86" mass="8988" checksum="5E85D0ADA550B399" modified="2019-10-16" version="1">MQTRVDAVNQPKRIPMRPLLTLTTAILIPSTLFAHPGHGSVASETAPALHYLTSGAHIGWAAVVAIAAVAAIAVVRSRRADARRAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITH9</accession>
    <name>A0A518ITH9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_23840</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="62" mass="6796" checksum="1EC7DE0F6E8C415F" modified="2019-10-16" version="1">MKTSKAETRLIDTPAGAFAALISARRSGDRMLERDMILTLRQRFGVEVTFGTTDQPEVPANG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITL6</accession>
    <name>A0A518ITL6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_24210</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="95" mass="10299" checksum="CBF7567D2E9F216C" modified="2019-10-16" version="1">MHFVSPRIGIVQDGFGAVLFVAGESHPTQIANRDRCHHPILIDANKLPQLIARFDLGTDVDGPVENLGVEGSQDFGSIQIEDSAFDSRFGGVQPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITQ4</accession>
    <name>A0A518ITQ4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_24590</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="70"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="167" mass="18028" checksum="7D986B4003E63C9E" modified="2019-10-16" version="1">MPPPKSDALQGLARSRQTDAGVSVRGRRAGAPCGCLPFASSTAITFSLPPRSFSCFRCRPRQQVAMLRPAIFASALLLTVCATATALLSYVADVSKLQIQCRSNRLGNTARQTSCRSPNDRDVTPRESQVEKGGAIQAANVFRPSSRWIQGTLAILANARCCFWAVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITR1</accession>
    <name>A0A518ITR1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_24660</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="434"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="435"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="463" mass="51017" checksum="62D2AAE3AE021274" modified="2019-10-16" version="1">MNSIMLEQPSIDCLVREMRDDGCDAVLNCFGDLEFSGSDHEDWQLKLQDRTPELMAYLGSVRPDDQPPVGDSLMRGMMRQHGIGAPWSSKELDDAKIDTQFLVNEVLVSGQPCVIAGASKSMKTSTAIDLAISLASGSPFLGRFLIPAAKRVLLLSAESGEGTIQETSRRVAKSKGLRLPACDSVQWGFWVPRAKDAEHLAILDYQLKESGAEVVVIDPLYQCLAGEDMSNLSMNGRQLQAIVGVCKQRNVTPVLVDHVKRSSTNASYHKPLELSDISGAGKAEFFRQWILLGRRQRFNPEHPFHRLWMTLGGSAGHCNMYALDIDESREATTKGRAWKVCVRSKAIAEAEDAKQRDASGIAKREMAANATLEENMQRVRDVFKPESNDKGWSKRQIRDALTPSLSGDTVNKVLERLVELGEVAVIPAGTVRNSHPRYRRTQPVGQAMNPTSGGTAGTKRDDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITT9</accession>
    <name>A0A518ITT9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_24960</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="42" mass="4989" checksum="445D600B928D7D0F" modified="2019-10-16" version="1">MIETMGDIALLVLCLIYVLTPREPQLAWRRNLNRKHPSEKRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IU61</accession>
    <name>A0A518IU61_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Prenyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_26190</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016765">
        <property type="term" value="F:transferase activity, transferring alkyl or aryl (other than methyl) groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000537">
        <property type="entry name" value="UbiA_prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044878">
        <property type="entry name" value="UbiA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01040">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="46"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="94"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="120"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="149"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="179"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="210"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="249"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="290"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV56627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="324" mass="34056" checksum="44EC718A6C9F3BEE" modified="2019-10-16" version="1">MSSPAPSPTLRDWCQLVRLPNVFTVIADTTAAFLLVAHQLVPLPRYGIVLAAVVCIYWAGMILNDVWDIEIDRQERSKRPLPAGKISLPAARRAGWGLLIAGVALSFAVGFVPHGDAPPSLVPGGIAVLLAAMVVLYDGPVKRTPLAPMAMGLCRFFSFLLGASAAVTSVSEFPFVPPHVLGIAAGLGVYIVGVTCMARGEAVGGDKQKVPLIFGLVITIVGMAMIAGGPQFAPADAIAKFQIDPQRQFSLLIGLLAFTIIHRAFRAILNPEPYAIQMNIKHAILTIIPLAAAVALLSAGVLAGLMVFALAVPAMTLGAFLRVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUI4</accession>
    <name>A0A518IUI4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">GBBH-like_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_27550</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2020.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010376">
        <property type="entry name" value="GBBH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038492">
        <property type="entry name" value="GBBH-like_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06155">
        <property type="entry name" value="GBBH-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GBBH-like_N" evidence="4">
        <location>
            <begin position="14"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="42"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="42"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV56756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="123" mass="13566" checksum="3BC259CC632FB6B3" modified="2019-10-16" version="1">MSALPNEIARIADGLRITWSDELVTQYSARQLRDACPCATCREKRRDAEPADDEIDDAAEASPKPKPKPMTLPVLSPQETRPIAVLGMRPVGNYAYNIAFSDGHDSGLFTFDFLRKLKSSAQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUL8</accession>
    <name>A0A518IUL8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Death domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_27820</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000488">
        <property type="entry name" value="Death_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025427">
        <property type="entry name" value="DUF4160"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13711">
        <property type="entry name" value="DUF4160"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50017">
        <property type="entry name" value="DEATH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Death" evidence="1">
        <location>
            <begin position="43"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="78" mass="9275" checksum="75A06920DBFCC34F" modified="2019-10-16" version="1">MPTVLRSGPYRFYFYSHEPNEPSHVHVDRDEDSAKYWLQPMSLARNLGFRGHELREIERIIGDNQQELLEAWNGRFGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUY4</accession>
    <name>A0A518IUY4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Addiction module component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_28930</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013406">
        <property type="entry name" value="CHP02574_addiction_mod"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09720">
        <property type="entry name" value="Unstab_antitox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02574">
        <property type="entry name" value="stabl_TIGR02574"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="80" mass="8929" checksum="D8EB74E09DA48A0F" modified="2019-10-16" version="1">MSQYQDILANATQLPINDRLRLIDDLASSIPDDHPPRLSPEWLAEIDRRSNEIDAGTAETENWSTIRARLFGKHGVGDSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUY7</accession>
    <name>A0A518IUY7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_29050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022227">
        <property type="entry name" value="DUF3754"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12576">
        <property type="entry name" value="DUF3754"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="270"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="433" mass="48784" checksum="7890FC7C27D868F1" modified="2019-10-16" version="1">MSLGSRKGVRLAQESLSGEYIAEDAPHWKAEPFIPITAAELKSVLLAHPRAAAQADHLHRVFESLTSILNHDYRNLHQQLETHYSVLDPDRDLKLLTEPTDAQCDASLRHMRGYLHDLLRAANFTQLDQQQIRGAIQTSSDWGVRLQINFDIFESIDVYARGDIVGMRTRRLWKSYWKMSEMEVPIYQRLVAVFKLKPDAKLVGAHAGGQYHRDRLHLSMFKNIPQADVDMLLPGSSIRFSWLDRTKIFAPTLGGIGVTVFKILRGAVVIAATGLAAVMGVAVLAIGIIGYAVRSIVSYFHTKDKYLLNMTRSLYYQKLDSNAGVIYRLLQEARQQDLLESIVVYFILATSDEPMSEAAMCKRVELLLKDLLAIEIRFDPYSAMKRLHRLGIVLDGGGDTVSVLSPETSVRQLDHYWDNLMSIDRATSSESGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IV41</accession>
    <name>A0A518IV41_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Trk system potassium uptake protein TrkA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">trkA</name>
        <name evidence="7" type="ORF">Mal33_29630</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015079">
        <property type="term" value="F:potassium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1450">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006036">
        <property type="entry name" value="K_uptake_TrkA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006037">
        <property type="entry name" value="RCK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036721">
        <property type="entry name" value="RCK_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003148">
        <property type="entry name" value="RCK_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02080">
        <property type="entry name" value="TrkA_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02254">
        <property type="entry name" value="TrkA_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00335">
        <property type="entry name" value="KUPTAKETRKA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116726">
        <property type="entry name" value="SSF116726"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51202">
        <property type="entry name" value="RCK_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51201">
        <property type="entry name" value="RCK_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0406">Ion transport</keyword>
    <keyword evidence="4" id="KW-0520">NAD</keyword>
    <keyword evidence="3" id="KW-0630">Potassium</keyword>
    <keyword evidence="2" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="RCK N-terminal" evidence="5">
        <location>
            <begin position="2"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="RCK C-terminal" evidence="6">
        <location>
            <begin position="141"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="domain" description="RCK N-terminal" evidence="5">
        <location>
            <begin position="231"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="domain" description="RCK C-terminal" evidence="6">
        <location>
            <begin position="366"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00017378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV56962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="448" mass="48319" checksum="836219AD94B43788" modified="2019-10-16" version="1">MQAIILGAGTVGTWIADLLCRARHSVTVIDTNPEEVRRINAELDVRAIHGSGSQSTVLFQADICGADICLAVTGDDEVNIVAASMAKALGARRAIARVYAPAFRDMSTFDYQQHFNIDRLLSLEQLSATELARSIRNPGSIPLEHFARGQLEVYELTVAIKAPAVGKPLRELKLSHGVRIGSISRQGRRWIAGGEDEIHAGDSISLIGFPKDVAEARAQFAPESTRVPRRNVIIAGGGETGYHLAQSLNKSEYRILILDEDPQRCEHLATLLPSATVVTANANRRSVLEDEGVGKADYFVACTGNDENNIMAGVEARELGAHKVMAVVGRPDYANVVAKLGIDVAVSERDAVARQVMGFMNDGPIISQSQLPEGSIGVYEIEIDEDVPVTKAPLMQLPLSGRCLIAAIMRDGFVRVPTAKDQLRLGDVIVALIDQNTLDSTISLFKVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVC6</accession>
    <name>A0A518IVC6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_30370</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="76" mass="8410" checksum="AA96E5C806CCBB18" modified="2019-10-16" version="1">MGTRLNEIPNAPPRSFNRVGNAPRVQALDQPKTRGPMGTRLNEIPNAPPLSFNRVGNAPRVQTPDRPKRATQWARG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVE5</accession>
    <name>A0A518IVE5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Hemin transport system permease protein HmuU</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">hmuU</name>
        <name evidence="8" type="ORF">Mal33_30570</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037294">
        <property type="entry name" value="ABC_BtuC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000522">
        <property type="entry name" value="ABC_transptr_permease_BtuC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30472">
        <property type="entry name" value="PTHR30472"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01032">
        <property type="entry name" value="FecCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81345">
        <property type="entry name" value="SSF81345"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="60"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="88"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="112"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="149"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="191"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="237"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="276"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="307"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV57056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="334" mass="33653" checksum="007DE9B36D53399C" modified="2019-10-16" version="1">MSARWNILFASMVMLVVAVCVCLVGATSISPSELFAAATGGASLSESDRAILFQLRLPRIVAAAFVGGSLAAAGVGFQGLFRNPLAEPYVIGASSGAGLGVAIVVICGLRASIWSIGAVASLAMLGSVGVVMLVLIVGSLARTTSTTSLLLAGVVISSMVNAIVSALMFLFDQKAVVILSWLMGSLASSHWGTAILAATLGGAGMIGIGLLSRPLDAFALGDTASQSLGLDLSRFRWLIIGAASLATAGAVAASGVIGFVGLIAPHMARLFVGPRHAVLIPMSVCIGATLMLLADAVARTVIAPAELPVGIVTALLGCPVFLWLLLSRRTGASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IW05</accession>
    <name>A0A518IW05_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD dependent epimerase/dehydratase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_32700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="1">
        <location>
            <begin position="14"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="290" mass="31787" checksum="71C9A28C37B6E45F" modified="2019-10-16" version="1">MENSKKTALIFGCGYLGKRVAQRLLDRDWHVSAVTRRRETATELSAAGIAPIVADWTRPSMLRDLPQTDRILIAVGWDRQGGQSQYDVYVGGLRNALQATSPQANLVYVSSTGVYHQSGGLWVDEASPCCPAIGSGGWAHLQAEALLRQNRPGSPSTILRMAGLYGPGRVPRGRDILSGQPLAAPTEGYLNLIHIEDAATAVMAAWETKSDGAKTYVVADGTPVIRRTYYEEIARVLGRPLPTFVSPDPAAMVSRRATTSKRIWTARFRRNLCPRLAFPDYRAGLRDVLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWD4</accession>
    <name>A0A518IWD4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Xylose isomerase-like TIM barrel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_34100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013022">
        <property type="entry name" value="Xyl_isomerase-like_TIM-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01261">
        <property type="entry name" value="AP_endonuc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="SSF51658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022083547" evidence="1">
        <location>
            <begin position="38"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="domain" description="AP_endonuc_2" evidence="2">
        <location>
            <begin position="78"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="313" mass="34611" checksum="9DE6D2807CF557DD" modified="2019-10-16" version="1" precursor="true">MQDSHFTAQSPLSRRQLLTSSIAAASLAAMSPQLAGAAEMIPGRHAPKFKFSLAAYSYRSLLQGKGDAAPKMDLLGFIDECARMQLDGVELTSYYMPEEPTEAYLIGLRSHCFRQGLAVSGTAIRNDFGHSETATRNRELEHVRRWIDHAATLHAPMIRIFAGHGQKGNSPEQTHELMVEGIQKSCEYAGKHGIYLALENHGGVTASADGLLKLVRDVDSPWLGVNLDTGNFRFGGEPYEQMEAVAKYAVNVQVKVVVKDADGKPQPMDFPRLKKILTDANYRGFVVLEYEEPGDVPAECRRYVQQMRTDLAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWG9</accession>
    <name>A0A518IWG9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative peroxiredoxin</fullName>
            <ecNumber evidence="6">1.11.1.15</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">tsaA</name>
        <name evidence="6" type="ORF">Mal33_34500</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.15" evidence="6"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051920">
        <property type="term" value="F:peroxiredoxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024706">
        <property type="entry name" value="Peroxiredoxin_AhpC-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019479">
        <property type="entry name" value="Peroxiredoxin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10417">
        <property type="entry name" value="1-cysPrx_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000239">
        <property type="entry name" value="AHPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 6" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="5">
        <location>
            <begin position="3"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine sulfenic acid (-SOH) intermediate" evidence="4">
        <location>
            <position position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000239-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV57440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="197" mass="21786" checksum="AE204E96AA9845DA" modified="2019-10-16" version="1">MTQLVTHEAPNFTAQAVMADGSFKSISLTDYRGKYVVLFFYPLDFTFVCPTEIIAMSEAAKEFEALNVQLLGVSVDSHFSHLAWRNTPRAQGGLGDIQYPLVADLNKQIARDYDVLLDGGIALRGLFLIDKDGVVRHQVVNDLPLGRSVDEALRMCKALQYFEANGEVCPANWTEGARTIKPDVDASKEFFGAEYSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWI4</accession>
    <name>A0A518IWI4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative lipoprotein YiaD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">yiaD</name>
        <name evidence="4" type="ORF">Mal33_34460</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07185">
        <property type="entry name" value="OmpA_C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006665">
        <property type="entry name" value="OmpA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036737">
        <property type="entry name" value="OmpA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00691">
        <property type="entry name" value="OmpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103088">
        <property type="entry name" value="SSF103088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51123">
        <property type="entry name" value="OMPA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OmpA-like" evidence="3">
        <location>
            <begin position="117"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="8"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV57436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="241" mass="26453" checksum="7F9FD1C87D1B2D3E" modified="2019-10-16" version="1">MAADPNSLQAAQAQLADLERRVRHLDDNNRQLHTQLAQAEQQSQVYKDEVNLMRTQLAEVTGRMQEAHLAAADAQQQFQGLQASSRFRGGATITPNTNLRQAASQLSLGGLPVSFENEAIRIRIPSDQLFQRNSAQIAGGAAAMLDPIAAAIQQNFPRQKIGIEGYTDDQQLYGGMYGSNHQLSAAQASAVFEHLTRRNNLPPQQLFTLAQGSNYPRGDNTTAVGRAANRRVEIVIYPETF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IX18</accession>
    <name>A0A518IX18_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Calcineurin-like phosphoesterase superfamily domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_36410</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos" evidence="1">
        <location>
            <begin position="56"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="330" mass="36686" checksum="4778783C678F98D5" modified="2019-10-16" version="1">MKRRTFFGLGTAAAGLPLINAGESRAAQPEGKSTRGSFSVDGNLVRFYSADIRKPLRVLVAADTHLFLDDERGKPFHEFSGRMAGAYNTTRHFKTGEATNPQNSFTQIIERAQERNVDLLALVGDIFSFPSEAAIEWVADQLAASKLRYCYVAGNHDWHYEGMPGSIDELRATWIEKRLKPLYQGNNPLMSAYDIGDVRFLAIDNSTYEILPEQLDFFRAQAETGKPLVLTVHIPMFAPGRPVGFGCGHPEWGAQTDRNHKIERRPPWPTTGHTQATLDFHRDVFTTPNLLGIFAGHTHRSSVDVINGIPQFVTDDNASGAFMDVELLPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IX25</accession>
    <name>A0A518IX25_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">Acylphosphatase</fullName>
            <ecNumber evidence="3 4">3.6.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">acyP</name>
        <name evidence="7" type="ORF">Mal33_36530</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>an acyl phosphate + H2O = a carboxylate + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14965"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29067"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:59918"/>
            <dbReference type="EC" id="3.6.1.7"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the acylphosphatase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.7" evidence="3 4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003998">
        <property type="term" value="F:acylphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020456">
        <property type="entry name" value="Acylphosphatase"/>
    </dbReference>
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        <property type="entry name" value="Acylphosphatase-like_dom"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="3"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="18"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV57640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="89" mass="10015" checksum="926E98006FB6ADCB" modified="2019-10-16" version="1">MERIEVFYRGHVQGVGFRYNACEQADGLAVTGWVQNLPDRRVQMVAEGSIGDLKKLLRRIDQSMSGNIRDKSVAWQAATGQLAPFQIKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IX53</accession>
    <name>A0A518IX53_9BACT</name>
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        <submittedName>
            <fullName evidence="5">Zinc dependent phospholipase C</fullName>
        </submittedName>
    </protein>
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
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                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
    <dbReference type="Pfam" id="PF14229">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF48537"/>
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    </dbReference>
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    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4332" evidence="4">
        <location>
            <begin position="429"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="302"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="316"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF14229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV57661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="559" mass="61078" checksum="086833F75688E815" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name type="scientific">Rosistilla oblonga</name>
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        <lineage>
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    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="74" mass="8210" checksum="EE477F8BC923A8E3" modified="2019-10-16" version="1">MCAGRRGVDHSCVATMASRQFTCTPEGNLCRLLHWRPESDRAWLAREQSPPEGGLYLSLAASSDSQTLLRISFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXF4</accession>
    <name>A0A518IXF4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_37800</name>
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    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
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                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="113" mass="12798" checksum="14E5692D4BA61358" modified="2019-10-16" version="1">MEPKNIPSPQLRLRDIPADQAEMVVIEEFALTFDGYAFWDEQGESCSDEAKSDCQCLDHLRTRLFFAQRAGRHSAGLERERAVPILRALRTELSAPTATICRHEAKPPHPLPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXL8</accession>
    <name>A0A518IXL8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_38310</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Planctomycetia</taxon>
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            <taxon>Rosistilla</taxon>
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    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
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                <person name="Bruemmer F."/>
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                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="125"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="147" mass="17252" checksum="F4AB777D0A0C6B6C" modified="2019-10-16" version="1">MPSHASKQHYSEQTLRQVAADCRRSLQRGQFDVEQSRVERLRCVDDQLETEEQFGRQLWYFEGRAFSSDDRRVRVYGVIEYSLQYGLQELVEDGVFDAPDQRDRFREIYHHTPSRFSWRHPSIRMLIAGTFGVGAAYLAYVASRLIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXW1</accession>
    <name>A0A518IXW1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">GHMP_kinases_C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_39410</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.890">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013750">
        <property type="entry name" value="GHMP_kinase_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036554">
        <property type="entry name" value="GHMP_kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004422">
        <property type="entry name" value="RFAP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20861:SF6">
        <property type="entry name" value="PTHR20861:SF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08544">
        <property type="entry name" value="GHMP_kinases_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004884">
        <property type="entry name" value="Sugar_kin_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GHMP_kinases_C" evidence="2">
        <location>
            <begin position="237"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="352" mass="37782" checksum="FE9DBB725F3C29D3" modified="2019-10-16" version="1">MGMSANDPSSEATCASHLPTHPVACQRVDVVTGSRLHFGLLSTQPVDRVCYGGCGLMIRRPSVHVRAVRSDRFRFAGEFESRCREVAQRFVDHFGLPSLPPCDLQLLQSSDAHAGLGSGTQINLAVATALTTLFQMPISLEQLAAEIAARGRRSAIGVHGFAHGGLVVESGIPEGQTLGRLSATQPFPSHWRILLVRPRQFKAHVHGGVEQAHFAQLAAAAPAERDALLAIMNDEILPAIIAHDFDAFCESVSRYNHTSGMLFAPVQGGAYNGPQLEALVATLRDAGCQGIGQSSWGPTIFAFCPDQDSAEAMRQRLLSAGDGNRLKIEITQARNKPASVCAKRQSSECEIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXY1</accession>
    <name>A0A518IXY1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="11 12">ATP synthase subunit a</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">ATP synthase F0 sector subunit a</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">F-ATPase subunit 6</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11 14" type="primary">atpB</name>
        <name evidence="14" type="ORF">Mal33_39520</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11 12">Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11 12">Cell membrane</location>
            <topology evidence="11 12">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11 12">Belongs to the ATPase A chain family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045263">
        <property type="term" value="C:proton-transporting ATP synthase complex, coupling factor F(o)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01393">
        <property type="entry name" value="ATP_synth_a_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000568">
        <property type="entry name" value="ATP_synth_F0_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045083">
        <property type="entry name" value="ATP_synth_F0_asu_bact/mt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035908">
        <property type="entry name" value="F0_ATP_A_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11410">
        <property type="entry name" value="PTHR11410"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00119">
        <property type="entry name" value="ATP-synt_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00123">
        <property type="entry name" value="ATPASEA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81336">
        <property type="entry name" value="SSF81336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01131">
        <property type="entry name" value="ATP_synt_6_or_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="11" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 11 12" id="KW-0138">CF(0)</keyword>
    <keyword evidence="6 11 12" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="8 11 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="51"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="121"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="167"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="207"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="232"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="261"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="287"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="311"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="QDV57936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="340" mass="37788" checksum="7BA5295FB541C01F" modified="2019-10-16" version="1">MLNISMLAAGHGPVDHVVPHTLHSEPLFTWQVGGPDYDNRWLNIQNGVYEFYITNHMVMTLVAAVLVILVFAWVSRRVRPVGPGLTKYQTRGRGAQLFELLCTFIRDEVARPNLKGLTDKYIYYVWTIFFFILFANILGLIPFGPILRLLTNDPGWEHWGGTATSNLGLNLVLAMASFIAIIVIGIREQGVVHFLAHFNPVGWDWKSPMIGMGLMMFVLEWMGLMIKCTVLAMRLFGTMMAGHLVIAAFIALIFDAAANGAVMGYGVGLAVLFGGVVLTLLELFICALQAFIFTFLTVLFISAGAVGEHDEEHEENPLSDESQMDVDKMIRPQDLRPVTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IY63</accession>
    <name>A0A518IY63_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_40410</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021849318" evidence="2">
        <location>
            <begin position="25"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="328" mass="37222" checksum="98BDD5E5F5C4CB11" modified="2019-10-16" version="1" precursor="true">MNVRIRLAHVMAFAGILVVTTATAQRPRPIVPGTGKLITAVGDDFEDPNWRYVPRNPKSTEDIDENQRGPTGKSVNGRWYEGIKRGHPDIVRRVPTPPGGLSGSGGSLLLKSMYTGVPGRGSSEPHNQDDFICNVQYRLNGRVQVESQPNVVTRVWLPKVKDWERRTGPHFGFRLALETTAVKESEGGFLMFKSKGPENEVYWPGMFVELKCKENTKQDYDYAYWRIRCDSRGRDFQGPAITTTGWWTLGMSCTTDGMVHYYISEGVDDLTQDDYVTSQFPYSYKTERLRSFFFNTMSRDDGRTWSTGVIVDDPMLYFANETRVASRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYR4</accession>
    <name>A0A518IYR4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator PleD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">pleD_4</name>
        <name evidence="3" type="ORF">Mal33_42500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd00060">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SSF49879"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="1">
        <location>
            <begin position="44"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="2">
        <location>
            <begin position="161"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="292" mass="32615" checksum="81481FECE5CCAA33" modified="2019-10-16" version="1">MSMLQEPTLLVDPATQDAVGSQRWLVQIHPLDLDRGPIEIMETIQIGRDSHCSLRLPDHSVSRRHAEIVKQGDHYTIRDLGSTNGVIINGQAVQSHELQTGDRIQLGSRIFRFLADHDLEAQYHETVYSMMTRDGLTGVFNKRYLLESLDREVARCRRYKRPIAVILLDIDHFKSINDTHGHLAGDEVLQQISSRLGDVLRSDEILARFGGEEFAIVIVESNRKNALDVAERCRKACAKEAFKTSAGLLEVTISLGVAAPAVDEIETRAALLDAADKYLYQAKHAGRNQVVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYS3</accession>
    <name>A0A518IYS3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DNA-directed RNA polymerase subunit alpha</fullName>
            <ecNumber evidence="3">2.7.7.6</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rpoA_2</name>
        <name evidence="3" type="ORF">Mal33_42460</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.7.6" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011773">
        <property type="entry name" value="DNA-dir_RpoA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011260">
        <property type="entry name" value="RNAP_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32108">
        <property type="entry name" value="PTHR32108"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03118">
        <property type="entry name" value="RNA_pol_A_CTD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="3" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="155"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_A_CTD" evidence="2">
        <location>
            <begin position="285"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_A_CTD" evidence="2">
        <location>
            <begin position="372"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="441" mass="48662" checksum="2CFF02598D8281E8" modified="2019-10-16" version="1">MAEAHMLDLKETLLSNASFGPQEIYVIRQAISDDFTHFTELKEGVGLLEQDTDRTPASQTRLGIGQFLLGRFQDAKQTLQSADGGALAQFYIGRCHFEHCDYAEAMASFEAAKTAGYNADECNLAIAAVHRYMGNAEQALATLDNMFGPVEQSAEYLYQRGATVAVLGGNLPEAVALYERAIQANPQHAGALFGLAVENDRHGNDDTALELYERASKAFPTGVGVLINLGLMSEDRNDFGKAQLCYKRILDCYPDHPQARLYMKDASASGNVLYDEETQRRNDRLAQVLNISVSNFELSVRSRNCLTKMGIDTLGDLTRTSEAELLASKNFGETSLYEIREILSSKGLTLGQFAHEKKTADPPVDTSHLSPAEQALLDRPISDLNLSVRARKCMVRLGLNTIGELLRKTADELLECKNFGVTSLVEIREKLEQHNLTLRGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYT3</accession>
    <name>A0A518IYT3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribonuclease PH</fullName>
            <shortName evidence="4">RNase PH</shortName>
            <ecNumber evidence="4">2.7.7.56</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">tRNA nucleotidyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4 7" type="primary">rph</name>
        <name evidence="7" type="ORF">Mal33_42620</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>phosphate + tRNA(n+1) = a ribonucleoside 5'-diphosphate + tRNA(n)</text>
            <dbReference type="Rhea" id="RHEA:10628"/>
            <dbReference type="Rhea" id="RHEA-COMP:17343"/>
            <dbReference type="Rhea" id="RHEA-COMP:17344"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57930"/>
            <dbReference type="ChEBI" id="CHEBI:173114"/>
            <dbReference type="EC" id="2.7.7.56"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homohexameric ring arranged as a trimer of dimers.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the RNase PH family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.56" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-exoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009022">
        <property type="term" value="F:tRNA nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016075">
        <property type="term" value="P:rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd11362">
        <property type="entry name" value="RNase_PH_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00564">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001247">
        <property type="entry name" value="ExoRNase_PH_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015847">
        <property type="entry name" value="ExoRNase_PH_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036345">
        <property type="entry name" value="ExoRNase_PH_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002381">
        <property type="entry name" value="RNase_PH_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018336">
        <property type="entry name" value="RNase_PH_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01138">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03725">
        <property type="entry name" value="RNase_PH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55666">
        <property type="entry name" value="SSF55666"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01966">
        <property type="entry name" value="RNasePH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01277">
        <property type="entry name" value="RIBONUCLEASE_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1 4" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="4 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 4" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="2 4" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="RNase_PH" evidence="5">
        <location>
            <begin position="7"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="RNase_PH_C" evidence="6">
        <location>
            <begin position="154"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphate (substrate) binding" evidence="4">
        <location>
            <begin position="120"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <note>substrate</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV58244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="234" mass="25185" checksum="07374D5678EB6C00" modified="2019-10-16" version="1">MDRPANQIREVSIERHYLKSSPGSVLYRCGETVVLCTASVSTSLPKWREGSGKGWVTAEYNMLPHSTSSRKQRDRGGKVDGRTTEIQRLIGRSLRAVVDLEALGELAVNIDCDVLQADGGTRTASITGGFIALVDAVESALPGSQIGDGPIRDYVAAISSGVIDNTVYLDLDYRLDSAADVDMNIVMTGAGRFVELQGTGEEATFDNDQLTQLLALGKQGIDQLIGLQKQALQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYU4</accession>
    <name>A0A518IYU4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="1" type="ORF">Mal33_42650</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="QDV58247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="66" mass="7101" checksum="D8EB12689C2D2028" modified="2019-10-16" version="1">MVEFDDPELEQLRTVADFAGLLAAKAAELSPAEALDVVLDKLAAHEADGGESISAESRLRELFRVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ29</accession>
    <name>A0A518IZ29_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ABC-2 family transporter protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_43600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="48"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="138"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="164"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="199"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="234"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="273"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="313"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="356"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="401"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="435"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="491"/>
            <end position="510"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="546" mass="60038" checksum="2F01CBD3A82E1872" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ83</accession>
    <name>A0A518IZ83_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Redox-sensing transcriptional repressor Rex</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6 8" type="primary">rex</name>
        <name evidence="8" type="ORF">Mal33_44110</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the transcriptional regulatory Rex family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051775">
        <property type="term" value="P:response to redox state"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01131">
        <property type="entry name" value="Rex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003781">
        <property type="entry name" value="CoA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009718">
        <property type="entry name" value="Rex_DNA-bd_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022876">
        <property type="entry name" value="Tscrpt_rep_Rex"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35786">
        <property type="entry name" value="PTHR35786"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02629">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06971">
        <property type="entry name" value="Put_DNA-bind_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00881">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0678">Repressor</keyword>
    <keyword evidence="5 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 6" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="CoA_binding" evidence="7">
        <location>
            <begin position="97"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="6">
        <location>
            <begin position="34"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="108"/>
            <end position="113"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV58393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="227" mass="23884" checksum="E76F8B12DDB7BDE4" modified="2019-10-16" version="1">MAAEPTQGDSSQELPSGIAINSSIPPATVARLILYARELSRLRREGESHVSSKLLGQLLSVSDAVVRRDVNHLGSMGQRGVGYEIGPLIGQIRQTMGTNLSWKVALIGAGSLGNALMRYRGFDEQGFQLVAAFDTDPAICSRNIGGIPVLPLEQLESTIVAEAVSLAILAVPVDAADAVAKRLAASGVVGILNFAPRTLPKFPGVCVVNVDLASELQQLTFAVVSQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZA7</accession>
    <name>A0A518IZA7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">dITP/XTP pyrophosphatase</fullName>
            <ecNumber evidence="6">3.6.1.66</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Non-canonical purine NTP pyrophosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Non-standard purine NTP pyrophosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Nucleoside-triphosphate diphosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Nucleoside-triphosphate pyrophosphatase</fullName>
            <shortName evidence="6">NTPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Mal33_44450</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>H2O + ITP = diphosphate + H(+) + IMP</text>
            <dbReference type="Rhea" id="RHEA:29399"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="ChEBI" id="CHEBI:61402"/>
            <dbReference type="EC" id="3.6.1.66"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>H2O + XTP = diphosphate + H(+) + XMP</text>
            <dbReference type="Rhea" id="RHEA:28610"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57464"/>
            <dbReference type="ChEBI" id="CHEBI:61314"/>
            <dbReference type="EC" id="3.6.1.66"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>dITP + H2O = dIMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:28342"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61194"/>
            <dbReference type="ChEBI" id="CHEBI:61382"/>
            <dbReference type="EC" id="3.6.1.66"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="6">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the HAM1 NTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.66" evidence="6"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035870">
        <property type="term" value="F:dITP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036220">
        <property type="term" value="F:ITP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017111">
        <property type="term" value="F:nucleoside-triphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036222">
        <property type="term" value="F:XTP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009117">
        <property type="term" value="P:nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009146">
        <property type="term" value="P:purine nucleoside triphosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00515">
        <property type="entry name" value="HAM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01405">
        <property type="entry name" value="Non_canon_purine_NTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020922">
        <property type="entry name" value="dITP/XTP_pyrophosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002637">
        <property type="entry name" value="Ham1p-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029001">
        <property type="entry name" value="ITPase-like_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11067">
        <property type="entry name" value="PTHR11067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01725">
        <property type="entry name" value="Ham1p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52972">
        <property type="entry name" value="SSF52972"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00042">
        <property type="entry name" value="TIGR00042"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="8"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="154"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="182"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="70"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV58424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="204" mass="22643" checksum="72C04C2B295CC7F0" modified="2019-10-16" version="1">MFELVLGTGNRKKAIEIQAVMPADRVRLTTLADWPTAIEVVEDGDSFAENARLKSTQQAKHLGQWVLGEDSGLSVDALDGAPGIYSARFSGDDATDEKNNDLLLERLEGVPLERRTAYYNCYLSLSDPDGNERLAANGKCCGRIIQQRHGTHGFGYDPMFEIPEYHLTFGQLGPSVKKALSHRARALRQFIPQLRRLLDQLAGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZB8</accession>
    <name>A0A518IZB8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">1,2-phenylacetyl-CoA epoxidase, subunit D</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">paaD</name>
        <name evidence="2" type="ORF">Mal33_44500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034904">
        <property type="entry name" value="FSCA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002744">
        <property type="entry name" value="MIP18-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01883">
        <property type="entry name" value="FeS_assembly_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117916">
        <property type="entry name" value="SSF117916"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FeS_assembly_P" evidence="1">
        <location>
            <begin position="5"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="105" mass="11738" checksum="D7ACC90F72218C18" modified="2019-10-16" version="1">MPLQEDTVRESLKKVIDPELFVNIVDLGLVYEVYITEKEDEKYDVKIDMTMTSPMCPAGPQLVAGAKAAIEECEGVEEAEVKVVMDPPWTPDCMTDDARDQLGIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZJ6</accession>
    <name>A0A518IZJ6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sodium-dependent dicarboxylate transporter SdcS</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">sdcS_2</name>
        <name evidence="8" type="ORF">Mal33_45450</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1450">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004680">
        <property type="entry name" value="Cit_transptr-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031312">
        <property type="entry name" value="Na/sul_symport_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006037">
        <property type="entry name" value="RCK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036721">
        <property type="entry name" value="RCK_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03600">
        <property type="entry name" value="CitMHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02080">
        <property type="entry name" value="TrkA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116726">
        <property type="entry name" value="SSF116726"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01271">
        <property type="entry name" value="NA_SULFATE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51202">
        <property type="entry name" value="RCK_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="5"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="28"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="96"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="136"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="175"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="419"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="442"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="467"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="505"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="550"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="592"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="domain" description="RCK C-terminal" evidence="7">
        <location>
            <begin position="221"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="domain" description="RCK C-terminal" evidence="7">
        <location>
            <begin position="317"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV58522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="614" mass="64651" checksum="6A2398C13052B4A7" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZL3</accession>
    <name>A0A518IZL3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ribosomal RNA large subunit methyltransferase H</fullName>
            <ecNumber evidence="1">2.1.1.177</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">23S rRNA (pseudouridine1915-N3)-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">23S rRNA m3Psi1915 methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">rRNA (pseudouridine-N3-)-methyltransferase RlmH</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1 2" type="primary">rlmH</name>
        <name evidence="2" type="ORF">Mal33_45610</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>pseudouridine(1915) in 23S rRNA + S-adenosyl-L-methionine = H(+) + N(3)-methylpseudouridine(1915) in 23S rRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42752"/>
            <dbReference type="Rhea" id="RHEA-COMP:10221"/>
            <dbReference type="Rhea" id="RHEA-COMP:10222"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:74486"/>
            <dbReference type="EC" id="2.1.1.177"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RNA methyltransferase RlmH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.177" evidence="1"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070038">
        <property type="term" value="F:rRNA (pseudouridine-N3-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd18081">
        <property type="entry name" value="RlmH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00658">
        <property type="entry name" value="23SrRNA_methyltr_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003742">
        <property type="entry name" value="RlmH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33603">
        <property type="entry name" value="PTHR33603"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02590">
        <property type="entry name" value="SPOUT_MTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004505">
        <property type="entry name" value="MT_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="1" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="1 2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="1">
        <location>
            <begin position="123"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="156" mass="18237" checksum="CC3E5D042C5DE043" modified="2019-10-16" version="1">MKIKLVWIGRSKDKNFADLIDQYRKRLSHYCSLEIAELKELKPGRLSAAELMKKEAELLLRQVADQDLMVLMDERGRQWTSMELSQWLQAKMNIATPRMTLVIGGAWGVDAKVTQRADRIWSLSKLTLTHDMARVFLIEQIYRGFTILRGEKYHNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZP9</accession>
    <name>A0A518IZP9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_45930</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011521">
        <property type="entry name" value="YTV"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07639">
        <property type="entry name" value="YTV"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021873556" evidence="1">
        <location>
            <begin position="24"/>
            <end position="491"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="491" mass="57302" checksum="93C51B9DB1A0EAE8" modified="2019-10-16" version="1" precursor="true">MRHFLMSGLFAAMIAVWCPMAFADCNDCGTSDSNASVAGSPSDVACGPQMVTKTIRVPQMVTETRVVNVAKTRQEQRTRTKTVYRNVQEQRSRTESYTVKVPQQRTRTESYTVKVPYTETQTYTVRVPQCSTKTVNYKVMVPECRTREESYTVMVPYTEQKTAKYMVKVPYTETKIVDYTVQVPYTETKVVDYTVQVPYTEQKTETYMVKVPYTETKTETYTVSVPYTETKIETYSVSVPYTETRTEEYTVSVPYTETETRVVTDACGCPQTICCQVQKTRCETRTRCINVCKTRCEERTREIKVCKTRCEERTREVKVCKTRCEERTRTYNVCKTRCETRQREVQVCKTRCETRQREVKVCKTRCEERTRCYTVKKCRPETRTRTVKYTVMVPECRTREVKVVNMVCETRERQVCKTRCETRQREVSYTVCVPECRTREVSYTVCKKVPEQVTETYTVCVPYCEQQTVEVQVCKNVCKEIQVPACNCCCN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZR1</accession>
    <name>A0A518IZR1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_46100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="202" mass="21992" checksum="06CA9AB3B6F37317" modified="2019-10-16" version="1">MYCSECGCEVNGKFCSNCGTRVQLGEVPEVFDWRQSYDFERITQSAEVNQRVTQAKAGAGRDTSSLLLDLIDAVASPMMGGISSLAIAKASQPLTAKLGFKTGKERREFVTLPPGEVLANLAVTLASIEHSITCVTFGDNHCHIRATLPPDLRAMEVRLSVNIDGAEQGMWITATAEAEGQWYDWGKCQSQLDRLFTGLRAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZT0</accession>
    <name>A0A518IZT0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_46230</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="142" mass="15534" checksum="32527AC70F2A7B5D" modified="2019-10-16" version="1">MHCLDYLAAAPNPPGAGSGSNSPRLPISMLGNQPIPNPRVQFGNAATQQFRVPTSMSIDKAWLVVNKAWLVARNQKGTGKFRRETKRGQASSGVHCLDHLMPVPKWHLPNHPHGARCLDRLSKRGQASSGVYCLDHLMPVPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZT5</accession>
    <name>A0A518IZT5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Outer membrane biogenesis protein BamB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_46210</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018391">
        <property type="entry name" value="PQQ_beta_propeller_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002372">
        <property type="entry name" value="PQQ_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13360">
        <property type="entry name" value="PQQ_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00564">
        <property type="entry name" value="PQQ"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021859726" evidence="1">
        <location>
            <begin position="28"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="422" mass="45632" checksum="2F85DC2369E43BD6" modified="2019-10-16" version="1" precursor="true">MIRSSSRLCLIVSSLVFAFWASSDSNAQDWTRFHGPNGSGYIADGKIPDSWTADDEAWSAELPGGGISSPVAWGDKVFLLAADPKTAVRHVLAYQLSSGKQLWDKTFDSVPHHLHKRNRFAASTPCCDEKFVYVAWSEPQHTTVSCLTHEGELVWQRDLGRWQSQHGFATSPMLYEDFVIVFDSQQARQLKPGETAGESKMVALNRQTGQMVWETPLETTNVCYGTPCVYQPAGGAAQLVDANTGNGLFGLDPKTGKMLWNLKVFRSRCCSSPVVAGDLVLGSAGSGGGGNHLVAVRPGEEPTEAYRVERGAPYVPTSVVVGDMAFLCGDNGVATCIDVNSGEPYWTRRIGGTISSSPIVVGDKLLTIDMDGKATVLRAGKKFEKLGTADLHGNVQATPAYTQGYLLLRSENRLTAIGPKRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZZ3</accession>
    <name>A0A518IZZ3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_46870</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021860239" evidence="1">
        <location>
            <begin position="22"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="296" mass="31437" checksum="3004DF936920E6D2" modified="2019-10-16" version="1" precursor="true">MLIRTLLIAVSIACLHSAAIARDLVIDNVSGSDYQNDRGLVAGSPSFGPYRTIMRALLVAQPGDSIVLTKTGVPYRECISLNGRNHSGSPSYPFRIVGNGAVLDGSTTPRPDGWEIVNGNLYRYIPPRPGYGQLMLAGRALPRFVSPDGDLSSMPGGEWAHQNGRIFYRPPAGKSPLDEALEITSEAVGITLYDVEHVVITDLTIRGYRLDGINAHDKANEVQLIGIAARHNGRSGISVGGSSSVTIGASLCELNGVAQLRTEGQSHTYLANVDLAEGVGTPLANEGGNVLRLPKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J015</accession>
    <name>A0A518J015_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_47030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="116" mass="12753" checksum="B461D827FD20BDB0" modified="2019-10-16" version="1">MMMLRQPTDQNADVERSTDESASLPRAVSLKADRDVEPAERQFPAELQAGNLEQSPLREAPRAVAAAPQQVPSVPLSQVHDVFFDPGDVFIGRSARSANPTRRTHPPRIQANPFAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J033</accession>
    <name>A0A518J033_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sulfotransferase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_47220</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008146">
        <property type="term" value="F:sulfotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000863">
        <property type="entry name" value="Sulfotransferase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00685">
        <property type="entry name" value="Sulfotransfer_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Sulfotransfer_1" evidence="1">
        <location>
            <begin position="5"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="286" mass="32885" checksum="F3E13652D03F1E06" modified="2019-10-16" version="1">MKSLVWLASYPKSGGELVEELFAQYQLTSGTQDDRLQWIFHSTKCASRRQAYERAAGRKGLSNQEIDELREAVQIDLSNRVRPPVLIKTHNARVQHNGFPIIRRELTLGAIYIVRNPLDVVDSVADHWGVDHDRAIAMMNDRNLTIGGPKQDLVTQYLESWSGHVTSWIDQRAFPVHVVCYEDLLARTEITFRNVLTFLGWDPDPERIERAIAETDFRRLQKREKEAGFGERSNKSTSGTFFRSGKAERWRDTLTEVQVNRVVEANADVMERFCYQTSVAARQSMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0D2</accession>
    <name>A0A518J0D2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ABC-2 family transporter protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_48130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
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            <strain evidence="2 3">Mal33</strain>
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            <end position="48"/>
        </location>
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    </feature>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="QDV58788.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
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    </evidence>
    <sequence length="628" mass="69412" checksum="0D09CDEEE487927D" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0J0</accession>
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
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                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
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                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">Mal33</strain>
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    <feature type="transmembrane region" description="Helical" evidence="1">
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        <source>
            <dbReference type="SAM" id="Phobius"/>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
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</entry>
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        </lineage>
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
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                <person name="Kallscheuer N."/>
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                <person name="Lage O.M."/>
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                <person name="Ovreas L."/>
                <person name="Rohde M."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">Mal33</strain>
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    </reference>
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</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0Q3</accession>
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    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 5">Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 5">
            <text>ATP + CoA + succinate = ADP + phosphate + succinyl-CoA</text>
            <dbReference type="Rhea" id="RHEA:17661"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.2.1.5"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 5">Carbohydrate metabolism; tricarboxylic acid cycle; succinate from succinyl-CoA (ligase route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 5">Heterotetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the succinate/malate CoA ligase alpha subunit family.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.5" evidence="2"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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    </dbReference>
    <dbReference type="HAMAP" id="MF_01988">
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Citrt_syn/SCS-alpha_CS"/>
    </dbReference>
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        <property type="entry name" value="CoA-bd"/>
    </dbReference>
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        <property type="entry name" value="CoA_lig_alpha"/>
    </dbReference>
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        <property type="entry name" value="CoA_ligase"/>
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        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016102">
        <property type="entry name" value="Succinyl-CoA_synth-like"/>
    </dbReference>
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        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00549">
        <property type="entry name" value="Ligase_CoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001553">
        <property type="entry name" value="SucCS_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00881">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52210">
        <property type="entry name" value="SSF52210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01019">
        <property type="entry name" value="sucCoAalpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01216">
        <property type="entry name" value="SUCCINYL_COA_LIG_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00399">
        <property type="entry name" value="SUCCINYL_COA_LIG_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="1 2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="CoA_binding" evidence="6">
        <location>
            <begin position="4"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Coenzyme A binding" evidence="2">
        <location>
            <begin position="17"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Coenzyme A binding" evidence="2">
        <location>
            <begin position="96"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-phosphohistidine intermediate" evidence="2 3">
        <location>
            <position position="247"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared with subunit beta</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR001553-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV58920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="293" mass="29778" checksum="000B865E0039DD24" modified="2019-10-16" version="1">MSILIDKNTRVICQGITGGAGTFHTKGCKEYGTQMVGGVTPGKSGQDVDGVPVFDTVGEAVEKTGANATMIFVPPPFAADAILEAIDAGIEVIAAITEGIPVLDMVRVFKAAKASGSVLIGPNCPGLITPGECKIGIMPGYIHQPGNIGIMSRSGTLTYEAVWQTTNLGLGQSTCVGLGGDPIVGTSFIDLLARFQEDPQTEAILMMGEIGGSAEEEAAAFVKENVTKPVAAFIAGRTAPPGKRMGHAGAIITGGKGTATEKVAALEDAGIVVAASPADMGAAVVEAMKRHGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0S3</accession>
    <name>A0A518J0S3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Na(+)/H(+) antiporter subunit F</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">mrpF_2</name>
        <name evidence="9" type="ORF">Mal33_49710</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015075">
        <property type="term" value="F:ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007208">
        <property type="entry name" value="MrpF/PhaF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34702">
        <property type="entry name" value="PTHR34702"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04066">
        <property type="entry name" value="MrpF_PhaF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="25"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="55"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="80"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV58946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="109" mass="11780" checksum="72EC3D347AEAA2F6" modified="2019-10-16" version="1">MMLDCLVNFATATNPMLAATAWVDLTAQVSMVVLVIALFLAFLRLILGPSLPDRVVAIDLVAVLLVGLIAVSAVETGEVIFLRVAMVVALFNFIGTIGFCWYLQRGPRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0T0</accession>
    <name>A0A518J0T0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Na(+)/H(+) antiporter subunit E</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">mrpE</name>
        <name evidence="9" type="ORF">Mal33_49720</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002758">
        <property type="entry name" value="Cation_antiport_E"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34584">
        <property type="entry name" value="PTHR34584"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01899">
        <property type="entry name" value="MNHE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF019239">
        <property type="entry name" value="MrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="27"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV58947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="157" mass="17835" checksum="5DCF3B39DC833A1B" modified="2019-10-16" version="1">MIYFFFNIFLALVWALANGQISLSNLGIGFLLGYAVLWFSKPLLGPTGYFRRLPVALRFVVFFFWQLVLSNLRVAYDVITPPLYMRPGIVAVPLDAKTDQEITLLANLITLTPGTLSLNLSEDRSTLYVHAMFVDSPNSVRDSIKNGFERRLLELMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0V1</accession>
    <name>A0A518J0V1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Arylsulfatase</fullName>
            <ecNumber evidence="3">3.1.6.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_49870</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="PTM">
        <text evidence="1">The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.</text>
    </comment>
    <dbReference type="EC" id="3.1.6.1" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004065">
        <property type="term" value="F:arylsulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sulfatase" evidence="2">
        <location>
            <begin position="23"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="modified residue" description="3-oxoalanine (Cys)" evidence="1">
        <location>
            <position position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR600917-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="476" mass="54197" checksum="419BAD43D0DE95BA" modified="2019-10-16" version="1">MLVAFCAAALTGFCHGDARAERPNILWIYVDDMSDWMGCYGDPIAVTPNIDRLAEGGVLFQHAYMPAPVCSTTRSALITGTMQTTHGLHQHRTMIKNPLPDDLTTIPELFRQAGYLTFNEAKDDYNFVRDRETMYSPEFQRPSRKQVNSHMLGRDASWLKQLKGQPFFGQIQLKGGKFGGETGAKFPTESRFDTDRVSVPPQYPEHPVFRDAIARHYEQIAETDAQVGAILDALKAYDMWDNTAVFFFTDHGSPLPRAKQFLYEDGLKVPLIVHWPTGNDVITRRGNVRADLVSGIDITASTLGLAGIAIPEFMEGVDLFAEDYASQQYVISARDRMGNAIDRIRTVRSQRFRYIRNYKLDRALFQPQYRDKYATFATLQKLLRLGKLSPIQASYFDAEHRPAEELYDLVDDPHQINNLAENPEFRSVLESHRQHLADWEEATDDKGRYPESRESLKRVFESSAGKCVSPEYDFLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1B7</accession>
    <name>A0A518J1B7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Probable transcriptional regulatory protein Mal33_51310</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">yeeN</name>
        <name evidence="5" type="ORF">Mal33_51310</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the TACO1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.980">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00693">
        <property type="entry name" value="Transcrip_reg_TACO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017856">
        <property type="entry name" value="Integrase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002876">
        <property type="entry name" value="Transcrip_reg_TACO1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026564">
        <property type="entry name" value="Transcrip_reg_TACO1-like_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029072">
        <property type="entry name" value="YebC-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12532">
        <property type="entry name" value="PTHR12532"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01709">
        <property type="entry name" value="Transcrip_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75625">
        <property type="entry name" value="SSF75625"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 4" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV59105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="241" mass="26217" checksum="DA652777BF10AC29" modified="2019-10-16" version="1">MGRSFEVRKVSMAKTAGQKSKLYSKYGKQLYVLAKNSGADPTANPSLRSLIDKAKREQVPAHVIEKALEKASGGGGEDFSLARYEGYGPGGCAVIVDCLTDNNNRTITDVRNCFTKTSSKLGAPGSVAHSFDHLAVLRFPGDSADQVLEILLGADVDVVDVECEDGQITVFAPATEFNNAKQAMLEANPELEFDVDEITFVAQTNTDISPDDLPMFEKFMNMLNDCDDVQDVYHNAILPKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1D1</accession>
    <name>A0A518J1D1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acetylxylan esterase</fullName>
            <ecNumber evidence="3">3.1.1.72</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">axeA1_2</name>
        <name evidence="3" type="ORF">Mal33_51820</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.1.72" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046555">
        <property type="term" value="F:acetylxylan esterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021846285" evidence="1">
        <location>
            <begin position="24"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="domain" description="Abhydrolase_3" evidence="2">
        <location>
            <begin position="104"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV59154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="288" mass="31035" checksum="BCB4E2FAAD3130D1" modified="2019-10-16" version="1" precursor="true">MTRLFSFGLVLSLSVSGFVQTLAAESPAKIPLWADGAPGSVDRMNEPEKVEGTNVSNVHHPSITPYLPAEGEATGTAILIAPGGGHSKLCLGHEGDALAEWFAEHGIAAFVMRYRLCREPDSHYTLEGHAMDDTRRAIRTVRANAKAWKIDPNRIGIVGFSAGGELAAYAAMHPEAGDPKSDDPIERVSSRPDFQGLIYPGKSATFTVEPGMPPAFIAFGYHDREDIAVGMANVYLQYKAAGVPCEMHVYSNAGHGFGFRPGTTTAAGDWPKRLCEWLVDTKLLTKQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1D7</accession>
    <name>A0A518J1D7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_51880</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021971714" evidence="2">
        <location>
            <begin position="28"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV59160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="137" mass="15268" checksum="C90141CFD437EE63" modified="2019-10-16" version="1" precursor="true">MVPRMFPIFLTLVTLVSLACAPSSVMAQPPKIEADGPSVFSKLNPLNWSAPKMPSIKFPTVSQKKKVTKSKQPGFWSSVGTSTRSAWDKTTDFLNPFDDKPKKKKKSESFLSKLTKPAEEPRPISTVGDFLQQKHPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1M3</accession>
    <name>A0A518J1M3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_52600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025738">
        <property type="entry name" value="BatD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40940">
        <property type="entry name" value="PTHR40940"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021810020" evidence="3">
        <location>
            <begin position="28"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="292"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="401"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV59232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="424" mass="46159" checksum="57D0A3F7FF21D18B" modified="2019-10-16" version="1" precursor="true">MRVPRGMMFGLAVIALCAVTFAAAAPAADDDPVSIDVPNKEAWMGQRLPIFVQLRGNGPFVGAASFSIPEIPRALLVKVGSPVVSSEEKGDTSWFMQTHEFALFSQAAGKVTIPAFEVRFTHRDGFTGPQQEHVEQVPATDLQIKRPVGLPESVFLVTTEKLEITESWTPEPGSAKQGDVFRRTIAQTAQQTSGMALAPPPTTAPEGISVYVGKPTVDDKTQRGEFSGTRSDTITYMLKGAGTLTIPGIKYIWWNPKSEEFGTKTLPAVTFEVAAAPKPAPPPPPPPSRMRIALAAFLLFSLLGVAIWQFDRIRSWTKTLWRRLNPADRVAARHLIRACHRNDAAAAEAAWTDWQNTQPASYQPSAELFATAAELHRTRYGQRAEASAAWQGQPLAQAFRKATATSSATQNQQPPLPPLNPRST</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1U4</accession>
    <name>A0A518J1U4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Spore protein SP21</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">hspA</name>
        <name evidence="4" type="ORF">Mal33_53380</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the small heat shock protein (HSP20) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002068">
        <property type="entry name" value="A-crystallin/Hsp20_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045045">
        <property type="entry name" value="RTM2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43670">
        <property type="entry name" value="PTHR43670"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00011">
        <property type="entry name" value="HSP20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="SSF49764"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01031">
        <property type="entry name" value="SHSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SHSP" evidence="3">
        <location>
            <begin position="36"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS01031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV59310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="147" mass="16575" checksum="134355BFF1AC8C8B" modified="2019-10-16" version="1">MSSYNMTRALVPSGFGISGREMEELFDRLFHPGSSPAANRWTPPASVWETGEQIHLEMELAGVAREDIDVSFEDGLLKISAKRPQPDTTDRSYLHDERAWGEMTRTMRVADSVDPDSIEASFQKGLLHIQLCKRAEVLPKRIEIKTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1Z1</accession>
    <name>A0A518J1Z1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ferredoxin--NADP(+) reductase</fullName>
            <ecNumber evidence="4">1.18.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">fpr</name>
        <name evidence="7" type="ORF">Mal33_53810</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H(+) + NADP(+) + 2 reduced [2Fe-2S]-[ferredoxin] = NADPH + 2 oxidized [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:20125"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.18.1.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ferredoxin--NADP reductase type 1 family.</text>
    </comment>
    <dbReference type="EC" id="1.18.1.2" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004324">
        <property type="term" value="F:ferredoxin-NADP+ reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06195">
        <property type="entry name" value="FNR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033892">
        <property type="entry name" value="FNR_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="SSF52343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="6">
        <location>
            <begin position="19"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV59353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="316" mass="35621" checksum="D62A038AEC802B67" modified="2019-10-16" version="1">MNKIVVTPPTQAEIETLRRTTYNATLIQRIDIHEDLALFRIKPDTQTVPFQPGQYLTLGLGYWEPRVQPTQEELLEPKKLRKVVKRAYSISCPMLDGLEQLAPCSELDYYEFYVTLVRRADAPPALTPRLFHMQEGDRIFASPRIVGTYVLSGVQPDEDVVFFATGTGEAPHNAMSAELLSRGHRGRIVSATCVRLRRDLGYLAAQMRLSTKYTNYQYLHFTTREAENTNPGFPGFVGKQHLQQVVESGIFEAAAGMKLDPERTHVFLCGNPAMIGYQPPGAPPLSSPGMLQVLKKRGFHDHGEDGPGQIRFEKYW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J266</accession>
    <name>A0A518J266_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Macrolide export protein MacA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">macA_5</name>
        <name evidence="2" type="ORF">Mal33_54630</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="483" mass="54113" checksum="D03CD7DFEABCC761" modified="2019-10-16" version="1">MQMQNSKRQRRGSASTTIFAATLGMFLVCGVVGQFFGSMVDSVKGFFVEAPKPVYLTTTATMEPFVHTVLERGEVESSSNIEVRCEVNRRSGSAGTNIIEIVPEGTWVEAGDFLVRLDDSALQTQLIQQQIVCSNSESAVIEAQAKVDSTKLELSEYEEGTFKEKLAQQQSEVFVAQENKRRAEEYLDYSKRLAERGYIPEAQLEADTFAVEKARNELGVAETKLAVLNTFTKEKMLTQLRAEIRTAESRLQSRTKTWELDKVQLEEIEDQIEKCRIWAPVAGQVVYANNQTRSANKIMIEEGMPVRERQTIINLPDPKKMRVKTLVHESRIGHVRPGLTAELMLDAMPDLSLTGKVTTVSEYPLPAISVYMSHVKEYVVEVEITDPPRDLRPGMTAEVNILVQRIDQALQVPIEAVIEREGQYFCALPNEDGTLETREVVVGTTNETNLVIESGLSANEEVVLNVRTEQVMEQMDLPSLETS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IM01</accession>
    <name>A0A518IM01_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_00340</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="196" mass="22907" checksum="0998358ED14C950C" modified="2019-10-16" version="1">MQQMRSIGQRATERRCREGSPTRLPRRTSGDVRAEPAGLIRRPVGREVARSRGSPQRQPHRELDPTTEPIDRSAAADRGSSSRRMDWLTTGRSDNHRHHGGDAIRHRRRRQRLIHPPANHPHWEDHQRDDGNYENRRSLQRDGGHARRRWRHAAMRVRAPRQQQDTASSVEWVGTAKSWTTFVFFSIRVEFDPTKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMD5</accession>
    <name>A0A518IMD5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Mannose-6-phosphate isomerase</fullName>
            <ecNumber evidence="3">5.3.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">yvyI</name>
        <name evidence="6" type="ORF">Mal33_01830</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>D-mannose 6-phosphate = D-fructose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:12356"/>
            <dbReference type="ChEBI" id="CHEBI:58735"/>
            <dbReference type="ChEBI" id="CHEBI:61527"/>
            <dbReference type="EC" id="5.3.1.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="4">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mannose-6-phosphate isomerase type 1 family.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.8" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004476">
        <property type="term" value="F:mannose-6-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001250">
        <property type="entry name" value="Man6P_Isoase-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014628">
        <property type="entry name" value="Man6P_isomerase_Firm_short"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01238">
        <property type="entry name" value="PMI_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036894">
        <property type="entry name" value="PMI_Firm_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="active site" evidence="5">
        <location>
            <position position="196"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR036894-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR036894-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV54233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="322" mass="34333" checksum="51D28AEB13D93CC5" modified="2019-10-16" version="1">MQAPLRFQPLFREYIWGARRLGSVLGKPIGDAPRYAESWEIVDHGEDQSIVADGPLAGQSLSDLLRTSAADLLGAELACDRFPLLLKYLDCDRVLSVQVHPDDAYAQKMTPPDLGKTEAWYIIAADPGSLIYAGLKAGVGPEELRAACAAGRTEDVLHTLQPSAGDCVFIPAGTVHALGSGLLVAEIQQSSDTTFRLFDWNRVDDAGNSRPLHVSQAIEVTDYGRGPVEFQKPQSLATGGQRLVGCDKFFLDRYCGGSQHEVGGDGRFRILTVVTGGASVAWGDGQSMPLPLGQTVLLPASLGQVQLLGGDADTVVLCMGMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IME9</accession>
    <name>A0A518IME9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_01950</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="55" mass="6192" checksum="8D354AEE7EB7B8E5" modified="2019-10-16" version="1">MGEGRGRTNPAPEIAVAVQSSSVQLSFNEDVAISCRTIYFNKPRMEVKYFVLLRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMG4</accession>
    <name>A0A518IMG4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 14">Undecaprenyl-diphosphatase</fullName>
            <ecNumber evidence="4 14">3.6.1.27</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13 14">Bacitracin resistance protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12 14">Undecaprenyl pyrophosphate phosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14 15" type="primary">uppP</name>
        <name evidence="15" type="ORF">Mal33_02260</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 14">
            <text>di-trans,octa-cis-undecaprenyl diphosphate + H2O = di-trans,octa-cis-undecaprenyl phosphate + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:28094"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58405"/>
            <dbReference type="ChEBI" id="CHEBI:60392"/>
            <dbReference type="EC" id="3.6.1.27"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="14">Cell membrane</location>
            <topology evidence="14">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="14">Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the UppP family.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.27" evidence="4 14"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050380">
        <property type="term" value="F:undecaprenyl-diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016311">
        <property type="term" value="P:dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01006">
        <property type="entry name" value="Undec_diphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003824">
        <property type="entry name" value="UppP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30622">
        <property type="entry name" value="PTHR30622"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02673">
        <property type="entry name" value="BacA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 14" id="KW-0046">Antibiotic resistance</keyword>
    <keyword evidence="6 14" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="14" id="KW-0133">Cell shape</keyword>
    <keyword evidence="14" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="8 14 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="71"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="101"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="170"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="203"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="233"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00021581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00032707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00032932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="QDV54276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="253" mass="27685" checksum="E5898CA787E8727B" modified="2019-10-16" version="1">MWEMVLLAVIQGIAEFLPISSSGHLVIFGELLGITEESATVNIVLHAGTLASILVVYWRRILDMLTSDRRVIPLLVIGTIPAGIAGVIIKTQFKHLLESPLIAGCMLLVTGGLLLLLKYLPTRDATYQSLSWRKAFEIGTFQAFALMPGISRSGSTIVGGRMLGLSNEDAVTFSFLLAIPAILGATVLEMKDLAQSDLTMDRMAPLLVGAVVAFLVGIFALRWLIAWSRRGRLHLFAWWCIPMGIGTILWQLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMJ5</accession>
    <name>A0A518IMJ5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Arylsulfatase</fullName>
            <ecNumber evidence="3">3.1.6.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">atsA_2</name>
        <name evidence="3" type="ORF">Mal33_02430</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="PTM">
        <text evidence="1">The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.</text>
    </comment>
    <dbReference type="EC" id="3.1.6.1" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004065">
        <property type="term" value="F:arylsulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sulfatase" evidence="2">
        <location>
            <begin position="50"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="modified residue" description="3-oxoalanine (Cys)" evidence="1">
        <location>
            <position position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR600917-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="469" mass="51940" checksum="99F89EC45A905178" modified="2019-10-16" version="1">MTRPLENRIHQPSATRHCSSRMPWACILLAILIGQTTLATSVRADEADRPNLIYIMVDDLGYGDLGCFGQQTIKTPNIDRLAAEGMKLTSHYSGNTVCRPSRLSLWTGMHAGHTAIDSNAPYVLKESDVTVAELLQQAGYTTGGIGKWALGNTENSGHPNRQGFDFWMGYLDQGEAHNYYPAKLWRNDQKVPLPGNVISDAPLARGRVSSKRTTYSHDVMTEEMLDFVRGQGDKPFLMHIHWTIPHANNEGGRVNKDGMEVPDYGIYADRDWPNPEKGFAAMITRMDGDVGRLMALLKEKQIDDNTLVVFTSDNGPHSEGNHKHETFDSNGPLRGYKRDLYEGGIRMPTIARWPGKIAAGSTSDQLLAHYDWLPTACELAGVDPPAGVDGISFAATLLGQSQRPHEYLFWSYGDKKAARIGNWKAVIPGKNKPLELYDLANDIGETKNIADQHPDVVEKMKQAIAEALE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IN03</accession>
    <name>A0A518IN03_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_04190</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="162"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="194" mass="21680" checksum="394A0039EA41F64A" modified="2019-10-16" version="1">MKPRPATWARQIAGPSARQRSVGSDAWKTSQPPTSHIAPVPIPKGSKKVAGGLSAANTTGIKRPLSELRSSGRIKPGVNHPSDSADGVTPGRSNVQPHNWFSFWRLCRQNENQLRNLGLRLASQSDPRLYAATASQFEYRLATERPCHHRWRAFPRNFATPWQTSDRATNWPNPDRLENRRQQNTSNGNARSPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INA8</accession>
    <name>A0A518INA8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="10">NADH-quinone oxidoreductase subunit L</fullName>
            <ecNumber evidence="10">1.6.5.11</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">nuoL_1</name>
        <name evidence="10" type="ORF">Mal33_05210</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Membrane</location>
            <topology evidence="1 5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="1.6.5.11" evidence="10"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042773">
        <property type="term" value="P:ATP synthesis coupled electron transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001750">
        <property type="entry name" value="ND/Mrp_mem"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003945">
        <property type="entry name" value="NU5C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001516">
        <property type="entry name" value="Proton_antipo_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42829">
        <property type="entry name" value="PTHR42829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00361">
        <property type="entry name" value="Proton_antipo_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00662">
        <property type="entry name" value="Proton_antipo_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="48"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="97"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="129"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="153"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="183"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="231"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="267"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="291"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="324"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="domain" description="Proton_antipo_N" evidence="9">
        <location>
            <begin position="78"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="Proton_antipo_M" evidence="8">
        <location>
            <begin position="151"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="442"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="442"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV54566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="464" mass="51111" checksum="5AE30742C3D120D4" modified="2019-10-16" version="1">MNYLDTTFQALGTAVVASPAILLAILGLAALVNWQLSEATISRLTQAAVLFSLLPAIGILVIMLATGIRYVPIELGNWVSIPEQEFHFHLKFVFDRLSIPFLMLSCVLCGVVGAFTRRYLHREEGYRRFFLYYAVFFCGMVLSSLAGTIEALFVGWELVGLSSALLVAYFHERVNPVRNGQRVWSIYRLSDAAFLIAALMMHHLSGEGDFGGLMSSGVWPEGTAAISSTEALWVGSLLLVAAAGKSALFPFSGWLPRAMEGPTPSSAIFYGALSVHLGAFLLLRLSPILDASLTLQLMVIALGVVSAACGAVMSRVQNDIKVSLAYASLTQVGIIVVEIGLGLRYLALIHIIGHACMRTMQLLRAPTLLRDYNELENKIGTRLPHQAWAGAASLPASVQRWCYRFGYDRGFMDLALDKWIVRPFLQTFGWFDRLERRITDSISHEPSRESDRAEPHPEDLQNVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INC8</accession>
    <name>A0A518INC8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_05540</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="160" mass="17859" checksum="87D82FB43D8EFF54" modified="2019-10-16" version="1">MNLPESPDYLNSLQGGWEALGNGAPTLVALAQLCARSMVEGTRDKTPLSVEAKAILYAARNRGVIEVRGVNTAFEATARLLAVYIEEDEHRTIAFRNRERPQVTVRFFEAFCQLCRHGLVLHHLYRDFSLTDRGFAIAAKIEREEVAEALGEATEFGLHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IND9</accession>
    <name>A0A518IND9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tetratricopeptide repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_05520</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022129376" evidence="2">
        <location>
            <begin position="30"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="30"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="173"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="247" mass="27304" checksum="1F2A3F713A22C4FE" modified="2019-10-16" version="1" precursor="true">MHSFRKSQLKCPLTAAALFVLSLSGCQFAASGQNAQGVRLYEQGQYSAALQQFQQAIASDPKNPDSYYNLAATTHRLGKERNDRSLLDQSESLYNQCLDLDPSHVDCHRGLAVLLVETDRPDRAFALMRNWATSQPQLADARIELARLYQEFGEGETAQKFLEDAIHQDGNNARAWLALGQIREAAGDYQQALQDYQRSYDLNSMQPQVAERIASMNRQIVSGAGGVTASGTRLAQQSAADVSKGRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INE7</accession>
    <name>A0A518INE7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Laminin G domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_05620</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00110">
        <property type="entry name" value="LamG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006558">
        <property type="entry name" value="LamG-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001791">
        <property type="entry name" value="Laminin_G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00560">
        <property type="entry name" value="LamGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022083899" evidence="2">
        <location>
            <begin position="31"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="domain" description="LamGL" evidence="3">
        <location>
            <begin position="490"/>
            <end position="621"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV54607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="670" mass="73646" checksum="184AA201126CCDA8" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INH1</accession>
    <name>A0A518INH1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">Superoxide dismutase</fullName>
            <ecNumber evidence="2 6">1.15.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">sodA</name>
        <name evidence="9" type="ORF">Mal33_05800</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Destroys radicals which are normally produced within the cells and which are toxic to biological systems.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>2 H(+) + 2 superoxide = H2O2 + O2</text>
            <dbReference type="Rhea" id="RHEA:20696"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:18421"/>
            <dbReference type="EC" id="1.15.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the iron/manganese superoxide dismutase family.</text>
    </comment>
    <dbReference type="EC" id="1.15.1.1" evidence="2 6"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004784">
        <property type="term" value="F:superoxide dismutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.55.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001189">
        <property type="entry name" value="Mn/Fe_SOD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019833">
        <property type="entry name" value="Mn/Fe_SOD_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019832">
        <property type="entry name" value="Mn/Fe_SOD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019831">
        <property type="entry name" value="Mn/Fe_SOD_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036324">
        <property type="entry name" value="Mn/Fe_SOD_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036314">
        <property type="entry name" value="SOD_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02777">
        <property type="entry name" value="Sod_Fe_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00081">
        <property type="entry name" value="Sod_Fe_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000349">
        <property type="entry name" value="SODismutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01703">
        <property type="entry name" value="MNSODISMTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46609">
        <property type="entry name" value="SSF46609"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54719">
        <property type="entry name" value="SSF54719"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00088">
        <property type="entry name" value="SOD_MN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 6 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sod_Fe_N" evidence="7">
        <location>
            <begin position="3"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="Sod_Fe_C" evidence="8">
        <location>
            <begin position="96"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="27"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000349-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV54625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="207" mass="22064" checksum="C74679DCD373596D" modified="2019-10-16" version="1">MAYELPALPYAHDALEPHIDARTMEIHHGKHHQAYITKVNDAIAGTDLESKSIEDLISDLSAVPADKLGAVRNNGGGHANHSLFWTVMGPGCGGAPSGDLAAAIDSDLGGLEAFKTAFANAGATRFGSGWAWLYVSEGKLKVGSTANQDNPLMGEAVAGIGGTPLLGLDVWEHAYYLNYQNRRPDYINAFWEVVNWSAVADRFAAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INL7</accession>
    <name>A0A518INL7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Modulator of FtsH protease YccA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">yccA</name>
        <name evidence="6" type="ORF">Mal33_06370</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the BI1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006214">
        <property type="entry name" value="Bax_inhibitor_1-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23291">
        <property type="entry name" value="PTHR23291"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01027">
        <property type="entry name" value="Bax1-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="38"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="108"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="133"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="165"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="219"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV54681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="248" mass="26955" checksum="E503567F7671027A" modified="2019-10-16" version="1">MSSTNPYQFETGQAGMGGNMMAAFAEESARAGFIRKTYLHLAAAVLGFVGIEALLLTAVPANTMEMIVTRMVTGYGWLIVLGAFMAVSWMARRWAESGASPGMQYMGLSLYVVGQAIVFLPLLYIAMRFDPQTPVIAGMLTSIVFFGLTAFVFVTRVDLSWMGKILFMAGLVAMGAIVCGIMFGFSLGIFFSAIMVAVASGYILYDTSNVLHHYRTDQYVAASLALFASVALLFWYILQLVMSFSSND</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INZ4</accession>
    <name>A0A518INZ4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_07740</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="103" mass="11241" checksum="EE8D2105F65F36A7" modified="2019-10-16" version="1">MPFPIALPNVSWHAAVDYNLGVCRLESKQAVGGVMGWQTTRYLDARWQALFGVDGEAVPAAASLPDVPRMLWLPTVACGNCRFEKKGGVRSDGSAPENRIPNW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP49</accession>
    <name>A0A518IP49_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Signal recognition particle protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ffh</name>
        <name evidence="9" type="ORF">Mal33_08340</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GTP-binding SRP family. SRP54 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048500">
        <property type="term" value="C:signal recognition particle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008312">
        <property type="term" value="F:7S RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006614">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036891">
        <property type="entry name" value="Signal_recog_part_SRP54_M_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013822">
        <property type="entry name" value="Signal_recog_particl_SRP54_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004125">
        <property type="entry name" value="Signal_recog_particle_SRP54_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004780">
        <property type="entry name" value="SRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022941">
        <property type="entry name" value="SRP54"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000897">
        <property type="entry name" value="SRP54_GTPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042101">
        <property type="entry name" value="SRP54_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11564">
        <property type="entry name" value="PTHR11564"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11564:SF7">
        <property type="entry name" value="PTHR11564:SF7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00448">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02881">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02978">
        <property type="entry name" value="SRP_SPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00962">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00963">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47446">
        <property type="entry name" value="SSF47446"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00959">
        <property type="entry name" value="ffh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00300">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0733">Signal recognition particle</keyword>
    <feature type="domain" description="SRP54" evidence="8">
        <location>
            <begin position="268"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="446"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="464"/>
            <end position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS00300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV54869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="490" mass="53273" checksum="B6ED18F5B8561416" modified="2019-10-16" version="1">MFESLSDGLQSAFKSLRGKGKLTEANMRDGLKLVEQSMLEADVSYSVVQSFMQHVTEKATGRRVLMSLRPGEELVKIVYDELVDILGPVDSSLHLKGDGITVIMMCGLQGSGKTTTCGKLSQLLKEENIKPLLVAADLQRPAAIEQLRVIGRQLDVPVYAEDGASDPVKVCQAGVKQAQQQGARVVILDTAGRLAIDKELMDQLARIDKRVKPDQVYLVVDGMTGQDAVNSAGAFNEALELDGVVMTKLDGDARGGALLSVKHVTGVPIKFIGTGEHFDALEPFRPEGMTGRILQMGDMVAAAREAHRIVDESQREELEEKMKSGEMTLDDFKGLMEKVAKPGLMGKMMGLMPGMGQLKDLMNSEEAAGGIKQTIGAINSMTLEERRNPKIIDISRRTRIAKGAGVQASAITQLVKQFEQMKPIMQAMAGGGVGDRMQLMRQLQSSGALDGSNPGALKMKKSTGKRLSAAERAKQKKQREKELRKLRRSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP53</accession>
    <name>A0A518IP53_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Zinc metalloprotease Rip3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">rip3_1</name>
        <name evidence="10" type="ORF">Mal33_08310</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase M50B family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008915">
        <property type="entry name" value="Peptidase_M50"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02163">
        <property type="entry name" value="Peptidase_M50"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="10" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="95"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="122"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="153"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="178"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M50" evidence="9">
        <location>
            <begin position="43"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M50" evidence="9">
        <location>
            <begin position="123"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="222"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV54866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="261" mass="28039" checksum="74B9FFBB746709C1" modified="2019-10-16" version="1">MFNWKLGTVAGIPINVHGTFWLLPLFVLLTAMPDGSLPMRLAILFSVFGCVLLHELGHAMMARLFGVGTRDITLYPIGGVARLDRMPRSPLAEGAIALAGPAVNLVIAALLVPLLLLASGSIASTFLMSMIYINIALIVFNMLPVFPMDGGRVFRAFLGAFVPYVRATQIAATVGQVLAIGMGVVGLFTDGMLIFIAIFAYFAARAELAMVQREAMAGEPQTAYESWSEPQPRPQAAKASTGPARRSYVLLDRNGHKIASY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPF4</accession>
    <name>A0A518IPF4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FlgN protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_09530</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044780">
        <property type="term" value="P:bacterial-type flagellum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007809">
        <property type="entry name" value="FlgN-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036679">
        <property type="entry name" value="FlgN-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05130">
        <property type="entry name" value="FlgN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140566">
        <property type="entry name" value="SSF140566"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="132"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="43"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="137"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="152" mass="16804" checksum="19037C6B30A76DD2" modified="2019-10-16" version="1">MTSHSPAEAALRLSQLVDDKFRLLGVLIEKGKQQQQQITAGDATALLQLLAEKQTLIEELQRLQDEIAALQSRGDLAWASPEARARCQSVAGQCNALGQLVLELEATCERHATTQRDAMAKQIHDFSNFNSRSSDSYSLDDETRLAEFDESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPG0</accession>
    <name>A0A518IPG0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Gamma-glutamyl phosphate reductase</fullName>
            <shortName evidence="7">GPR</shortName>
            <ecNumber evidence="7">1.2.1.41</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Glutamate-5-semialdehyde dehydrogenase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Glutamyl-gamma-semialdehyde dehydrogenase</fullName>
            <shortName evidence="7">GSA dehydrogenase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">proA_1</name>
        <name evidence="7" type="synonym">proA</name>
        <name evidence="9" type="ORF">Mal33_09320</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>L-glutamate 5-semialdehyde + NADP(+) + phosphate = H(+) + L-glutamyl 5-phosphate + NADPH</text>
            <dbReference type="Rhea" id="RHEA:19541"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58066"/>
            <dbReference type="ChEBI" id="CHEBI:58274"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.2.1.41"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-glutamate: step 2/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the gamma-glutamyl phosphate reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.41" evidence="7"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00098">
        <property type="reaction ID" value="UER00360"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004350">
        <property type="term" value="F:glutamate-5-semialdehyde dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055129">
        <property type="term" value="P:L-proline biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd07079">
        <property type="entry name" value="ALDH_F18-19_ProA-GPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00412">
        <property type="entry name" value="ProA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020593">
        <property type="entry name" value="G-glutamylP_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012134">
        <property type="entry name" value="Glu-5-SA_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000965">
        <property type="entry name" value="GPR_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000151">
        <property type="entry name" value="GPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00407">
        <property type="entry name" value="proA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01223">
        <property type="entry name" value="PROA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7" id="KW-0521">NADP</keyword>
    <keyword evidence="6 7 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 7" id="KW-0641">Proline biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="8">
        <location>
            <begin position="17"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="Aldedh" evidence="8">
        <location>
            <begin position="316"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV54964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="424" mass="45578" checksum="BE196A087AE91DBB" modified="2019-10-16" version="1">MTTAETPSLKSYCLDVAERAHRASRQLSTLSTEVKNRWLLQSADALLQHEAEIQKTNTLDLQAAAGFGLTDAEVDRLRLTSDRIAAIAKGLREIAALPDPIGQVIEGFRRPNGLQIIKRRVPLGVVFFIYESRPNVTADAAAICVKSGNAVILRGGKEAAHSSAAIVEILNKTAAEVGLPADAVQLVSTADRDAVGHFLGMHELIDVTIPRGGESLIRRVASEATMPVIKHYDGNCHVYVDRDANLDQAVEIAVNSKCHRMGVCNACESLLVHRDVADTFLPQIAAALAQHDVEIVGDPQTCQRVPAASAATEADWSTEYLGPKISVRVVDDLESAIEHINRYGSHHTDAIVTKDLAASERFTDAIDSAAVMVNASTRFNDGGEFGLGAEIGISTDKFHARGPCGLTELTSYKYVVNGQGQVRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPG5</accession>
    <name>A0A518IPG5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 20">Methionine synthase</fullName>
            <ecNumber evidence="6 20">2.1.1.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="19 20">5-methyltetrahydrofolate--homocysteine methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="30" type="primary">metH</name>
        <name evidence="30" type="ORF">Mal33_09260</name>
    </gene>
    <organism evidence="30 31">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="30 31" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="30 31">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="18 20">Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 20">
            <text>(6S)-5-methyl-5,6,7,8-tetrahydrofolate + L-homocysteine = (6S)-5,6,7,8-tetrahydrofolate + L-methionine</text>
            <dbReference type="Rhea" id="RHEA:11172"/>
            <dbReference type="ChEBI" id="CHEBI:18608"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:58199"/>
            <dbReference type="EC" id="2.1.1.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 20 23">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3 20 22">
            <name>methylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:28115"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4 20">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-methionine from L-homocysteine (MetH route): step 1/1.</text>
    </comment>
    <comment type="domain">
        <text evidence="20">Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the vitamin-B12 dependent methionine synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.13" evidence="6 20"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00051">
        <property type="reaction ID" value="UER00081"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008705">
        <property type="term" value="F:methionine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042558">
        <property type="term" value="P:pteridine-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02069">
        <property type="entry name" value="methionine_synthase_B12_BD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1240.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.196.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003759">
        <property type="entry name" value="Cbl-bd_cap"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006158">
        <property type="entry name" value="Cobalamin-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036724">
        <property type="entry name" value="Cobalamin-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011005">
        <property type="entry name" value="Dihydropteroate_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003726">
        <property type="entry name" value="HCY_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036589">
        <property type="entry name" value="HCY_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033706">
        <property type="entry name" value="Met_synthase_B12-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011822">
        <property type="entry name" value="MetH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036594">
        <property type="entry name" value="Meth_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000489">
        <property type="entry name" value="Pterin-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004223">
        <property type="entry name" value="VitB12-dep_Met_synth_activ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037010">
        <property type="entry name" value="VitB12-dep_Met_synth_activ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02310">
        <property type="entry name" value="B12-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02607">
        <property type="entry name" value="B12-binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02965">
        <property type="entry name" value="Met_synt_B12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00809">
        <property type="entry name" value="Pterin_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02574">
        <property type="entry name" value="S-methyl_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000381">
        <property type="entry name" value="MetH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01018">
        <property type="entry name" value="B12-binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47644">
        <property type="entry name" value="SSF47644"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51717">
        <property type="entry name" value="SSF51717"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52242">
        <property type="entry name" value="SSF52242"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56507">
        <property type="entry name" value="SSF56507"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82282">
        <property type="entry name" value="SSF82282"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02082">
        <property type="entry name" value="metH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50974">
        <property type="entry name" value="ADOMET_ACTIVATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51332">
        <property type="entry name" value="B12_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51337">
        <property type="entry name" value="B12_BINDING_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50970">
        <property type="entry name" value="HCY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50972">
        <property type="entry name" value="PTERIN_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 20" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10 20 22" id="KW-0846">Cobalamin</keyword>
    <keyword evidence="17 20 21" id="KW-0170">Cobalt</keyword>
    <keyword evidence="13 20 21" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16 20" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="8 20 24" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="31" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0677">Repeat</keyword>
    <keyword evidence="12 20 22" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="11 20 24" id="KW-0808">Transferase</keyword>
    <keyword evidence="15 20 21" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Hcy-binding" evidence="25">
        <location>
            <begin position="5"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="domain" description="Pterin-binding" evidence="26">
        <location>
            <begin position="357"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="domain" description="B12-binding N-terminal" evidence="29">
        <location>
            <begin position="649"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="domain" description="B12-binding" evidence="28">
        <location>
            <begin position="750"/>
            <end position="885"/>
        </location>
    </feature>
    <feature type="domain" description="AdoMet activation" evidence="27">
        <location>
            <begin position="899"/>
            <end position="1230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Methylcob(III)alamin binding" evidence="22">
        <location>
            <begin position="760"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="22">
        <location>
            <begin position="1192"/>
            <end position="1193"/>
        </location>
    </feature>
    <feature type="binding site" evidence="21 23">
        <location>
            <position position="248"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="21 23">
        <location>
            <position position="311"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="21 23">
        <location>
            <position position="312"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="22">
        <location>
            <position position="693"/>
        </location>
        <ligand>
            <name>methylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:28115"/>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="21">
        <location>
            <position position="763"/>
        </location>
        <ligand>
            <name>methylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:28115"/>
        </ligand>
        <ligandPart>
            <name>Co</name>
            <dbReference type="ChEBI" id="CHEBI:27638"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="22">
        <location>
            <position position="808"/>
        </location>
        <ligand>
            <name>methylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:28115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="22">
        <location>
            <position position="812"/>
        </location>
        <ligand>
            <name>methylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:28115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="22">
        <location>
            <position position="864"/>
        </location>
        <ligand>
            <name>methylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:28115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="22">
        <location>
            <position position="949"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="22">
        <location>
            <position position="1137"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00025552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00031040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="PIRNR" id="PIRNR000381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="PIRSR" id="PIRSR000381-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="25">
        <source>
            <dbReference type="PROSITE" id="PS50970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="26">
        <source>
            <dbReference type="PROSITE" id="PS50972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="27">
        <source>
            <dbReference type="PROSITE" id="PS50974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="28">
        <source>
            <dbReference type="PROSITE" id="PS51332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="29">
        <source>
            <dbReference type="PROSITE" id="PS51337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="30">
        <source>
            <dbReference type="EMBL" id="QDV54960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="31">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1230" mass="136047" checksum="665F70321BCFAC39" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPJ3</accession>
    <name>A0A518IPJ3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">L-lactate dehydrogenase operon regulatory protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">lldR</name>
        <name evidence="5" type="ORF">Mal33_09760</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
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            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="evidence" value="ECO:0007669"/>
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        <property type="entry name" value="TF_FadR/GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
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    </dbReference>
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    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="4">
        <location>
            <begin position="9"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
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    </evidence>
    <sequence length="241" mass="27184" checksum="56D9257D36F19F0B" modified="2019-10-16" version="1">MQLTPVPRRSSVDEVVERIRHEIESKGLSAGDRLPGEMELIKQLEVSRPVLREALARLRGLGLVEIQRGNGTFVAETDSLTSCVRMLRSAVTISPRELLSYTELRTAIEIQAVRQVAQRGTAADVAELRAILERLVSIDQPYEKSLELDFRFHRRILQAADNLLMQNIMEVIYEFVLTQMAQTTPSPADNELGHKLHIAIVDAIENRDPQAAELAMRQHMEVVLQRLTAMVDAIETDPKED</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQB4</accession>
    <name>A0A518IQB4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_12540</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="42" mass="4459" checksum="0CADE94DDCA3907E" modified="2019-10-16" version="1">MFGIGVLEIIIIAAVGLAGIAIPFCIVYAAVRLGNRDSKKRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQC9</accession>
    <name>A0A518IQC9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Leucine Rich repeats (2 copies)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_12800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="296" mass="32130" checksum="C40886361915067E" modified="2019-10-16" version="1">MVRGGGRKAATIPICCRFRREQLAAVSKYPNLMLQPKRSLLRFPLPLPRRLLSQSIAVAFLIVAAGCGSQQAPDAVVGESDLPSANTVADPNEQSLAQQIADVEASQSERIFLNAPVVDSDLTQLAQLESLSDLLLDGGAVTDTGIAAIVTCPNLKHLRLRFSPIGDDGLRQIAQLKDLEILNLPHSACTAAGIGELADLPKLRQLRLGSDRATAEICQAISRLESLRSLHLIDIPVDDENLLRLADLKNLRSLYIDGGRVSDAGWQALFAKRSDLHVHIDQTHHDLDPGKHDPDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQP2</accession>
    <name>A0A518IQP2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative cadmium-transporting ATPase</fullName>
            <ecNumber evidence="8">3.6.3.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">cadA_2</name>
        <name evidence="8" type="ORF">Mal33_13610</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.3.3" evidence="8"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019829">
        <property type="term" value="F:ATPase-coupled cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027256">
        <property type="entry name" value="P-typ_ATPase_IB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="SSF81653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="SSF81665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01525">
        <property type="entry name" value="ATPase-IB_hvy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="186"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="211"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="241"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="429"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="460"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="779"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="149"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV55390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="825" mass="87647" checksum="87AD1E39DE070BC3" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IR22</accession>
    <name>A0A518IR22_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 13">Phosphoenolpyruvate-protein phosphotransferase</fullName>
            <ecNumber evidence="5 13">2.7.3.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12 13">Phosphotransferase system, enzyme I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="primary">ptsI</name>
        <name evidence="20" type="ORF">Mal33_15180</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>L-histidyl-[protein] + phosphoenolpyruvate = N(pros)-phospho-L-histidyl-[protein] + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:23880"/>
            <dbReference type="Rhea" id="RHEA-COMP:9745"/>
            <dbReference type="Rhea" id="RHEA-COMP:9746"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:29979"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:64837"/>
            <dbReference type="EC" id="2.7.3.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 13 16">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 13">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the PEP-utilizing enzyme family.</text>
    </comment>
    <dbReference type="EC" id="2.7.3.9" evidence="5 13"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008965">
        <property type="term" value="F:phosphoenolpyruvate-protein phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009401">
        <property type="term" value="P:phosphoenolpyruvate-dependent sugar phosphotransferase system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.274.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008279">
        <property type="entry name" value="PEP-util_enz_mobile_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000121">
        <property type="entry name" value="PEP_util_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023151">
        <property type="entry name" value="PEP_util_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036637">
        <property type="entry name" value="Phosphohistidine_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024692">
        <property type="entry name" value="PTS_EI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006318">
        <property type="entry name" value="PTS_EI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008731">
        <property type="entry name" value="PTS_EIN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036618">
        <property type="entry name" value="PtsI_HPr-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05524">
        <property type="entry name" value="PEP-utilisers_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00391">
        <property type="entry name" value="PEP-utilizers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02896">
        <property type="entry name" value="PEP-utilizers_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000732">
        <property type="entry name" value="PTS_enzyme_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47831">
        <property type="entry name" value="SSF47831"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52009">
        <property type="entry name" value="SSF52009"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01417">
        <property type="entry name" value="PTS_I_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00742">
        <property type="entry name" value="PEP_ENZYMES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13" id="KW-0418">Kinase</keyword>
    <keyword evidence="13 16" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11 13 16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 13" id="KW-0598">Phosphotransferase system</keyword>
    <keyword evidence="20" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 13" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="13 20" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 13" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PEP-utilisers_N" evidence="19">
        <location>
            <begin position="5"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="PEP-utilizers" evidence="17">
        <location>
            <begin position="154"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="domain" description="PEP-utilizers_C" evidence="18">
        <location>
            <begin position="255"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="region of interest" description="PEP binding" evidence="15">
        <location>
            <begin position="456"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-phosphohistidine intermediate" evidence="14">
        <location>
            <position position="191"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="14">
        <location>
            <position position="504"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="298"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="334"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="433"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="457"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="467"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00016544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00033235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRNR" id="PIRNR000732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR000732-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR000732-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR000732-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF00391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF02896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF05524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="QDV55541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="581" mass="63900" checksum="65622EDC014EE78A" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IR50</accession>
    <name>A0A518IR50_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">General stress protein 69</fullName>
            <ecNumber evidence="2">1.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">yhdN_2</name>
        <name evidence="2" type="ORF">Mal33_15390</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.1.-" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="1">
        <location>
            <begin position="15"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="327" mass="36451" checksum="E7AA371B19A7B4C3" modified="2019-10-16" version="1">MQYRQLGHLGPRVSEIGFGGWALGGQWGAQDDADSIAALNRAIDLGVNFIDTAAGYGDGRSERLIAEVAKQRSEQLFIATKTPPADGPWPPSPYCAWQDRYSANYLRENIEQRLRNLQVERIDLLQLHTWTRAWNDDPQPLLVLRKLREEGKIGMIGISTPEQDQNCVIQLMRDGLVDCVQVIFNLFDQEPAAQLLPVAEETGTGVIVRVALDEGMLAGKFTAEHRFADDDFRQQYFAGDRLPRSVDRVAEIANDMHRFGLQDYSVADLAIKFALSASGVGSVITGIRSAEQAELNAAVSDKPAVPDTLLHLLRRHNWRRGVWYAGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IR87</accession>
    <name>A0A518IR87_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Multidrug resistance protein MdtN</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_15780</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021980124" evidence="2">
        <location>
            <begin position="29"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="84"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="142"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="309" mass="34351" checksum="0C3972E35254CDB3" modified="2019-10-16" version="1" precursor="true">MNILANHKPLAIALLATSIGLLDNLASAQSDNSPIPVRDSLVEAIDDIKISAGADGILFLDNQDVEEGKLVQAGKVIAMIDPEQAKLNLVLKEAEEQQARLQAENDVNIRAAEKSMEYEWAEAKSAEELHKKQAMPYWDMRREVLEAERSKLAIEMAKNEQQVAVATFAAKTAERRLAEHEIKRRQITATFDGIIARRYAKSGEWVQAGTPIVRVVRIDEIKVEGDVKGLDAPERIVMGAPVAIRVHVGGNRYVDFESRLEYVSPILESDNTYRVWAKIVNRVEGGRYLVSPGMQAEMQIMPPSNVSLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRB4</accession>
    <name>A0A518IRB4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5 6">50S ribosomal protein L20</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">rplT</name>
        <name evidence="7" type="ORF">Mal33_16240</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6">Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the bacterial ribosomal protein bL20 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07026">
        <property type="entry name" value="Ribosomal_L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1900.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00382">
        <property type="entry name" value="Ribosomal_L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005813">
        <property type="entry name" value="Ribosomal_L20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035566">
        <property type="entry name" value="Ribosomal_protein_L20_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10986">
        <property type="entry name" value="PTHR10986"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00453">
        <property type="entry name" value="Ribosomal_L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00062">
        <property type="entry name" value="RIBOSOMALL20"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74731">
        <property type="entry name" value="SSF74731"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01032">
        <property type="entry name" value="rplT_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 6" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV55646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="117" mass="13563" checksum="538331EB3F9C46AC" modified="2019-10-16" version="1">MRTTKGAARTQAKKRLFKRAKGFVGGRGTLLRSVKETLLRSGAYAYRDRRVKKRDFRRLWITRISAACQQREMRYSQFMYGLKKADIQLDRKQLSELAIHDPQAFDVIVEQAKAAIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRM3</accession>
    <name>A0A518IRM3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">IcmF-related_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_17210</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="36"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="76"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="554"/>
            <end position="574"/>
        </location>
    </feature>
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        <location>
            <begin position="327"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="253"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV55742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="580" mass="63006" checksum="33744EC3A5A77499" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
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    <name>A0A518IRW2_9BACT</name>
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        <submittedName>
            <fullName evidence="2">Shikimate 5-dehydrogenase</fullName>
        </submittedName>
    </protein>
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    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetia</taxon>
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    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="Aminiacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013708">
        <property type="entry name" value="Shikimate_DH-bd_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08501">
        <property type="entry name" value="Shikimate_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="SSF53223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Shikimate_dh_N" evidence="1">
        <location>
            <begin position="13"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="275" mass="29098" checksum="93603A23CDE62D76" modified="2019-10-16" version="1">MVVHPAIQPTLCVIGFPVAGNAMQFALERVLVEAGLDWKFVSFNVSPDSFDEAVRGVKALGLAGLAIASPFETQLSTHVERFTTGCDGDGWIDFLQPVQGVWVGSNQLARAVMQLARQAVPEPSQIYILGDGPQARGIAAYFSAHSLSCQYSTAGLQEPAVAVAEGAGAIGESISDVDPLSMENIDPSVIVIRADAEDGKPCSLDSAEIEGCQTAGCCVELALDPATQLPIAEHVVAVSAVDVLVQRFANGFQDWTGLSAEKSTLREAVEEYYEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRZ8</accession>
    <name>A0A518IRZ8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="3" type="ORF">Mal33_18020</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="30"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="68"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="122" mass="13273" checksum="293612A6DCF0A843" modified="2019-10-16" version="1">MNSSERSADSPGTPIEYDTSYLNSLRELKFVGAIGTLALAWTLIYGGLKGYSSDPDAMDVILGMPSWVFWGIAVPWCVTSLATLFFALFILREDDDDLLEQEAQAQAEAEAQAEAASKEDVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IS11</accession>
    <name>A0A518IS11_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name type="scientific">Rosistilla oblonga</name>
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        <lineage>
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    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="62" mass="7010" checksum="EDEE032D326D3729" modified="2019-10-16" version="1">MSSKEKAISLIQNLDDDVSIDDVIDRLYLLRKIELGIVQADTGDVMEHDAFMDELEAEDAQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IS53</accession>
    <name>A0A518IS53_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_19070</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022055685" evidence="1">
        <location>
            <begin position="21"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="217" mass="24533" checksum="96A204C1B736BF53" modified="2019-10-16" version="1" precursor="true">MRPRFTQLIGCVLLASTILAQLGCTSALTTIMYAVGADLQPAEYKDLARQRTAVVVITDGSQYSDDITSRTLTRKVSEFLEIEVDGIKLIPEEEIDSWKDINGWEDLDFVALGKGVKADKVLGIELTGLKLREGQTLYRGRANVTTTVYDVKEGRKEFRRSLDDFTFPVHTGKYASETTEAKFRRDFLEVLSRRVARYFHRYDPRDSVALDAVIVNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISA2</accession>
    <name>A0A518ISA2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Toluene efflux pump periplasmic linker protein TtgG</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ttgG</name>
        <name evidence="5" type="ORF">Mal33_19570</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="17"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="domain" description="HlyD_D23" evidence="4">
        <location>
            <begin position="85"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="147"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV55978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="404" mass="42587" checksum="A2C266DE94895B53" modified="2019-10-16" version="1">MNQTVAPGSRLRWLRTAIGSILVVLAVVGILAAIGYAKVWQIKSAMAAPPPPEMPISVTLAAAEESSFRRSSVVVGNVLAPESITLKTELAGTVTEIPMIPGGEVQRGEVLLRLDIRTEEAMLKSLEASRKLAESTVQRSRQLNRINAGSESELDIAEAELSRAEAGIEELRVRIDKKTLRAPFDARVGLFDLHVGQYLVEGNQVTTLEGIADYFFIDFSMPSHVADAIEIGDDVFLQIGADKLQATATIVAVDASANPISRSVTARARLSNPPPKLQPNDSVHVTVMYGQPIPVRQIPATAVRRGPSGSVVFVATETESGLRAQSRNVVVVPGGSAVARVIDGILAGESIVADGSFKVYEGALLADARSTAASNDESAASVQDAGVPAAVAADVAIQNREAGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISW9</accession>
    <name>A0A518ISW9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_21480</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="137" mass="14205" checksum="3036EAEFABAD0EBF" modified="2019-10-16" version="1">MKRFHSVGLRVAMALMVLGTLGCGPKSGVERLDLSGTVTFEGAPVPVGMVSFEPIDKGVGGGFAPIRNGLFDTADGGRGALSGPTSVRITGFDGIKDPSNPDAPPKALFEAYETTLDLADDQDEIEFALPLEGAQPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISY4</accession>
    <name>A0A518ISY4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Alkaline phosphatase</fullName>
            <ecNumber evidence="7">3.1.3.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">phoA_1</name>
        <name evidence="7" type="ORF">Mal33_21530</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the alkaline phosphatase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.1" evidence="7"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004035">
        <property type="term" value="F:alkaline phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd16012">
        <property type="entry name" value="ALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001952">
        <property type="entry name" value="Alkaline_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018299">
        <property type="entry name" value="Alkaline_phosphatase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11596">
        <property type="entry name" value="PTHR11596"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00245">
        <property type="entry name" value="Alk_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00098">
        <property type="entry name" value="alkPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00123">
        <property type="entry name" value="ALKALINE_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022118036" evidence="6">
        <location>
            <begin position="24"/>
            <end position="536"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV56173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="536" mass="58860" checksum="B59CCA2D55475F86" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IT20</accession>
    <name>A0A518IT20_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_22170</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="202" mass="22922" checksum="9CB00E860ACEA206" modified="2019-10-16" version="1">MTPMEAYEYAASWGSFMRSGDPGACMYGFDSDCRPQSEEHRQDVINHMNRCRLMVTERPEDFDADELEKLEAFVEFITKRNIEGQTDGSFIIEISVCGSVTCCTEDGNDLEAETLSDMKDCNRSGDAEPACQYILDNYKPEFRIVRRVSDVYQNVVASKEEKLQVCRELYGGCDTNFSEEDNANLYLVWAAASNLEAMQEAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IT39</accession>
    <name>A0A518IT39_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Plasmid pRiA4b ORF-3-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_22440</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
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                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
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                <person name="Kallscheuer N."/>
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                <person name="Galperin M.Y."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 4">Mal33</strain>
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    </evidence>
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    </evidence>
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    <sequence length="318" mass="35424" checksum="8B99027E1E71DB35" modified="2019-10-16" version="1" precursor="true">MLRTLLLLLLALVPLSAGAAEKLKALIVDGQNNHGDWPKTTVMMKRYLEETGRFTVDVQRTQYTWNGGKLLDEYPLNDGRKYQSLSKPKSDPDFKPTFSDYDVVINNFGHSAAAWPKETQTALDKFVHSGGGLVVVHAADNAFSEWPQYNKMIGLGGWGGRNEKSGPYVFIDAEGKTVRDTSPGRGGAHGPQHEYQIVVRNPDHPITRGLPRSWMHTKDELYQQLRGPADKMTILATAFAAENFKGTGRHEPIMMTIDYGKGRVYHTPMGHADYSMECVGFITTLIRGTEWAATGDVTLTEVPKDFPTFETASKRSFE</sequence>
</entry>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="1 2">Mal33</strain>
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            <dbReference type="EMBL" id="QDV56570.1"/>
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        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
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</entry>
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
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                <person name="Jeske O."/>
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                <person name="Storesund J.E."/>
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                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
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                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
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                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5 6">Mal33</strain>
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        <property type="entry name" value="CheY-like_superfamily"/>
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        <property type="entry name" value="HATPase_C"/>
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        <property type="entry name" value="HATPase_C_sf"/>
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        <property type="entry name" value="His_kinase_dom"/>
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        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
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    <sequence length="546" mass="60850" checksum="58FB9FBAAB38EDB3" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUD9</accession>
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    <reference evidence="3 4" key="1">
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                <person name="Merkel B.J."/>
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                <person name="Devos D.P."/>
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                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 4">Mal33</strain>
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    </dbReference>
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        <location>
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    </feature>
    <feature type="chain" id="PRO_5022130538" evidence="2">
        <location>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="354"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="811" mass="89516" checksum="E85EA13F588056CC" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUF1</accession>
    <name>A0A518IUF1_9BACT</name>
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        <submittedName>
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    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013022">
        <property type="entry name" value="Xyl_isomerase-like_TIM-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01261">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="SSF51658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AP_endonuc_2" evidence="1">
        <location>
            <begin position="2"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="238" mass="26159" checksum="7421BBFE8CD6EE0F" modified="2019-10-16" version="1">MAAKMGAGAVEIDARTELRPAELTDTGVRQFRKMLDDLNLRISSIRFQTRRGYDVVDDLDRRVEATKQTLRMAFRLGTDVVVNQIGQVPSDPESAAWDHLRCVLDDINRYGAHIGAFLTPETGTEDGADLLRLLDANEESFTPVAFNPGNLIINRFSAGEALRVLGDRVRLICARDGVQDLAAGRGIEVPLGQGLADFHDILGYMENYHYQGWVVVQRSGAADPIAEIADAVGYLANM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUH4</accession>
    <name>A0A518IUH4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acetyl-coenzyme A synthetase</fullName>
            <ecNumber evidence="4">6.2.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">acs</name>
        <name evidence="4" type="ORF">Mal33_27370</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
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    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003987">
        <property type="term" value="F:acetate-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032387">
        <property type="entry name" value="ACAS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
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        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="36"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding" evidence="1">
        <location>
            <begin position="98"/>
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        </location>
    </feature>
    <feature type="domain" description="AMP-binding_C" evidence="2">
        <location>
            <begin position="519"/>
            <end position="598"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV56739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="616" mass="66793" checksum="C57F8283C919CF1A" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUP1</accession>
    <name>A0A518IUP1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cytochrome_C554 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_28120</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023155">
        <property type="entry name" value="Cyt_c-552/4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036280">
        <property type="entry name" value="Multihaem_cyt_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13435">
        <property type="entry name" value="Cytochrome_C554"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48695">
        <property type="entry name" value="SSF48695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome_C554" evidence="1">
        <location>
            <begin position="144"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="337" mass="37287" checksum="0D1A5A9B651BA306" modified="2019-10-16" version="1">MIDQHFAGDAACASCHPKQAAAQRRSGHSRTAVAMSDSDFATELLAGQPYPDSRRPQTFEFTSHSNRFMVRDVDDPGLPALPATWLLGSGTHAQTPIFVDQQAQRGVEMRWSFLANRDGIGLTPEHEKFDQYEAKSLQCYGRPMDAGDVRSCLGCHTTVGPPAQLPIQNDLYVANVGCERCHGPRKQHALLAHQGRGEESKPLVQYASAEAYIDACAQCHRDESSVSPTAQPHELVRFQPYGLKRSRCYLESPDKLTCSTCHDPHDTVSHDRTVYIQQCQQCHQSGHDSLCTANPQGDCIDCHMPATEWTAGIAFHDHEIRIHEALAPKHSTPQVKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUZ7</accession>
    <name>A0A518IUZ7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">FtsX-like permease family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Mal33_29080</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="25"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="573"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="626"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="672"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="723"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="751"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="803"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="1062"/>
            <end position="1083"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="1111"/>
            <end position="1134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="1146"/>
            <end position="1168"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="8">
        <location>
            <begin position="603"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="436"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV56907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1180" mass="127469" checksum="B59FDB705A0487C1" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IV04</accession>
    <name>A0A518IV04_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative N-acetyltransferase YjaB</fullName>
            <ecNumber evidence="2">2.3.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">yjaB</name>
        <name evidence="2" type="ORF">Mal33_29140</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.3.1.-" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13508">
        <property type="entry name" value="Acetyltransf_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="146" mass="16506" checksum="4FC97243F79237CD" modified="2019-10-16" version="1">MNVREALETERDLLVDIWLRSVRATHDFLSEADIERILPLVRDHALVDLEIWVLADAADEPIGFMGLADDKLEALFLAPEHRRRGGGRRMVDHARDLNGRLRVDVNEQNPAALAFYQSLGFVVEGRSELDSAGMPFPILHLRDPAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IV06</accession>
    <name>A0A518IV06_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">pknB_13</name>
        <name evidence="7" type="ORF">Mal33_29200</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="74"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="579"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="646"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="415"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="487"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="646"/>
            <end position="670"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV56919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="687" mass="78697" checksum="6EB1A937953B1482" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IV89</accession>
    <name>A0A518IV89_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_30030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022094668" evidence="1">
        <location>
            <begin position="23"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="146" mass="16078" checksum="319E9E868990DD15" modified="2019-10-16" version="1" precursor="true">MKRYMIQNILTLSTTVAIVLHALLGCCVHHEHACASQEISAVSQSMDHCHGHHHDAGNRCNDGQSDQQSQDAPHPPCDEIDCSLISVVRNLDVSLLFSVTTWVPAIDYAAARSAQASLTSRYGSNDPPDLFFGNQPLRTLTQVWRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVD3</accession>
    <name>A0A518IVD3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aerobic cobaltochelatase subunit CobN</fullName>
            <ecNumber evidence="3">6.6.1.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">cobN</name>
        <name evidence="3" type="ORF">Mal33_30510</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="6.6.1.2" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051116">
        <property type="term" value="F:cobaltochelatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10150">
        <property type="entry name" value="CobN_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003672">
        <property type="entry name" value="CobN/Mg_chltase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44119">
        <property type="entry name" value="PTHR44119"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02514">
        <property type="entry name" value="CobN-Mg_chel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1389"/>
            <end position="1408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1336"/>
            <end position="1383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1340"/>
            <end position="1365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1415" mass="156019" checksum="EB92F6594AD5FFD0" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVK1</accession>
    <name>A0A518IVK1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF4105 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_31170</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025178">
        <property type="entry name" value="DUF4105"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13387">
        <property type="entry name" value="DUF4105"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4105" evidence="1">
        <location>
            <begin position="104"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="303" mass="34393" checksum="8454489CFB0BADBB" modified="2019-10-16" version="1">MRQRLNATNLLLLQTLCLIGGASGCGVLRGDVPATEIAESLPTPAKLVIDLASMEGPSQRRDWRPELSVLPYAEFDDEDDSVIVHNVRQCRWRSSDDYDVKHNDWKFRWEDVQGVDFIVVPFQDTPMLAHTMLSFDLGDDRHMALSIEARLEAGETYSPIAGVARQFDLMYILGDETDLLGLRADVRRNDIFLYRSKATPQQSAQILRSVLERCNQLVQTPEFYDSLRNSCATNVADHIAPFAPASLATDWRLMLPGHSDKLAYDLKLIDNSKPFEQVRREAFVSLKARQHLGSKDFSRLIRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVP3</accession>
    <name>A0A518IVP3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">3-oxoacyl-[acyl-carrier-protein] synthase 3</fullName>
            <ecNumber evidence="7">2.3.1.180</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">3-oxoacyl-[acyl-carrier-protein] synthase III</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Beta-ketoacyl-ACP synthase III</fullName>
            <shortName evidence="7">KAS III</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">fabH_3</name>
        <name evidence="7" type="synonym">fabH</name>
        <name evidence="11" type="ORF">Mal33_31550</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>acetyl-CoA + H(+) + malonyl-[ACP] = 3-oxobutanoyl-[ACP] + CO2 + CoA</text>
            <dbReference type="Rhea" id="RHEA:12080"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9625"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="ChEBI" id="CHEBI:78450"/>
            <dbReference type="EC" id="2.3.1.180"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="7">The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the thiolase-like superfamily. FabH family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.180" evidence="7"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033818">
        <property type="term" value="F:beta-ketoacyl-acyl-carrier-protein synthase III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01815">
        <property type="entry name" value="FabH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013751">
        <property type="entry name" value="ACP_syn_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013747">
        <property type="entry name" value="ACP_syn_III_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004655">
        <property type="entry name" value="FabH_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08545">
        <property type="entry name" value="ACP_syn_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08541">
        <property type="entry name" value="ACP_syn_III_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00747">
        <property type="entry name" value="fabH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="4 7" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2 7" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="5 7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ACP_syn_III" evidence="10">
        <location>
            <begin position="199"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="ACP_syn_III_C" evidence="9">
        <location>
            <begin position="330"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="67"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="ACP-binding" evidence="7">
        <location>
            <begin position="347"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="205"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="346"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QDV57154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="419" mass="44292" checksum="43806BA71291411E" modified="2019-10-16" version="1">MYVGADIEHKSAGSRSGLSPSRMSVCRKSSNSCIMGTVQASKPHWNCCLFCSRLLSASYRMSQITESSSAGTRSASNRGSAPLTQTGGRSRLGQALGVRVASTGSYAPAEIVTNDDLASLGCDSEWIIKRTGIRERRKARPDEATSDMAYEAASRCLKDAGVDASEVDMILVATMTPDHPTPSAACHLQRRLGATAPAMDVNAACAGFMYAMVTGSQFVAAGNAKKVLVVGADLMSRTINPHDPKTYPLFGDGAGAVLLVPDKPEGAGLLKYTLGSEGCGGKMLCIPAGGSRTPLVPDAFNEGRHYLWMDGRAVFKWAVRVVAESSIDVLNELGMGPDDLNLIILHQANQRIIDSAVSDLGVHRESVFVNVDRYGNTSAASIPLALDEAVRAGKIERGQHALLCGFGAGLAWGTAVLRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVR8</accession>
    <name>A0A518IVR8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_31810</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="513" mass="57061" checksum="E9F51AAE98799369" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVY3</accession>
    <name>A0A518IVY3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">WGR domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_32520</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025406">
        <property type="entry name" value="DUF4132"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043782">
        <property type="entry name" value="DUF5724"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036930">
        <property type="entry name" value="WGR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008893">
        <property type="entry name" value="WGR_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13569">
        <property type="entry name" value="DUF4132"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18991">
        <property type="entry name" value="DUF5724"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05406">
        <property type="entry name" value="WGR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00773">
        <property type="entry name" value="WGR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142921">
        <property type="entry name" value="SSF142921"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WGR" evidence="2">
        <location>
            <begin position="1797"/>
            <end position="1864"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="600"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1166"/>
            <end position="1193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1166"/>
            <end position="1187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1864" mass="208470" checksum="8F871BC8B4C316BB" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IW15</accession>
    <name>A0A518IW15_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 7" type="primary">rplB</name>
        <name evidence="7" type="ORF">Mal33_32880</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01320_B">
        <property type="entry name" value="Ribosomal_L2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022666">
        <property type="entry name" value="Rbsml_prot_L2_RNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_L2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002171">
        <property type="entry name" value="Ribosomal_L2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005880">
        <property type="entry name" value="Ribosomal_L2_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022669">
        <property type="entry name" value="Ribosomal_L2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022671">
        <property type="entry name" value="Ribosomal_L2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014726">
        <property type="entry name" value="Ribosomal_L2_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13691">
        <property type="entry name" value="PTHR13691"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00181">
        <property type="entry name" value="Ribosomal_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03947">
        <property type="entry name" value="Ribosomal_L2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002158">
        <property type="entry name" value="Ribosomal_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01383">
        <property type="entry name" value="Ribosomal_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01382">
        <property type="entry name" value="Ribosomal_L2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01171">
        <property type="entry name" value="rplB_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00467">
        <property type="entry name" value="RIBOSOMAL_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L2_C" evidence="6">
        <location>
            <begin position="125"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="33"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="215"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="266"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV57284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="286" mass="31250" checksum="CBCB18E63359D4B6" modified="2019-10-16" version="1">MGIRVYKPTSAGRRNASVSDFKELTKGAVPEKRLLRPKRKTAGRNNQGKITARHRGGGHKQMYRIIDFRRVKDNIPATVDSIQYDPNRSARIALLKYADGEKHYVIAPDGLTAGDPILNGPDAPPKVGNCLPLKNIPLGTTVCCVELRPGAGASFCRSAGTEATLMAREADWAQLSLPSGEIRRVSSKCRATIGKVSNTDHMKVVLGKAGRARWLGRRPHVRGTAMNPIDHPHGGGEGRTKGGRHPVSPQGKNAKGGATRQRRKPSNSSIVRRRRSRRYGQLKLIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IW29</accession>
    <name>A0A518IW29_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">50S ribosomal protein L14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3 6" type="primary">rplN</name>
        <name evidence="6" type="ORF">Mal33_32810</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 5">Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the universal ribosomal protein uL14 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.150.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01367">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036853">
        <property type="entry name" value="Ribosomal_L14_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000218">
        <property type="entry name" value="Ribosomal_L14P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005745">
        <property type="entry name" value="Ribosomal_L14P_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019972">
        <property type="entry name" value="Ribosomal_L14P_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11761">
        <property type="entry name" value="PTHR11761"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00238">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01374">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50193">
        <property type="entry name" value="SSF50193"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01067">
        <property type="entry name" value="rplN_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00049">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 5" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV57277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="122" mass="13306" checksum="E845DD63E48E6932" modified="2019-10-16" version="1">MIQQETRLTVADNTGAREVMCIKVLGGSRRRTAGLGDVIVCSVKSTIPGSDVKKKAVVKAVIVRTKSPTRRNDGSYIRFDSNAVVIVDNDKNPRGTRIFGAVARELREKSFMKIVSLASEVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IW67</accession>
    <name>A0A518IW67_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_33210</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="158" mass="17256" checksum="8C8084BF717DC352" modified="2019-10-16" version="1">MFTEKAATHPPRDRTSNDNPAARRVRFVVAVAAIGLLNLSFAAMVAFNGDASATKASLLFLGHLALQAILIIQLAKLLYRQHGVRQLRFGVSALMILTAICALPMGVVRIAMTGGSAARADWAFYYGLTLVFALFPLLVVCEAGWVWRAAVRKRRQSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IW78</accession>
    <name>A0A518IW78_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Dna-J like membrane chaperone protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_33530</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3680.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029024">
        <property type="entry name" value="TerB-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158682">
        <property type="entry name" value="SSF158682"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="118" mass="13001" checksum="D1D5B18C6312B6EA" modified="2019-10-16" version="1">MDRIAYLKNLVVMAIADGALAEHELSLLSQRCAELGFEEQELCDAVSYALGDDAQLELPTDPADQEAVLSDLIRMMAADGQMSESEKRLFALAAARMDFSGEKLERLIDRVVRTNHSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWQ0</accession>
    <name>A0A518IWQ0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Soluble aldose sugar dehydrogenase YliI</fullName>
            <ecNumber evidence="6">1.1.5.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">yliI_1</name>
        <name evidence="6" type="ORF">Mal33_35060</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.5.-" evidence="6"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012938">
        <property type="entry name" value="Glc/Sorbosone_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013427">
        <property type="entry name" value="Haem-bd_dom_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036280">
        <property type="entry name" value="Multihaem_cyt_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011041">
        <property type="entry name" value="Quinoprot_gluc/sorb_DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00034">
        <property type="entry name" value="Cytochrom_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07995">
        <property type="entry name" value="GSDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48695">
        <property type="entry name" value="SSF48695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50952">
        <property type="entry name" value="SSF50952"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02603">
        <property type="entry name" value="CxxCH_TIGR02603"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome c" evidence="5">
        <location>
            <begin position="846"/>
            <end position="984"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV57496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="984" mass="107620" checksum="A190834E6224AA1F" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWQ8</accession>
    <name>A0A518IWQ8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Sensor protein ZraS</fullName>
            <ecNumber evidence="6">2.7.13.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">zraS_2</name>
        <name evidence="6" type="ORF">Mal33_35340</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.13.3" evidence="6"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PAS" evidence="4">
        <location>
            <begin position="34"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="5">
        <location>
            <begin position="91"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="3">
        <location>
            <begin position="181"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="134"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV57524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="391" mass="44187" checksum="CA730E210EE10056" modified="2019-10-16" version="1">MKTKPEIKSEARGEISNDYFRAIANYTYDWESWLSPSGRLLWVNAAVHRMTGYWPDECLAMKDYPLPMIAPEDRARISAMMHQAKAGQFGNDVEFRAIHRDGSVRWMAVSWQPMYDEAGKHLGFRASARDFTERQKLRDQLRLHAEHLEQLVQERTARIAQLELHRRKMEKLAALGQLAAGVAHEVNNPLAGIRNAFALIKGDMSPEHEHYELLELIDREIERISSITHQMYQLYRPSAQHKSLLTIEHTIADVVSLLEPVAKQFEVQLEFHPAKRPTEITLPEGEVKQILLNLIRNAIQASPVGETVTIAVESTQLAVRVEVSDRGEGIAPETLSQIFDPFFSTKTGQPRQGMGLGLSVSRSLIEAMGGSIEVDSEVGRGSKFIAVFRKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWR0</accession>
    <name>A0A518IWR0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Quaternary ammonium compound-resistance protein SugE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">sugE_1</name>
        <name evidence="6" type="ORF">Mal33_35410</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000390">
        <property type="entry name" value="Small_drug/metabolite_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045324">
        <property type="entry name" value="Small_multidrug_res"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30561">
        <property type="entry name" value="PTHR30561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00893">
        <property type="entry name" value="Multi_Drug_Res"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="59"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="84"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV57531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="104" mass="10885" checksum="44E8B1B281F33156" modified="2019-10-16" version="1">MAWLYLVIAGLLEVAWAIGLKQTEGWTRLVPSMITVVLMIASFYFLSHAIKEIPLGTGYAIWTGIGAVGTASLGILLFGEPATAVRIACIGLIIGGIVGLKLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWR4</accession>
    <name>A0A518IWR4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histone deacetylase-like amidohydrolase</fullName>
            <ecNumber evidence="3">3.5.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">hdaH</name>
        <name evidence="3" type="ORF">Mal33_35390</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the histone deacetylase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.-" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.800.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000286">
        <property type="entry name" value="His_deacetylse"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023801">
        <property type="entry name" value="His_deacetylse_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037138">
        <property type="entry name" value="His_deacetylse_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00850">
        <property type="entry name" value="Hist_deacetyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01270">
        <property type="entry name" value="HDASUPER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="SSF52768"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hist_deacetyl" evidence="2">
        <location>
            <begin position="19"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="310" mass="33712" checksum="41B14A45D5BDE845" modified="2019-10-16" version="1">MTILYYDPIFMEHLTGDHPERGGRILPAVRNLSFLALDSACKRPAWESVSKDRLFYVHQHKYIEALQQMAETGGGLIDTDTVVSPKSYEVALKATGAVCDAVCRVVAGEDKTAFCLIRPPGHHAMPDHGMGFCLFNNIAVGARVATNELGIERVLIVDFDVHHGNGTQAMFWEAADVGYYSMHRSPLYPHTGAADEIGAGPGKGTTMNLPVALGTPREEQLETFTASVHAFADKIKPQLVMVSAGFDAHKEDPIGSLGLESEDFRTLTRVLLDVANKHSDGRLVSVLEGGYNAEAMAECVPIHLEQLLEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IX40</accession>
    <name>A0A518IX40_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Replication-associated recombination protein A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rarA</name>
        <name evidence="4" type="ORF">Mal33_36660</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009378">
        <property type="term" value="F:four-way junction helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032423">
        <property type="entry name" value="AAA_assoc_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008921">
        <property type="entry name" value="DNA_pol3_clamp-load_cplx_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021886">
        <property type="entry name" value="MgsA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008824">
        <property type="entry name" value="RuvB-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16193">
        <property type="entry name" value="AAA_assoc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12002">
        <property type="entry name" value="MgsA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05496">
        <property type="entry name" value="RuvB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48019">
        <property type="entry name" value="SSF48019"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="3">
        <location>
            <begin position="51"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV57653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="438" mass="47871" checksum="A42CC3D35F2F89D2" modified="2019-10-16" version="1">MSLFDEAEADHLEANKPLAARMRPRQLTEFAGQEQLLGEGKLLRRMIDARQLGSILFFGPPGTGKTTLAELLAYETGGRFHSLSAVLSGVKELREVLAQARDDVSAGAPRPILFIDEIHRFNKSQQDALLPDVEAGIVTLVGATTSNPYFAINAALISRSQVFQFEPLSNAEIVDLLQRAIRTPQRGLGDIPIEADDEALQYIATMVEGDARKALGALEIGVLSSSDRPVRFDLKLASESLQQKSIRYDGTGDEHYDMASALIKSLRGSDPDASLYWLARMLEGGEDVRFLCRRLVILASEDIGNADPQALPLAVAAMQACEFIGLPECQLTLSQTVIYLALAPKSNSATTAIGNARTEVRQGDLVPVPVALRDKHYQGAKDLGHGEGYLYAHNHADGVAAMDYLGIDREFYEPSGRGFEQELAERLVKIREKLKQAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXB9</accession>
    <name>A0A518IXB9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Exodeoxyribonuclease 7 large subunit</fullName>
            <ecNumber evidence="5">3.1.11.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Exodeoxyribonuclease VII large subunit</fullName>
            <shortName evidence="5">Exonuclease VII large subunit</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 10" type="primary">xseA</name>
        <name evidence="10" type="ORF">Mal33_37400</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield nucleoside 5'-phosphates.</text>
            <dbReference type="EC" id="3.1.11.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5">Heterooligomer composed of large and small subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5 6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the XseA family.</text>
    </comment>
    <dbReference type="EC" id="3.1.11.6" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009318">
        <property type="term" value="C:exodeoxyribonuclease VII complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008855">
        <property type="term" value="F:exodeoxyribonuclease VII activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006308">
        <property type="term" value="P:DNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04489">
        <property type="entry name" value="ExoVII_LU_OBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00378">
        <property type="entry name" value="Exonuc_7_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003753">
        <property type="entry name" value="Exonuc_VII_L"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020579">
        <property type="entry name" value="Exonuc_VII_lsu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025824">
        <property type="entry name" value="OB-fold_nuc-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30008">
        <property type="entry name" value="PTHR30008"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02601">
        <property type="entry name" value="Exonuc_VII_L"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13742">
        <property type="entry name" value="tRNA_anti_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00237">
        <property type="entry name" value="xseA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5 6" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="3 5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5 6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA_anti_2" evidence="9">
        <location>
            <begin position="38"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="Exonuc_VII_L" evidence="8">
        <location>
            <begin position="154"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="domain" description="Exonuc_VII_L" evidence="8">
        <location>
            <begin position="361"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="13"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV57727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="437" mass="48169" checksum="9CD3070C44A7CFCB" modified="2019-10-16" version="1">MKAGRKFGKSQAKQQFPRLSEPLSTSNSSTPTAKPTALSVTQLNNQVKQTLEGQFRNIWVAGEITDIARPHSGHVYLTLKDQKSQVRGVIWRSAAERLRFDLQDGQSVLCQGDVDVYGARGTYQLVIRRVELRGVGDLQHALRQLQQKLQAEGLFDPARKRPLPRFPRRIGLVTSPTSAAVHDFLEVAQRRWPDLNVLIIPTKVQGAEAAGEIVAGIDAAHRIDPPLDVLVVARGGGSVEDLWCFNDERVVRAIAASKIPLVSAIGHEIDVTLSDLASDRRALTPSEAGELVVRSRADLSAELTKLADDLRVRIFQKHANQQAQLEQLSRRPAFTRPFDRITQQALWFDEAEMRFNRGIQQVVTKMRQQLASAAELLDAVGPLKVLARGYSVTQTADSGKLVQSIDQLEVGQSIQTVLADGKVRSTVDAIVGSDDRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXE9</accession>
    <name>A0A518IXE9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_37700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="66" mass="7252" checksum="CB152EA515B4AE7A" modified="2019-10-16" version="1">MGTRLNDVRLQGTACTKLSTSSATQSFPIDQLVAKADLRAAAPRSFEPFDRCRFAGLWIDVDHRAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXL0</accession>
    <name>A0A518IXL0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">AAA_27 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_38360</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038734">
        <property type="entry name" value="YhaN_AAA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13514">
        <property type="entry name" value="AAA_27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="493"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="523"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="domain" description="AAA_27" evidence="4">
        <location>
            <begin position="1"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="735"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1241"/>
            <end position="1287"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="190"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="282"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="336"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="457"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="556"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="619"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="671"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="885"/>
            <end position="933"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="735"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1254"/>
            <end position="1268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV57821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1287" mass="147443" checksum="42EEFFA2D24388ED" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXN2</accession>
    <name>A0A518IXN2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Addiction module component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_38520</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013406">
        <property type="entry name" value="CHP02574_addiction_mod"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09720">
        <property type="entry name" value="Unstab_antitox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02574">
        <property type="entry name" value="stabl_TIGR02574"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="76" mass="8809" checksum="424CB92DF80D482B" modified="2019-10-16" version="1">MTIDLAELRSLPVSEKLRIVEALWDDISASEESIVLQPWKRDEAHRRSQEMKADPSMAVDRDELWRRVDGSCGRNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXT1</accession>
    <name>A0A518IXT1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_39160</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="195" mass="20804" checksum="F34A9F23025C62B7" modified="2019-10-16" version="1">MLELLLVLVLIAALSAMAVPAISVLMADGRIKRAGDEIRIVLAQSRLKAMRTGRTHMFRCEIGTSRYSVQPWNDASDMTEAADMSGQTLPGTAGTQAAVASYTPPEPTAADILELPENIVFADEQVESSQRSMFILQQAAMAAEAGWSQPILLYADGTTSTAVLRVKSEDGSVVKVQLRGLTGEAMVSEVTSDES</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXU8</accession>
    <name>A0A518IXU8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GDSL-like Lipase/Acylhydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_39290</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021820258" evidence="1">
        <location>
            <begin position="25"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="domain" description="SGNH_hydro" evidence="2">
        <location>
            <begin position="63"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="241" mass="26331" checksum="7C2515188E231BB8" modified="2019-10-16" version="1" precursor="true">MTLRRMTSVSCFLIAAMLTSVASAQATATKHDAITPVPRSGNWVKRHESMNARVAKGNVDLVFIGDSITQGWEGRGKKVWADFYGDRNAVNLGIGGDRTQHVMWRLDNGNLEGISPKLAVVMIGTNNSGRNKPEEIAEGVTAIIHQLREKTPETKILLLATFPRGATPADPKRQANETSNAIVAKLADNENIFYLDIGDKFLADDGSLSKEIMPDLLHLSEQGYTIWAESIEPSVSKLMGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IY43</accession>
    <name>A0A518IY43_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative enoyl-CoA hydratase echA8</fullName>
            <ecNumber evidence="2">4.2.1.17</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">echA8_2</name>
        <name evidence="2" type="ORF">Mal33_40240</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.17" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004300">
        <property type="term" value="F:enoyl-CoA hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.12.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014748">
        <property type="entry name" value="Enoyl-CoA_hydra_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="256" mass="27444" checksum="7A7A437D034A30F0" modified="2019-10-16" version="1">MEEWILVDSIQPGIESIVLNRPGRRNALSIELLDQLSAALKRIESDRGNRVVILRAAGPVFSAGLDLREAADHALVERSAAAVERALRQLRETSLIVIAAVQGGAFAGGAGLMAACDLVIAAEDAKFGFPEARRGLLPALICDVLRHKVREGDLRELFLLGEPVDAARAQQVGLVQRIVAADQLRVAAVAAAEAVIAGGPQTIRQTKRLINETFAVPKTNDAGDSIKKHLAARHSAEAHEGLAAFIEKRDPRWEAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IY67</accession>
    <name>A0A518IY67_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_40520</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="198" mass="21707" checksum="0110EC3A13D36027" modified="2019-10-16" version="1">MITVWLLAFPKSFLNVGLSSKTVRNGAIANCKMNMATWLLQSPIGMQFRTSKRTAVQAKDGGACAGYYHAKGVAAISRWLSGSDATGRVRQAISRPRKGRSTLVGMPLPRLRQSHRPHAEHKIACPQIGAPPKKGNACVTSKFGCPENPLFRSTISHESFGRACPHHHVVMLNVPKIIEDSPEYVKIEIGSRVFYSDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IY82</accession>
    <name>A0A518IY82_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MazG nucleotide pyrophosphohydrolase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_40640</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11531">
        <property type="entry name" value="NTP-PPase_BsYpjD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012359">
        <property type="entry name" value="MazG-related_YpjD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004518">
        <property type="entry name" value="MazG_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42692:SF1">
        <property type="entry name" value="PTHR42692:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03819">
        <property type="entry name" value="MazG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029904">
        <property type="entry name" value="UCP029904_pph"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MazG" evidence="1">
        <location>
            <begin position="25"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="115" mass="12833" checksum="32B4F194F60A7748" modified="2019-10-16" version="1">MAEITIADAQKLVDDWIQTLGVRYFSELTNLAQLTEEVGELARILSRQFGDQVAKPGESPGDAGDELADILFVTICLANQMGIDLSDAFERNLVKKTVRDKDRHVNNPKLCDDQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IY97</accession>
    <name>A0A518IY97_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Inositol 2-dehydrogenase</fullName>
            <ecNumber evidence="3">1.1.1.18</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">iolG_13</name>
        <name evidence="3" type="ORF">Mal33_40780</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.1.18" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050112">
        <property type="term" value="F:inositol 2-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004104">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02894">
        <property type="entry name" value="GFO_IDH_MocA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GFO_IDH_MocA" evidence="1">
        <location>
            <begin position="36"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="domain" description="GFO_IDH_MocA_C" evidence="2">
        <location>
            <begin position="169"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="374" mass="41025" checksum="B00634BD0C87481B" modified="2019-10-16" version="1">MSSNDDYGLSKPKAVVAIDPPAIDYRPPTPRNCDRKIALIGAGGISQSHLAAYRRAGFNVAAIVDRTLSKAEAMRDQYFPNAETLTDYRALLTRDDLEVFDVTPHPADRLPILEDAIAAGKHVLSQKPLVLDLDDGQRLASLAAQHRVQLAVNQNGRWAPHFRYMLQAVRSGLIGDVVSIDFALQWDQTWIAGIEALEQIDHLILFDFGIHWFDITTCLMAGQTPRNVWALATKQREQKYRPAALATAVVEYPGAQVRIAFNGHVTRGESDVTTIVGTHGTLRSQGPGLNDQPRIDGFLPDGTFHAALEGCWFEQGFQGAMAELLCAIEDDRAPEHNATQNLESLALCFAAVESANSGRVVPVGSVRRIENQRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYE8</accession>
    <name>A0A518IYE8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_41320</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="57" mass="6630" checksum="8BFEE05D4FB6709B" modified="2019-10-16" version="1">MNESSLVADAAEHDDDLGGDNRQFWAEQLRCAEPTDRVQKIWAICFRRGFDFEKPML</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYL2</accession>
    <name>A0A518IYL2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative symporter YidK</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">yidK</name>
        <name evidence="8" type="ORF">Mal33_41750</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1730.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038377">
        <property type="entry name" value="Na/Glc_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001734">
        <property type="entry name" value="Na/solute_symporter"/>
    </dbReference>
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        </source>
    </evidence>
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        <source>
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    </evidence>
    <sequence length="542" mass="58731" checksum="A9AF14BAEDD99637" modified="2019-10-16" version="1"> </sequence>
</entry>
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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                <person name="Pinto D."/>
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                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
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                <person name="Jeske O."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4 5">Mal33</strain>
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        </location>
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    </feature>
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        <location>
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            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
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    </evidence>
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        </source>
    </evidence>
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            <dbReference type="EMBL" id="QDV58250.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="292" mass="31454" checksum="DED7EB3A1F60DFEA" modified="2019-10-16" version="1" precursor="true">MTSIIPTPLTGTPLPRRLFSTLALGLCCLLTSAAPSLGEDPASDKATPAAVVPKDPQQFHLFLLVGQSNMAGRGKVTAEDQKTDPRVLMFDKANQWVPAKDPLHFDKPGIAGVGLGKTFALDYAADHPGVTVGLIPCAVGGSSINVWKPGGFHKQTKSHPWDDCQARTQLALPAGTLKGILWHQGESDAGKSSAPGYQAKLHDLVARFRADLKAPEVPFLVGQLAQFPDRPWSDSKRLVDAAHRSLLESVPFTAFVPSDGLTPKSDNVHFDAASMREFGHRYYKAYQGLQVK</sequence>
</entry>
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        <submittedName>
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            <authorList>
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                <person name="Pinto D."/>
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                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
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                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
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                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
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        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
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</entry>
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    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
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                <person name="Lage O.M."/>
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                <person name="Jetten M.S.M."/>
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                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">Mal33</strain>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="410"/>
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        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13533"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="QDV58298.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="660" mass="71854" checksum="0F9C9363D0EC861F" modified="2019-10-16" version="1"> </sequence>
</entry>
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    <accession>A0A518IZ37</accession>
    <name>A0A518IZ37_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
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    </protein>
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    <organism evidence="1 2">
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        <lineage>
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    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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                <person name="Rivas-Marin E."/>
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                <person name="Peeters S.H."/>
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                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
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                <person name="Storesund J.E."/>
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                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
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                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="203" mass="21321" checksum="91AC76428754FF84" modified="2019-10-16" version="1">MNSVRIACVLMVALSAGCSKEKMTELVDQAKETASSVAADVSTEMKTAAEQTVAKVESVKEAAADVSGIGDATGKATMTLDAPTEFAASYVQLIAVNEGRPSVLKISSSKDGQDDVFPAFLIQAKLSDTDLDSLVGQTVSARLFAQKQEGGPIWFSPEEKPVPVTLAMEEGNWIARIDNASVMNSSSDAETSISGTFQCVVHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZC0</accession>
    <name>A0A518IZC0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative Mg(2+) transport ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Mal33_44610</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MgtC/SapB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003416">
        <property type="entry name" value="MgtC/SapB/SrpB/YhiD_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33778">
        <property type="entry name" value="PTHR33778"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02308">
        <property type="entry name" value="MgtC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01837">
        <property type="entry name" value="MGTCSAPBPROT"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="100"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="124"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV58438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="161" mass="17016" checksum="779F626E8B0600B4" modified="2019-10-16" version="1">MLQELDVQNLQTIAIAAACGAVLGIEREIAGKPAGIRTHIFVSAGSALMMILGQEIVDQFAQHEKDALLKADPIRILQAIVVGISFLGAGTIVHQKREGVEGLTTAATIYLTAGIGVATAVGRVSLALILTAFAAVVLVVLGFVEDRIARHFHRKKAKKLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZF0</accession>
    <name>A0A518IZF0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glutamate-ammonia-ligase adenylyltransferase</fullName>
            <ecNumber evidence="5">2.7.7.42</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">glnE</name>
        <name evidence="5" type="ORF">Mal33_44910</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.7.42" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008882">
        <property type="term" value="F:[glutamate-ammonia-ligase] adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023057">
        <property type="entry name" value="GlnE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005190">
        <property type="entry name" value="GlnE_rpt_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013546">
        <property type="entry name" value="PII_UdlTrfase/GS_AdlTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30621">
        <property type="entry name" value="PTHR30621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08335">
        <property type="entry name" value="GlnD_UR_UTase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03710">
        <property type="entry name" value="GlnE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GlnE" evidence="3">
        <location>
            <begin position="98"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="domain" description="GlnD_UR_UTase" evidence="4">
        <location>
            <begin position="362"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="domain" description="GlnE" evidence="3">
        <location>
            <begin position="624"/>
            <end position="869"/>
        </location>
    </feature>
    <feature type="domain" description="GlnD_UR_UTase" evidence="4">
        <location>
            <begin position="895"/>
            <end position="1027"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV58468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1030" mass="114971" checksum="A35CE58411A4B43F" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZT2</accession>
    <name>A0A518IZT2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_46310</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="142" mass="16210" checksum="F17403D5F42B7C31" modified="2019-10-16" version="1">MADYVIRRVVISTVFLVVILTGLATASSEDNFDGAVWKFQMTNKLNPSSVFVGRFRVSNHILYQKASPSDPKYSKRVGENHPNHKKTRFEVIDFRVFTQIGKKMSTIKGTGRLSYKELGEWSGLFTDGDGNNWKFKAERIQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0H5</accession>
    <name>A0A518J0H5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_48650</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010869">
        <property type="entry name" value="DUF1501"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07394">
        <property type="entry name" value="DUF1501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021824271" evidence="1">
        <location>
            <begin position="46"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="487" mass="53127" checksum="1181F5CE74AC8B24" modified="2019-10-16" version="1" precursor="true">MKSPFQFPCQRQQPQATSRREMLTRTASGFGAVALAALGADPAFAAGSQDAKTLGAPLHGLHHQPRAKNVIFLYMDGGPSQVDTFDPKPLLTKFNGRDPADFFPVEPTQFNNTGKVLGSPWKFDSHGESGIPVSALFPHVAGCVDELAVVRSMVSEFPEHTFANYFLHTGSGLQGRPSMGAWVNYGLGSECQDLPGFVVINGGLIPPGGLDCFGSGFLPASYQGSVFKPSGSAVANIQRTEKSAEAQIRKLALVRGLDNMAVDQFGKHDSLESAIQNYELAYQMQMAVPELMSLADEPDYIQSMYGMDAEYAPTKIYASQCLLARRLVERGVRFIELTCPAVGGDRWDQHNNLKQGHENNARAVDQPIAALLKDLRQRGMLDETLVVWAGEFGRTPFAQGKNGRDHNPQGFTIWMAGGGVKPGTVYGATDEFGYKAIENRLEIHDLHATMLHLLGVDHTRSTFRFGGRDMRLTDVKGHVVKELIQSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0J5</accession>
    <name>A0A518J0J5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Gluconolactonase</fullName>
            <ecNumber evidence="3">3.1.1.17</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">gnl_3</name>
        <name evidence="3" type="ORF">Mal33_48920</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.1.17" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004341">
        <property type="term" value="F:gluconolactonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013658">
        <property type="entry name" value="SGL"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08450">
        <property type="entry name" value="SGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022169823" evidence="1">
        <location>
            <begin position="27"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="domain" description="SGL" evidence="2">
        <location>
            <begin position="45"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="327" mass="35991" checksum="2C1612E965CE726E" modified="2019-10-16" version="1" precursor="true">MLTVHRFHRLLALASLLLIASITDVAAEEAVFLSEPKMLQEHGAGEGPVWHPQLGLLTSGEGNINRRDLSGKTSIYREGAGTNGLLFDRRGRLVVCDNVRRQITRIDPDGTATVLTKSYEGQRYNQPNDLTIDSKNRIYFTDPQYGKRSGMEIRDRDGREIEGVYRIDPDGSVVRIIAHEVDRPNGLIVTPDDKYLFVADNNNSLGGARKLWRFALDGDGMPDLASQTLIHDWKTTRGPDGMKLDQQGRLYVAAGLNKPHLPQETADPPTAGIYVFSAAGKLIDFVAIPRDETTNCGFGGEDGKTLFVTAGGSLWSIQTAVPGYQIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0L8</accession>
    <name>A0A518J0L8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Amylo-alpha-1,6-glucosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_48700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004134">
        <property type="term" value="F:4-alpha-glucanotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004135">
        <property type="term" value="F:amylo-alpha-1,6-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005980">
        <property type="term" value="P:glycogen catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010401">
        <property type="entry name" value="AGL/Gdb1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032790">
        <property type="entry name" value="GDE_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024742">
        <property type="entry name" value="Glycogen_debranch_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10569">
        <property type="entry name" value="PTHR10569"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06202">
        <property type="entry name" value="GDE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12439">
        <property type="entry name" value="GDE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GDE_N" evidence="2">
        <location>
            <begin position="11"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="domain" description="GDE_C" evidence="1">
        <location>
            <begin position="278"/>
            <end position="639"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="645" mass="72111" checksum="82DBC411771FEE8D" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0R4</accession>
    <name>A0A518J0R4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">HTH-type transcriptional repressor ComR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">comR</name>
        <name evidence="3" type="ORF">Mal33_49550</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023772">
        <property type="entry name" value="DNA-bd_HTH_TetR-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01081">
        <property type="entry name" value="HTH_TETR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="6"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="193" mass="21855" checksum="F827AE450D7503B4" modified="2019-10-16" version="1">MPWEKSFDEAEVLDKAMHVFWEKGYASTSITDLTTATGIQRGSLYNAFSGKQELFVRSLLKYDTEQRRTLIQKLERMDDPIKAFAFLFDAIVQQSLDDPKKKGCFLINTSLTLGDHDAAAQKIVGTSLREFTEFFEKQIKLGQQRKQIPKSVDPEPTARTLFALLVGMRVMARGSFDKPALQQVADQAMRLVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0T7</accession>
    <name>A0A518J0T7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Arylsulfatase</fullName>
            <ecNumber evidence="6">3.1.6.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">atsA_33</name>
        <name evidence="6" type="ORF">Mal33_49690</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="PTM">
        <text evidence="3">The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the sulfatase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.6.1" evidence="6"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004065">
        <property type="term" value="F:arylsulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
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        <property type="entry name" value="Sulfatase_CS"/>
    </dbReference>
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        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021849760" evidence="4">
        <location>
            <begin position="23"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase" evidence="5">
        <location>
            <begin position="31"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="modified residue" description="3-oxoalanine (Cys)" evidence="3">
        <location>
            <position position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR600917-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV58944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="605" mass="66718" checksum="B91598A73281C28A" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0X9</accession>
    <name>A0A518J0X9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative isomerase YddE</fullName>
            <ecNumber evidence="2">5.1.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">yddE</name>
        <name evidence="2" type="ORF">Mal33_50190</name>
    </gene>
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        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="5.1.-.-" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003719">
        <property type="entry name" value="Phenazine_PhzF"/>
    </dbReference>
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        <property type="entry name" value="PTHR13774"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02567">
        <property type="entry name" value="PhzC-PhzF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016184">
        <property type="entry name" value="PhzC_PhzF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00654">
        <property type="entry name" value="PhzF_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="1">
        <location>
            <position position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR016184-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="262" mass="28330" checksum="F2853EC0015515AF" modified="2019-10-16" version="1">MSIRIVQIDAFTDRPFAGNPAAVCLLEQPREVDWMQAVAAEMNLSETAFVRPIDVGYELRWFTPQVEVDLCGHATLAAAHALWTEARISPNETLRFQTRSGQLTARRDGALIQLDFPATPAKPCDPPAGLMGALPVDPIFVGETKFDTLVVIESEAQLRSLQPDFARLAKIPTRGVIVTCGSESPEFDFLSRFFGPAAGIDEDPVTGSAHCCLAPYWGQQLGKTEMTGYQASSRGGIVKTQIAGDRILLSGAAVTVLRGELV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0Y8</accession>
    <name>A0A518J0Y8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_50230</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002838">
        <property type="entry name" value="AIM24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036983">
        <property type="entry name" value="AIM24_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016031">
        <property type="entry name" value="Trp_RNA-bd_attenuator-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01987">
        <property type="entry name" value="AIM24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51219">
        <property type="entry name" value="SSF51219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00266">
        <property type="entry name" value="TIGR00266"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="360" mass="37486" checksum="85D88535E65492F3" modified="2019-10-16" version="1">MSNLNVSCPQCGKQYTAPANLAGRTIRCKACGASFAIPEDEDLISAEIIDVPFETQPPATGSLSVPPLPSQQGGSASGMPGGAHTSTSYAGTSSPVYADEIDYEIFGTESQYVEITLDPGETVIAEAGAMMYMDQGIEMQTVFGDPSQSGGGFWAKAMSAGKRALTGESLFMTTFTHQGAGRAKVAFGSPYPGRMLPLHLDELGGEIILQKDAFLCGAKGIKVDIAFQKKIGVGLFGGEGFIMQRLRGDGIAIAHAGGTMLHRVLKPNEQLRMDTGCLMGIGPSVRYDVQMVGGIKNTIFGGEGLFLATLTGPGPVWMQSLPFSRLAGRVIACAPGVGSTNKGEGSLLGGLGDMLMGDNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J134</accession>
    <name>A0A518J134_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_50730</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="105" mass="12046" checksum="544BB3ED62B19AE7" modified="2019-10-16" version="1">MINLRARTWLKYCVYSQLIAVPAVATIFMGVFGFVHRGFAVASLVVLICFGMSGAIVAVLKYYGRLCVVFTDTDLEIWMLRFWYNFERASGSETILLRGENEEYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J188</accession>
    <name>A0A518J188_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_51220</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Dockerin_1_rpt"/>
    </dbReference>
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        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028994">
        <property type="entry name" value="Integrin_alpha_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006626">
        <property type="entry name" value="PbH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00404">
        <property type="entry name" value="Dockerin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00710">
        <property type="entry name" value="PbH1"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="SSF69318"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="3545" mass="362414" checksum="4B40152B69BAB5D6" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1J1</accession>
    <name>A0A518J1J1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transketolase</fullName>
            <ecNumber evidence="8">2.2.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">tkt_2</name>
        <name evidence="8" type="ORF">Mal33_52390</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="2.2.1.1" evidence="8"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004802">
        <property type="term" value="F:transketolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd02012">
        <property type="entry name" value="TPP_TK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020826">
        <property type="entry name" value="Transketolase_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033248">
        <property type="entry name" value="Transketolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005474">
        <property type="entry name" value="Transketolase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02780">
        <property type="entry name" value="Transketolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00456">
        <property type="entry name" value="Transketolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00802">
        <property type="entry name" value="TRANSKETOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
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    <keyword evidence="6" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="3 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Transket_pyr" evidence="7">
        <location>
            <begin position="313"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV59211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="618" mass="67546" checksum="970F5A9B575C54B5" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1X3</accession>
    <name>A0A518J1X3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_53610</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="147" mass="16401" checksum="AEBF19FA5FFFF2AD" modified="2019-10-16" version="1">MIKKYIVRLSDTEREELKAIVKKLKGSSQKVRRALILLKADTEGPGWSDAKIAEALACRIQTVENLRKRLVTEGFDTALHGKPRLSAPREKTLDGKQEAKVIALRLGKPPKGFASWSLRLLADHVVELGIVDSISYETVRQTLKKTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1X4</accession>
    <name>A0A518J1X4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PEP-CTERM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_53650</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013424">
        <property type="entry name" value="PEP_exosort_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07589">
        <property type="entry name" value="PEP-CTERM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02595">
        <property type="entry name" value="PEP_exosort"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PEP-CTERM" evidence="1">
        <location>
            <begin position="274"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="303" mass="32222" checksum="7DA0FE3E0CF44EC1" modified="2019-10-16" version="1">MLSFTRKHDHISPIAPAFQKSTCLKTSLTICSRVHLRAWRLRQTQSGNIFRINRHNHLPTPPIRLSSALLFNYFTLKPKRGCMMLRTNLSLFLTCLCAISAQASISTDFDGVGTATSFTVFDSEIVTFSATFGAGPAGTDAPGDLGGTVENGQTFSDSFFDNASDSAFAISGSGATSTTSYISFNGGTAATVRLVGHNANAAQLDKFDNIMMSNTNLQIMAKDSNGNTLIVDFASAGFFDKTFAFAAGISSIELTNIDFGGAYATTLTSFSATATPEPSSMALLGLAGMGGTAVRRYRRKRAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J298</accession>
    <name>A0A518J298_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Amidohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_55000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    </evidence>
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</entry>
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
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                <person name="Kallscheuer N."/>
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                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
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                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
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                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
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    </dbReference>
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            <dbReference type="EMBL" id="QDV59473.1"/>
        </source>
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        <source>
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    </evidence>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 4">Mal33</strain>
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    </reference>
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            <dbReference type="EMBL" id="QDV59493.1"/>
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    </evidence>
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            <dbReference type="Proteomes" id="UP000316770"/>
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</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J2F3</accession>
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        <submittedName>
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    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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                <person name="Rast P."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="1 2">Mal33</strain>
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            <dbReference type="EMBL" id="QDV59515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="240" mass="26030" checksum="CF36B3FF1A54B812" modified="2019-10-16" version="1">MTCGPVVNPTGLPSWNNDYLAGSTIEVNSVVEDRPHDRSHAQRGSDSKNARMLWIDGVGGFLIVAGDEWLIGGPGAGSSVEINVQGDLSRRAAAVRRQGSDYVLQPLAPTRLQGEPLDRPTLLRTGDRFQLGSVVQFEFQKTHPLSSSARLNLVSRHRTQPRADGVILLADTCVIGPSQGAHIQCSHWTSDVILFVSGDDWRIRSEEPLVVDGTQIGQTAVLSPDCRIVGETLAMSMERL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IM31</accession>
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        <submittedName>
            <fullName evidence="3">Response regulator PleD</fullName>
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        <name evidence="3" type="primary">pleD_1</name>
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    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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                <person name="Overmann J."/>
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                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
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        <property type="entry name" value="Nucleotide_cyclase"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="159"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="299"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="343"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="514" mass="55281" checksum="74AE84C4A6EA4F1C" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMC7</accession>
    <name>A0A518IMC7_9BACT</name>
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        <submittedName>
            <fullName evidence="3">Multidrug resistance protein MdtN</fullName>
        </submittedName>
    </protein>
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        <name evidence="3" type="ORF">Mal33_01980</name>
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    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
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            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021842496" evidence="1">
        <location>
            <begin position="24"/>
            <end position="298"/>
        </location>
    </feature>
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        <location>
            <begin position="43"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="298" mass="33016" checksum="02599C8D76898FEE" modified="2019-10-16" version="1" precursor="true">MKPIAPLHLLIAIALLVGSTSHGQDRSQPSSVETDCLLMILDQVDLAAERDGLLTTLHARTGEDVAAGQLLFQLGDVESKARLEVARAELDQATIKAENQWNIRAAEIELAKNTKETELLDEVGRVPYLERYRAASNKDRSAAELKIAEATRREDLYARQVAEAELSVAEIDLEQRSSVSPFAGTIVKQFRFQSEWCRQGDPVVRILRMDRLTVQAIVNLRDIAPHQIIGMKASATFQIAGEQPIVMDNLTITRCSPEVDLDGNYLVWTVTDNRKLPAANGQPQWLLRPGISGTLTIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMG5</accession>
    <name>A0A518IMG5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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    <organism evidence="2 3">
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        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
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                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="DUF368"/>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="56"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
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            <end position="102"/>
        </location>
    </feature>
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        <location>
            <begin position="114"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="139"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="189"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="268"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="306" mass="32791" checksum="B1E1A4E813A51D82" modified="2019-10-16" version="1">MGAADSVPGVSGGTVALILGHYHQLVAAISHFDREALSLALAGKWRRLAEHIDLRFLIALGLGVGIAIVSLASLLHWLLENRLPGTLAVFMGLIVASIWIVARQIQRWSTTAWVAVLLGTAVGYLISSLSPLAGEPGLLYLFFSGVIAITAMILPGISGSFVLVLLGVYHHVIGLVKALPRGELTLEGLIQIIVFASGCAIGLAAFSRVLRWLLEHYQNVTFACLLGLMIGSLKRVWPLQQPTAETAAEKFSHRVFELVPISEWAQPLWPLLLLGIGAASFVLAAEAIAVRTYTPRDVDAKLDEGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMG6</accession>
    <name>A0A518IMG6_9BACT</name>
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        <submittedName>
            <fullName evidence="10">ClpA/B family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Mal33_02310</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036628">
        <property type="entry name" value="Clp_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004176">
        <property type="entry name" value="Clp_R_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001270">
        <property type="entry name" value="ClpA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018368">
        <property type="entry name" value="ClpA/B_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041546">
        <property type="entry name" value="ClpA/ClpB_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001943">
        <property type="entry name" value="UVR_dom"/>
    </dbReference>
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        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17871">
        <property type="entry name" value="AAA_lid_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02861">
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        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00300">
        <property type="entry name" value="CLPPROTEASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81923">
        <property type="entry name" value="SSF81923"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51903">
        <property type="entry name" value="CLP_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00870">
        <property type="entry name" value="CLPAB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50151">
        <property type="entry name" value="UVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Clp R" evidence="9">
        <location>
            <begin position="2"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="UVR" evidence="8">
        <location>
            <begin position="432"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="151"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="826"/>
            <end position="855"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="428"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV54281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="855" mass="95597" checksum="BF1268D4A035437C" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IML3</accession>
    <name>A0A518IML3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Lipoprotein-releasing system ATP-binding protein LolD</fullName>
            <ecNumber evidence="5">3.6.3.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">lolD_1</name>
        <name evidence="5" type="ORF">Mal33_02820</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.6.3.-" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="12"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="46"/>
            <end position="53"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV54329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="234" mass="25853" checksum="261A9FAA2AEC87EF" modified="2019-10-16" version="1">MNKTNEQPQPLLQCKGLRKVYPNGNVEALRGVDVEIFQGEYVAIMGTSGSGKSTLLCTLSGMDVPTSGEVLYRGKPLTQHGSLDRFRALELGFVFQSFYLLPTLTAIENVQVPMFEGPPRSSAEKHQRAHDLLERVGIGHRANHLPMRLSVGERQRVAIARSLANEPKLIFADEPTGNLDSRTTEEILAIFANLHETEGVTLVMVTHSGDVAAHAERTLHFQDGQIVKEENNRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMR6</accession>
    <name>A0A518IMR6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sporulation kinase D</fullName>
            <ecNumber evidence="3">2.7.13.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">kinD_1</name>
        <name evidence="3" type="ORF">Mal33_03280</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.13.3" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="2">
        <location>
            <begin position="195"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="404" mass="44184" checksum="EB9BB87B05D4FBE1" modified="2019-10-16" version="1">MNQTGLLPSISWNGSRWWLPLSTATANQLAQQFLQPNPDALRALLESDPSLRIWMLLECAASNNAALLTLSNLANQAPAALAAAFRDSNRQSDSPSDLQSFHPQWCELHRDATAWDSPERWLQVTGPVVPSAWQQTWPRLVDATNLPQTCPDFGGNKLDLARLLQTTDRAAATNAQLVKTLKAEKLAALKEFAYGLSHEINNPLANISTRAQSLARDESSPDRKRMLAAIVNQAMRAYEMIADVMFFANPPQPKITDDNEPEDVSELVRQIVDEFTTSCAIDGIAISSQITPDCRATIDRGQIADAIRSLLRNACEAIHPPGQIAVELVRADKMLRLRITDSGPGLNKRERRHAFDPFFSGREAGRGLGLGLCKAQRVIELAGGRIAIDSSPTGCVATAYMPAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMT5</accession>
    <name>A0A518IMT5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Probable nicotinate-nucleotide adenylyltransferase</fullName>
            <ecNumber evidence="6">2.7.7.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Deamido-NAD(+) diphosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Deamido-NAD(+) pyrophosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Nicotinate mononucleotide adenylyltransferase</fullName>
            <shortName evidence="6">NaMN adenylyltransferase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 8" type="primary">nadD</name>
        <name evidence="8" type="ORF">Mal33_03520</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 6">Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>ATP + H(+) + nicotinate beta-D-ribonucleotide = deamido-NAD(+) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22860"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57502"/>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
            <dbReference type="EC" id="2.7.7.18"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 6">Cofactor biosynthesis; NAD(+) biosynthesis; deamido-NAD(+) from nicotinate D-ribonucleotide: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the NadD family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.18" evidence="6"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00332"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004515">
        <property type="term" value="F:nicotinate-nucleotide adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02165">
        <property type="entry name" value="NMNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00244">
        <property type="entry name" value="NaMN_adenylyltr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004821">
        <property type="entry name" value="Cyt_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005248">
        <property type="entry name" value="NadD/NMNAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01467">
        <property type="entry name" value="CTP_transf_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00125">
        <property type="entry name" value="cyt_tran_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00482">
        <property type="entry name" value="TIGR00482"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 6" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="4 6" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CTP_transf_like" evidence="7">
        <location>
            <begin position="5"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV54398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="199" mass="21595" checksum="C2287176DABA54FF" modified="2019-10-16" version="1">MRIGILGGSFDPVHYGHLMLAERAREQLSLDKVLFVPAAMSPLKPTGPVASSEARVAMLQLAIGGNEAFEVSRVEIDRGGVSYTLDTVTAIREQFPQAELFLMMGADLVGQLGDWNQPEKIFAIAKPAIMNRGGYDAATAAEIEPFLTDSDSGQVAFLQMPQIELSSSELRDRVGAGKSIRYHTPRAVEESIRAEGLYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMX3</accession>
    <name>A0A518IMX3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_03870</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="161"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="195"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="228" mass="24756" checksum="C44089834E3BD279" modified="2019-10-16" version="1">MRSVGSRRRFGDSHDLGFACGRCGSRIANWVEFVWVCGCFHLPTPQISRRDSGQLAVGKRIATYGFDVTRHADREAGHRIPSGRTGALYRLGRRTGSSHRGPRDHGGQRARARRFQVALSVASECGIARAWAATPEGSRKRLAHPTGGIASAQPPANRCHALGVVMDVAVPPTFHCTAVGLWMSPFATSPFATLVSVFIGQWAILSFGACWQLALAVLAYRYRKDAPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IN68</accession>
    <name>A0A518IN68_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Mechanosensitive channel MscK</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">mscK_1</name>
        <name evidence="10" type="ORF">Mal33_04850</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MscS (TC 1.A.23) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011066">
        <property type="entry name" value="MscS_channel_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023408">
        <property type="entry name" value="MscS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025692">
        <property type="entry name" value="MscS_IM_dom1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12794">
        <property type="entry name" value="MscS_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="SSF50182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82689">
        <property type="entry name" value="SSF82689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="509"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="548"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="585"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="634"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="665"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="708"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="741"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="816"/>
            <end position="833"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="882"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="920"/>
            <end position="945"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="951"/>
            <end position="978"/>
        </location>
    </feature>
    <feature type="domain" description="MscS_TM" evidence="9">
        <location>
            <begin position="511"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="129"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="302"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV54530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1151" mass="127455" checksum="4762D3AB673E6089" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INB1</accession>
    <name>A0A518INB1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NAD(P)H-quinone oxidoreductase chain 4 1</fullName>
            <ecNumber evidence="4">1.6.5.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ndhD1</name>
        <name evidence="4" type="ORF">Mal33_05220</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="1.6.5.-" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042773">
        <property type="term" value="P:ATP synthesis coupled electron transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003918">
        <property type="entry name" value="NADH_UbQ_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001750">
        <property type="entry name" value="ND/Mrp_mem"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43507">
        <property type="entry name" value="PTHR43507"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00361">
        <property type="entry name" value="Proton_antipo_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="37"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="77"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="158"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="189"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="223"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="247"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="276"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="306"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="345"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="379"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="424"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="domain" description="Proton_antipo_M" evidence="3">
        <location>
            <begin position="176"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV54567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="485" mass="52688" checksum="90BC402EEDD23F78" modified="2019-10-16" version="1">MPELHFPWIEVSILVPLFGALWIHLLGNRESVLQHAIAICGVTLALTVGELVDFVSIGSFEAHDHWLFLDWLFQRDIFVVDELSAFQLPLAALIFLVTVMSTLRTKAPRFSLKLTLISESLVLATFSCRSSWTLIALLIAATIPPYLELRSRQRCTRIYVLHMAVFALLLVVGFAWLNHAGGSSSQALIAGALLTAAALLRSGIFPLHLWMTDLFEKATFGTAILFTTPLVGAYAVMRLVLPMAPSWALQSIAVLSLVTAVYGGAMALVQREARRMFCYLLLSQSSLVLVGLELVTPIGLTGALCMWLSVGLSLTGFGITLRCIEARISRVSLADYHGLARQMPMLSGFFLLTGLASIGFPATVGFVGMELLIEGAVDVYPLVGTMVVIAAALCGITVLMAYFRVFTGHHNRTLVPMHARPAERVAVLILTLLILGGGLVPQPGVASRYHAAEALTRQRQTNPMTEQQVGELEIETVAIGKHSAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IND4</accession>
    <name>A0A518IND4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_05510</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002105">
        <property type="entry name" value="Dockerin_1_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036439">
        <property type="entry name" value="Dockerin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045474">
        <property type="entry name" value="GEVED"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006626">
        <property type="entry name" value="PbH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007280">
        <property type="entry name" value="Peptidase_C_arc/bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00404">
        <property type="entry name" value="Dockerin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20009">
        <property type="entry name" value="GEVED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04151">
        <property type="entry name" value="PPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00710">
        <property type="entry name" value="PbH1"/>
        <property type="match status" value="13"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPC" evidence="2">
        <location>
            <begin position="749"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="domain" description="GEVED" evidence="3">
        <location>
            <begin position="5077"/>
            <end position="5158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1776"/>
            <end position="1797"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2477"/>
            <end position="2496"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="5005"/>
            <end position="5030"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="5008"/>
            <end position="5030"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV54596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="5320" mass="557068" checksum="ACB7A7003B15065E" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INM9</accession>
    <name>A0A518INM9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative S-adenosylmethionine-dependent methyltransferase/MSMEI_2290</fullName>
            <ecNumber evidence="1">2.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_06600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.1.1.-" evidence="1"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="343" mass="38341" checksum="58EB208AB5920E9F" modified="2019-10-16" version="1">MNHESLSIIHTIEVPCPLCGADESRPLHEVEDFTYGIPGRYTVVRCCGCRHLFLNPRPTDASLLDCYPQHYAPYHGGDDAAPEPSDCESSAADEPKSLLRRAIGSIPGLKRFLFWLGQENATFLPPSPVPGRSRLLEIGSADGKFLLAAQQAGWVVDGVEPSREAAQRSIDQGLDVQCGMFSEMEVADASRDAVVYWMVLEHVTDPAALLKESLRVLTPGGLLALSVPNAGAIERHVFGRYWLGYDAPRHLQNFTASQLKRLLREFGFEDPKIIHQPNTRYWYGSVAAWGGKYFPSHRWPQRWMDYFTTEPPAWMRWPLLLPGKLIAMLGCSGRITVVARKPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INP4</accession>
    <name>A0A518INP4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_06710</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the phD/YefM antitoxin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036165">
        <property type="entry name" value="YefM-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143120">
        <property type="entry name" value="SSF143120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="78" mass="8215" checksum="335A164575BA2F07" modified="2019-10-16" version="1">MATVSIEDAQSKLAELIHSMAPGEALIITDGSQPVACLTATDAPLPPTPRKPGTLAGTVTYMADDFDAPLDELRDYMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INW2</accession>
    <name>A0A518INW2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Oligopeptide transport ATP-binding protein OppF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">oppF</name>
        <name evidence="6" type="ORF">Mal33_07440</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015833">
        <property type="term" value="P:peptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013563">
        <property type="entry name" value="Oligopep_ABC_C"/>
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        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08352">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF52540"/>
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    </dbReference>
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        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4 6" id="KW-0067">ATP-binding</keyword>
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    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="20"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="53"/>
            <end position="60"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV54779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="339" mass="37042" checksum="3D914D21BB4B9E97" modified="2019-10-16" version="1">MNDSTAPLLAVENLKVHFPFRRGTLFAPEHGLIRAVDGVSFEIREGETLGLVGESGCGKSTTARAIARLNEPTSGSIKIEGHEICGLSESAMMPFRRTVQMVFQDPFASLNPRMTVGAIISEPLQIHGVLSNADRRLEVLRLMDLVGLNPRFLNRYPHEFSGGQRQRIGIARALAVRPKLILCDEPVSALDVSIQAQVINLMMDLQQKLGLAYLFIAHDLGIVRHIATRVGVMYLGRIVESANADELYNDPTHPYTRALLSAVPVPDPKVEAQRERIVLTGEVPSPDKSYPGCPFVDRCPDAQSECREIVPRLPASSHATACIVHDAQCRTASQPAAAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INX1</accession>
    <name>A0A518INX1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Planctomycete cytochrome C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Mal33_07580</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="Cyt_c_Planctomycete-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011444">
        <property type="entry name" value="DUF1549"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022655">
        <property type="entry name" value="DUF1553"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07635">
        <property type="entry name" value="PSCyt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07583">
        <property type="entry name" value="PSCyt2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PSD1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021966359" evidence="2">
        <location>
            <begin position="23"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="domain" description="PSCyt1" evidence="5">
        <location>
            <begin position="48"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="PSCyt2" evidence="3">
        <location>
            <begin position="175"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="domain" description="PSD1" evidence="4">
        <location>
            <begin position="544"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="403"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV54793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="835" mass="94004" checksum="4B39953BAE3449AC" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP17</accession>
    <name>A0A518IP17_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_08020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PlsC" evidence="1">
        <location>
            <begin position="62"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="411" mass="46670" checksum="26A27607D710A217" modified="2019-10-16" version="1">MVSVIVEKPYRFVPPHRGDWWPSMIQKFKLYERHLRDTDGVVDYELRNVDRLQESLRRGDGIMMAPNHSRYADPLVLGWLAKQARTHVFAMASWHLFNMGKFNAFSIQKMGAFSVFREGLDKQSIETAIDILVEARRPLVLFAEGATFRANDRLQPLLDGASLIARTAARRREKNSHGRVVVHPIAIKYVFQGDIYEWADKSLTAIEQRLTWEPNRHLPLRKRITHVADGLLALKEVQYLGSPQSGNVIQRQEYLTKALLQQVESKWKANAVDAADVGSVLNRVKAMRLQMFPELINDSTSPERKEAIRNDLRSLELAQQLASFPVGYLNEPPVTVTRVLETLENVEEAVFGKTSWPGPLKAIVDVGEAIEVPAERAPRKQEDPLMVEIAQQLQGMLNQLATEPRLLAADD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPE0</accession>
    <name>A0A518IPE0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative peptidyl-prolyl cis-trans isomerase</fullName>
            <ecNumber evidence="3">5.2.1.8</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ppiB_1</name>
        <name evidence="3" type="ORF">Mal33_09290</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="5.2.1.8" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000413">
        <property type="term" value="P:protein peptidyl-prolyl isomerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044016">
        <property type="entry name" value="Big_13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015919">
        <property type="entry name" value="Cadherin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044666">
        <property type="entry name" value="Cyclophilin_A-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625">
        <property type="entry name" value="PTHR45625"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19077">
        <property type="entry name" value="Big_13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49313">
        <property type="entry name" value="SSF49313"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="SSF50891"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="2">
        <location>
            <begin position="218"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1501"/>
            <end position="1521"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1536" mass="159448" checksum="CFFC0BA4A123AEFF" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPI0</accession>
    <name>A0A518IPI0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">50S ribosomal protein L21</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 6" type="primary">rplU</name>
        <name evidence="6" type="ORF">Mal33_09670</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 5">This protein binds to 23S rRNA in the presence of protein L20.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 50S ribosomal subunit. Contacts protein L20.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the bacterial ribosomal protein bL21 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01363">
        <property type="entry name" value="Ribosomal_L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036164">
        <property type="entry name" value="L21-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028909">
        <property type="entry name" value="L21p-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001787">
        <property type="entry name" value="Ribosomal_L21"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21349">
        <property type="entry name" value="PTHR21349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00829">
        <property type="entry name" value="Ribosomal_L21p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141091">
        <property type="entry name" value="SSF141091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00061">
        <property type="entry name" value="L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 5" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV54999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="103" mass="11563" checksum="2F98E51008E01323" modified="2019-10-16" version="1">MYAIFVDGGKQYRAEPGQEIDIDYRDVGQGESLDFPKVLAIGSDDGFKLGSPTVSGASVKVSVLGPKQGEKVYVEKFRRRQNSKRRTGHRQLYTRVRIESIEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPS7</accession>
    <name>A0A518IPS7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_10390</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038763">
        <property type="entry name" value="DHH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016877">
        <property type="entry name" value="UCP028235"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028235">
        <property type="entry name" value="UCP028235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64182">
        <property type="entry name" value="SSF64182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="320" mass="36024" checksum="8C44A5F3B91B81DF" modified="2019-10-16" version="1">MATSKKQYRLLTRSDFDGLVCAILLKEMGILGDIKFVHPKDMQDGIIEVTDNDILTNLPYVKGCHLCFDHHASEATRNEEVGSEDYILVPHADSAARVVYDYYGGKQRFPEISDDMMLAVDKADSAKFDLEEVLNPSGWGLLSFLMDARTGLGRFHDFRISNYHLMMELIDCCKNYSIQQILALPDVQERVDIYRAHEKLAKDQIRRCSTVYGNLIVLDLRDEETIYATNRFTIYSLFPQCNISMHVLWGKLQQNTVFTIGKSIFDRSCSTDVGELCLKYNGGGHTAAGTCQVAHEDSARVLDELIGQINEDAGITTSVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPU1</accession>
    <name>A0A518IPU1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Chorismate synthase</fullName>
            <shortName evidence="8">CS</shortName>
            <ecNumber evidence="4 8">4.2.3.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">5-enolpyruvylshikimate-3-phosphate phospholyase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 9" type="primary">aroC</name>
        <name evidence="9" type="ORF">Mal33_10610</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:21020"/>
            <dbReference type="ChEBI" id="CHEBI:29748"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57701"/>
            <dbReference type="EC" id="4.2.3.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>FMNH2</name>
            <dbReference type="ChEBI" id="CHEBI:57618"/>
        </cofactor>
        <text evidence="8">Reduced FMN (FMNH(2)).</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 7/7.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the chorismate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="4.2.3.5" evidence="4 8"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004107">
        <property type="term" value="F:chorismate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd07304">
        <property type="entry name" value="Chorismate_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00300">
        <property type="entry name" value="Chorismate_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000453">
        <property type="entry name" value="Chorismate_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035904">
        <property type="entry name" value="Chorismate_synth_AroC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020541">
        <property type="entry name" value="Chorismate_synthase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21085">
        <property type="entry name" value="PTHR21085"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01264">
        <property type="entry name" value="Chorismate_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001456">
        <property type="entry name" value="Chorismate_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103263">
        <property type="entry name" value="SSF103263"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00033">
        <property type="entry name" value="aroC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00788">
        <property type="entry name" value="CHORISMATE_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 8" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0274">FAD</keyword>
    <keyword evidence="8" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0288">FMN</keyword>
    <keyword evidence="7 8 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-0521">NADP</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="8">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="125"/>
            <end position="127"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="294"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="309"/>
            <end position="313"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="335"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV55092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="374" mass="39881" checksum="09EECEB2FC46113B" modified="2019-10-16" version="1">MTGNSFGQALRITTAGESHGPGNVVIIDGVPAGIPFSVDDLLPDLARRRPGQSKIVTQRKESDEPEILAGVFEGRTTGTSLAILIRNQDQRSKDYSDIKDKYRPGHADFTFDQKYGFRDYRGGGRSSARETTARVAAGALAKKILAEAFGGRVLGYVTQVGDLKAEIADPASVTLQQVEEFADGQPNIVRCPDEAVAQQMIAKIEEVRKAGDSIGGAAEIVAANIPAGLGEPVFDKLKADLAKALFSLPAVLGVEYGIGFGCVTMRGSEHNDLFTTGEDGQITTKSNRHGGMLGGISTGLPIVLRAAVKPTSSLPIEQSTVTSSGEATTIRTRGRHDPCLLPRFIPMAEAMVAIVIADHWLRWRAQNAWSPGTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPV0</accession>
    <name>A0A518IPV0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glutamate synthase [NADPH] large chain</fullName>
            <ecNumber evidence="7">1.4.1.13</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">gltA_2</name>
        <name evidence="7" type="ORF">Mal33_10870</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the glutamate synthase family.</text>
    </comment>
    <dbReference type="EC" id="1.4.1.13" evidence="7"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004355">
        <property type="term" value="F:glutamate synthase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006537">
        <property type="term" value="P:glutamate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02808">
        <property type="entry name" value="GltS_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024188">
        <property type="entry name" value="GltB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043578">
        <property type="entry name" value="GltB_archl_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002932">
        <property type="entry name" value="Glu_synthdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01645">
        <property type="entry name" value="Glu_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00355">
        <property type="entry name" value="Rieske"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500061">
        <property type="entry name" value="GOGAT_lg2_archl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006429">
        <property type="entry name" value="GOGAT_lg_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="SSF50022"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
        <property type="entry name" value="RIESKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rieske" evidence="6">
        <location>
            <begin position="12"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR006429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV55118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="547" mass="59204" checksum="5ED7C2BF5AFD48C3" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQ10</accession>
    <name>A0A518IQ10_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_11550</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022087283" evidence="2">
        <location>
            <begin position="24"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="426"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="454" mass="49665" checksum="3F1C96F7564DB144" modified="2019-10-16" version="1" precursor="true">MGRRFVPLLLICATLSQSTNLLACPFCTAVSQTLRQEMASMDAVVVAEATEAIEPSDTGEVELTVKVVLKGEKLVKVDQRVKSIYFGKAEKGRRFMLTGVDPPELMWSSPLPLTERSEDYLLKLTKLPDDDVERLVFFQEFLEDEEDLLARDTYDEFAVAPYSAVKALGPKMHHDQLIEWIKDPEIASDRRRLYLTMLGVCGDKKDVPMLEAMLTSTQKSTRGGLDALIACYLTLNGAEGLPVVNKLFLDNKKAEYADTYAAIMALRFHGTETDVIPKEQLVSSLHHVLKRPQLADLVIPDLARWGDWSQIDALVELFKTAEAGNNWVRVPVINYLRACPLPEAAAALVELEKVDPAAVRRANTFFPVPAADAPKKDAETSQISDSAASGLVQVFDSGKPLAAATAALPQVGRSATAISAVNPLRLLFVSSITATSLTILIWLVISGGTLPAQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQ68</accession>
    <name>A0A518IQ68_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidase family M50</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_12080</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001193">
        <property type="entry name" value="MBTPS2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13325">
        <property type="entry name" value="PTHR13325"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="149"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="186"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="257"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="282"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="355"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="383"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="427"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="735" mass="80440" checksum="3529475381A785AF" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQA5</accession>
    <name>A0A518IQA5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">1-deoxy-D-xylulose-5-phosphate synthase</fullName>
            <ecNumber evidence="8">2.2.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">1-deoxyxylulose-5-phosphate synthase</fullName>
            <shortName evidence="8">DXP synthase</shortName>
            <shortName evidence="8">DXPS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 10" type="primary">dxs</name>
        <name evidence="10" type="ORF">Mal33_12560</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>D-glyceraldehyde 3-phosphate + H(+) + pyruvate = 1-deoxy-D-xylulose 5-phosphate + CO2</text>
            <dbReference type="Rhea" id="RHEA:12605"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57792"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="2.2.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="8">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
        <text evidence="8">Binds 1 thiamine pyrophosphate per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Metabolic intermediate biosynthesis; 1-deoxy-D-xylulose 5-phosphate biosynthesis; 1-deoxy-D-xylulose 5-phosphate from D-glyceraldehyde 3-phosphate and pyruvate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 8">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the transketolase family. DXPS subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.7" evidence="8"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00064">
        <property type="reaction ID" value="UER00091"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008661">
        <property type="term" value="F:1-deoxy-D-xylulose-5-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052865">
        <property type="term" value="P:1-deoxy-D-xylulose 5-phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02007">
        <property type="entry name" value="TPP_DXS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00315">
        <property type="entry name" value="DXP_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005477">
        <property type="entry name" value="Dxylulose-5-P_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020826">
        <property type="entry name" value="Transketolase_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033248">
        <property type="entry name" value="Transketolase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43322">
        <property type="entry name" value="PTHR43322"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13292">
        <property type="entry name" value="DXP_synthase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02780">
        <property type="entry name" value="Transketolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00204">
        <property type="entry name" value="dxs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00802">
        <property type="entry name" value="TRANSKETOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0784">Thiamine biosynthesis</keyword>
    <keyword evidence="6 8" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="4 8 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Transket_pyr" evidence="9">
        <location>
            <begin position="319"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Thiamine pyrophosphate binding" evidence="8">
        <location>
            <begin position="115"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Thiamine pyrophosphate binding" evidence="8">
        <location>
            <begin position="148"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="74"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="176"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="287"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="370"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV55286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="627" mass="68772" checksum="6930D5A2EF67D3C5" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQC1</accession>
    <name>A0A518IQC1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_12680</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="113" mass="12191" checksum="1E00EFBCDE5932F3" modified="2019-10-16" version="1">MSSENKIDIQRVLILIVAVVLLAWGGIGELMSDRLGQSVSNAALLRVGFVLFACWVAYPVVRRPTAWLAPGATAIGVILIGAAFFNPKLLIVLIPLFGSLLAFGAFIRYFRSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQE8</accession>
    <name>A0A518IQE8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">N-succinylglutamate 5-semialdehyde dehydrogenase</fullName>
            <ecNumber evidence="9">1.2.1.71</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">astD</name>
        <name evidence="9" type="ORF">Mal33_12740</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.71" evidence="9"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043824">
        <property type="term" value="F:succinylglutamate-semialdehyde dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006527">
        <property type="term" value="P:arginine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07095">
        <property type="entry name" value="ALDH_SGSD_AstD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017649">
        <property type="entry name" value="SuccinylGlu_semiald_DH_AstD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11699:SF197">
        <property type="entry name" value="PTHR11699:SF197"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03240">
        <property type="entry name" value="arg_catab_astD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0056">Arginine metabolism</keyword>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="2 6 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="8">
        <location>
            <begin position="40"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="51"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="274"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV55304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="519" mass="54406" checksum="5C7A788ADFD9CDA1" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQF3</accession>
    <name>A0A518IQF3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Rod-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_12960</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019301">
        <property type="entry name" value="Flagellar_prot_FlgJ_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10135">
        <property type="entry name" value="Rod-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rod-binding" evidence="2">
        <location>
            <begin position="56"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="110" mass="12190" checksum="162EABA34745B164" modified="2019-10-16" version="1">MISGIHNQSLTNQAAAHSKSNLQQSGNSLQAAPADEMQTLFRDFVGKTLFGELMSSMHKTHDKAAYFHGGQAEEIFQQQLDQVMVDEITESSASQIADPMFELFQLSRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQJ3</accession>
    <name>A0A518IQJ3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Thiamine biosynthesis protein ThiF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_13270</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019781">
        <property type="term" value="F:NEDD8 activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045116">
        <property type="term" value="P:protein neddylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030468">
        <property type="entry name" value="Uba3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953">
        <property type="entry name" value="PTHR10953"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953:SF6">
        <property type="entry name" value="PTHR10953:SF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="SSF69572"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ThiF" evidence="1">
        <location>
            <begin position="18"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="221" mass="24031" checksum="7329D5143B5FFCA5" modified="2019-10-16" version="1">MSTIENRFERQSQLVPADRLADVTATVIGVGAIGRQVAMQLAYIGVPSIQLIDFDAVDLSNTTTQGYRKHEIGWAKPFACSQAISEIAPSIEVIRVEDRFRPRLEIGNAVFCCVDSITARTAIWKSVQGRSAFWADGRMLGEVLRVLAVTDGASSTHYDSTLFTASEAQQGTCTSRSTIYAASIAAGLTVHQLTRWLRGIPIDADTSVNLLSGEWSIHDTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQM5</accession>
    <name>A0A518IQM5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative periplasmic serine endoprotease DegP-like</fullName>
            <ecNumber evidence="4">3.4.21.107</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">mucD_2</name>
        <name evidence="4" type="ORF">Mal33_13600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.4.21.107" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001940">
        <property type="entry name" value="Peptidase_S1C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13180">
        <property type="entry name" value="PDZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00834">
        <property type="entry name" value="PROTEASES2C"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022169352" evidence="2">
        <location>
            <begin position="28"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="3">
        <location>
            <begin position="265"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV55389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="498" mass="53572" checksum="7D4339B9A2DF2570" modified="2019-10-16" version="1" precursor="true">MRNHFSKLVSLAVFGLSASLAMSTLVAVEPKARDRATEILSANSLSSVVRQVADDVSPSIVTVYALRGPRMTAPMRWRKEAKLPQPFHSPNHQHAASSNSHSADDQGSGVIIDRRGCVLTCSHVVENADAVFVRTADGRKLHAEAVICDPQSDIAIIKLESAENLPEAKLADSDDLSVGDWVVSLASPYDLQRSVSAGIISSTQRWVASSPHPLIQNDAATNPGSSGGALLNLRGEVVGIIEGALTTSGEFQGIGLATPINTARDIAEQLQTKGYVERGYFGFQTQPLTPEMASLIDSSVNAGLYVKDVQRNSPANHAGLREGDVITKFDGKPINQSFDPATLTADTEPGKSHIMSVLREHKVVEIEMRMQQPPREVGPIQSEMSPNGPFEYLDSSLGLGLSSLNTSLINELELPGDAHGALITQVVFGSDAYREGVAAGMAIARVNDTTIHDVDEYREVTNKLDREKPVLLLLQSNQGKHLVMLHTSRKENDGKGKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQQ0</accession>
    <name>A0A518IQQ0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transcription termination factor Rho</fullName>
            <ecNumber evidence="6">3.6.4.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">ATP-dependent helicase Rho</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rho</name>
        <name evidence="10" type="ORF">Mal33_13890</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homohexamer. The homohexamer assembles into an open ring structure.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the Rho family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.-" evidence="6"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008186">
        <property type="term" value="F:ATP-dependent activity, acting on RNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006353">
        <property type="term" value="P:DNA-templated transcription, termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01884">
        <property type="entry name" value="Rho"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011113">
        <property type="entry name" value="Rho_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004665">
        <property type="entry name" value="Term_rho"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46425">
        <property type="entry name" value="PTHR46425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07497">
        <property type="entry name" value="Rho_RNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51856">
        <property type="entry name" value="RHO_RNA_BD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 6" id="KW-0347">Helicase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="1 6" id="KW-0806">Transcription termination</keyword>
    <feature type="domain" description="Rho RNA-BD" evidence="9">
        <location>
            <begin position="64"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="181"/>
            <end position="186"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="193"/>
            <end position="198"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="224"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV55416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="439" mass="48700" checksum="72652842F49E72CB" modified="2019-10-16" version="1">MAKKKRSYRGRSGSGNESNSNGNGGGGGGKGRVSRRRRRPSDGNNNANRQPEGDLPPVDDDAPLEEGIGLLEMHPNGYGFLRSPGNNFTRDRSDPFVPGTMIEKFGLREGVMIRGMVQPGRRHQGPRIREILDVDGITPDEYSEVKNFDSLTAINPEQWLRLEIGQKPLTNRVIDLLAPLGKGQRSLIVAPPRSGKTVMLQNISSGIAQNHPDVKLIVLLIDERPEEVTDMKRHVVGGEVIASSLDMDVDSHVRLSQLVIERCKRLAEMGQDVFLLLDSITRLARAFNKWVGQTGRGRATMTGGLDVKAMDIPKKLFATARAFQEGGSLTIVGTALVDTNSRMDEAIFQEFKGTGNMEVVLDRRLADRRVWPSIDISQSGTRREELLHDEETYEAVTMLRRTLSEMHHVDAMEQLTKQLGRFETNEDFIKLISGAKLTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQU1</accession>
    <name>A0A518IQU1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Resolvase/invertase-type recombinase catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_14410</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000150">
        <property type="term" value="F:DNA strand exchange activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006119">
        <property type="entry name" value="Resolv_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036162">
        <property type="entry name" value="Resolvase-like_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00239">
        <property type="entry name" value="Resolvase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53041">
        <property type="entry name" value="SSF53041"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Resolvase/invertase-type recombinase catalytic" evidence="1">
        <location>
            <begin position="9"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="93" mass="10226" checksum="D88EFB7D54AEDAA8" modified="2019-10-16" version="1">MLVSNSHECELIYEYTKIESGNRNGHQNLPKALTHARKIGGTLVIAKLARLARNVAFTATEMERGTNFVAVDNTSANFLTIHVLAAVAEDETR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQV6</accession>
    <name>A0A518IQV6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_14430</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="122" mass="13739" checksum="970FDB20FEDCEC5D" modified="2019-10-16" version="1">MNSSTTLIRQIHPSFVQDGRITSQAFRPTPKDEDMLSTYDGDQIDAKSAWKHYTESLGHVSDGALGVSVSECEALDLKVTSDPESFPEHVLIDFSGHGRKQIEKRAKKLKLHAETRDWLFQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQZ9</accession>
    <name>A0A518IQZ9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Formyltransferase/hydrolase complex subunit D</fullName>
            <ecNumber evidence="3">2.3.1.101</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">fhcD_2</name>
        <name evidence="3" type="ORF">Mal33_14920</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.3.1.101" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030270">
        <property type="term" value="F:formylmethanofuran-tetrahydromethanopterin N-formyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.520">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002770">
        <property type="entry name" value="ForMFR_H4MPT_ForTrfase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023447">
        <property type="entry name" value="ForMFR_H4MPT_ForTrfase_fd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022667">
        <property type="entry name" value="ForMFR_H4MPT_ForTrfase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01913">
        <property type="entry name" value="FTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02741">
        <property type="entry name" value="FTR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55112">
        <property type="entry name" value="SSF55112"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FTR" evidence="1">
        <location>
            <begin position="7"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="domain" description="FTR_C" evidence="2">
        <location>
            <begin position="156"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="307" mass="33115" checksum="13EF505B77A1E4F6" modified="2019-10-16" version="1">MPDLKTLVEDTYAEGFRGIYGEVLITAHDEKWLRHCVNAVTGHASSTIMCDCEAGVAQWIGPAAAAANKTPDGRPGAIVQFHVPRFRKNREKHLERVMLARISQNVLTCPTARCFNEIDSDDYFKLGRKVAMFGDRHQFRDQRYGEKGWVIPILAGEFFLSRRFGFRDGVMGGNLWFMAASADAALSAAERAAASVDACPDVVTTFPGGVASSGSKAGSSYDFLIAATYAEYCPTLKEKLGDISKVPAGVASITEIIINGKDLDAIKVATKAAIAAAAPTPDLVRITAGNYGGRLGKSFVHLHELID</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IR44</accession>
    <name>A0A518IR44_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_15410</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025738">
        <property type="entry name" value="BatD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40940">
        <property type="entry name" value="PTHR40940"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021947230" evidence="3">
        <location>
            <begin position="29"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="498"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="440"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV55564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="618" mass="66761" checksum="A37470DE6D79047E" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRJ4</accession>
    <name>A0A518IRJ4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cytidylate kinase</fullName>
            <shortName evidence="8">CK</shortName>
            <ecNumber evidence="8">2.7.4.25</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Cytidine monophosphate kinase</fullName>
            <shortName evidence="8">CMP kinase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">cmk_2</name>
        <name evidence="8" type="synonym">cmk</name>
        <name evidence="10" type="ORF">Mal33_16910</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + CMP = ADP + CDP</text>
            <dbReference type="Rhea" id="RHEA:11600"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58069"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.25"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 8">
            <text>ATP + dCMP = ADP + dCDP</text>
            <dbReference type="Rhea" id="RHEA:25094"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57566"/>
            <dbReference type="ChEBI" id="CHEBI:58593"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.25"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the cytidylate kinase family. Type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.25" evidence="8"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036430">
        <property type="term" value="F:CMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036431">
        <property type="term" value="F:dCMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006220">
        <property type="term" value="P:pyrimidine nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02020">
        <property type="entry name" value="CMPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00238">
        <property type="entry name" value="Cytidyl_kinase_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003136">
        <property type="entry name" value="Cytidylate_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011994">
        <property type="entry name" value="Cytidylate_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02224">
        <property type="entry name" value="Cytidylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00017">
        <property type="entry name" value="cmk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Cytidylate_kin" evidence="9">
        <location>
            <begin position="3"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="7"/>
            <end position="15"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV55712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="219" mass="23903" checksum="15AD2EE98316B117" modified="2019-10-16" version="1">MVITIDGPAGAGKSSVARKLASRLGFHFLDTGAMYRTVTHVAMQKGVDLGDSAAVETLAAALEIRLENDRVWADGCDVSVSIRTPEVTRNIRYVADIASVRQILNHKQRSLVVSNDYVTEGRDQGTEVFPDATCKIFLTASPEERARRRQRQLLANGQEIAVEQLLAEQNLRDAQDQNRDVGRLVAADDAITVSTDGMDEAQVVDKLESLVRAKLPSDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRN8</accession>
    <name>A0A518IRN8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Thioredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">trxA_3</name>
        <name evidence="3" type="ORF">Mal33_17230</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="2">
        <location>
            <begin position="27"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="134"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="156" mass="16780" checksum="BDF115B54C3C9CDC" modified="2019-10-16" version="1">MNKIMGIGLLALIVYYGYNHYSSDGLAGITGGYSDAAFEKQIEGPGLVLVKFGAPWCGPCRMIDEELEHVTGNVDVVKINIDRNRALASKFKVSGIPHTVIFRDGKPLGQFTGYRDAKAISSWARQFGSEVAPVQNASTGGSKLQPNGIKTNPYAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRS2</accession>
    <name>A0A518IRS2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glucose-6-phosphate 1-dehydrogenase</fullName>
            <shortName evidence="5">G6PD</shortName>
            <ecNumber evidence="5">1.1.1.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 9" type="primary">zwf</name>
        <name evidence="9" type="ORF">Mal33_17610</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>D-glucose 6-phosphate + NADP(+) = 6-phospho-D-glucono-1,5-lactone + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:15841"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57955"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:61548"/>
            <dbReference type="EC" id="1.1.1.49"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the glucose-6-phosphate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.49" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00408"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004345">
        <property type="term" value="F:glucose-6-phosphate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00966">
        <property type="entry name" value="G6PD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001282">
        <property type="entry name" value="G6P_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019796">
        <property type="entry name" value="G6P_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022675">
        <property type="entry name" value="G6P_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022674">
        <property type="entry name" value="G6P_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23429">
        <property type="entry name" value="PTHR23429"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02781">
        <property type="entry name" value="G6PD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00479">
        <property type="entry name" value="G6PD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000110">
        <property type="entry name" value="G6PD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00079">
        <property type="entry name" value="G6PDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00871">
        <property type="entry name" value="zwf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00069">
        <property type="entry name" value="G6P_DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="1 5" id="KW-0313">Glucose metabolism</keyword>
    <keyword evidence="2 5" id="KW-0521">NADP</keyword>
    <keyword evidence="3 5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G6PD_N" evidence="7">
        <location>
            <begin position="12"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="G6PD_C" evidence="8">
        <location>
            <begin position="194"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="244"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="49"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="91"/>
            <end position="92"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="152"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 6">
        <location>
            <position position="186"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="220"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="239"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="334"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV55782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="488" mass="55290" checksum="9280629721998629" modified="2019-10-16" version="1">MVRDNDMPSTIVIFGASGDLTSRKLIPALFRLFQKKRLPEGTRIVGVSRSDFSDEQWRNQLGETTEKFLPASFTAEDWKQFCQHVYYRPGDITKADDFVALGKHLDELEGAACDRVYYLSTSPRLYESAITLMGQAGLADESAGSRRVIIEKPFGTDLASAEALNQSIHKSFHENQIYRIDHYLGKETVQNLFALRFANTIFEPLWNRNYIDHVQITVAEEVVIGRRGGYYDTSGILRDMFQNHLLQLMMITAMEAPARYDANLVRDEKVKVLHSVRPMSGSDFACNTLRGQYQGYLQEDGVPAGSQTATFAALKLYIDNWRWKGVPFYLRSGKAMSCRTTQIVIQFRSPPHLLFPSGKMRTPEANQLVIQVQPAEGLQMYFQSKVPDTEMKTRTSHFDFRFQDAGPDGMPDAYQRLLMDAVNGDASLFARSDEVELAWSIIDPIINAWGSAAAPDLHVYEPGLWGPTESSEWMQGQKRSWFDVCPVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRY0</accession>
    <name>A0A518IRY0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">tRNA N6-adenosine threonylcarbamoyltransferase</fullName>
            <ecNumber evidence="6">2.3.1.234</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">N6-L-threonylcarbamoyladenine synthase</fullName>
            <shortName evidence="6">t(6)A synthase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">tRNA threonylcarbamoyladenosine biosynthesis protein TsaD</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 8" type="primary">tsaD</name>
        <name evidence="8" type="ORF">Mal33_18100</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>adenosine(37) in tRNA + L-threonylcarbamoyladenylate = AMP + H(+) + N(6)-L-threonylcarbamoyladenosine(37) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:37059"/>
            <dbReference type="Rhea" id="RHEA-COMP:10162"/>
            <dbReference type="Rhea" id="RHEA-COMP:10163"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:73682"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74418"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.3.1.234"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="6">Binds 1 Fe(2+) ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the KAE1 / TsaD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.234" evidence="6"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061711">
        <property type="term" value="F:N(6)-L-threonylcarbamoyladenine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002949">
        <property type="term" value="P:tRNA threonylcarbamoyladenosine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01445">
        <property type="entry name" value="TsaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000905">
        <property type="entry name" value="Gcp-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017861">
        <property type="entry name" value="KAE1/TsaD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017860">
        <property type="entry name" value="Peptidase_M22_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022450">
        <property type="entry name" value="TsaD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735">
        <property type="entry name" value="PTHR11735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735:SF6">
        <property type="entry name" value="PTHR11735:SF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00814">
        <property type="entry name" value="TsaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00789">
        <property type="entry name" value="OSIALOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00329">
        <property type="entry name" value="gcp_kae1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03723">
        <property type="entry name" value="T6A_TsaD_YgjD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01016">
        <property type="entry name" value="GLYCOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 8" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="4 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 6" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="TsaD" evidence="7">
        <location>
            <begin position="24"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="134"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="280"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="308"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV55831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="340" mass="35327" checksum="4D576A55ACFE7BA6" modified="2019-10-16" version="1">MIILTIESTCDETAAAVIASGPHVLGAAVATQTELHARFQGVVPEVAARAHVQRILPVIDEAIRQADIDPADLDAIAVANTPGLAGSLMVGLTAAKTLAVAWNKPLVAVNHLQAHIYACQMSDPGEIYPCVGLIVSGGHTSLYACHSATELDYLGGTIDDAAGEAFDKVGAMLGLPFPGGPSVSRAAAAGNPKAHDFPRSLVGEDHLNFSFSGLKTAVRYCLVGPGKQDFSQLDLSEQQLADLCASFEQAVVDCLVAKSRQAIRQTGFSKLCVGGGVAANGRLRAALAEAADRDGFGLVIAPPDLCTDNAVMGAVALEQIERHGYADLDVDIHPGLQRGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IS56</accession>
    <name>A0A518IS56_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Neutral zinc metallopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_19060</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007395">
        <property type="entry name" value="Zn_peptidase_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36434">
        <property type="entry name" value="PTHR36434"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04298">
        <property type="entry name" value="Zn_peptidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="144"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="197"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="225" mass="24358" checksum="C5B8907A0C16E45A" modified="2019-10-16" version="1">MYFDPIWFLFVIPPMLLAMFAQWRVKSAYHEMSQMPARMTGFQAARAMLDSAGLQQIGIEQTPGELSDHYDPRAKVLRLSSNVYGGNSMAAVGIACHEAGHAMQDAMHYAPLVIRNAAVPAANIGSGLGGTVAMVGLAFGLQPLVWVGVIAFAAVAFFQVINLPVEFDASNRAKHQLVAQGIIAERDLPFVSKVLNAAALTYVAATLQSLMTLAYFLFRALGDRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISG4</accession>
    <name>A0A518ISG4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Endo-1,4-beta-xylanase Z</fullName>
            <ecNumber evidence="2">3.2.1.8</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">xynZ_1</name>
        <name evidence="2" type="ORF">Mal33_20160</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.2.1.8" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031176">
        <property type="term" value="F:endo-1,4-beta-xylanase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045493">
        <property type="term" value="P:xylan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000801">
        <property type="entry name" value="Esterase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00756">
        <property type="entry name" value="Esterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0858">Xylan degradation</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021709725" evidence="1">
        <location>
            <begin position="26"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="241" mass="26843" checksum="F3BF42D2EB2C9D95" modified="2019-10-16" version="1" precursor="true">MRFLTCLLFVVSGAVCLVVPAAADAADQAAVHLDAKVEVQMDYLLYLPKDYDQKKAWPLVLFLHGAGERGDDLNLVKMHGPPRLIEEGKEFPFIVVSPQCPKGRWWREFELTALLDDVIATHNVDQDRVYVTGLSMGGFGSWGLAAFSPDRFAAIAPICGGGEPRSTRNFKHVPVWAFHGAKDTAVPLERTQAMIDALERQGAEPKLTIYPEAGHDSWTETYNNPAFYEWLLAQKRVAEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISJ5</accession>
    <name>A0A518ISJ5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_20400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="660" mass="71890" checksum="8699D51F79A0FB14" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISU3</accession>
    <name>A0A518ISU3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">todS</name>
        <name evidence="9" type="ORF">Mal33_21370</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004673">
        <property type="term" value="F:protein histidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007892">
        <property type="entry name" value="CHASE4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05228">
        <property type="entry name" value="CHASE4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="280"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="8">
        <location>
            <begin position="302"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="516"/>
            <end position="630"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV56158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="635" mass="69703" checksum="E2CDCCE72EBD424C" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISW4</accession>
    <name>A0A518ISW4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_21670</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010869">
        <property type="entry name" value="DUF1501"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07394">
        <property type="entry name" value="DUF1501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="485" mass="53429" checksum="7E8C3E1E3B367EDC" modified="2019-10-16" version="1">MSIFADPTAPRSIVRRDFLRQLSAAGTAALAAGAPRALASEAGGAVEHPRPTADACILLWMGGGMAAPDTFDPKRYLPYKPGLKVADMLSTFPAIDTAVDSIKICEGLENIAGVLDQGTLIRSHVQPDLGSILHSRHQYHWHTGYVPPQTVAAPHIGAWMSRVLGPRNDVMPAFINIGQRLEGVGESEELKAFTTAGFFGSEFGPMNLPYPDQAAVSVRPPKGMQAQRFADRNRLFRRLVDASPNRDFMSDYQQESMLRSMDSAYRLLSSRDRQAFDITREPKESFDRYNTGRFGQGCLLARRLVESGARFVEVTTEYVPFLHWDTHNDGHVTLQRMHREIDRPVAQLITDLQQRGLLDRTLVILASEFSRDALMEGQPGSNANDQATAKVDVLSELKHYGLHRHFTGGASVLMFGGGMKQGFLYGATAPERPLMAIENPVSIEDLHATIMTAMGISPQTGFDIEGRPFYVTEDGKGRAVQDLFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IT00</accession>
    <name>A0A518IT00_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">2-dehydropantoate 2-reductase</fullName>
            <ecNumber evidence="2">1.1.1.169</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Ketopantoate reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_21990</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>(R)-pantoate + NADP(+) = 2-dehydropantoate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:16233"/>
            <dbReference type="ChEBI" id="CHEBI:11561"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15980"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.169"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; (R)-pantothenate biosynthesis; (R)-pantoate from 3-methyl-2-oxobutanoate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the ketopantoate reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.169" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00028">
        <property type="reaction ID" value="UER00004"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008677">
        <property type="term" value="F:2-dehydropantoate 2-reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015940">
        <property type="term" value="P:pantothenate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003710">
        <property type="entry name" value="ApbA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013752">
        <property type="entry name" value="KPA_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013332">
        <property type="entry name" value="KPR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02558">
        <property type="entry name" value="ApbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08546">
        <property type="entry name" value="ApbA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00745">
        <property type="entry name" value="apbA_panE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0566">Pantothenate biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ApbA" evidence="3">
        <location>
            <begin position="8"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="domain" description="ApbA_C" evidence="4">
        <location>
            <begin position="185"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV56218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="319" mass="35110" checksum="13FC4FFBCD3426A5" modified="2019-10-16" version="1">MSSKRSYAIIGTGALGGYYGGLLARAGFDVHFLLRSDFDHVQQHGLQIDSKNGNFHLPQVNAYRSAAEMPACDVTIVAIKTTANQQLAEILAATTREGGVVLVLQNGLHVEADSAAVVGPDRVLGGCCFLCSNKVGPGHIDHIDYGRIAFGEYRADGSVRPISERTREIEADLKLASIPAEAVDDLIKVRWQKLMWNIPFNGLSVVLDASTAEIMNHPASEALAEQIIRDVRAAAMQCGKSIDEAFVNKMMNDTRAMVPYDSSMRVDFKQGRPMEVEAIVGNPLRELQRHGGQSPRLEMLYQQLTFFDRRRTKQHTSRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITF4</accession>
    <name>A0A518ITF4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_23570</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1203" mass="128605" checksum="D863867B2C1B7B66" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITN1</accession>
    <name>A0A518ITN1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">TPR repeat-containing protein YfgC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">yfgC_2</name>
        <name evidence="8" type="ORF">Mal33_24360</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the peptidase M48 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001915">
        <property type="entry name" value="Peptidase_M48"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01435">
        <property type="entry name" value="Peptidase_M48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1 6" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase_M48" evidence="7">
        <location>
            <begin position="68"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV56446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="275" mass="29768" checksum="42707F20F9B991DA" modified="2019-10-16" version="1">MKEINRRQCLGGLLVTGAAAGVASCGCRSAPYTGRKQLLIYPEGKEMSLGSEAYGEVTKETPLSENPQYTAMVQRVGERIAAVAGRSDFEWEFKTLQSEEQNAFCLPGGKVAVYEGILPVCQNEAGLAVVMGHEIAHALARHGGERMSQNAAVQGVQTAASYILQNQEETKKEMIFKAYGMATEYGVLLPFSRKHESEADEIGITLMANAGYDPAEAPKFWTRFGAAGTGEKQPEFLSTHPSDERRSQDLEALLPGARELYEQAAEKVGLGEAIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITT4</accession>
    <name>A0A518ITT4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_24900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="34" mass="3635" checksum="567FBB9EFC8D012C" modified="2019-10-16" version="1">MWKSEIPTSIATMIAMHIGLFDLGGIFLGQLGVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITU9</accession>
    <name>A0A518ITU9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_25040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010064">
        <property type="entry name" value="HK97-gp10_tail"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04883">
        <property type="entry name" value="HK97-gp10_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="151" mass="16669" checksum="543551E8F7C70007" modified="2019-10-16" version="1">MSKTKVNVTIDESGDVDRLLQTMPDVLQHKQLPKALRAGAKPIIRDAKQRVSQPGYPGDKPGKEPLKNTIHAVIRKYEYTSIAVVGCTWPDGNHGWLVEFGHDITRTKGGPVFGHVPPYPFMRPAIDATRSEVAGSVLLVLQMGVREFNSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITY8</accession>
    <name>A0A518ITY8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_25440</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="46" mass="4804" checksum="D06ED5A98739C987" modified="2019-10-16" version="1">MPKTLRALGVDDGAIARTTDIDTSIATLRLPGPHDKTLNAISTLAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IU67</accession>
    <name>A0A518IU67_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_26270</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024524">
        <property type="entry name" value="DUF3800"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12686">
        <property type="entry name" value="DUF3800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="212" mass="24115" checksum="96FC526944898DFA" modified="2019-10-16" version="1">MLVFFDESGDTGMKLGAGSSRYFVVTGVLFLDRDEALRCDQAIDRFRQKSGASGREFKFAKMPDAFRLQFFQAVQSFEFLYSTFVLDKSLISGAGFHDSRSCYKDSTRLLFENMAPHLRDAIVVLDRCGNRDFVNQLKKYLKTHANAGERRAVKKVKTDDSHKNNLVQLADMVCGAVARCYSSSAGNRRQFRRLIEHNELEVRIWPTATDAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IU70</accession>
    <name>A0A518IU70_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">D-alanyl-D-alanine-carboxypeptidase/endopeptidase AmpH</fullName>
            <ecNumber evidence="3">3.4.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ampH</name>
        <name evidence="3" type="ORF">Mal33_26300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.4.-.-" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021816766" evidence="1">
        <location>
            <begin position="27"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-lactamase" evidence="2">
        <location>
            <begin position="35"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="361" mass="38737" checksum="8A3A3ADF6213FF65" modified="2019-10-16" version="1" precursor="true">MIGQNLFRIGMLLVLASAVVAAPAQADDDVAAIIQRLATPYIESKQAVGLSVGVLKGDQATTQHLGQTRTGGPAPDDDTIYEIASISKVFTGLLLADAVAREQLQLDQAAQELLPEGVTMPAGETRPIQLVDLATHRSGLPRLADNMPSLQTDNPYVDYTTTLAYEFLNSHRLRREPGAAHEYSNLGFALLGSVVADRAQLSYDQLLQQRIAEPLGMADTRVALTASMRDRLAKPHLTDGTETANWDFADMPGAGGIRSSLADMLRFAAANLKPESSKLEPAIEIAWQVHRDDSDQGPVMGLGWHVAGDGSTRWHNGQTGGYHSMLMINRRAGAAVVVLSNTASEKIDTLAVQLLQAVAQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IU91</accession>
    <name>A0A518IU91_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_26540</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022132604" evidence="2">
        <location>
            <begin position="23"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="49" mass="5009" checksum="7EBCE7BCB91D8900" modified="2019-10-16" version="1" precursor="true">MFSAIRLTLLTAVLCIPMIGCAPSTPSEEPTTETTAEPASKPQGSGTSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IV29</accession>
    <name>A0A518IV29_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Chemotaxis protein CheY</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">cheY_2</name>
        <name evidence="3" type="ORF">Mal33_29520</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="4"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="124" mass="13574" checksum="029F1AD5929467AB" modified="2019-10-16" version="1">MDQKVLLADDSGVMRKIILRALNAAGVTDVVEAADGAQAWTAFQTTQFDMVLTDWNMPMMTGLDLLKNIRQAGSTIPVIMITTESERGRVIEAIQAGVSDFLPKPFENELLQEKLVKHLSAIAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IV47</accession>
    <name>A0A518IV47_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_29580</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022118411" evidence="1">
        <location>
            <begin position="25"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="124" mass="14151" checksum="EF0993480BCCB44D" modified="2019-10-16" version="1" precursor="true">MNKHFTIALTMLAGIVLGTSTAEAVDIYGRTNVQAMNFAATRPWHSHYQYSNWGTPVAMIVPPTAHMQTNYSWGVSQNLSYPIHHQFNRNMPQPMGVPYGQFRPTPHWPSHTDQFGVHYIRGPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVB8</accession>
    <name>A0A518IVB8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_30290</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013321">
        <property type="entry name" value="Arc_rbn_hlx_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010985">
        <property type="entry name" value="Ribbon_hlx_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008651">
        <property type="entry name" value="Uncharacterised_HicB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05534">
        <property type="entry name" value="HicB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47598">
        <property type="entry name" value="SSF47598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="95" mass="10215" checksum="AEF9CA5484998813" modified="2019-10-16" version="1">MATLSLRMRDDLKAKAQQLASEQGVSLNSYINATLAATVAQAETLAMMGDKFDGVDRDRLRARVMKFMSATQSGPEPTPVEIERAIAGKSDVGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVE9</accession>
    <name>A0A518IVE9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Type I site-specific deoxyribonuclease</fullName>
            <ecNumber evidence="3">3.1.21.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">hsdR_3</name>
        <name evidence="12" type="ORF">Mal33_30630</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endonucleolytic cleavage of DNA to give random double-stranded fragments with terminal 5'-phosphates, ATP is simultaneously hydrolyzed.</text>
            <dbReference type="EC" id="3.1.21.3"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the HsdR family.</text>
    </comment>
    <dbReference type="EC" id="3.1.21.3" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="REBASE" id="355361">
        <property type="entry name" value="PbaMal33ORF30680P"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009035">
        <property type="term" value="F:type I site-specific deoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007409">
        <property type="entry name" value="Restrct_endonuc_type1_HsdR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040980">
        <property type="entry name" value="SWI2_SNF2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04313">
        <property type="entry name" value="HSDR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18766">
        <property type="entry name" value="SWI2_SNF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="8 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0680">Restriction system</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="11">
        <location>
            <begin position="306"/>
            <end position="541"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QDV57062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1080" mass="121925" checksum="F14869D14B50E790" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVH2</accession>
    <name>A0A518IVH2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transposase for transposon Tn5</fullName>
            <ecNumber evidence="7">3.1.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">tnpA_6</name>
        <name evidence="4" type="synonym">tnpA_3</name>
        <name evidence="5" type="synonym">tnpA_4</name>
        <name evidence="6" type="synonym">tnpA_5</name>
        <name evidence="8" type="synonym">tnpA_7</name>
        <name evidence="4" type="ORF">Mal33_01540</name>
        <name evidence="5" type="ORF">Mal33_21120</name>
        <name evidence="6" type="ORF">Mal33_24140</name>
        <name evidence="7" type="ORF">Mal33_30800</name>
        <name evidence="8" type="ORF">Mal33_35220</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.-.-" evidence="7"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.740.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038215">
        <property type="entry name" value="TN5-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003201">
        <property type="entry name" value="Transposase_Tn5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014737">
        <property type="entry name" value="Transposase_Tn5-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014735">
        <property type="entry name" value="Transposase_Tn5-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02281">
        <property type="entry name" value="Dimer_Tnp_Tn5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14706">
        <property type="entry name" value="Tnp_DNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tnp_DNA_bind" evidence="3">
        <location>
            <begin position="8"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="domain" description="Dimer_Tnp_Tn5" evidence="2">
        <location>
            <begin position="378"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="250"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV54205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV56133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV56424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV57079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV57512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="474" mass="53338" checksum="DA6AF6371D944488" modified="2019-10-16" version="1">MQPTSIAYEFQDIQLGDKRLNDRAEALLASLAANPSASINEACSGWDETKAAYRLFDNPNVDPEAILGAHAEKTLQRIKAQDTVCIAQDTTELDYTAHPPEGVRNLDRLGRRGLYDHSHIAFTPEKLCLGVVGVKFYDRDKETLGTSKKREGQPLHTGEGQRWLDGYRKACEIAGKCPETQIVSLADREGDIYDIFVEADQHETPAQFVIRSQRKRSLPEKDPDGGPAAYKKMRAEIASAQPVAYREVQLPQTPERTKGSGNKQHPGREARTAKLEIRAKRMTLRAPHNKQSSMPPVEISVVWVSEIDGPGDGTEVDWLLLSSLPVDTIAQTLRIVDLYVARWPIEVFFRVFKTGCRVEEIQLEARDRLIRALMFYKVIAWRIMFVTFLGRECPELPCDVVFSEAEWKSVWKVVEKTAPPKQAPELSQFIPVLATLGGYNHREGDGPPGAEVIWRGTRRMLDFALCWQAFGPDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVP4</accession>
    <name>A0A518IVP4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">3-dehydroquinate synthase</fullName>
            <shortName evidence="8">DHQS</shortName>
            <ecNumber evidence="8">4.2.3.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">aroB_2</name>
        <name evidence="8" type="synonym">aroB</name>
        <name evidence="10" type="ORF">Mal33_31590</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate = 3-dehydroquinate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:21968"/>
            <dbReference type="ChEBI" id="CHEBI:32364"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58394"/>
            <dbReference type="EC" id="4.2.3.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <cofactor evidence="8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="8">Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="8">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 2/7.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.3.4" evidence="8"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00085"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003856">
        <property type="term" value="F:3-dehydroquinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00110">
        <property type="entry name" value="DHQ_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016037">
        <property type="entry name" value="DHQ_synth_AroB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030963">
        <property type="entry name" value="DHQ_synth_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030960">
        <property type="entry name" value="DHQS/DOIS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01761">
        <property type="entry name" value="DHQ_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001455">
        <property type="entry name" value="DHQ_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01357">
        <property type="entry name" value="aroB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="7 8" id="KW-0170">Cobalt</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8 10" id="KW-0456">Lyase</keyword>
    <keyword evidence="2 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 8" id="KW-0520">NAD</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="DHQ_synthase" evidence="9">
        <location>
            <begin position="74"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="78"/>
            <end position="83"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="112"/>
            <end position="116"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="136"/>
            <end position="137"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="149"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="176"/>
            <end position="179"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="191"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="255"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="272"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV57158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="368" mass="39859" checksum="F287EC3C2549E69F" modified="2019-10-16" version="1">MVLPNVPDRLEVPLPDAPYPILIGSDWLSDLVSPIADRMPDLSHAIIIHDAAVAQPWAATIQQALQDRYRTDMISVPSGEPSKCVEQLQRLWIGLLEAKTDRKSAIIAVGGGVVGDLAGMVAATFMRGIRFVQVPTTLLAQVDSSVGGKTGINLPGAKNMVGSFWQPRLVAIDIATLGTLAPREFISGLAEVAKYGVICDAEFFAWLQQNHEAIHARDAAALKHAIRTSCQAKADVVLADERETTGRRATLNYGHTFGHAIEALAGYGHFLHGEAIAIGMQIAADLARRMGRVDDAFCEQQTELFTSLQLPITWSEADPDAMLGAMFSDKKTEHGKLRFILPTKIGHVELVDDVPEDLVRQAITACSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVV5</accession>
    <name>A0A518IVV5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_32250</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MYG1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003226">
        <property type="entry name" value="Met-dep_prot_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03690">
        <property type="entry name" value="UPF0160"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="292" mass="32725" checksum="0E9A96250F8A1F35" modified="2019-10-16" version="1">MAIQLIVTHPGGAHKDDFLACSLLAHLHGVPIQRREPTEEDLADSTICVVDVGEVHDPEQNNFDHHQFPRDAPPLCALSLVLQNMGLYDDALSFCAWLRPAEWLDTLGPNEAAKLMGIPRAALGALNSPLDITLLNRFASQTELRPDSPVYQVMCMVGEDIVNYLQSLRQRLDYLKTHAQYWTIESDGESIQALFLEKSDTLANDPSFGVYAFIESEGKQDAIQAMVTPDRRGEGYGLSRYNDSQRLDYSQIETHEEVRFAHKRGFVAKVTTNDPTRLKELLKDAIVKSEAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVW1</accession>
    <name>A0A518IVW1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF1080 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_32190</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010496">
        <property type="entry name" value="3-keto-disaccharide_hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06439">
        <property type="entry name" value="DUF1080"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021730483" description="DUF1080 domain-containing protein" evidence="1">
        <location>
            <begin position="28"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1080" evidence="2">
        <location>
            <begin position="45"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="259" mass="28508" checksum="DE58A610C05BCAB5" modified="2019-10-16" version="1" precursor="true">MRMTSRINVLGMLPCMIAGLLVSLAFEADLGAEPPAADATPEIPQWVDLFNGRDLSGWANVNTEPDTWSVKDGLLVCSGKPIGVMRSEKQYENFILHIEWRHMKAGGNSGVFAWSEGFVPEGSRLPKGMEIQMLELDWVNQHPLKNGEPNHIGYISGELFGAGGLTATPDNPRGRRSMSVELRCKGVGQWNVYDVVCVDGTVKLAINGKFVNSIRDSSVRKGYLCLESEGSEIHFRNIRILELPPGITTPEQTAKVIEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IW48</accession>
    <name>A0A518IW48_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">WD domain, G-beta repeat</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_33130</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037783">
        <property type="entry name" value="Taf5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_repeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19879">
        <property type="entry name" value="PTHR19879"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="361" mass="39391" checksum="F2D83E763895BD56" modified="2019-10-16" version="1">MKSITLKEKHRHKLPMGILSMALLPDGVGLVAGCMDGVYLTSIDKSREPKLLYSHGNYVSSVVSLGGDTIVSAGYDGTARWFDLAEQKLTDSVKLHDFWSWDMTASPDGKHLASVTGQYLAGGYKYEPQEESEPSIRVVDVASKQIVHSLPHVPSVQSVAISPDNQFVAAGNLMGEVRIYRIADGELVSQWTTSDFTSWGIIKSHCYLGGIFAMQFSRDGKHLLLAGMGPMRDPMAGNGKQLWQKWDWQAAEPKMIDQTHEGDAGEGLMETLAVHPSGEMFAMGGRLRGGDWNVALFDMQTGDRMAILKLGFRATEATFTPDGKHLVIVGTQGQPSKPKPKGDGFPDFGRVEVFAIESEAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IW49</accession>
    <name>A0A518IW49_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Helix-turn-helix domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_33170</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041657">
        <property type="entry name" value="HTH_17"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12728">
        <property type="entry name" value="HTH_17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="484"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="domain" description="HTH_17" evidence="3">
        <location>
            <begin position="8"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="227"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="355"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="290"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="322"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="355"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV57313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="538" mass="54363" checksum="77CC0FC41F6A2BD2" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IW81</accession>
    <name>A0A518IW81_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_33590</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="76" mass="8630" checksum="DD24E5FFF607F690" modified="2019-10-16" version="1">MQRSNLRMQWAPSSHYHLSGSLREPGYWTAGLESAQKNEKRRSGSGLIRAESADPSHSFGIIQKLRSVYLIRTTIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWW9</accession>
    <name>A0A518IWW9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Uridylate kinase</fullName>
            <shortName evidence="6">UK</shortName>
            <ecNumber evidence="6">2.7.4.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Uridine monophosphate kinase</fullName>
            <shortName evidence="6">UMP kinase</shortName>
            <shortName evidence="6">UMPK</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 8" type="primary">pyrH</name>
        <name evidence="8" type="ORF">Mal33_35920</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the reversible phosphorylation of UMP to UDP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>ATP + UMP = ADP + UDP</text>
            <dbReference type="Rhea" id="RHEA:24400"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.22"/>
        </reaction>
    </comment>
    <comment type="activity regulation">
        <text evidence="6">Inhibited by UTP.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 6">Pyrimidine metabolism; CTP biosynthesis via de novo pathway; UDP from UMP (UMPK route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the UMP kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.22" evidence="6"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00159">
        <property type="reaction ID" value="UER00275"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033862">
        <property type="term" value="F:UMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044210">
        <property type="term" value="P:'de novo' CTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04254">
        <property type="entry name" value="AAK_UMPK-PyrH-Ec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01220_B">
        <property type="entry name" value="PyrH_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011817">
        <property type="entry name" value="Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015963">
        <property type="entry name" value="Uridylate_kinase_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005650">
        <property type="entry name" value="Uridylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="SSF53633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02075">
        <property type="entry name" value="pyrH_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 6" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AA_kinase" evidence="7">
        <location>
            <begin position="13"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="18"/>
            <end position="21"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>UMP</name>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="143"/>
            <end position="150"/>
        </location>
        <ligand>
            <name>UMP</name>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV57581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="249" mass="27125" checksum="807FF5181E6174A9" modified="2019-10-16" version="1">MTTEAANSELRYKRVVLKLSGESLAHSGERGISMEEVGDISAQIKQATQSGCQVAVVIGGGNILRGAQFSGRSSLINESTAHYMGMLATVMNSLSLQDALEQIGCPTRVMSSIRMDGVCETFVRRRAIRHMEKGRVIILAAGIGRPFVTTDTAAAQRALELEADVVLKATRVDGVYSEDPEKNPHALLYDRLSFKDVIERNLRVMDATAIAMCREHSLPILVFNFKKDGNIVRAVSGENIGTRIEESVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWY1</accession>
    <name>A0A518IWY1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative deoxyhypusine synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_36130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the deoxyhypusine synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008612">
        <property type="term" value="P:peptidyl-lysine modification to peptidyl-hypusine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002773">
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    </dbReference>
    <dbReference type="InterPro" id="IPR036982">
        <property type="entry name" value="Deoxyhypusine_synthase_sf"/>
    </dbReference>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR11703">
        <property type="entry name" value="PTHR11703"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="322" mass="35916" checksum="ABF469BF0470AA1D" modified="2019-10-16" version="1">MSNISKFMDDHFRHFNARETVAAAQAYKDQLASGNKMMVSLAGAMSTGEIGRSLAEMIRQDKVHAISCTAANLEEDIFNLMAHDEYKIVPNWRALSTEDEVELLNQGFNRVTDTCIPETVMRNIEGRMLTLWKDAADNDRPRFPYEFMYELLDDPTLEPLFQIPKENSWMLAAKEKGLPIFVPGIEDSTLGNIFAARVTQGIVSSHRAMRSGTEQMSKLIGWYQEQTNSGAEIGFFQVGGGIAGDFAICVVPTMIQDLKLDIPLWSYFCQISDAVTSYGGYSGAVPNEKITWCKLSGEAPKFMIQSDASIVAPLMFAYILGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IX21</accession>
    <name>A0A518IX21_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphoserine phosphatase RsbU</fullName>
            <ecNumber evidence="2">3.1.3.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rsbU_2</name>
        <name evidence="2" type="ORF">Mal33_36520</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.3.3" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036424">
        <property type="term" value="F:L-phosphoserine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00060">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07228">
        <property type="entry name" value="SpoIIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00331">
        <property type="entry name" value="PP2C_SIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SSF49879"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="SSF81606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="1">
        <location>
            <begin position="23"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="567" mass="61511" checksum="764A5A26A99CBED9" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IX71</accession>
    <name>A0A518IX71_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glucosamine-6-phosphate deaminase 1</fullName>
            <ecNumber evidence="2">3.5.99.6</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">nagB_2</name>
        <name evidence="2" type="ORF">Mal33_36960</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.5.99.6" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004342">
        <property type="term" value="F:glucosamine-6-phosphate deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006044">
        <property type="term" value="P:N-acetylglucosamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01399">
        <property type="entry name" value="GlcN6P_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006148">
        <property type="entry name" value="Glc/Gal-6P_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003737">
        <property type="entry name" value="GlcNAc_PI_deacetylase-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004547">
        <property type="entry name" value="Glucosamine6P_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018321">
        <property type="entry name" value="Glucosamine6P_isomerase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024078">
        <property type="entry name" value="LmbE-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01182">
        <property type="entry name" value="Glucosamine_iso"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02585">
        <property type="entry name" value="PIG-L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102588">
        <property type="entry name" value="SSF102588"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01161">
        <property type="entry name" value="GLC_GALNAC_ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucosamine_iso" evidence="1">
        <location>
            <begin position="32"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="633" mass="70382" checksum="DD11F1F09626EB89" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IX83</accession>
    <name>A0A518IX83_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_37150</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="76" mass="8760" checksum="BB7D68068065C08B" modified="2019-10-16" version="1">MRTDLASCKDRSKELVRSKLVLVRSKLVLVRSKLVLVRSKLVLVRSKLVLVRSKLELVRSKLVLFRSKLVLERSTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXD1</accession>
    <name>A0A518IXD1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_37520</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="308" mass="34252" checksum="D7476D167A43613B" modified="2019-10-16" version="1">MRRSFVSLMTAMTFLVIAVTGVLAFVQPFSVTIVGLHALMGFLFIGVVGFHLANNLQPLKRYLRSKWMWINLAVTAALTTAIALQPQPVKALLGLSGNLGPALDRFELHDEGLTYQYTPAPHYKLTLSVRMGDAFDPADPPEFAIWIENSSFYHIKTLHRPEAADNEASLPYWSFKVKEYEKAKLAAAAGVDVDAVSGATKNSSFDPADYMLPVDPEEPMPYRILVEINQPGDANEAVDDQPSLIYSVEVDNSDPNAFQLLDLIGYPQLEEDEQPPQWAIYYVDQRFDSALELIDSALLTIDRDKPAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXI6</accession>
    <name>A0A518IXI6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">1-deoxy-D-xylulose 5-phosphate reductoisomerase</fullName>
            <shortName evidence="7">DXP reductoisomerase</shortName>
            <ecNumber evidence="7">1.1.1.267</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">1-deoxyxylulose-5-phosphate reductoisomerase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">2-C-methyl-D-erythritol 4-phosphate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 11" type="primary">dxr</name>
        <name evidence="11" type="ORF">Mal33_38180</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>2-C-methyl-D-erythritol 4-phosphate + NADP(+) = 1-deoxy-D-xylulose 5-phosphate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:13717"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57792"/>
            <dbReference type="ChEBI" id="CHEBI:58262"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.267"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1 7">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 1/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the DXR family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.267" evidence="7"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00056">
        <property type="reaction ID" value="UER00092"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030604">
        <property type="term" value="F:1-deoxy-D-xylulose-5-phosphate reductoisomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070402">
        <property type="term" value="F:NADPH binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019288">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00183">
        <property type="entry name" value="DXP_reductoisom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003821">
        <property type="entry name" value="DXP_reductoisomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013644">
        <property type="entry name" value="DXP_reductoisomerase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013512">
        <property type="entry name" value="DXP_reductoisomerase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026877">
        <property type="entry name" value="DXPR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036169">
        <property type="entry name" value="DXPR_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30525">
        <property type="entry name" value="PTHR30525"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08436">
        <property type="entry name" value="DXP_redisom_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02670">
        <property type="entry name" value="DXP_reductoisom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13288">
        <property type="entry name" value="DXPR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006205">
        <property type="entry name" value="Dxp_reductismrs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69055">
        <property type="entry name" value="SSF69055"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00243">
        <property type="entry name" value="Dxr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6 7" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 7" id="KW-0521">NADP</keyword>
    <keyword evidence="5 7 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DXP_reductoisom" evidence="8">
        <location>
            <begin position="8"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="DXP_redisom_C" evidence="9">
        <location>
            <begin position="144"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="DXPR_C" evidence="10">
        <location>
            <begin position="265"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="11"/>
            <end position="40"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="148"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="150"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="203"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QDV57803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="392" mass="42196" checksum="F375DF3395D726E5" modified="2019-10-16" version="1">MAVSTRNVAILGATGSIGRATLDVVASLGDSWNVWGVSGHSRSEELSQIARQTTPEMAVLTGDADPQSLDLPGKTRLLTGADALVELATAPEVDVVMAAIVGRAGLESTLAALQAGKRVALANKEALVVGGPLVHAMRQNGGELLPVDSEHSAIFQCLTSGGGSLAEGKKSVRKLILTSSGGPFRTWTTAQMRDASIEDALKHPTWNMGRKISIDSATMMNKGLEVIEARWLFDIPADRIEVVVHPQSIIHSMVEFEDGSILAQLSPPDMRLPIQYALTYPERLPCIAPPLDRSRAWDLSLEPVDHDRFPALNLAFEVARVGGTAGAVVNAANEQAVALFLDGQIRFTDIVPACRMALENHQHESEPSLQRLLQLDRWARAEVQRWSCGMQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXN4</accession>
    <name>A0A518IXN4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Thioredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">trxA_5</name>
        <name evidence="6" type="ORF">Mal33_38690</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016209">
        <property type="term" value="F:antioxidant activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022149255" evidence="4">
        <location>
            <begin position="20"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="5">
        <location>
            <begin position="181"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="73"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="125"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV57854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="505" mass="54174" checksum="F21760008A9642FA" modified="2019-10-16" version="1" precursor="true">MLTLRPRHCRLLMVLPFLAVGCGGPSRSALEKASYETDGLASSSKLAEIAVPDVAVGEMTPGQIDSYDVQLAPRESQRPASGPKSPAPAASVRPASSPAPAALSPAAPAATVALKPAALNVPPAETQAPATIEPPLAIKPPAATKPAPAAKPASVAKPTVAVKPPAAEPPSFAAPANTGSLTIGDRAPELEIDTWFKGPEVGSFEDSKVYVVEFWATWCGPCKVNMPHLSQLQQQLGDQVQFIGVSDEPAAKIASFFEAEASPGKTWGDVLQYTIAADSNKSTKLRYMQAAGERGIPCAFIVGRDGVVQWIGHPAQIDRPLAAILEGDWDVAAARTSRDKAKRYELAFGALRSRMGGWIKDKDYASAIAALDAMATEFPERNEPLMIKLEVLREAKMFSETYPVIDKLVQRQWDDPNMLAQLAWLIAAETKGDDRDLDLALKAAVRSVELTNEKAPIALDTVARVHFERGDVAEAIEWQVKATKMPSKFKEDMLKTLEIYQQAAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXW5</accession>
    <name>A0A518IXW5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_39400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009297">
        <property type="entry name" value="DUF952"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34129">
        <property type="entry name" value="PTHR34129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06108">
        <property type="entry name" value="DUF952"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="117" mass="13014" checksum="0CCB6501AD76F8E3" modified="2019-10-16" version="1">MNDPHPLIYKILTPAQWQAFQNDGQFLGAPIDLADGFIHFSAEHQVEETVAKHFAGQGDLILAEVATDSLGEALRWEVSRGGDLFPHLYAPLPLKAVARQTVLQQLESGSHRFPVQW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IY02</accession>
    <name>A0A518IY02_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sialidase</fullName>
            <ecNumber evidence="3">3.2.1.18</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">nedA_2</name>
        <name evidence="3" type="ORF">Mal33_39780</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.2.1.18" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052794">
        <property type="term" value="F:exo-alpha-(2-&gt;3)-sialidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052795">
        <property type="term" value="F:exo-alpha-(2-&gt;6)-sialidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052796">
        <property type="term" value="F:exo-alpha-(2-&gt;8)-sialidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008152">
        <property type="term" value="P:metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011040">
        <property type="entry name" value="Sialidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026856">
        <property type="entry name" value="Sialidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036278">
        <property type="entry name" value="Sialidase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10628">
        <property type="entry name" value="PTHR10628"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13088">
        <property type="entry name" value="BNR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50939">
        <property type="entry name" value="SSF50939"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022097618" evidence="1">
        <location>
            <begin position="25"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="domain" description="Sialidase" evidence="2">
        <location>
            <begin position="71"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="369" mass="41105" checksum="327DEC56CC4198E9" modified="2019-10-16" version="1" precursor="true">MNQRTNIAFATLLVIAASISSVVAAEAIEDIHIVPKPEKLRGYRGINGDLIQRKDGSLLFCYTEPGDGGGIVSKTSTDQGSTWSEPKVIVAQPPSSGPGRYNHPSLLQLDNGDLLISYNYTTHPAKPYYAMTLYRRSADQGETWSEQLPMTPYAGYTLVHNDKLLSLKDGRVIAVAVTKKYMPSSHDHNGYVGLTFYSDDQGYSWHPSKNEVDLYDSKKIEVQEPDAVELKDGRLLMFARSYSGHPVKAYSEDRGETWSKGELIRELKMPYAGLPTVRRIPSTGDLLFIWISGKSKSESGLPLRSVLSTAISQDEGETFVHQRNLVDDPTNDLGYQCIEFLEDGTALIVYHSNDGLHMSRLNVDWFYGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IY65</accession>
    <name>A0A518IY65_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_40450</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="170" mass="18452" checksum="9B5F1748CB4CC587" modified="2019-10-16" version="1">MNLNKLDEFLAAQIEARTPSEGIDAMCKHAPANRLVWWGCLSAWSIWRPTPPPHEDAALAVAARWVFQPGDDLRRAAALQAKADTAGLCKWLLQAVQYSGGHLKIDDGGIALPTPDVSGAYTKGFIHNLLAVNPPVERATASQNFLQLARQAITRPMPTAEPTQPTPQLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYC8</accession>
    <name>A0A518IYC8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_41100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="102" mass="11236" checksum="B54C0698372671CC" modified="2019-10-16" version="1">MACWNRAFQPPRGAKYQPQFGLYSSRPLRFSHRLRGAIQAAVAGQISRGHNPPLHRWSLAAGMMHCIKLCKLQARRSETEGVHLSRGAVLTLCGAVSNIMPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYG2</accession>
    <name>A0A518IYG2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">2-dehydro-3-deoxygluconokinase</fullName>
            <ecNumber evidence="2">2.7.1.45</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">kdgK_2</name>
        <name evidence="2" type="ORF">Mal33_41370</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.1.45" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008673">
        <property type="term" value="F:2-dehydro-3-deoxygluconokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PfkB" evidence="1">
        <location>
            <begin position="1"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="363" mass="38831" checksum="F652EA61F8DE34EF" modified="2019-10-16" version="1">MSKVVTFGEIMGRLAPPGFLRLPQAMPGSLDVTFAGAEANVAASLSILGLDAHFVTALPNNPIADACVNSLRSIGIDTSSILRSDIGRLGLYFLETGANQRPSRVIYDRDGSTIGQTPADAYDWDKIFVGADWFHVTGITPAVSQVAAEATLHAAKAAKQRGLTVSCDLNFRGKLWRWDSSASPHELAGRAMRQLLPLVDVLIANEEDCGDVLQIRAAETDVASGKLSAERYPEVARRVVQEFPNLRYVATTLRESISASHNNWGAMLYDAAAESASFAPRSDGEYEPYSIRNIVDRVGGGDSFAAGLIFGLLNDDYPTPQAALQFAVAASCLAHSIIGDLNFSSREEIDALAKGSASGRVVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYT6</accession>
    <name>A0A518IYT6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_42700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011453">
        <property type="entry name" value="DUF1559"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07596">
        <property type="entry name" value="SBP_bac_10"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021735433" evidence="1">
        <location>
            <begin position="25"/>
            <end position="539"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="539" mass="58879" checksum="D71D591A6208A48F" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYW4</accession>
    <name>A0A518IYW4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_42920</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022068711" evidence="2">
        <location>
            <begin position="20"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="182"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="230"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="493" mass="53703" checksum="2D55D03815254301" modified="2019-10-16" version="1" precursor="true">MSLAAAMPLAALETLPAQAQATWDTPRAAQTQAAPRTTTASRFDASFSNATSDTSVVARRPSQPQPSSSQPNKLQWRSSDRVAPRTFASGSKTNLSADNGPVMRVAYQQEGTVPDDLFGEQPGSNRQAPGSDADPFDNDVFGNPFQAPPAATPAPVSPPAGGNAPDALRMPELSQPNEAAPELPPAVAPAPQPEQPSPLLPPTNDQRDNLDESKLDMLDNNPFKRGPAGETDSPSDRQEDSQPTEPESEPDFVPRRGFGITPPQPRTNLSCEDLRQEVASRTISRISLDISPAYRPDVLDDKKFAELRSDFEKNQKPRDWRGVDGSLLGRGTLYDLSYQDVVLHTESGGTQKIDISRLSEADLAFLSKEWGLPRVCRIAQVAYQPRNWVPSTMTWKASNLCHNPLYFEEVQLERYGHSAGPLKQPLISTAHFFVNIAVLPYKMGIHAPDECQYALGYYRPGNCAPYMLPPIPLSLRGTLSQAAVVAGGFWLIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYW8</accession>
    <name>A0A518IYW8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytochrome c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Mal33_43040</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002327">
        <property type="entry name" value="Cyt_c_1A/1B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013427">
        <property type="entry name" value="Haem-bd_dom_put"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11961">
        <property type="entry name" value="PTHR11961"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00034">
        <property type="entry name" value="Cytochrom_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02603">
        <property type="entry name" value="CxxCH_TIGR02603"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="3 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Cytochrome c" evidence="7">
        <location>
            <begin position="1036"/>
            <end position="1169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="77"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="702"/>
            <end position="727"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV58286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1182" mass="129087" checksum="403C48016064B933" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYX3</accession>
    <name>A0A518IYX3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Biopolymer transport protein ExbD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Mal33_42950</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the ExbD/TolR family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003400">
        <property type="entry name" value="ExbD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30558">
        <property type="entry name" value="PTHR30558"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02472">
        <property type="entry name" value="ExbD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV58277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="124" mass="13720" checksum="382E54257A659634" modified="2019-10-16" version="1">MTPMIDVVFLLIIFFLVSSHLARQESRIPLDLPVADASVDQPPPSDVFTINVFPDGAWQVSGTEVDRAMLDRLLQSHRAEHGEDAAVRIRTDRSVAYGQVEPLLRAASAAGLWNASFAVYQETR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ13</accession>
    <name>A0A518IZ13_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Outer membrane biogenesis protein BamB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_43390</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002372">
        <property type="entry name" value="PQQ_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13360">
        <property type="entry name" value="PQQ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021764618" evidence="1">
        <location>
            <begin position="22"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="429" mass="46341" checksum="773CDE10321BC2D3" modified="2019-10-16" version="1" precursor="true">MFDLLARCSLCLLIVIPGCDAADPVPVADSVGAQALSTASWPCWMGPRYDGISTEANWSADWPDEGLPIVWTQQLGIGFSSISIADGRLFSMGHVDGEEFVYCLDAATGKTLWTHRYACELVDNLYEGGPGSTPTIDGDLVYTLGKQGQLFCFRAADGEIVWQKDLQVDLEIPMPEWGFNSSARVVDDAVVFEAGRVVSYHKLTGEKNWQSEPHRAGYGSVARFAGDRSGLLATLDCDAVRISDATDGSEVALFPWKSPFGTNSTTPILAGDKIFVSTGYQVGCGLFQLNEDGLDLIYENRSMRNHFNNCILYDGYLYGIDGNSNLGRVVHLVCMNLETGEVAWRERGFGCGSLMIADGKLVILADDGRLVLAEATPEEYRQLASSPFLEGRCWTVPVLAGGHIYGRNAAGKIVCARLPAKSAATSAGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ21</accession>
    <name>A0A518IZ21_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Planctomycete cytochrome C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_43460</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011429">
        <property type="entry name" value="Cyt_c_Planctomycete-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011444">
        <property type="entry name" value="DUF1549"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022655">
        <property type="entry name" value="DUF1553"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07635">
        <property type="entry name" value="PSCyt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07583">
        <property type="entry name" value="PSCyt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07587">
        <property type="entry name" value="PSD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PSCyt1" evidence="3">
        <location>
            <begin position="47"/>
            <end position="102"/>
        </location>
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    <feature type="domain" description="PSCyt2" evidence="1">
        <location>
            <begin position="168"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="domain" description="PSD1" evidence="2">
        <location>
            <begin position="570"/>
            <end position="832"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV58328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="880" mass="98704" checksum="A5573B97DB9EAEB1" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZJ4</accession>
    <name>A0A518IZJ4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_45430</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="23"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="55"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="151"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1059"/>
            <end position="1093"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1122"/>
            <end position="1188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1288"/>
            <end position="1313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1390"/>
            <end position="1541"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1561"/>
            <end position="1932"/>
        </location>
    </feature>
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        <location>
            <begin position="1059"/>
            <end position="1081"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1130"/>
            <end position="1144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1166"/>
            <end position="1180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1404"/>
            <end position="1447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1456"/>
            <end position="1484"/>
        </location>
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    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1485"/>
            <end position="1499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1501"/>
            <end position="1535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1595"/>
            <end position="1613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1707"/>
            <end position="1721"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1779"/>
            <end position="1804"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1828"/>
            <end position="1881"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1953" mass="214234" checksum="25DB95D8F8A807AE" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZN0</accession>
    <name>A0A518IZN0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_45670</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="464" mass="50672" checksum="362A9FFE6D814F22" modified="2019-10-16" version="1">MSDSTATVPAFHHAAFHGRVGIALNDITPPVGIYSRNWGAAAHDVSDSIHRSLTLTATTIASLSGESPLVLIDADLGWWRTPELFPRFQQRLLEEFSLDSSQLIFALTHTHAGPPLLESTDPLPGMELTKPWLDSLLETAVTTVRQAFADASEATLEWRTGHCGLATTRDLPDPDSESDRFLCGFDPEGQADGTLLLGRVTDAQGNLRATIVNYACHPTTLAWENTAISPDYIGAMRETIQQATGAPAVFLLGACGDQAPRYQYVGDTAVADGHGRELGYAALSTLAGMEPAGTQLAFEGAVTSGAPLAKWRHQPRKASEKIASVESSVDLPLKDWPSAAELEAQRIACTDRTLQERLLRRRDIRLRLGDGTTYPLPLNIWRMGDAVLVGSCCEAYSMLQRELRKRFPNNAIICMNLINGTIGYLPPADLYDKDVYAVWQTPFDRGCLEATLETLTQEIDDILR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZY5</accession>
    <name>A0A518IZY5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SMP-30/Gluconolaconase/LRE-like region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_46810</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013658">
        <property type="entry name" value="SGL"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08450">
        <property type="entry name" value="SGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SGL" evidence="1">
        <location>
            <begin position="21"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="319" mass="34702" checksum="2E331A39A8E2499B" modified="2019-10-16" version="1">MTQRITATPFYRPSDAALRFLPEGPYPNGPSKMSWVAIQHGADATQGSLNVFDFESGNNRSHVLPGRPGFAFPCDDGHSFVAGCERTLGIFHPSEMTWSPFCENIDEAVEGTVINDGLVWENNLIFGTKDLEFKTPKAGLYLWRGSDRSLIQLRNDQVCSNGKAIVEVDGKTFLIDIDSPTRKIVRYPIDIAAGTLGDAEVVVDLTADPGVPDGAIVTPDGRSVIVSIYNPNPAPHGETRQYDMKTGELVTVWETPGSPQNTCPNLIEHDGKVHLVITTAVEHMPEDRQADAPQAGSLFIAPTEFESVGNNPRFPLGSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J003</accession>
    <name>A0A518J003_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ribosomal protein S12 methylthiotransferase RimO</fullName>
            <shortName evidence="7">S12 MTTase</shortName>
            <shortName evidence="7">S12 methylthiotransferase</shortName>
            <ecNumber evidence="7">2.8.4.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Ribosome maturation factor RimO</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">rimO_2</name>
        <name evidence="7" type="synonym">rimO</name>
        <name evidence="10" type="ORF">Mal33_46920</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>[sulfur carrier]-SH + AH2 + L-aspartate(89)-[ribosomal protein uS12]-hydrogen + 2 S-adenosyl-L-methionine = 3-methylsulfanyl-L-aspartate(89)-[ribosomal protein uS12]-hydrogen + 5'-deoxyadenosine + [sulfur carrier]-H + A + 2 H(+) + L-methionine + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:37087"/>
            <dbReference type="Rhea" id="RHEA-COMP:10460"/>
            <dbReference type="Rhea" id="RHEA-COMP:10461"/>
            <dbReference type="Rhea" id="RHEA-COMP:14737"/>
            <dbReference type="Rhea" id="RHEA-COMP:14739"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:29917"/>
            <dbReference type="ChEBI" id="CHEBI:29961"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:64428"/>
            <dbReference type="ChEBI" id="CHEBI:73599"/>
            <dbReference type="EC" id="2.8.4.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="7">Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the methylthiotransferase family. RimO subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.8.4.4" evidence="7"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0103039">
        <property type="term" value="F:protein methylthiotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018339">
        <property type="term" value="P:peptidyl-L-beta-methylthioaspartic acid biosynthetic process from peptidyl-aspartic acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01865">
        <property type="entry name" value="MTTase_RimO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005839">
        <property type="entry name" value="Methylthiotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020612">
        <property type="entry name" value="Methylthiotransferase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013848">
        <property type="entry name" value="Methylthiotransferase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038135">
        <property type="entry name" value="Methylthiotransferase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005840">
        <property type="entry name" value="Ribosomal_S12_MeSTrfase_RimO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041582">
        <property type="entry name" value="RimO_TRAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023404">
        <property type="entry name" value="rSAM_horseshoe"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43837">
        <property type="entry name" value="PTHR43837"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18693">
        <property type="entry name" value="TRAM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00919">
        <property type="entry name" value="UPF0004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00274">
        <property type="entry name" value="ribosomal_protein_S12_methylth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00089">
        <property type="entry name" value="TIGR00089"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01125">
        <property type="entry name" value="TIGR01125"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51449">
        <property type="entry name" value="MTTASE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01278">
        <property type="entry name" value="MTTASE_RADICAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 7" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7" id="KW-0408">Iron</keyword>
    <keyword evidence="6 7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="10" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 7 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MTTase N-terminal" evidence="8">
        <location>
            <begin position="26"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="Radical SAM core" evidence="9">
        <location>
            <begin position="167"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="188"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV58668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="473" mass="52918" checksum="770F8DCC6B9846BC" modified="2019-10-16" version="1">MQLPIISAPNNAEPQAAPLADGDARGSYAVISLGCPKNTVDTEQMLGQLHEFGYRLVDNPDGADFVVVNTCGFIDSARQESMGAIDEMLDLKQQGKLRGVIVTGCLAERQRDQLMAARPEIDGMLGVFGRDDIVDVANRFVDGIAEQRTVFRPAPIQALPDNRRLGITPQHFAYLKISEGCDRLCTFCAIPKMRGKHASKPIEQVVAEARRMAESGVRELNVVAQDTTYYGLDLYGQTRLNELLQQLDAIDGLDWIRLMYFYPMYIDDQLLDTIASAKRIVPYIDMPLQHASDSMLRRMSRRVNRADTEVLLKKMRSRIDNLVMRTTFITGFPGETEQDVDQLYEFIETHQFERLGIFTYSLEPDTPAAKLPNPVPADVAEARRARLMQLQQEMAFDWNQQRIGTQADVLIDRPLPDQPGVWIGRTAADAPDIDGLVFVSEQDSPLDQGLMVRSEIVASQGYDLVAVPTEAPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J014</accession>
    <name>A0A518J014_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_47100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="entry name" value="BBP7"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07585">
        <property type="entry name" value="BBP7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022214646" evidence="2">
        <location>
            <begin position="38"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="495" mass="53200" checksum="2AE4F650E9AF97AE" modified="2019-10-16" version="1" precursor="true">MIMPMANIQTSSPRNLAFASLTWVMCVAILFSAAATAQTRQREVTRGTYNPPVLESGTAAPTKVLSSPAPNAGSSRAKVRPEPQPEVVRQVDYEVIELSEGPAAFEMGSGYCDSAGYCDSMGGGCGCGSPACGGCGPAACNPCFGYGMPCQRFFGSLEYSMYWRRGQTLPPLITTSPAGTATDVAGVLGQTSTTTLVGGLNRGEMTSGGRAQLGLWMDDFQCRSILVRFWAIGDETFNYTADQSTAAFVAVPFNNAALNNQADAFLIVEPGQATGSVNVQTRSEAYGGDALLRQKWRTGLGGRVDAFWGYQTARINEQLTLSIDSEGLDGGTRPGQRLQITDSFDAKNEFHGATFGFDSFYREGPWSWTMLTKIGFGSMHREAAIRGNTIRSSGGLEFPSSEGFFARNSNIGDTSSSKFSVAPEFDLKLGYTVRPGLDMTIGYSFQLFTNVVQPSGIFDTSTTDLATVPTNHPSVQFEDTSYWIQALNFGLAWNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0C9</accession>
    <name>A0A518J0C9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ribonuclease Y</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rny_2</name>
        <name evidence="4" type="ORF">Mal33_48190</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006675">
        <property type="entry name" value="HDIG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011624">
        <property type="entry name" value="Metal-dep_PHydrolase_7TM_extra"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011621">
        <property type="entry name" value="Metal-dep_PHydrolase_7TM_intra"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07698">
        <property type="entry name" value="7TM-7TMR_HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07697">
        <property type="entry name" value="7TMR-HDED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00277">
        <property type="entry name" value="HDIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="337"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="370"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="399"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="437"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="461"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="516"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="domain" description="HDc" evidence="3">
        <location>
            <begin position="565"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="676"/>
            <end position="696"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV58794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="783" mass="85895" checksum="67F4A59F5667AD7C" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0G9</accession>
    <name>A0A518J0G9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cytochrome oxidase complex assembly protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_48590</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014807">
        <property type="entry name" value="Coa1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08695">
        <property type="entry name" value="Coa1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="158" mass="16736" checksum="67CEEB887897C18C" modified="2019-10-16" version="1">MSSYTPEDAFSPEPPKSRTAIKIIIAVVLIGLGIICCGCLGMIAVSWMAYGDSVETIKGNRVVQQNLGDVTTAEIDLQATGELAESGGQQQLVYRVEGTNGSGKVIVATGPAGLELKTLILEDGTEIDLQVQDDRIPVEFEIDSGELEIDTGDLVPQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0I5</accession>
    <name>A0A518J0I5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="11">D-alanyl-D-alanine carboxypeptidase DacB</fullName>
            <ecNumber evidence="11">3.4.16.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">dacB</name>
        <name evidence="11" type="ORF">Mal33_48780</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the peptidase S11 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.16.4" evidence="11"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009002">
        <property type="term" value="F:serine-type D-Ala-D-Ala carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018044">
        <property type="entry name" value="Peptidase_S11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001967">
        <property type="entry name" value="Peptidase_S11_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00768">
        <property type="entry name" value="Peptidase_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00725">
        <property type="entry name" value="DADACBPTASE1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="3" id="KW-0133">Cell shape</keyword>
    <keyword evidence="5" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="11" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022031294" evidence="9">
        <location>
            <begin position="29"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S11" evidence="10">
        <location>
            <begin position="47"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-ester intermediate" evidence="6">
        <location>
            <position position="78"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="81"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="138"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="255"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR618044-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR618044-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QDV58853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="312" mass="34109" checksum="091C7BAE5D352F18" modified="2019-10-16" version="1" precursor="true">MRQMASTYSTLLAFIMAALFISGGAAHATGPEVERPKKPADPLIGPPFVTCKAWVIADGHTGEILAGGNEDEQRNPASITKIMTALVVLKLAEESPDVWEETITFSERADKTVGSSCRLNAGESLPVKELLYGLMLPSGNDASVAIAEHFGPRLAMENENGYDAFIRTMCETAKQLGMERTSYVNPHGLTHETHLTTAADMVKLTCEAMKYERFRDTVATRNHSTIVNTPEGEDRTVSWTNTNRLLAQEGYLGVKTGTTTAAGACLVSCAERNEKRLVMVVLGSTSSDARYVDARNLYRWIWKEIAAESQDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0R0</accession>
    <name>A0A518J0R0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SASA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_49370</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001681">
        <property type="term" value="F:sialate O-acetylesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005181">
        <property type="entry name" value="SASA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039329">
        <property type="entry name" value="SIAE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22901">
        <property type="entry name" value="PTHR22901"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03629">
        <property type="entry name" value="SASA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021965170" description="SASA domain-containing protein" evidence="2">
        <location>
            <begin position="26"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="domain" description="SASA" evidence="3">
        <location>
            <begin position="109"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV58912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="486" mass="52839" checksum="C877DC9C2057450E" modified="2019-10-16" version="1" precursor="true">MFHRRQIFSLSIAMSLALVASSSHAEVKLASIFSDSMVLQRELPAPVWGWADAGEEVTVTLGSQTKKTKAGDDGRWQVQLENLQANATGQKLVVAGSNTIELNDVLIGEVWICSGQSNMEWPLSKATNGSEEVAAADHPQIRLFNVPGHTTSPVAKETCAGEWKVCHPGSAGGFSAVGYFFGRRLQKELNVPIGLVGTNWGGTRIEPWVSPEGFHKVPELKSIADQVDAYTAETKVGASSPSAIYNAMVHPLVPFSMRGAIWYQGESNGAEGESYYHKTRALVSSWRELFNPNLGFYWVQLADFKQPTDDPAGGDGWAKLREAQTKALDIDHTGMAVITDIGEANDIHPKNKQDVGDRLAQWALHQTYDKQQIVPAGPLFKSQKIEGDSIRLSFDYVGGGLIVGKKEGLAATEEVKQGKLARFAIAGADKKWHWADATIDGDTVVVKSAEVAEPVAVRYAYSMNPEGANLYNKEGIPASPFRTDAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0V9</accession>
    <name>A0A518J0V9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Threonine synthase</fullName>
            <ecNumber evidence="5">4.2.3.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">thrC_2</name>
        <name evidence="5" type="ORF">Mal33_50040</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="4.2.3.1" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004795">
        <property type="term" value="F:threonine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
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    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PALP" evidence="4">
        <location>
            <begin position="4"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="194"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV58979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="348" mass="36396" checksum="D18E347727E82041" modified="2019-10-16" version="1">MHDISLGEGNTPLVRSHRIGPELGLSNLFFKLETVNPSGSYKDRFAAAAISEMVRQGKRRVIATSSGNTGSALAAYCAAAGLGCKIAIVDGAPALKLRQMMAYGAEITKVRGFGLDADITRATFEVLQRMGDHPDAELQISAYHYSPIGMSAVEAIGREIVGQLSTQDKQADHVFSCAGGGGLTLAVARGVRDASEKGESGTTTRVHCVQPAGNNTIAGPLRDGSDHAQSVECTTKISGLQVATVIDGDAVIAACRESGGTGWLVEDAEIYRSQRDLARLEGIFSEPAGAVPLTGLKDAVAQGIIQPDQTVVCLVTGSGFKDLDSVDAMLGDNACPTVSLDEFQRDSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J178</accession>
    <name>A0A518J178_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_51130</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
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            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="152" mass="17792" checksum="45863B18DECB2B15" modified="2019-10-16" version="1">MKAATISQLKKELVKLEQDELLEVCLRLAKFKVESKELLTYLLMKADDEIGYANELCSEIDLQLNTPGRIHKKTLRKVVRWMDKSLRFSGNKETELHVRIHFCRRIQEKQISFGDCRVSANLYATQLKKIDKAIDKVHPDLRFDYRLQISGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J186</accession>
    <name>A0A518J186_9BACT</name>
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        <name evidence="3" type="primary">phoD_3</name>
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        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
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            <taxon>Planctomycetia</taxon>
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    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.3.1" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="F:alkaline phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
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        <property type="entry name" value="MPP_PhoD"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018946">
        <property type="entry name" value="PhoD-like_MPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038607">
        <property type="entry name" value="PhoD-like_sf"/>
    </dbReference>
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        <property type="entry name" value="PhoD_N"/>
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        <property type="entry name" value="TAT_signal"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16655">
        <property type="entry name" value="PhoD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="46"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="PhoD" evidence="1">
        <location>
            <begin position="154"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV59104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="518" mass="57932" checksum="7631760F939CF5FD" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1A1</accession>
    <name>A0A518J1A1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Efflux pump membrane transporter BepE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">bepE_4</name>
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    <organism evidence="6 7">
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        <lineage>
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    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042908">
        <property type="term" value="P:xenobiotic transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2090.10">
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    </dbReference>
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        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
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        <property type="entry name" value="HAE1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000731">
        <property type="entry name" value="SSD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82714">
        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00915">
        <property type="entry name" value="2A0602"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50156">
        <property type="entry name" value="SSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="343"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="369"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="396"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="440"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="472"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="548"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="877"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="903"/>
            <end position="927"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="933"/>
            <end position="957"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="982"/>
            <end position="1004"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="1010"/>
            <end position="1036"/>
        </location>
    </feature>
    <feature type="domain" description="SSD" evidence="5">
        <location>
            <begin position="372"/>
            <end position="497"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV59121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1048" mass="114063" checksum="F72862EC56F1507F" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1A6</accession>
    <name>A0A518J1A6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HTH-type transcriptional regulator MhqR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">mhqR</name>
        <name evidence="2" type="ORF">Mal33_51490</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HTH_MARR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="17"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="160" mass="18301" checksum="B72E5C0E500BFD9E" modified="2019-10-16" version="1">MKLQEELHRPVPFISLQQEALLNLLRIGDQLEVRLSRYFREHGLTLSRFNVLRSLLLAGRPLTCGEIGERMIQVVPAITSLVDHLENQGLVQRERCDEDRRVVHVRITKAGRKLADTAMQPLKGMETDLFAKLNSTELKSLIGLAEKVRESFVEYDKLPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1K1</accession>
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        </submittedName>
    </protein>
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        <name evidence="2" type="primary">iolE_3</name>
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        <lineage>
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            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
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    <dbReference type="EMBL" id="CP036318">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="27"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="295" mass="33401" checksum="B5E353539D5CB86C" modified="2019-10-16" version="1">MPKLAAFPKAFMHALCKDGTMTVSQWIDLASKLDVQGLEWYAGFLEMADQSNWARFRSEVEGHGMVIPMMCCSPDFTHPDAAFRDAEIAKQKRWIDMTAALGGSYCRVLSGQRRPELSIEQGVQLAADSIEACLPYAQDQGITLIIENHYKDDFWEFPEFAQQMDVFCMLVDRIDHPNFGVNYDPSNTYLAGEDPIELLKRVSRRVVTMHASDRYLKEGTLEDLRREEGGATGYAKRLSHGEIGKGLNDYDAIFSELRSVGFDGWISIEDGVDGMDQLARSVDFLKRKIAEYWPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J283</accession>
    <name>A0A518J283_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">arlS</name>
        <name evidence="10" type="ORF">Mal33_54810</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="169"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="9">
        <location>
            <begin position="193"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="8">
        <location>
            <begin position="254"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="468"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="481"/>
            <end position="499"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV59446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="499" mass="54878" checksum="81DB3905ECA5397F" modified="2019-10-16" version="1">MTQSIAWRLQMWHAAILVSVVVGLCTAWFLQARRARLNEIDAELTSAARVLDGSLRGFDLRSFDTTEHPISELLAADDHLRLSLPRELTDQRDNRPAPYFGIWLEDGRQLKSERLPEGFSLESSLSQPEAPERHGPNAILREVRIVGPAGSLILVGRDIGREIAELNRLALRIAAFAMLILAAGLCGGWWLARSVLRPIAAMSDAASRFSAADMSPRINVVETESELGQLATILNEAFDRVEQSFDQQRQFAADASHELRTPLAVIQSQIELALKRERTSEEYVKTLTTCSSASERLSDLVESLLTLARLDFSSQPTERVSVRVDLVAARCIDLMRPVAQQAEVNLRSELEPAIVSGDPKQIERVIFNLLKNSVAYNRPHGEVLLSVAVVGPSVELILRDNGIGISEADLAHVAERFYRADKARSRVHGGSGLGLSIAQGIVERHGGTMQIASQLDQGTMVTVHLPLASNRPRDSVKEPVDLISDNSTTARHTGTDPLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J2E0</accession>
    <name>A0A518J2E0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Beta-lactamase</fullName>
            <ecNumber evidence="6">3.5.2.6</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">cphA</name>
        <name evidence="6" type="ORF">Mal33_55400</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.5.2.6" evidence="6"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018741">
        <property type="term" value="F:alkyl sulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008800">
        <property type="term" value="F:beta-lactamase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018909">
        <property type="term" value="P:dodecyl sulfate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07710">
        <property type="entry name" value="arylsulfatase_Sdsa1-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038536">
        <property type="entry name" value="Alkyl/aryl-sulf_dimr_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029228">
        <property type="entry name" value="Alkyl_sulf_dimr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044097">
        <property type="entry name" value="Bds1/SdsA1_MBL-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14863">
        <property type="entry name" value="Alkyl_sulf_dimr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021806903" evidence="4">
        <location>
            <begin position="36"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="domain" description="Lactamase_B" evidence="5">
        <location>
            <begin position="74"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="172"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV59505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="469" mass="50955" checksum="F4A2C809AB3C0F07" modified="2019-10-16" version="1" precursor="true">MSKNRFSFDLSRFTLCAAKAWLLGIVALTATVAHGQTQTDPDTALRMLNAQQQQFEKGVIQVADNVFTAVGFHGANTSMIVGTDGVIIIDTLFGPSSAADAAEAFRQYSDKPVKAIIYTHSHGDHIGGASSFVGNAKPDIYATESFGSAEGVNKAVDPIKQKRNVRQFGRKLSPAESTNRGVAPAGTKDGDRGEGFLPPTVTVPNSGLKTTIAGIDIEFHISPGETDDAMFIWLPSEKVLFAGDNFYNSFPNLYAIRGTAYRDVLNWSESVGKMAALNPHVVVPGHTMPIAGEAAATAALQDYSDAIRSVYDQTVRGINAGKGPDQLAHEVELPEHLQDKPYLIQFYGTVPHAVRAIYCGLLGWYDGNPTTLNPLEPKIKAKKMAQLAGGTAELTAQMESALEKQDYQWALELSDHVKWLDDADRKLARKTKIAALRGLAAREYNAPNRNYYLSYANELESGQLSNVWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IM16</accession>
    <name>A0A518IM16_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Choline-sulfatase</fullName>
            <ecNumber evidence="11">3.1.6.6</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">betC_1</name>
        <name evidence="11" type="ORF">Mal33_00570</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="PTM">
        <text evidence="7">The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sulfatase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.6.6" evidence="11"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047753">
        <property type="term" value="F:choline-sulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004423">
        <property type="term" value="F:iduronate-2-sulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16030">
        <property type="entry name" value="iduronate-2-sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032506">
        <property type="entry name" value="DUF4976"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035874">
        <property type="entry name" value="IDS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16347">
        <property type="entry name" value="DUF4976"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0106">Calcium</keyword>
    <keyword evidence="5 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021810616" evidence="8">
        <location>
            <begin position="37"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase" evidence="9">
        <location>
            <begin position="38"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4976" evidence="10">
        <location>
            <begin position="393"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="modified residue" description="3-oxoalanine (Cys)" evidence="7">
        <location>
            <position position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR600917-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF16347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QDV54115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="500" mass="55641" checksum="1666CB50F8C9E977" modified="2019-10-16" version="1" precursor="true">MSSNATRSLFGCPAMRMLARVLFFASCLLLTSVASAAPNVLFIVADDLNCAISPYGDPVAKTPNLERLAQRGLTFTRTYCQQAVCNPSRSSFLTGLRPDTVKVDDLRKYFRNTAAGGSTLVTLPQHFKNHGYFCQNIGKMFHNMGDTQDRRSWSIDEVLFRGTHAADTIYNNTPSGGKPRQFKAPATEAHDVPDTAYRDGQIANLAAAMIRDHAVSDQPFFLAVGFWRPHLPFVAPRRYWDLYDADTIPMPEPVAAPEDVPAIAMHPSSEIRGYGGVPKDRPLSEAEVRHLRHGYYASISFIDAQVGEILDALDASGRADETIVVFTSDHGFHIGERTLWGKTSNFELDARVPLIVADPRHPASQGKSTPALAELIDLYPTLAQLAGISDDLPRRLEGTSLAPIFEDPKNSVKQAAFTQHQQPFYGNPSNWKAWGCSMRTDRWRYTRWTAIDSGDVIARELYDHDNDPLETVNLAADREHEKMIAEFDQTLANAFPERQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IM47</accession>
    <name>A0A518IM47_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein-L-isoaspartate O-methyltransferase</fullName>
            <ecNumber evidence="2">2.1.1.77</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">L-isoaspartyl protein carboxyl methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">Protein L-isoaspartyl methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">Protein-beta-aspartate methyltransferase</fullName>
            <shortName evidence="2">PIMT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2 5" type="primary">pcm</name>
        <name evidence="5" type="ORF">Mal33_00890</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>[protein]-L-isoaspartate + S-adenosyl-L-methionine = [protein]-L-isoaspartate alpha-methyl ester + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:12705"/>
            <dbReference type="Rhea" id="RHEA-COMP:12143"/>
            <dbReference type="Rhea" id="RHEA-COMP:12144"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90596"/>
            <dbReference type="ChEBI" id="CHEBI:90598"/>
            <dbReference type="EC" id="2.1.1.77"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.77" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004719">
        <property type="term" value="F:protein-L-isoaspartate (D-aspartate) O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030091">
        <property type="term" value="P:protein repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00090">
        <property type="entry name" value="PIMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000682">
        <property type="entry name" value="PCMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11579">
        <property type="entry name" value="PTHR11579"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00080">
        <property type="entry name" value="pimt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01279">
        <property type="entry name" value="PCMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021823968" description="Protein-L-isoaspartate O-methyltransferase" evidence="4">
        <location>
            <begin position="22"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="230"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV54143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="399" mass="44145" checksum="C0129076573720FB" modified="2019-10-16" version="1" precursor="true">MSLRPALLLSLVATVAPAVNAEDPYEAARKKLVRDRVAPAGVTDPAVLRSIETTPRHQFIPRKLWDQAYYDMALPIGDAQTISSPFIVAHMTEVLQCEPDDVVLEIGTGSGYQAAVLSPLVKHVYTIEIVEPLGIKAAATLKRLGYENVSAKVGDGFLGWPEAAPFDKIIVTCSPESVPQPLVDQLKEGGRMVIPVGERYQQTLYLMEKKDGKIVRQSLRPTLFVPMTGTAEDGRLKQPDPENPELVNSSFDLPSDDPEQVPGWYYGRQFNLMPDPTSGGNFVRFENETLGRDSHLLQGLALDGRAIARVRLSGNVRTQDVDSGGRPDRQPLLAVSFYDDKRRELGTFWIGPFPKEQDWTQHQRSFRVPPTTREAIVRIGLFGATGIADFDSVTLTPER</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMA6</accession>
    <name>A0A518IMA6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Peptidase family M50</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Mal33_01780</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase M50B family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008915">
        <property type="entry name" value="Peptidase_M50"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02163">
        <property type="entry name" value="Peptidase_M50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="54"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="115"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="173"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="204"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M50" evidence="8">
        <location>
            <begin position="166"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV54228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="259" mass="27874" checksum="76491495F3E29220" modified="2019-10-16" version="1">MLAEPGRTAYDVNFGLLGFPVRISIGFWIMALVFGYDLVTQLAQLFPGSRGPLLLLWILSVFVSILVHELGHALAMRACGQHASIVLYHFGGLAIPQNTFGAGFSKKNNSKAEKIFITAAGPLAQLMLAGIVIAVAKARGFEILLMPEFLASLPSLAGGQPIDSPGMFGLVNFLVWPSVMWALLNLIPVYPLDGGQIAKEIIELFGGTAYHAIVLSLVCAVLMAAWGVTSGRLFMTLLFVSLAYSNYEMLTGGGPRRRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMF5</accession>
    <name>A0A518IMF5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_02030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="59" mass="6246" checksum="1A028DBCA16238AF" modified="2019-10-16" version="1">MQLSRLTGTIAVTGPLLLMATAIELLSAWSGDQAFATFFGTIRIAMLVGLVVGLSIRDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMH3</accession>
    <name>A0A518IMH3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_02230</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007403">
        <property type="entry name" value="DUF456"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04306">
        <property type="entry name" value="DUF456"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="117"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="158"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="181" mass="18524" checksum="44D2F6F848413FD3" modified="2019-10-16" version="1">MEAWWHLIWPIGLILLTTVAWGSNFVTLPGNWIAAALVVVYFLVAPSDQRISLGTTEVVAAIGFAVLGEVLEFAAAALGAKKAGGSKRATVMAVVGSMVGAMGGALLGLPIPIFGTVIAALLFGALGATAGAVLGEWMSGKQWKETIPVGHAAFWGRLLGTVGKICAGIMILLVVIVGVCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMQ3</accession>
    <name>A0A518IMQ3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 13">Dihydrolipoyl dehydrogenase</fullName>
            <ecNumber evidence="3 13">1.8.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">lpdA</name>
        <name evidence="16" type="ORF">Mal33_03210</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>(R)-N(6)-dihydrolipoyl-L-lysyl-[protein] + NAD(+) = (R)-N(6)-lipoyl-L-lysyl-[protein] + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:15045"/>
            <dbReference type="Rhea" id="RHEA-COMP:10474"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="EC" id="1.8.1.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11 13">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="11 13">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="13">The active site is a redox-active disulfide bond.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.4" evidence="3 13"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004148">
        <property type="term" value="F:dihydrolipoyl dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006258">
        <property type="entry name" value="Lipoamide_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001100">
        <property type="entry name" value="Pyr_nuc-diS_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012999">
        <property type="entry name" value="Pyr_OxRdtase_I_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000350">
        <property type="entry name" value="Mercury_reductase_MerA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="SSF55424"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01350">
        <property type="entry name" value="lipoamide_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00076">
        <property type="entry name" value="PYRIDINE_REDOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5 11 13" id="KW-0274">FAD</keyword>
    <keyword evidence="4 13" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7 11 13" id="KW-0520">NAD</keyword>
    <keyword evidence="11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 13 16" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9 13" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="15">
        <location>
            <begin position="4"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="domain" description="Pyr_redox_dim" evidence="14">
        <location>
            <begin position="350"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="448"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="147"/>
            <end position="149"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="184"/>
            <end position="191"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="207"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="275"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="316"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="322"/>
            <end position="325"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="12">
        <location>
            <begin position="41"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012608"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="QDV54367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="475" mass="50135" checksum="BE226789C249CE02" modified="2019-10-16" version="1">MHSSLVVLGGGPGGYAAAFLAADEGLDVTIVEADSRLGGTCLLRGCIPSKALLHVARVISEVQELNEDWGVSYPGAPSIDIDKVRGRKETVISNLTGGLQALAKRRGVKVIHAKGVFENSTTLKLEGDHASIPEGGKITFDHCILATGSVPFVPPAFDIGSDRVMDSTGALELKDVPETMLVVGGGYIGLELGSVYAQLGSKVSIVELMDGLLPGADRDLVKPLQKRIEKLVDGRLFLNTKVGSLAEEKDGVHVTFEGPNKFGNEVYDRVLVSIGRRPVSKGFGLENTQVVVNAKGFVECDSQQRTADPHILAIGDVAGEPMLAHKANHEGRVAAEVVLGKNSAFDKVAIPAVVFTDPEIAWAGLTEGEAKAAGRKVDVEVYPWAASGRAQAIGRTEGSTKWLVDPETHRVVGCGIVGAGAGELIAEAVLAIEMGCEVHDITDSIHPHPTLSETLMNAGEVHFGTATEIYKPKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMQ7</accession>
    <name>A0A518IMQ7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Pheromone autoinducer 2 transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Mal33_03160</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002549">
        <property type="entry name" value="AI-2E-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21716">
        <property type="entry name" value="PTHR21716"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01594">
        <property type="entry name" value="AI-2E_transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="26"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="76"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="469"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="492"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="526"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="564"/>
            <end position="592"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV54362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="614" mass="68724" checksum="27E59D1FD214CE6B" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMU8</accession>
    <name>A0A518IMU8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glutamyl-tRNA(Gln) amidotransferase subunit A</fullName>
            <shortName evidence="7">Glu-ADT subunit A</shortName>
            <ecNumber evidence="7">6.3.5.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">gatA</name>
        <name evidence="9" type="ORF">Mal33_03660</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>ATP + H2O + L-glutamine + L-glutamyl-tRNA(Gln) = ADP + H(+) + L-glutamate + L-glutaminyl-tRNA(Gln) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:17521"/>
            <dbReference type="Rhea" id="RHEA-COMP:9681"/>
            <dbReference type="Rhea" id="RHEA-COMP:9684"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="ChEBI" id="CHEBI:78521"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.7"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="7">Heterotrimer of A, B and C subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the amidase family. GatA subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.7" evidence="7"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030956">
        <property type="term" value="C:glutamyl-tRNA(Gln) amidotransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050567">
        <property type="term" value="F:glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00120">
        <property type="entry name" value="GatA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000120">
        <property type="entry name" value="Amidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020556">
        <property type="entry name" value="Amidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004412">
        <property type="entry name" value="GatA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11895">
        <property type="entry name" value="PTHR11895"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="SSF75304"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00132">
        <property type="entry name" value="gatA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00571">
        <property type="entry name" value="AMIDASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Amidase" evidence="8">
        <location>
            <begin position="25"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7">
        <location>
            <position position="79"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7">
        <location>
            <position position="154"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-ester intermediate" evidence="7">
        <location>
            <position position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV54412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="493" mass="51922" checksum="50C41AC110578654" modified="2019-10-16" version="1">MTIPLDSAAKLLGLLASGELTARQATQASLDRIAATDPEVGAFTFVNTEAALAAADSIDQRRRDGQPLGALAGVPIAVKDVLCTTDMPTTCSSRMLENHMSPYDATVVARLRAADAVIVGKTNMDEFAMGASTETSAFGKTTNPWNPSLTPGGSSGGAAACVAAGDVPLSLGSDTGGSIRQPAAFCGITGLKPTYGRVSRYGLIAFASSLDQVGPMAFDAVDCATLLNAIAGVDASDSTSLPVETPDFTAGLDRIEGELRIGIVKHHLEAEGLDPEVRQAVDDAIEVFRDAGAKIVEVELPHSDYWVPTYYVIAPSEASSNLSRYDGAHYGHRSPVAASDAGDRGPLVATYCRSRGEAFGAEVKRRIMIGMYALSAGYGDKYYVKALQVRRLIRQDFDSAFQNVDLLLGPVTPTPPFAMGEKIDDPLQMYLCDLFTVGANLAGIPALSMPGGLTSNNLPIGIQLQAPPLQEAKLLQAAAAFQRATDWHTKRPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMX9</accession>
    <name>A0A518IMX9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dihydroorotase</fullName>
            <ecNumber evidence="2">3.5.2.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">pyrC_1</name>
        <name evidence="2" type="ORF">Mal33_03760</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.5.2.3" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004151">
        <property type="term" value="F:dihydroorotase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006221">
        <property type="term" value="P:pyrimidine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01317">
        <property type="entry name" value="DHOase_IIa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004722">
        <property type="entry name" value="DHOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="1">
        <location>
            <begin position="54"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="430" mass="46235" checksum="AF4F970392BC59F2" modified="2019-10-16" version="1">MTPLLIENGRLVDPSQSIDRVARVLVTGGLIAAINPDDGDLPPNVRRIDARGRIVAPGLIDLGTELREPGREEDETIETGGNAALAGGFTTILCAANTYPPIDSPGAVEFVRQKAQRARTCRIHVIACLSRGREGVDMAELGLLAEAGAVGFSDAPRPTSNSALLKKALEYCHMLDLPIYDLPLVPELTGSGVMHEGRVSTILGLQGLPTEAEDLAVTRDLRLAEATGGRLHIGPISTLQGVELIKRAKQRGISISASVWPQTLSSMTDRELESFDARFKVRPPLRNERHIEVCREALIDGTIDCISTGHTPRAREKKVNDLDLAPFGMVSLETTLASINTDMIRSGLLSWPDAITRLSTRPAEIAGVPGGSLKPGSPADIVIIDPDVAWTVRGDEFQSRSNSTPWEGKELFGQATHAIVGGEVRFERHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMZ8</accession>
    <name>A0A518IMZ8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Mal33_03960</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011429">
        <property type="entry name" value="Cyt_c_Planctomycete-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011478">
        <property type="entry name" value="DUF1585"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013036">
        <property type="entry name" value="DUF1587"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013039">
        <property type="entry name" value="DUF1588"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013042">
        <property type="entry name" value="DUF1592"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013043">
        <property type="entry name" value="DUF1595"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07635">
        <property type="entry name" value="PSCyt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07627">
        <property type="entry name" value="PSCyt3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07624">
        <property type="entry name" value="PSD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07626">
        <property type="entry name" value="PSD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07631">
        <property type="entry name" value="PSD4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07637">
        <property type="entry name" value="PSD5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022092150" evidence="1">
        <location>
            <begin position="23"/>
            <end position="1001"/>
        </location>
    </feature>
    <feature type="domain" description="PSCyt1" evidence="6">
        <location>
            <begin position="41"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="PSD3" evidence="3">
        <location>
            <begin position="127"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="PSD5" evidence="7">
        <location>
            <begin position="568"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="domain" description="PSD4" evidence="5">
        <location>
            <begin position="647"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="domain" description="PSCyt3" evidence="4">
        <location>
            <begin position="798"/>
            <end position="895"/>
        </location>
    </feature>
    <feature type="domain" description="PSD2" evidence="2">
        <location>
            <begin position="913"/>
            <end position="985"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV54442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1001" mass="112420" checksum="4FA80CBEC99BE5B6" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IN44</accession>
    <name>A0A518IN44_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">Polyphosphate kinase</fullName>
            <ecNumber evidence="6 7">2.7.4.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">ATP-polyphosphate phosphotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Polyphosphoric acid kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 12" type="primary">ppk</name>
        <name evidence="12" type="ORF">Mal33_04710</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7">Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>[phosphate](n) + ATP = [phosphate](n+1) + ADP</text>
            <dbReference type="Rhea" id="RHEA:19573"/>
            <dbReference type="Rhea" id="RHEA-COMP:9859"/>
            <dbReference type="Rhea" id="RHEA-COMP:14280"/>
            <dbReference type="ChEBI" id="CHEBI:16838"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="PTM">
        <text evidence="6 7">An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the polyphosphate kinase 1 (PPK1) family.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.1" evidence="6 7"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009358">
        <property type="term" value="C:polyphosphate kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008976">
        <property type="term" value="F:polyphosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006799">
        <property type="term" value="P:polyphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1840.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00347">
        <property type="entry name" value="Polyphosphate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003414">
        <property type="entry name" value="PP_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041108">
        <property type="entry name" value="PP_kinase_C_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024953">
        <property type="entry name" value="PP_kinase_middle"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036830">
        <property type="entry name" value="PP_kinase_middle_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025200">
        <property type="entry name" value="PPK_C_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025198">
        <property type="entry name" value="PPK_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036832">
        <property type="entry name" value="PPK_N_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30218">
        <property type="entry name" value="PTHR30218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02503">
        <property type="entry name" value="PP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13090">
        <property type="entry name" value="PP_kinase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17941">
        <property type="entry name" value="PP_kinase_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13089">
        <property type="entry name" value="PP_kinase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015589">
        <property type="entry name" value="PP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140356">
        <property type="entry name" value="SSF140356"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03705">
        <property type="entry name" value="poly_P_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1 6 7" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PP_kinase_N" evidence="9">
        <location>
            <begin position="12"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="PP_kinase" evidence="8">
        <location>
            <begin position="127"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="domain" description="PP_kinase_C_1" evidence="11">
        <location>
            <begin position="331"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="domain" description="PP_kinase_C" evidence="10">
        <location>
            <begin position="503"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="active site" description="Phosphohistidine intermediate" evidence="6">
        <location>
            <position position="435"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="375"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="405"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="468"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="564"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="592"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF17941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QDV54517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="704" mass="79749" checksum="C8321074EC113C6C" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IN73</accession>
    <name>A0A518IN73_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_04930</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="143" mass="16492" checksum="73521EC29DFF9680" modified="2019-10-16" version="1">MMPEPADDSANSPLSHLYELGKVTVFYLPSHKLDDPRYYQGTQTARTATHDFMMDRYRAYTHSPTPVKGYWVDFNGQLVHDVMERFEVSFGSEAEFERLIIFLIELCGRLSEDAVYVTRGERSFLVHGQPRQEIASDSGHDNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IN95</accession>
    <name>A0A518IN95_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Porin P</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">oprP</name>
        <name evidence="1" type="ORF">Mal33_05180</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023614">
        <property type="entry name" value="Porin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010870">
        <property type="entry name" value="Porin_O/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07396">
        <property type="entry name" value="Porin_O_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="474" mass="51611" checksum="FDC14A304B7749C3" modified="2019-10-16" version="1">MGYPLEQATRGNGWCRAVLASMGVVLLGSLATLDAQEPVLLPAVIDQPQVESESNIQWELQRLQQQIDELRAGAVTPVVCSPDPIAKPKFPSVRVTGLIQTDALWFDQDEANRTTLGAGDPVRGDIQDGADFRRARLAATGQAWDNVSYMLEMDFGFPGRPSFMDVWLDIDDVVGSNNLRIGQFRQPFGMDGLTSVREMTFLERGLPFAFLPFRQIGATLYGCDSDEVMTWAVSGFRYPTDFNGGNIGDNGGYGMAARLTGLLMNNGPGRGLVHLGGGYSFVDPSNDSFQYRSQPEVGIFETGGGVPAAAPTFVPPFVDTGIFQANNSNLFNVEFATALGSFYSQSEFYFVVVDRPGQSTVGFTGAYSQVGYFLTGESRTYNSKGGVFGRVKPNHSVGRGGGLGAWEVAGRWSYLDLTDDDILGGTLNDLTAGLNWYINPFTKFQFNYIYAMLDNPIYGDSEAGIFAMRAQVDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INE1</accession>
    <name>A0A518INE1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_05550</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="282" mass="28107" checksum="1DA07E05E971C3BB" modified="2019-10-16" version="1">MKRAILSTTLIIGMSICSQGFGFDLLDRMLGLKCGGGSSSCCETGCADVCEPACGCETSCCESVCEPACGCEASACGTSCCEPTCGVESSLCGASCCEPACGCETSCCEPACCDSKSCFGSKKKCCGLLSKLFGGKKNGCDSCCETSACCEPACGCEAAACCEPACGCETSLCGSASCCEPACGCDPCGKKKSGGLLSKLFGGLKCCKKSDCDSACDSCGCAGSYAAPAAPACSSCNGGTSVQVEAPVVEDAAPMPPAPVVDPSAYLNSKRRVIQASTRYAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INF8</accession>
    <name>A0A518INF8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_05720</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="179" mass="20529" checksum="1446A06E380950DA" modified="2019-10-16" version="1">MKFTIVVAVSFFVLLWRPELSLASDYDAVVAAVRFFEKSQLSGQVDEVEPLLKKGATRKRGKPGSLIEILRREQEHIRKTAPMQEVRLREIYVVREDEQEQLKDRTLRYMRAKGKNVTDEEADVPADVIAKAYGLTENRTVCMLFYELSRGEDAISVNLVLVALEEIEGKFLVAHVWDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ING3</accession>
    <name>A0A518ING3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Outer membrane biogenesis protein BamB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_05570</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018391">
        <property type="entry name" value="PQQ_beta_propeller_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002372">
        <property type="entry name" value="PQQ_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13360">
        <property type="entry name" value="PQQ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00564">
        <property type="entry name" value="PQQ"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021711356" evidence="1">
        <location>
            <begin position="23"/>
            <end position="741"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="741" mass="81166" checksum="0CCB5DF37E558F8A" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ING5</accession>
    <name>A0A518ING5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Outer membrane biogenesis protein BamB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_05890</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018391">
        <property type="entry name" value="PQQ_beta_propeller_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002372">
        <property type="entry name" value="PQQ_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13360">
        <property type="entry name" value="PQQ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00564">
        <property type="entry name" value="PQQ"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022182272" evidence="1">
        <location>
            <begin position="28"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="449" mass="49891" checksum="108592F04D4ECF52" modified="2019-10-16" version="1" precursor="true">MFRQTRLDLFFLSMAVLILCGSTRASAEDWPQFRGPESRGVSEAMELPDRWSESENVVWKTPIAGRGWSSPIVVGERVFLTTVTRNTGKPEDAKPGLYFGGNREKPADVPHAWKAICLDRKSGKPLWEKTLHQGKPATSRHIKNSYASETPVSDGEHLYVLFGDVGLYCLTVDGDLVWQKELPPCKTRYDWGTAASPVLHEGRLYLISDNEDASYLAAIDAKTGEQVWRVERDEKSNWSTPFIWKNELRTEIITPGTGRIRSYDLDGKLLYELSGCSSITIAMPYAAHGLLYVSSGYVNDDMRPIFAIRPGASGDISLRGEATSNEFIAWCQPKAAPYNPSTIVYGDQLYVLHDRGLMASYDALTGEVIYEKKRIPGGRSFTSSPWAYEGKIFCLNEFGKTLAIAAGPEFKLLQTNELDSTELCMTTPAIADGQLILRTGDAVYCIAKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INI2</accession>
    <name>A0A518INI2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4159 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_05950</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025297">
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    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022128109" description="DUF4159 domain-containing protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4159" evidence="2">
        <location>
            <begin position="57"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="275" mass="32019" checksum="FA05B57037E5353D" modified="2019-10-16" version="1" precursor="true">MNRKPMIIAGLLLAIAVTSLAMAQRWRRDRNRDWQSAGRGDVPDWETNADFPNDMFTFVRIKYQSAGWGRGGGWDTDYRDSDLNFSLRLHQLTSLNVNPEPIVLELTDPKLFDYPWIYIIEPGRLMFTQPEVVALRRYLDNGGFLMIDDFWGDEEWQNLYYQMKRVFPDREPEDVPLSHEIFQCVYPLKIKPQVPSIGAWGGRGSRTWERGPDTQTPNYRSITDDAGRIMVFICHNTDLGDGWEREAESPDYFEEMSVKYAYPLGINIVTYAMTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INI6</accession>
    <name>A0A518INI6_9BACT</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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    <organism evidence="1 2">
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        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetia</taxon>
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="517" mass="58541" checksum="67CE79D34D1D1F57" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INN6</accession>
    <name>A0A518INN6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_06580</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022165978" evidence="2">
        <location>
            <begin position="18"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="185" mass="20193" checksum="DF2892C6FFD81CBE" modified="2019-10-16" version="1" precursor="true">MRILILTAVVTMIAANACPAQVVMLPTLGTFQYSGSVLVPDGGSAHLGSIGRSAESSRKSGWGSRSTGRSISRGTMSAHVQIIDLAEMDRQLLGAEPAEFLRQQKAKENAAAKVVPPKPIDPVEAAKQLVRDARRCVQEGHLKAADYYYRRAIGELPSDLAAIAQREYDRFGQQRHLLARRQMQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INQ5</accession>
    <name>A0A518INQ5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_06780</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="465"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="9"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="79"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="138"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="229"/>
            <end position="283"/>
        </location>
    </feature>
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        <location>
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            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="472"/>
            <end position="496"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="QDV54721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="507" mass="58751" checksum="A6D264F49CDC44D7" modified="2019-10-16" version="1">MPTSGSEVLREMTRAIQNAKRQRDALQSQHREILQQTDDLVGQRGQTLVELAESYLPELSQTTVRQVWNEIRPAIQDVLLRKEARHRELVAEHQRLEAAQTQLRGELQTLNGKLDAIYGERDSLSKQLSEQLSGDPAFQQLTDKAAIAEINLQRAESSLAEVEHDVIAKLPAYQRSRLFQYLHKRKMGTPQYTARGWRRRMDRWVGRLIDYPKARKSYEFLSEVPGKMRELIAERRDALNQLLDRLERSQHKVAAELGLDKVLDQIESREDQRNDLLEQLEQTVVQTNANGAEIDKLLDSEGPYYAEAIEKYRRLLEQTHTLTLEQRAAQSPDPIDDQLVARLKHLDEEIQQFQKAADARRRQLKEAEDFAESIDYLVQQFQRARFDDSRSYFDDKLNIRESLSRLADGRERPDLLWQHIRRHQHTAPNWYEENSRRVVNAANSPMGQILLQTMAHAAGAALRENARRAGSRRMSYPTSSTRSTSRTTSRPRMPTPKRSGFSTRKGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP39</accession>
    <name>A0A518IP39_9BACT</name>
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        <submittedName>
            <fullName evidence="8">Cytochrome c</fullName>
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        <name type="scientific">Rosistilla oblonga</name>
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            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Rosistilla</taxon>
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    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
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        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002327">
        <property type="entry name" value="Cyt_c_1A/1B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013427">
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00034">
        <property type="entry name" value="Cytochrom_C"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02603">
        <property type="entry name" value="CxxCH_TIGR02603"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02604">
        <property type="entry name" value="Piru_Ver_Nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="7">
        <location>
            <begin position="864"/>
            <end position="996"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV54865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1000" mass="110101" checksum="B7DDC9EC46F5F463" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPJ8</accession>
    <name>A0A518IPJ8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_09890</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SCO1/2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02968">
        <property type="entry name" value="SCO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003782">
        <property type="entry name" value="SCO1/SenC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12151">
        <property type="entry name" value="PTHR12151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02630">
        <property type="entry name" value="SCO1-SenC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0186">Copper</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="4">
        <location>
            <begin position="60"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV55021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="230" mass="25974" checksum="4E0E70D52F4205FB" modified="2019-10-16" version="1">MNRTAMHVMVILITGMVIGLIARSRRIEREQAEAAQVQMEAEVAEAAVAEQSAAKEPVVVEGDGWLSEFELTERSGETVSSKELLGQPYVVSFFFTTCPSTCPMQNEKLKILQEEFYGKGVRFLSISCDPEIDTPEVLSEYAKRFEADKDQWLFLTGELNYIRRVGAEVFRLPVNRRFHTDRFVLVGADGEIVALYEWPEPEQFDRLKKDIGKLLAGEKIDDSKDEGNAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPM5</accession>
    <name>A0A518IPM5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Basal-body rod modification protein FlgD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">flgD</name>
        <name evidence="3" type="ORF">Mal33_10010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FlgD family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044781">
        <property type="term" value="P:bacterial-type flagellum organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005648">
        <property type="entry name" value="FlgD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03963">
        <property type="entry name" value="FlgD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1005">Bacterial flagellum biogenesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="145" mass="15365" checksum="5E853EDA8FE7EAD8" modified="2019-10-16" version="1">MSQIAATGATSSASSSADAAESGLNDLNLDDFLTLLITEMQNQDPLNPMENAEMLQQIGQIREIGATNDLTETLGNLSLSQQLTTASNLIGREVSGLSDDSEEITGKIDRVSVETDSDGGDSRNVKVHVGEKTIQVSNIREIVEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPM8</accession>
    <name>A0A518IPM8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_10170</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="148"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="174" mass="19097" checksum="03E13D940158D7CB" modified="2019-10-16" version="1">MHLFTCPCGESFPISAAQAGQSIQCPHCNQSVQLPKLRDLKQLPVTQAAEEASPSRGWSAPQGVLFSVIFACLVASLGMSAWSSYRWLQIEKPPTPEAMIAMGQEEIENHSAAQLLEFWVNYGQPGMGTRRMPGYAQVDAYRESWKHWAFGAYAATAVSLCGLIFVVTKRSSGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPR3</accession>
    <name>A0A518IPR3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acetyl xylan esterase (AXE1)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_10550</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008391">
        <property type="entry name" value="AXE1_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05448">
        <property type="entry name" value="AXE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021807542" evidence="1">
        <location>
            <begin position="25"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="domain" description="AXE1" evidence="2">
        <location>
            <begin position="230"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="708" mass="76575" checksum="16761AD6B6D86F8C" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPU8</accession>
    <name>A0A518IPU8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_10590</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="188" mass="20990" checksum="108CB898A8949F39" modified="2019-10-16" version="1">MANDPIDLLAPGLRGWTIADRFDFAERGEISLDSGTLSIGKGRPASGLSYRGPQPGDFYRIAWEARRTAGSDFFCGLTFPIRGSHATLIVGGWGGGVIGISNIDNMSAVENPTTEYREFELNRWYRFEMEVNKTAVLFAIDGERVIDLDHDEHKYSVWWEQEQMAPIGLATWDTASEIRKLTLTNLDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPW0</accession>
    <name>A0A518IPW0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Coproporphyrinogen III oxidase</fullName>
            <ecNumber evidence="6">1.3.3.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">hemY_1</name>
        <name evidence="8" type="ORF">Mal33_11000</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>coproporphyrinogen III + 3 O2 = coproporphyrin III + 3 H2O2</text>
            <dbReference type="Rhea" id="RHEA:43436"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:57309"/>
            <dbReference type="ChEBI" id="CHEBI:131725"/>
            <dbReference type="EC" id="1.3.3.15"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="6">Porphyrin-containing compound metabolism; protoheme biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.3.3.15" evidence="6"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00252"/>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004729">
        <property type="term" value="F:oxygen-dependent protoporphyrinogen oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006783">
        <property type="term" value="P:heme biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004572">
        <property type="entry name" value="Protoporphyrinogen_oxidase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00562">
        <property type="entry name" value="proto_IX_ox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6" id="KW-0274">FAD</keyword>
    <keyword evidence="2 6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5 6" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="4 6 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amino_oxidase" evidence="7">
        <location>
            <begin position="23"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV55131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="487" mass="52778" checksum="271D6DB65CD966E9" modified="2019-10-16" version="1">MPDPAPQPTPPRHARVAVIGGGISGLVAAFDLRHRHPDWDVVLYEASDRVGGVIRTLRQDDFLLEFGADSFSVQPPGALQLCRDLGIEDRLVDPLEANRRAFILHAGKLVPVPEGFALLRPTDLKKLLASPLLSIPGRLRLVAEAFIRGKSDDSDESLQSFAIRRFGREAFDRLIQPLVAGIYTADASKLSMRATMPQFVALEAEHGGMVRATRALQKQSKDDAARSASGARYAQFRSLPGGMGELFDTLVDRIGETNIRRGQRIASLQQAGDSWNIESDRGEAASYDAVIVALPGPAASALLRPLAREAADELAEIPYASSALVLLGVGKDQVAHPLDGFGMVVPAIEKREIIAASFLNRKFADRAPDDMHLIRVFIGGAMQSHLLERSDDELIETARRELAAMIGLQGPAKIQRVARWNNAMPQYHVGHCDRRDRVELAIGQLPGLELAGNALHGVGIAHCIRTARAAADRIGKHLASQLGDSPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPW5</accession>
    <name>A0A518IPW5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_11040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="103" mass="11708" checksum="2E211F9F7F53DAAB" modified="2019-10-16" version="1">MTNLEPSPEALKFRGSMRAGSFTAQLFVELAVEPSSLTLSASMRSFRIDRENFQGLEETSILGIFKRGIRFRHSQPGLTNPIIFYPSMNRDAFRQHLQSIGWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPY1</accession>
    <name>A0A518IPY1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_11010</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04276">
        <property type="entry name" value="ZnMc_MMP_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033413">
        <property type="entry name" value="DUF5117"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032534">
        <property type="entry name" value="EcxA_zinc-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034032">
        <property type="entry name" value="Zn_MMP-like_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16313">
        <property type="entry name" value="DUF4953"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17148">
        <property type="entry name" value="DUF5117"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022109127" evidence="2">
        <location>
            <begin position="29"/>
            <end position="1007"/>
        </location>
    </feature>
    <feature type="domain" description="DUF5117" evidence="4">
        <location>
            <begin position="95"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4953" evidence="3">
        <location>
            <begin position="570"/>
            <end position="888"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="497"/>
            <end position="566"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV55132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1007" mass="113651" checksum="416306434DD94414" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPZ2</accession>
    <name>A0A518IPZ2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_11350</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="26"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="115" mass="12565" checksum="98A08CAC656A6050" modified="2019-10-16" version="1">MNHNPYSSPNATLVDDERKSSRPCTVMFWLSCVLSLGMFAIAAMGGYQYWVYKSQAGFKLPPYVLAVTVCVACSGLGMLYSAIRWRCQLIRAAAVSFGCSLLAFFVGPALLPLLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQ44</accession>
    <name>A0A518IQ44_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Serine/threonine-protein kinase Pkn1</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">pkn1_2</name>
        <name evidence="2" type="ORF">Mal33_11620</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="24"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="294" mass="32357" checksum="AA42E96A02DB8FC5" modified="2019-10-16" version="1">MTDRTGVTTDRVPSAKRNQCVGIWRLLECFHQGPWTDLFYAQPAEAAGSPRADYVVKMVTDSIDAQLEGQLQLRQEATSAQAASHPNLIALLDARLSAPRPYVVFPRLDGQPLSTWLGSKYSQPLPVGLWWIRQAAQALQALHQSGWIHGDVKPDNMLVSLSGHLTVIDLGLSMREGDTLQADRFQGTPAYAAPEQIQGKGRATSQSDIYSLGIVFQQMLCRNKPAVPAKPLNRQLLQKFQVPESVVGMLEEMTSPTATDRPTAAQLVDRIFKLEIETLGTHIQPLDDTLPQAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQ51</accession>
    <name>A0A518IQ51_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">UDP-D-galactose:(Glucosyl)lipopolysaccharide-1, 6-D-galactosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_11880</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="189"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="391" mass="43175" checksum="3457E44F86FF568F" modified="2019-10-16" version="1">MDIKCNQQSPGNQSSAAPRDLVKSKKLDKILIVQNKIPHYRKAFYNALAQHYDVHVIHSGEASRAPGDLYRESVVRVRSVGPFRFQSNVLREVTGGEYLATILMFDIRWCNSFLSLIRGTKSRVLLWGHRYSDSWLANKVRTGLMPYADGMIQYGGEGIARMVVEGTDPAKIFVAQNTIEVLNHADGSSERKSSFLFVGRAQKRKKVDQLLYAFAEVVNSLPSRVTIDIVGAGGENVRLACLAKELGISDRVIFHGAITDETQLKRLFHRSFAYVSPGPVGLGVLHSLAYGVPVVTGVLGKHGPEFEHLREGSNAILFRSTAELSRILTDLSHSPRKASSLGKNAYEHYLREGLLAGMVEGFIQAIENRPQVQANAKESAKQSQAKMSQAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQA3</accession>
    <name>A0A518IQA3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Dihydropteroate synthase</fullName>
            <shortName evidence="1">DHPS</shortName>
            <ecNumber evidence="1">2.5.1.15</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Dihydropteroate pyrophosphorylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">folP</name>
        <name evidence="3" type="ORF">Mal33_12100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 7,8-dihydrofolate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate and 4-aminobenzoate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DHPS family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.15" evidence="1"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00077">
        <property type="reaction ID" value="UER00156"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004156">
        <property type="term" value="F:dihydropteroate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046656">
        <property type="term" value="P:folic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00739">
        <property type="entry name" value="DHPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045031">
        <property type="entry name" value="DHP_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006390">
        <property type="entry name" value="DHP_synth_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011005">
        <property type="entry name" value="Dihydropteroate_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000489">
        <property type="entry name" value="Pterin-binding_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20941">
        <property type="entry name" value="PTHR20941"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00809">
        <property type="entry name" value="Pterin_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51717">
        <property type="entry name" value="SSF51717"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01496">
        <property type="entry name" value="DHPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00792">
        <property type="entry name" value="DHPS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00793">
        <property type="entry name" value="DHPS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50972">
        <property type="entry name" value="PTERIN_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0289">Folate biosynthesis</keyword>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pterin-binding" evidence="2">
        <location>
            <begin position="18"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU361205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="279" mass="29906" checksum="7DA466FD72AEE760" modified="2019-10-16" version="1">MPPIWKLPKRSITFESTPVVMGILNATPDSFSDGGRLADCTAAVDAALAMEDAGAGIIDIGGESTRPYAPAVDADEELRRVVPVIQQLQGRLSCPISIDTSKAVVAQAAIDAGAEIINDVSGLQGDPQMFDVAARNAVAVCAMHMQGTPQTMQDDPRYDNVVHEIYQYLADRKQQCLDNGIEAQRICLDPGIGFGKMHEHNIELLRGVSEFLKLGVPILIGHSRKGFIGKQTGDDLILRDAGTVGVSLAMAAAGMHILRVHNVPMTVAALKLFQQCQPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQD2</accession>
    <name>A0A518IQD2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_12300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008930">
        <property type="entry name" value="Terpenoid_cyclase/PrenylTrfase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48239">
        <property type="entry name" value="SSF48239"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="350" mass="38489" checksum="D46AB6EF643737F1" modified="2019-10-16" version="1">MSLSLSRRAMLRDTAAAGLALSLAAGSAPRAVAAKRDPRWEESIQRGLDWLARTQSSRGQWNAQHYPTALAALAGAAMIGSGSTTTQGPYARPIARATDFLISKCRDNGLIGDPLTDSRYTYGHGFSMLFLSQVLGEEGLVDRRRELVDVLSKAVQFSGYAQTPAGGWGYVSARDGNNFDEGSTTITQVQGLRGCRNAGIPVPGEIIEKAKQYIYECKNADGGISYSSRQTGSSRPAITAAALAALYNAGDYDGEHVPDMLDYAKKSLHRISGEQQAYGHWHYTYLYYSQVVYRQGEAEWAPFRDKLYDRIVGEQKADGYWEGQIHPVYVTACNLIMLQLDKGYLPIYQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQE1</accession>
    <name>A0A518IQE1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MazG nucleotide pyrophosphohydrolase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_12430</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004518">
        <property type="entry name" value="MazG_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03819">
        <property type="entry name" value="MazG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MazG" evidence="1">
        <location>
            <begin position="33"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="106" mass="11716" checksum="24C6F6C02A5FB328" modified="2019-10-16" version="1">MNEPKPEISLTDFQQKIKAMYYEKDVVRGVDGTFMWLMEEIGELAAALRGDDRENLAAEFADVLAWLATIANVADIDLSKAISEKYGSGCPGCSRLVCICPNEEKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQX2</accession>
    <name>A0A518IQX2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_14590</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="131" mass="13810" checksum="62900ACB35B2620C" modified="2019-10-16" version="1">MLHETNRRGNVPSTRQADMFPAFDAAAMASMKPREPQRRPHSSKATSLAAYRDGRPRAGTKAAIALNAIIEAGKAGLTRYETCESTGIGYCSIAAPVLALLNAGLIVELAATRPTPTGSPAHVLVAKEALR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IR18</accession>
    <name>A0A518IR18_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">LssY_C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_15060</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025902">
        <property type="entry name" value="LssY-like-C_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14067">
        <property type="entry name" value="LssY_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="domain" description="LssY_C" evidence="2">
        <location>
            <begin position="55"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="245" mass="27381" checksum="BDEAD943AB349F4D" modified="2019-10-16" version="1">MDTEPDPTPRQRTRKSQFIRVVAVILLLWIVVAYAVAPWVWEAFTESDPMDGESQRITRTSDGHPGDPLNVALFGSEVEMQEIMRAADWYSAAALGLKSDLKIAADTVFSRPDDAAPVSSLYLFGRKEDLAFEQPVGDNPRHRHHVRFWKTEDVNAAGQPKWIGSAVYDERVGLSHTTGQITHVTAPNIDAERDYLFQCLEQTGQLAEHSVEADYHQRREGTNGGGDPWYTDGSLYIGVIRAESP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRC9</accession>
    <name>A0A518IRC9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">3-hexulose-6-phosphate synthase</fullName>
            <ecNumber evidence="3">4.1.2.43</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">hxlA</name>
        <name evidence="3" type="ORF">Mal33_15700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="4.1.2.43" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043801">
        <property type="term" value="F:hexulose-6-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004590">
        <property type="term" value="F:orotidine-5'-phosphate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04726">
        <property type="entry name" value="KGPDC_HPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041710">
        <property type="entry name" value="HPS/KGPDC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001754">
        <property type="entry name" value="OMPdeCOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00215">
        <property type="entry name" value="OMPdecase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00934">
        <property type="entry name" value="OMPdecase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OMPdecase" evidence="2">
        <location>
            <begin position="4"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="232" mass="24716" checksum="278119606E477599" modified="2019-10-16" version="1">MKPIVQISLDLTTIAEALETAELAIRAGVDWIEAGTPLILAEGLHGIRALRERFPDVPIVADLKTMDGGYLEAEMMAGAGATHVVVMAQAHDETIECVVKAGRDYGVGVMGDNMAYDTMVDGARRLEDLGCDYIVHHIGYDHRRGIAAAGGRMPSPLDDLRAVVDAVKIPVQAVGGLSIEEAIQCPAYGAPLVVLGAPLTIDADAFKTADGDLESSLRLICEKVHAYDEVQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRK8</accession>
    <name>A0A518IRK8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_16970</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="56" mass="6431" checksum="063E669687CA554B" modified="2019-10-16" version="1">MDKKAKKRLDVINKKLSQLRQNLAGVRQQADEPDEITNLEKEIAKLEAEAVELRKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRL1</accession>
    <name>A0A518IRL1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_17060</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025975">
        <property type="entry name" value="Polysacc_lyase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14099">
        <property type="entry name" value="Polysacc_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="273" mass="30397" checksum="1B0E36CBE96321B2" modified="2019-10-16" version="1">MRRQTIEFAIALGLAVVVGCGAKKQDRSLEEMYLETIMPDDLVAIANVDVATAESIAIVDDPRGRCLGLRIAPDQPKLHGGVRAEVSVDFPFTENDRVRYAWRFRFADDFISDDPQNRWWVIGQWHDQPDARQNETWETFESRSPPIALGIGDVDGQLSVGMTYGVTKDNQPQFVSAPVPIERGDWVAVEALVHWSQGAEGRAEFFIDGSAEPSMVATGPNMNNGYQHYLKIGMYRHPDIETENWIYIDDVSIVQADDAVEAQRSPEASGSGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRT7</accession>
    <name>A0A518IRT7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_17840</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="125"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="163" mass="17746" checksum="1A79CAA75D81CA2D" modified="2019-10-16" version="1">MDTQLLIDTLSRVIHVATAITLVGGSAFMLLVLIPAAQNLSDEEHARLRTGLIARWKRFVHIGVTLFLISGLYNYYRAIPSHKGDGLYHALLGTKMLIALVIFFIAAALVGRSAKLEPIRRKRTLWLKVLLICALIVVTISGFVKVRGPQPPAAAQAPAAVAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IS34</accession>
    <name>A0A518IS34_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Competence-damage inducible protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">cinA</name>
        <name evidence="2" type="ORF">Mal33_18850</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd00885">
        <property type="entry name" value="cinA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.980.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041424">
        <property type="entry name" value="CinA_KH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008135">
        <property type="entry name" value="Competence-induced_CinA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036425">
        <property type="entry name" value="MoaB/Mog-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001453">
        <property type="entry name" value="MoaB/Mog_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18146">
        <property type="entry name" value="CinA_KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00994">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006728">
        <property type="entry name" value="CinA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00852">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53218">
        <property type="entry name" value="SSF53218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MoCF_biosynth" evidence="1">
        <location>
            <begin position="6"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="414" mass="45779" checksum="1518AE925CDA4137" modified="2019-10-16" version="1">MTICAEVIAIGDEITSGSRLDTNSQWLASQFGELGVRTLYHSSVGDDFDACVDVFRIAIGRSDYIIMTGGLGPTQDDLTRKAIAAATDRPIEIRQEALDHIQSFFVGREMPDRNRLQAEFPQGSRLIHNPHGTAPGIDLTVERPGRPDCHVFCLPGVPAEMRQMWNAGVAVRMRELLGVQRVVRQHVVKCFGVGESDMESRIADLLDRKQTPQVGITVNRATISLRIFAEGSDEADCQSQIDRVTESLRQRVGEFIFGEGDDFELQDAIIELLDRRGETLCCVEHGFNSLADTWLSACERPDLYRGGLSLSDQRASNRWRSVLGVPQNGSPEQWTAEVMERFDADWALAIDGYPTIVPGEGKTNPSSDIRLVVTGRKLATPRSITFHMGGHPDVLPPRIGKAGLNFLRQVLLAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISB7</accession>
    <name>A0A518ISB7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Isopenicillin N epimerase</fullName>
            <ecNumber evidence="2">5.1.1.17</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">cefD</name>
        <name evidence="2" type="ORF">Mal33_19610</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="5.1.1.17" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045439">
        <property type="term" value="F:isopenicillin-N epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminotran_5" evidence="1">
        <location>
            <begin position="34"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="391" mass="43157" checksum="9F23D9E6D43F23EF" modified="2019-10-16" version="1">MNDSATGQHRREHWRLNPAIDFLNHGSFGATPTVVLEAQRRFRDAMESDPIEFLAPERELLPKLDRVREVIAQLVNADARDIAWVRNATDGVNAVVQSFPLKPGDNVVVTNHGYNACSNAVRYAAERCGAEVRVAEIPFPIASPDEVVDAIERTIDDATRLLLVDHVTSPTGLVFPIEAIADVARRRGVRVLVDGAHAPGMVAIDLPRLGVDYYTANHHKWLCAPKTSGFLWVKPELQAQVRPTVISHAANRPIDGRSRFLSEFDWTGTFDPSPLLAVPAAIDFLDSLYPGGLTELMQSNHRLALQSRDRLCAALEIAPPAPDSMLGSLVALPLPVSDAPLQKILRDQHGFEFPIYPGPKPDTRLMRVSLQAYNDVEQIDRLADLLPKLLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISI7</accession>
    <name>A0A518ISI7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">SpoVR family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_20280</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007390">
        <property type="entry name" value="Spore_V_R"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30029">
        <property type="entry name" value="PTHR30029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04293">
        <property type="entry name" value="SpoVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="514" mass="60013" checksum="8896C9619FA1A354" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISL9</accession>
    <name>A0A518ISL9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Autoinducer 2 sensor kinase/phosphatase LuxQ</fullName>
            <ecNumber evidence="7">2.7.13.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">luxQ</name>
        <name evidence="7" type="ORF">Mal33_20630</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.13.3" evidence="7"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="1 2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PAC" evidence="6">
        <location>
            <begin position="229"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="4">
        <location>
            <begin position="299"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="5">
        <location>
            <begin position="547"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="272"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="601"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV56084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="672" mass="75372" checksum="A5A55EEE213DAFB9" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISR9</accession>
    <name>A0A518ISR9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">prkC_6</name>
        <name evidence="8" type="ORF">Mal33_21080</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="30"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="59"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV56129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="504" mass="55607" checksum="C5ACBEDC1FF980A9" modified="2019-10-16" version="1">MTDTSNVPPGDSLAAHEIGNDLTGGQLGDLQILRRLGRGGMADVYLAKQVSLERQVAVKILRASLANDNNYVERFRREARAAAKLSHPNIVQVYDVGRSDGRYYISQEFVDGRNLREQVDREGPLSLQRALDVMLGVAAALDAASEQGITHRDIKPENIMLSSKGNVKVADFGLARIANPDFQSELTQVGLTLGTPLYMSPEQVQGKPVDVRSDLYSLGVTMFHVLTGRPPFEGETPLAIAVRHLHETPPRISAMRMDDHVPDWVDEVVARLMAKDPKQRFDSPSRLVDYLHKKVDQSGGQETLGTLPVRLAATKTLQSVMSSEPTSTARRLLWLAAIALPLMGLAAGIVSARHRSDVADLLSTEAATVQPQESVQRQFFEAMRINTPAAWQAVWVSFPEAKSAENKIYAAKARIQLARLYDQQNLPESAERLARQVMNDPDLPPHLTAIAMAQCENALRGMNKHDEAAQLGDSLNRKWKELSTEGQSLFRIAVPRGVLDRLEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IT90</accession>
    <name>A0A518IT90_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_22650</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="152" mass="17371" checksum="25BFD750543F00D1" modified="2019-10-16" version="1">MKTKQYQLTKAEKALLDRIQERGNDAVCNLMATKMYREQMSVHRGAMWIDDEFPEAEGECLIFGNDSFTSDVRARKEVAQVIARLDSLAIRVFGFGLGPDGYTWALRVDSDDEELLDLIVWDVWFDITCGKANPMKDELNEYLDEMGYDVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IT95</accession>
    <name>A0A518IT95_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">UDP-glucuronate decarboxylase</fullName>
            <ecNumber evidence="4">4.1.1.35</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">arnA</name>
        <name evidence="8" type="ORF">Mal33_22890</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Nucleotide-sugar biosynthesis; UDP-alpha-D-xylose biosynthesis; UDP-alpha-D-xylose from UDP-alpha-D-glucuronate: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.35" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00796">
        <property type="reaction ID" value="UER00771"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048040">
        <property type="term" value="F:UDP-glucuronate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042732">
        <property type="term" value="P:D-xylose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033320">
        <property type="term" value="P:UDP-D-xylose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044516">
        <property type="entry name" value="UXS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43078">
        <property type="entry name" value="PTHR43078"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="7">
        <location>
            <begin position="6"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV56307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="321" mass="35125" checksum="C78597CCB0A6B096" modified="2019-10-16" version="1">MPKRALITGGAGFIGSHLAEKLLAQGMHVTIVDDLSTGRFENIAALEPRDDVQIIIDTVFNESLVADLIQKSDVVYHLASAVGVKLIIDQPVKTIETIVGGTEIVLRHCSRFRRPVLITSTSEVYGKGSKIPFHEEDDLVTGATSRHRWAYACSKTLDEFLALAHHRETQLPVAIVRLFNTVGPRQTGQYGMVVPNFVQSALKGKPLIVHGDGTQSRCFAHVADVVGALVEIMSTPKCYGQVVNIGNDEEVSINQLAQRVVELTGSSSQIEKISYDAAYGDGFEDMQRRVPCLQRAADLIGYKPTRDLEQIIRDVAASFAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITB4</accession>
    <name>A0A518ITB4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_23160</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="50" mass="5832" checksum="1FBAA917CFBA00D6" modified="2019-10-16" version="1">MLTHPLQVCLRDSLRLDPQKICCAPLLDRPWKPNLVPAIRAHPNTYYLIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITG4</accession>
    <name>A0A518ITG4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Ribonuclease HI</fullName>
            <ecNumber evidence="1">3.1.26.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rnhA_1</name>
        <name evidence="1" type="ORF">Mal33_23670</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.26.4" evidence="1"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004523">
        <property type="term" value="F:RNA-DNA hybrid ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="170" mass="19326" checksum="A69388BAC5CD380D" modified="2019-10-16" version="1">MVAALPEYLLVCETRLDEEDRHHWRFSLETILGQSVVEASDHEPCDLNRLALWSVVRGLEALDGPSCVTMMCSNRYVIHGLRNGLNSWRETRFSWDHFGRMVTIPNADLWRRVDRALDIHQVSTCWLSAAFLSQGRNAAQLPESRPAPLDRIRKWLAGQAVADTPTFAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITI4</accession>
    <name>A0A518ITI4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_23830</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="92" mass="10294" checksum="AA4F3F54625A7447" modified="2019-10-16" version="1">MADLFLQHVDPDQFRKDIVADVIEAIAPLLADNREPRLVDRQRMADLLNVSLPHLDCQIRDGLIPSKLIGKRRLFDPAEVIAALPTEGGVEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITM8</accession>
    <name>A0A518ITM8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Amino-acid acetyltransferase</fullName>
            <ecNumber evidence="2">2.3.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">argA</name>
        <name evidence="2" type="ORF">Mal33_24330</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.3.1.1" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004042">
        <property type="term" value="F:acetyl-CoA:L-glutamate N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0103045">
        <property type="term" value="F:methione N-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="137" mass="15699" checksum="32452B46FC4AC625" modified="2019-10-16" version="1">MSTTIREATADDAAVIWEFLEPFFADRLLLRRSEEEVQVLSKHGFVAFEADVCIGFAAVEIYSRKLAEIQCLAVSERFRNQGIGHELVRRCAMRARELGVMEVMAISSSERFLQSCGFDYALPDQKKALFYQLRPRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITS6</accession>
    <name>A0A518ITS6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_24790</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="314" mass="35996" checksum="FF7CA49D7A147DD3" modified="2019-10-16" version="1">MITDIPTADDFAQTGIDYLNLAWDAVADLAFNFEDAKEAFWDDADDIDVDEMTSEYWTAAQRPISTAVSLAHQGGEFLLKSIISRTSPFLLISGNPSSWPADVTVSDTPYSAFRTIDAQDLVRVHDSVASLRLPSDFARRFDELRQKRNSIMHTVDRHLRVEVLDVFRDVLEITHHLIRPLAWVEKRRQFLESCTMSVAYSTEHVDVRMARDFLRLANLLQPAEVAKYFDIDKKQRRYYCWDCQFECCDHYFDAKSAVLRPNTPSSTTVFCFICGNSRTIRRLDCSHPDCKGNVIDTEEGTCLTCFETRDITMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITV8</accession>
    <name>A0A518ITV8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_25120</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="146" mass="15551" checksum="E48E1EA5595D8C6D" modified="2019-10-16" version="1">MGLWGYSTEKLAAEIRRRAFQLPLPRDHSPPVGAPTHGTFVRIPVDGIQGATKGGKKPSVTSCTKYDPIGTDGELEKSLDSAGNPISIDIRHYGAPIAPRAEHEFQYMPVKRFRGGWVLIVEYCNGDGSGAAGAMIGSAVIGTDTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IU12</accession>
    <name>A0A518IU12_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_25700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="747" mass="81599" checksum="0A9B99A91CDA6B72" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IU40</accession>
    <name>A0A518IU40_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sulfotransferase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_25960</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008146">
        <property type="term" value="F:sulfotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000863">
        <property type="entry name" value="Sulfotransferase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00685">
        <property type="entry name" value="Sulfotransfer_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Sulfotransfer_1" evidence="1">
        <location>
            <begin position="13"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="284" mass="33110" checksum="9FFC1DCEF6EB4F16" modified="2019-10-16" version="1">MLRFLKPKPPELFFIRGYAKSGTNWLCNLMNLHPQVRCCGEFHFPTLFRGLLGEQEDLAALLKKNENRPILEDRLHQMIRDLVVDVCGPARLCGDRTPCPLRSLIIPDSKTLYITRDGRDAMVSWTYHSMNLDIEEWPEMKAKVKQVQADPNYFETHKNELLSCEQSVRAFAAQWNAVVCDDFDVMRAADRGEIPLDYHWVRYEDLHRDTLARRDEIYRFLNLKPKQAQPLTAKTEAGFGNGKTNRPHHFYRRGCAGTWQEYFTDEQRNWFESEASEALQLVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IU46</accession>
    <name>A0A518IU46_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Thiol-disulfide oxidoreductase ResA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">resA_4</name>
        <name evidence="3" type="ORF">Mal33_25820</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016209">
        <property type="term" value="F:antioxidant activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021876778" evidence="1">
        <location>
            <begin position="28"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="2">
        <location>
            <begin position="42"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="214" mass="22693" checksum="270457B893BFF113" modified="2019-10-16" version="1" precursor="true">MSLKKLLSLRLSLGLAAILSCSALATADDAAIASDATQTKPLEVGAALPDVAVKSVDGKPVSIASLHKDKPVVLVFFRGGWCPICTRHTQTLIKAYPAIKQLGAELVGISPDDPQHSQANVAKNSIPFPILSDSDLAATKAFGLAFEVDAPTLERYKGFGIDLEKASGFKHHGLPVPAVYIVDKSGKIVFAHSDPNYRERLDTGKVVAALQQLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IU52</accession>
    <name>A0A518IU52_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RNA polymerase sigma factor SigM</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">sigM</name>
        <name evidence="4" type="ORF">Mal33_26050</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014289">
        <property type="entry name" value="RNA_pol_sigma-24-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02943">
        <property type="entry name" value="Sig70_famx1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="2">
        <location>
            <begin position="18"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="3">
        <location>
            <begin position="132"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV56613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="200" mass="23149" checksum="FC6DB101A1841C6B" modified="2019-10-16" version="1">MDNPAEPEGPGLLEPASWVDEHGDFLFRYAVSRLRNAEAAEEVVQQTFLAGLQHVHQFSGKGSERGWLTGILKRKVIDLIRVRQRTENLVDDDGGNPMDQMFDRAGNWKKSVRSTLMQPLDSLEREEFWPILRQCLHRLPANQADAFTLREMEDLGTEEICKELAITPSNLWVLLHRARVRLAQCMKTRWNQDRDQLDTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUD6</accession>
    <name>A0A518IUD6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Outer membrane protein transport protein (OMPP1/FadL/TodX)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Mal33_27030</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell outer membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the OmpP1/FadL family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005017">
        <property type="entry name" value="OMPP1/FadL/TodX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35093">
        <property type="entry name" value="PTHR35093"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03349">
        <property type="entry name" value="Toluene_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021840647" evidence="8">
        <location>
            <begin position="25"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV56705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="439" mass="45563" checksum="2E87BD92BFAB8CCD" modified="2019-10-16" version="1" precursor="true">MRNQITPRILITALACLIAGSSFAQGIVLPGAGPINRSMGGASTAAPIDAAGALLWNPGSITALGSSQMMFGAEFLYTRTTLDSSLPADAFGPAIPAIPIGGSSDSHSGVPVLPTIALVFTEPDSDFAFGLGVFTIGGFGVNYSASATNPLLTPQPPNGFGIGNAYSRLNLLQIAPTVAVQLIDGLSVGFAPTVTMGDLALAPALFAAPDNADGGLPTYSDAQNGRWRYALGFQVGVYLETQSGWNFGASFKSKQWFEEFEFQSAGETGAPRTLTANPEYPMIISLGTSFTGFEGWVSAVDVRYIDYANASVFGDDAAFQADGSVPGLGWDSTVGVAFGLQREFQNGVSLRAGYDFGQSPISNDKTGFNVLSSALWNHAVTTGATLPVNHALSMSLAYVHVFEDSSTGAIQTPAGPIPGSSVEITQVSDTLSMGFDVKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUH0</accession>
    <name>A0A518IUH0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cyclopropane-fatty-acyl-phospholipid synthase</fullName>
            <ecNumber evidence="3">2.1.1.79</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">cfa_1</name>
        <name evidence="3" type="ORF">Mal33_27310</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CFA/CMAS family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.79" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008825">
        <property type="term" value="F:cyclopropane-fatty-acyl-phospholipid synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008610">
        <property type="term" value="P:lipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003333">
        <property type="entry name" value="Mycolic_cyclopropane_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003085">
        <property type="entry name" value="CMAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="active site" evidence="2">
        <location>
            <position position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR003085-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="413" mass="47032" checksum="09F8F78D381BD8F1" modified="2019-10-16" version="1">MSTTATTIPHPAAPSLSWLQRSARGKMLDWLSTADGGVVRFSDSHQQRTLGTAAEDGLQASLNVREPDFYSQLATGGSLGFAESYLRNHWQTDDLTTLLRILYRNDRQASGDTSWIAKLTRHAARYSHQLASNTLRGSRRNIAAHYDLSNEFFDLFLDSTGMYSSAYFAEDSFSLREASEAKLQRICEKLDLQPRDHVLEIGTGWGGFALHAVQNHGVRLTTTTISSAQYQKAGQRFEAAGIADRVELLDSDYRDLVGRYDKLVSIEMIEAVGERFLKTYFERCGSLLKPGGRFVLQGIVMPESRYDAYRQGVDFIQKYIFPGGFLPSVAAMQQAVGQTTDLRLHTVEDLSPHYARTLHAWRQRFMRRLDDVRRLGFDDRFIRMWEYYLCYCEAAFSEQAVRVVQVVWDKPKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUI7</accession>
    <name>A0A518IUI7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Probable cytosol aminopeptidase</fullName>
            <ecNumber evidence="8">3.4.11.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Leucine aminopeptidase</fullName>
            <shortName evidence="8">LAP</shortName>
            <ecNumber evidence="8">3.4.11.10</ecNumber>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Leucyl aminopeptidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 10" type="primary">pepA</name>
        <name evidence="10" type="ORF">Mal33_27510</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>Release of an N-terminal amino acid, Xaa-|-Yaa-, in which Xaa is preferably Leu, but may be other amino acids including Pro although not Arg or Lys, and Yaa may be Pro. Amino acid amides and methyl esters are also readily hydrolyzed, but rates on arylamides are exceedingly low.</text>
            <dbReference type="EC" id="3.4.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 8">
            <text>Release of an N-terminal amino acid, preferentially leucine, but not glutamic or aspartic acids.</text>
            <dbReference type="EC" id="3.4.11.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="8">Binds 2 manganese ions per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the peptidase M17 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.1" evidence="8"/>
    <dbReference type="EC" id="3.4.11.10" evidence="8"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00433">
        <property type="entry name" value="Peptidase_M17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00181">
        <property type="entry name" value="Cytosol_peptidase_M17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011356">
        <property type="entry name" value="Leucine_aapep/pepB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043472">
        <property type="entry name" value="Macro_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000819">
        <property type="entry name" value="Peptidase_M17_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023042">
        <property type="entry name" value="Peptidase_M17_leu_NH2_pept"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008283">
        <property type="entry name" value="Peptidase_M17_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11963">
        <property type="entry name" value="PTHR11963"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00883">
        <property type="entry name" value="Peptidase_M17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02789">
        <property type="entry name" value="Peptidase_M17_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00481">
        <property type="entry name" value="LAMNOPPTDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52949">
        <property type="entry name" value="SSF52949"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00631">
        <property type="entry name" value="CYTOSOL_AP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8 10" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 8" id="KW-0464">Manganese</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 8" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CYTOSOL_AP" evidence="9">
        <location>
            <begin position="331"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="263"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="337"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="251"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="256"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="274"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="333"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS00631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV56752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="483" mass="51209" checksum="7ECBF4BBE4F80ABC" modified="2019-10-16" version="1">MKMAAAKEMLEDCDAIVVGIDDEGNLDQAGQLLDQRLSGWLGRVVARESRPGAPIGVKLFAAPDAGPLESIVVVGTGDPASRNCGQAYRAAASAMRLLADRKRQHVLIGFAEGWDESLARAAVAGAAAGIPGQDLYRAEIGLVEPRRVSWFGVSETIVQAGTAVGEGICITKRLVNEPPNKIYPESFVAEAQRLGRQCGFEVEAWDKEKLEAENCNAILAVSAGSEREPRLAIFRYNGGPADEAPIAIVGKGVTFDSGGLSIKPSDGMKDMKCDMAGAATVLGTMAAISQLKLAKNVVGLVGLAENMISGSSYKLGDVIKTRNGTTVEILNTDAEGRVVLADTLDVAVQQEPSNIVDLATLTGACLVALGIDVAGVMTNDSPWCDQVKQAAELEDEKVWELPMWDFYGEQIKSKVADIKNIGEGRWGGSITAAKFLETFVGDIPWVHIDIAGPAFADSPKEWRDAGGTGVMVRTLVRLLEQAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUQ2</accession>
    <name>A0A518IUQ2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type II secretion system protein G</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">xcpT_6</name>
        <name evidence="2" type="ORF">Mal33_27890</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011453">
        <property type="entry name" value="DUF1559"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07596">
        <property type="entry name" value="SBP_bac_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="298" mass="32302" checksum="FABDE5B5B901F797" modified="2019-10-16" version="1" precursor="true">MSSKDLRSRAGFTLVELLVVIAIIGILVGLLLPAVQSAREAARRMQCSNNMKQIGLALHNYESTYRCFPAGSIQSNFVSGFASILPYLEEGNLYDQYDFSLYYTDAEVAEISKQEISTYLCPSMVMRRELPMPGTTEVGGPCSYLLNEGTASYMSAGADGMFGLNWGGYGYASRHYRHGDITDGTSNTIGVGETTFNYEDYTWSASTAGTNTALVGTPRWGAFRWIVGYPGVAMGTTAYRINDFSNSTKAGYSSQHPGGAQFLVMDGSVHFIAETIDAVPYESLSTKAGGEVVDDVLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUU5</accession>
    <name>A0A518IUU5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TadE-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_28650</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012495">
        <property type="entry name" value="TadE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07811">
        <property type="entry name" value="TadE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="144" mass="15496" checksum="C5776494E03C5069" modified="2019-10-16" version="1">MNNNQSHRRQPIALRSPRSRRGAVAVEFALTAGIAIAFFFASFEFCRVAMIRHTVDNAVYEAARTGIVPGATSNEVRTKANEILATIGITNANVKVTPANISSAATNLTVDITVPIEKNAFGASLFFKGKSVQRALTMARETAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUV0</accession>
    <name>A0A518IUV0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_28510</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="157" mass="18257" checksum="93F82863823C470C" modified="2019-10-16" version="1">MLMRTKVRTLTVNPAFLQEIKESNRELWDTLHAVRQTCDGGGSRAEIAKRLVRLLDQLRDHLSLQFALEESYGYLECPAVVERRISEAAERAQAQHCRLFLQLTDLCELAEELQYRGFVANEVERLIGETEAFDLDLQSHERCEDDLIEIAYFDLKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUX6</accession>
    <name>A0A518IUX6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_28970</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="166" mass="18403" checksum="D9F0F6241A5D5C9C" modified="2019-10-16" version="1">MANVFRIARGGVGHTPRQATYRNLMSELPRDRIIGSRLIEIGHSAFSEPEFVQQGIGPATFRSHYLRLDTGIVLDLFVAELTISDVDTFPMPGETSGLRPSAVLGRRISAIWSDDTSSPLVAFDDGTYLRDANDGFYGNPLHAGHIADDYTPQERAEFIDYWALES</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUZ2</accession>
    <name>A0A518IUZ2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulatory protein FixJ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">fixJ</name>
        <name evidence="3" type="ORF">Mal33_29070</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH luxR-type" evidence="2">
        <location>
            <begin position="142"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="208" mass="23297" checksum="4B56F2ACB5C9BFE8" modified="2019-10-16" version="1">MVQQESSSTRPIVDCLCMPLELADRLRIELQHQNWEMVSHQSPETLLSQPSEQRYGCAVIYNWSDGRESLELIHRLRALKVPTQIVLVVVEAVATIIARAAHDGATDVLQANQPAAELRDAIANAIEIDRAERPRALESLQQRERLESLSEGERDVLRLVLDGLPNKVIAARLDVSQRTVEARRHKLFLKTGTTSIAELVRMVVQLGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVI4</accession>
    <name>A0A518IVI4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein-arginine kinase</fullName>
            <ecNumber evidence="5">2.7.14.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">mcsB</name>
        <name evidence="8" type="ORF">Mal33_30930</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the specific phosphorylation of arginine residues in proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + L-arginyl-[protein] = ADP + H(+) + N(omega)-phospho-L-arginyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:43384"/>
            <dbReference type="Rhea" id="RHEA-COMP:10532"/>
            <dbReference type="Rhea" id="RHEA-COMP:10533"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29965"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83226"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.14.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the ATP:guanido phosphotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5 6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.14.1" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004111">
        <property type="term" value="F:creatine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046314">
        <property type="term" value="P:phosphocreatine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07930">
        <property type="entry name" value="bacterial_phosphagen_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00602">
        <property type="entry name" value="Prot_Arg_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023660">
        <property type="entry name" value="Arg_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000749">
        <property type="entry name" value="ATP-guanido_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022414">
        <property type="entry name" value="ATP-guanido_PTrfase_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11547">
        <property type="entry name" value="PTHR11547"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00217">
        <property type="entry name" value="ATP-gua_Ptrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="SSF55931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51510">
        <property type="entry name" value="PHOSPHAGEN_KINASE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 5 6" id="KW-0418">Kinase</keyword>
    <keyword evidence="2 5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phosphagen kinase C-terminal" evidence="7">
        <location>
            <begin position="25"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5 6">
        <location>
            <begin position="28"/>
            <end position="32"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 6">
        <location>
            <position position="125"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="176"/>
            <end position="180"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 6">
        <location>
            <begin position="207"/>
            <end position="212"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV57092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="361" mass="40784" checksum="B8D12AC40E7E0A94" modified="2019-10-16" version="1">MDPKLDELAGQCGEWLRGTGPESDIVISSRIRLARNLAGFPFIKKCSPEDRQAIERTVRGKMEKLAQWKDVRYLMVDDLSEVDRQFLVERQLISRELADSEGARAVAIDPDEQFSVMINEEDHLRLQVMHSGLSLQEAWQTVNALDDLIEGEITYAFHSKFGYLTACPTNAGTGLRVSVMLHLPALVITRQIDKVFRSLQKISVTVRGLYGEGSQYMGDFYQVSNQITLGRSEEELVQQVSEVIPVLIDYERRARRFLVEESEQDLHDDVSRARGILTTAKKISSEETMHYLSKVRMGINLGLIDDLPITTINKLFIHTQPAHLQKLRGRTLGSADRNVERASYLQRHLSDSGSNGAAELN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVM1</accession>
    <name>A0A518IVM1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Nitrogen regulation protein NR(I)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">glnG_3</name>
        <name evidence="9" type="ORF">Mal33_31310</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002197">
        <property type="entry name" value="HTH_Fis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002078">
        <property type="entry name" value="Sigma_54_int"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025662">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025944">
        <property type="entry name" value="Sigma_54_int_dom_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02954">
        <property type="entry name" value="HTH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00158">
        <property type="entry name" value="Sigma54_activat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01590">
        <property type="entry name" value="HTHFIS"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00675">
        <property type="entry name" value="SIGMA54_INTERACT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00688">
        <property type="entry name" value="SIGMA54_INTERACT_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50045">
        <property type="entry name" value="SIGMA54_INTERACT_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Response regulatory" evidence="8">
        <location>
            <begin position="3"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma-54 factor interaction" evidence="7">
        <location>
            <begin position="142"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="389"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="5">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV57130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="493" mass="54449" checksum="31CC3B2B33F413AD" modified="2019-10-16" version="1">MPKILVIDDDRAILLLATKALEPFAEVTTALTGEEGLEQVKSKSFDVVLLDIQLPDRSGMAIYCEIRAHDRRLPVIFMTADAGSQTTIEAMQLGAFDYIAKPLAVEPLQKLVNKAIEQRKMSSVAVAIAADDKLPDDSSELFIGKSQPMLEVFKSIGRVSKQDVPVLIRGESGTGKELVARALYQYSHRDQGPFLAVNCAALPDNLLESELFGHEKGAFTGAETRRIGKFEQCNGGTLFLDEIGDMAASVQAKVLRVLQEQRFERVGGNKELQTDVRIIAATNRPLEKMVEEGEYREDLLYRLNGVTIDLPPLRQRSSDIPLLVQHFLTQAKHDLNKPDLEGIAPETLSLLNAYRWPGNVRQLRAVIRRCVLDCVMPVIVPDVLPKELTAPSDSNEPAAAEKASGEAATEKADDSGVCGSKLPELVERLLRDKSTDVYAQTIEYLERFVILRVLQETGGNQSQAAEILGITRGKLRDRVITYGIQLYRDVSAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IW10</accession>
    <name>A0A518IW10_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9 10">Protein translocase subunit SecY</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9 13" type="primary">secY</name>
        <name evidence="13" type="ORF">Mal33_32730</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 10">The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 11">Membrane</location>
            <topology evidence="1 11">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9 12">Belongs to the SecY/SEC61-alpha family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0065002">
        <property type="term" value="P:intracellular protein transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043952">
        <property type="term" value="P:protein transport by the Sec complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01465">
        <property type="entry name" value="SecY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026593">
        <property type="entry name" value="SecY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002208">
        <property type="entry name" value="SecY/SEC61-alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030659">
        <property type="entry name" value="SecY_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023201">
        <property type="entry name" value="SecY_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10906">
        <property type="entry name" value="PTHR10906"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00344">
        <property type="entry name" value="SecY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004557">
        <property type="entry name" value="SecY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103491">
        <property type="entry name" value="SSF103491"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00967">
        <property type="entry name" value="3a0501s007"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00755">
        <property type="entry name" value="SECY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00756">
        <property type="entry name" value="SECY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9 11" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9 11" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 9 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="18"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="77"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="117"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="157"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="192"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="233"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="285"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="334"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="388"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="416"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU004349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="QDV57269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="458" mass="50717" checksum="94C1DE6745600309" modified="2019-10-16" version="1">MLEKLRVVFTIPELRNKILLTLGLLAIYRIGFHISLPMMNQNLAPSAGEDTASQFFEKVSLFAASDLRQATIFGLGIMPYISASIIFQLLGSVWAPIEELKKEGEAGRKKINEYTRYLTVVLCLIQSYMYLKFWLMAGGEGEASKVNPNFFADDSNTLYWGWQITAVLIMTCGTIFLMWLGEQIDEYGIGNGISLLIMAGILAQMPGALFDLIQNMKTELVGLSKGTVGIETLIILIVLFVAVVFGVVFITLGQRRIPTQSAKFTRGRRVYGGNRQFLPLRINQAGVMPIIFASSLLMIPGVMLQFLSKSFTPGTMMFSALNGFGSIMSSGTSFVYNMLYVALIFFFCYFWTAITFNPKEMSDQLKDHGTFIPGYRPGKRTADYLEKVMVRITYVGAAFLAIVAIVPTIVYGSLGVSYSIAGFYGGTGLLIAVSVAFDLIQKIDSHLVMRNYRGLLEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IW35</accession>
    <name>A0A518IW35_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative acrylyl-CoA reductase AcuI</fullName>
            <ecNumber evidence="2">1.3.1.84</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">acuI_1</name>
        <name evidence="2" type="ORF">Mal33_33080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.3.1.84" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043957">
        <property type="term" value="F:acryloyl-CoA reductase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014188">
        <property type="entry name" value="Acrylyl-CoA_reductase_AcuI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43677:SF1">
        <property type="entry name" value="PTHR43677:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02823">
        <property type="entry name" value="oxido_YhdH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKS_ER" evidence="1">
        <location>
            <begin position="16"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="333" mass="35544" checksum="27A070A460612071" modified="2019-10-16" version="1">MADTYRCFWVEKDAAGDVQQSIIDRSVADLPSVDSPSVRVAVRWTSLNYKDALAATGHPGIVRHFPHVPGIDVIGEVIDSDDPQFATGQTVIVTGHELGTSRHGGWSQQIRVLASWIVPLPQGLTPREAIILGTAGFTAAQCVQSLQHHGVEPDSGKVVVTGASGGVASIAIQILSRLGYDVVAVSGKPDQHSRLKRWGAAEVIDRNAFIDDSKRPLLSARYAGAVDTVGGTTLETLLRTTAYRGCIAACGLAGGHELQTTVYPFLLRGITLAGIDSAMCPMPQRLEIWNRLASDWKPTELEDLANEISLDDLPAAVDSMLAGKHSGRSIVPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWN2</accession>
    <name>A0A518IWN2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_34970</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="115" mass="12782" checksum="2F4E144E91CD7917" modified="2019-10-16" version="1">MSGWLVVNQSIELTDRTRQQVNSRGLACETAHNWQTAEQRLLGNRYDVIVVDQAVETGDSRDLYQHLADSSERLAGRVIVTGDEPVHAGGEDLGVLRCEARMLADIDDLIRQVGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWY4</accession>
    <name>A0A518IWY4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Multidrug resistance protein MdtE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">mdtE_2</name>
        <name evidence="5" type="ORF">Mal33_35970</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021847325" evidence="3">
        <location>
            <begin position="21"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="domain" description="HlyD_D23" evidence="4">
        <location>
            <begin position="64"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="113"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV57586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="300" mass="32889" checksum="DE60FD6352201844" modified="2019-10-16" version="1" precursor="true">MKPFTLLPLLFAAVWIPAVCQSTVDAVEPTGGAKWDALQYDPSILETRSQLHGIARGKLESEMRFEIPGVVAKVHVRDGEWVEKGEPLLSLQDAVVRAAWKVAQAQASQHGTVEAARLEAELIGRQLNRLQQAFREQASSEFELEEKRSQFAQAQAALTVQQEEANAAGANLELKAAELQKFHLVAPFAGQVVRIDKKQGQPIDPNETALMIVDARRLEIEIFLPIALFGEIAVGRQYAMRADAPVGRSLQATAIYVAPIVDATSGTFRCLFEIDNTDLKLPAGFAVRLNLPRKLASTSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IX01</accession>
    <name>A0A518IX01_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Type II secretion system protein G</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">xcpT_7</name>
        <name evidence="1" type="ORF">Mal33_36270</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011453">
        <property type="entry name" value="DUF1559"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07596">
        <property type="entry name" value="SBP_bac_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="333" mass="35563" checksum="E637ED7BDFC16514" modified="2019-10-16" version="1">MKRIRTGFTLVELLVVIAIIGILVGLLLPAVQAAREAARRMSCSNNMKQIGLALHNYHDTHQAFPYSVSASGAIATGSATPAAGGVLNHRGWMLLLPFIELQNLQDQIDMNLPTGGHNSNGKGLAGPAPGAAGNANDVAVSTVIDAFLCPSDPNPNQYTNTGSTHYSISVGTTSLLGAFTNYDFNSARTYSSAEKWSRTTFETRRMFGHDESSKMRDVTDGTSNSAAVCETLRATIDGESQTWGFTKWVGHGVDLAYGRGINDNECCGWTTPPYAQVPRKSRLGAWSTVGSTHPGGAQVTFADGSVHFISETTDQIVLNRISYISDGQPIGDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IX26</accession>
    <name>A0A518IX26_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Bacterioferritin</fullName>
            <ecNumber evidence="2">1.16.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">bfr</name>
        <name evidence="5" type="ORF">Mal33_36540</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>4 Fe(2+) + 4 H(+) + O2 = 4 Fe(3+) + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:11148"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="EC" id="1.16.3.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bacterioferritin family.</text>
    </comment>
    <dbReference type="EC" id="1.16.3.1" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008199">
        <property type="term" value="F:ferric iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004322">
        <property type="term" value="F:ferroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:cellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006826">
        <property type="term" value="P:iron ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00907">
        <property type="entry name" value="Bacterioferritin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002024">
        <property type="entry name" value="Bacterioferritin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009040">
        <property type="entry name" value="Ferritin-like_diiron"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008331">
        <property type="entry name" value="Ferritin_DPS_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00210">
        <property type="entry name" value="Ferritin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002560">
        <property type="entry name" value="Bacterioferritin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00601">
        <property type="entry name" value="BACFERRITIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50905">
        <property type="entry name" value="FERRITIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0349">Heme</keyword>
    <keyword evidence="2 3" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0409">Iron storage</keyword>
    <keyword evidence="2 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ferritin-like diiron" evidence="4">
        <location>
            <begin position="1"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="17"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="49"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="50"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="126"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR002560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR002560-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV57641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="162" mass="18372" checksum="47CDFD3E60218EDE" modified="2019-10-16" version="1">MTRVETLKNLQTALSMELTATHQYQLHAGVLDDWGMDRLATKMRQEMQEEIGHSDEYLARILFLNGEPELALQKTPVVAHSLKEMFELDLADEREAIGFYSAAAQKAAEEGDLGSRMLFERIAIDEEGHIGWLELQLSLLDRMGEPAYIAKHMSVEGEDENH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXC1</accession>
    <name>A0A518IXC1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">2Fe-2S ferredoxin-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_37410</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="189" mass="20611" checksum="B8CCDC09510E6A3F" modified="2019-10-16" version="1">MPIVTFGGVQIECELGANLRRVLLNAKLPLYHPVARVTNCRGLGVCGTCAVKLRGSASWPTKIEAARLRLPPHTAEAGLRLACKVLVHGDLDVEKFGGVWGQDLNRPVRLGEPRSCPPPCLPVAPKVFEPAVPSIQFRSSRSVIRSLHVASGRRPASPRRHRAAMSEPARVTRAKLVQLVREREPVGTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXH6</accession>
    <name>A0A518IXH6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">D-galactonate dehydratase</fullName>
            <ecNumber evidence="2">4.2.1.6</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">dgoD_1</name>
        <name evidence="2" type="ORF">Mal33_38050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="4.2.1.6" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008869">
        <property type="term" value="F:galactonate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009063">
        <property type="term" value="P:cellular amino acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036849">
        <property type="entry name" value="Enolase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029017">
        <property type="entry name" value="Enolase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029065">
        <property type="entry name" value="Enolase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018110">
        <property type="entry name" value="Mandel_Rmase/mucon_lact_enz_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013342">
        <property type="entry name" value="Mandelate_racemase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034593">
        <property type="entry name" value="Mandelate_racemase_DgoD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013341">
        <property type="entry name" value="Mandelate_racemase_N_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48080">
        <property type="entry name" value="PTHR48080"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13378">
        <property type="entry name" value="MR_MLE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02746">
        <property type="entry name" value="MR_MLE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00922">
        <property type="entry name" value="MR_MLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51604">
        <property type="entry name" value="SSF51604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54826">
        <property type="entry name" value="SSF54826"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00908">
        <property type="entry name" value="MR_MLE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MR_MLE" evidence="1">
        <location>
            <begin position="159"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="404" mass="45078" checksum="57FD2A8290C7CAB3" modified="2019-10-16" version="1">MQITKIETAIPDQIMPGLLLLRIHTSDGIVGCGETYYAPESVASMLHDWMHHHLLGENPLDIERHWRFLYERTTNFGSRGAELRAISAIDLALWDILGQVTKMPVWQLLGGRVQDSIPTYNSCGGPSYGGKTEDSSGHIWPGHGPMGNQGPLNDYWSIVHEPVQLAEELISEGYTALKTWSTDFAAHKTNGPLHVSLMDVEKAVEPFRKIREALGNKIELILDGHGFFQLPMAIRLAQHLREFDLLWAEDLLRVDSIDTLADFRDKAGIPLAVSEMFSGPDDFRLTLEKRAADYVMIDPTWVGGISQTRNITRLAQFYNVPVVMHDCTGPLTLLSGVQVAATSNNVAWQESVRAHVRMLYPKLIDTEVTIEKGRITVPERAGIGAAWQPELFQSGQGQHRITSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXJ4</accession>
    <name>A0A518IXJ4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lactoylglutathione lyase</fullName>
            <ecNumber evidence="2">4.4.1.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">gloA</name>
        <name evidence="2" type="ORF">Mal33_38120</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="4.4.1.5" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004462">
        <property type="term" value="F:lactoylglutathione lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="5"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="124" mass="13840" checksum="46CF808252049C48" modified="2019-10-16" version="1">MKVLQLNHIALHVADVDTSVAFYRDVLQLEPLPRPAFDFPGAWFRLGIDQELHLIGNRDSAVHSASRGNHLALKVDDLDAWESHLQRLGARHNPRQVRPDGGLQVFLPDPDGHWIELLGTSDGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXZ2</accession>
    <name>A0A518IXZ2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_39680</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="194" mass="20882" checksum="D2143D48590751AA" modified="2019-10-16" version="1">MKNIHKLIIGAMLFGGLTTIQFTGTARAANCQCGLCADDCACCTLKVDKVDEKKTAWEVECKQVCIPKVVFPWQKRCNPCANNGARVRTVRVLKKKEYTCPKLEFTWTPKMIGGCGCCRGGNNCCDDGSCGSCDNGGYLLGANDLQPALTPSIPTPAIDNGVLQTAATDAMIERQVPTVHVARPVGLKSLQLNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IY21</accession>
    <name>A0A518IY21_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glycogen debranching enzyme</fullName>
            <ecNumber evidence="5">3.2.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">glgX</name>
        <name evidence="5" type="ORF">Mal33_40010</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 13 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004133">
        <property type="term" value="F:glycogen debranching enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005980">
        <property type="term" value="P:glycogen catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02856">
        <property type="entry name" value="E_set_GDE_Isoamylase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044505">
        <property type="entry name" value="GlgX_Isoamylase_N_E_set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="Glyco_hydro_13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004193">
        <property type="entry name" value="Glyco_hydro_13_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011837">
        <property type="entry name" value="Glycogen_debranch_GlgX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02922">
        <property type="entry name" value="CBM_48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="SSF81296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02100">
        <property type="entry name" value="glgX_debranch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aamy" evidence="4">
        <location>
            <begin position="155"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="460"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="460"/>
            <end position="475"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV57985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="696" mass="78680" checksum="EEB0F28B8843A4C5" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IY93</accession>
    <name>A0A518IY93_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lipopolysaccharide heptosyltransferase 1</fullName>
            <ecNumber evidence="2">2.-.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rfaC</name>
        <name evidence="2" type="ORF">Mal33_40720</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.-.-.-" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03789">
        <property type="entry name" value="GT9_LPS_heptosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002201">
        <property type="entry name" value="Glyco_trans_9"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01075">
        <property type="entry name" value="Glyco_transf_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="345" mass="37888" checksum="DF27FBC4B555D336" modified="2019-10-16" version="1">MSDKPYNLLITRLSAIGDCIATLPMAAAIKAAMPNARITWAVSCAARQLLEICPDVDRVISVPKRYLRTPSDLMAMRRQLREQPLDCVLDPQSLTKSAALGWMSNAPLRIGFAKPRGRELAPWMNTVSVDSDPELHVIDAQAELLRPLDIVPGKPQFNLNIPDDVSQWAQQHVMESVGDPNPVIMNPGAGWDSKMWPAERFGQVAAWLRNEHKIPTLIVWAGQRERELAEQIRQVSGDTAVLAADTSLVQLAAVLKQAKLFLSSDTGPMHLAVAVGTRCVTLHGPTRPELSGPYGPEHLSIQKARFDGTSRQRRSADNWSMRAIEVVDVCAGLTQMLSRSSRAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYF4</accession>
    <name>A0A518IYF4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Chemotaxis protein CheY</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">cheY_4</name>
        <name evidence="3" type="ORF">Mal33_41290</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="3"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="128" mass="13986" checksum="852EB8B878FC729C" modified="2019-10-16" version="1">MISVLVVDDSKFMAKVLQTVLTDIGFDVVGLGSDGDEGVKLFKELSPDVTLLDVTMPNMDGLECLTEIRAHSPEANVIMLSALKDEEIVRKCLEAGAGAFLEKPIRRHCTEDQQRLISAVEKTMGHTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYJ3</accession>
    <name>A0A518IYJ3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_41610</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="112"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="144" mass="15563" checksum="92BCF28B1CA2F054" modified="2019-10-16" version="1">MRIVLAIHAALILLASTAFTIITAPLGGNSLHWSFYSYSFRSGFGTPHVANYSTAVALTYLIAFVFGGIGFTMASRRGRIRTGMLGIILSVIGFVSFTVELSHVFVDHHRSWIVIAPVAMLVLALIACLPQRDAILRDVKAASV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYN4</accession>
    <name>A0A518IYN4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_42160</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="165" mass="19046" checksum="44431563688DBCE6" modified="2019-10-16" version="1">MDENQQPAQRWVEIEFDCLPLRTVQRLDVPLDASPRFEAFVLRVKQAIQEHGVMNTYYLHNARCTFHFTNDPNRGMVQFKFEGTVFTDSTDTSTISCHLDVQPDGETCDWLNEAVVRWLAESVRHALVVEFDRYIQAGDLSKTQQRLEQIQAESDAAEGFLGMYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYU2</accession>
    <name>A0A518IYU2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidyl-prolyl cis-trans isomerase</fullName>
            <ecNumber evidence="4">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Mal33_42660</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 3 4">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the FKBP-type PPIase family.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0697">Rotamase</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021737720" description="Peptidyl-prolyl cis-trans isomerase" evidence="5">
        <location>
            <begin position="31"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase FKBP-type" evidence="6">
        <location>
            <begin position="70"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV58248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="156" mass="16643" checksum="97E3E8C80B17F12C" modified="2019-10-16" version="1" precursor="true">MNYQTTARQACRVPFCLTAALMILTCVACAGPSSGPGPRDPDAPTDFTKTESGLKYRILRAGDGAKPVTTDEVTVHYRGWLDDQTIFDSSYKRGAPATFRLDQVVPGWTEGLQLVDEGGMIELTIPSHLGYGEAGAGGTIPGGATLHFIVELIKIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYZ7</accession>
    <name>A0A518IYZ7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_43310</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010869">
        <property type="entry name" value="DUF1501"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07394">
        <property type="entry name" value="DUF1501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="469" mass="51576" checksum="1157FC056D6FEEE1" modified="2019-10-16" version="1">MNFSRRQLLKTTGAGFGSLALASLLAEESQGSNLPGLSGSERAPHFAPRARRVIFLFMKGGPSHMDTFDYKPQLQKDDGKPLPFEKPRVQFAPTGNLLGSPWKFKRYGESGIAVSELFPHVAECVDDLCIINSMYGSNSAHGGACLKIHTGSDVFVRPSMGSWISYGLGTENQNLPGFITICPTLAHGGTKNWSSAFLPASHTGIPLGNASQPSDQARVKYMQNANLDRASQRMQLELMQSMNQNFLDSTGPDSALEARIKSFELAFRMQTEMPDALDLAAETKPTHDLYGLDDPKTADFGRQCLMARRFVERGVRFVQVTHSNTEVQWDQHGSLRKGHEQNAKEVDKPIAGLLRDLKARGLLKDTLVLWGGEFGRTPTCQGSGNDGRDHNPEGFTMWMAGAGVRPGIQYGATDDYGYYATVDKVHVHDLHATLLHLMGLDHTRLTYRHAGRDFRLTDVAGKVVKGILT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ10</accession>
    <name>A0A518IZ10_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF5615 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_43430</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041049">
        <property type="entry name" value="DUF5615"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18480">
        <property type="entry name" value="DUF5615"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF5615" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="67" mass="7212" checksum="926BA5E43179CB20" modified="2019-10-16" version="1">MKFLLDQGLPRSTVDYLRDSGVESEHVGALGVATASDEILSVGRDRGAVVGLHSIPTSTRSWLSRML</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZJ9</accession>
    <name>A0A518IZJ9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Amino_oxidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_45340</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amino_oxidase" evidence="1">
        <location>
            <begin position="18"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="450" mass="50512" checksum="2D36E7502EB86E94" modified="2019-10-16" version="1">MSENDPGKSKWLVVGGGMAGLTLAHRLSQRGQEVSVCEAAPSFGGLTSACSLGDIVWDRFYHVTLLSDSHLRGLLKELDLEHEIRWVTTKTGFFSGGRLYSMSNSWEFLNFPPLTLIEKLQLGGTIFYTSKLRNWRRLEQIHVADFLKRLSGKGTFEKIWLPLLRAKLGETYQKASAAFIWSYISRMYKARRSGIKTEMFGYVPGGYARIIDRFVETLRGNGVRLLSSHGVQSITQCEAGGLNVDFGDGRIERFDNVISTIPSPIISQHCPELTEDEHQRLQGVEYIGVVCASMLLSESISPYYVTNITDDWVPLTAVIEMSTIVDREELGGHALVYLPKYLPDSDPGLQESDAEIQERFLSTLEKMYSHFSRDQVQAFQISRAKHVMALPTIDYSQKLPPIVTSLPGFYALNGAHITKGNLNVNETIDLADEKLNDLVWPDFLSRCGSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZW0</accession>
    <name>A0A518IZW0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Beta_helix domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_46460</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039448">
        <property type="entry name" value="Beta_helix"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006626">
        <property type="entry name" value="PbH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13229">
        <property type="entry name" value="Beta_helix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00710">
        <property type="entry name" value="PbH1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021726758" description="Beta_helix domain-containing protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="domain" description="Beta_helix" evidence="2">
        <location>
            <begin position="144"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="659" mass="71321" checksum="699C729A8F73F694" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZY7</accession>
    <name>A0A518IZY7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Bifunctional purine biosynthesis protein PurH</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="8">Phosphoribosylaminoimidazolecarboxamide formyltransferase</fullName>
                <ecNumber evidence="8">2.1.2.3</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="8">AICAR transformylase</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="8">IMP cyclohydrolase</fullName>
                <ecNumber evidence="8">3.5.4.10</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="8">ATIC</fullName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="8">IMP synthase</fullName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="8">Inosinicase</fullName>
            </alternativeName>
        </domain>
    </protein>
    <gene>
        <name evidence="8 10" type="primary">purH</name>
        <name evidence="10" type="ORF">Mal33_46800</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>(6S)-10-formyltetrahydrofolate + 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide = (6S)-5,6,7,8-tetrahydrofolate + 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide</text>
            <dbReference type="Rhea" id="RHEA:22192"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:57454"/>
            <dbReference type="ChEBI" id="CHEBI:58467"/>
            <dbReference type="ChEBI" id="CHEBI:58475"/>
            <dbReference type="EC" id="2.1.2.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>H2O + IMP = 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide</text>
            <dbReference type="Rhea" id="RHEA:18445"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="ChEBI" id="CHEBI:58467"/>
            <dbReference type="EC" id="3.5.4.10"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Purine metabolism; IMP biosynthesis via de novo pathway; 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide (10-formyl THF route): step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Purine metabolism; IMP biosynthesis via de novo pathway; IMP from 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide: step 1/1.</text>
    </comment>
    <comment type="domain">
        <text evidence="8">The IMP cyclohydrolase activity resides in the N-terminal region.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the PurH family.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.3" evidence="8"/>
    <dbReference type="EC" id="3.5.4.10" evidence="8"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00133"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003937">
        <property type="term" value="F:IMP cyclohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004643">
        <property type="term" value="F:phosphoribosylaminoimidazolecarboxamide formyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00139">
        <property type="entry name" value="PurH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024051">
        <property type="entry name" value="AICAR_Tfase_dup_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011607">
        <property type="entry name" value="MGS-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036914">
        <property type="entry name" value="MGS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002695">
        <property type="entry name" value="PurH-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11692">
        <property type="entry name" value="PTHR11692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01808">
        <property type="entry name" value="AICARFT_IMPCHas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02142">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000414">
        <property type="entry name" value="AICARFT_IMPCHas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00798">
        <property type="entry name" value="AICARFT_IMPCHas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00851">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52335">
        <property type="entry name" value="SSF52335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="SSF53927"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00355">
        <property type="entry name" value="purH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51855">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 8" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="5 8" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MGS-like" evidence="9">
        <location>
            <begin position="2"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV58656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="523" mass="56262" checksum="6E9F1273EDB80029" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J083</accession>
    <name>A0A518J083_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative transcriptional regulatory protein pdtaR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">pdtaR_1</name>
        <name evidence="3" type="ORF">Mal33_47740</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="6"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="120" mass="13374" checksum="3D46C42014D1C0EC" modified="2019-10-16" version="1">MTKVLRIVVADDEPEIRDYFRRILPRFGYEVVGIAENGRELVDLCQQKQPDLVITDIMMSELCGLDAIAEIRKTQHVPVIVVSSNDKPKSDSCGCVDEFLVKPIRSSDLQAAIARVQSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0E4</accession>
    <name>A0A518J0E4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_48380</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="646"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="431"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="653"/>
            <end position="668"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="869" mass="94563" checksum="411D57446AA557CB" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0F3</accession>
    <name>A0A518J0F3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">N-acetyl-gamma-glutamyl-phosphate reductase</fullName>
            <shortName evidence="4">AGPR</shortName>
            <ecNumber evidence="4">1.2.1.38</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">N-acetyl-glutamate semialdehyde dehydrogenase</fullName>
            <shortName evidence="4">NAGSA dehydrogenase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4 7" type="primary">argC</name>
        <name evidence="7" type="ORF">Mal33_48100</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>N-acetyl-L-glutamate 5-semialdehyde + NADP(+) + phosphate = H(+) + N-acetyl-L-glutamyl 5-phosphate + NADPH</text>
            <dbReference type="Rhea" id="RHEA:21588"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29123"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57936"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.2.1.38"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 3/4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.38" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00108"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003942">
        <property type="term" value="F:N-acetyl-gamma-glutamyl-phosphate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00150">
        <property type="entry name" value="ArgC_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023013">
        <property type="entry name" value="AGPR_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000706">
        <property type="entry name" value="AGPR_type-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000534">
        <property type="entry name" value="Semialdehyde_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012280">
        <property type="entry name" value="Semialdhyde_DH_dimer_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01118">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02774">
        <property type="entry name" value="Semialdhyde_dhC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00859">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01850">
        <property type="entry name" value="argC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01224">
        <property type="entry name" value="ARGC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4" id="KW-0521">NADP</keyword>
    <keyword evidence="3 4 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Semialdhyde_dh" evidence="6">
        <location>
            <begin position="4"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="active site" evidence="4 5">
        <location>
            <position position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV58785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="336" mass="36565" checksum="D7EFDB6F523D83E0" modified="2019-10-16" version="1">MKVRVGIIGATGYTAYEAIRLLLRHPHAEVTAVTSRQDEGLSIAAVHPQLTSRLDLPLQPLDIDSFAQQCDVAFCCLPHGASAETVKQLRQANCKVIDFSADFRLTSVAEYETWYGVKHPWPEQVGQVAYGLPELFADQIKDADLIANPGCYPTSAIMPLAPLIQAGAIHCEDIIVDSKSGVSGAGRSPKLGTLYCETNESIAPYAIGAHRHQPEMNDIIGRFSGSKTNILFTPHLTPMDRGILSTIYVRPQAADAKRVREIWRQTYRDSPFVRVVDHIPGTKHVAGTNFVDLAVKEAGDRLVLVAAIDNLIKGASGAAVQNLNCIFGWDQTLGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J146</accession>
    <name>A0A518J146_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Pentapeptide repeats (8 copies)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_50770</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001646">
        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00805">
        <property type="entry name" value="Pentapeptide"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13599">
        <property type="entry name" value="Pentapeptide_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="115" mass="12883" checksum="3DF05FA41C6766E5" modified="2019-10-16" version="1">MHSSITMQNSADNMDVVAQDQTFTDCIAEGSHFEGATLTRVTFTRCDLYWASFFMALLADVTFDQCDLRGSDFKDATMRYCRFLNCDIGTDAIGGQTEFGDNDLSTVQFINCRGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1D2</accession>
    <name>A0A518J1D2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_51740</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="72" mass="7878" checksum="07408E3D59C703F1" modified="2019-10-16" version="1">MGSKLFSQTPPLPTPNLVYAGTVSRLIHASDDVTTPSLPFFNSQPHFAHSEYLRNTFISSSIFSSRSLALPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1J6</accession>
    <name>A0A518J1J6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Holo-[acyl-carrier-protein] synthase</fullName>
            <shortName evidence="8">Holo-ACP synthase</shortName>
            <ecNumber evidence="8">2.7.8.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">4'-phosphopantetheinyl transferase AcpS</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 10" type="primary">acpS</name>
        <name evidence="10" type="ORF">Mal33_52280</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>apo-[ACP] + CoA = adenosine 3',5'-bisphosphate + H(+) + holo-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:12068"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:9690"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:58343"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="EC" id="2.7.8.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the P-Pant transferase superfamily. AcpS family.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.7" evidence="8"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008897">
        <property type="term" value="F:holo-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00101">
        <property type="entry name" value="AcpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008278">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037143">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002582">
        <property type="entry name" value="ACPS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004568">
        <property type="entry name" value="Ppantetheine-prot_Trfase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01648">
        <property type="entry name" value="ACPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56214">
        <property type="entry name" value="SSF56214"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00516">
        <property type="entry name" value="acpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00556">
        <property type="entry name" value="pantethn_trn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 8" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="4 8" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="1 8" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6 8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ACPS" evidence="9">
        <location>
            <begin position="5"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="9"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV59200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="127" mass="14109" checksum="6D4503FC26A52829" modified="2019-10-16" version="1">MNVLGIGTDIVECERIEKMIQKHGELFLNRVYTSGEIQYCSERKAATEHYAGRWAAKEAVLKALGTGWSRGIRWTDIEVRNEPGGKPRIALAGEARKLCEELRLNEVQISISHCRSHATAFAIAVGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1W9</accession>
    <name>A0A518J1W9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_53560</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="87"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="125"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="153"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="179"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="224"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="364"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="448"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="457"/>
            <end position="484"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV59328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="484" mass="54153" checksum="DE671606C91F7AD6" modified="2019-10-16" version="1">MHFDSKLALAWLALGGLGYFQVFPNIILCSIALLATLACMIKRIDDYVPYAEITALIATLQWVFMPMLGYIFETPIQKYRMYVGEEFYFSFALPAVCCMNAMLLSIRRLKDPVGRAFRLEYSPKVLRHVAMLLITAGLASALVSGRVPGSLGFVFHLLSQLTYVAVLILVYHEVPRSRWMLVLAVAPLILGAGRTAMFHSLLLWCCFFGIFWLRSRPRSHAFKMQFIAIGIAGVLAVQFFKGAYREELMSQRGSGRLEAMVSVVSLDLFTREESWMNGVVRFNQGWIISAILDNVPSREPYANGATLQDAIVAAIFPRFIMSTKKAVGGGANFRRYTGLPIGKGTSMGISPLGEAWANFGKEGGIALMFCWGAILSLFIIYLNRLAASRPMFHFLIPLILYQGIKAETEFLVIFNQLTKGLMLSLIVYWGMKHYGNISFLKSEGTLRNPHPPSDATRTHQSTEHSKVAKAVDSRHETSDQKRRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J269</accession>
    <name>A0A518J269_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_54620</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="61" mass="6771" checksum="A8D78F2DF5E27794" modified="2019-10-16" version="1">MYDVWCHAAQQLAANRKGVELEFRSGASERARGTFCSALLAISKPRLRGARGRLSRCGAYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J2E9</accession>
    <name>A0A518J2E9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">3-oxoacyl-[acyl-carrier-protein] synthase 2</fullName>
            <ecNumber evidence="3 10">2.3.1.179</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">fabF_7</name>
        <name evidence="14" type="ORF">Mal33_55530</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>(9Z)-hexadecenoyl-[ACP] + H(+) + malonyl-[ACP] = 3-oxo-(11Z)-octadecenoyl-[ACP] + CO2 + holo-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:55040"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10800"/>
            <dbReference type="Rhea" id="RHEA-COMP:14074"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="ChEBI" id="CHEBI:83989"/>
            <dbReference type="ChEBI" id="CHEBI:138538"/>
            <dbReference type="EC" id="2.3.1.179"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a fatty acyl-[ACP] + H(+) + malonyl-[ACP] = a 3-oxoacyl-[ACP] + CO2 + holo-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:22836"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:9916"/>
            <dbReference type="Rhea" id="RHEA-COMP:14125"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="ChEBI" id="CHEBI:78776"/>
            <dbReference type="ChEBI" id="CHEBI:138651"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 10">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10 12">Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.179" evidence="3 10"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00834">
        <property type="entry name" value="KAS_I_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017568">
        <property type="entry name" value="3-oxoacyl-ACP_synth-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000794">
        <property type="entry name" value="Beta-ketoacyl_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11712">
        <property type="entry name" value="PTHR11712"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000447">
        <property type="entry name" value="KAS_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10 14" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="8 10" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="5 10" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 12 14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PKS_KS" evidence="13">
        <location>
            <begin position="5"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR000447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000447-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="QDV59518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="427" mass="45600" checksum="A0D507FC30227DAF" modified="2019-10-16" version="1">MRPRVVVTGIGMINPMGHDPTTVWKGLQEGQSGVGYTTLFNAKGFPTQISAEVKGWDITDTGEDPELWKHRGRHTKFAAGAAKQAISESGIMDAGVAPHRFGVYLGSGEGNQDFVTFTDMMTVAMEGGEYDMAKFLQKGLEVLNPLVELEQEPNMPAAHLAAMFNAQGPNYNCLTACAASSQAIGEATEIIRRGDADVMLSGGTHSMIHPFGVTGFNLLTALSENNANPTAASRPFDARRDGFVLGEGSGMVVLEELEHARRRGAPIYGEILGYGTTADAFRITDIPPDGHGGIASMRMAISDAGLNPEDIDYVNAHGTSTTVNDKVETLACKQVFGDNAYKTPVSSTKSMMGHLIAAAGVTEMIVCLLAIRDSVLPPTINYENPDPLCDLDYVPNEARQAKVKYALNNSFGFGGQNVTLCLGKFEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J2F5</accession>
    <name>A0A518J2F5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Arylsulfatase</fullName>
            <ecNumber evidence="6">3.1.6.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">atsA_40</name>
        <name evidence="6" type="ORF">Mal33_55460</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="PTM">
        <text evidence="3">The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the sulfatase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.6.1" evidence="6"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004065">
        <property type="term" value="F:arylsulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024607">
        <property type="entry name" value="Sulfatase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00523">
        <property type="entry name" value="SULFATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
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        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021875127" evidence="4">
        <location>
            <begin position="21"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase" evidence="5">
        <location>
            <begin position="106"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="modified residue" description="3-oxoalanine (Cys)" evidence="3">
        <location>
            <position position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR600917-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV59511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="863" mass="94866" checksum="724109901828BC3D" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IM52</accession>
    <name>A0A518IM52_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_01000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="QDV54154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="32" mass="3319" checksum="7ACDEEE017E4417C" modified="2019-10-16" version="1">MEGSLQRAGSGGCKVTKSATETAFRHSPITPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IM87</accession>
    <name>A0A518IM87_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SHD1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_01340</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008092">
        <property type="term" value="F:cytoskeletal protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007131">
        <property type="entry name" value="SHD1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03983">
        <property type="entry name" value="SHD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SHD1" evidence="2">
        <location>
            <begin position="200"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="266" mass="30384" checksum="3CC5C0C9C4838077" modified="2019-10-16" version="1">MGRVKEGQHGGGDRSISCDSRRRVRGWICRSALAFVFLIGGLSTCDAHSGGLDSNGGHRDSKNGGYHFHSHSPQAYVPTQNIVPAMMYRTPSYRTTARSSASIRYRSHARTRAKADGMYEDQDDSDSRAESRPSESSKIRRLQEMREPGREVKYLFHHVRLHPYEVSEFEENGVFWKVSLASGYNVNLRKSDIVRIDSVDPMDFRTWVDASGRFSTIAKYVDLQSRTLQLDRHSESGRLRIPLNRISKFDQAHVHKIKLIQTDKNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IM88</accession>
    <name>A0A518IM88_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Serine/threonine-protein kinase PknD</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">pknD_1</name>
        <name evidence="3" type="ORF">Mal33_01430</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="177"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="816" mass="89063" checksum="0FB34B3FC6A57A5D" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IM94</accession>
    <name>A0A518IM94_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_01580</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="79" mass="8653" checksum="800C3EA9E4F51F39" modified="2019-10-16" version="1">MSTGNRTQQRNASSSEVHRQVEAATHSAAESIQEYGSHYVAEPAKDIFGLLSDYAKDRPDVMAVWSFGLGVVVGWKLRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMC9</accession>
    <name>A0A518IMC9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Outer membrane efflux protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_02000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021703718" evidence="3">
        <location>
            <begin position="29"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="35"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="461"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="602"/>
            <end position="629"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV54250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="783" mass="86607" checksum="0BA92D0365FD8E40" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMD4</accession>
    <name>A0A518IMD4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_01970</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013196">
        <property type="entry name" value="HTH_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028349">
        <property type="entry name" value="PafC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026881">
        <property type="entry name" value="WYL_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08279">
        <property type="entry name" value="HTH_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13280">
        <property type="entry name" value="WYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016838">
        <property type="entry name" value="PafC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_11" evidence="1">
        <location>
            <begin position="24"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="domain" description="WYL" evidence="2">
        <location>
            <begin position="143"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="328" mass="36837" checksum="018FE1BD361D42E0" modified="2019-10-16" version="1">MATRSERHPRLLLLIANGEGKQGVESLAAALRVSSKTVRRDIASLRDVGVAIQEQIGDNGQKCYWLSKESLPQIKFAYDEALAMMLCRSGIRAFDGTPLGEASETAFEKITQAIGPMERRFLERMLPRIHIAQVGSDYAAHGEILDALTLGIEENRATFITYRSNRSTEPVTYDIFPYAMAEHRGSLYVVGWHNDEELVKTWKVDRMSDAEVTEIRFERPADFNAQEHFRGAFAIVTGDESITVRVRFTGTAARYVQEKRMHPTQQVEVLGQSLAEVTFELTSTMEIKSWVLSFGASAEVLEPQELRDEIQAELAAATNLYASEQIEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IME6</accession>
    <name>A0A518IME6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FHA domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_02040</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd00060">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032030">
        <property type="entry name" value="YscD_cytoplasmic_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16697">
        <property type="entry name" value="Yop-YscD_cpl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SSF49879"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="2">
        <location>
            <begin position="24"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="156"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="229" mass="25259" checksum="498F4DBDBA2E9ADB" modified="2019-10-16" version="1">MQVKLKVLSGSHAGREISVSQEKFLIGRNDQCQLRPKSESVSRKHCILVQRDGKLLIQDLKSRNGTFVNGKRLPPDRAKALKPGDALTVGKLEFEVLVEYGLGGAKKPEVVDVKDAAQRTVNASGDDSKFEEVDINSWLDEADNIERVRKLGEPETRQMNIDASKTIEGDEELSGELSVGDGDSKDESGKRKPPEKKPPQKLPSSMKKQMSENSRDAAGEALKKFFSGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMJ7</accession>
    <name>A0A518IMJ7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Outer membrane biogenesis protein BamB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_02730</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018391">
        <property type="entry name" value="PQQ_beta_propeller_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002372">
        <property type="entry name" value="PQQ_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13360">
        <property type="entry name" value="PQQ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00564">
        <property type="entry name" value="PQQ"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022055684" evidence="1">
        <location>
            <begin position="20"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="441" mass="48132" checksum="EE9C5CBF539FED05" modified="2019-10-16" version="1" precursor="true">MRSLLTLCLALAAAIPTQADWPQWMGENRDGNVSGTGWIKSIPAEGLKTVWRMPIKGGYAGPSVADGRVYVTDYVRTSGEAVNDPGARATLGGQERVLCFDAKTGKKIWEHAYDCPYSISYPAGPRCTPTVDGDRVYALGAEGDLWCLSTADGSVIWQRSFKKDFNSAVPIWGHAAHPLVDGDQLICMVGGETQSVVSLDKMTGKEIWKRPTVGNDIGYCPPRIIQAGGTRQLITFSPKGIESLDPKTGKPFWDVPLTPLYGMSITMPQHDGNLMFASGIGSESVMLELGSDQPTVKELWRGEQKTSIYCANSTPMIVDGVIYGSDCQVGHFAAIDTKTSDRLWTTFAPTTGGERRAKHGTAFVTKYGDQFFLFSETGDLIIAAIDSKEYNEIGRFHVLEPTGECFGRSVVWSHPAYSGKHLFARNDEEIVCVSLDADDYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMM7</accession>
    <name>A0A518IMM7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_02870</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
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                <person name="Peeters S.H."/>
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                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
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                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
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                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
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        </source>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
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                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
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                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
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                <person name="Galperin M.Y."/>
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            <strain evidence="6 7">Mal33</strain>
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    <sequence length="587" mass="62862" checksum="3570D45FA216A5BF" modified="2019-10-16" version="1"> </sequence>
</entry>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PLAT" evidence="2">
        <location>
            <begin position="228"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00024035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="266" mass="28169" checksum="B5BB32DE7324CC18" modified="2019-10-16" version="1">MSIITLLTDFGVSSPYVAQIKGVLATRQPESHVIDLTHSVPPQNVQTAAITLDDLAPWFPSGAVHVAVVDPGVGSDRRILAAHVGDWYFVLPDNGLISPLADRFAVKSVVALDRPEFWLSPVSNTFHGRDVMAPVAAAIARGVPLEELGGSVGDWHRVHIPRPCVMSKSIQGEVIYVDSFGNLITNISADDVHGDDVFRIGDRAVNGLVRSYSDRTAGQLVALIGSSGRLEFAVVDGNAAVQFGAGQGASVEVDLVGETQQVGDSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IN48</accession>
    <name>A0A518IN48_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">YacP-like NYN domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_04620</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010298">
        <property type="entry name" value="DUF901"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34547">
        <property type="entry name" value="PTHR34547"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05991">
        <property type="entry name" value="NYN_YacP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="185"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="191"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="233"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="266" mass="29847" checksum="2F32D50A3626E718" modified="2019-10-16" version="1">MRLLIDGYNLLHQSDLMGTGHGAAWLERARQRLIDTIAAYLEPQDLPQTTIVFDRHSGKQIDAHQVDSSGIQIFYAVDHPEADDLIEDLIAKSSHPKQLTVVSSDHRLQKAIDRRGGKSVDADIWYERLLAGQVTTGAKKNKQGRGNRQAKRGKSHKPDSPLTDEQLARWLDRFNADAIQDELSSLAEEPSPIPKPCPPALPQPKAKPAKKATKQKPQPKPPKKPSAPRSKKKQPATKPEDLSKRKLQQENYNPFPEGYTDDLWDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IN53</accession>
    <name>A0A518IN53_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_04700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="131" mass="14829" checksum="C617BE10105F451B" modified="2019-10-16" version="1">MYPDNWELTGPVDDGDSEGYVVESPTGMFFSLNRYAGRSDHENILKQACQAMDAEYDEVESEVYKSEGAFPEEVGVELQFYCNSLVITSLMLAMQYQDDVLLVQMQAENRDFDQNELVFAAMLKTVRDGLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IN91</accession>
    <name>A0A518IN91_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_05010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="397" mass="44233" checksum="8BFD26CE29923D1D" modified="2019-10-16" version="1">MLQPRSSWGASSAAREDQPYAQIDWDRCRRIGSVTHAHCRSQRSLDLLCRRGLTHLAISNYYPSAPCSPTEQIGQWKVGQDFCTLKGEGYVEREFAWNEIIRDPETGWFDELPTAMQEKMPFQSEKPCFTQILPEVILCPNAEHHSMTDCNGHFNAVGSNFASGTFDVRSYYKLNNHGYAMGAGMPWREAFGRMLDGLQFADGGGITINHPKWSHTSPKQIMEFLDFDPRVMGIEIWNSTAEFLSQTGWSLDEWDAVLATGRRCYGFSVSDHAHNSDPAFQGRNVLLVDAATPASEMPAACLRAYRNGNFYASLDGVLELKRFQCSADGKLDVQISGGPSKLRVVSAKGVVHEQAGEAISWALPEGKSSAQEHVYLRVEADQVDGEDRLLTQAIQLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INB7</accession>
    <name>A0A518INB7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Bifunctional uridylyltransferase/uridylyl-removing enzyme</fullName>
            <shortName evidence="2">UTase/UR</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Bifunctional [protein-PII] modification enzyme</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">Bifunctional nitrogen sensor protein</fullName>
        </alternativeName>
        <domain>
            <recommendedName>
                <fullName evidence="2">[Protein-PII] uridylyltransferase</fullName>
                <shortName evidence="2">PII uridylyltransferase</shortName>
                <shortName evidence="2">UTase</shortName>
                <ecNumber evidence="2">2.7.7.59</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="2">[Protein-PII]-UMP uridylyl-removing enzyme</fullName>
                <shortName evidence="2">UR</shortName>
                <ecNumber evidence="2">3.1.4.-</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="2 5" type="primary">glnD</name>
        <name evidence="5" type="ORF">Mal33_05310</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>[protein-PII]-L-tyrosine + UTP = [protein-PII]-uridylyl-L-tyrosine + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:13673"/>
            <dbReference type="Rhea" id="RHEA-COMP:12147"/>
            <dbReference type="Rhea" id="RHEA-COMP:12148"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:90602"/>
            <dbReference type="EC" id="2.7.7.59"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>[protein-PII]-uridylyl-L-tyrosine + H2O = [protein-PII]-L-tyrosine + H(+) + UMP</text>
            <dbReference type="Rhea" id="RHEA:48600"/>
            <dbReference type="Rhea" id="RHEA-COMP:12147"/>
            <dbReference type="Rhea" id="RHEA-COMP:12148"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:90602"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="2">Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.</text>
    </comment>
    <comment type="domain">
        <text evidence="2">Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GlnD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.59" evidence="2"/>
    <dbReference type="EC" id="3.1.4.-" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008773">
        <property type="term" value="F:[protein-PII] uridylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006808">
        <property type="term" value="P:regulation of nitrogen utilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00277">
        <property type="entry name" value="PII_uridylyl_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013546">
        <property type="entry name" value="PII_UdlTrfase/GS_AdlTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010043">
        <property type="entry name" value="UTase/UR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47320">
        <property type="entry name" value="PTHR47320"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08335">
        <property type="entry name" value="GlnD_UR_UTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006288">
        <property type="entry name" value="PII_uridyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01693">
        <property type="entry name" value="UTase_glnD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51831">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="2 5" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HD" evidence="4">
        <location>
            <begin position="454"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="domain" description="ACT" evidence="3">
        <location>
            <begin position="806"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="region of interest" description="Uridylyltransferase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV54576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="880" mass="100993" checksum="F4074422E15A4016" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INK5</accession>
    <name>A0A518INK5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycerophosphoryl diester phosphodiesterase</fullName>
            <ecNumber evidence="3">3.1.4.46</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ugpQ_2</name>
        <name evidence="3" type="ORF">Mal33_06220</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.4.46" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008889">
        <property type="term" value="F:glycerophosphodiester phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018476">
        <property type="entry name" value="GlyceroP-diester-Pdiesterase_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030395">
        <property type="entry name" value="GP_PDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03009">
        <property type="entry name" value="GDPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10110">
        <property type="entry name" value="GPDPase_memb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="SSF51695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51704">
        <property type="entry name" value="GP_PDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="123"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="166"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="217"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="260"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="323"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="domain" description="GP-PDE" evidence="2">
        <location>
            <begin position="351"/>
            <end position="581"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="611" mass="66228" checksum="982001689CBB2A63" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INV6</accession>
    <name>A0A518INV6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Adenosine 5'-phosphosulfate reductase</fullName>
            <shortName evidence="3">APS reductase</shortName>
            <ecNumber evidence="3">1.8.4.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">5'-adenylylsulfate reductase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Thioredoxin-dependent 5'-adenylylsulfate reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 6" type="primary">cysH</name>
        <name evidence="6" type="ORF">Mal33_07410</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>[thioredoxin]-disulfide + AMP + 2 H(+) + sulfite = [thioredoxin]-dithiol + adenosine 5'-phosphosulfate</text>
            <dbReference type="Rhea" id="RHEA:21976"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17359"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:58243"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="1.8.4.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="3">Binds 1 [4Fe-4S] cluster per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the PAPS reductase family. CysH subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.8.4.10" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00049">
        <property type="reaction ID" value="UER00059"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043866">
        <property type="term" value="F:adenylyl-sulfate reductase (thioredoxin) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004604">
        <property type="term" value="F:phosphoadenylyl-sulfate reductase (thioredoxin) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019379">
        <property type="term" value="P:sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01713">
        <property type="entry name" value="PAPS_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00063">
        <property type="entry name" value="CysH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004511">
        <property type="entry name" value="PAPS/APS_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002500">
        <property type="entry name" value="PAPS_reduct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01507">
        <property type="entry name" value="PAPS_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000857">
        <property type="entry name" value="PAPS_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00434">
        <property type="entry name" value="cysH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAPS_reduct" evidence="5">
        <location>
            <begin position="79"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile; cysteine thiosulfonate intermediate" evidence="3">
        <location>
            <position position="268"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="160"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="242"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="245"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV54776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="274" mass="30681" checksum="48AC9D1AFD996D5A" modified="2019-10-16" version="1">MSEHKLAEPSERPTLKVLRPDESPASAPAEPQGALAADPPLIPGDDLFGELAAHSQRLETATPQEILAWAVEHYAPRFTMATAFGPEGMCLIHMFSEIAPQTPIFNLETGYQFKETLALREQVRERYGITIEYKYPDQTVEEYEAANGGPVYKTDTNRCCFDRKIKVLHQAARGMHAWSSAIRRDQSPDRAEHPIVGWDKKFQLVKISPLANWTKKDVWGFISKNDIPYNPLHDQGYPSVGCWPCTRSIALGEDERAGRWSGSAKTECGLHSSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP09</accession>
    <name>A0A518IP09_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">N-substituted formamide deformylase</fullName>
            <ecNumber evidence="4">3.5.1.91</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">nfdA</name>
        <name evidence="4" type="ORF">Mal33_07940</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.5.1.91" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01300">
        <property type="entry name" value="YtcJ_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013108">
        <property type="entry name" value="Amidohydro_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033932">
        <property type="entry name" value="YtcJ-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07969">
        <property type="entry name" value="Amidohydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021982288" evidence="2">
        <location>
            <begin position="20"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="domain" description="Amidohydro_3" evidence="3">
        <location>
            <begin position="69"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="145"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV54829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="574" mass="63880" checksum="05781A6DC4B4294E" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP68</accession>
    <name>A0A518IP68_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Inner membrane protein YihN</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">yihN</name>
        <name evidence="2" type="ORF">Mal33_08270</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="148"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="188"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="229"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="300"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="326"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="357"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="397"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="426" mass="45436" checksum="58DADC81EA75E503" modified="2019-10-16" version="1">MTKPDQPPSPIARAIAMFTLIVAGEAVFFLPFVLPRVFRPTLLEVFQLTNLELGIAFSLYGVVAMIAYFPGGPLADLFSARKLMAVALLATAAGGLLLASIPSLGGLKLLYGFWGATTILLFWAPLIRATRAWGGAMLPGRAFGFLDGGRGLVAAAIGSGAVALFALLMPDEVQTASAAQRTHAFQQVVYLFTGITLAAAALVWFALPRQGEPSAPIELKRPLGAVRRVLKMPTVWLQAIVVVSAYIGYKGLDNISLYAHEVLEFDEVQAAQVGTLSMWMRPVAAVAAGLLADRFGVARLTILSLLGFGIGSGMLAVGAFPPGMSMFFFATMISTSACVFALRGLYFAMMEEGRVPFGDTGCAVGIVSVIGFTPDVFMGPWMGILLDRWPGELGHQYFFASLAVAATIGLIASIAFWRIVRRWNEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPG2</accession>
    <name>A0A518IPG2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA-binding protein HU 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">hupA</name>
        <name evidence="2" type="ORF">Mal33_09300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial histone-like protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000119">
        <property type="entry name" value="Hist_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010992">
        <property type="entry name" value="IHF-like_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33175">
        <property type="entry name" value="PTHR33175"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00216">
        <property type="entry name" value="Bac_DNA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00411">
        <property type="entry name" value="BHL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47729">
        <property type="entry name" value="SSF47729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="100" mass="10755" checksum="248C4F72D01E7A25" modified="2019-10-16" version="1">MVGKAPTKTEIFNAIAESTQLTKKDIAAVFDALSAEVATAVQGPGQFTIPGLCKVTVRETPAKPKRKGRNPATGEEIWLQPKPASKKVTIRPLKALKEMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPN6</accession>
    <name>A0A518IPN6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_10110</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="53"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="143"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="503"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="637"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="752"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="816"/>
            <end position="836"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="922"/>
            <end position="1125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="637"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="660"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="973"/>
            <end position="992"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="994"/>
            <end position="1018"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1035"/>
            <end position="1095"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1228" mass="135896" checksum="DE134E4D75EF7F85" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPW1</accession>
    <name>A0A518IPW1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Purine nucleoside phosphorylase</fullName>
            <ecNumber evidence="3">2.4.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Inosine-guanosine phosphorylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">punA_1</name>
        <name evidence="6" type="ORF">Mal33_11050</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 3">Purine metabolism; purine nucleoside salvage.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the PNP/MTAP phosphorylase family.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.1" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00606"/>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004731">
        <property type="term" value="F:purine-nucleoside phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009116">
        <property type="term" value="P:nucleoside metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09009">
        <property type="entry name" value="PNP-EcPNPII_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000845">
        <property type="entry name" value="Nucleoside_phosphorylase_d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035994">
        <property type="entry name" value="Nucleoside_phosphorylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011268">
        <property type="entry name" value="Purine_phosphorylase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11904">
        <property type="entry name" value="PTHR11904"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01048">
        <property type="entry name" value="PNP_UDP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000477">
        <property type="entry name" value="PurNPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53167">
        <property type="entry name" value="SSF53167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01697">
        <property type="entry name" value="PNPH-PUNA-XAPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PNP_UDP_1" evidence="5">
        <location>
            <begin position="30"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphate binding" evidence="4">
        <location>
            <begin position="88"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="37"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="68"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="205"/>
        </location>
        <ligand>
            <name>a purine D-ribonucleoside</name>
            <dbReference type="ChEBI" id="CHEBI:142355"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="224"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="247"/>
        </location>
        <ligand>
            <name>a purine D-ribonucleoside</name>
            <dbReference type="ChEBI" id="CHEBI:142355"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR000477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000477-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV55136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="287" mass="31495" checksum="918BBA2F71E9B16F" modified="2019-10-16" version="1">MTKHPNQQCPAERVLRTAEFIACKLAELPRVAIILGSGLGNLADYIEDAIAIDYSDIPNWGQSWIAGHSGQLIFGWLDSQPVIAMSGRFHRYEGWTTEQVSFPVRVLAAIGSHTLIVSNAAGGLNPKYRVGDIVVIRDHIDMLHGRPGQRFDYGIYPPQTRSDAPLRGASPYDQTLSEKALETARLNGFPAHSGTYLATLGPSYETRAEYRFMRKIGADVVGMSTVPEVLQAQRIGMRVLGMSMVSNIARPDAPQRTDHADVLAAAQIAEPRMRAIVREAVQRSTTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQ07</accession>
    <name>A0A518IQ07_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Thiamine-monophosphate kinase</fullName>
            <shortName evidence="2">TMP kinase</shortName>
            <shortName evidence="2">Thiamine-phosphate kinase</shortName>
            <ecNumber evidence="2">2.7.4.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2 5" type="primary">thiL</name>
        <name evidence="5" type="ORF">Mal33_11490</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + thiamine phosphate = ADP + thiamine diphosphate</text>
            <dbReference type="Rhea" id="RHEA:15913"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:37575"/>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; thiamine diphosphate biosynthesis; thiamine diphosphate from thiamine phosphate: step 1/1.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="2">Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the thiamine-monophosphate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.16" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00060">
        <property type="reaction ID" value="UER00142"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009030">
        <property type="term" value="F:thiamine-phosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009229">
        <property type="term" value="P:thiamine diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02194">
        <property type="entry name" value="ThiL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.650.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02128">
        <property type="entry name" value="TMP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010918">
        <property type="entry name" value="PurM-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036676">
        <property type="entry name" value="PurM-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016188">
        <property type="entry name" value="PurM-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036921">
        <property type="entry name" value="PurM-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006283">
        <property type="entry name" value="ThiL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30270">
        <property type="entry name" value="PTHR30270"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00586">
        <property type="entry name" value="AIRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02769">
        <property type="entry name" value="AIRS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005303">
        <property type="entry name" value="Thiam_monoph_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55326">
        <property type="entry name" value="SSF55326"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56042">
        <property type="entry name" value="SSF56042"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 5" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0784">Thiamine biosynthesis</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AIRS" evidence="3">
        <location>
            <begin position="25"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="AIRS_C" evidence="4">
        <location>
            <begin position="171"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="26"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>4</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="43"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="72"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="119"/>
            <end position="120"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="146"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="193"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>5</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="246"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="299"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV55179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="303" mass="31711" checksum="CACFB933921BABC4" modified="2019-10-16" version="1">MEQSFLAWLRGRQRLLPQVAVGIGDDAAVIDWPQSRQLVTSVDTIVDGVDFLLDQHSPAAIGHKALAVNLSDLAAMAADPVAALVAISLPNENATQVAAAVYEGILATAADFGVAISGGDITCYDGPLAISITIIGQAEPQKSWLRSGAQPDDAVLVSGSLGGSILQKHLAFTPRVRLAQQLRDNFTINAAIDISDGLLLDLDRLCAASGCGIELELDRVPVSEDAQALSQQDGGDPLEHALGDGEDYELILTCPADQAAEILAADLGTPLTQIGTLTSRTGLWSKLPNKLIRLSPRGFVHGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQ53</accession>
    <name>A0A518IQ53_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">O-Antigen ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_11720</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007016">
        <property type="entry name" value="O-antigen_ligase-related"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04932">
        <property type="entry name" value="Wzy_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="2 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="6"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="28"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="52"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="83"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="111"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="140"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="188"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="221"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="259"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="355"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="418"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV55202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="466" mass="51593" checksum="0671FE07B62BE53D" modified="2019-10-16" version="1">MEFLGLLFALAAGVWGIYLAHRVSLQMLVLAVLIIGTVFGPNFFAINGPIQFSIDRILWFAMLGLFVVRCLRDGTRPIEMNRMDWLIVAFVGWLLLSLITTDAPRSGTEPLARWIFYAFLPLGTYFVARFSRLSRRELRIVQRTFIGLGIYLGLTALAEKAELKAVIFPRFIIDPEFVEFLGRGRGPLLNPTGNGFLLSIAFAAMLLAFQQRNRIAKFGYGFAMLAAAGGVYATLTRSVWIAAAAAVSLSQMNRISRGLRIWAVASAIVLAAVIAIGFGDKILHLKRDKNLSASAAAESIELRPMLAIIAWEIFKDHPLCGVGYGHYFDFNQEYAQAPQWEMPLRKATPYHQHNVLLSYLVDSGLIGAGLFTILVICWGFTGWQIARSSSACPEAQNIGLLMLATVSSYLLNGMFQDVSIIPMLNMYLFYVAGLTVSVDTVDGRLPQRNLAQQRPAAILRQPATSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQ71</accession>
    <name>A0A518IQ71_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transcription antitermination protein NusB</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Antitermination factor NusB</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">nusB</name>
        <name evidence="8" type="ORF">Mal33_11730</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the NusB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006353">
        <property type="term" value="P:DNA-templated transcription, termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031564">
        <property type="term" value="P:transcription antitermination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.940.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00073">
        <property type="entry name" value="NusB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035926">
        <property type="entry name" value="NusB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011605">
        <property type="entry name" value="NusB_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006027">
        <property type="entry name" value="NusB_RsmB_TIM44"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11078">
        <property type="entry name" value="PTHR11078"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01029">
        <property type="entry name" value="NusB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48013">
        <property type="entry name" value="SSF48013"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01951">
        <property type="entry name" value="nusB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 6" id="KW-0889">Transcription antitermination</keyword>
    <keyword evidence="4 6" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="NusB" evidence="7">
        <location>
            <begin position="5"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV55203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="138" mass="15857" checksum="65C4E7DD2FA6F1BE" modified="2019-10-16" version="1">MATRRRAREVTLQLLYEYDFGTERSRSDRDQFIETRMRNHPALSDFARSLLGGVMNNRGQIDSLLARHSSNWSISRMAVIDRNILRLGIYEIVFGKTPGRVAINEAIEIAKRYGDRKSRGFVNGILDRILSESKQAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQB7</accession>
    <name>A0A518IQB7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_12590</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039968">
        <property type="entry name" value="YghO-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41368">
        <property type="entry name" value="PTHR41368"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="202"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="379" mass="43750" checksum="87D9D29B8B958AAE" modified="2019-10-16" version="1">MTETLKIWPVQSSKDQKQFLSLPWQIYRGDENWIPPIRSHQREMVNFKPHPFYQDAEIQTFLAARGNKVVGRIAALVNHAHNRQFDEQRGFFGFFECEDDQEAATGLFEAAAKWLADKGMDAMRGPVNPSLNYECGLLIDGFDRPPTFMMTYNRPYYPALVESFGLAKVEDLYAYDVELSMLDNLDPKLKFVVEEVARRFEVETRPLSRKNFMSDVRLFLDIYNKSLVNTWGYVPLSEAEIDHQSKQLRMLVTPEMTSIASIKGKPIGACFGLLDYNPLIKKIDGKLFPFGWLRLLLGRRHLKRARLLSTNVLPEYQRWGLGVVTIYRILPDALKFGLTEGELSWVLESNQLSRASIERGGAQITKTYRLYDRDLADFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQK6</accession>
    <name>A0A518IQK6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cobalt-zinc-cadmium resistance protein CzcA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">czcA_3</name>
        <name evidence="3" type="ORF">Mal33_13520</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2090.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82714">
        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="391"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="472"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="502"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="562"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="893"/>
            <end position="913"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="920"/>
            <end position="940"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="946"/>
            <end position="973"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="994"/>
            <end position="1016"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1022"/>
            <end position="1052"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="273"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="280"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1079" mass="118653" checksum="07AABDAC697D26E5" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQW3</accession>
    <name>A0A518IQW3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_14610</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="314" mass="36072" checksum="4EBE930FC79C1CA7" modified="2019-10-16" version="1">MSDFYCQRFRDHHSTIRSIADKNLELGVFDFFDKQQLARFSVVARDIIKAFREGWFKDPGLCEAIGEWLWMNYMVGERDHSSHFSLLNSELRKWWYGLAKTSQFHHEVEGRRVTIKGGIERSFEETRDLADLVYAIAGGGTCEELAIKEHLQKLKAAISRASTDAPETITDLFVAACAYSCVDRRYDTVISRIIEAWDPYDIDWDAMEVLVAELKEGHVKGSSKPGQSLEDLEADTPPLDTASVDWIEATQKNIEILKIKISSLRRYRTSSLKGRSLGPYFGVDKYGRRWRKDPNRTEGSNVFYWRPSLPPSVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IR13</accession>
    <name>A0A518IR13_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_15140</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="149" mass="15403" checksum="AE0711994B80E8A8" modified="2019-10-16" version="1">MQKLQLSLFVLSYLLCVGCGGDGVNRVAINGQLQSDDGPIANASVQFIPEAGTTGDGALGMSDSEGKFSVISSRDGDGGLPPGNYRVRISQMVDGNGTVLPADATQAEYPDSREGIPAPYSTLESPLQVTISEDGGDVVIALPSESKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IR19</accession>
    <name>A0A518IR19_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Rdx family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_15110</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011893">
        <property type="entry name" value="Selenoprotein_Rdx-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10262">
        <property type="entry name" value="Rdx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02174">
        <property type="entry name" value="CXXU_selWTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="103" mass="11888" checksum="1A7F6BF0FD2A61C4" modified="2019-10-16" version="1">MKNRIVIRYCTGCRWLLRAAWMAQELLTTFEAELDEVALAPTDGGRFVIELNGDMIWDRHRDHGFPEIKVLKQLVRDRVAQGRDLGHLDRANPDPLPKSPDNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRK1</accession>
    <name>A0A518IRK1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Epoxyqueuosine reductase</fullName>
            <ecNumber evidence="8">1.1.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">queG</name>
        <name evidence="8" type="ORF">Mal33_16900</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.-.-" evidence="8"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008616">
        <property type="term" value="P:queuosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004155">
        <property type="entry name" value="PBS_lyase_HEAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004453">
        <property type="entry name" value="QueG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013542">
        <property type="entry name" value="QueG_DUF1730"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30002">
        <property type="entry name" value="PTHR30002"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08331">
        <property type="entry name" value="DUF1730"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00567">
        <property type="entry name" value="EZ_HEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00276">
        <property type="entry name" value="TIGR00276"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-0671">Queuosine biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="7">
        <location>
            <begin position="183"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV55711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="383" mass="42417" checksum="6641936C0EF22AAD" modified="2019-10-16" version="1">MSSNSEAPADFTQLLKSQANQLGFHLSGACPAVEPSGYHRLLDWIDSGKAGEMDYLDARRDAYRDPQHVMPGVQSLLVLGLPYRTAQPEEVGPMQGRFARYAWGSIDYHDLVHRKLKQLKRWVLQERPGATVRGVVDTAPLLEREFAQLAGIGWTGKNTLLINKWQGSYFFLAALLVDFTLTYDAPHESDHCGKCRACLDACPTAAFPEPGVLDATRCISYLTIEHRSAIPQELRQPIGNWVFGCDVCQDVCPWNRRGSEAQEAEFQPLATQNPAELISLFSLTDDEFRSRYRKTPLWRTRRRGLLRNAAIVLGNAGDPAAIDALNQGLQDSEPLVRGASAWALGRIGTSAAVDRLREGCDRETDAMVQQEIAEALRGAQPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRL7</accession>
    <name>A0A518IRL7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator MprA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">mprA_1</name>
        <name evidence="3" type="ORF">Mal33_17110</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13581">
        <property type="entry name" value="HATPase_c_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="3"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="301" mass="33610" checksum="834CA65C6AC172E8" modified="2019-10-16" version="1">MANVLLAEDSSTQVVLLRSLLEEDSHQVRVAADGQVALEMVAHQVPDVVVTDMQMPNMNGLELVKSLRQIYPQVPVILITAQDSEELAVQALKEGAAAYLPKSRLDEELLDSVTHVLSLLDTEMSYKNLIDCLDYYEFQFTLENDPKLIAPLVNLIQQMAAGIQYCDDVTRARIGMALEQALRNALYHGNLELSRDALRKDEELRVVGEPSIVDRRRHEPPYADRKIHFRAKLGHDQLQFTVRDDGAGFDCAAVEPPEQKHLDDQTGRGLLLIQSFMDEVAFNPEGNEITLTSHVAEVAGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRL9</accession>
    <name>A0A518IRL9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_17250</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007495">
        <property type="entry name" value="NqrM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04400">
        <property type="entry name" value="NqrM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="131" mass="13469" checksum="3BCAB85B0808706A" modified="2019-10-16" version="1">MKAVPPLATVKSNFSQPSYAHFIMIGMDILANSIGIVAQSAEVASETGSGSHVAVIVGITLAAFLLVCLGMAVGVMFGRRPISGSCGGLGNVTNESGEKSCALCQNPSEACKELRNRMTPAEEASEHEAAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRR3</accession>
    <name>A0A518IRR3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF1570 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_17580</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011464">
        <property type="entry name" value="DUF1570"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07607">
        <property type="entry name" value="DUF1570"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021867449" description="DUF1570 domain-containing protein" evidence="1">
        <location>
            <begin position="28"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1570" evidence="2">
        <location>
            <begin position="202"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="361" mass="40331" checksum="ECA268AF84764FBC" modified="2019-10-16" version="1" precursor="true">MSAPHRIVSILAALALIAATAESKLHAADRDPMVAMSLGGEFVQGMSLLWTPDRAVVLQRDGRLFDFDPADASQLTIDAGSFDAASSAELRSQLYREFGSTHQVTSTSNYLVVHPTRGTHWPQLLEDLHRSFLQHCRTRNLPLRKARFPMVAIVFPDRSSFLRYAQSDRGRPLGANVLGYYSQNSNRVALYDHGASAGGVSSTIRHEAAHQSAFNWGIHSRVAKQPHWIIEGFGTMFEAAGIHDPANHPSLQDRVNREMLASLRRRFPDSQSLAAAIEELVQDDQRFASDAESAYAVAWAMTFYLADRRPDVLRQLVTHYSSRLPFITYPAVERRSDFERAIGISIPMLASQIQQFLSDVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRR5</accession>
    <name>A0A518IRR5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glucosamine-6-phosphate deaminase 1</fullName>
            <ecNumber evidence="2">3.5.99.6</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">nagB_1</name>
        <name evidence="2" type="ORF">Mal33_17640</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.5.99.6" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004342">
        <property type="term" value="F:glucosamine-6-phosphate deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006044">
        <property type="term" value="P:N-acetylglucosamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01399">
        <property type="entry name" value="GlcN6P_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006148">
        <property type="entry name" value="Glc/Gal-6P_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004547">
        <property type="entry name" value="Glucosamine6P_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11280">
        <property type="entry name" value="PTHR11280"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01182">
        <property type="entry name" value="Glucosamine_iso"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucosamine_iso" evidence="1">
        <location>
            <begin position="9"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="255" mass="27715" checksum="29A901B65AD36D06" modified="2019-10-16" version="1">MDLVIAANSDLMGREAAQIAAADLVAAIKNSGQARLLVATGASQFTVLEHLIQHDEIDWSVVDGFHLDEYEGISPDHPASFCKYLKERFVDRVGLRSFRFLRGDQDIEATVSEAAAAVSAAPIDVAMVGIGENAHLAFNDPPADFETNDPYLIVDLDEACRLQQVGEGWFDSLESVPKRAISMSVNQILKSKRIVCSVPDERKAKAVQGSFEGEICPKTPASILQRHPQTTLLVDEPAASLLSAESKEKARKVQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRV8</accession>
    <name>A0A518IRV8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Outer membrane efflux protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_18040</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="113"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="469"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="714"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="113"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="714"/>
            <end position="734"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="759" mass="83957" checksum="DC37680349765883" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRY4</accession>
    <name>A0A518IRY4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Na(+)/H(+) antiporter subunit F</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">mrpF_1</name>
        <name evidence="9" type="ORF">Mal33_18370</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015075">
        <property type="term" value="F:ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007208">
        <property type="entry name" value="MrpF/PhaF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34702">
        <property type="entry name" value="PTHR34702"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04066">
        <property type="entry name" value="MrpF_PhaF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="29"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="62"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV55858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="93" mass="10147" checksum="35EC87329006EEAB" modified="2019-10-16" version="1">MTGIFLVTSIAILITMALALIRAMLGPTVFDRVLALNMVGTKTVLLISVVDVATERGDFLDLALLYSLMNFIGMVALLRFTEYGSFSREGTEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IS55</accession>
    <name>A0A518IS55_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_19080</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021215">
        <property type="entry name" value="DUF2752"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10825">
        <property type="entry name" value="DUF2752"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022140757" evidence="2">
        <location>
            <begin position="19"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="120" mass="12716" checksum="91942CEB70CF23B9" modified="2019-10-16" version="1" precursor="true">MCLFAMLATAAWLRPASAGLGTHHQLGLPPCSFRVLLGMRCPACGMTTSWSHYVRGQWVSSLHANPGGFMLAVLATVVGVGAVRVGYTGRPADPQQTWLIAIGLIGAMSVALVDWIVRLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISP2</accession>
    <name>A0A518ISP2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Probable endonuclease 4</fullName>
            <ecNumber evidence="7">3.1.21.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Endodeoxyribonuclease IV</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Endonuclease IV</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">nfo</name>
        <name evidence="9" type="ORF">Mal33_20840</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>Endonucleolytic cleavage to 5'-phosphooligonucleotide end-products.</text>
            <dbReference type="EC" id="3.1.21.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 3 Zn(2+) ions.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the AP endonuclease 2 family.</text>
    </comment>
    <dbReference type="EC" id="3.1.21.2" evidence="7"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008833">
        <property type="term" value="F:deoxyribonuclease IV (phage-T4-induced) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00019">
        <property type="entry name" value="AP2Ec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00152">
        <property type="entry name" value="Nfo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001719">
        <property type="entry name" value="AP_endonuc_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018246">
        <property type="entry name" value="AP_endonuc_F2_Zn_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013022">
        <property type="entry name" value="Xyl_isomerase-like_TIM-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21445">
        <property type="entry name" value="PTHR21445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01261">
        <property type="entry name" value="AP_endonuc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00518">
        <property type="entry name" value="AP2Ec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="SSF51658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00587">
        <property type="entry name" value="nfo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00729">
        <property type="entry name" value="AP_NUCLEASE_F2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00730">
        <property type="entry name" value="AP_NUCLEASE_F2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00731">
        <property type="entry name" value="AP_NUCLEASE_F2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51432">
        <property type="entry name" value="AP_NUCLEASE_F2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6 7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7 9" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="4 7 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0540">Nuclease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="AP_endonuc_2" evidence="8">
        <location>
            <begin position="24"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="149"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="186"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="220"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="233"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="235"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="265"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV56105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="292" mass="31549" checksum="7DF7CEC03D6136A2" modified="2019-10-16" version="1">MPKASSLRLGAHMSIAGGLEKAVQRAHDATCDVVQIFTKNNNQWAAKPLTEATIEAWRAALAEYSIGAPIAHASYLINMASPNDELFRKSIEALVVEWQRAEQLQLEGLVVHPGAFTDSSEAEGLEKIVIAVREIIERVQPQHCRLLLENTAGQGSCLGHAISHLGTMFRGIDNTENLGVCFDTCHAFAAGYDLTTDAGYAAMSAEIDSELPAGAIRAVHINDSKKGCGSRVDRHDHIGQGMITLDGFRRVLADPVFNVCPMYLETPKGTDPETGEDLDTNNLNTLRSLAGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IT16</accession>
    <name>A0A518IT16_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DNA primase TraC</fullName>
            <ecNumber evidence="3">2.7.7.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">traC</name>
        <name evidence="3" type="ORF">Mal33_22260</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.7.-" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017113">
        <property type="entry name" value="Antirestriction_ArdC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013610">
        <property type="entry name" value="ArdC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041459">
        <property type="entry name" value="MPTase-PolyVal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08401">
        <property type="entry name" value="ArdcN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18818">
        <property type="entry name" value="MPTase-PolyVal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037112">
        <property type="entry name" value="Antirestriction_ArdC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ArdcN" evidence="1">
        <location>
            <begin position="6"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="MPTase-PolyVal" evidence="2">
        <location>
            <begin position="154"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="303" mass="34538" checksum="5050571B969C2838" modified="2019-10-16" version="1">MATTTEIRQQITNDIIAALSSDQLPPWRKPWSNDPNAPGLHTSLSTGNCYRGINQMILQLSAWKRKFTSKWWGTFKQIQANGGCVNRGQKATKIILWKPIDRKRTSEQGESIDDKFFVMREFAVFNASQTSGMEQFQIGYSQSESINERHYGDADEVIEAVGADIRYGGNQAFYSPSGDYIQMPFRRQFVKPEAYYETCFHELCHYSESRTGLDRAKPENSYDFLELVAEIGACFLMGELQMPTMENLENHAAYLKSWLKGMNDDPKFIFRAAAQSSKATDYILSFSRKDETIAETIEEPVCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IT37</accession>
    <name>A0A518IT37_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Alpha/beta hydrolase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_22310</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="161" mass="17691" checksum="F26056E73C9C2C55" modified="2019-10-16" version="1">MKILFLHGWHSIVGGVKPTYLKDAGHEVINPALDDDDFEAAVSTAQTEYDQHHPDVIVGSSRGGAVAMNIESKDTPLVLLCPAWKNWGTATTVKANTIILHSRKDDVIPFADSEELVTNSGLPPETLIEVGDDHRLADPEPLKAMLETCERLEKGARDERR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IT57</accession>
    <name>A0A518IT57_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_22580</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="SSF56219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="166" mass="18327" checksum="87ED1C4F587F8ECE" modified="2019-10-16" version="1">MPISRRQFCGAVGASIAAANSNLFADDSKPKPKPKPKPLRVIAYNIYKCTGWPDQRQLAQQAVAKGQMAKRLAMELALHDPDIINFSESPSEKLTKEVAELLGMNHVRFPSGGNWPGTLLSKFEITESQNAPMKGERPKELFTRHWGRATVKLTSGDPLIVHSAHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IT89</accession>
    <name>A0A518IT89_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_22960</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022145063" evidence="1">
        <location>
            <begin position="25"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="223" mass="23820" checksum="4B598815768C24F5" modified="2019-10-16" version="1" precursor="true">MFARVSRFVLFIAAILVAAPAAMAQLLHTATPQQSIGDSYSEQLGIRWGLRGPGWFVNVPNGVGNPAFGGADPNAGLTGGFAGRRGNVSGSLGFQWYQGSNRSMSTVAPSLTTLDGYPGSMFSGSVRPFVTSVTPAVGSFTPPNEGIRQAGLQRQQATLDSIASRKVEIHNEKADQYWSRALRAEQQGNLKMARANYRLALPHASGSLRAEIVQRMAARGWTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITW3</accession>
    <name>A0A518ITW3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_24910</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="74" mass="8085" checksum="F7E2E0E43CAF6DE0" modified="2019-10-16" version="1">MSLEFIAALVFTNIGGAIAAWVALNSRVSANEQLTDTIRSKIEKHDHAIYGNGRKGLNERVTVLESTSQRKTNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IU35</accession>
    <name>A0A518IU35_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GalNAc(5)-diNAcBac-PP-undecaprenol beta-1,3-glucosyltransferase</fullName>
            <ecNumber evidence="2">2.4.1.293</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">pglI</name>
        <name evidence="2" type="ORF">Mal33_25970</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.4.1.293" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="4"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="297" mass="33614" checksum="8740749CAC01278F" modified="2019-10-16" version="1">MKISVAICTWNRSGLLRRTLQSIAEMEMGDPIEWELIVVDNNSSDDTADVIGSFALQLPIRYVHEPQQGLSLSRNRAIDTATGDYILWTDDDVLVSKQWLNAYRSAFEAAPDIAFFGGCIEPWFEPPGCPDWISETWEKCNPAFSPRMLGDAEVELTAERLPYGANFAVRTDVQQAHRYDPRWGRVGSGMMGGEEIAVLREIVRCGGRGRWVPGAPLRHIVPARRASEKFIRDYFVGQGMENVAAGRTVTGRMANGFDAMYSMLLYRIKRRFVEPDEWVSHMIRASISWGEFRAQRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUH5</accession>
    <name>A0A518IUH5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Citrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_27390</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015128">
        <property type="term" value="F:gluconate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003474">
        <property type="entry name" value="Glcn_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30354">
        <property type="entry name" value="PTHR30354"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02447">
        <property type="entry name" value="GntP_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="178"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="232"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="282"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="441"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="465" mass="49079" checksum="85077CF21FA0AEDF" modified="2019-10-16" version="1">MNLLIILAALGFLMLAAYRGYSVILFAPLAAMGAVLLTSPAEVAPMFTGLFMDKMAGFFKLYFPIFLLGAVFGKTMELSGFAKSIASAIIELLGRQRSVLSIVIVSALLTYGGVSLFVAVFAVYPFAAELFRQSGIPKRLIPATIALGAFSFTMDSFPGTPQIQNVIPAAFFKTDIYAAPWLGILGGLFTLFAGLLFLEWRVRVAAANEEGYGDVLLNEPAAFEHDRLPSPWLAMLPLLVVAVANKILTGAIPRLYGESHAFIPAVVGTSEPVVQDVAKISAIWSIEAALILGILTVMLLAWRHLFKKLSEGTKPAIAGALLAATNTASEYGFGAVIAALPGFLIVSDALRWIPNPLVNEAVTVTTLAGITGSASGGLSIALAAMSETFIANAEAAGIPLEVFHRVASMASGGMDTLPHNGAVITLLAVSGLTHRQAYGNIFGITLIKTLAVFVVIAIYQWTGLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUL9</accession>
    <name>A0A518IUL9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_27880</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021844206" evidence="1">
        <location>
            <begin position="25"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="146" mass="15720" checksum="829C74BDA8F226E7" modified="2019-10-16" version="1" precursor="true">MTCCTNRSCGTFCLLSCVLTIAIAGCGPSAPSRQEISGSITWDGEPLSSTSIVFRSQGSGGQGVATEVTDGQFQVSSEQGPTPGLYDVVLLPVQPELEDYEALRKQGKMPLTGPKIPHRYQHRGELTAEVKADQPNRFVFEISSKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUP0</accession>
    <name>A0A518IUP0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_27980</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011453">
        <property type="entry name" value="DUF1559"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07596">
        <property type="entry name" value="SBP_bac_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="329" mass="35031" checksum="BB5735CC0061BA8A" modified="2019-10-16" version="1">MRQRFAGFTLVELLVVIAIIGILVSLLLPAVQQAREAARRMQCTNRLKQLELAVHNYHDTFGVFPSGSINGAGDNPNGAHGSGAKAIGGSWNLLILAQMEQPALHDQFMTIANERPEVADWLGNGVYTSQGITVGSEQLPALLCPSHPSNVEKLANGTGLEHLARGNYAACYGKAGYGAIHTEDANEGGVFGNNSRFQMRDVRDGTANTISISELKFRLRSSSGPSYQDSRGTWAYAVMGGDIFSTKTGPNSATPDGVWGCRNHPQSGMPCVQIGSPYTELYAAARSYHPGGVMGAMADGSVRFFTETVDLAVWQAIGTRSGGEVAELP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUW8</accession>
    <name>A0A518IUW8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SGNH_hydro domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_28710</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022243286" description="SGNH_hydro domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="SGNH_hydro" evidence="2">
        <location>
            <begin position="57"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="294" mass="32594" checksum="0ECD9DC664906B05" modified="2019-10-16" version="1" precursor="true">MRLKLTCLFLALTICCGFADNSTADENASLQPEDRIALIGGTWVERMQQNGYFETALQSLAPQKKLVVRNLGWSGDNARAEARAVFGSPQEGYARLQRDLAAANPTIVVVGYGFAEAINGMEAAERFPADLARLLDDQAAAGVRVVLLQPFHMPGVLTPDYDAADQSVRQTIAQAARERKLPLIDLAPWVSDADFDNGLHLTEQGYQQLGDRLARELLHQAAAPAIDYTTAKTKALRDKVIEKNQLFFHRYRPQNETYLFLFRKHEQGNNAVDIPRFDPLIEALDGEIQQAAGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IV00</accession>
    <name>A0A518IV00_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Bifunctional protein GlmU</fullName>
            <ecNumber evidence="1">2.3.1.157</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">glmU_1</name>
        <name evidence="1" type="ORF">Mal33_29180</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.3.1.157" evidence="1"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019134">
        <property type="term" value="F:glucosamine-1-phosphate N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023917">
        <property type="entry name" value="Bifunctiontional_GlmU_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13562">
        <property type="entry name" value="NTP_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03991">
        <property type="entry name" value="alt_bact_glmU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="415" mass="45744" checksum="A7A1C32EEAFAF221" modified="2019-10-16" version="1">MRILLFEDSSTDQLAPITVSRPAYAITCASYRLIDWVRRMNASIAGEVRAYLQPIQQADFADLQSPADWQQGSEPVLAINARCVPSIENFQAFQRIAARQNSGIVKSGHDVAAILLMPQDLIRSKSMPGTSVSQQMLAVDGIAPIDESVAMFDWPHEVVRWHMQLMNASLEDRIAQGNYEQREDGVFLAPGAKIGEYAVIDTSEGPILLDENVTVGPFCYLSGPVYAGPGTRVIEHAALKDGVSLGHTVKIGGEVEASVIEPYTNKQHHGFLGHSYLGSWINLGAGTCNSDLKNTYGRINIEYDDRKMATEMQFLGCIVGDYSKSAINTGIFTGKVIGVCSMLYGFVTQNVPSFMNYAQIFGQVAEIPADVMVATQARMFARRKVQQRQCDIDLIRAMYDQTSSQREQGEHAEIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IV83</accession>
    <name>A0A518IV83_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NADH dehydrogenase-like protein YjlD</fullName>
            <ecNumber evidence="3">1.6.99.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">yjlD</name>
        <name evidence="3" type="ORF">Mal33_29970</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.6.99.-" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="378"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="domain" description="Pyr_redox_2" evidence="2">
        <location>
            <begin position="6"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="445" mass="48786" checksum="DB06E7210384B16D" modified="2019-10-16" version="1">MNTQPHVVIVGGGFGGLQAAKQLRKSNVRVTLVDRHNYHLFQPLLYQVATGGLSPANIATPLRAILRKQANCQVLLAEVTDFDVANNRLVLADGELTYDTLVLAAGATHSYFGNDQWAEFAPGLKTLGDATEIRRRIYLAFEAAEREPDPEARKALMTFVVVGGGPTGVELAGTLSEIAEHTLARDFRNIRPQDARIMIIEGAPHVLNHYDEALSQRAADKIRQFHIEVHTHTRVNEITADHVRMSSEGCETIVPTRTVLWGAGVQANPLGKRLAAACGLETDRAGHIPVDEFLNVVGHKNIFAVGDIATCLDEEGKPLPGLAAVAMQQGGYVADTIAARVAGTGQSEPFKYHNKGTMATIGRAAAVVQIGKRQFCGFFAWLLWLFVHLLLIVQFQNRVLILFQWAWNYATFNRSARLITGDDHVVIVRRTKNSDPHAEKTVEVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IV84</accession>
    <name>A0A518IV84_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_30020</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="99" mass="11033" checksum="D4712A1FC6E9D7DB" modified="2019-10-16" version="1">MATIGRAAAVVQIGKRQFCGFFAWLLWLFVHLLLIVQFQNRVLILFQWAWNYATFNRSARLITGDDHVVIVRQPNGTEATEEDSPAQPAGNLSADSGEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVA0</accession>
    <name>A0A518IVA0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter ATP-binding protein YtrE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ytrE_1</name>
        <name evidence="5" type="ORF">Mal33_30090</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="2"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV57008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="227" mass="25032" checksum="0BE19E6E6066ADEA" modified="2019-10-16" version="1">MYRLQSVTHTYQRRGQIVTALDDSNLEIADNDFIAIVGPSGSGKTTLLSVLGGMLAPTTGQIMLDGLSLYDLSIESRAELRREKIGFVFQSFNLIHWLSACENVQIPLMLSGLSAQRQREHALELLDRVGLADRSDHRPSEMSQGQQQRVALARTLANDPRIILADEPTGNLDAETRVQVMEYLTEFHNDGRTIVMVTHDAQTASFANRTIRLVAGVTQEVATAKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVG6</accession>
    <name>A0A518IVG6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">VWFA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_30820</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="3">
        <location>
            <begin position="163"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV57081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="332" mass="35553" checksum="75318EB07177AC1E" modified="2019-10-16" version="1">MTLAYRPDDFVPTHRRLPGWMLSTLLHIVVLVGLALMMGQDSHGTGDAPDRPVGIAIVHRMPDRTEYETAAEQSQATEQAAASQAASAAQGSQAALPADAAPPLDLDGLLAAALDTPLPAGNPGESDAMQAAAASAGKPGMNLGPSGSQHTTEVFGISGTGSRFVYVFDRSESMNGFGGRPLLAAKMQLVRSIDSLGPEQEFQIIFYNNQPRPFVPGGQIVRLLNGDEQTKRSAEQYVRAMTAFGGTRHMDALLMALRMSPDVIFFLTDARIPRLNGAQLQEIKARAQRSGTTIHTIEFGDDLEPPRDSFLRNLATDNGGQYRYLHVGALDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVJ4</accession>
    <name>A0A518IVJ4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_31060</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="entry name" value="DUF4159"/>
    </dbReference>
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        <property type="entry name" value="Terpenoid_cyclase/PrenylTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13709">
        <property type="entry name" value="DUF4159"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48239">
        <property type="entry name" value="SSF48239"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021863233" evidence="1">
        <location>
            <begin position="21"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4159" evidence="2">
        <location>
            <begin position="344"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4159" evidence="2">
        <location>
            <begin position="581"/>
            <end position="773"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="775" mass="85723" checksum="B03EACBBF1CA3F6F" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVN8</accession>
    <name>A0A518IVN8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">AAA domain (Dynein-related subfamily)</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">Mal33_31630</name>
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    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetia</taxon>
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            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011704">
        <property type="entry name" value="ATPase_dyneun-rel_AAA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07728">
        <property type="entry name" value="AAA_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_5" evidence="1">
        <location>
            <begin position="91"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="374" mass="40555" checksum="3E00979EA8681D1D" modified="2019-10-16" version="1">MAKKAAQPKKKASNDDRMLRRPAEDLFAEEIDALIKNDQYPCPNGWRMSARSVLTYICGGKAGSTPITPKYVGNRRLVEIAISTLVTDRALLLIGEPGTAKSWLSEHLAAAINGDSTKVVQGTAGTTEEQIRYTWNYAMLIAHGPSPEALIKSPVFRAMESGQLARFEEITRCASEVQDAMISLLSEKRISVPELATEVAAEKGFSVIATANTRDRGVNDMSAALKRRFNLVVLPSPSDLETEIDIVTGRVAQLASNLDLQAELPTPDAVEKVCTIFRELRSGETLDGKNKLKSPSGVLSTAEAISLLCNSMALAGSFGNGSVTAEDIAAGLQGSVVKDDDKDHLVWSEYLKNVMKKRGSQWRLLFDACSDHNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVW0</accession>
    <name>A0A518IVW0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_32300</name>
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    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="82" mass="8841" checksum="095700EB7F42CA1D" modified="2019-10-16" version="1">MVVLEEVPAANTIMLSDHVGERQVNSGSRYYSSPEIKVFAQLRSSFTQASEAARPLSIKRLDGATMLSRGAGEVATMEGILL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVZ7</accession>
    <name>A0A518IVZ7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Serine endoprotease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_32680</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S1C family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13180">
        <property type="entry name" value="PDZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022092839" evidence="2">
        <location>
            <begin position="28"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="3">
        <location>
            <begin position="175"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV57264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="353" mass="37575" checksum="7A1921A097FFE64F" modified="2019-10-16" version="1" precursor="true">MIRSNLARLMILALLATSTPAVQPAVAQPAVRKPLPSETLLPGYLRDRMLRRVASRRDSAAMTLLMQPLAVQAGSSTVEVLLGGQRVALGTVVTADGYLVSKASELKADGELRVRLADDRILPARRVDERRSVDLALLKVEAQSLVPISWNPHEPAVGSFLFSVGRQGDPVGIGVVSVASREVQDHGLLGVMLQTDTNGARVISVVPGSGADDAGIGVGDLITQVEGQPMTTQKQVTAELRALYPGDSVTLTIRRKDRQDDFELSAEIRELSSFSESQDDTRVNGPRNSRLAGFELALQHDTVLGPDQCGGPVIDTNGRVIGINIARAGRVCSYAVPAAAIQPIVDQMIAATK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWD7</accession>
    <name>A0A518IWD7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glutamine synthetase</fullName>
            <ecNumber evidence="3">6.3.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">glnII</name>
        <name evidence="5" type="ORF">Mal33_34060</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>ATP + L-glutamate + NH4(+) = ADP + H(+) + L-glutamine + phosphate</text>
            <dbReference type="Rhea" id="RHEA:16169"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.1.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the glutamine synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.1.2" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004356">
        <property type="term" value="F:glutamate-ammonia ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006542">
        <property type="term" value="P:glutamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008147">
        <property type="entry name" value="Gln_synt_b-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036651">
        <property type="entry name" value="Gln_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008146">
        <property type="entry name" value="Gln_synth_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027303">
        <property type="entry name" value="Gln_synth_gly_rich_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027302">
        <property type="entry name" value="Gln_synth_N_conserv_site"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00120">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03951">
        <property type="entry name" value="Gln-synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01230">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54368">
        <property type="entry name" value="SSF54368"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="SSF55931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00180">
        <property type="entry name" value="GLNA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00181">
        <property type="entry name" value="GLNA_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 5" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gln-synt_C" evidence="4">
        <location>
            <begin position="88"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV57396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="341" mass="37810" checksum="3C75CB09B5D2A073" modified="2019-10-16" version="1">MTKCKLEYVWLDGYQPTQLLRSKTKIEDDFSGNVEDAKMWSFDGSSTEQATGGKSDLLLKPVKVIPDPGRIGTGFLVMCEVLNPDGTPHKTNGRATIADDDGDFWFGFEQEYTLWDSETQKPVGFPEQGFPAPQGPYYCSVGGGRAVGREIVEEHLEMCLQAGLNVEGINAEVMLGQWEFQIFAKGARDAGDQIWLARYLLDRTAESHGVEINYHCKPVKGDWNGSGMHANFSNSLLRTCGSQEVYEAVCKAFEPRIKEHIDVYGADNDQRLTGLHETQSIDKFSYGVSDRGASIRIPIFTVEHGWKGWLEDRRPASNADPYMVASAIIATVKSAKLPVNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWK7</accession>
    <name>A0A518IWK7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lactate utilization protein C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">lutC</name>
        <name evidence="2" type="ORF">Mal33_34810</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024185">
        <property type="entry name" value="FTHF_cligase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003741">
        <property type="entry name" value="LUD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02589">
        <property type="entry name" value="LUD_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LUD_dom" evidence="1">
        <location>
            <begin position="106"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="210" mass="22914" checksum="5622EA750ACE9482" modified="2019-10-16" version="1">MGSKARDSRQAILDRLRSREVTPVELPAIFGDDSISQVAIGFDDPPTQFAGTVEAVGGLCLQVGSTQEALNKLEQDEVYRDAARRCSLVGDEIPGNVNLQEIEDPHDLSSLDFLIARAEFGVAENGAMWITDRDIRHRASLFITQHLALVVSRQSIISNMHQAYERIGQPETPFGVFIAGPSKTADIEQSLVLGAHGCRTLTVFLVDEPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWL1</accession>
    <name>A0A518IWL1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">zinc_ribbon_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_34940</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026870">
        <property type="entry name" value="Zinc_ribbon_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13240">
        <property type="entry name" value="zinc_ribbon_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="domain" description="zinc_ribbon_2" evidence="2">
        <location>
            <begin position="19"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="102" mass="11660" checksum="8368990B86498BF6" modified="2019-10-16" version="1">MFAKWFRRSRRPVVDRTPCPHCGAMILETATFCRHCGASDASGWQDETEGYADDMADDDFDYDEFLQREFPDDAPPRRDFKSFVIIVLLICFVGGLLLSLGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWM6</accession>
    <name>A0A518IWM6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ATP-binding protein Uup</fullName>
            <ecNumber evidence="5">3.6.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 9" type="primary">uup</name>
        <name evidence="9" type="ORF">Mal33_34750</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="5">Associates with ribosomes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.-" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00848">
        <property type="entry name" value="Uup"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032524">
        <property type="entry name" value="ABC_tran_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032781">
        <property type="entry name" value="ABC_tran_Xtn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043686">
        <property type="entry name" value="Uup"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037118">
        <property type="entry name" value="Val-tRNA_synth_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16326">
        <property type="entry name" value="ABC_tran_CTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12848">
        <property type="entry name" value="ABC_tran_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="4"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="289"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="502"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="575"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="502"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="518"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5 6">
        <location>
            <begin position="36"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5 6">
        <location>
            <begin position="321"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV57465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="602" mass="67043" checksum="243EBB3A0E4BB92E" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWS7</accession>
    <name>A0A518IWS7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Mal33_35540</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011743">
        <property type="entry name" value="Caa3_sub_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005171">
        <property type="entry name" value="Cyt_c_oxidase_su4_prok"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03626">
        <property type="entry name" value="COX4_pro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02229">
        <property type="entry name" value="caa3_sub_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="18"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="49"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="77"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV57544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="115" mass="13196" checksum="50B8527206AE14E7" modified="2019-10-16" version="1">MSSHSEHDDGEFAHPMPIWMLLAVFFALTALTFITVFQASLHLGNWEIWIAMTIASVKATLVMAFFMHMLWDKPFNILMFLSSFLFVTLFVSFLLMDTHAYNHNVIVKPVGEVVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWV6</accession>
    <name>A0A518IWV6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_35780</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0047 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.460">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001602">
        <property type="entry name" value="UPF0047"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035917">
        <property type="entry name" value="YjbQ-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30615">
        <property type="entry name" value="PTHR30615"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01894">
        <property type="entry name" value="UPF0047"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004681">
        <property type="entry name" value="UCP004681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111038">
        <property type="entry name" value="SSF111038"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00149">
        <property type="entry name" value="TIGR00149_YjbQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01314">
        <property type="entry name" value="UPF0047"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="120" mass="13135" checksum="EBC0ED87B05D2CC7" modified="2019-10-16" version="1">MTREILSALPELAEVQVGLLHVFIQHTSASLTINENADPDVRTDFEMVANHLVPESLPYVHTLEGSDDMPAHVKGALMGFSLSIPISSGQLALGTWQGIYLCEHRNHGGRRQLVLTVHGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWW4</accession>
    <name>A0A518IWW4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Cycloserine biosynthesis protein DcsG</fullName>
            <ecNumber evidence="1">6.3.3.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">dcsG</name>
        <name evidence="1" type="ORF">Mal33_35910</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="6.3.3.5" evidence="1"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="294" mass="32883" checksum="FA712B4EAC838B29" modified="2019-10-16" version="1">MPRCAFLTLANQDGWLIDDYLVHEPLRQLGWEIVDLAWDGDVDWNTFDVVVIRSTWDYQYALDRFLAVLKQIDESKATLCNSLATVRWNADKCYLFDLQRRGIEAAATQHVMSPTPDDIQNALVRFDAPQIVIKPTVGAGSVDTFRITPATPLEDLASHCETLAGRSCFIQPFMDGITAEGEFSLIYIDGQLSHTILKTVRDGDFRVQSQHGGGVTFIPEPEAALVAAADRVIAALDEVPLYARVDLVRTQQESFALMELELIEPRLYFEFAEHSPQLFANAIARRSTQNSSGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWY6</accession>
    <name>A0A518IWY6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_36170</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="71" mass="7949" checksum="A79B9822250CDE6B" modified="2019-10-16" version="1">MVTQTGGGIEFLKAAETGRDRVPTGTRESKTVQQRKTKDLLCDGQLQFFAQLFQTAEVFLKRHLGFDTGFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IX35</accession>
    <name>A0A518IX35_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_36620</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="399" mass="44306" checksum="3F6C5513E1E82D92" modified="2019-10-16" version="1">MNRWTILLMVATLANACDADVVYLRGGGSLSGSVKSLEMGKQKVIVVDTGNGIQISLTQGEVARVDRENDLIAQYQAHRATAGEDADAHWELARWCKANSLLPQYDRQVRHVIRLNPQHPTARASLGYTSVNGKWVLHDELQRAHGLVRHLGKWKVPADVEMTEAEAELEIQQKQWIQTVKRLRGRVLKGGKAADESLVELTAIEDPLASGAIGKLLVQREDPDSLRMLWVKLLSKWETAEAADALIMASLFDPEPMIREACLDRLEQFAKTRAVNTYIAMLRDNDNKKVRIAANALMAMKDPRSILPLTDALVTTHKSKTGGGPSMSSSFDRNGGGGGGFSFGGGKEKIIEQKVRNPPVLSALMTLAPDADYQYDAERWRQHFSRQMAEVSYDLRRDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXE8</accession>
    <name>A0A518IXE8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Planctomycete cytochrome C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Mal33_37620</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011429">
        <property type="entry name" value="Cyt_c_Planctomycete-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011444">
        <property type="entry name" value="DUF1549"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022655">
        <property type="entry name" value="DUF1553"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07635">
        <property type="entry name" value="PSCyt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07583">
        <property type="entry name" value="PSCyt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07587">
        <property type="entry name" value="PSD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022166599" evidence="2">
        <location>
            <begin position="23"/>
            <end position="1072"/>
        </location>
    </feature>
    <feature type="domain" description="PSCyt1" evidence="5">
        <location>
            <begin position="37"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="PSCyt2" evidence="3">
        <location>
            <begin position="151"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="domain" description="PSD1" evidence="4">
        <location>
            <begin position="795"/>
            <end position="1034"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="430"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="733"/>
            <end position="760"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV57748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1072" mass="119388" checksum="5ABC0D62B8A5BC83" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXF3</accession>
    <name>A0A518IXF3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Branched-chain alpha-keto acid dehydrogenase subunit E2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_37860</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="259" mass="29292" checksum="C3B86BFE6F441AB0" modified="2019-10-16" version="1">MAKMKKGHWRSLSKNRRLVLDVCAISRRMPLFPAERNVDLSQVAQARSESPSRVSWAAIFTKAFALAAADQPQLRQTYYRLPWPHLYEHNHSVASIAMHRFDGEEDRLCWARIRRVEEQTLAEIQRQLDDFKSQPIEVAFRSQHRLSRMPMPIRRLVWGLALNFSGRSRAKEVGTFSMSSVAGLGTYNRFHPTVLSSSLSYGPIDDDGNCLVTLICDHRVIDGYRAGICLQQIEAMLAGPIAEELRQMAESAPAAARAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXH9</accession>
    <name>A0A518IXH9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">F5/8 type C domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Mal33_38080</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011429">
        <property type="entry name" value="Cyt_c_Planctomycete-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011444">
        <property type="entry name" value="DUF1549"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022655">
        <property type="entry name" value="DUF1553"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07635">
        <property type="entry name" value="PSCyt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07583">
        <property type="entry name" value="PSCyt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07587">
        <property type="entry name" value="PSD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome c" evidence="5">
        <location>
            <begin position="26"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV57793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="990" mass="110655" checksum="EE4B427044FBA017" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXR5</accession>
    <name>A0A518IXR5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_38940</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="54" mass="5909" checksum="1FC74C5B4913FFC1" modified="2019-10-16" version="1">MNLLDLLFLHAAYMAGIFTVAILGAALVIRAQSDRVQPTAGGIHNHAERPQRIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXV0</accession>
    <name>A0A518IXV0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PINc domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_39360</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13470">
        <property type="entry name" value="PIN_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PINc" evidence="1">
        <location>
            <begin position="1"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="183" mass="20927" checksum="3AEAB6FF0003E424" modified="2019-10-16" version="1">MLDACVLYPAPLRDLLLSLAASGIYRAKWSQKIHDEWTHNLLLKRPDLDAERLRRTCVQMNLAVPDSLVTEYEALIDSLHLKDPDDRHVLAVAIRCNADSIVTFNQKDFDEAELKKYGLYTEHPDEFISNMLEVYTPNVLAAVREMRARLKNPPVEVAGFLETLRRQGLPQTVHILSRYASSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXX5</accession>
    <name>A0A518IXX5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">ATP synthase subunit c</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">ATP synthase F(0) sector subunit c</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">F-type ATPase subunit c</fullName>
            <shortName evidence="13">F-ATPase subunit c</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Lipid-binding protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13 15" type="primary">atpE</name>
        <name evidence="15" type="ORF">Mal33_39530</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12 13">F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.</text>
    </comment>
    <comment type="function">
        <text evidence="13">Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Cell membrane</location>
            <topology evidence="13">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the ATPase C chain family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045263">
        <property type="term" value="C:proton-transporting ATP synthase complex, coupling factor F(o)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01396">
        <property type="entry name" value="ATP_synth_c_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005953">
        <property type="entry name" value="ATP_synth_csu_bac/chlpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000454">
        <property type="entry name" value="ATP_synth_F0_csu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020537">
        <property type="entry name" value="ATP_synth_F0_csu_DDCD_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038662">
        <property type="entry name" value="ATP_synth_F0_csu_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002379">
        <property type="entry name" value="ATPase_proteolipid_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035921">
        <property type="entry name" value="F/V-ATP_Csub_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00137">
        <property type="entry name" value="ATP-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00124">
        <property type="entry name" value="ATPASEC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81333">
        <property type="entry name" value="SSF81333"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01260">
        <property type="entry name" value="ATP_synt_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00605">
        <property type="entry name" value="ATPASE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 13" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="13" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 13" id="KW-0138">CF(0)</keyword>
    <keyword evidence="6 13" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="8 13" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 13" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 13" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="59"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-synt_C" evidence="14">
        <location>
            <begin position="17"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="site" description="Reversibly protonated during proton transport" evidence="13">
        <location>
            <position position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="QDV57937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="81" mass="8230" checksum="3BF2EC836828810D" modified="2019-10-16" version="1">MLDFMMLLAQSSELGKMGAGLGMGLVILGASLGIGRIGGNAVDAIARQPEAGGRIGTNMLIACALIEGVTVIALILEYILN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXZ3</accession>
    <name>A0A518IXZ3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phosphate-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">pstS_3</name>
        <name evidence="5" type="ORF">Mal33_39700</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the PstS family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042301">
        <property type="term" value="F:phosphate ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035435">
        <property type="term" value="P:phosphate ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005673">
        <property type="entry name" value="ABC_phos-bd_PstS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024370">
        <property type="entry name" value="PBP_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12849">
        <property type="entry name" value="PBP_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002756">
        <property type="entry name" value="PstS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00975">
        <property type="entry name" value="3a0107s03"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PBP_domain" evidence="4">
        <location>
            <begin position="38"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR002756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF12849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV57954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="353" mass="37422" checksum="ADAC3DE9095433AE" modified="2019-10-16" version="1">MRWRNSSVFVAGLTACLLFSGCSSRSSDSSGGADAADNVKLTGSGASFPFPLYDRWFKEYSRAHDGVQIDYQAKGSGAGIKDFTNGTVDFGASDAAMSDEEIAAVGAGVQLLPMTAGEVVLAYNLPGVEGLKLSREAYTGIFLGKVTNWTDPLIADANPGAKLPDEDITVVRRADSSGTTFVFTQHLSAISEAWANGPGTGKTVVWPDSDKIVASPKNDGVTATITQTPGAIGYIEYGYAKLTKLAMASLENKAGNFVMPSLESGQAALSNVEMPADLRAWLPDPPGDQAFPIVSYTWLLCYKKYEDPKQAEALKAVVKYCLTDGQKISDEMGYVPLPEDVVAKVTAALDAIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYD4</accession>
    <name>A0A518IYD4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">HTH-type transcriptional regulator UlaR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ulaR</name>
        <name evidence="5" type="ORF">Mal33_41140</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014036">
        <property type="entry name" value="DeoR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001034">
        <property type="entry name" value="DeoR_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018356">
        <property type="entry name" value="Tscrpt_reg_HTH_DeoR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00455">
        <property type="entry name" value="DeoRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08220">
        <property type="entry name" value="HTH_DeoR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00037">
        <property type="entry name" value="HTHLACR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00420">
        <property type="entry name" value="HTH_DEOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00894">
        <property type="entry name" value="HTH_DEOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51000">
        <property type="entry name" value="HTH_DEOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH deoR-type" evidence="4">
        <location>
            <begin position="7"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV58097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="260" mass="28409" checksum="1A17E27FAF387135" modified="2019-10-16" version="1">MSNGSPTEARRENLRRQIQATGFASLLELAAELQVSESTIRRDLDYLEELGEARRTHGGVFWTGSPTNMRLFEGRRDNRWEQKRAIAQAASQLIGDSDTIILDGGSTTYELARLLVGRPLQVVTNSLPVANLFASSDKSDLVLVGGYVHNRTGVTLGPFANTMLESLNVRHAVISIAGADERGYYNSNMLLVGTEKEMLRSADETIIVADSTKFGHASLSRTCQLGDVATVVTDDELSPQWQQRLTDAGVQLIIAPALHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYE0</accession>
    <name>A0A518IYE0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Ethanolamine utilization protein EutN/carboxysome</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_41240</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031469">
        <property type="term" value="C:bacterial microcompartment"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01614">
        <property type="entry name" value="EutN_CcmL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004992">
        <property type="entry name" value="EutN_CcmL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036677">
        <property type="entry name" value="EutN_CcmL_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36539">
        <property type="entry name" value="PTHR36539"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03319">
        <property type="entry name" value="EutN_CcmL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF159133">
        <property type="entry name" value="SSF159133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51932">
        <property type="entry name" value="BMV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="94" mass="10033" checksum="62A071E87242BED2" modified="2019-10-16" version="1">MRIAKVIGSVTLSRCHPAMAGSRLRCVLPVDDIAQIDSDDFSGSELLVTWDELGAGNGDLIALAEGPEAAQPFQPQIKCIDAYNAAILDHIDLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYE4</accession>
    <name>A0A518IYE4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Acetate kinase</fullName>
            <ecNumber evidence="6">2.7.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Acetokinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 8" type="primary">ackA</name>
        <name evidence="8" type="ORF">Mal33_41190</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>acetate + ATP = acetyl phosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:11352"/>
            <dbReference type="ChEBI" id="CHEBI:22191"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="6">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="6">Mg(2+). Can also accept Mn(2+).</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the acetokinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.1" evidence="6"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00340">
        <property type="reaction ID" value="UER00458"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008776">
        <property type="term" value="F:acetate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006085">
        <property type="term" value="P:acetyl-CoA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006082">
        <property type="term" value="P:organic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00020">
        <property type="entry name" value="Acetate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004372">
        <property type="entry name" value="Ac/propionate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000890">
        <property type="entry name" value="Aliphatic_acid_kin_short-chain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023865">
        <property type="entry name" value="Aliphatic_acid_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21060">
        <property type="entry name" value="PTHR21060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00871">
        <property type="entry name" value="Acetate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000722">
        <property type="entry name" value="Acetate_prop_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00471">
        <property type="entry name" value="ACETATEKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00016">
        <property type="entry name" value="ackA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01075">
        <property type="entry name" value="ACETATE_KINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6 7" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="6">
        <location>
            <position position="7"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="14"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="278"/>
            <end position="280"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="379"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="6">
        <location>
            <position position="178"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="6">
        <location>
            <position position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV58102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="393" mass="42216" checksum="33241B4935FE7A1F" modified="2019-10-16" version="1">MKVLVANLGSTSFKYQLIEMSDETTLARGAVDRIGSPESSCTVEIGDWKDQRTMSVPHHGVAVEACLQQLTDPDHGCIKSADEVDAIGFKAVHGGRFSGVYRIDEEVLAAMEEMRDVAPAHNPPYVAAMRQLASSGGNIPLIAAFETDFHQTTPDAQRYYAIPKQWSDDFHIRRFGFHGNSHRYIAMRTAELIPGASRVISCHLGGSSSLCAIRDGKSIGTTMGMSPQTGLPQNNRVGDFDPFAIPLIMEKTGLSLTEVLNKLANEGGLLGLSGKSGDMRDLEAGAAEGDADCQLALDVYVSEVRRMMGGLLVLLGGADAIVFTGGIGEKGAEIRAKVCEGLEDLGIAIDRVKNGVAEGEMAVHSETSRTQIWRIPTNEELVVARKCVELLGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYE5</accession>
    <name>A0A518IYE5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 6">Phosphate propanoyltransferase</fullName>
            <ecNumber evidence="3 6">2.3.1.222</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">pduL</name>
        <name evidence="7" type="ORF">Mal33_41150</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>phosphate + propanoyl-CoA = CoA + propanoyl phosphate</text>
            <dbReference type="Rhea" id="RHEA:28046"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57392"/>
            <dbReference type="ChEBI" id="CHEBI:58933"/>
            <dbReference type="EC" id="2.3.1.222"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="6">Polyol metabolism; 1,2-propanediol degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the PduL family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.222" evidence="3 6"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00621"/>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051144">
        <property type="term" value="P:propanediol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008300">
        <property type="entry name" value="PTAC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39453">
        <property type="entry name" value="PTHR39453"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06130">
        <property type="entry name" value="PTAC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF010130">
        <property type="entry name" value="PduL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 7" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR010130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV58098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="239" mass="25669" checksum="122F8E9FE7BF6418" modified="2019-10-16" version="1">MTQSLDNAQIEALVRRAVRAIVNNDSTSAAQPPGWVDGKPNLRVSISARHVHLSDEHVETLFGPGATLTPMKDLYQDGFFAAEQTVMIIGPKKRMLPSVRVLGPTRPFSQVELAFTDSISLGLDIPIRHSGDIEGTPGCVLVGPAGTIQLDKGVIRAARHVHMNQSDAQYFGVKKGDFMDLKITSPQCTITMSDVLVRADETSKLEVHIDTDEGNACNLDSATKIELIPSGGGCGCKAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYP0</accession>
    <name>A0A518IYP0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 4">Biotin carboxyl carrier protein of acetyl-CoA carboxylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">accB</name>
        <name evidence="6" type="ORF">Mal33_42230</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 4">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009317">
        <property type="term" value="C:acetyl-CoA carboxylase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003989">
        <property type="term" value="F:acetyl-CoA carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001249">
        <property type="entry name" value="AcCoA_biotinCC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001882">
        <property type="entry name" value="Biotin_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01071">
        <property type="entry name" value="ACOABIOTINCC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00531">
        <property type="entry name" value="BCCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00188">
        <property type="entry name" value="BIOTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0092">Biotin</keyword>
    <keyword evidence="4" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="4" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="5">
        <location>
            <begin position="76"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU364072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV58206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="155" mass="16066" checksum="832401009BED2945" modified="2019-10-16" version="1">MSGDVFDIEQIRKLVELMEEHNLAEVDLKQDQKTIKLCRGGFAAAPAPMMVPQAVAPAAPAAAPAAAAPAADGANIAIIKAPMVGTFYARANPEASPFVSVGDSVNADTTICIVEAMKVFNEIPAEISGKVVAILAKDGEAVDFGKPLFKIDTSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYY4</accession>
    <name>A0A518IYY4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_43050</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="145"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="441" mass="48144" checksum="ACAC039FE301F89B" modified="2019-10-16" version="1">MNAASEQPQFDPYHQWLGIPPDQQPANLYRLLGLERFESDADVIDVAANRQIAYLRQVGVGAKRDPAKRLVAELADARRVLLNPPLRKAYDHQLIASSAPQTDDLENPSPDRQPAASETIRHGPSLRIPTRPPQKHSRRKRQRKFALGGTAILTVLVVVGGGYLATRGPTTIATPATKTVTAKVDPAAPRRHVVHKPIIAGVPKPPRHVASDPKTRSLTDVFDQKFRSAQQATPAATSSPDKQADSLPILVDFEGDAWLAALAIDDLALFNQHHSVRDGKLFVLQAEDESYIGTPLRLKNVKLKAEQSLAVDARIPKGLKHNSGVALQAADFTLALRVDSRSTLLAGTVRSGVSIELASIPYESDPQGLQQPYRLRITCPPADSTTYSWRIDVPSGEAVEGTFAAEQTMTGGEAIVRAWRYDARNSHFWIDNLASDTLDAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ39</accession>
    <name>A0A518IZ39_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Signal peptide peptidase SppA</fullName>
            <ecNumber evidence="2">3.4.21.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">sppA</name>
        <name evidence="2" type="ORF">Mal33_43710</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.4.21.-" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07023">
        <property type="entry name" value="S49_Sppa_N_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002142">
        <property type="entry name" value="Peptidase_S49"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01343">
        <property type="entry name" value="Peptidase_S49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_S49" evidence="1">
        <location>
            <begin position="96"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="302" mass="33203" checksum="31EEE723146E1AB8" modified="2019-10-16" version="1">MQPQVLRDRSPLKTMPVQAGSCRKIALIDVDGLLVNQNQAGIGSMGDNPLDIFREKLDQVEREGDISAVIIRINSYGGGVTASDIMRRELEAFRERTGMPIVAVLMDIATGGGYLLATAADQIVAHPTTIVGGFGVILNLYNLEDAMAQFNVAGQTIRAGKFVDIGSPERFLEEDEEELLTEIAEQYNARFKEVVLRSRQRIHPDVEIFDGRIFTGTKAEKLGVVDQVGYIDDAIAAARAYAGDPNACVVMLHREQDKARTPYATTPNEPTQLMAMPQIPGLMRSRLPTFMYIWQPDPGLAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ79</accession>
    <name>A0A518IZ79_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_44090</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021215">
        <property type="entry name" value="DUF2752"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10825">
        <property type="entry name" value="DUF2752"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="110"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="155" mass="17030" checksum="66F5816AEEA746F8" modified="2019-10-16" version="1">MASPIQRSPVPADRRLRIGLAIAAVATIAASAVVLHRFEPNANSWYPKCPLHEMTGLHCPGCGTTRAAREILHGDLATAVQLNPLTVIGGPIFLMMLWRNRRRRQAGKPTKPLLGWAFLVLLILYFVARNVPSPTRSWFAPPSPQPTIAEPTTPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZG7</accession>
    <name>A0A518IZG7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_45090</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="54" mass="5797" checksum="80F61273B30DE29F" modified="2019-10-16" version="1">MGESLSWPLLDTKGGTGALMLLRLHAIRTFPLLPPGAILGKLLATINGHYSNLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZH6</accession>
    <name>A0A518IZH6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_45140</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="190" mass="21882" checksum="127BF68432C8E089" modified="2019-10-16" version="1">MVEKIPVFDRNGLLPVGDYDVSLFDLRGSVLCRGPDDRQAYPNWDSAWRVWLVEQLAIMAQQLWQVGVESIFVDGSFVEDKDHPNDIDGYFVCDRDEFVSGRLVAALNRLDPQKVWTWDHSLRRAYPGYPKKQLPMWHVYRVELYPHFSGLGSGIRDARGNELEFPAAFRQCRRDGKPKGIVRLLKVTGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZI3</accession>
    <name>A0A518IZI3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_45330</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022027485" evidence="2">
        <location>
            <begin position="30"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="444" mass="48162" checksum="60C57163818C69F6" modified="2019-10-16" version="1" precursor="true">MNTREKFKSPTLHRLLVLLICLPAGVASAQPPENEAVPAAGQASPSEPAAPVDDEQPAAGSDTKAADKKGAVKEVTVLTAADRQRIDALIADLSSSKFAIREEAVAGLIEFGERAIPMLAAAADTPDPEVQLRIRILMSRLSNNDFESAVMAFLSGASDEMEGWDYARRLIGDSNAARELFVDASRQHRELMEELDKGPGLRMVAANKAADLVVRRMMLEFLPPERGDAVALLLTCGDRSAPIPPGVERVIVRIMNSPVTSETLKDAMLAPVYQKLVGFWMRRASVSYQPQAMYFALQHRVPESVELARDIVAEFVAAGEELTGPEIIDPKYGEGLEQALLVIAKYGDPSDVARLEPLRNDARRMPIGTDQPGDTHDRIEIQVRDIAVAVSIKILGGDLREAGYLNPREHAIVVFFTASLGFPGGGDELRSKPAKYLADLIAKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZW3</accession>
    <name>A0A518IZW3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Deoxyribose-phosphate aldolase</fullName>
            <shortName evidence="3">DERA</shortName>
            <ecNumber evidence="3">4.1.2.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">2-deoxy-D-ribose 5-phosphate aldolase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Phosphodeoxyriboaldolase</fullName>
            <shortName evidence="3">Deoxyriboaldolase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">deoC2</name>
        <name evidence="3" type="synonym">deoC</name>
        <name evidence="4" type="ORF">Mal33_46530</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 3">
            <text>2-deoxy-D-ribose 5-phosphate = acetaldehyde + D-glyceraldehyde 3-phosphate</text>
            <dbReference type="Rhea" id="RHEA:12821"/>
            <dbReference type="ChEBI" id="CHEBI:15343"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="ChEBI" id="CHEBI:62877"/>
            <dbReference type="EC" id="4.1.2.4"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Carbohydrate degradation; 2-deoxy-D-ribose 1-phosphate degradation; D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-alpha-D-ribose 1-phosphate: step 2/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.4" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00002">
        <property type="reaction ID" value="UER00468"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004139">
        <property type="term" value="F:deoxyribose-phosphate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016052">
        <property type="term" value="P:carbohydrate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009264">
        <property type="term" value="P:deoxyribonucleotide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046386">
        <property type="term" value="P:deoxyribose phosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00959">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00114">
        <property type="entry name" value="DeoC_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011343">
        <property type="entry name" value="DeoC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002915">
        <property type="entry name" value="DeoC/FbaB/LacD_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028581">
        <property type="entry name" value="DeoC_typeI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10889">
        <property type="entry name" value="PTHR10889"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10889:SF1">
        <property type="entry name" value="PTHR10889:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01791">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001357">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01133">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00126">
        <property type="entry name" value="deoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 4" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0704">Schiff base</keyword>
    <feature type="active site" description="Proton donor/acceptor" evidence="3">
        <location>
            <position position="94"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with acetaldehyde" evidence="3">
        <location>
            <position position="158"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="3">
        <location>
            <position position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV58629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="241" mass="26413" checksum="743F5E10ED3D9576" modified="2019-10-16" version="1">MDYRYEEIAKMLDHSLLQPFLKTETLEAGISLALAYDVASVCILPYYVKRCADRLAGSTVQTSTTIGFPHGGHTTAIKAAEAQQAIDDGCQELDMVVNISKVLSGDWDYVTRDIKAVIDVAHAAGQKVKVIFENCYLDADQKSRLCAICSELGADWVKTSTGYGTGGATLEDLQLMREKSAPEVQVKAAGGVRDLDRLLEVRELGVTRVGASATQTILDECRRRLKLEPIDFDELKNTSSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J017</accession>
    <name>A0A518J017_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Xylose isomerase-like TIM barrel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_46590</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013022">
        <property type="entry name" value="Xyl_isomerase-like_TIM-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01261">
        <property type="entry name" value="AP_endonuc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="SSF51658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AP_endonuc_2" evidence="1">
        <location>
            <begin position="22"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="281" mass="30716" checksum="64B17CAB2B91CF27" modified="2019-10-16" version="1">MEKWPIGVFASVDAGLGVRWEVIKELGVPTIQLHAPAAETRTQANADKLRSQMEEMSVELTAVFGGFEGESYADIPTVVETVGLVPEATRAARLQEMKEIADFAKLIECDVVALHLGFVPHETSDPSYEGIVTVMRDLCDHAANNGQRVHLETGQETADGLLQFLSSVERDNLFVNFDPANMILYGTGEPIPALQKVGSFVRSVHCKDGTWSDKPGETWGAEVPLGEGQVDMRKYLQTLNEIGYTGPLTIEREIPAEPERQLKEIGAAVALLTKLKSELLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J082</accession>
    <name>A0A518J082_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_47670</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="82" mass="9294" checksum="BF3C7183B647D242" modified="2019-10-16" version="1">MNETEHKTCFGKIFPRRVGSGDPMGKVFSIRNDESHGMIQSKPHIETDIKQWDACRKCPEFESCYQLSMATVAMETAVANHC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0C3</accession>
    <name>A0A518J0C3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Folylpolyglutamate synthase</fullName>
            <ecNumber evidence="6">6.3.2.17</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Mal33_48150</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="6.3.2.17" evidence="6"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004326">
        <property type="term" value="F:tetrahydrofolylpolyglutamate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001645">
        <property type="entry name" value="Folylpolyglutamate_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004101">
        <property type="entry name" value="Mur_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11136">
        <property type="entry name" value="PTHR11136"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02875">
        <property type="entry name" value="Mur_ligase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001563">
        <property type="entry name" value="Folylpolyglu_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01499">
        <property type="entry name" value="folC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mur_ligase_M" evidence="5">
        <location>
            <begin position="71"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_C" evidence="4">
        <location>
            <begin position="331"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV58790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="469" mass="51090" checksum="FF62268C80F7A6C0" modified="2019-10-16" version="1">MTQHDTNMPDDQQALSQDGWSYGQSLDYLYGRINYERLSKPSPGNPMKLNRMHALLAAMGDPQASLKIVHIGGTKGKGSTASMVAAIATQAGQRCGLYTSPHLESLEERFRVDGQPATQSQLISLIQSVRQAAETIRRQGEGEATFFELTTAMAIEHFRRDGCEVAVLEVGLGGRLDCTNICSPEVTAITSIGLDHQNLLGDTVEEIAAEKAGIIKPGVPVVSGVRDPAAAAVIQQIADERQAPLLQIDRDYHVQRESVAGNNPSRFDFLPSESAPLPLKRRTAWPLALAGIHQARNAAVALAITDCWNLKTQSLQWPEQACREALATLSVPGRIEFFPGEPLVILDTAHNRDSVEALADVLAERFESQNVVAVFGTSHDKDASEMLTILARNVKQIVLTRYRTNPRWYPPQDLAAIASRVAGQSWEVVENSHDALQVARHRAGPAGVVVVCGSFFLAAELRRSLVERS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0G5</accession>
    <name>A0A518J0G5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 8">Methionyl-tRNA formyltransferase</fullName>
            <ecNumber evidence="4 8">2.1.2.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8 11" type="primary">fmt</name>
        <name evidence="11" type="ORF">Mal33_48610</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 8">Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>(6S)-10-formyltetrahydrofolate + L-methionyl-tRNA(fMet) = (6S)-5,6,7,8-tetrahydrofolate + H(+) + N-formyl-L-methionyl-tRNA(fMet)</text>
            <dbReference type="Rhea" id="RHEA:24380"/>
            <dbReference type="Rhea" id="RHEA-COMP:9952"/>
            <dbReference type="Rhea" id="RHEA-COMP:9953"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:57454"/>
            <dbReference type="ChEBI" id="CHEBI:78530"/>
            <dbReference type="ChEBI" id="CHEBI:78844"/>
            <dbReference type="EC" id="2.1.2.9"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the Fmt family.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.9" evidence="4 8"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004479">
        <property type="term" value="F:methionyl-tRNA formyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd08646">
        <property type="entry name" value="FMT_core_Met-tRNA-FMT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08704">
        <property type="entry name" value="Met_tRNA_FMT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00182">
        <property type="entry name" value="Formyl_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005794">
        <property type="entry name" value="Fmt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005793">
        <property type="entry name" value="Formyl_trans_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002376">
        <property type="entry name" value="Formyl_transf_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036477">
        <property type="entry name" value="Formyl_transf_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011034">
        <property type="entry name" value="Formyl_transferase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044135">
        <property type="entry name" value="Met-tRNA-FMT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041711">
        <property type="entry name" value="Met-tRNA-FMT_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02911">
        <property type="entry name" value="Formyl_trans_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00551">
        <property type="entry name" value="Formyl_trans_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50486">
        <property type="entry name" value="SSF50486"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53328">
        <property type="entry name" value="SSF53328"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00460">
        <property type="entry name" value="fmt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Formyl_trans_N" evidence="9">
        <location>
            <begin position="10"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="Formyl_trans_C" evidence="10">
        <location>
            <begin position="212"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Tetrahydrofolate (THF) binding" evidence="8">
        <location>
            <begin position="114"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00016014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QDV58836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="322" mass="34568" checksum="90E94F8AC14AE417" modified="2019-10-16" version="1">MPDRPLTMVLMGTGPFAVPAFDAIRRSADSIALVVTRPEVISKSRKPAPPSPVRQWATDNELPIYDPPSINDVDAVAKLQALQADLFVVCDYGQILSSHALEAAVMGGINLHGSLLPSYRGAAPVQWAVWNGDPESGVSVIHMTPRLDGGPVIASATTPIQATETAGELEHRLSQLGVQPTLDAIQTLRNWDRESTIGVPQDKSLVSKAPRLAKADGRIDWSKSLREIDCHVRAMQPWPDAFTLVETGAKQPLRLVIRQLVASEHPRPADAQPGQVIVADGRLIVAAGDGCVEILRLVPAGKREMAAAEFMRGNPLPADAIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0H9</accession>
    <name>A0A518J0H9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8 10">FAD:protein FMN transferase</fullName>
            <ecNumber evidence="2 8 10">2.7.1.180</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Flavin transferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">apbE_3</name>
        <name evidence="11" type="ORF">Mal33_48630</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8 10">
            <text>FAD + L-threonyl-[protein] = AMP + FMN-L-threonyl-[protein] + H(+)</text>
            <dbReference type="Rhea" id="RHEA:36847"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11061"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:74257"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.7.1.180"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="9">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="9">Magnesium. Can also use manganese.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8 10">Belongs to the ApbE family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.180" evidence="2 8 10"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017013">
        <property type="term" value="P:protein flavinylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024932">
        <property type="entry name" value="ApbE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003374">
        <property type="entry name" value="ApbE-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30040">
        <property type="entry name" value="PTHR30040"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02424">
        <property type="entry name" value="ApbE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006268">
        <property type="entry name" value="ApbE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143631">
        <property type="entry name" value="SSF143631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0274">FAD</keyword>
    <keyword evidence="4 8 10" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="11" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="7 8 9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8 10" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="9">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="303"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="307"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR006268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR006268-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QDV58838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="358" mass="38654" checksum="01772CF7D5C84464" modified="2019-10-16" version="1">MLKRSDSVLLLPLLLAATLLVVGCERPAAEAVAEAKPVEILQSAGKTMGTRYEVKIANPPAELPADWQLLIDRELRRVNDQMSTYIATSEISRFNSSDSSDWFDVSAETANVVAAALEISGKTDGAFDVTVGPLVNLWSFGPEQHEKSVPDQAALDAAAAVTGYQSLHVRTDPPAIRKDKPGLQVDLSSIAKGHGVDRIVDLLQGLGCKNVFVNIGGEIRAIGDKGKDRPWRAGVERPDEATTVLLFPVAIEDDAIATSGDYRNFFEIDGKRYSHTIDPRTGRPIEHTLAAVSVVADNCMLADGWATALNVLGPVEGPRIAAAESIDAYLLERADGQFRPHPVGRFVQWSKPPVTQQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0J1</accession>
    <name>A0A518J0J1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">RNA 2'-phosphotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_48910</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002745">
        <property type="entry name" value="Ptrans_KptA/Tpt1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042080">
        <property type="entry name" value="RNA_2'-PTrans_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01885">
        <property type="entry name" value="PTS_2-RNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="83" mass="9401" checksum="AB7D473B4436D338" modified="2019-10-16" version="1">MNKRLTKICKYLTFVLRHHPEAIGIQLEPYGWVEIDKLVQNANAAGKSITREHVQQVVEQDEEKAFAISEDGMKIRAVLGPAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0J9</accession>
    <name>A0A518J0J9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">GMP synthase [glutamine-hydrolyzing]</fullName>
            <ecNumber evidence="9">6.3.5.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">GMP synthetase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Glutamine amidotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9 13" type="primary">guaA</name>
        <name evidence="13" type="ORF">Mal33_48500</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 9">Catalyzes the synthesis of GMP from XMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + H2O + L-glutamine + XMP = AMP + diphosphate + GMP + 2 H(+) + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:11680"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57464"/>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.5.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Purine metabolism; GMP biosynthesis; GMP from XMP (L-Gln route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homodimer.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.2" evidence="9"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00189">
        <property type="reaction ID" value="UER00296"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003922">
        <property type="term" value="F:GMP synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016462">
        <property type="term" value="F:pyrophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01742">
        <property type="entry name" value="GATase1_GMP_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01997">
        <property type="entry name" value="GMP_synthase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00344">
        <property type="entry name" value="GMP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001674">
        <property type="entry name" value="GMP_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004739">
        <property type="entry name" value="GMP_synth_GATase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022955">
        <property type="entry name" value="GMP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025777">
        <property type="entry name" value="GMPS_ATP_PPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022310">
        <property type="entry name" value="NAD/GMP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00958">
        <property type="entry name" value="GMP_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02540">
        <property type="entry name" value="NAD_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00884">
        <property type="entry name" value="guaA_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00888">
        <property type="entry name" value="guaA_Nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51553">
        <property type="entry name" value="GMPS_ATP_PPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 9" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="5 9 10" id="KW-0332">GMP biosynthesis</keyword>
    <keyword evidence="3 9 13" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 9 10" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GMPS ATP-PPase" evidence="12">
        <location>
            <begin position="229"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="9">
        <location>
            <position position="115"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="202"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="204"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="256"/>
            <end position="262"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="QDV58825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="546" mass="59853" checksum="A606E4432F289A3B" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1D8</accession>
    <name>A0A518J1D8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Methyltransferase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_51610</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018024">
        <property type="term" value="F:histone-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DOT1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026170">
        <property type="entry name" value="FAM173A/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13610">
        <property type="entry name" value="PTHR13610"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DOT1" evidence="4">
        <location>
            <begin position="64"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV59135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="223" mass="25723" checksum="BDCFF6482066DF87" modified="2019-10-16" version="1">MPTTALLKRVFSKRPTSTLQSVLSVYDDYLFDKRYRLETRSEVAINDLDISQEDKKHADKYKPTRSRYFRKIMEKVDLSREGVFVDVGCGKGRVLLLAAEHGFSQVLGLEISPALCRLADQNVQAFGKVCPNAESIKVICTNILDYQLDGSETVFFLYSPFDYSVTDRFLQMLRQSLEEHPRDLCLIIDEFRFPELLANDDYFQQTLTYKYGAAVFHVYSHVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1K2</accession>
    <name>A0A518J1K2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_52540</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005325">
        <property type="entry name" value="DUF308_memb"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03729">
        <property type="entry name" value="DUF308"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="144"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="170"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="197" mass="20689" checksum="B01D79D7036D2D01" modified="2019-10-16" version="1">MSSTNDSPAPVSTENPILNAIGSTWWILLLRGILLIVLGLYALFNPGLTLLAWAFMIGCFLIADGILAIVAGLAGWTESRGWTILRGVLALVAGGFAAGHPALIGTVAAVTVVLLIAAGSIFSGILEIVVAIRERKAIEGEGWMILDGVFSILFGIVLALAPLFSASLLIRFSGGFAILFGLVAIYCAFQFRKLKSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1L0</accession>
    <name>A0A518J1L0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">pknD_7</name>
        <name evidence="6" type="ORF">Mal33_52430</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
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    <feature type="domain" description="Protein kinase" evidence="5">
        <location>
            <begin position="182"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="110"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="341"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="110"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV59215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1435" mass="161185" checksum="C8B695E5339081A1" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1M5</accession>
    <name>A0A518J1M5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tetratricopeptide repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_52610</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001440">
        <property type="entry name" value="TPR_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="70"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV59233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="196" mass="21825" checksum="E8C6CC01B92D1FF3" modified="2019-10-16" version="1" precursor="true">MIWKTGAAVVAISWIGLWMTGDQHGDRLMRAEKFADAAVVYNDPMRQGVAWYRAGEFEKANQSFARVATPEAEFNQGNCWVMLGKYDKAVASYDQAIDQRPDWTQALENRDLAAARAKMLEQKGGDLGDQQVGADKIVFDKKKDDQGQETEIAGDQAASDATVQAVWLRQVQTKPADFLRSKFAFQQAEQDAGETQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1X5</accession>
    <name>A0A518J1X5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">GDP-mannose:cellobiosyl-diphosphopolyprenol alpha-mannosyltransferase</fullName>
            <ecNumber evidence="4">2.4.1.252</ecNumber>
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    </protein>
    <gene>
        <name evidence="4" type="primary">gumH</name>
        <name evidence="4" type="ORF">Mal33_53590</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.4.1.252" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
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        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025668">
        <property type="entry name" value="Tnp_DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13586">
        <property type="entry name" value="DDE_Tnp_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13579">
        <property type="entry name" value="Glyco_trans_4_4"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="61"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
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            <end position="342"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="366"/>
            <end position="513"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV59331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="548" mass="61185" checksum="5A633EB580BBAF0E" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J264</accession>
    <name>A0A518J264_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ketoacyl reductase</fullName>
            <ecNumber evidence="2">1.3.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">actIII_2</name>
        <name evidence="2" type="ORF">Mal33_54700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.-" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="339" mass="36579" checksum="BEE567F9537F4593" modified="2019-10-16" version="1">MNTFSKLALSAAIGYTGLKITRAVARRKRNFAWQNKRVVITGGSRGLGLVIARQLADQGARIAITARGEGDLAVAADELRDRGAEVISQTCDVRQPEQVTRFIDQVVQRYGGVDVLINVAGIITVGPLEAMEFDDFADSMNTNCWGALHTSKAVLPHMRSAGWGRIVNIASLGGKRAVPHMLPYAASKFALVGLSNGMRAELKQENIFVTTACPGLMRTGSPRNANFKGQHRDEYAWFSIGDSLPVMSMDAETAAMQILDACQQGRGEVFIHSPWNMTIALQNLCPELTQEILGLAATVLPKMGGIGRDSAKGHESQSAWSPSVLTTLTQRAAAMNNQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ILV6</accession>
    <name>A0A518ILV6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GTP cyclohydrolase 1</fullName>
            <ecNumber evidence="5">3.5.4.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">GTP cyclohydrolase I</fullName>
            <shortName evidence="5">GTP-CH-I</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">folE</name>
        <name evidence="7" type="ORF">Mal33_00050</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>GTP + H2O = 7,8-dihydroneopterin 3'-triphosphate + formate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17473"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:58462"/>
            <dbReference type="EC" id="3.5.4.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 5">Cofactor biosynthesis; 7,8-dihydroneopterin triphosphate biosynthesis; 7,8-dihydroneopterin triphosphate from GTP: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homopolymer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the GTP cyclohydrolase I family.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.16" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00848">
        <property type="reaction ID" value="UER00151"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003934">
        <property type="term" value="F:GTP cyclohydrolase I activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035998">
        <property type="term" value="P:7,8-dihydroneopterin 3'-triphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.286.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00223">
        <property type="entry name" value="FolE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043133">
        <property type="entry name" value="GTP-CH-I_C/QueF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043134">
        <property type="entry name" value="GTP-CH-I_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001474">
        <property type="entry name" value="GTP_CycHdrlase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018234">
        <property type="entry name" value="GTP_CycHdrlase_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020602">
        <property type="entry name" value="GTP_CycHdrlase_I_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11109">
        <property type="entry name" value="PTHR11109"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01227">
        <property type="entry name" value="GTP_cyclohydroI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00063">
        <property type="entry name" value="folE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00859">
        <property type="entry name" value="GTP_CYCLOHYDROL_1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00860">
        <property type="entry name" value="GTP_CYCLOHYDROL_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4 5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 5" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="GTP_cyclohydroI" evidence="6">
        <location>
            <begin position="15"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="155"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV54064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="193" mass="21323" checksum="4984CCB64BDB59F0" modified="2019-10-16" version="1">MNDKNSSRPVDLEAIKQAVRTILVAVGEDPDRAGLLETPRRVADMYAEMFSGLHIQPERHLEVTFPESYDEIVVVRDITFTSMCEHHLLPFSGTAHVAYLPNGCVTGLSKLARVVEEVSRRPQVQERMTQTIADMIEKHLNSSGVAVVIQAEHSCMSIRGVRKPGSETITSALRGVFKKNAASRAEVLSLIKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ILX7</accession>
    <name>A0A518ILX7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">6-carboxy-5,6,7,8-tetrahydropterin synthase</fullName>
            <ecNumber evidence="5">4.1.2.50</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Queuosine biosynthesis protein QueD</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Mal33_00060</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>7,8-dihydroneopterin 3'-triphosphate + H2O = 6-carboxy-5,6,7,8-tetrahydropterin + acetaldehyde + 2 H(+) + triphosphate</text>
            <dbReference type="Rhea" id="RHEA:27966"/>
            <dbReference type="ChEBI" id="CHEBI:15343"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18036"/>
            <dbReference type="ChEBI" id="CHEBI:58462"/>
            <dbReference type="ChEBI" id="CHEBI:61032"/>
            <dbReference type="EC" id="4.1.2.50"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Purine metabolism; 7-cyano-7-deazaguanine biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the PTPS family. QueD subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.50" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00391"/>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070497">
        <property type="term" value="F:6-carboxy-5,6,7,8-tetrahydropterin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007115">
        <property type="entry name" value="6-PTP_synth/QueD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038418">
        <property type="entry name" value="6-PTP_synth/QueD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01242">
        <property type="entry name" value="PTPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00018141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QDV54065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="154" mass="18073" checksum="FCB648DFAAE85C69" modified="2019-10-16" version="1">MIIQKEYKFYAAHRNEELYDKCRNLHGHRYGLRCFFEVKRSGALSTLFGDFDAKIEPYLKDQYDHGMLIHTGDSLYATLQDHMQRTGERFKLKVLDGPTSVENLAHKMFTEITEMGFRLQQLEVRETDTSVVTYTRDDWDEHNRDMAAEQAAAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IM54</accession>
    <name>A0A518IM54_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_01010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="QDV54155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="29" mass="3213" checksum="6C0D08EFE95AD5D7" modified="2019-10-16" version="1">MRLYAALGQHGVAQYTILGEEKTVVRHGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IM73</accession>
    <name>A0A518IM73_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_01380</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
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        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022218335" evidence="2">
        <location>
            <begin position="27"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="107"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="159" mass="15903" checksum="514646A34F7A8A9E" modified="2019-10-16" version="1" precursor="true">MYIHQFSYKCALAVVALLGASAIGCGSSGPQLEAVTGTITKDGVPFVGADLEFYPAGEGAASYGRSDENGNFTLRYSTGRPGAVPGEHLVTVIGGSVDASKLPAVPSDNAVASEGEPLAPIGNPDAAKKSGGPGGPPKSIDGIPATVVLGEENHVLIEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
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    <name>A0A518IM89_9BACT</name>
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        <submittedName>
            <fullName evidence="11">Photosystem I assembly protein Ycf3</fullName>
        </submittedName>
    </protein>
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        <name evidence="11" type="ORF">Mal33_01460</name>
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    <organism evidence="11 12">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
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            <taxon>Planctomycetia</taxon>
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mal33</strain>
        </source>
    </reference>
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        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the kinesin light chain family.</text>
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    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="C:kinesin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024983">
        <property type="entry name" value="CHAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002151">
        <property type="entry name" value="Kinesin_light"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12770">
        <property type="entry name" value="CHAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00381">
        <property type="entry name" value="KINESINLIGHT"/>
    </dbReference>
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        <property type="match status" value="16"/>
    </dbReference>
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        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
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    <keyword evidence="4" id="KW-0493">Microtubule</keyword>
    <keyword evidence="7" id="KW-0505">Motor protein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
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            <end position="605"/>
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        <location>
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    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00009622"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
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        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF12770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QDV54197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1350" mass="150921" checksum="319F90E047877789" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMB5</accession>
    <name>A0A518IMB5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Major Facilitator Superfamily protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="3" type="ORF">Mal33_01770</name>
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    <organism evidence="3 4">
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="126"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="157"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="192"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="224"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="281"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="314"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="343"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="370"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="403"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="429"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="464" mass="50297" checksum="727E0DB4A3DD39A6" modified="2019-10-16" version="1">MPPPRCDLPRRCISVLTAQESVISELIESSPASNDDADVPDRESPVEDRVPAAASKNFIVLMLYQVVLRVGWIFKTESVIMPAVLDFLGGSGMLRGLLPPINRVCQSLPALLMAGQMQMAPRKKSWLCVCTVLMAICFALLAVGFCLLDSHPVTLQVFFIAIYAIFFVATGMTQVLFHTLQGKLIPVGDRGRLLLVTNVVGVTAAVGAVWICMPAWVTAEGVEFHWLFATSSIAFFVAAAIAWCVDEPAVISEAPEAVQGIRARYAEAVLPFRDDPNFRRLAIAAALFGSTIMLFPHYQSLGRGGLLGGDFRSLMLWLIVQNLGTAAFSMVVGPLADRRGNRIALRLGLIGVTAAPLLAIGLVWTEIAWAFPIVFVLVGLTPVLLRLFMNYTLEVAPTDKHPSYLAAISVATGLPVLCSPVVGMMIDRVGFSPVFVAISLCGVAAWWISGRLEEPRCSQSNRKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMC3</accession>
    <name>A0A518IMC3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Thioredoxin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">trxA_1</name>
        <name evidence="2" type="ORF">Mal33_01870</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Planctomycetia</taxon>
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    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="1">
        <location>
            <begin position="13"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="422" mass="44950" checksum="AC820C9990D276FD" modified="2019-10-16" version="1">MHMLCYLLLAAGVSGSSDSVLVEFTQPGCHACVTMEPVVGQLQREGVAIRRVDAARESHLVQRYRVTSFPTYLVLSGGREIARLQGTQPIQTLRQALANRQGQRIRDTGARNVKPEVPQTPLSAVAASPVSQAIPGEAMPSVDLAQAVERAQAATVRIRVREQGAVGVATGTIIDTHGEEALVLTCGHVFRDSQGKAPIEVELFIQGQIHTVPGQLIDYEAKTRDIALVSIKPGFPVQPVPVISKDQLPTSGTAAFSFGCDRGADPTRRDTRITAVNKYNQHLGASNLEIAGAPTIGRSGGGLFDHQGRIVGVCNAADFEDDIGIYAGPGTIQWQLDRVNLASLYQPRAAVAAATPRSNVPAPPTRLAAVTSPAASAPAAQIASNQEVIVILRDKNRPDNPTKIKTFDQPTPDMLKLLGLTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMG9</accession>
    <name>A0A518IMG9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Planctomycete cytochrome C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_02400</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011429">
        <property type="entry name" value="Cyt_c_Planctomycete-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011444">
        <property type="entry name" value="DUF1549"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022655">
        <property type="entry name" value="DUF1553"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07635">
        <property type="entry name" value="PSCyt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07583">
        <property type="entry name" value="PSCyt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07587">
        <property type="entry name" value="PSD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022036801" evidence="1">
        <location>
            <begin position="22"/>
            <end position="1184"/>
        </location>
    </feature>
    <feature type="domain" description="PSCyt1" evidence="4">
        <location>
            <begin position="40"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="domain" description="PSCyt2" evidence="2">
        <location>
            <begin position="151"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="domain" description="PSD1" evidence="3">
        <location>
            <begin position="871"/>
            <end position="1127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV54290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1184" mass="131407" checksum="68068F67AA30156C" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMN9</accession>
    <name>A0A518IMN9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">UPF0056 membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Mal33_03140</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the UPF0056 (MarC) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002771">
        <property type="entry name" value="Multi_antbiot-R_MarC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33508">
        <property type="entry name" value="PTHR33508"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01914">
        <property type="entry name" value="MarC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="64"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="106"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="131"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="173"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV54360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="201" mass="20915" checksum="EE349A7E0C10A04F" modified="2019-10-16" version="1">MNDQIQAIVTVLSLMNPAICAAMFTAAETDRPFDEKATNATKAALAILVILSIAALIGTRLLHVFGISLDAFMVAGGGVLAWMGFSMLNRHADAEASKSQQSLTPLILFAASPGTITGVITLSAVHTQLKLPVTALISVAVATVCTWIVMLLAARFSSAQNGGGFLRDTMTRFMGLIVLSMGVQFALTGFHAFAKSGAVAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMP2</accession>
    <name>A0A518IMP2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Glutamate decarboxylase</fullName>
            <ecNumber evidence="3 7">4.1.1.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">gadB</name>
        <name evidence="8" type="ORF">Mal33_03110</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>H(+) + L-glutamate = 4-aminobutanoate + CO2</text>
            <dbReference type="Rhea" id="RHEA:17785"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:59888"/>
            <dbReference type="EC" id="4.1.1.15"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 5 6">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the group II decarboxylase family.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.15" evidence="3 7"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004351">
        <property type="term" value="F:glutamate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006536">
        <property type="term" value="P:glutamate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010107">
        <property type="entry name" value="Glutamate_decarboxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002129">
        <property type="entry name" value="PyrdxlP-dep_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43321">
        <property type="entry name" value="PTHR43321"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00282">
        <property type="entry name" value="Pyridoxal_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01788">
        <property type="entry name" value="Glu-decarb-GAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="4 6 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="5">
        <location>
            <position position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602129-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV54357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="465" mass="52835" checksum="836F6A0212B18BAF" modified="2019-10-16" version="1">MPLHDKDSIRELLDDDVYGSTDLAGQLPKYKFPGEEHDPRHVYSLVHDELMLDGNSRQNLATFCQTWAEPEVHKLMDECMDKNMIDKDEYPQTAEIEARCVHMLADLWNSPAAANTIGCSTTGSSEAAMLGGMAMKRAWEAKRKAAGKPYDKPNLITGPVQVCWHKFARYWDVELREIPMENDRLIMTPEEVIKRCDENTIGVVPTLGVTFTCQYEPVQQVSDALDQLEKETGLDIRMHVDGASGGFLAPFCAPDLVWDFRLPRVKSINTSGHKFGLSPLGVGWVIWREEQDLPQEEIFWVNYLGGNMRDIALNFSRPGGPVVCQYYNFLRLGKEGYRKIHTACYETAKFVARELEKLDYFDVIYDGDMESGIPALCWKIKEGVEPGFSLYDLADRLRSRGWQVPAYALPANRQDLAIQRILVRHGVSRDLGALLIEDIKRSIDYFKKHPVQSQITSEEASGFHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMS0</accession>
    <name>A0A518IMS0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_03440</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021697749" evidence="3">
        <location>
            <begin position="29"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="195"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="144"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="216"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV54390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="230" mass="25817" checksum="D556763D13BF990E" modified="2019-10-16" version="1" precursor="true">MNEVNVLSNWRGAVACIVLMLAATSGFAAEYDLSRDAIAQADGSAAEPPVEGERRVTEFVKSHLPELESVLASLKKHSAKEYQKAIGDLARTSRRLEQLQQRDPDGFELELTFLQWQTRVDIALAQLQVRDNEKTRAQLRKSLASREQARVARARHDKARLTERIARLQTQLQRLTDQLESVDVQKNADKAYAGAIRRLDAKQARPNTASRTRKNAKPKPAADPKTPENK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INB8</accession>
    <name>A0A518INB8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type II secretion system protein G</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">xcpT_1</name>
        <name evidence="2" type="ORF">Mal33_05390</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011453">
        <property type="entry name" value="DUF1559"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07596">
        <property type="entry name" value="SBP_bac_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="335" mass="36525" checksum="EFEBD414D05D14D8" modified="2019-10-16" version="1">MSQHPQRHSRRGFTLVELLVVIAIIGILVGLLLPAVQSAREAARRMQCSNNMKQLGLALHNYHDTYQVFPSGCIDSNRKTNSPTDALNNNNGLGWGTLLLPFIEQSPLYDQISFETGSFGRSWQDKNNDGTTNDPIDSAKVVIDAFVCPSDPMSGLNSDKSDYGKSNYMAIAGRYAVQTDSNGSPLGQRNGMFFENSNRKFRDVIDGTSNTLFLSERTTQNDNVNSTQCGGAPCNWAGGLWIGPRIVSSSAAWHTGLYLFDVANVGGYDTGYSLTHGFGRSSATWGADWNAKGCHPGGMQATLGDGSVRFITETIDFDLYRNLHTPQDGNVISNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INH2</accession>
    <name>A0A518INH2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 12">GTP 3',8-cyclase</fullName>
            <ecNumber evidence="3 12">4.1.99.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Molybdenum cofactor biosynthesis protein A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12 14" type="primary">moaA</name>
        <name evidence="14" type="ORF">Mal33_05940</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>AH2 + GTP + S-adenosyl-L-methionine = (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate + 5'-deoxyadenosine + A + H(+) + L-methionine</text>
            <dbReference type="Rhea" id="RHEA:49576"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:131766"/>
            <dbReference type="EC" id="4.1.99.22"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="12">Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 12">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Monomer and homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the radical SAM superfamily. MoaA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="4.1.99.22" evidence="3 12"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00344"/>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019008">
        <property type="term" value="C:molybdopterin synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061798">
        <property type="term" value="F:GTP 3',8'-cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904047">
        <property type="term" value="F:S-adenosyl-L-methionine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01225_B">
        <property type="entry name" value="MoaA_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
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            <end position="253"/>
        </location>
    </feature>
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            <position position="48"/>
        </location>
        <ligand>
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        </ligand>
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            <position position="55"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
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        <location>
            <position position="59"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
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        </ligand>
    </feature>
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        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
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        <location>
            <position position="62"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
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        </ligand>
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        <location>
            <position position="98"/>
        </location>
        <ligand>
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        <ligand>
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        <ligand>
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        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
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        <location>
            <position position="292"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
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        <location>
            <begin position="294"/>
            <end position="296"/>
        </location>
        <ligand>
            <name>GTP</name>
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        </ligand>
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        <location>
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            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
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        </ligand>
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            <dbReference type="ARBA" id="ARBA00000034"/>
        </source>
    </evidence>
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        </source>
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        </source>
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        </source>
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        </source>
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            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
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        </source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="362" mass="40002" checksum="CD59194DDA0790E1" modified="2019-10-16" version="1">MLSVRLPGSFYLDCKNALTSFADSAPSVPRDAADRLIDRFGRVHRSLRISVIDRCNIRCFYCMPEHVDNFLPRADLLSFDEIVRVVGLLASAGVSKIRVTGGEPLLRPNLDALIARIAAVSGVDEIALTTNGILLPKFAESLKASGLQRLNISLDTLNEANFQRISRRSGVDRVIAGIDHAIDLGFEQIRLNALAIRGLTETEIVPLVDFARRRNLTLRFIEYMPLDADRAWRDGDVLTGDTIRQRLESQYGPLLETGRDDPAQPAIDYRFADGSGRVGFINPVSKPFCDACDRLRLTADGGLRNCLFSDRNWDLRALLRSGAGDADLINLITESVAAKEPGHLISRPGFQQPQRAMYQIGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INK7</accession>
    <name>A0A518INK7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SHD1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_06260</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Planctomycetia</taxon>
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    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
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                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4 5">Mal33</strain>
        </source>
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        </location>
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            <begin position="19"/>
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        </location>
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        <location>
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            <end position="542"/>
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        <source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="555" mass="60514" checksum="255A47B5462FCC60" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INQ3</accession>
    <name>A0A518INQ3_9BACT</name>
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        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
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        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetia</taxon>
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    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DUF502"/>
        <property type="match status" value="1"/>
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    <proteinExistence type="predicted"/>
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    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="24"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="129"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="297"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="317" mass="34997" checksum="080FA7FEB998238E" modified="2019-10-16" version="1">MNPTNSDELSPAASPSTATTFRRAILHGLGIVMPPLLTILLFVWAWTTTENYVLSPLEAGIRNVLVWNLQEIEDVKPVDRNFVADPTGKKFLPQYVVSYVDQNLHRLGPFEPVPGTAIAYWHRYVQLVYLPRTVVVPFFLLMFLILLYFLGRMFANGIGRFFVRAMDRFIGRVPVVSNVYSSVKQVTDFVFSERDIEFNRVVAVEYPRKGIWSIGFVTGQSMADISAAANEPVLSVLMPTSPMPVTGFTVTVRKSEAVDLDLTIDQAIQFIVSCGVVVPAKQQQAFSRLQLNLPGSGNASAMLPGDDGSADSSTSAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INS3</accession>
    <name>A0A518INS3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_06900</name>
    </gene>
    <organism evidence="3 4">
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        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Planctomycetia</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
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                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
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                <person name="Galperin M.Y."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 4">Mal33</strain>
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        <location>
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    </evidence>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
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    </evidence>
    <sequence length="1149" mass="125409" checksum="D78B62A179FA4A0C" modified="2019-10-16" version="1"> </sequence>
</entry>
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            <authorList>
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                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
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                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
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            <strain evidence="2 3">Mal33</strain>
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    </reference>
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    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
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            <begin position="21"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="287" mass="31895" checksum="AE61258F5FA7468E" modified="2019-10-16" version="1" precursor="true">MRARITSIVWLVAVCGAGLAAGPNDDLITPAMEDGSPAAGRRVRQVAAEYAGTNVHHALYLPVDWKPGGRYPVIVEYTGNKFPPSHSTGQVKDANLGYGISGGEGFIWVVMPCVAVGGQENAVTWWGDRQATVDYCKTNLPRVCAKFGGDLENLFVCGFSRGAIAASYIGLADDEIASFWKGMFTHDHFDGERQWNYPDSDRESALQRLARLRGRPVLVSSTRASAIRDNYLIDHLDLAAFTFLDVPTKQLFSIPEGPYLHPHMDLWMHRESRYRQQARQWLQLALQ</sequence>
</entry>
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        <submittedName>
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            <authorList>
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                <person name="Boedeker C."/>
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                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
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                <person name="Jeske O."/>
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                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
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                <person name="Jogler C."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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        <location>
            <begin position="123"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="158" mass="18100" checksum="37D58B9EF87D4806" modified="2019-10-16" version="1">MLSHLKNVALTVVAIGMLSQFAIHDAEARYGGRQYYSSWSYQPARSYHYTRYYYKPVTTATSYSYHYCISYPSQPRYVYYYNPVSRQYWGRYDLEGTEGAQYSLLAEKDRKKNLEDIPESAFPAPAAMPQIPGSKDGVAIEPIKEKPGDEPKDLPVAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP93</accession>
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    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Amann R."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <property type="project" value="InterPro"/>
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    </dbReference>
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        <location>
            <begin position="19"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="72" mass="8010" checksum="44C638D7E7A179C8" modified="2019-10-16" version="1">MKQNLSDGEADLKAPKTVRTSVCIPRPDYEELERFSRKTTSSVAQIVRDAVHAYLLSRDIPHSDADNNGAHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP97</accession>
    <name>A0A518IP97_9BACT</name>
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    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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                <person name="Boedeker C."/>
                <person name="Pinto D."/>
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                <person name="Rast P."/>
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                <person name="Amann R."/>
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                <person name="Devos D.P."/>
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                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8 9">Mal33</strain>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="component" value="Chromosome"/>
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        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002197">
        <property type="entry name" value="HTH_Fis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002078">
        <property type="entry name" value="Sigma_54_int"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025662">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025943">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02954">
        <property type="entry name" value="HTH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00158">
        <property type="entry name" value="Sigma54_activat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01590">
        <property type="entry name" value="HTHFIS"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00675">
        <property type="entry name" value="SIGMA54_INTERACT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00676">
        <property type="entry name" value="SIGMA54_INTERACT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50045">
        <property type="entry name" value="SIGMA54_INTERACT_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Response regulatory" evidence="7">
        <location>
            <begin position="11"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma-54 factor interaction" evidence="6">
        <location>
            <begin position="148"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="5">
        <location>
            <position position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV54892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="481" mass="53247" checksum="1E9999266C0A5272" modified="2019-10-16" version="1">MNRPSRRTSQTLLVIDDEAPILTAFERAFASETTTVLVAENATDGEAVFMETRPDVVVIDLSLPDMSGLECFRRLHKVDPRVPVIFITGHGTVETAIEATQLGAYDFLFKPLELDEMRQLLEKAFNLSRMVRVQPVLADEEDTVADAIVGRCRAMKEVYKAIGRVASQNLTVLLLGESGTGKEVVAQAIYHHSARSDGPFQAINCAAIPDALLESEIFGHEKGAFTDAHRQRIGKLEQADKGTLFLDEVGDMSPMTQAKILRVLQDQTFERVGGNTPIKVDARIIAATNHDLKKLVSEGLFRADLYFRLSVVSIHLPPLRQREDDLRVLAEYFLRKYSNEFGKDIRTLAPETLELLEQYHWPGNVRELESAMKQSLLIARGNVLLPEFVPRLSDGSTPLISGKSEDEYLSKSFVAERLDAGSKNLYAEAIRTAESQLFRQVLQHTAGNQLKASSILGISRVTLRSKLKALGIEAADFAGGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPD7</accession>
    <name>A0A518IPD7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Transcription-repair-coupling factor</fullName>
            <shortName evidence="8">TRCF</shortName>
            <ecNumber evidence="8">3.6.4.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8 11" type="primary">mfd</name>
        <name evidence="11" type="ORF">Mal33_09160</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">In the C-terminal section; belongs to the helicase family. RecG subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">In the N-terminal section; belongs to the UvrB family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.-" evidence="8"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000716">
        <property type="term" value="P:transcription-coupled nucleotide-excision repair, DNA damage recognition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00969">
        <property type="entry name" value="TRCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036101">
        <property type="entry name" value="CarD-like/TRCF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003711">
        <property type="entry name" value="CarD-like/TRCF_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004576">
        <property type="entry name" value="Mfd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037235">
        <property type="entry name" value="TRCF-like_C_D7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005118">
        <property type="entry name" value="TRCF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041471">
        <property type="entry name" value="UvrB_inter"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02559">
        <property type="entry name" value="CarD_CdnL_TRCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03461">
        <property type="entry name" value="TRCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17757">
        <property type="entry name" value="UvrB_inter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01058">
        <property type="entry name" value="CarD_TRCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00982">
        <property type="entry name" value="TRCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141259">
        <property type="entry name" value="SSF141259"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143517">
        <property type="entry name" value="SSF143517"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00580">
        <property type="entry name" value="mfd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7 8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="3 8 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="9">
        <location>
            <begin position="564"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="10">
        <location>
            <begin position="734"/>
            <end position="900"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QDV54950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1095" mass="121983" checksum="9439605530EE0639" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPG7</accession>
    <name>A0A518IPG7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytochrome c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Mal33_09460</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037524">
        <property type="entry name" value="PA14/GLEYA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011658">
        <property type="entry name" value="PA14_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011041">
        <property type="entry name" value="Quinoprot_gluc/sorb_DH"/>
    </dbReference>
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        <property type="entry name" value="Cytochrome_CBB3"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="4"/>
    </dbReference>
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        <property type="entry name" value="SSF50952"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="4"/>
    </dbReference>
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        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021845757" evidence="5">
        <location>
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            <end position="1395"/>
        </location>
    </feature>
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        <location>
            <begin position="35"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="6">
        <location>
            <begin position="179"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="6">
        <location>
            <begin position="285"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="6">
        <location>
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            <end position="566"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="6">
        <location>
            <begin position="584"/>
            <end position="678"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV54978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1395" mass="152911" checksum="BDB0FBD04A64F6B8" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPM2</accession>
    <name>A0A518IPM2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_09900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="DUF420"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DUF420"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="129"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="151" mass="16800" checksum="E7324EC22E931128" modified="2019-10-16" version="1">MEWLASNLPHATASLNSLATVLLVIGLVMVKRGNLKAHRNVMITCFAVSGLFLALYLLHKVALFQTTGSPNRRFPTDVSSAARTVYFTILGTHLLLAITVPPLAIAAIVQGLKDNREKHRKIVRFAFPIWLYVSITGVVVYYMLYWAYPVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPM6</accession>
    <name>A0A518IPM6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_10190</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="405" mass="44666" checksum="4AF0F3B201AEC92C" modified="2019-10-16" version="1">MADPTVLNESGLDAASRDYVAWVADALSLQMQTDSGGGIALLPLAPPADNEPPPAAPISLDTTGDLAKLWDLQRQFAGGATEAQASGEPSHVPGIAAVVLEPYKIRDGRVQLAGCTLEPRPFLRISTLGSEIEHHWFGRDGIKIDTDLLNRLNLDRLDAIPPRLKPGDQSTMTAWIDAAASSLGTTQRIGVTVAWSQWVAGKVRIQFDQGAQTSLAFQGWAIEWEKGLLPPPMFKCPITEIESYDLVCTEDGTITAREGVGRCELTEREVLRTELGQCAVSGKNVLNDMLTTCPISHERFLSELAKKCDWCQRLVSPHAMDKNRCQQCSNATQNEAMQNIVDKLQSAHPEYQKLSNWQGWVSDELALLIGRHWFSETLLLVSCPDLQIQRIGSRRRFSKAWHFDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPQ3</accession>
    <name>A0A518IPQ3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 11">Delta-aminolevulinic acid dehydratase</fullName>
            <ecNumber evidence="4 11">4.2.1.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">hemB</name>
        <name evidence="13" type="ORF">Mal33_10370</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>2 5-aminolevulinate = H(+) + 2 H2O + porphobilinogen</text>
            <dbReference type="Rhea" id="RHEA:24064"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58126"/>
            <dbReference type="ChEBI" id="CHEBI:356416"/>
            <dbReference type="EC" id="4.2.1.24"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 1/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Homooctamer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the ALAD family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.24" evidence="4 11"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00318"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004655">
        <property type="term" value="F:porphobilinogen synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001731">
        <property type="entry name" value="ALAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030656">
        <property type="entry name" value="ALAD_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11458">
        <property type="entry name" value="PTHR11458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00490">
        <property type="entry name" value="ALAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001415">
        <property type="entry name" value="Porphbilin_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00144">
        <property type="entry name" value="DALDHYDRTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01004">
        <property type="entry name" value="ALAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00169">
        <property type="entry name" value="D_ALA_DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="7 11 13" id="KW-0456">Lyase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 11" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Schiff-base intermediate with substrate" evidence="9">
        <location>
            <position position="202"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate" evidence="9">
        <location>
            <position position="257"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="242"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR001415-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR001415-5"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU004161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="QDV55068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="332" mass="36268" checksum="A2F1EDDAD4F2FEB7" modified="2019-10-16" version="1">MSPRGEYPTTRMRRVRRFDWSRRLVRENGLTPNDLIWPVFVVDGENVRQPIASMPGVERLSIDLLVQRAAEAVELGIPAMALFPVTPSEKKTPGAEEAINPENLVCRAVRAVKAKVGDSLGIICDVALDPYSSHGHDGLLKDGYVVNDETIEVLCQQAIVQAQAGCDVIAPSDMMDGRIGAIRKHLDQANLHDTQIMSYAAKYASAFYGPFREAVGSGKNLAGGDKKTYQQDPANTDEALHEVALDLAEGADMVMVKPGMPYLDVVHRVKDTFSVPTFAYQVSGEYAMLSAAIQCGWLAREQVVLESLLAFKRAGADGILTYFAIDAARLMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPW2</accession>
    <name>A0A518IPW2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Bacterial transcription activator, effector binding domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_10810</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010499">
        <property type="entry name" value="AraC_E-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029442">
        <property type="entry name" value="GyrI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019587">
        <property type="entry name" value="Polyketide_cyclase/dehydratase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011256">
        <property type="entry name" value="Reg_factor_effector_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06445">
        <property type="entry name" value="GyrI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10604">
        <property type="entry name" value="Polyketide_cyc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00871">
        <property type="entry name" value="AraC_E_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55136">
        <property type="entry name" value="SSF55136"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AraC_E_bind" evidence="1">
        <location>
            <begin position="157"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="309" mass="35107" checksum="9B89C6F4FF5BDB11" modified="2019-10-16" version="1">MPAYRVERSILIDADAEKVFDTVADFNTWNIWSPWLVIAHEAVVTVTDDPNSVGSIYRWSGEFVGRGEVEHAQLDRPRKIVDTLRFEKPFKSTSQVEFSVQSEAGQTRLSWVMNGSLPWFLFWMRRNMETYIGMDYARGLKMVREYIQTGRVLSKSTVEGIEKIPARRVVGLRESCQLEEIGPVMGKTFARVAEEFSRHNLPLDGEILSVYHPSDMMKGQFEFTCGFVVDSGVALPPGLVECSIPAAKALHVKHVGSYENLGNAWSGAHQFANYRKHKLAKIETLEIYRNTPQDTADEDLVTDIYLPLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQM0</accession>
    <name>A0A518IQM0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_13340</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="140" mass="16354" checksum="8B60AA04DB9A08AF" modified="2019-10-16" version="1">MKVWTPHHPGTFPLTAPNLIVDASRSIYYRNLQYRSAIHELHRRLQGETQFLWCLTSQNTFQRHCESIDLIEWDLDVPNTQILTLYREDAWENIYHGRSSDWDATFTETVAENVGALVRVPIAPSWATPHWIPVKYPTHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQY4</accession>
    <name>A0A518IQY4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_14710</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="257" mass="29434" checksum="3A9F4DA3AF2C8B4A" modified="2019-10-16" version="1">MKRLISLSLYGSDPIYLQGALRNVRLQKVHFPTWTTRIYASQEIPATLIEQLKAEGAEVVAKVRQNNIDGMFWRFLPVGEPDVDAVIVRDTDSRLTARERAAVDQWIDSGKSLHIMRDHPLHRVVMLGGMWGCRGGKIPDINELLGQWNLAQKKGYDQDFLNDRIYPRFSQDCFIHSELYRYQGEQVHPFPVPRDGGEFIGCVYDADRDTLTPEQHAANLASFTDTQLKDLPRAQPRSMLFRSARQWLRVLRGKAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IR92</accession>
    <name>A0A518IR92_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">50S ribosomal protein L25</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">General stress protein CTC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 9" type="primary">rplY</name>
        <name evidence="6" type="synonym">ctc</name>
        <name evidence="9" type="ORF">Mal33_15860</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008097">
        <property type="term" value="F:5S rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00495">
        <property type="entry name" value="Ribosomal_L25_TL5_CTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.120.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.240.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01334">
        <property type="entry name" value="Ribosomal_L25_CTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020056">
        <property type="entry name" value="Rbsml_L25/Gln-tRNA_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029751">
        <property type="entry name" value="Ribosomal_L25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011035">
        <property type="entry name" value="Ribosomal_L25/Gln-tRNA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020057">
        <property type="entry name" value="Ribosomal_L25_b-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037121">
        <property type="entry name" value="Ribosomal_L25_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001021">
        <property type="entry name" value="Ribosomal_L25_long"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01386">
        <property type="entry name" value="Ribosomal_L25p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14693">
        <property type="entry name" value="Ribosomal_TL5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50715">
        <property type="entry name" value="SSF50715"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00731">
        <property type="entry name" value="bL25_bact_ctc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 6" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_TL5_C" evidence="8">
        <location>
            <begin position="96"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="178"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="182"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF14693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV55609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="206" mass="22328" checksum="B660ABE9E3C413B1" modified="2019-10-16" version="1">MSDVLNVEVRENMGTAATRKLRDTGRIPAVVYGHGGENQHLSVPRKEVELLLRHHSKHVQLAGAANDHVLLKDVQWDPLGIEVLHMDLLRVSLSEKVTITVPVKLHGVAIGLNHHGVMNEILHSVEINVPALKIPEFVELNVNDLDVGQSKTAADIELPEGAELTTDPTAVVVQMNAPAGDKATDEDAEAATEPEVIGAKKEDENE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRC3</accession>
    <name>A0A518IRC3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Phenylalanine--tRNA ligase alpha subunit</fullName>
            <ecNumber evidence="13">6.1.1.20</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Phenylalanyl-tRNA synthetase alpha subunit</fullName>
            <shortName evidence="13">PheRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13 16" type="primary">pheS</name>
        <name evidence="16" type="ORF">Mal33_16250</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + H(+) + L-phenylalanyl-tRNA(Phe)</text>
            <dbReference type="Rhea" id="RHEA:19413"/>
            <dbReference type="Rhea" id="RHEA-COMP:9668"/>
            <dbReference type="Rhea" id="RHEA-COMP:9699"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58095"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78531"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="13">Binds 2 magnesium ions per tetramer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 13">Tetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 13">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.20" evidence="13"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004826">
        <property type="term" value="F:phenylalanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006432">
        <property type="term" value="P:phenylalanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00281">
        <property type="entry name" value="Phe_tRNA_synth_alpha1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004529">
        <property type="entry name" value="Phe-tRNA-synth_IIc_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004530">
        <property type="entry name" value="Phe-tRNA-synth_IIc_mito"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004188">
        <property type="entry name" value="Phe-tRNA_ligase_II_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022911">
        <property type="entry name" value="Phe_tRNA_ligase_alpha1_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002319">
        <property type="entry name" value="Phenylalanyl-tRNA_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010978">
        <property type="entry name" value="tRNA-bd_arm"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11538:SF41">
        <property type="entry name" value="PTHR11538:SF41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02912">
        <property type="entry name" value="Phe_tRNA-synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01409">
        <property type="entry name" value="tRNA-synt_2d"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46589">
        <property type="entry name" value="SSF46589"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00468">
        <property type="entry name" value="pheS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12 13" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="9 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 13 16" id="KW-0436">Ligase</keyword>
    <keyword evidence="10 13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11 13" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="15">
        <location>
            <begin position="120"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="82"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="270"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="QDV55647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="343" mass="38270" checksum="316CE50616DAFEC9" modified="2019-10-16" version="1">MALADFIRSLDDLESQAVAAFREATDNDGLEEVRIRFLGAKNGQLKSVQQQMSSVDGPDKKAAGMRLNAAKGNIQASFEQAVEQLSQRAQKSGPAPDPTLPGNPVRLGHVHPVTQTIEHLKEIMGRMGFEVVEGPEVEDPWHNFVALNIPEDHPARDPLDNFYLATAERNGSGKTYAEGDRLLRSQTSTVQIRVMENRQPPIRVISLGRVYRPDEADATHYPMFHQMEGLLIDRGVTMANLKTVLNMFATSYLGEEVKVRFRPSFFPFTEPSVEVDYWWNGSWIEFGGAGMVDPAVLTAVGYDPEEVTGFAFGLGVERLCMRRHAVTDIRDLFSGDIRFLSQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRD0</accession>
    <name>A0A518IRD0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_16200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="119"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="171" mass="18743" checksum="EA08CFD38D2131E1" modified="2019-10-16" version="1">MSDVSTPASFFRCPISGERAIGVLKVGRRRIPVTLVDASIEGYTLRVAKKYARKLRKDRKWILIAQHERTLVWPQWRFTAENGAATIAVCRLQDITPQEGVRRTWQLTGSIPKDSGSSISGMALGGMLLLMIAIVCLPGIGDDLGTAPRIGSFLSDALRGFGISVRQFLNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRY9</accession>
    <name>A0A518IRY9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phytanoyl-CoA dioxygenase (PhyH)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_17920</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008775">
        <property type="entry name" value="Phytyl_CoA_dOase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05721">
        <property type="entry name" value="PhyH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="275" mass="30276" checksum="939AC013F849D017" modified="2019-10-16" version="1">MKNFSIVPSDDELASVPRDLRFYSVNNDAPTVLTGDQIDRFNRDGYVAPLPIFGDAEISGIRSYFDDLLARVTAAGGNSYSISSAHLKYGPVYDILKDPRIVDCVSDLLGENVIGWGSHFFCKMPHDGKSVAWHQDASYWPLSPSKAVTVWLAIDDADEENACMRFIAGSHHVGHLTYRPSDSAEHNVLNQTIDNPEQYGSVVYNPLPAGSASIHSDLLLHGSESNDSDRRRCALTLRYCSADVHAALDWNQKGVQVRGTDPSGHWSNLTRPAES</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRZ1</accession>
    <name>A0A518IRZ1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Choline-sulfatase</fullName>
            <ecNumber evidence="4">3.1.6.6</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">betC_5</name>
        <name evidence="4" type="ORF">Mal33_18310</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="PTM">
        <text evidence="1">The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.</text>
    </comment>
    <dbReference type="EC" id="3.1.6.6" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047753">
        <property type="term" value="F:choline-sulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="51"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="91"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="148"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="184"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase" evidence="3">
        <location>
            <begin position="264"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="modified residue" description="3-oxoalanine (Ser)" evidence="1">
        <location>
            <position position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR600917-52"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV55852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="703" mass="78083" checksum="7F9AC6F14E85A8EA" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISB8</accession>
    <name>A0A518ISB8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Futalosine hydrolase</fullName>
            <ecNumber evidence="3">3.2.2.26</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">mqnB</name>
        <name evidence="3" type="ORF">Mal33_19750</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.2.2.26" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016799">
        <property type="term" value="F:hydrolase activity, hydrolyzing N-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009234">
        <property type="term" value="P:menaquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009116">
        <property type="term" value="P:nucleoside metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019963">
        <property type="entry name" value="FL_hydrolase_MqnB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000845">
        <property type="entry name" value="Nucleoside_phosphorylase_d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035994">
        <property type="entry name" value="Nucleoside_phosphorylase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01048">
        <property type="entry name" value="PNP_UDP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53167">
        <property type="entry name" value="SSF53167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03664">
        <property type="entry name" value="fut_nucase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNP_UDP_1" evidence="2">
        <location>
            <begin position="35"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="237" mass="24515" checksum="14FFA36B0E258BDB" modified="2019-10-16" version="1">MIDPVPDTSEGDHSANFSPSRERLVLVPTPGELVRVRGSLVAATSVRLELCGFGPIAAAARTASLIALHRPVRVFLVGIAGAVGDRLAVGQASEFDSVSCHGIGAGGGADFQSASELGWNQWSPESGDAIGDRLALTTAAAAETARDLVTVCSASASEADVQAYLQRFPEAVAEDMEGFAVAMACRMHGVPLTIVRGISNIAGDRDKSRWRIAAALDAASKLLQHVLDRPANGANSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISC8</accession>
    <name>A0A518ISC8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_19420</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="40" mass="4583" checksum="ACF77A0758965945" modified="2019-10-16" version="1">MMFPIWFLKLIVFGGLLLCAAGAVLLIVFLICDSRKNRIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISD2</accession>
    <name>A0A518ISD2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_19730</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="104" mass="11836" checksum="2D67222D23E66949" modified="2019-10-16" version="1">MTWASKKKTSHTTTSAAKGQRRTADQQTGFPAGDAGRNQSFMTGPRIEFEVLFFYGWTERELSRVTSRERLGSGTCERIYRFGDSVVRMQFACSGFGQRERPRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISN2</accession>
    <name>A0A518ISN2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Macrolide transporter subunit MacA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_20740</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HlyD_D23" evidence="3">
        <location>
            <begin position="200"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="124"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="237"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="124"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV56095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="425" mass="45945" checksum="4906218101211030" modified="2019-10-16" version="1">MASLIQRLFARYDAISVTHWSQTSDGQLKGLSLRGDNSPEIRQKAAALALQAMTTAETQSRIVSSSQQQFLVAAVLPAVDGEAISILFGCENRGNAAQWFEARTREVELAAAHLAIIHRLESVPPSQTSDSTATDPTPRDNASAPSHALVERLRTWAAKQKQDARWILAIGFAALLIGAIPWQHSIQCAVTCEPALRRFVVAPFDGKLQQSLVGPGDSVDAGQVLAILDGGDLLAQIASLQAKIDQALQRRAAALSSGDGSKSQLERLEVQHLRSEIQMLKSREQNLEIRSPIAGVVVSGDLERAEGIPLQVGENLFEIAPLDRLVAEIAIPESDIANVQIGMPTSIRLDAVAGAYHQAHLTQIHPRSEIRDEASVFIAEAAIDNQDLALRPGMHGTASIQAGRRSVAWLLFHRPYDALRGLIGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISS3</accession>
    <name>A0A518ISS3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CHAT domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_20820</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021802576" evidence="1">
        <location>
            <begin position="27"/>
            <end position="985"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="985" mass="105041" checksum="32A1829C1F81899B" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISV5</accession>
    <name>A0A518ISV5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peroxiredoxin bcp</fullName>
            <ecNumber evidence="2">1.11.1.15</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">bcp_3</name>
        <name evidence="2" type="ORF">Mal33_21440</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.11.1.15" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="1">
        <location>
            <begin position="43"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="216" mass="23972" checksum="0717C40A665CA3E5" modified="2019-10-16" version="1">MTTLREQTEAKMANTRQNNPKFAKRVDALLSSAEVFQSGANALEVGQQAPEFGLPNPQGDSVSLSSWLAKGPVVVTFYRGNWCPYCNLQLRAMQQRLPDLRRLGAELVAITPQLPDESLTQIEQASLEFPVLSDRDARVAAEYGVAWKVPELILDHMRNDRNLELATINGGNGSVLPIPATFVLNREGIVTWRFVDVDYRQRAEPDEIVAALQALV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISY9</accession>
    <name>A0A518ISY9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Demethylspheroidene O-methyltransferase</fullName>
            <ecNumber evidence="5">2.1.1.210</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">crtF</name>
        <name evidence="5" type="ORF">Mal33_21880</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.210" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043803">
        <property type="term" value="F:hydroxyneurosporene-O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008171">
        <property type="term" value="F:O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031725">
        <property type="entry name" value="ASMT_dimerisation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016461">
        <property type="entry name" value="COMT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001077">
        <property type="entry name" value="O_MeTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16864">
        <property type="entry name" value="Dimerisation2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00891">
        <property type="entry name" value="Methyltransf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51683">
        <property type="entry name" value="SAM_OMT_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Dimerisation2" evidence="4">
        <location>
            <begin position="16"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="Methyltransf_2" evidence="3">
        <location>
            <begin position="154"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="259"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="212"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV56207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="352" mass="37457" checksum="84DAC2387AD91028" modified="2019-10-16" version="1">MTHNALRFPETDPTPIFEHFRGNQGSDLLTAAVAHFDLFGSLDRQPCSFDELAQRLGLAARPANVLVTALHAMKLLELREGRLELTPLAREHLVPGSDFDCGDYLGLAAQTPSVLQMVSLLKSNRPIGADASDGGGAAFIYRDGIASAMEAADTARHFTLALSGRAKNVAPALAEVADLTGAQQLLDIGGGTGIYSYALLQKHPALQAILLDRPEVLRVAEEVGQRYGVLDRCKFVGGDMFADPLPADVDAILLSNILHDWDLPECQNLIGRCAAALAPGGRLMIHDVFLNDALDGPLPIALYSASLFSLTEGRAYSGGEYRGWMEAAGLKCSETIATTGVHCGLLIATKPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISZ1</accession>
    <name>A0A518ISZ1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_21870</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022058513" evidence="2">
        <location>
            <begin position="25"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="156"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="190"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="231"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="301" mass="32714" checksum="16552811D8BC5784" modified="2019-10-16" version="1" precursor="true">MRATLTYASIACLAIHGLAIELHANERPSQNPLVKAWHAVGRTYGVGHGPGYHACPNCNGACNCGRSGGTMHYGTAGHHGTPTTYSYDGTTQSLPAYQGNHGQQTEQMLAAPEPNYVSPAEIGIPSEYNQPQAKPERKFAPKKDVQLYVPETVETPPLEIEELPEVEELRPAESPLFSAPKRDSEDSLPIPKLPSQQRNEPQSPSDIPREVQPPKAKTPQVPAFQPRSSTEPPAATPPPQQTAPTPQPPAKKAPFPGNEDDLLVPPDTHLLDSARMQRQTTGQPTYRSANRSRAVIFEPVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IT09</accession>
    <name>A0A518IT09_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_22140</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="81" mass="9326" checksum="46D2DF0E632F2BA3" modified="2019-10-16" version="1">MADQTEAIRKNLVAELNSEDNTKAELEAKHGKVWTTSEMQDEFDALGFMAPFIIVRKRDTGERGSLLFTHSPRFYFSFQPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IT65</accession>
    <name>A0A518IT65_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_22590</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="45" mass="5052" checksum="6E0DDE7189895F3A" modified="2019-10-16" version="1">MAAERKSLEQVLETSTQYEKASSLYDHESLKISAQPPFCVFSCTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITH7</accession>
    <name>A0A518ITH7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Arylsulfatase</fullName>
            <ecNumber evidence="6">3.1.6.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">atsA_18</name>
        <name evidence="6" type="ORF">Mal33_23690</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="PTM">
        <text evidence="3">The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the sulfatase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.6.1" evidence="6"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004065">
        <property type="term" value="F:arylsulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024607">
        <property type="entry name" value="Sulfatase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00523">
        <property type="entry name" value="SULFATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021868597" evidence="4">
        <location>
            <begin position="23"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase" evidence="5">
        <location>
            <begin position="32"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="modified residue" description="3-oxoalanine (Cys)" evidence="3">
        <location>
            <position position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR600917-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV56380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="520" mass="56933" checksum="3192254FAE1C4BB3" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITI0</accession>
    <name>A0A518ITI0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_23820</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="120" mass="12907" checksum="2C423542A9DE023A" modified="2019-10-16" version="1">MSVQQADMFGEFDRAAMVPMKPRKPQKRPHATKVTSRIAYRDGRPRAGTKAAIALECIVAAGRDGRTRREICAATGINYCSIAAPVLALLKADLIVELAATRPTPTGSPAHVLVAREVLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITW1</accession>
    <name>A0A518ITW1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_25170</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="93" mass="10188" checksum="B0A3DC2F7411F2B9" modified="2019-10-16" version="1">MVTYGVRLGDALIARYPDLDLQRPCDDCLQLRVALNAVRPADDSGLPEISRRIVRNANRHALQQFGQSRAEQQVAIAALLSATLNGVPSFPCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITY6</accession>
    <name>A0A518ITY6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">barA_4</name>
        <name evidence="17" type="ORF">Mal33_25430</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009736">
        <property type="term" value="P:cytokinin-activated signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902531">
        <property type="term" value="P:regulation of intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006189">
        <property type="entry name" value="CHASE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042240">
        <property type="entry name" value="CHASE_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03924">
        <property type="entry name" value="CHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM01079">
        <property type="entry name" value="CHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50839">
        <property type="entry name" value="CHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0932">Cytokinin signaling pathway</keyword>
    <keyword evidence="17" id="KW-0418">Kinase</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 10" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="17" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="49"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="367"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="domain" description="CHASE" evidence="16">
        <location>
            <begin position="116"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="14">
        <location>
            <begin position="428"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="15">
        <location>
            <begin position="504"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="14">
        <location>
            <begin position="554"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="15">
        <location>
            <begin position="629"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="14">
        <location>
            <begin position="851"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="15">
        <location>
            <begin position="923"/>
            <end position="977"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="12">
        <location>
            <begin position="995"/>
            <end position="1216"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="13">
        <location>
            <begin position="1236"/>
            <end position="1354"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="10">
        <location>
            <position position="1290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="QDV56551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1376" mass="153239" checksum="B203FFB55AE460AA" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IU65</accession>
    <name>A0A518IU65_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_26230</name>
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    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001434">
        <property type="entry name" value="DUF11"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01451">
        <property type="entry name" value="B_ant_repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021970669" evidence="2">
        <location>
            <begin position="28"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="475" mass="49865" checksum="8F4AE0744C0C7CBF" modified="2019-10-16" version="1" precursor="true">MPSLAFLRIQASSLYALGLLGLSIATSGCQSLAPAPSQPMAQRASQPAQPHPAQQFASAPTAAPAMPPAPQATAAGQPAAAPNGNAVAGVALVTHQQLVATPGGQTEVTAPTYTPDNYPGVYETAGFRNRLSSGLAGGACTACNGGCATCVPDNTGCACCGTAQCPTPMICQFPGDPNEYLCDGGDRMPSARVLLSNDVGGLGLEDTIVHYETQDGLTYVEPSNRVCVYAPRFAAVRKVTSAVTGENVLATQRVDLPRGPIGIDLRQPSSAVMQPLGPERNVRTMGPDALRDRNRGVPAENVVQPLLAEDVIAVLAGLSIIEQGVLRDADKPWLAKAGQAAIAWSSEEGAQVVIDEVVVGIATNDQKPEELKIFEVGKGRVRLIKLADKQNALPGEFVHFVLRFDNVGDQPVSNVAILDNLTTRLEYVEGSQTCTKGANFSAQDNEGQSLRLRWELTETLGVGEGCVIRFKCKVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IU94</accession>
    <name>A0A518IU94_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_26460</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021833698" evidence="1">
        <location>
            <begin position="24"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="455" mass="48836" checksum="7142B46187D84453" modified="2019-10-16" version="1" precursor="true">MKRIPSPAWLMLLSLFLSGPVSADEPSLRVGRFSVDASPPVGSPLAYDPTIGVQTPLSCSGIVLLGSGEPIVLCAIDWIGVGNDGNREFRRALAKAAGTTPDRVAVHSLHQHDAPACDFTAAQLLAQHGVTKVRYDSHFAQQVIERAAKAVAEATADTTSVTHLGVGEGEIEKVASNRRVLGEDGKVKYVRYSATRNPVIRDAPVGTIDPMLKMISFWNGESAVAVLTYYATHPQSYYRTGLANPDFPGMARNARQAETGVPHIHFNGAGGNIGAGKWNDGSKENRQVLADRVAAGMKKAWEATKRTPIAAADIGWETESVQLPVGKHLQAEPLQKILEDTSAAGPARQAAARNLVWLRRCEAGDWPIEIACLRIGKARVLHMPGELFVEYQLAAQKQRPDLFVAMAAYGDYAPGYIGTEIAYGQGGYETSERASRVAPQVEGVLTGAVNRLLAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUC7</accession>
    <name>A0A518IUC7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_26760</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="316"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="73"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV56678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="335" mass="37233" checksum="83801E8F028440EE" modified="2019-10-16" version="1">MSRRKRSDQLSGGHDSFLDIVANLVGILIILVVILGARSHQLAQEIEIEPPTEAELALIDREHRTALSVSRDVERLEKSISAYDGELEHRRKEREVLMQLLDVAQQQWEESLAEMDEQKQKTAALQRDREIAENELAELNAQASALEEVPESIVAVEHLPTPMAKTVFGDEVHFRLKDGLLAMVPVDALLDEIKEDFQRLASSARSGDKESSVGPIRDFVAHYSMQMSRESVARGGQIGMASRVQVAELIIEPLREPIGEPIAQALQPQSQLAYELAGRDPASTTVTVWVYPESFAQFRQVKEYLYRMGFATAGRPLPHGHPIAGSPSGSRSQSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUP4</accession>
    <name>A0A518IUP4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_28110</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021998834" evidence="1">
        <location>
            <begin position="20"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="136" mass="14030" checksum="4BB380CA182A597B" modified="2019-10-16" version="1" precursor="true">MKNVSQLFIVALLVAPVLIGCGSTDPVQVTDAQNLNAQVEGLGDAAGDEASFAKAFVAGAAPENRKDYGARGFQVVGDATVDGDSATVPVKIFGGVYSTTGKDGGSKKPSDATETEQVWTLQRNGDTWKIKDAPLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUT3</accession>
    <name>A0A518IUT3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">sn-glycerol-3-phosphate import ATP-binding protein UgpC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ugpC</name>
        <name evidence="6" type="ORF">Mal33_28310</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008995">
        <property type="entry name" value="Mo/tungstate-bd_C_term_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013611">
        <property type="entry name" value="Transp-assoc_OB_typ2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08402">
        <property type="entry name" value="TOBE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50331">
        <property type="entry name" value="SSF50331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="4"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="36"/>
            <end position="43"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV56830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="335" mass="36557" checksum="9658FD5E6F218FC4" modified="2019-10-16" version="1">MAGLAIRKLCKSFAGRIVLDHLELSVDPGQLVVLLGASGSGKTTLLRLIAGLETPDAGEIAIGGREVGRLSPRQRNVSMVFQDFALYPHMSVGDNIAFPLRGRKFSRAQVASKVADVAEKLGLEALLDRRPDQISGGQQQRLAVARALVRDSQLLLMDEPLSNVDVRRRDAMRYELRSLQKEFALTVLYVTHDQTEAMLLGDQIAVIDRGVIQQMAPPDVIYDQPANRFVAQFIGSPPMNFIPDGRAGLLGIRPEDLSFRSAGEDDLKIDGVVDAVQCLGSHNVVHLRTDEGPVAVIVDRQQRVELGEQLTACAARCRLHRFATSDGARLASPLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUT7</accession>
    <name>A0A518IUT7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Pantothenate synthetase</fullName>
            <shortName evidence="5">PS</shortName>
            <ecNumber evidence="5">6.3.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Pantoate--beta-alanine ligase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Pantoate-activating enzyme</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 6" type="primary">panC</name>
        <name evidence="6" type="ORF">Mal33_28480</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>(R)-pantoate + ATP + beta-alanine = (R)-pantothenate + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10912"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15980"/>
            <dbReference type="ChEBI" id="CHEBI:29032"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57966"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.2.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 5">Cofactor biosynthesis; (R)-pantothenate biosynthesis; (R)-pantothenate from (R)-pantoate and beta-alanine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="5">The reaction proceeds by a bi uni uni bi ping pong mechanism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 5">Belongs to the pantothenate synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.1" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00028">
        <property type="reaction ID" value="UER00005"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004592">
        <property type="term" value="F:pantoate-beta-alanine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015940">
        <property type="term" value="P:pantothenate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00560">
        <property type="entry name" value="PanC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00158">
        <property type="entry name" value="PanC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003721">
        <property type="entry name" value="Pantoate_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042176">
        <property type="entry name" value="Pantoate_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21299:SF1">
        <property type="entry name" value="PTHR21299:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02569">
        <property type="entry name" value="Pantoate_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00018">
        <property type="entry name" value="panC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 5" id="KW-0566">Pantothenate biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="37"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="30"/>
            <end position="37"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="61"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="147"/>
            <end position="150"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="153"/>
        </location>
        <ligand>
            <name>(R)-pantoate</name>
            <dbReference type="ChEBI" id="CHEBI:15980"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="184"/>
            <end position="187"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV56847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="283" mass="30625" checksum="238008E3940A3B1A" modified="2019-10-16" version="1">MKIVKLVSEAQRWTFDQRAIGNRVGLVPTMGALHAGHISLAQRSRTTCDRTAATIFVNPTQFAPSEDLDKYPRTLDADLEKLEAAGVDLVFTPEPSEIYPAGFSTYVSPPAVGGTLEGASRPDHFRGVTTVVMKLFNIVPATHAFFGQKDYQQAAVISAMCRDLNVPIQLEICPIVREPDGLAMSSRNRYLTDDQRQRALGLSRALQAAEQQFHSGATDGPQLEQTMLDALAEAKVDTIEYAVIADAITLGPLPTIDRPAVALIAARVGATRLIDNTLLTPGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IV20</accession>
    <name>A0A518IV20_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glucans biosynthesis glucosyltransferase H</fullName>
            <ecNumber evidence="3">2.4.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">mdoH</name>
        <name evidence="3" type="ORF">Mal33_29210</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.4.1.-" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="378"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="416"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="451"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="513"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="535"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_2-like" evidence="2">
        <location>
            <begin position="106"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="675" mass="74519" checksum="6327C79437890B73" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVI3</accession>
    <name>A0A518IVI3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_31010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010869">
        <property type="entry name" value="DUF1501"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07394">
        <property type="entry name" value="DUF1501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="450" mass="50476" checksum="951AD1C90619EF01" modified="2019-10-16" version="1">MLNRRAMLRVGGAGMLGMSMPKLIRAAEQTRQIKPKAKSVIFLFQWGGPSQLDTFDMKPNAPAAVRSPYRPIASSADGIEVCELLPNMAKQMHHVSLIRTMTHKMKNHASAGYYALSGHEPPSDDQRLRDSLDLFPAYGSVVDHLLPSDSSMPSFVSYPHVIRDGSIVPGQHASFLGKGHDPLLFLEDPNDKNFQLPELSLPDGLSIDRLHRRREMQQLVDRQMRLMEHSGEARGFDQYYERAISMLTSDNVRKAFDLSAEPTTVREAYGRTSYGQSCLLARRLVESGVKFVTVYFSNSIGGRRVGQGGWDTHGFDNTRMYKIVDKYQMPLTDQTLPTLIDDLHQRGLLEETLVVWMGEFGRTPEINKNVSRDHWPQCYTALLAGGGVKGGYVHGKSDERAKFPLEKAVKPEDLAATMYQLLGIDPNTEIYDRDNRPLIIGGRPLYDVIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVI6</accession>
    <name>A0A518IVI6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_30960</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="69" mass="7584" checksum="0DB72D0EBF07120A" modified="2019-10-16" version="1">MRSVLWEFIADGSRENRTLTACRFNHNELLCISRLGVSPGLAASEPGLTPKRLIKPTRGIASVAAWFSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVS7</accession>
    <name>A0A518IVS7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">EVE domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_31980</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002740">
        <property type="entry name" value="EVE_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01878">
        <property type="entry name" value="EVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="SSF88697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EVE" evidence="1">
        <location>
            <begin position="2"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="159" mass="18364" checksum="C0EB571033AC2EAE" modified="2019-10-16" version="1">MKYWLMKTEPGTYSIEDLAKEKRKTTCWEGVRNYQARNMMRDDFKKGDRVLFYHSGGKDPAVVGTAKIAKGAYPDHFAWDSGSKYYDPKSSPENPRWFMVDVQLDKAFEQPVTLSQMRNEPQLEQMELLRKGSRLSVQPVTESEFEVVLKMAEAAKNKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVV7</accession>
    <name>A0A518IVV7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_32240</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="49" mass="5344" checksum="B5C45000164A974F" modified="2019-10-16" version="1">MREKHYSAPVILPVLETTKPRQSMFADGVKSPAGRGGWGWGCSDCADLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVW9</accession>
    <name>A0A518IVW9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Putative pterin-4-alpha-carbinolamine dehydratase</fullName>
            <shortName evidence="4">PHS</shortName>
            <ecNumber evidence="4">4.2.1.96</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">4-alpha-hydroxy-tetrahydropterin dehydratase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Pterin carbinolamine dehydratase</fullName>
            <shortName evidence="4">PCD</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_32370</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>(4aS,6R)-4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterin = (6R)-L-erythro-6,7-dihydrobiopterin + H2O</text>
            <dbReference type="Rhea" id="RHEA:11920"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15642"/>
            <dbReference type="ChEBI" id="CHEBI:43120"/>
            <dbReference type="EC" id="4.2.1.96"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the pterin-4-alpha-carbinolamine dehydratase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.96" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008124">
        <property type="term" value="F:4-alpha-hydroxytetrahydrobiopterin dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006729">
        <property type="term" value="P:tetrahydrobiopterin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00434">
        <property type="entry name" value="Pterin_4_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036428">
        <property type="entry name" value="PCD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001533">
        <property type="entry name" value="Pterin_deHydtase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12599">
        <property type="entry name" value="PTHR12599"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01329">
        <property type="entry name" value="Pterin_4a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55248">
        <property type="entry name" value="SSF55248"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 5" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV57233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="116" mass="13010" checksum="2FAC009DD8D95AA8" modified="2019-10-16" version="1">MDISSMDQLAKKKCKPCEGGVDPCSAAEAQQQLQNLPGWQLSDDEKWIRKQWNVKHFVEGMEFLNRVSEVAEQDGHHPDVHLIGYRKVNIELSTHAIGGLSENDFILAAKIDQVAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWE7</accession>
    <name>A0A518IWE7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">spk1</name>
        <name evidence="8" type="ORF">Mal33_34280</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="72"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV57418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="496" mass="55212" checksum="9F43C8B00A5B8FF8" modified="2019-10-16" version="1">MIEFTPEQLASRIIDLGLAPMAEVEAARSEVGTGESTIQDFINILHGKGLLTNLQLDKLRRGERSGYFYGKYKVMYLIGAGTFARVYRAAHRETNQVVALKVLRKRYRDEVAQMEQFLREGRMGLRLRHPNIVSIYEVDPNVKNPFMVMEFVEGETLRDLVRIRGKLQPEVAMKLLVDIASGLSYAASLGISHRDLKLSNVLVSSEGRAKLVDFGLAALADRENPEKVADCPNARAIDYAALERGTNVRKDDPRSDVFFAGAMLYTMLCGEPPLTETRERMKRLNVGRFQDIKPIGQIDPTLPVPAIQVVAKALEFDPEKRLQSAAALQLEGKQALERMKQIREGGPAVAAKVASGEMPTNEGEGRFVMLVESKASLQDVVRDRLKKRGYRVLVISDPVRALGRFVPGDDPPADCVIFSASELGSLALEAFNRFASDEHTADIPAVLLADKSQQNLIRQAKMAPHRVLLSMPLKVLELRTALRKLLAGRPKREEFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWF8</accession>
    <name>A0A518IWF8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_34260</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="904" mass="99956" checksum="AD6D8F141721FA58" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWI0</accession>
    <name>A0A518IWI0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative lysine decarboxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_34590</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009691">
        <property type="term" value="P:cytokinin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005269">
        <property type="entry name" value="LOG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031100">
        <property type="entry name" value="LOG_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03641">
        <property type="entry name" value="Lysine_decarbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00730">
        <property type="entry name" value="TIGR00730"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="333" mass="37688" checksum="BF897E86E1D4258B" modified="2019-10-16" version="1">MTEKPDDSGSNKETRLRSPDLIEVMRKTIDRLVRDRTARGDLKILSRTLIELRYAFSVFRPYRRHRKVTVFGSARTAPSHPTFKAAEEFGRRMAAEDWMVVTGAGSGIMEAGHRGAGREHSMGLNIMLPFEQGANPVIEGDRKLVTMKYFFTRKLMFVKECHAVVSLPGGFGTLDETAEVMTLLQTGKHPMIPVVLLDAPGGTYWKEFGKFVDSQLLDGGMISPEDLRLYKITESVDEAVAELDRFYRVYHSMRYVNGKLVLRLQRPLGAAKLAAVNDRFSDIVVKGGFEQMAALPEEHSEAEIAELPRLVFLFNRRAMGRLRMLIDFINEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWK5</accession>
    <name>A0A518IWK5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Fumarate reductase iron-sulfur subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">frdB</name>
        <name evidence="8" type="ORF">Mal33_34550</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051538">
        <property type="term" value="F:3 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004489">
        <property type="entry name" value="Succ_DH/fum_Rdtase_Fe-S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025192">
        <property type="entry name" value="Succ_DH/fum_Rdtase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13085">
        <property type="entry name" value="Fer2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00384">
        <property type="entry name" value="dhsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0003">3Fe-4S</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="7">
        <location>
            <begin position="154"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV57445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="281" mass="31364" checksum="3382EA7E089FB99C" modified="2019-10-16" version="1">MIAPEKSMPDTIDVRILRQEGPGKKPYWERHRIQYEREMNVISVLQKVAAQAKTVEGKDVAPVAWDCGCLEEVCGSCTMVINGRVRQSCSALVDKLLADQPSHIELAPMTKFPVLRDLLVDRSRLFRGLKKIKAWVPVDGYYDMGPGERQSREQQEQAYPLSQCMSCGCCLDACPQYKKIEVDRITGESEEDYQARCNAEYDNAFIGANAISQVMLFNDHPVGKMMADERMEALTEPGGIQVCGNAQNCVAVCPKEIPLTTSIARAGRAATVHAIKQFFDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWM5</accession>
    <name>A0A518IWM5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATP-dependent zinc metalloprotease FtsH</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ftsH_3</name>
        <name evidence="2" type="ORF">Mal33_34930</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000642">
        <property type="entry name" value="Peptidase_M41"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037219">
        <property type="entry name" value="Peptidase_M41-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01434">
        <property type="entry name" value="Peptidase_M41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140990">
        <property type="entry name" value="SSF140990"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M41" evidence="1">
        <location>
            <begin position="18"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="173" mass="19117" checksum="63A87CE6E5766B6F" modified="2019-10-16" version="1">MNEPPADPAARQAAIELTATAYHEAGHAVMAISLGRPIQKVTIAPGPLQTGGYRLGVCELRKGRGRASQDVIEDEVLILLAGMVAEARFTGRYCPRGAAQDLRTVERVLEGRAKTQRQFERLQRRLLDKTEHLLSDEAHAVAIERIAKELIEKTTISGRAVRHLFEQAKQQFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWP8</accession>
    <name>A0A518IWP8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_35240</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021931282" evidence="1">
        <location>
            <begin position="25"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="245" mass="26407" checksum="ECECE8215FAE7D98" modified="2019-10-16" version="1" precursor="true">MRLLFLFSTVAICSAIGGLGNVDAADGQNSRYFNGNSSGFNSGGAFIMPELLLLRPYNTDPDGDSDSDTHDFKEALRLTIGYVSPTGFGFRGRWLDYDVDTPDADFTVQTVDGELFSTIEMGSRWLGTFSGGARWAEMTETEGDTLEDGYGLIVGAELQYMWSDSIALYSIARHSVLFGDSGNDDDLAVSATELQVGIQGQLALNCGGMVFGRAGVEAQNWNGYTTDDGETFGLFGTVFAVGYQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWR9</accession>
    <name>A0A518IWR9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_35250</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021948582" evidence="1">
        <location>
            <begin position="20"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="214" mass="23424" checksum="C20723D9D575D28A" modified="2019-10-16" version="1" precursor="true">MIVSQRLLWIALVCLTCIAAGCRLPAAKTVASSESEVAPTATTRITYSTASDRLNLARGAATTLLAAHGHAPQMVLPNMTRSTMQIQYPHPAGTAESAQVTLITHLYDDETASVPTMLARFASQHPDSPRSDRRVVEVVTLDIPAWQAVALRNQLQQQNFFRRSRVLNAEVELAVDEPSGRFGKSFHSVPEFDALLLRAAMEGRQLRPNPTPQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IX34</accession>
    <name>A0A518IX34_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Elongation factor G</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">fusA_2</name>
        <name evidence="5" type="ORF">Mal33_36650</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16262">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03713">
        <property type="entry name" value="EFG_mtEFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041095">
        <property type="entry name" value="EFG_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009022">
        <property type="entry name" value="EFG_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035649">
        <property type="entry name" value="EFG_V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004540">
        <property type="entry name" value="Transl_elong_EFG/EF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005517">
        <property type="entry name" value="Transl_elong_EFG/EF2_IV"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14492">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03764">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00889">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="SSF54980"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00484">
        <property type="entry name" value="EF-G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="4">
        <location>
            <begin position="5"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV57652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="696" mass="76724" checksum="8D65BEE25D70A7F4" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IX49</accession>
    <name>A0A518IX49_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Disulfide bond reductase DsbH</fullName>
            <ecNumber evidence="2">1.8.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">dsbH</name>
        <name evidence="2" type="ORF">Mal33_36760</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.8.-.-" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="1">
        <location>
            <begin position="35"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="168" mass="18403" checksum="34272BB379F01696" modified="2019-10-16" version="1">MSANRSRPTLALAATAAFLFSLSGCNSKPQLSNLMDSFGKAEVQASPEVWDEHTVGLPFVFGYDEGLAKAKAEGRPAMVFLTTTWCKWCKRMSATCLQDPEIRTLLEQNFVLVLVDGDQESAVKRKLKNTGYPHIVFISPDEQILASQNGFAEPDAFKQVIAQALSTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IX61</accession>
    <name>A0A518IX61_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">BON domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_36920</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007055">
        <property type="entry name" value="BON_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04972">
        <property type="entry name" value="BON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50914">
        <property type="entry name" value="BON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021999270" evidence="1">
        <location>
            <begin position="23"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="BON" evidence="2">
        <location>
            <begin position="134"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="214" mass="21820" checksum="BB6533D35FA34DB7" modified="2019-10-16" version="1" precursor="true">MKHLITISILLTAPGLVANVHAQGNAGGNAGTTGQTANGELATIDVDTAFAGGVQRDGTIGASGSTVPAFSTQGQAAAGSTGARSTALGGGAMGGAFGGAFNQLFGAGAQGQSQSNQKTFRTRLRGDIEVDRPSVASRQSAIQNRLVNLPVAARMTGVRLQMNERTAVLSGSVKTEKDRRMAEMLMRLEPGVSKVDNRLIVEGMGELIPPGSAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IX74</accession>
    <name>A0A518IX74_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_36940</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="130" mass="13774" checksum="98B87F1578146B80" modified="2019-10-16" version="1">MKAFSVALIGLAVLLTGCEDQQSQKSEKSDGIDIKWPGGGFSYDAENGVQVDAPGVDVDVKPGQRVDVKAGDVEVNHESGRGVDVKTPNVKVKANHDGDVEVDTPRVRVDRGSDGSLDVSTPESRNQTDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXQ7</accession>
    <name>A0A518IXQ7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_38840</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021991662" evidence="2">
        <location>
            <begin position="19"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="128" mass="12659" checksum="781D45BA709FFCCB" modified="2019-10-16" version="1" precursor="true">MNARFVTLVAAVSLAALTGCTGIGNGFCGGNLGAPCGAGCAAAVNPAYDYAPTPEPGCGCGTDAYSGYSTGGYYEGMGSYSEPSYQGGWQSSQGVPQPGQYSDGGYVVPNGPGTNMAPAPTLPQPNNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXS3</accession>
    <name>A0A518IXS3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Sialidase</fullName>
            <ecNumber evidence="4">3.2.1.18</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_39070</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.2.1.18" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052794">
        <property type="term" value="F:exo-alpha-(2-&gt;3)-sialidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
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        <property type="term" value="F:exo-alpha-(2-&gt;6)-sialidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052796">
        <property type="term" value="F:exo-alpha-(2-&gt;8)-sialidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008152">
        <property type="term" value="P:metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011040">
        <property type="entry name" value="Sialidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026856">
        <property type="entry name" value="Sialidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029456">
        <property type="entry name" value="Sialidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036278">
        <property type="entry name" value="Sialidase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10628">
        <property type="entry name" value="PTHR10628"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13088">
        <property type="entry name" value="BNR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14873">
        <property type="entry name" value="BNR_assoc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50939">
        <property type="entry name" value="SSF50939"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021728468" evidence="1">
        <location>
            <begin position="28"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="domain" description="BNR_assoc_N" evidence="3">
        <location>
            <begin position="257"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="domain" description="Sialidase" evidence="2">
        <location>
            <begin position="362"/>
            <end position="647"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV57892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="684" mass="75043" checksum="6DFE275E6F09DD2D" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXS7</accession>
    <name>A0A518IXS7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_39030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="141"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="159" mass="17381" checksum="3AF13A9223510FD1" modified="2019-10-16" version="1">MSPFSFLEPIMVIAIAGCGLMAGLFFVFSVAVMQALSQLSPAEGLNAMQSINRTILNSVFLTVFFGTAIVCLGLIVCSLGQRQPGWQWAIAGASTYLVGGFVVTATRNVPMNNQLEQFSEPSPRAIEYWRTYQSLWTRWNHVRTIASASAVVMLVISLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXV6</accession>
    <name>A0A518IXV6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">2-dehydro-3-deoxygluconokinase</fullName>
            <ecNumber evidence="2">2.7.1.45</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">kdgK_1</name>
        <name evidence="2" type="ORF">Mal33_39320</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.1.45" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008673">
        <property type="term" value="F:2-dehydro-3-deoxygluconokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PfkB" evidence="1">
        <location>
            <begin position="10"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="286" mass="31275" checksum="6196364B9DD324D7" modified="2019-10-16" version="1">MLFDNFPDGQSILGGAPFNVAWNLQGFGMEPEFVSAIGDDDAGRRITERMQAWQMSTTGMQTNEHPTGEVQVQFQDGQPSYEIVPDRAFDFLKMPKFPVTSSGFALLYVGSLASRNAVSRDTIRQTIAESDLPRFVDINIRQPWFEKKWLHTLLHGAHWVKLSDEELSELTDTPCKTADEIRAGAQRLGVEYGGENFFVTCGSRGAYAITGGELIVADAPTPNPMRDTVGAGDAFAATTIYGLLSGWDLQRTIRTATRFASRVCGLTGATSDDATLYQSVNDGLAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXZ7</accession>
    <name>A0A518IXZ7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_39770</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="492" mass="55958" checksum="1EE8A4044F6732E2" modified="2019-10-16" version="1">MDAADLPRRYRNFIRFHTHVTYPDESERRQQINTAEVIRRLDAIGMQHIPIPTIWDGVHLVDDGRLAGSLEIERRIGLTYRMRMGRIKRFLDDIFHWSQRDTAIYHALASALREIEFDQLEGRTDIDRAIANVALISTVKQALAIGLASDVIAAQVNWALGEVGGLTADEIELLECLPDEDSLQSTDQLDLERMALDRGISQIQLVENLETRDKIASLLSDCFGGVRRETEHKEIHPLSVRRLDIASRMLSEPGLEALVRIARIANEYVGFQPRFEKKMLPAADGDQTRMRMMQSFDELSRMVPAAWALKVASPKYFRYRVATKSFMVREKIKKSDKKQLFYAMLDRSKSMQQGERIYKLIAILMNRLRAVLRREAILGFSFFDSVVHEQVLVDEVSQARQAMQNLHSSFFLGDDTDINLAIREGITRIEAVVADTQAERPELIIVTDGDHGINVKPEELNGIILHAFIVEEVNDDLIELAKATGGVALQQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IY32</accession>
    <name>A0A518IY32_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_40140</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021764430" evidence="1">
        <location>
            <begin position="22"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="324" mass="35776" checksum="CB089CA243670905" modified="2019-10-16" version="1" precursor="true">MRRWHSYTCWVFSLTIALASASTNREAKAEAQWFLSTGAWVPVLPDYKAVAKTSATPVNDVFVDDQTGVGAQLTLGGFYRFGETRTMFESDLQIAGAGSIGSSQTFSDAVPGENYWFPSLDGLGTIAAGSFNPMAVNVDSDVFHLHKYVGLRDHFSLDWIGLGDITIGCGFSWMSFDQDFQTDARIEAGPRGQYIEDLDTNYLGGEFRGTLRQSIFGQICYFDARYGIYEMDADYFGTSRIYLGTGALFSESQVSAGLKQTTTTVDLAVRTDVCIAGWWVRPSIGFKYFDDMAQIVHPQRPGNSPTTLATDSAYLFNGSFEFVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IY72</accession>
    <name>A0A518IY72_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">3-oxoacyl-[acyl-carrier-protein] synthase 2</fullName>
            <ecNumber evidence="2">2.3.1.179</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">fabF_6</name>
        <name evidence="2" type="ORF">Mal33_40400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.3.1.179" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000794">
        <property type="entry name" value="Beta-ketoacyl_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11712">
        <property type="entry name" value="PTHR11712"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ketoacyl_synth_N" evidence="1">
        <location>
            <begin position="10"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="378" mass="39346" checksum="E6E2196DEA06C682" modified="2019-10-16" version="1">MHHLSSKHDSVVITGVGVLSPLGSGFDSLRSALADPPASPPSAPTTGLLASYSGSIDDFGKLPLDRKRSLRKSMKLMNRETQLGVAAAFQAIQDSDLDAAAYAPERVGVCFGAGNVEVRPEDFVAGVQACGESSAEMIEAAWGSLGIPHVDPLWVLRVLPNMPACHIAISYDYRGPNNTITQAEASANLAIQEAKYHLLDGEADAMIVGSTGTTIRIDGASETDGSEGAAAFVIERLERAQQRGATIYGEVLGIGSSCVIDATMVPKPDEAANNAIRASLAQSHLSDNGGVQFTVINDQRGSAAIDRVLESRPTDLLNLSDWIGHVDAGSGAIGLAVALQRLAAADTSATRSAINIGITHNGLASCLTVRNLQPSRAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYW1</accession>
    <name>A0A518IYW1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Macrolide transporter subunit MacA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_42860</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HlyD_D23" evidence="3">
        <location>
            <begin position="53"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="97"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV58268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="292" mass="32061" checksum="DD97FAABD2DF6AB5" modified="2019-10-16" version="1">MWKLRKWFASRIVNVSLAGVILAIVPVVAADPLTNRAANGGYDAFTEPLQSIDVAAAEPGRIAQVFVKPGARVEADSLLMALDTQVLRATRAIAVVQAETTAEVDSLRIEHKRLEHRYQRLLELRSQGAGSPDEVLHAETDAKIAQLRVQTARDRQRIAELEIAEIDARIAMKEIRSPIAGIVTEVVQDVGEYVAGSEPTTVRVVDLSALRAVFYLPTSLATQMQIDQTLTLQLTDSDETVKSTIRHIDPVTNAESGRVGVEVIIANPNNRYRSGLRCRLERPHHSVSPTPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ32</accession>
    <name>A0A518IZ32_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Putative tRNA (cytidine(34)-2'-O)-methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.207</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">tRNA (cytidine/uridine-2'-O-)-methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">trmL</name>
        <name evidence="4" type="ORF">Mal33_43740</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Could methylate the ribose at the nucleotide 34 wobble position in tRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>5-carboxymethylaminomethyluridine(34) in tRNA(Leu) + S-adenosyl-L-methionine = 5-carboxymethylaminomethyl-2'-O-methyluridine(34) in tRNA(Leu) + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:43088"/>
            <dbReference type="Rhea" id="RHEA-COMP:10333"/>
            <dbReference type="Rhea" id="RHEA-COMP:10334"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74508"/>
            <dbReference type="ChEBI" id="CHEBI:74511"/>
            <dbReference type="EC" id="2.1.1.207"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>cytidine(34) in tRNA + S-adenosyl-L-methionine = 2'-O-methylcytidine(34) in tRNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:43084"/>
            <dbReference type="Rhea" id="RHEA-COMP:10331"/>
            <dbReference type="Rhea" id="RHEA-COMP:10332"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74495"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="EC" id="2.1.1.207"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.207" evidence="1"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008175">
        <property type="term" value="F:tRNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd18094">
        <property type="entry name" value="SpoU-like_TrmL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01885">
        <property type="entry name" value="tRNA_methyltr_TrmL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016914">
        <property type="entry name" value="tRNA_cyt/urid_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42971">
        <property type="entry name" value="PTHR42971"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029256">
        <property type="entry name" value="SpoU_TrmH_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="SpoU_methylase" evidence="3">
        <location>
            <begin position="34"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1 2">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1 2">
        <location>
            <position position="153"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1 2">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR029256-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV58356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="183" mass="20477" checksum="02DE725795D545B1" modified="2019-10-16" version="1">MMDNEKSSDTSEPDVPSDSLADVAPCLQVDEPPVHVVLYQPEIPQNTGNIGRTCVAVGAKLWLVRPLGFKIDEHSVRRAGVDYWHMLNLQLVDSIGEVQQALPQRKFWYFSRFARRSLWEAEIDLGDAIVFGRESAGLPEEILDLDSPQAIRIPTTEQVRSLNLSNTAAIAVYEVLRQHGRLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ54</accession>
    <name>A0A518IZ54_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Trehalose utilization</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_43830</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
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        <property type="entry name" value="Isochorismatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029010">
        <property type="entry name" value="ThuA-like"/>
    </dbReference>
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        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06283">
        <property type="entry name" value="ThuA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="SSF52499"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isochorismatase" evidence="1">
        <location>
            <begin position="60"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="domain" description="ThuA" evidence="2">
        <location>
            <begin position="317"/>
            <end position="525"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="538" mass="59812" checksum="06A8FD4C6F84A69D" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ69</accession>
    <name>A0A518IZ69_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ECF RNA polymerase sigma factor SigW</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">sigW_5</name>
        <name evidence="4" type="ORF">Mal33_44000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="2">
        <location>
            <begin position="38"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="3">
        <location>
            <begin position="148"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV58382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="209" mass="24234" checksum="D884DFF736A9B5D3" modified="2019-10-16" version="1">MTATLQSNDAALGYEDVSDEELLLTYRSSGQRILFETLMKRYQREIYSYLRRYLGDAEQAEDAFQLTFLQVHLRAETFEEGRKFRPWFYAIATNQAIDLQRKNRRHRMVSLDRTRNVDDDESKWTEKLVGNDPDPWLVASGRENQDSVQGIVAQLSDSMQKVVQLVYYQGLKYREAADVLGIPVGTVKSRLNAAVSRLNQLWEESQSVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ70</accession>
    <name>A0A518IZ70_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_44020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">Mal33</strain>
        </source>
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        <property type="project" value="UniProtKB-KW"/>
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    </evidence>
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        <source>
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        </source>
    </evidence>
    <sequence length="567" mass="62979" checksum="3FBB775E1BE849BD" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ77</accession>
    <name>A0A518IZ77_9BACT</name>
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    </organism>
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
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                <person name="Mascher T."/>
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            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
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    </dbReference>
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    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="335" mass="37725" checksum="CE3C37200366FC44" modified="2019-10-16" version="1">MEVVRAATLDDWEPLYDLIQRSGFGLTSLRLTKDQLHERLEWSHFAFTRKSERPGGEPYVFVMEDRATGSLVGTSCIFAKTGGYEPFYAYEVVTEQRESEELNVRGSVRSLQLRRIHDGPTEIGSLFLLPAFRGQGRGSLLSLARFSMIAQRPSRFAKEVIAEMRGVSDADGSSPFWEALGRHFFHVDFPVADALSTVSKKFIDDLMPEHPIYWDLLPPAVREVIGEVHEQTRPAKAMLEREGFASRGLVDIFDAGPILHSDRDSIRSVASCRNPKVERGEVPADAKRQIVTTSASRFRAVNSQVHWIDDDHVVLPEATRRALQLSEAEKVWTLG</sequence>
</entry>
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    <accession>A0A518IZ88</accession>
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        <submittedName>
            <fullName evidence="4">Putative periplasmic serine endoprotease DegP-like</fullName>
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        <name evidence="4" type="primary">mucD_8</name>
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        <dbReference type="NCBI Taxonomy" id="2527990"/>
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            <taxon>Planctomycetia</taxon>
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            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
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    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="entry name" value="PDZ"/>
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        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
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        <property type="entry name" value="PDZ_2"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="PDZ"/>
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        <property type="match status" value="2"/>
    </dbReference>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="QDV58400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="409" mass="42859" checksum="A8E0CB477A5B7D6E" modified="2019-10-16" version="1" precursor="true">MFRRFKKSAVLFACPIPLAAALMVQSAAAQQLPEPVPAAPDVIGETPAQPGSSSPLPEPYSLQQQAPQPSAETQKRPSLGVVAEERRDRTGLTVLSVRELSPAAQAGVLEGDILTGLNGVQTNSIEDVSSALTKLRAGDPVAIEVSREGLLFELRAAMSDAPPPSADDVPREIPGAGDPSMGPSRGILGVTVEDASAPLGGAPVLRGARVISVTAQSPAESIGIRPGDTIVSIDGQVMYGARELTTYMQNAQAGESVEIGYYQDRVLRRKKITLADSGQPLPGAVADDRGDMVPGIVIRPGANVGEILQDVGRTLDGILGPRPARQMPRQAPAESFAAPAPPAIPTPAPSSSRRIPTPDAAPAPGAEEQSEVVRLRRQVEQLLERVQQLESQLDKDQQPQESGDGQDSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ94</accession>
    <name>A0A518IZ94_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_44190</name>
    </gene>
    <organism evidence="2 3">
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        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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        <location>
            <begin position="14"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="163" mass="18714" checksum="01719B6B2D2A8F45" modified="2019-10-16" version="1">MSGEDFSNRLDAAIQRGRQRGLHEQAAAKKEAMSEEELRHLHSSYRLSLSDRIEKAVAQLASHFPGFQTETLFGEKGWGAACGRDDLSMERGRRTNRFSRLEMTIRPLNEYMVLELKGKGTVSNKEVFNRSHFTELTEVDVAEFERLIDAWVVEYAERFASQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ98</accession>
    <name>A0A518IZ98_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Calcineurin-like phosphoesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_44300</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032288">
        <property type="entry name" value="Metallophos_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032285">
        <property type="entry name" value="Metallophos_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16370">
        <property type="entry name" value="MetallophosC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16371">
        <property type="entry name" value="MetallophosN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MetallophosN" evidence="4">
        <location>
            <begin position="98"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="Metallophos" evidence="2">
        <location>
            <begin position="224"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="domain" description="MetallophosC" evidence="3">
        <location>
            <begin position="402"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV58412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="579" mass="64640" checksum="C70CD92B49473FFD" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZA1</accession>
    <name>A0A518IZA1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative oxidoreductase UxuB</fullName>
            <ecNumber evidence="1">1.-.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">uxuB</name>
        <name evidence="1" type="ORF">Mal33_44290</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.-.-.-" evidence="1"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="271" mass="27714" checksum="4BD18C96BDDF8E92" modified="2019-10-16" version="1">MSTEIFSLVGSTAVVVGGTGVLGGGMAQALADAGAKVAVVGRSAERGEARVREIEAAGGTAMFQSADALCRDSLTGARDAIAKQLGTPTILINAAGGNHPDATLPPGSDFCKLPQEAWQGVFDLNLVGGVLLPSQVFGESMLAVGKGCSIINIASMAGMIPLSRVVAYSAAKAAVINLTQFLAREWATRGVRVNAISPGFFPADQNRKLLFNDDGSYTERGGQIIGHTPMARFGDANELAGAVVWLAASKASSFVTGQNIVVDGGFSSVTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZS1</accession>
    <name>A0A518IZS1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_46120</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="255"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="280"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="306" mass="34869" checksum="DA05CB7FEED43A43" modified="2019-10-16" version="1">MRWSVRRGTPFGEETWGESHAQRLDLESTLRPRGRPRNLPSNPNKIEKEYLPLCRKGATVNHRSKRTIVTLPKRWGSSLLLVAIALSLFGFPFLIYGDPQGPDATVFMLSLTYVPGFFLLVAVVALFRLRVELEGRRNSRSIRLQLPKHGKLPWTPWMVHEREIPAMEISRVDEVLEAHPTEPDRISRRYILRTKQGDYYFTSLWFSNIEKFRQWCKQSKIPIGEVSTAQLADTERGDAKVPPAGAWAVRSIGKLLKAIAFLTLLASIISLFFVDAEGRWIAVQAFVSAGALLSIAVHLTKIRQRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZU5</accession>
    <name>A0A518IZU5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Inositol 2-dehydrogenase</fullName>
            <ecNumber evidence="9">1.1.1.18</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">iolG_16</name>
        <name evidence="9" type="ORF">Mal33_46320</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.18" evidence="9"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016798">
        <property type="term" value="F:hydrolase activity, acting on glycosyl bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050112">
        <property type="term" value="F:inositol 2-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008152">
        <property type="term" value="P:metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043906">
        <property type="entry name" value="Gfo/Idh/MocA_OxRdtase_bact_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019546">
        <property type="entry name" value="TAT_signal_bac_arc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19051">
        <property type="entry name" value="GFO_IDH_MocA_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01409">
        <property type="entry name" value="TAT_signal_seq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0520">NAD</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022009815" evidence="6">
        <location>
            <begin position="30"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="domain" description="GFO_IDH_MocA" evidence="7">
        <location>
            <begin position="59"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="domain" description="GFO_IDH_MocA_C2" evidence="8">
        <location>
            <begin position="206"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF19051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV58608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="457" mass="50538" checksum="3BA35315219EAF71" modified="2019-10-16" version="1" precursor="true">MSLSRQTTSRRRFLQGTAAAGAAAFVAPAANRAFALQSPNERPVFATIGLRNQGWGITNKSFKFADFAALADVDSNVLGANVEKAAAKQKKKPDAYKDYREILDRKDIDAVMIATPDHWHTKISVEAMYAGKDVYCEKPLTLTIAEGKLIEKVVKETGRVFQVGTMQRTESGQRFLQAIALVKAGRIGTVKKVTCGIGGMVASPVIPVAEVPKEIDWDFWLGPAPKVDYRALPEMRQGYGGGVPLYSNCHYSFRNWHEYSGGKLTDWGAHHVDIACWALGASDTGPSKITPLEYSLPVEYKDGNPVVHDQYNTATSFKIRVDMPNDVEMIINSAGDNGILFEGTEGRFFVNRGKIVGAPVEALKENPLPEGAIEEVYGGPVSENHTANFIDAMKSRKQPISDVWSHNRMLEICHLSNIAMRLDRELKWDPAKREIVGDDQANSFLSREDRKGYEINM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZV7</accession>
    <name>A0A518IZV7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_46510</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="115" mass="12763" checksum="CBCBBB2ADB068040" modified="2019-10-16" version="1">MPMNKQYVVEFFGGPMDGHIEPVAESLNPFVVFPSRVPVRSRGFLAGLFHFWRRPKKQQPSVLAVYELHCVGLQQRYQHVRSIEASGIEIVPIGTQAVISAPRSSQRGPSSTSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J088</accession>
    <name>A0A518J088_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Sensor protein FixL</fullName>
            <ecNumber evidence="5">2.7.13.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">fixL_3</name>
        <name evidence="5" type="ORF">Mal33_47730</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.13.3" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PAS" evidence="3">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="4">
        <location>
            <begin position="72"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="3">
        <location>
            <begin position="124"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="4">
        <location>
            <begin position="201"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="3">
        <location>
            <begin position="414"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="4">
        <location>
            <begin position="487"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="3">
        <location>
            <begin position="568"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="4">
        <location>
            <begin position="617"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="2">
        <location>
            <begin position="682"/>
            <end position="894"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV58748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="897" mass="99546" checksum="C30EEAEEECAE4CFC" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0A7</accession>
    <name>A0A518J0A7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 6">ATP-dependent DNA helicase RecG</fullName>
            <ecNumber evidence="3 6">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6 9" type="primary">recG</name>
        <name evidence="9" type="ORF">Mal33_48020</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the helicase family. RecG subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="3 6"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004609">
        <property type="entry name" value="ATP-dep_DNA_helicase_RecG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045562">
        <property type="entry name" value="RecG_dom3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033454">
        <property type="entry name" value="RecG_wedge"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19833">
        <property type="entry name" value="RecG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17191">
        <property type="entry name" value="RecG_wedge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00643">
        <property type="entry name" value="recG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5 6" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="6" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6 9" id="KW-0347">Helicase</keyword>
    <keyword evidence="6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="7">
        <location>
            <begin position="284"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="8">
        <location>
            <begin position="468"/>
            <end position="625"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV58777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="698" mass="77521" checksum="954D87B786B05E57" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0J6</accession>
    <name>A0A518J0J6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_48880</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021950204" evidence="2">
        <location>
            <begin position="22"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="653"/>
            <end position="680"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="748" mass="79241" checksum="0CDBB6BFF895DA34" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0L2</accession>
    <name>A0A518J0L2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">pknH_2</name>
        <name evidence="8" type="ORF">Mal33_48990</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="114"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV58874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="617" mass="68018" checksum="E35F76EF89A56647" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0X6</accession>
    <name>A0A518J0X6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Silver exporting P-type ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">silP_2</name>
        <name evidence="8" type="ORF">Mal33_49800</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
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</entry>
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                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </evidence>
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</entry>
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        <submittedName>
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    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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                <person name="Jetten M.S.M."/>
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                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022102378" evidence="1">
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            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="142" mass="15035" checksum="EEBC097A26F4E382" modified="2019-10-16" version="1" precursor="true">MNCKANKWRFLCCGIAILAFVSGCGNAGNSSAGFVRFDDGTPVRSGSVEFRSVADGSRYASRIGTDGSFTLTDQDGEPRCPAGEYEIVVVQIVLTEDLAADAHQHGGTVPRRYADYYTSGLTTTRGVADTTPLLVTLATGDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J251</accession>
    <name>A0A518J251_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC-type uncharacterized transport system</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_54410</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025699">
        <property type="entry name" value="ABC2_memb-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019196">
        <property type="entry name" value="ABC_transp_unknown"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13346">
        <property type="entry name" value="ABC2_membrane_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09822">
        <property type="entry name" value="ABC_transp_aux"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="6"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="53"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="90"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="134"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="173"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="201"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="246"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="288"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="937"/>
            <end position="956"/>
        </location>
    </feature>
    <feature type="domain" description="ABC_transp_aux" evidence="4">
        <location>
            <begin position="312"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="722"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="846"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="736"/>
            <end position="751"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF09822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV59406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="972" mass="107784" checksum="2492160252FA0DDC" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J2B6</accession>
    <name>A0A518J2B6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">ABC transporter permease YtrF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ytrF</name>
        <name evidence="9" type="ORF">Mal33_55140</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="335"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="379"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="433"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="8">
        <location>
            <begin position="18"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="7">
        <location>
            <begin position="364"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV59479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="464" mass="50269" checksum="1D9FC27897C56E32" modified="2019-10-16" version="1">MNLFKIAWRNAQQRGLSTLLTTISLALGVGLVVLVLSIHGIVSDAFQRNATVGYNLVVGAKGSPLQLTLNTVYYLSQPVENLPYDYYLEFFGQEERERQLAAYGGHLDEPDRPGKFSLYTGSDSGGLVIPVCLGDYFGEYRVVGTTPAFLDNLKHGPDVDQPYEFREGRNFQTHSEENGFFEAVVGSRVASTMNIKVGDTFNPTHGDPDGKGHDLGFKIVGVLKPTGTPNDRATFVNMEGFYLMEGHAKPSEHGDEEEEAEVEEEVVVAGEEGAVPNTPLPLDQREVTAILLRPSQTMFAMMLQNVINEGLQAQAATPIGEISKLMEQFVDPIRYVLLLITAITCIVAGVGILVSIYNSMNDRRRDIAVMRALGARRGTVMWIILLESGMIAVLGGLLGWIAAHGAIALASGTIEDRTGVPVNFFSTTSAELYVLPLVLGLAAIAGFVPALVAYRTDVSRALAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ILW2</accession>
    <name>A0A518ILW2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_00310</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021964170" evidence="1">
        <location>
            <begin position="25"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="447" mass="47914" checksum="B69CFB985E697AB8" modified="2019-10-16" version="1" precursor="true">MKTIFQRSCLLLGLALATCATADAQGRTRARLFWQDDADATVRYGDFKRQGNEYSLEAKTIDGFPALDVEEQSLVQMQADSGLILIGVRDQADGTIGSGWVAIESGGVEEPHGDHSHWKFPSAPSVLRSVIDTEQGNPAHLYHYGRSFVLANDKSSGMTITTAQRLRDPKPSADRTTFVLGGGGHITLAIAEDHVAYSTWIDRSGENSGRVDVVGLGSNYGKRYEIRCPSGGLHGATINEGKVFLAPADGVCWVPADMQMTGSADDVEVKHLAIGKGSEDKPLRTGAFANLKNHVLFTAGKEADCRLCWIDASSPSPAISTLLIALDEAEGLSTPVVLETRDRRKLALTFAENRSDSSKDRLIVVDLDPNDDGNFSDAKQVQSIAVGPNQIEGHSGHHTVTVLPGRRQVALTNPGEGSIWIVSLTDFKVAAKFDVPGTPTRLIALGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ILZ3</accession>
    <name>A0A518ILZ3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="5">PPIase</shortName>
            <ecNumber evidence="5">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Mal33_00600</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 5">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the cyclophilin-type PPIase family.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000413">
        <property type="term" value="P:protein peptidyl-prolyl isomerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024936">
        <property type="entry name" value="Cyclophilin-type_PPIase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044665">
        <property type="entry name" value="E_coli_cyclophilin_A-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43246">
        <property type="entry name" value="PTHR43246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001467">
        <property type="entry name" value="Peptidylpro_ismrse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="SSF50891"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0697">Rotamase</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022267317" description="Peptidyl-prolyl cis-trans isomerase" evidence="5">
        <location>
            <begin position="21"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="6">
        <location>
            <begin position="30"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV54118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="188" mass="20228" checksum="DBAEDB78DC9F1B45" modified="2019-10-16" version="1" precursor="true">MRNFAAMLAVTLLATATLSAANPVVVDMKTSMGPIQIEMYPDKAPETVKNFVNYANKGFYDGTIFHRVIDGFMIQGGGFTPNMQEKETGAMIQNESANGLKNEKYTIAMARTPNPHSATSQFFINTGTDNGFLDRANARDGFGYCVFGKVTKGTEIVDAIGKVATGNVGPHGDVPRTPVIIEKVTIAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IM08</accession>
    <name>A0A518IM08_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_00730</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021701479" evidence="1">
        <location>
            <begin position="22"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="111" mass="12915" checksum="7CD552E60701DF28" modified="2019-10-16" version="1" precursor="true">MMMRLLLAATICLSFAATAPAEPASAETKEVVKYQLLEWKNKHTRNNDDAEKLIKAFKTLKVEMEVSDHGNHKDVKYRCPKWKQLTVKDHDTAHQWEAWLKKLGFTTIHEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IM35</accession>
    <name>A0A518IM35_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sulfoacetaldehyde reductase</fullName>
            <ecNumber evidence="2">1.1.1.313</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">isfD</name>
        <name evidence="2" type="ORF">Mal33_00810</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.313" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="259" mass="27696" checksum="FB80A47B48D52C9A" modified="2019-10-16" version="1">MTTLITGASSGIGWELAKQFAAGGDDVVLVARSEEKLQKLAVEIRETHRVSATVIRSDFAETDGVDRLCERLRTDEIQIDTLVNNAGFGALGRFAELPVERQTDMLMVNVVALTRLTRLLLPAMLATGKGGILNVGSIAAYQAGPNMSVYYASKAYVLSFTEGLREELAGTGLHVTCLEPGPTETGFGDDSGMGTLDMFSSAAMSAEDVAAAGYRGYRKNDDVVIPGWKNRLMVTSAGFLPRIATRKLVAKMQSVSHAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IME1</accession>
    <name>A0A518IME1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glycine cleavage system H protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">gcvH_1</name>
        <name evidence="3" type="synonym">gcvH</name>
        <name evidence="6" type="ORF">Mal33_02060</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
        <text evidence="3">Binds 1 lipoyl cofactor covalently.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">The glycine cleavage system is composed of four proteins: P, T, L and H.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the GcvH family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005960">
        <property type="term" value="C:glycine cleavage complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019464">
        <property type="term" value="P:glycine decarboxylation via glycine cleavage system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06848">
        <property type="entry name" value="GCS_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00272">
        <property type="entry name" value="GcvH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003016">
        <property type="entry name" value="2-oxoA_DH_lipoyl-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002930">
        <property type="entry name" value="GCV_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033753">
        <property type="entry name" value="GCV_H/Fam206"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017453">
        <property type="entry name" value="GCV_H_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11715">
        <property type="entry name" value="PTHR11715"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01597">
        <property type="entry name" value="GCV_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00527">
        <property type="entry name" value="gcvH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00189">
        <property type="entry name" value="LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="5">
        <location>
            <begin position="21"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-lipoyllysine" evidence="3 4">
        <location>
            <position position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR617453-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV54256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="127" mass="13820" checksum="AE8E8BEF5A2EFE43" modified="2019-10-16" version="1">MNQEELLYAETHEWVHVESGVATIGITAFAAEQLTDLVYMELPEVGRQLNVGEEFGEVESVKAVSPLYSPVAGEVIEINTELPSKLDLLGSDAFGAGWMIKVRVSGEPDAAKLLNHEAYQKQCAEGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IME4</accession>
    <name>A0A518IME4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Aminomethyltransferase</fullName>
            <ecNumber evidence="3">2.1.2.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Glycine cleavage system T protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">gcvT</name>
        <name evidence="9" type="ORF">Mal33_02070</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(6S)-5,6,7,8-tetrahydrofolate + (R)-N(6)-(S(8)-aminomethyldihydrolipoyl)-L-lysyl-[protein] = (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + (R)-N(6)-dihydrolipoyl-L-lysyl-[protein] + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:16945"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="Rhea" id="RHEA-COMP:10492"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="ChEBI" id="CHEBI:83143"/>
            <dbReference type="EC" id="2.1.2.10"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GcvT family.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.10" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004047">
        <property type="term" value="F:aminomethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006546">
        <property type="term" value="P:glycine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006223">
        <property type="entry name" value="GCS_T"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028896">
        <property type="entry name" value="GCST/YgfZ/DmdA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013977">
        <property type="entry name" value="GCV_T_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006222">
        <property type="entry name" value="GCV_T_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029043">
        <property type="entry name" value="GcvT/YgfZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027266">
        <property type="entry name" value="TrmE/GcvT_dom1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43757">
        <property type="entry name" value="PTHR43757"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01571">
        <property type="entry name" value="GCV_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08669">
        <property type="entry name" value="GCV_T_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101790">
        <property type="entry name" value="SSF101790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00528">
        <property type="entry name" value="gcvT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GCV_T" evidence="7">
        <location>
            <begin position="10"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="GCV_T_C" evidence="8">
        <location>
            <begin position="293"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV54257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="372" mass="40663" checksum="82F14699A4A34386" modified="2019-10-16" version="1">MTDSIASTPLTSWHRAAGATMSPFAGFDMPIHYGSIVTEHNACRNAATLFDVSHMGRIRFDGDRSAELLDRLLTRRVSDLAPGGIRYSLMCNEEGGILDDVLVYHIEKPSGGRFHMLVVNASNRQKIIEWLTPRMAEYPDVICTDRTELTSMIALQGPLAMATVEGLFKHPADKLGYYHSYVTEQFNKPVIVSRTGYTGEDGLELITRADEAARIWENLMLAGRKHGIQAAGLGCRDTLRLEAGMPLYGHELSESIDPISAGLGFACSFKDRTFIGSEALAKIKAAPQQSIRVGIRVEGVRPAREGCQILDANEQNIGAITSGTVSPTLQYPIAMGYVAAEHSEIGSPLTIDIRGKRAAATVVPLPFYKRNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMK1</accession>
    <name>A0A518IMK1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">TPR repeat-containing protein YfgC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">yfgC_1</name>
        <name evidence="8" type="ORF">Mal33_02540</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the peptidase M48 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001915">
        <property type="entry name" value="Peptidase_M48"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01435">
        <property type="entry name" value="Peptidase_M48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1 6" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase_M48" evidence="7">
        <location>
            <begin position="107"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV54304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="279" mass="29916" checksum="C77CE954ABED357D" modified="2019-10-16" version="1">MPFGFGRRSNSGLKLRLMIAAGLALFSFISYLSTGQRNPITGEKQRVAMSPDQEIALGLQAAPEMAAQHGGLHPDPQARAHVDQVGQRLLSGLDDYVRVKQGTNPFQFKFHLLKDPQTINAFALPGGQVFITAALYSRLQTEGQLAGVLGHEIGHVLSRHGAQRLAKQKLTSGLVGAAGVAGGDISSAQLAQAIGQMLNMKYGRDDELESDRWGVLLTAQAGYDPRAMLGVMQILDEASGSNGPPEMMSTHPKPANRQAYIQEVLRSVFPNGIPEGLDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IN20</accession>
    <name>A0A518IN20_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_04400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011467">
        <property type="entry name" value="DUF1573"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07610">
        <property type="entry name" value="DUF1573"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="412" mass="45355" checksum="6C2C01B9571FA43F" modified="2019-10-16" version="1">MRLLAIIALALIAGISLGKLTGSRQTTESIDHFGPFTEVEDFDLEQLPQYLSSLIPDNVGQIELIGEKDFDFGVMHRNTEGEHAFKIRNVGTGPLRLEVTGSTCKCTVGELENESIAPGETSEIKLTWKTRSNTTEFAQTATIKTNDPNNVEVKLTVHGTLVETLLTEPTDWSVGNVTSGEPIDLEFTAYSYADAPIEIVSAQFLDETVQALTEVDWTVRKPDEKTDGKHHAALQAFEFKVKVKPGLRQGSLNHVLRVHYKNDDLDEDSPSFDMNLSGNIVGPLRLLGGSKLEQSDKGDGGGYRFNFGTVRQGDPGNERIHLVIRGKEYEDLVVKVGEIKPDNVFAVSLGEENRRGTLRSIPIDIQIKPEAPLGIVRGMKSLDTGYVMLEPQNSNLSPLKLWLTVEVTAVDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IN31</accession>
    <name>A0A518IN31_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Flagellar assembly protein H</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_04470</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010106">
        <property type="entry name" value="RpnA"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01784">
        <property type="entry name" value="T_den_put_tspse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0966">Cell projection</keyword>
    <keyword evidence="1" id="KW-0969">Cilium</keyword>
    <keyword evidence="1" id="KW-0282">Flagellum</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="320" mass="36577" checksum="007862FEDCFD3F27" modified="2019-10-16" version="1">MALGISPLVDFAFKKIFGSPENVRALIGLLNAVLDRASPIIAVEILNPFNYQEFADAKQIVLDVRARDDQGRSLNVEMQVSRVGGLLQRLNYYACSLYVDQMQRGGNYWTLRPAISICFLNDQLFRDTQQPHHWFEQVDMTSGRRLTGGIEVHTIELPKYNLLATKISQASRIEQWVYFLLKADQHETAELRQMFPALEFQAAIDAIDRIAAKTEDRVMYDEREKAIRDQQWLMEGTRMEARQEGLQQGMQQGLQEGMQQGLQEGLQKGRQAGVLAGQIQLLQRLLQQPEQPLEELLQLPTEKLTAQHADLQSQARLRNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IN81</accession>
    <name>A0A518IN81_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Mal33_04980</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0324 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018383">
        <property type="entry name" value="UPF0324_pro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30106">
        <property type="entry name" value="PTHR30106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03601">
        <property type="entry name" value="Cons_hypoth698"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="104"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="130"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="162"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="217"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="246"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="278"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="310"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="342"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="384"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="422"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="451"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV54543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="483" mass="51460" checksum="67D523968C417ECF" modified="2019-10-16" version="1">MSNEPGSQPSDNDAAPDGDDTVTLPPERHSLWTDMRTAEDWWAIWCAALLLVFAFGAVWLGRPDGLAESIGMGEPLEVVSPLKAYLSKPGSWEADPLASLDGKLVGIGGVFLVLAVLCGFAMWCRGKSAAAFLAGFPIVFLLATLAYVLAGQSVLKAYNLEYALWALLVGLIISNTIGTPAFLRPAIMTEFFIKTGLVLLGAEVLMSRLLALGLPGVFVAWVVTPIVLVSTYIFGQKVLKIPSRSLNMVISADMSVCGVSAAIATAASCKAKKEELSLAIGMSLSFTVIMMVVLPAIIKATEMSPTLGGAWLGGTIDSTGAVAAAGAVLGDEALEVAATVKMIQNILIGVTAFCVAIYWVTYVERDPSAPRVGASEIWYRFPKFVLGFVAMSILFSVLYSTMTAGPELINAMIKGSTKTLRGWLFCLAFVSIGLETNFKQLLPQLKGGKPLILYVCGQTLNLCLTLLMAYLMFEVVFAPVVEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IND2</accession>
    <name>A0A518IND2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transglutaminase-like superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_05270</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002931">
        <property type="entry name" value="Transglutaminase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01841">
        <property type="entry name" value="Transglut_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00460">
        <property type="entry name" value="TGc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TGc" evidence="2">
        <location>
            <begin position="446"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="555" mass="61174" checksum="866BC2AB659878F2" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INV1</accession>
    <name>A0A518INV1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">EF hand</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_07300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13202">
        <property type="entry name" value="EF-hand_5"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="SSF47473"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="2">
        <location>
            <begin position="386"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="241"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="338"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="338"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="444" mass="48466" checksum="5F86D60AEE837503" modified="2019-10-16" version="1">MFSRQALIGSLACLLAIIASDGWSQPPFGRGGGDRGGDRGDRGGDRGGRGGRGGGDPSSFIDRLDRNGNGMIDTDEMQGPAKYMIDRMARENPKIDSSKPISLDALKQGFEKMRGQRDSGRGSDRGSDRDRGRDRDQERREVDEAMEVDQLVMGFEPEAPADPVPGFGSVGELFAVRVTPGDERTAAERMGRYDRNKNGYLDKEEMSGNWFGNPLDFDRNGDGRLSPAELAVRYARRRVAEEEVKEERSRRESKREPEKKPASDEDPFGGRKSYRRIVAESDAGLPGWFNERDSNRDGQVMMAEYASVWNDDLISDFFKFDLNSDGVITASECYSAVESGVSPGSSVSSSSSPSARSESAMTSTTSKPAAAATPAAAGSGAALDPKYVGYAKRIIERSDKNKDGVLTAAEWKDMLLDISPADANKDARITVEEYATWLKAKSTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPB6</accession>
    <name>A0A518IPB6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_08950</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="95" mass="10863" checksum="EC213B784747F3C5" modified="2019-10-16" version="1">MRDALFAARSIGFVMSENLHRRHLEPTQRAACALRARDLYDQRAKERQVRKSQNSVQEDLPEKNQQARDEVGKVFGVSGGLVEHVKRITTTESRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPL2</accession>
    <name>A0A518IPL2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Flagellar FliJ protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Mal33_10040</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the FliJ family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009288">
        <property type="term" value="C:bacterial-type flagellum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044781">
        <property type="term" value="P:bacterial-type flagellum organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012823">
        <property type="entry name" value="Flagell_FliJ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02050">
        <property type="entry name" value="FliJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1005">Bacterial flagellum biogenesis</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="12" id="KW-0966">Cell projection</keyword>
    <keyword evidence="7" id="KW-0145">Chemotaxis</keyword>
    <keyword evidence="12" id="KW-0969">Cilium</keyword>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="12" id="KW-0282">Flagellum</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="102"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QDV55036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="153" mass="17328" checksum="A9BCBD470432FBCD" modified="2019-10-16" version="1">MKGFKFRLASLLNLRCSERDAARRGVADATQALGILETQIADKSSELENLKTQRGTYLQGQISVDQLLAQGRHEILVEQEKATLQQQVGQVNVELRKRELILQTADQEVKRIEKLRDRALQTYRDTEQARLQAEMDEVAAVLHQSAENSLRGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPL7</accession>
    <name>A0A518IPL7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_10090</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="72" mass="8208" checksum="2549C27CD69D3E81" modified="2019-10-16" version="1">MIDTLEPQSSVVARNRLHESPITELRDLEIVEDGECLCISGRVRSFYHKQLAQETVRQTAPGWTVVNRVDVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPR5</accession>
    <name>A0A518IPR5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_10420</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007434">
        <property type="entry name" value="FemAB-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04339">
        <property type="entry name" value="FemAB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="417" mass="47158" checksum="ED457AE80066D017" modified="2019-10-16" version="1">MTNETIAFHYLIFDSADAVPVEAWNSVQQRVGDPFCDLRFIRVVETSMAADTRCWPVVFYDGKRPVAISCISRYRVDAGVLTGGPLQKLIGFVRRVLPSFLFLKIVFAGLPVSAGQRGLVMLPDTNHQEVVRLMDDALATIARREAVGLIVIKEFEQTDSDWADQFSRQYRYYKADSLPMNRLELAFDSFDDYLAARSSRSRSSIRQSRRRLRDTGCQLIQLPGGSEAIERFNDEAHRLYLAVLGKSHSRLETLPAEFFRELARQFGDAAHFTFIYQSERLVAVSCSLKGDDVFQMMFCGIDYSLNDQAHLYFNIMFSDLDIGFRQHVSRINVGQNGDTFKARLGCRQIPLSIYIKGRNLFRPLLWMFQRWFLPAAPLLAPIETLSGKRSPQVSGKTTSTVAPPATVARATVLGLLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPW9</accession>
    <name>A0A518IPW9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_10910</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021309">
        <property type="entry name" value="DUF2892"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11127">
        <property type="entry name" value="DUF2892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="72" mass="8411" checksum="9E65386F6F5B379A" modified="2019-10-16" version="1">MNNKRHGQIEFPDRLQRLVIGTLLMLLTLWGLSERFDWTRVVALTLQLELLLTGIAGWCPIYWGCRTFIPPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQ58</accession>
    <name>A0A518IQ58_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_12060</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="636" mass="69554" checksum="417DCAD6B1570B62" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQB3</accession>
    <name>A0A518IQB3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF1080 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_12320</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010496">
        <property type="entry name" value="3-keto-disaccharide_hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06439">
        <property type="entry name" value="DUF1080"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021822091" description="DUF1080 domain-containing protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1080" evidence="2">
        <location>
            <begin position="27"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="210" mass="23684" checksum="295E49E4252D6BDF" modified="2019-10-16" version="1" precursor="true">MKHLFHCSIALLFVSALARPSVAQEEGFTQLFDGKSLSGWKASENTDSWSVKDGTLMCDGPRSHLFYEGELAPFKDFHFKADVMTTPGSNAGIYFHTKFQQEGWPVKGYECQVNVTHKDPKKSSSLYAVDNVAAPPVKDNEWYTQEIIVKGRHIVLKLNGETMVDYTEPENKQADNSGFDRRLSEGTFALQAHDPDSVVYFKNLRVKKLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQC5</accession>
    <name>A0A518IQC5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">PD-(D/E)XK nuclease family transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_12230</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010106">
        <property type="entry name" value="RpnA"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01784">
        <property type="entry name" value="T_den_put_tspse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="296" mass="33972" checksum="D88BC63F459119FD" modified="2019-10-16" version="1">MPLGISPLVDFAFKKIFGSPENVQALIGLLNAVLCLEHPIVSVEILNPFNYQEFKEAKQIILDVRARDTTGRMLNVELQVAAFPGLLQRLTYYACSMYVEQLERGDDYHRLCSAISICFVNQNLHRGSAQAHHWYQMVDRESGRTFGDGIEVHTVELPKYNLREETIAVASPLEQWAFFLLNAHRYDADRLRELLPAVEFQTAIIVVERIAEKTEDRVMYDQRERAIRDYEWSIASARDEGREQGMEKGSIAGQIQLTQDLLDEPPQSLSDLQQLSIEELNQLLAELRTRLHDRLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQF6</accession>
    <name>A0A518IQF6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_12970</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007236">
        <property type="entry name" value="SlyX"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04102">
        <property type="entry name" value="SlyX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="4"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="73" mass="8662" checksum="52EF5C9645A13C1E" modified="2019-10-16" version="1">MNPSESMQQQINKLQETVAFQQRTIDHFQEALLQIRRELDNATRQLEQQKGRVHWLSENIAGDNLPHEKPPHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQQ9</accession>
    <name>A0A518IQQ9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative enoyl-CoA hydratase echA8</fullName>
            <ecNumber evidence="3">4.2.1.17</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">echA8_1</name>
        <name evidence="3" type="ORF">Mal33_14050</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.17" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004300">
        <property type="term" value="F:enoyl-CoA hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.12.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018376">
        <property type="entry name" value="Enoyl-CoA_hyd/isom_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014748">
        <property type="entry name" value="Enoyl-CoA_hydra_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00166">
        <property type="entry name" value="ENOYL_COA_HYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="261" mass="27603" checksum="11C50CC374020EE1" modified="2019-10-16" version="1">MTAVNVLVNSPSGTIQLTRPDQRNALDRSAVEQISQAFFDLHQEKKVRGVILTASGTDFCAGLDLKEMHQTASGDPNSALGAWHDDWTQLRDLLETMLRFPKPIIAAIDGTALGAGLGLALAADLIVAAPSATFGVPAVRRGLISGVVSPLLCFRSGGKTAARMMLTGQSIDAQEALRLNLIDEIVDADKIWVRANELVAECAAAPAEAIQLSKRLLNETIGETLLTQMSVGAAMGATACTTEAAAEGLAAFKEKREPNWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRE8</accession>
    <name>A0A518IRE8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_16470</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="36" mass="4201" checksum="1991FA4D4EB9AF2D" modified="2019-10-16" version="1">MNPAFQSIFRNFAFRSFFAKGPCLFLLTCVRRGELD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRH9</accession>
    <name>A0A518IRH9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Elongation factor P--(R)-beta-lysine ligase</fullName>
            <ecNumber evidence="3">6.3.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">epmA</name>
        <name evidence="3" type="ORF">Mal33_16320</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="6.3.1.-" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004824">
        <property type="term" value="F:lysine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006430">
        <property type="term" value="P:lysyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004525">
        <property type="entry name" value="EpmA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00462">
        <property type="entry name" value="genX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="2">
        <location>
            <begin position="15"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="327" mass="36693" checksum="20C34C2CACA4387D" modified="2019-10-16" version="1">MIEPPFQSTAAIETLRQRAAILRSIRGFFDDAGFFEVQTPTLSSETMVDLHIDPVTVAREALQLSLPHAHSDLYLQSSPEFAMKRLLACGADAIYQICPAFRAGERGTNHNPEFMMLEWYRMGDRFEEGIQLLSQLVDRVTDRPACQQMTYQAAFEAFAQFDPLTATLPQLREAAARLGIDLTGLDFEHVDDWLNLIFDHAVVPNLGRGQPTILTHYPSSQAALALICRDDPRTAERFELFIDGIELANGYGELLDAEELLRRCDENNRARMEMGKPGLPMPRQLYRAMQHGISTCSGCALGVDRFVAVLLGKRELSETLTFPIDRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRN1</accession>
    <name>A0A518IRN1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_16820</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="211" mass="22783" checksum="87E0F942EF272832" modified="2019-10-16" version="1">MTSLPTSPRIPASMRVSTRLKALATADESEQPATTTWIDPAHGTASVAATPPLRCLAQSIVNAADQAAQTPILVPGKRVVLEPELFVALSSELIDIARRPIRIEALSPAAGGWAAIHLLRSYRRIVNQLAADVPYDVDVVEMNRISRPAGPNRPLFIGLATSSAMLRWLPTASCYRFLMLESNTRTPLPEGTQASVERFHLTAINGGNAKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IS74</accession>
    <name>A0A518IS74_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Phosphoribosylformylglycinamidine synthase subunit PurL</fullName>
            <shortName evidence="8">FGAM synthase</shortName>
            <ecNumber evidence="8">6.3.5.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Formylglycinamide ribonucleotide amidotransferase subunit II</fullName>
            <shortName evidence="8">FGAR amidotransferase II</shortName>
            <shortName evidence="8">FGAR-AT II</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Glutamine amidotransferase PurL</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Phosphoribosylformylglycinamidine synthase subunit II</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 12" type="primary">purL</name>
        <name evidence="12" type="ORF">Mal33_19280</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>ATP + H2O + L-glutamine + N(2)-formyl-N(1)-(5-phospho-beta-D-ribosyl)glycinamide = 2-formamido-N(1)-(5-O-phospho-beta-D-ribosyl)acetamidine + ADP + H(+) + L-glutamate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:17129"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:147286"/>
            <dbReference type="ChEBI" id="CHEBI:147287"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole from N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the FGAMS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.3" evidence="8"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00128"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004642">
        <property type="term" value="F:phosphoribosylformylglycinamidine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.650.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00420">
        <property type="entry name" value="PurL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010074">
        <property type="entry name" value="PRibForGlyAmidine_synth_PurL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041609">
        <property type="entry name" value="PurL_linker"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010918">
        <property type="entry name" value="PurM-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036676">
        <property type="entry name" value="PurM-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016188">
        <property type="entry name" value="PurM-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036921">
        <property type="entry name" value="PurM-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036604">
        <property type="entry name" value="PurS-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43555">
        <property type="entry name" value="PTHR43555"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00586">
        <property type="entry name" value="AIRS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02769">
        <property type="entry name" value="AIRS_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18072">
        <property type="entry name" value="FGAR-AT_linker"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55326">
        <property type="entry name" value="SSF55326"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56042">
        <property type="entry name" value="SSF56042"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82697">
        <property type="entry name" value="SSF82697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01736">
        <property type="entry name" value="FGAM_synth_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 8 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="7 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 8" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FGAR-AT_linker" evidence="11">
        <location>
            <begin position="186"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="domain" description="AIRS" evidence="9">
        <location>
            <begin position="283"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="domain" description="AIRS_C" evidence="10">
        <location>
            <begin position="419"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="domain" description="AIRS" evidence="9">
        <location>
            <begin position="675"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="domain" description="AIRS_C" evidence="10">
        <location>
            <begin position="802"/>
            <end position="945"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="231"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="303"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="299"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="301"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="324"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="325"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="458"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="486"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="718"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="755"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="758"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF18072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QDV55949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="972" mass="105249" checksum="914F30E5B8B12BE6" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IS88</accession>
    <name>A0A518IS88_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative GTP-binding protein YjiA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_19230</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003495">
        <property type="entry name" value="CobW/HypB/UreG_dom"/>
    </dbReference>
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        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02492">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="cobW" evidence="1">
        <location>
            <begin position="8"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="365" mass="39454" checksum="D233EBEDC0DEC4BB" modified="2019-10-16" version="1">MSTPIRFIMIGGFLGAGKTTLIQQLARRFQADGKHVCIVTNDQAAGLVDTELLKSQGFEVNEVAGSCFCCNFDGLTDAMDEFESRRRPDVILAEPVGSCTDLIATIAIPMMEQLGEKFVHSPYAVILKPKHGLKILSGTGGGFSEKAEYIFRKQLEESEIILLNRIDELSAGEVEELKRLVDQQYPGRQVICISAKTGENLDSLHHAFQQLASPRDATMEVDYDVYADGEAELGWLNATATLESTASIPLDRVAIELVEHLRRSLSQVGAEPGHLKVLCSGGDSVSVANLIDSDSSTVLSVSSEASAAKVTAIINARVRLAPEQLSTLVNEAVAATAKLFDASADVQQLESFRPGRPTPTHRVKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISD0</accession>
    <name>A0A518ISD0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Na(+)-translocating NADH-quinone reductase subunit E</fullName>
            <shortName evidence="9">Na(+)-NQR subunit E</shortName>
            <shortName evidence="9">Na(+)-translocating NQR subunit E</shortName>
            <ecNumber evidence="9">7.2.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">NQR complex subunit E</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">NQR-1 subunit E</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9 10" type="primary">nqrE</name>
        <name evidence="10" type="ORF">Mal33_19710</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a ubiquinone + H(+) + n Na(+)(in) + NADH = a ubiquinol + n Na(+)(out) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:47748"/>
            <dbReference type="Rhea" id="RHEA-COMP:9565"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="7.2.1.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="9">Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the NqrDE/RnfAE family.</text>
    </comment>
    <dbReference type="EC" id="7.2.1.1" evidence="9"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009276">
        <property type="term" value="C:Gram-negative-bacterium-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016655">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022904">
        <property type="term" value="P:respiratory electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006814">
        <property type="term" value="P:sodium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00429">
        <property type="entry name" value="NqrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003667">
        <property type="entry name" value="NqrDE/RnfAE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010967">
        <property type="entry name" value="NqrE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30335:SF1">
        <property type="entry name" value="PTHR30335:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02508">
        <property type="entry name" value="Rnf-Nqr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006102">
        <property type="entry name" value="NQR_DE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01940">
        <property type="entry name" value="nqrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0520">NAD</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0915">Sodium</keyword>
    <keyword evidence="9" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="4 9" id="KW-1278">Translocase</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <keyword evidence="7 9" id="KW-0830">Ubiquinone</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="39"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="85"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="113"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="148"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="180"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV55992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="204" mass="21996" checksum="23C9AC923E9643FD" modified="2019-10-16" version="1">MNESLMTIFMKAVFIENLALAFFLGMCTFLAISKNVKTAVGLGLAVIVIQSITVPANNLIYTYLLKEGALARFLGSEYATLNLEFLGFISYIGVIAAMVQILEMVLDRFFPPLYNALGIFLPLITVNCAILGGSLFMVQREYDFAQSVTYGLGSGVGWALAIAALAGIREKMKYSDVPPGLRGLGITFITVGLMAMAFMAFGGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISD1</accession>
    <name>A0A518ISD1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_19740</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018699">
        <property type="entry name" value="DUF2203"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09969">
        <property type="entry name" value="DUF2203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="154" mass="17192" checksum="BBAC1491DCE8F4C2" modified="2019-10-16" version="1">MTTTAAATRWFTPAKADKTLPLVSAIVSDIKELREAVKLRQSRVDEVLMSRPDASSGPYHEELEAMRRSLDEDRRQIRAFISELTAIGAEIVEGDDSAVEFPAWVEDRAVRLRWSLNDPGVSSWRELADPITTDRDIDSVLFGEGPDIASYSGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISJ3</accession>
    <name>A0A518ISJ3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_20340</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="213"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="258"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="570"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="145"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="339"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="24"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="267"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="309"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="595" mass="67537" checksum="638637FD4CB0C9BB" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISK3</accession>
    <name>A0A518ISK3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Chaperone protein DnaK</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">dnaK_1</name>
        <name evidence="5" type="ORF">Mal33_20290</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="PTHR19375"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00297">
        <property type="entry name" value="HSP70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV56050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="609" mass="65729" checksum="DC94BCD9C1C4C215" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISM3</accession>
    <name>A0A518ISM3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">N-(2-amino-2-carboxyethyl)-L-glutamate synthase</fullName>
            <ecNumber evidence="5">2.5.1.140</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">sbnA</name>
        <name evidence="9" type="ORF">Mal33_20640</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Siderophore biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the cysteine synthase/cystathionine beta-synthase family. SbnA subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.140" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00989"/>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016765">
        <property type="term" value="F:transferase activity, transferring alkyl or aryl (other than methyl) groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006535">
        <property type="term" value="P:cysteine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001216">
        <property type="entry name" value="P-phosphate_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023927">
        <property type="entry name" value="SbnA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03945">
        <property type="entry name" value="PLP_SbnA_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00901">
        <property type="entry name" value="CYS_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PALP" evidence="8">
        <location>
            <begin position="30"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00016985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV56085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="358" mass="38704" checksum="A873D2BE482902EF" modified="2019-10-16" version="1">MAVLEQENGVAEECQSASRPHVQSADGILDCVGQTPLVQMRRYLEESSVELYAKLESANPGGSAKDRPATRMLHHAIRQGELAEGATVIESSSGNMGIGLAQACRFHGLRFMCVVDPHAQPQNVAIMRALGAEIVRVERQVDGSFLAARLQRVRELLEVTPNSYWPNQYANRQNPIAHLNGTIREIDRDTGGDIDYLFVATSSTGTAQGCRDYLRRHRRNTKVIAVDANGSVLFGGSPGERLIPGLGAGHEPALARDQTFDQIVRVSDIDCVVGCRRAAGREAMLVGGSAGGVLEVVRSMEANLRGKRCVAILHDSGTRYLDTVFNDDWLQSALGTNADEVEARIGSPALSSTEARSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IT01</accession>
    <name>A0A518IT01_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase</fullName>
            <ecNumber evidence="3">2.4.2.53</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">arnC_1</name>
        <name evidence="3" type="ORF">Mal33_21980</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.4.2.53" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0099621">
        <property type="term" value="F:undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="233"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="267"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_2-like" evidence="2">
        <location>
            <begin position="4"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="324" mass="35875" checksum="3BCAC59EE0531AF2" modified="2019-10-16" version="1">MDLSIIIPIFNEADSVRPLYDRLTEVMPELPAATEIVFVDDGSTDGSSQRLDEIAARDGRVTVVHFRRNYGQTAAMQAGLEQARGRVLVTLDGDLQNDPHDIPAMLDAIDQGADLVHGWRKDRHDKWLTRKLPSLIANRLISRVTGLPIHDLGCTLKAIRAEVADELDLYGEMHRFIPVLAHARGARCHEMVVAHHARQFGTSKYGLSRTTRVVLDLITVKFLIDYMDRPMKLLGRLALAALAVSGFAGLGVAAMKLFSGIDMTGNPLLLLTVFMGIVSLQFFGLGLLGEMNTRLYYQRSSRRPFAIRSINQSANQTVAMNRAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IT06</accession>
    <name>A0A518IT06_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phosphate-selective porin O and P</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_21910</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023614">
        <property type="entry name" value="Porin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010870">
        <property type="entry name" value="Porin_O/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07396">
        <property type="entry name" value="Porin_O_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="494" mass="54293" checksum="78C12080A3DC8FFC" modified="2019-10-16" version="1">MDSDVPYRPLLTLDPDVRFLPVIASIVALIVSQDSVPAIGQESMIASNAVAPASYDAAAAGTTPAADQVCDIGDPRSPWTPGDGVSASAQLRRFSDSIRVGYDDGFVIASLRERDLETEAFPFRLKVNGWGQLRHTASDVALPNTDLNQFQMKRARLILSGNAFLPDLTYFTQFDGRSSSGDDMRLLDFYLSYDIGHSQFGFEKGTFGFRAGKYKMPFTMARWLSGKEFEFSDRSVASTYFDVNRSLAVGLFGESKHTAIPIEWETAIFNGFVTGGAETGSSGNLDDNFAYSIRLQGYPIGDWGDSQLADFESHDRLAMRVGCAFAGTTISRNGSTEFNTPRVVDSGQTFASILPLAVDSYHVSQFALDASLKWRGWSSTMEYYFRNLSDFEGAGIPSLLDHGFWFQLGYFVVPEKLQVLTRWSRVDGDSGTLGASDQSTDEVGAGLAWYLRGNRAKIVTDVTRLDGAPINSSALDVNPGDRGWLFRTQMQFSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITF3</accession>
    <name>A0A518ITF3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Divalent-cation tolerance protein CutA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">cutA</name>
        <name evidence="2" type="ORF">Mal33_23580</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CutA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010038">
        <property type="term" value="P:response to metal ion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004323">
        <property type="entry name" value="Ion_tolerance_CutA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011322">
        <property type="entry name" value="N-reg_PII-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015867">
        <property type="entry name" value="N-reg_PII/ATP_PRibTrfase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23419">
        <property type="entry name" value="PTHR23419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03091">
        <property type="entry name" value="CutA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54913">
        <property type="entry name" value="SSF54913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="108" mass="12260" checksum="EAFEA3B311DDC39D" modified="2019-10-16" version="1">MDGFLLITTTTPTEDEARRIASRLIELRYAACVQVEGPISSHYRWEGSVHCDPEFRLSIKTVGSRYDEVERTIAELHSYQQPQIIATPIVAGAEGYLNWLTEQTQTEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITI5</accession>
    <name>A0A518ITI5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_23940</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="189" mass="21581" checksum="A26E9239E2E81FDF" modified="2019-10-16" version="1">MLETPEATDQRTDIKTRLASQAAERQHQLRTACFAIATGEQVDSDFVLDLCSQLGVDENAFGFMMRLADREGKRQEIERKAEAAFVAKSAAYKRVRELAEAEKPIVEKYEKWLRDNRPKGEPTAAETKAIRKQRAPVLDIQDDLTEARRIADSRNREHASLSDSLNYFDSETRKLVDKCRGEHPALCWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITZ3</accession>
    <name>A0A518ITZ3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Outer membrane efflux protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_25500</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021840781" evidence="3">
        <location>
            <begin position="23"/>
            <end position="870"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="57"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="123"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="157"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="177"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV56558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="870" mass="94799" checksum="A942CAC147944036" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IU01</accession>
    <name>A0A518IU01_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Plasmid stabilization system protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_25610</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2310.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007712">
        <property type="entry name" value="RelE/ParE_toxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035093">
        <property type="entry name" value="RelE/ParE_toxin_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05016">
        <property type="entry name" value="ParE_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1277">Toxin-antitoxin system</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="111" mass="12647" checksum="7D6809547BCF8A55" modified="2019-10-16" version="1">MNHRLIILPQAQADVQRNALWWATHHSSEQAARWLDAVQSQLESIAEFPESHSLAAENDEFAYEIREKRVGLGARPRYRAVFTLADDAIYVLAIRAAEQNRLTEDQVGFDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IU07</accession>
    <name>A0A518IU07_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">YceI domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_25660</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007372">
        <property type="entry name" value="Lipid/polyisoprenoid-bd_YceI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036761">
        <property type="entry name" value="TTHA0802/YceI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04264">
        <property type="entry name" value="YceI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00867">
        <property type="entry name" value="YceI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101874">
        <property type="entry name" value="SSF101874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021842958" description="YceI domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="domain" description="YceI" evidence="2">
        <location>
            <begin position="35"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="200" mass="21030" checksum="A68BB4817592DB6B" modified="2019-10-16" version="1" precursor="true">MKKLASLLGICLLSTTCFAQATATTLKPVALQAGTAAISPANSRIDFVGTHEGDKPDPRKGGFGKFTGQAKVAADGSLQSIAWEIETGSLFTEIPKLTGHLKNSDFFDVREYPKASFQSTSVAAGSGEGNYIVTGDLTLLKATKSIKIPVSVDVSAEGLTLHSKFKIDRTQFGMNYGQGKVSNDVQMTVAIGQPTEAAGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IU32</accession>
    <name>A0A518IU32_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_25860</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="108" mass="11798" checksum="139DFEA90AE236CA" modified="2019-10-16" version="1">MIADITLALADKCIAQRRSNPPQQISHLGVKLRCKYQHEAQASEFSLFSHTGATLSRVEFESLACASCWYALIVVRFGAYAFSETSQAVEHAVGLLDSWHIGVADAVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IU95</accession>
    <name>A0A518IU95_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Multidrug export ATP-binding/permease protein</fullName>
            <ecNumber evidence="11">3.6.3.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Mal33_26630</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.6.3.-" evidence="11"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="116"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="203"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="306"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="340"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="10">
        <location>
            <begin position="65"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="399"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="24"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="433"/>
            <end position="440"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QDV56665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="651" mass="72579" checksum="AC9AB23A1218C1D6" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUA3</accession>
    <name>A0A518IUA3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_26730</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021793262" evidence="1">
        <location>
            <begin position="26"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="115" mass="12379" checksum="6061ED9B22910BD2" modified="2019-10-16" version="1" precursor="true">MRLWLGLVIAVFTLVLANVSPGSGAGETQTKPEASRPALVAGAGELLGFVNPQANDGQQITIVNATRGTMLVYHIDGPTGQITLKSSRRLTWDFSLDEYNATAPLPTEIRQMVER</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUB8</accession>
    <name>A0A518IUB8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_26660</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021995056" evidence="1">
        <location>
            <begin position="24"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="102" mass="10374" checksum="9DA8919D6869C995" modified="2019-10-16" version="1" precursor="true">MMGRCVFGVLLTLAMIGCGSGTAPVKVQPTVTPAAQTVKATLEQVAESGELGSGAEELQKALEEMKASDPAKADALLSDFESLKNSSGASAKSKAKAMLGKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUE5</accession>
    <name>A0A518IUE5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Phenylacetate-coenzyme A ligase</fullName>
            <ecNumber evidence="4">6.2.1.30</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">paaK</name>
        <name evidence="4" type="ORF">Mal33_27000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="6.2.1.30" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047475">
        <property type="term" value="F:phenylacetate-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028154">
        <property type="entry name" value="AMP-dep_Lig_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14535">
        <property type="entry name" value="AMP-binding_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding" evidence="2">
        <location>
            <begin position="116"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding_C_2" evidence="3">
        <location>
            <begin position="359"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV56702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="443" mass="49015" checksum="E96DA76F572B78FA" modified="2019-10-16" version="1">MPHRANATSLFDAIFICIVAIMLTYDATDRLSFTRLRRDLLEAMQIERFNRLIEATLPQNSFHDDRLGDIQFPLQALGELRHLPTLAKADLIAAGDTFPPRFHTFDASRYIRLHRTSGTTGRPLPLLDTADDWQWWIDTWQFVLDAADVTADDRAFMAFSFGPFIGFWSANDALAARGAMVIPGGGLSTAARLTLLQDSDATILCCTPTYALHMADVARAESIPIESSAIRCVIVAGEPGGSIPEVRQRIEAAWGAKVIDHSGATEIGPWGFGTADGTSLHVIETEFIAEFLLEDGTPAAEGQLSELVLTNLGRIGAPIIRYRTGDLVRPRWDHRDECRFVRLEGGVLGRADDMVVVRGVNVFPSSIERVIRSIPELGEFRILLSKQGEMDQVSVEVEDPQNDPQRIGKQFETAIGLRIAIKIVPEGSLPRFEAKARRVVDNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUN9</accession>
    <name>A0A518IUN9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glutamate synthase [NADPH] small chain</fullName>
            <ecNumber evidence="7">1.4.1.13</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">gltB_1</name>
        <name evidence="7" type="ORF">Mal33_28040</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis.</text>
    </comment>
    <dbReference type="EC" id="1.4.1.13" evidence="7"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00089"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004355">
        <property type="term" value="F:glutamate synthase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006537">
        <property type="term" value="P:glutamate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028261">
        <property type="entry name" value="DPD_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006005">
        <property type="entry name" value="Glut_synth_ssu1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14691">
        <property type="entry name" value="Fer4_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01317">
        <property type="entry name" value="GOGAT_sm_gam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3" id="KW-0314">Glutamate biosynthesis</keyword>
    <keyword evidence="2 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fer4_20" evidence="6">
        <location>
            <begin position="24"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="Pyr_redox_2" evidence="5">
        <location>
            <begin position="146"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF14691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV56804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="499" mass="54908" checksum="9035BBDCD09EF3F3" modified="2019-10-16" version="1">MGKPTGFKEFDRKKVPWRLPVVRINDYQEIYTEPKEELLREQGARCMDCGVPFCQSSSGCPIDNLIPEWNDLVYNGRWEDAIQRLHKTNNFPEFTGRVCPAPCEGSCVLGITNPPVTIKNIENAIVDRAWQEGWIKPEPPNARTGKKVAIIGSGPAGLAAADQLNRAGHLVTVFERASRIGGLLMYGIPNMKLDKNQVARRVEKMTTEGVTFKTNVNVGVDIDPKDLQKDFDAVLLSTGATKPRDLPIPGRDLNGVHFAMDYLTGNTKKVLDKTDTAEFINSEGKDVIVIGGGDTGTDCIGTSIRHGCKSMVNFELLPQPPEERADDNPWPEWPRVFRTDYGHEEAAAKFGKDPRTYCILSKEFIDDGQGNLSGIRTVGVEWTKKSDGGWAMSEIEGSEKVWPAQRVYLAMGFLGPEQYLVESMGFETDARSNYKAEHGKFTTSIEGVFAAGDCRRGQSLVVWAINEGRGAARAIDIYLQGSSVLPAPGTTMGTELSAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUS0</accession>
    <name>A0A518IUS0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Nickel and cobalt resistance protein CnrA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">cnrA_2</name>
        <name evidence="4" type="ORF">Mal33_28370</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2090.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004763">
        <property type="entry name" value="CzcA/CusA/SilA/NccA/HelA/CnrA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82714">
        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00914">
        <property type="entry name" value="2A0601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="428"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="457"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="543"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="574"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="634"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="979"/>
            <end position="999"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1006"/>
            <end position="1026"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1032"/>
            <end position="1059"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1080"/>
            <end position="1102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1108"/>
            <end position="1130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV56836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1162" mass="127278" checksum="31459C7675FE8597" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IV39</accession>
    <name>A0A518IV39_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_29260</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011453">
        <property type="entry name" value="DUF1559"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07596">
        <property type="entry name" value="SBP_bac_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="374" mass="40365" checksum="69F80D5F437B5E49" modified="2019-10-16" version="1">MWGGRSNGSFDSTIHFSLEILSLQKFSRRNGFTLVELLVVIAIIGILVGLLLPAVQAAREAARRMQCSNNLKQLGISLHNYHDTYKSFVPRKQGTGTCGSPRDNCNRLSGFIGLLPFMEQKPMYDQIMAGDGTRPPGGPEGWASWSVWDQAPEGLRCPSGAYSGTPDSTNNYMFSVGDQIDNNRDRTDVRGVFAYRRGARFADITDGTSNTIAMSEHQRGNFSRGTNSQPRIQMSIIGSVDPRTNPGACLQTHTNGIYNNVAEVKSRFGTRWTDGQTERVGFTTVIPPNGPSCHEGTDVNADAAHSVISPSSYHPGGVMSVFCDGSVRFISDTIDTGSLSSVAAWRGTGYDSGTSPFGVWGAMGSKNGGEIVTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IV60</accession>
    <name>A0A518IV60_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Coenzyme A biosynthesis bifunctional protein CoaBC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">coaBC_1</name>
        <name evidence="2" type="ORF">Mal33_29750</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035929">
        <property type="entry name" value="CoaB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007085">
        <property type="entry name" value="DNA/pantothenate-metab_flavo_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04127">
        <property type="entry name" value="DFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102645">
        <property type="entry name" value="SSF102645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DFP" evidence="1">
        <location>
            <begin position="3"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="209" mass="22573" checksum="015F638410971D19" modified="2019-10-16" version="1">MAKILITSGPTRQYLDPVRYLTNASSGRMGAALAQAALDLGHQVVVVSGPVSVTYPAAAEVIDVLTTQEMLEVAHGEFQQCDGAIGAAAPCDYQPQQVETEKISKTGKPLQLNLVETPDVVATLGERKRSDQWVVGFALETQDRHFRAIVKLEKKHCDLMVSNGPEAIDSAENQVDLIDAEGQLLEQISGSKLDVARGILKVIDARLIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IV93</accession>
    <name>A0A518IV93_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Acetyltransf_6 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_30110</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038740">
        <property type="entry name" value="BioF2-like_GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13480">
        <property type="entry name" value="Acetyltransf_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acetyltransf_6" evidence="1">
        <location>
            <begin position="216"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="406" mass="46059" checksum="9D985F70313E3898" modified="2019-10-16" version="1">MIQKLSTSLLQPAASKPKLGQKHYRVAEVDLPQLDFRGRIVRNLDELESIADRWQRLMETAIHPNLFFDPDFLIPALRHLNDRDAAVLVIEAPRRMHPEGDPVLCGLMPLVAKRIYGLPLSGREIWKHDQCFDCTPLLRRDCAAEAWRFALEYLATEQGVQLLSMNTVSGQDQFANLITDHFYAASTTVFHRDAFTRACFQPAPDAETYLNAQVSKSTRKGTQRLSRKLAQQGELTTRCADQDDHAAWIEEYIALEATGWKGRQGTAFDSSEGSREFFRESATRMLSKHKMQILKISLDDRPISMMCDLVTSDRGAHFKTTFDETLHEYSPGLIAELENIPIMHDRGLEIVDSCADPDHSMINRVWPDRIRFQSLVVALGGKLSQLAVASLPMLQLVRHSFKKKGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVE8</accession>
    <name>A0A518IVE8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Adenosylcobinamide kinase</fullName>
            <ecNumber evidence="8">2.7.1.156</ecNumber>
            <ecNumber evidence="9">2.7.7.62</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Adenosylcobinamide-phosphate guanylyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="primary">cobU</name>
        <name evidence="18" type="ORF">Mal33_30590</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>adenosylcob(III)inamide + ATP = adenosylcob(III)inamide phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15769"/>
            <dbReference type="ChEBI" id="CHEBI:2480"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58502"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.156"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>adenosylcob(III)inamide + GTP = adenosylcob(III)inamide phosphate + GDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15765"/>
            <dbReference type="ChEBI" id="CHEBI:2480"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="ChEBI" id="CHEBI:58502"/>
            <dbReference type="EC" id="2.7.1.156"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>adenosylcob(III)inamide phosphate + GTP + H(+) = adenosylcob(III)inamide-GDP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22712"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:58502"/>
            <dbReference type="ChEBI" id="CHEBI:60487"/>
            <dbReference type="EC" id="2.7.7.62"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6">Cofactor biosynthesis; adenosylcobalamin biosynthesis; adenosylcobalamin from cob(II)yrinate a,c-diamide: step 5/7.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Cofactor biosynthesis; adenosylcobalamin biosynthesis; adenosylcobalamin from cob(II)yrinate a,c-diamide: step 6/7.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the CobU/CobP family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.156" evidence="8"/>
    <dbReference type="EC" id="2.7.7.62" evidence="9"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00148">
        <property type="reaction ID" value="UER00236"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036429">
        <property type="term" value="F:adenosylcobinamide kinase (ATP-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036428">
        <property type="term" value="F:adenosylcobinamide kinase (GTP-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
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        <property type="term" value="P:cobalamin biosynthetic process"/>
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    </dbReference>
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        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003203">
        <property type="entry name" value="Cobinamide_kinase/P_G-Trfase"/>
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        <property type="entry name" value="P-loop_NTPase"/>
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    <dbReference type="PANTHER" id="PTHR34848">
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="17" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="12" id="KW-0418">Kinase</keyword>
    <keyword evidence="11 17" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 18" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="GMP-histidine intermediate" evidence="16">
        <location>
            <position position="70"/>
        </location>
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        <location>
            <begin position="22"/>
            <end position="29"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
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        <location>
            <begin position="48"/>
            <end position="50"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
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        <location>
            <begin position="71"/>
            <end position="74"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
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        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000312"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00000711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00003889"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00004692"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00005159"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00007490"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00012016"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00012523"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00029570"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00030571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR006135-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR006135-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="QDV57058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="222" mass="23432" checksum="A18036495BB022D6" modified="2019-10-16" version="1" precursor="true">MSQAVEQDQSSGPAGSVTLVLGGVRSGKSRFAQDLAGQIGGDDVLFVATAQASFQDQPADEEMTRRIDHHRRSRPSAWSTLEQPRDVGQAILQTSPLASVVLVDCLTLLVSNVICDGDHSKSGLHDLEARVIAEVDALIQVAAQRPTHLIIVSGEVGCGIVPEHPLGRTFRDLLGLANQRLAASDATTYWMVAGLAINATAIASSTEQAAQQIQHLANGAPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVF4</accession>
    <name>A0A518IVF4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RES domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_30660</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
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        <property type="entry name" value="RES_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08808">
        <property type="entry name" value="RES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00953">
        <property type="entry name" value="RES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RES" evidence="1">
        <location>
            <begin position="49"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="199" mass="21802" checksum="BEB3964B7647D70D" modified="2019-10-16" version="1">MRKKKVIPTDPPEVIKLFKAIAGLYPDAGGFDDVIVRSIGMKYASKNNFYSGAGAAKVGGRWNPKGLEAIYASLDVETATLEAYQDFIYRGFPMTAITPRVTAAAKVELSKTLDLTDSKIRKTLGFDQKTLIQEDWRALQRVGEESWTQAIGRGSCIAKFEALIVASARKIDGKNIVIFPQNLSNTSKIDILGSDQLPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVI1</accession>
    <name>A0A518IVI1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 11">Anthranilate synthase component 1</fullName>
            <ecNumber evidence="5 11">4.1.3.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11 14" type="primary">trpE</name>
        <name evidence="14" type="ORF">Mal33_30900</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>chorismate + L-glutamine = anthranilate + H(+) + L-glutamate + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:21732"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16567"/>
            <dbReference type="ChEBI" id="CHEBI:29748"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="EC" id="4.1.3.27"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 1/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 11">Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the anthranilate synthase component I family.</text>
    </comment>
    <dbReference type="EC" id="4.1.3.27" evidence="5 11"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004049">
        <property type="term" value="F:anthranilate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000162">
        <property type="term" value="P:tryptophan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005801">
        <property type="entry name" value="ADC_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019999">
        <property type="entry name" value="Anth_synth_I-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006805">
        <property type="entry name" value="Anth_synth_I_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005256">
        <property type="entry name" value="Anth_synth_I_PabB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015890">
        <property type="entry name" value="Chorismate_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11236">
        <property type="entry name" value="PTHR11236"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04715">
        <property type="entry name" value="Anth_synt_I_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00425">
        <property type="entry name" value="Chorismate_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00095">
        <property type="entry name" value="ANTSNTHASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56322">
        <property type="entry name" value="SSF56322"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00564">
        <property type="entry name" value="trpE_most"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9 11" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="10 11 14" id="KW-0456">Lyase</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="domain" description="Anth_synt_I_N" evidence="13">
        <location>
            <begin position="28"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="Chorismate_bind" evidence="12">
        <location>
            <begin position="226"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00020653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU364045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF04715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="QDV57089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="501" mass="55320" checksum="9A26401B292B6B87" modified="2019-10-16" version="1">MHTPNEDQFTHLASTHDLVPVSRRLLSDSLTPVSAFRLLDNGRSACLFESVIGGEKVGRFSFLAVDPIMRFCAHGQSVSITRGDACETKTCDDPLDEFRGHLAGVTFADTGDLPPFVGGAIGYAGYDVVRYVENLPNAPEDDRQLPDLDFGFYHTLVVFDNVTKTMTIVAVARPADFDSPAEAYRDAKQRIDETVAQLSRPVPHLETADVEQSHDEQLDISSNFTREGFADAVEKCREYIRAGDIFQVVPSQRFAVDTSVDPFEIYRSLRVVNPSPFMFYMRTPECTLIGCSPEIMTRVVDGVVTVRPLAGTRRRGATEQEDLALEEELLSDPKERAEHVMLVDLGRNDIGRIAKFGTVELTEVMVVERYSHVMHISSEVRGELRDGLDAFDALKACLPAGTVSGAPKVRAMEVIDELEPHRRGPYGGAVGYIDYRGNMDTCIALRTMVVQNDKVYVQAGCGVVADSNPDAEYEETVNKAKGMVRAISLTLSRLNANKRDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVS3</accession>
    <name>A0A518IVS3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">VWFA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_31930</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024163">
        <property type="entry name" value="Aerotolerance_reg_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07584">
        <property type="entry name" value="BatA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13519">
        <property type="entry name" value="VWA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="630"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="2">
        <location>
            <begin position="93"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="660" mass="72407" checksum="562C248C37B1F3D7" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVX4</accession>
    <name>A0A518IVX4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">GHL10 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_32400</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003790">
        <property type="entry name" value="GHL10"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02638">
        <property type="entry name" value="GHL10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021792100" description="GHL10 domain-containing protein" evidence="3">
        <location>
            <begin position="25"/>
            <end position="1362"/>
        </location>
    </feature>
    <feature type="domain" description="GHL10" evidence="4">
        <location>
            <begin position="489"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1206"/>
            <end position="1258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1275"/>
            <end position="1362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1238"/>
            <end position="1258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1332"/>
            <end position="1349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV57236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1362" mass="148757" checksum="752D983EBCFF6DA2" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IW36</accession>
    <name>A0A518IW36_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Dihydroorotase</fullName>
            <ecNumber evidence="7">3.5.2.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">pyrC_2</name>
        <name evidence="7" type="ORF">Mal33_33020</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.5.2.3" evidence="7"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004151">
        <property type="term" value="F:dihydroorotase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002195">
        <property type="entry name" value="Dihydroorotase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00483">
        <property type="entry name" value="DIHYDROOROTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="6">
        <location>
            <begin position="49"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV57298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="447" mass="49147" checksum="7F8D08A97727EE79" modified="2019-10-16" version="1">MKTLIKNATVVFPDQIGKVSVLIDDGRIVVDPSPATVADETIDASGLHLLPGAIDDQVHFRQPGLEHKEDLAHASRACAAGGVTTFLEMPNTNPTTTTRERLREKNALGATHSAVNYGFYMGATTSNLDELKPSGETPGIKIFIGSSTGNMLVDEQAVLEQIFAETEMPICAHCEDETTVRANAERYAGSDDITDHSRIRSPEAAYIATRRAVDLSVRHQHRFHVLHVSTAAELELITPARPYVTAEVCPHHLFFNVDDYARLGSLIQMNPSIKSADDNRQLWQALLDGAIQVIATDHAPHTLAEKQQPYPKSPSGLPAVENSLPLLLNQVAQGKCDLQQVVHWMCDAPARVWGIVGKGRIADGYDADLVLVDLEQQKTIRNEEQQTKCRWSPWDGETLTGWPVTTWVGGRRVFDRGRFDASIRGTLPLFDHQRGGYWATEQGVGLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IW77</accession>
    <name>A0A518IW77_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Alcohol dehydrogenase [acceptor]</fullName>
            <ecNumber evidence="6">1.1.99.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">alkJ</name>
        <name evidence="6" type="ORF">Mal33_32990</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.99.-" evidence="6"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="PTHR11552"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00623">
        <property type="entry name" value="GMC_OXRED_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GMC_OxRdtase_N" evidence="4">
        <location>
            <begin position="84"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="domain" description="GMC_OxRdtase_N" evidence="5">
        <location>
            <begin position="240"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="205"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS00623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV57295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="520" mass="55942" checksum="9E4FE14ACF20A13B" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWE6</accession>
    <name>A0A518IWE6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_34130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="1">
        <location>
            <begin position="14"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="133" mass="14326" checksum="DE8B34A4530ABFA2" modified="2019-10-16" version="1">MFSVLLTALLSVVASEQAPSPDYATAYRSAQEEGKPLMVVVGADWCPACVNLKQNTIASLKQAGDLEGVEMAIVNRDTQPGLAGKLMRGPMMPQIIVFSKGNAGSWTRTQLTGFQTRDSLRSLIKRAVRNKGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IX08</accession>
    <name>A0A518IX08_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_36290</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="154" mass="15745" checksum="315EF2424721FD1F" modified="2019-10-16" version="1">MKLVRNCGAVVATLCVGMLVVGCGSTEQLLDVVPASGKVTVDGKPVEGISVSLLPQDGVPGRGGYGVTDATGAFTVTSVEGQDGVAEGKYKVVFQKLTQPDGSPIPPGSNAADVGAVNSLPAAYNDPDLSTMFAIIKADGTSEMEFDLNSKRKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IX41</accession>
    <name>A0A518IX41_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Inner membrane protein YgaP</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ygaP</name>
        <name evidence="3" type="ORF">Mal33_36580</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021309">
        <property type="entry name" value="DUF2892"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11127">
        <property type="entry name" value="DUF2892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="117"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="142"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodanese" evidence="2">
        <location>
            <begin position="14"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="182" mass="19107" checksum="0CB1C9B7A1C671A6" modified="2019-10-16" version="1">MKSIEVTQLSELQKNGDVELIDVRMPSEFRSVHAAGARNVPLDSLDPSSVFADRNGSKDQPLYVICQGGNRSTKACQKFVDAGFENIVNVEGGTTAWDKAGLPVVRGKQTMPLMQQVQLTAGSLVLLGAVLGYFVHPYFIGLSAFVGAGLMFAGATGTCGMASMLGKMPWNQCAGGGGSCSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IX66</accession>
    <name>A0A518IX66_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_36930</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021893374" evidence="2">
        <location>
            <begin position="25"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="124"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="636" mass="69823" checksum="F3E6DB798A39E7C2" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IX84</accession>
    <name>A0A518IX84_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Demethylmenaquinone methyltransferase</fullName>
            <ecNumber evidence="4">2.1.1.163</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ubiE_3</name>
        <name evidence="4" type="synonym">menG</name>
        <name evidence="5" type="ORF">Mal33_37080</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a 2-demethylmenaquinol + S-adenosyl-L-methionine = a menaquinol + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42640"/>
            <dbReference type="Rhea" id="RHEA-COMP:9539"/>
            <dbReference type="Rhea" id="RHEA-COMP:9563"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18151"/>
            <dbReference type="ChEBI" id="CHEBI:55437"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="EC" id="2.1.1.163"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Quinol/quinone metabolism; menaquinone biosynthesis; menaquinol from 1,4-dihydroxy-2-naphthoate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.163" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00079">
        <property type="reaction ID" value="UER00169"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043770">
        <property type="term" value="F:demethylmenaquinone methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102094">
        <property type="term" value="F:S-adenosylmethionine:2-demethylmenaquinol methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102955">
        <property type="term" value="F:S-adenosylmethionine:2-demethylmenaquinol-7 methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102027">
        <property type="term" value="F:S-adenosylmethionine:2-demethylquinol-8 methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009234">
        <property type="term" value="P:menaquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01813">
        <property type="entry name" value="MenG_UbiE_methyltr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004033">
        <property type="entry name" value="UbiE/COQ5_MeTrFase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023576">
        <property type="entry name" value="UbiE/COQ5_MeTrFase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01209">
        <property type="entry name" value="Ubie_methyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01934">
        <property type="entry name" value="MenG_MenH_UbiE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51608">
        <property type="entry name" value="SAM_MT_UBIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01183">
        <property type="entry name" value="UBIE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01184">
        <property type="entry name" value="UBIE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0474">Menaquinone biosynthesis</keyword>
    <keyword evidence="1 4 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4 5" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="4">
        <location>
            <begin position="116"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="68"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="89"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV57695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="244" mass="27198" checksum="E2C4FD714C1C4DF9" modified="2019-10-16" version="1">MATVDATNTKELDKSNARVREMFRQIAPRYDLMNHLLSLNIDKRWRNQTVSRLRIEGNAPILDVCTGTGDLALAISRRAGAETPVVGSDFCHAMLAIGDQKRKQQPEANVNFLEADAQHLPFDDNQFQVVTVAFGLRNVADTDRGLQEMVRVCRPGGQVVVLEFSQPTAPGLKQAYQFYFKHALPRIGQMLARNDKSAYQYLPESVGSFPCGQALADRMQQNGLHDVKFTPLTFGVATIYEGIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXB8</accession>
    <name>A0A518IXB8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_37380</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="110" mass="12230" checksum="054F4282873510CD" modified="2019-10-16" version="1">MTCHELAKRLLALQPELTPQSVAQLALLILNGVSDADELADDQTLLRHWHSASFRLQAAADQHAAMTDELEQLAGDGPVKFEPDQIWTLLRAIKVQSQLLELYTDEPAMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXR0</accession>
    <name>A0A518IXR0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Signal transduction histidine-protein kinase BarA</fullName>
            <ecNumber evidence="10">2.7.13.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">barA_11</name>
        <name evidence="10" type="ORF">Mal33_38890</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="10"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00088">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036641">
        <property type="entry name" value="HPT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008207">
        <property type="entry name" value="Sig_transdc_His_kin_Hpt_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01627">
        <property type="entry name" value="Hpt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
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        </source>
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</entry>
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
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                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="1 2">Mal33</strain>
        </source>
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            <dbReference type="EMBL" id="QDV57971.1"/>
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            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
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</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
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    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
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                <person name="Kaster A.-K."/>
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                <person name="Rohde M."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 4">Mal33</strain>
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        <source>
            <dbReference type="EMBL" id="QDV57999.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="585" mass="65206" checksum="A15372692052AD9B" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IY40</accession>
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        <submittedName>
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        <name evidence="9" type="primary">fadE</name>
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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                <person name="Pinto D."/>
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                <person name="Peeters S.H."/>
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                <person name="Oberbeckmann S."/>
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                <person name="Jeske O."/>
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                <person name="Luecker S."/>
                <person name="Lage O.M."/>
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                <person name="Bruemmer F."/>
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                <person name="Overmann J."/>
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                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
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            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
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    </comment>
    <comment type="similarity">
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        <property type="protein sequence ID" value="QDV58009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="component" value="Chromosome"/>
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        <property type="term" value="F:flavin adenine dinucleotide binding"/>
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        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="AcylCo_DH-like_C"/>
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        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
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        <property type="entry name" value="AcylCoA_DH/ox_N"/>
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        <location>
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        </location>
    </feature>
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    </feature>
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        </location>
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    <evidence type="ECO:0000256" key="1">
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        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
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        <source>
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        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV58009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="588" mass="64792" checksum="3AA68F42D76B2968" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IY73</accession>
    <name>A0A518IY73_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_40440</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="59"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="146" mass="16305" checksum="DD36F1C45DA119AB" modified="2019-10-16" version="1">MKTPENVEALWDDLDNMQSQMRIGITALPPSKAKDLMNRLMEVAQPLVGKMRTAYPEAIDAFEKQHAELEEKLDRARQNIAKAKENLANVPPVEEIRKNLVPLAVALPSGLSLQFADEMRTRYVPPAPDLTLDDGPGAAWQDWSIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IY90</accession>
    <name>A0A518IY90_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_40730</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="217"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="282"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="314" mass="33506" checksum="70880BDD57E70D85" modified="2019-10-16" version="1">MSARLESRCRVATLFWALAISLLIGCGTTKSRTATDQLLLSDAVDRSVSAIDFRPLTGKKVYLDTTYLSAVKGTLFVNSDYIISSLRQQIIAAGCLLEEDRKTAELIIEARVGTLGADGHMVSYGIPASNALATAASLVAEAAPVPTIPEISFAKRESNEASAKIAAFAYDRETRQAVWQSGISRSESNSRETWILGAGPFESGSVRENTRLAGRELPFDGTEDSLQSSDSQPVRPPVDLNMQARFEDGYPIVPGAPPQPDLMNESSEAVVLDASQGGELKTVSFEEAAKHAEAANASDAAKPGDGPKDKPEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYI2</accession>
    <name>A0A518IYI2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Cyclic dehypoxanthine futalosine synthase</fullName>
            <shortName evidence="6">Cyclic DHFL synthase</shortName>
            <ecNumber evidence="6">1.21.98.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Dehypoxanthine futalosine cyclase</fullName>
            <shortName evidence="6">DHFL cyclase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Menaquinone biosynthetic enzyme MqnC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">mqnE_2</name>
        <name evidence="6" type="synonym">mqnC</name>
        <name evidence="8" type="ORF">Mal33_41720</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>dehypoxanthine futalosine + S-adenosyl-L-methionine = 5'-deoxyadenosine + cyclic dehypoxanthinylfutalosinate + H(+) + L-methionine</text>
            <dbReference type="Rhea" id="RHEA:33083"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:58864"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:64270"/>
            <dbReference type="EC" id="1.21.98.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="6">Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Quinol/quinone metabolism; menaquinone biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the radical SAM superfamily. MqnC family.</text>
    </comment>
    <dbReference type="EC" id="1.21.98.1" evidence="6"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00079"/>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046992">
        <property type="term" value="F:oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016765">
        <property type="term" value="F:transferase activity, transferring alkyl or aryl (other than methyl) groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009234">
        <property type="term" value="P:menaquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00992">
        <property type="entry name" value="MqnC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045567">
        <property type="entry name" value="CofH/MnqC-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022431">
        <property type="entry name" value="Cyclic_DHFL_synthase_mqnC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034405">
        <property type="entry name" value="F420"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020050">
        <property type="entry name" value="FO_synthase_su2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43076">
        <property type="entry name" value="PTHR43076"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19288">
        <property type="entry name" value="CofH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00343">
        <property type="entry name" value="aminofutalosine_synthase_(mqnE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03699">
        <property type="entry name" value="menaquin_MqnC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00423">
        <property type="entry name" value="TIGR00423"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4 6" id="KW-0408">Iron</keyword>
    <keyword evidence="5 6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="6" id="KW-0474">Menaquinone biosynthesis</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Radical SAM core" evidence="7">
        <location>
            <begin position="62"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="76"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV58155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="392" mass="43837" checksum="603CA5191F1B6594" modified="2019-10-16" version="1">MSSGSTTQPQTNTQAILDKAVAGDRISFEEGLHLLQTDDLSLAKLGAAADAITRRLHPEPYRTYNIDRNINYTNVCTAVCDFCAFYRGPKSDEGYVLPREELLQKVAETVQLGGNQILMQGGLHPKYKLDWYEELLQDIVTNYPSINVHGFSPPEIHHFTKVNNLSLREVLSRLKAAGLGSLPGGGAEILVDRVRSEITRGKVMTDDWLNVMRVWHELGGISSATMMFGHVETLAERIEHLDRLRQVQDETGGFTAFICWTFQPEHTEMAHIAPAGSFEYLKMQAVARLFLDNIPNIQSSWVTQGSKIGQLALLYGANDMGSLMIEENVVAEAGTVHYQSLRRIRESIEEIGYQARQRDVHYNLVDPELERRAIEANGDLGPKELVQLSASQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYU7</accession>
    <name>A0A518IYU7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">UDP-2,3-diacylglucosamine hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_42830</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallophosphoesterase superfamily. YfcE family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024654">
        <property type="entry name" value="Calcineurin-like_PHP_lpxH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043461">
        <property type="entry name" value="LpxH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34990">
        <property type="entry name" value="PTHR34990"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12850">
        <property type="entry name" value="Metallophos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos_2" evidence="2">
        <location>
            <begin position="26"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="280" mass="32172" checksum="A43AA14140E32490" modified="2019-10-16" version="1">MTSTQQTTVSSRNASSATWELSDARTLFLSDIHLGSRFCQVEPLLQLLERCWPQKIYLVGDVVDNRRMSRKLRWTPAYNRLVARLFDLGVSGTEIYYTPGNHDTFLRSFVEDYRLVQIRDSFIHQCADGKRLAVLHGDQFDMVESQMKWLSFVGSFAYEGLLAIDRSINAVLRLFGARGIPISRSLKLWAKSCVQKKSGFHQQLCDFARDQECEGVVCGHIHKPEITQIEEITYLNTGDWIEHCSAIVEWPDGRLQLIDSQNLNKTRPCEPTFHRLRSNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYV1</accession>
    <name>A0A518IYV1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mannosylfructose-phosphate phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.79</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">mfppA</name>
        <name evidence="2" type="ORF">Mal33_42780</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.3.79" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006379">
        <property type="entry name" value="HAD-SF_hydro_IIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006380">
        <property type="entry name" value="SPP_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05116">
        <property type="entry name" value="S6PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01484">
        <property type="entry name" value="HAD-SF-IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S6PP" evidence="1">
        <location>
            <begin position="11"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="274" mass="29432" checksum="8B940F8A021D76DB" modified="2019-10-16" version="1">MQETKPQLTPPNVLATDLDGTLIPLNNDATNRRDLARLRSHFESSDCTLVFVTGRHLQSAQQAIADFDLPVPDWIICDVGTTICKSDGSGNFLSVKGYEARLAQLTEGLSQEAVRTALTPLSGLRLQEPEKQGRFKLSYYADQSELASLTQQVADRIATLPYSMISSVDPFNGDGLIDLLPQGASKAYALQWWATETGRSATDLVFAGDSGNDLAALTAGYRTIVVGNADASVVDAARLAHHKAGWTDRLHLAKACATSGVLEGCRFHGLIADA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYX2</accession>
    <name>A0A518IYX2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Nicotinate-nucleotide diphosphorylase (carboxylating)</fullName>
            <ecNumber evidence="4">2.4.2.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Quinolinate phosphoribosyltransferase [decarboxylating]</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">nadC</name>
        <name evidence="13" type="ORF">Mal33_43020</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the catabolism of quinolinic acid (QA).</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from quinolinate: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the NadC/ModD family.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.19" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00331"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004514">
        <property type="term" value="F:nicotinate-nucleotide diphosphorylase (carboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01572">
        <property type="entry name" value="QPRTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004393">
        <property type="entry name" value="NadC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027277">
        <property type="entry name" value="NadC/ModD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036068">
        <property type="entry name" value="Nicotinate_pribotase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037128">
        <property type="entry name" value="Quinolinate_PRibosylTase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002638">
        <property type="entry name" value="Quinolinate_PRibosylTrfase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022412">
        <property type="entry name" value="Quinolinate_PRibosylTrfase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32179">
        <property type="entry name" value="PTHR32179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01729">
        <property type="entry name" value="QRPTase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02749">
        <property type="entry name" value="QRPTase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006250">
        <property type="entry name" value="NadC_ModD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51690">
        <property type="entry name" value="SSF51690"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00078">
        <property type="entry name" value="nadC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9 13" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="QRPTase_N" evidence="12">
        <location>
            <begin position="34"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="QRPTase_C" evidence="11">
        <location>
            <begin position="122"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="143"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="266"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="287"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="219"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="240"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00033102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR006250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR006250-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="QDV58284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="308" mass="34052" checksum="398A1B5C90E2A90E" modified="2019-10-16" version="1">MAVEYQQIRVDAPLEDDFRQLIRLAVREDFDRQIDWTTVSLVPEDRIGKCQVAVREAGIAAGLVTLPWIIDEMNLELRIETLVEDGARVAAGQIVAQIEGSARDILSSERIVLNTLCRMFGIATFTDRFVQQISGTKARLYDTRKTTLGWRRMDKYAVRCGGGTNHRLGLFDAFLIKDNHLALAGPGEAIPPSEAVAKAKSWAGGESAGMKAPQIVEVEVDTLEQFQDVLPAGPDIILLDNFSLDDLRQAVAIRNEKSPQIELEASGNVKLETIREIAETGVDRISSGALTHAARWLDLGLDWTHDFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYY2</accession>
    <name>A0A518IYY2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Outer membrane biogenesis protein BamB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_43120</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018391">
        <property type="entry name" value="PQQ_beta_propeller_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002372">
        <property type="entry name" value="PQQ_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13360">
        <property type="entry name" value="PQQ_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00564">
        <property type="entry name" value="PQQ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022230546" evidence="1">
        <location>
            <begin position="20"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="413" mass="44991" checksum="E6C3D09F720B963B" modified="2019-10-16" version="1" precursor="true">MRCCLLLLLVALQASTVLASDWLAWRGPTADNHARQGESVPTSWSETENVLWKTPVPGRGHATPIIVGDRIYLATADKTKDVQSVVAFDRQTGAEEGVIVVHDGGVDVKIHSKNTYASPTIASDGKQLYTVFVNNKAVWASAISLGGKILWQQRVGEFDPKKYPFGYGASPVVYRDVLIVANEYDGPDSGLYAFDTATGKSRWQAERPQHSSFSSPIVAKVADRDQLLISGLRQIASFDPVTGRSLWQADGTTDATCGTVVWDGDLVFASGGFPDSGTFAVRADGSGEVVWQNRVKCYEQSMLVVDGYLYAVADSGVAYCWRASDGQEMWKQRLKGPVSASPLAVGDTIMASNERGTTYVFKANPERFEELAENQWGNSSFASPVVVDDRIYLRHAKGDGADRQEFLVCIGEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ19</accession>
    <name>A0A518IZ19_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase</fullName>
            <ecNumber evidence="3">2.4.2.53</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">arnC_3</name>
        <name evidence="3" type="ORF">Mal33_43480</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.4.2.53" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0099621">
        <property type="term" value="F:undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="241"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="286"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_2-like" evidence="2">
        <location>
            <begin position="15"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="333" mass="37304" checksum="3F2E11210D824645" modified="2019-10-16" version="1">MTQPTPPAAAAESISFVIPVCNEEDSLDELHAAISEVVQENGYDAEMIFIDDGSTDASWQKVQGLAARDPRVQGLRFRTNFGKAAGLAAGFDAARGTFIITMDGDLQDDPKEIPRFLQRLHEGFDVVSGWKQVRHDPWHKVLPSRVFNWMVGALTGVRIHDHNCGFKAYRREVFDEVKLYGELHRFVPVLAAAKGWRVSEIAVEHHARKYGHSKYGVRRLVKGFLDLATVYFLTGYSQRPLHLMGTTGILSTLLGLAGLVWLSISWVFTRLNDLPEDDMHLHTRAIFYFCIMAFLVGTQLMIAGLLAELLTATSRREVQPYSIAERTEASTDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ76</accession>
    <name>A0A518IZ76_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HTH-type transcriptional repressor YtrA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ytrA</name>
        <name evidence="2" type="ORF">Mal33_44040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="1">
        <location>
            <begin position="10"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="130" mass="15066" checksum="88502A2B6DB0D281" modified="2019-10-16" version="1">MQLHISTDGVPIFQQIVDQIQYRIVSGQLAAGDELPTIRGLAESLRVNPNTVARAYRELEHEGLVEKRRTTGTFVAEQIERRTLNQRRDLLKPHLQRLIIQSRQLGFSIDDVIEQLKKRDDQIPRDENRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZC1</accession>
    <name>A0A518IZC1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_44590</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001842">
        <property type="entry name" value="Peptidase_M36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02128">
        <property type="entry name" value="Peptidase_M36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="502" mass="54100" checksum="91974574E993914A" modified="2019-10-16" version="1">MPINFIPNDPLSQAFAPLRTIDPLPERPADRAGFRFSGVQGEGEHSVGTKEFLFWQCREAALRSIETWEALNGPLKRWQGNKKTLLLRQDAGDDLNAYYDRSSLSFFHHTSGQKTTYSGASTDVVAHEAGHAFLDAIRPQLFSVNFTETGAFHEAFGDLVAILTALMDPLTRETLLAESPDLRTANYVEATAEDLSDGIRREYGASHAASKPRRALNEFVWQHPILLPHSAPPDELSSEIHSFGRVVSGCVYDTLANIFNSRPNRDEQSLLEAAQTTGRLLIGAAKIAPSESRYFRAVGRAMILVDSELNGGANHLSIRDAFAAHNIPLGSSAMLAPVSLLAGGAPSMSGRSQKISIPKSVTTDLAKRLGVASTAKFAVQSFQMAGETIAEAIHEHEVPLGGLDRRLKGVVAFAPASVLVGEVSARAAVLGGLPDVQGAADEVVQFVETLLDNDRVKYEDSNAAESGAPGRFKTHEIQSVRGKRVLTRIAFDCFGGCGCSHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZK9</accession>
    <name>A0A518IZK9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_45500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012451">
        <property type="entry name" value="DUF1656"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07869">
        <property type="entry name" value="DUF1656"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="96" mass="10822" checksum="6FF72A40005EC445" modified="2019-10-16" version="1">MHCKAMPWRERFDSWNIVRYGVAVIVLVKTASEISLGWVYITPALVAVTLGFLAAYGVTWLLNATRLARFFWNPGLTFVAFVVLFTSLIGLLFIPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZP3</accession>
    <name>A0A518IZP3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Protein kinase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_45890</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="549"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="3">
        <location>
            <begin position="1"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="362"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="522"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="576"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="364"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="465"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="534"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="593"/>
            <end position="617"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV58566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1106" mass="116518" checksum="BACB321BEA32F1FC" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZW2</accession>
    <name>A0A518IZW2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PGL/p-HBAD biosynthesis glycosyltransferase</fullName>
            <ecNumber evidence="2">2.4.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_46580</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.4.1.-" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02522">
        <property type="entry name" value="GT_2_like_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026461">
        <property type="entry name" value="Trfase_2_rSAM/seldom_assoc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04283">
        <property type="entry name" value="glyco_like_mftF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="7"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="229" mass="24963" checksum="C2C5308C4C93B641" modified="2019-10-16" version="1">MTPAEISVVIPALNEAENIDRCVRSVAAAGEVIVVDGGSDDATAEIAAAAGAKVIVSSSGRATQQNAGAKVASGAVLLFLHADNHLAADAIEQVCNALTEQPERWGGAMEQRIESAGIAFRLLEWGNAWRVRLRGLPFGDQAIFVRRDAFQRVGGFPDEPIMEDLILSQRLRQIARPLILPGPVFVDPRRWQQRGIVRQTFRNFALQIAFALGVSPRRLRQYYANHQGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZY4</accession>
    <name>A0A518IZY4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Glutaconyl-CoA decarboxylase subunit beta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">gcdB</name>
        <name evidence="9" type="ORF">Mal33_46730</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006814">
        <property type="term" value="P:sodium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005661">
        <property type="entry name" value="OadB_MmdB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35806">
        <property type="entry name" value="PTHR35806"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03977">
        <property type="entry name" value="OAD_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015658">
        <property type="entry name" value="MmdB_OadB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01109">
        <property type="entry name" value="Na_pump_decarbB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 7" id="KW-1003">Cell membrane</keyword>
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        <source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
    <sequence length="388" mass="40832" checksum="1F80D2BA4D5B5D6A" modified="2019-10-16" version="1">MDILLEFINTTGFAAMSPGNAIMILVGIVFIGLAIVKDYEPLLLVPIGMGAIVGNIPVMEGMAMGVYDHHRWIIEDGGVEYQPGSVLSYLYLGVSLGIYPPLIFLGIGAMTDFSTMLSNPKLTLLGAAAQIGVFATFLGAVWLGFTLPEAGAIGIIGGADGPTAIFLAAKLAPDLLGAIAIAAYSYMALVPVIQPPVMKLLTTREERLIRMKPPRKVSKRERMIFPIAAFLICALIAPGAITLLGMLFFGNLLKESLVTERLANTARTAFIDIVTILLGFSVGASTQADTFLKPQSLLIFGLGALSFVIATASGVMFAKLMNRFLTDKINPLVGAAGVSAVPDSARVVQMVGQQADPHNFLLMHAMAPNVAGVIGSAIAAGVLWSVLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J010</accession>
    <name>A0A518J010_9BACT</name>
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        <submittedName>
            <fullName evidence="3">YCII-related domain protein</fullName>
        </submittedName>
    </protein>
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
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                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
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                <person name="Lage O.M."/>
                <person name="Pohl T."/>
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                <person name="Overmann J."/>
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                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF03795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="115" mass="12808" checksum="800F06F7194EAE5A" modified="2019-10-16" version="1">MMLIYGSEEGWTEPEREACMRESMAICDELAQQGKWIASSPLHSVTTATSVRVREGKRQVTDGPFAETTEQLGGYYIIDVDDLDEAIAIASRLPPAKKGTVEIRPLFPLPEREPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J092</accession>
    <name>A0A518J092_9BACT</name>
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        <submittedName>
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    <gene>
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    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
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                <person name="Overmann J."/>
                <person name="Amann R."/>
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                <person name="Devos D.P."/>
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                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="9 10">Mal33</strain>
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
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        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
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        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
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        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00120">
        <property type="entry name" value="HATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
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    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
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    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
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            <end position="81"/>
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        <location>
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    <feature type="domain" description="Cation_ATPase_N" evidence="8">
        <location>
            <begin position="9"/>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
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        <source>
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        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV58752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="900" mass="96326" checksum="9BFC3A5501969303" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0G2</accession>
    <name>A0A518J0G2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">Mal33_48470</name>
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    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022147285" evidence="1">
        <location>
            <begin position="25"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="245" mass="26963" checksum="7EB7058B81C98B3F" modified="2019-10-16" version="1" precursor="true">MLLRSLIASLCATVCVSFSCPVSAEETATLIFEDDFQRNESQEQTDEVGNGWKTNSKARAGGNKQVDLRDGAMYIYIHETADHGVSVVQPAEFRDGRVEVKFMLEDDRDSLGLNFADLKFKEVWAGHLCRVDIGTKAVAITDLKTGVMDLKIRTQRKAGTLPAEQQKMLKTKTKRVANKLETGKWYHAVATIVGDTLSVSIDGKEIASFSSPGIAHPTKRMLRLAVKRNVVVDDLKIYSLGGGKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0H2</accession>
    <name>A0A518J0H2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Planctomycete cytochrome C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Mal33_48710</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011429">
        <property type="entry name" value="Cyt_c_Planctomycete-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011444">
        <property type="entry name" value="DUF1549"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022655">
        <property type="entry name" value="DUF1553"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07635">
        <property type="entry name" value="PSCyt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07583">
        <property type="entry name" value="PSCyt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07587">
        <property type="entry name" value="PSD1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022213449" evidence="5">
        <location>
            <begin position="21"/>
            <end position="1045"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="6">
        <location>
            <begin position="23"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV58846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1045" mass="116468" checksum="B80D270DDB62F434" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0L7</accession>
    <name>A0A518J0L7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phosphoserine phosphatase 1</fullName>
            <ecNumber evidence="1">3.1.3.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">pspA_3</name>
        <name evidence="1" type="ORF">Mal33_49040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.3.3" evidence="1"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036424">
        <property type="term" value="F:L-phosphoserine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="SSF53254"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="201" mass="23042" checksum="7F37B06304321310" modified="2019-10-16" version="1">MQRFAQHPLPQIFVARHGETEWSRNRQHTGLTDIDLTDRGVHDAQRLGRRLENLTPDAVFTSPLRRASATCRFAGYSEMAVVDPDLVEWDYGQYEGKTTREIQQQRPGWNLFSDGCPAGETLDEVADRARRVIQRIRAIDGNVLIFSHGHMLNVLAACWIELEPRFGERFFLDPATVSILGYHHDRDDPVIRMWNSGGNEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0T8</accession>
    <name>A0A518J0T8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Arylsulfatase</fullName>
            <ecNumber evidence="10">3.1.6.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Mal33_49880</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="PTM">
        <text evidence="7">The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sulfatase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.6.1" evidence="10"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004065">
        <property type="term" value="F:arylsulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004423">
        <property type="term" value="F:iduronate-2-sulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16030">
        <property type="entry name" value="iduronate-2-sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035874">
        <property type="entry name" value="IDS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0106">Calcium</keyword>
    <keyword evidence="5 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021715041" evidence="8">
        <location>
            <begin position="27"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase" evidence="9">
        <location>
            <begin position="35"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="modified residue" description="3-oxoalanine (Cys)" evidence="7">
        <location>
            <position position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR600917-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV58963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="494" mass="54937" checksum="19CEA18851B97F20" modified="2019-10-16" version="1" precursor="true">MGNQSIVLRMCLAVLSTAVCTWQVLATDTQGRDRPNVLFIAVDDLACTLGCYGNLVAKTPNIDRLAAEGTCFQRAYNQLPLCNPTRASVMTGLRPDQIKVYDLDRHFRDQLPDVVTLPQAFQAAGYFAARVGKIYHYNVPASIGTDGFDDPPSWNRTVNPKGRDKTDEALVFNAEPHRKISGALSWLAADGRDEEQTDGMIASEAIKIMREKKDQPFFLGVGFFRPHTPYVAPKKYFEMYPLDSLRLPYAPPGDRHDIPTAAFAHNCPVPNYGLDRKTLLQATQAYYACVSFVDAQVGRLLDAVEELGLSKETIVVFWSDHGYHLGEHDGVWQKRTLFEQGARAPLIVRVPGQKSRGDCRQIVEFVDIYPTLTDLAAIPSPPGLAGRSLRPLIDNRQADWDGFAVTQVLRPADARLSDPVMGCSIRTHRYRFTEWGEGKHGVELYDHQSDPNEFHNLAVDHDAAATAVIDRLRPLLRSKASGKTPTVPVNPARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0U9</accession>
    <name>A0A518J0U9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Zinc-type alcohol dehydrogenase-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_49940</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08252">
        <property type="entry name" value="AL_MDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014182">
        <property type="entry name" value="ADH_Zn_typ-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002364">
        <property type="entry name" value="Quin_OxRdtase/zeta-crystal_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02817">
        <property type="entry name" value="adh_fam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01162">
        <property type="entry name" value="QOR_ZETA_CRYSTAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="PKS_ER" evidence="2">
        <location>
            <begin position="10"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU364000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="335" mass="36015" checksum="D598AD08A1C3F0AE" modified="2019-10-16" version="1">MKAIGYKTAGPITAPDALIEFESASPELQPHDLLVEVRGISVNPVDVKVRASQIPDSGTKIIGYDAAGVVRQIGSEVSRFKVGDEVFYAGDITRPGTNAEFHAVDERIVGIKPSSLGFAEAAGFPLTSITAWELLFDSLAVEEGAGEGESLLVIGGAGGVGSILIQLAKKLTGLTVIATASRPETIQWVEKMGADHVINHRESLVDQLKTLSLQPRYVASLTGTDGHFPAIIELIQPRGHVAFINDPQTLDINAGKPKALSFSWEFMFARSMFQTDDMEVQHQLLNRVSQMIDDGTLLSTVNNNLGKISVETLKQAHTEQESGRAIGKNVLDGFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0Z0</accession>
    <name>A0A518J0Z0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_50290</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="97" mass="9845" checksum="FB3011C0F1C3815A" modified="2019-10-16" version="1">MTVVRGFAITLTSGLFFGGVGGGLGYLLGSVAPDYYRTVFRLAPEVAFNASQLGLGLGVTQGTATGLIVGLVIVVLVAWYSSQTAGSLASGGEERTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J126</accession>
    <name>A0A518J126_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_50570</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="88" mass="9984" checksum="AEE3F1231EF585C9" modified="2019-10-16" version="1">MHGETVSAAFFAPWEPDVEPYIRIATGDYSELCKAHSRDDALAAYLHSLAHELVHYWQWIETGLITERGVLVRASNIVDRYATTTDHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J130</accession>
    <name>A0A518J130_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_50710</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="85" mass="9331" checksum="1455E022675870BB" modified="2019-10-16" version="1">MRARIASREEDMSPDGKLEILMQDDGDVIVNVKPSREDPHYRGSPFGVSVEFCSVGSGGGRSIHTLKALRDLFSAIEKDNAENPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J141</accession>
    <name>A0A518J141_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RNA polymerase sigma factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_50840</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014331">
        <property type="entry name" value="RNA_pol_sigma70_ECF_RHOBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02989">
        <property type="entry name" value="Sig-70_gvs1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="2">
        <location>
            <begin position="15"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="3">
        <location>
            <begin position="110"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV59059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="178" mass="20771" checksum="6E51E194F8E9A1A2" modified="2019-10-16" version="1">MDEETADKHEIFLTLFTANEAAIRAFVRRMVPTRQDSADVMQGIALVLWRKFHELDDRDGFRKWAFSVARYESLGWLRDKCRDRHVLSEDVLNVVAEESARRESWLAEQRDALDACLEKLPQLQRQLVLAAYAPEAEIQQVAQQSGRTVAAFYQWLHRIRLQLVECTRRTLQAEGCHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J154</accession>
    <name>A0A518J154_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Type-4 uracil-DNA glycosylase</fullName>
            <ecNumber evidence="3">3.2.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Mal33_50870</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolyzes single-stranded DNA or mismatched double-stranded DNA and polynucleotides, releasing free uracil.</text>
            <dbReference type="EC" id="3.2.2.27"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.27" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004844">
        <property type="term" value="F:uracil DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023875">
        <property type="entry name" value="DNA_metab_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025404">
        <property type="entry name" value="DUF4130"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005273">
        <property type="entry name" value="Ura-DNA_glyco_family4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005122">
        <property type="entry name" value="Uracil-DNA_glycosylase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036895">
        <property type="entry name" value="Uracil-DNA_glycosylase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13566">
        <property type="entry name" value="DUF4130"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03167">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00986">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52141">
        <property type="entry name" value="SSF52141"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03915">
        <property type="entry name" value="SAM_7_link_chp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00758">
        <property type="entry name" value="UDG_fam4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03914">
        <property type="entry name" value="UDG_fam_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDG" evidence="9">
        <location>
            <begin position="300"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV59062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="467" mass="52327" checksum="111B1E1ED25B7112" modified="2019-10-16" version="1">MQSIHVDTFDDWRDAARRLLASGVSPTDVQWIGGAERSLFASDAPTVSPDASTAATVPNVPKAFLELARYVASHRASGRWSLLYRTLWRLTHGERHLLQVTTDDDVHQLMQMRKGVSRDIHKMKAFVRFRKLETGGAEEQFVAWHRPDHRIVRLAAPFFARRFSGMHWSILTPDESVTWDQTSLHYGPGVPASEAPDEDALEDLWKAYYASIFNPARVKVAAMKREMPVRHWPTLPEATLIDDLLRQAPARADAMIQTNEGFAETAAHFMPERGDLVSLRHAAATCRACSLHQCATQTVFGEGSPSARIVLVGEQPGDREDIEAHPFVGPAGKLLDEALKQAGIDRRDVYITNVVKHFKFMETETPRGKRRLHQKPDSREIYACRPWLEAELAAIGPQVVVCLGATAAQALFGRDFGITKDRGKVMRTDWCDITIATWHPAAILRMQDAVRQAQMRTQLVDDLASVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1M8</accession>
    <name>A0A518J1M8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">von Willebrand factor type A domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_52630</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd01467">
        <property type="entry name" value="vWA_BatA_type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033881">
        <property type="entry name" value="vWA_BatA_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00092">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VWFA" evidence="1">
        <location>
            <begin position="93"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="345" mass="37646" checksum="B4743298EDA802FC" modified="2019-10-16" version="1">MLTFDYLWVFLLFPLPWLLRALLPPRQSQQVSVRVPFGNRLAEAMTRSPVAVIAAAAPTRWILPAILWSLVLAAAARPQWIEPPITKELPTRDLLLLVDLSGSMDQKDFTNNSGQKVDRLAAVKEVLGEFLDRRQGDRVGLVVFGDAAYLQAPFSTDLELSRRLLDECQVGMAGPRTALGDAIGLGVGLFDESDAQAKTIIALTDGNDTKSKIPPIEAARVAAQRDIHIHTVAIGDPTTVGEDVLDEQALRDVASATGGFYFFAADRKSLVGIYDELDKIETRKVKTVSHRPRTDIYYVPLAVALLLSMASKFAAALSRRTPPELAAQTTRVHVNPITGSLEVDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1V3</accession>
    <name>A0A518J1V3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative glycosyltransferase EpsJ</fullName>
            <ecNumber evidence="2">2.4.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">epsJ_1</name>
        <name evidence="2" type="ORF">Mal33_53440</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.4.-.-" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="6"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="290" mass="33092" checksum="882A37B7866BB8B8" modified="2019-10-16" version="1">MTPTVSVLMTTYNREKYVSFAIESVLGSTCNDFELLIVDDCSTDGTVEIARRYEQKDSRIRVVVNEKNLGDYPNRNRAASLARGYYLKYVDADDYIYPTGLQTLIDMMSRYPEAGYGLCSLLQLRNAPFPLCLSPTEAYRQHFFCSPIFHKAPLSSIIKKSAWDAVGGFSKEKMVSDADMWHRLSMQFDVVLMPLGIVWYRQHDDQEVSDLLRAPVHYAMRYDAVVQRALSSENAPLTVEEKQDICNRFRRMSVRQMIKNLVRGRLKEASLYASNALAFGRICTEVAGRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1W2</accession>
    <name>A0A518J1W2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha-D-kanosaminyltransferase</fullName>
            <ecNumber evidence="2">2.4.1.301</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">kanE_2</name>
        <name evidence="2" type="ORF">Mal33_53550</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.4.1.301" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="170"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="362" mass="41502" checksum="B85F7901E50C7367" modified="2019-10-16" version="1">MKVFFASTIGAAPYEDPNFKQQVQWSNLKLDEFEHVFLNNEPLSSSKTLDAPHIVEELDSFGADVVIVYGYWQRFQQRVHRWTRDHKALLYYISDSEIHRQESKLKRFLKSLRSKRVFRNVDRFLTVGNANEFYYHSLGVPTERMTRMQFSIDVQEFDVAYECRHELRQETRNRLGVSNDCTVLSVAGKLVSWKRQRDAIEAIARIDRTRDVLLVLMGSGPDELELRDLVNQICPDRVHFAGFVPPTDLPNYYLATDIYLHCSNYEPHSLAISEAIYLGLPLILSSRCGSYGPLDDLQPGKNGFVYPVGDVTALAKSVERMIENVELRELFAAESRAYAGNAQERAHQSFLTQALRADGLIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J233</accession>
    <name>A0A518J233_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_54390</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="228"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="247"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="349"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="723" mass="80084" checksum="BDCF066E08598B65" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J241</accession>
    <name>A0A518J241_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_54330</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="336"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="396" mass="43980" checksum="182BD4B8AAE5FC41" modified="2019-10-16" version="1">MSSVWQRWRDKTPQSEREYQQQIDPLRAAAPVPVLWLFGKTGSGKSSVIHFLTGAEQATIGEGFRPETKASRRFDFPDSTDPLMTFLDTRGLGEAAYDPIEDIAAYSQTTQLMIVTVRVSDHALVDVLEPLRRIRRATPQRPVLLVLTCLHESTGAIDLSEGIDPFDAPPASEDPAAAEPLPPIPAELQTLIDRKSEQFAGLYDHLVPVDLTRLEDGFADPEFGGRRLRQAILQYLPHAYRQSMLSLASDAQQHRSKRQRRARWQILASSSLAATAGAVPVPWVDIPVVLAIQSHLAIRLGKIYEQELTASHWAALSSAAGSRIATRMALREVLKLIPWVGMAAGAASAFAFTYALGMSWDWYFASLHQGRAPSVDKLREIFADELQRGHELWKAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J290</accession>
    <name>A0A518J290_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Carboxylesterase NlhH</fullName>
            <ecNumber evidence="3">3.1.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">nlhH_5</name>
        <name evidence="3" type="ORF">Mal33_54840</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.1.1" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080030">
        <property type="term" value="F:methyl indole-3-acetate esterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13202">
        <property type="entry name" value="EF-hand_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="SSF47473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021995857" evidence="1">
        <location>
            <begin position="18"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="2">
        <location>
            <begin position="72"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV59449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="402" mass="44428" checksum="AACD96E3F4D2F3CD" modified="2019-10-16" version="1" precursor="true">MKYNFALLLCSSLIVSAGFCQESERPAGAFSDRRAALLKRFPESDTNKDGILSARELAAHLQKQRSGPEGKERLKQMLKRFPKADANKDGELSWEEVREYQAANAKNRSPQTRRNRAPKVVAPVPDVAYGDHPLQRFDLWPVPDAKQPTPLVIFIHGGGFRGGDKSLIRRETIDKFLDAGVAVAAMNYRLSDSGPYPIMMHDAARGLQTIRHRSDQWNIDPQRVVCYGGSAGAGISLWLAFHDDLADPNSDDPVARQSTRIVAAGAMNGQPAYDIHLFREWFGLPELQPGPALPAFVGIEDESEFDKPEIRALMKEASPISHLSEDDTAAVYMFYSRPNVPVTLETESSVWVHHVRLGLEMQKAMKPLGLQCIVTAPDIKADNPYDSLEAFLIAKALGASGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J2D4</accession>
    <name>A0A518J2D4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_55250</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="107"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="245"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="245"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="420" mass="46611" checksum="C0339E3F23F70001" modified="2019-10-16" version="1">MDEQDFKDLYGLMRGNSDATSVMDAQGLFALKDYQQTLEKLQGIQQRYESSKIRVMRTKIEESGGRKSSEQEAKERRLQKKQTRYREVMEKLDEMQAALPTLIQRAEARKAREQSQQAAVVDQSHEDTIDGEASEELTHSGEEQSPSLEQFIREFVAAPAATNQRDLIDRCFKVRPVSDAQDVRAGELYFIDGGGQTYLALVRKSDNPERVRLKSAITGERLRTIDLPTFLKLGQRDRVVRLKPLLQNSGSSQRSQTSTSAPAPTPAQQSTAAAPPIEDDDDVVIGGNALQESAETAKILDKGAFSQLADAANRSGICPGADLIAHVRDRDFRLGNFQDALQTMEGIYGKFTAAAASRTAQLRQEDAAIQSGRVKMSPKDLAAKRARDAAQNQLVERARNRFSRVLDGLRVLLRKETGEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ILX0</accession>
    <name>A0A518ILX0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AAA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_00370</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13401">
        <property type="entry name" value="AAA_22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="1">
        <location>
            <begin position="56"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="673" mass="74953" checksum="5E3FF084E2161353" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IM48</accession>
    <name>A0A518IM48_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Hydroxypyruvate isomerase</fullName>
            <ecNumber evidence="4">5.3.1.22</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">hyi_1</name>
        <name evidence="4" type="ORF">Mal33_01190</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the hyi family.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.22" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008903">
        <property type="term" value="F:hydroxypyruvate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026040">
        <property type="entry name" value="HyI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013022">
        <property type="entry name" value="Xyl_isomerase-like_TIM-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01261">
        <property type="entry name" value="AP_endonuc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006241">
        <property type="entry name" value="HyI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="SSF51658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AP_endonuc_2" evidence="3">
        <location>
            <begin position="88"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="2">
        <location>
            <position position="177"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="2">
        <location>
            <position position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR006241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR006241-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV54172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="303" mass="33281" checksum="79156836D18F1BD5" modified="2019-10-16" version="1">MSLSRRNLLAAGGAALAAVATRQTVSRAEDVAKETAARDSSPAITKGRIHQSVMGWCFKPMPSIELAKHCKAIGIEAIEGIPASDYPAVTKLGLKISLVGSHGFQAGPLDPENHAMNEAKLREAIDTAVKFGAPSVITFTGMRKTGIDDRQATKNCLDLWKRVLPYAEANDITLVLEHLNSRDDTHPMKGHPGYWGDDVELCVDLVKQLDSPRFKLLFDIYHVQIMNGDIIRRIREYHPLIGHYHTAGAPGRGELNDDQEINYPAVMRAILETGYSQYVAQEFIPTSNDPIASLREAARVCDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IM79</accession>
    <name>A0A518IM79_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Photosystem I assembly protein Ycf3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_01470</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024983">
        <property type="entry name" value="CHAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12770">
        <property type="entry name" value="CHAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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        </location>
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            <end position="1177"/>
        </location>
    </feature>
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            <end position="350"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="485"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="domain" description="CHAT" evidence="4">
        <location>
            <begin position="811"/>
            <end position="1175"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="697"/>
            <end position="724"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
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    </evidence>
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        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF12770"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="QDV54198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1177" mass="129450" checksum="CCEA68D98A81A3EF" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="6" xmlns="http://uniprot.org/uniprot">
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    <name>A0A518IM90_9BACT</name>
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            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
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                <person name="Spormann A.M."/>
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                <person name="Overmann J."/>
                <person name="Amann R."/>
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                <person name="Mascher T."/>
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                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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    </dbReference>
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        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
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        <property type="entry name" value="PKS_ER"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
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        <location>
            <begin position="14"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="334" mass="35514" checksum="ABA66D88C602A172" modified="2019-10-16" version="1">MTTIHAYAATKPGGLFELFDYDAGDVGPDDVEIQVESCGICHSDLSMLDNDWQITQFPFVGGHEVIGRVVALGSHTLGLAEGDLVGLGWTSRSCMHCDECLSGAQNLCRDARGTITHQHGGFADRVRCHWGWANKIPEGVDAASAGPLLCGGVTVFSPLVQHSLSPTARVGVVGIGGLGHMALQFCDAWGCDVTAISRGRSKEEEARKLGADHFVATEEDPKLQSQAGRFDLILNTTNAALPWDAYIAALAPGGVLHTVGAAAKVEASVSPMIMGQKSFSASPTGSIVTTRSMLDFAARHKITPMTEVYSMSDINEAFEKLRNGSPRYRLVLTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
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    <name>A0A518IMA3_9BACT</name>
    <protein>
        <submittedName>
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        </submittedName>
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        <lineage>
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    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
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    </dbReference>
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            <end position="43"/>
        </location>
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    <evidence type="ECO:0000256" key="1">
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="103" mass="11392" checksum="0E818DE3ADDD90C3" modified="2019-10-16" version="1">MYFTPGQTTAPNEKYPERDTNPSGNRYSNGAESENTPLSTPPIFEVTDPVEAELLALFRSLEPTGRNELLMVVARKGGCKASFALVLPSISFCQATCLQQRHW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMF9</accession>
    <name>A0A518IMF9_9BACT</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">Mal33_02300</name>
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    <organism evidence="2 3">
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    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="147" mass="16009" checksum="02C603C75B8712E0" modified="2019-10-16" version="1">MSNASPATLRSFNINLHGPQRSGESDPPETNAPAAVPTATTAPLSPLGGSFEQLCERLERLPRTHLELDGSFVHRGPAPPLHIDGMIYDANGQVQYVQLQGTSDHATWQELIDVLSSDKSKPPSVQLLQSGELLSLQSFERQEWKIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMI9</accession>
    <name>A0A518IMI9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
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    <organism evidence="2 3">
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    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="68" mass="7593" checksum="12AE58FEE3E957DD" modified="2019-10-16" version="1">MIRFAIDKQDRTSRSNHGRYGLIVLPPIVLPPIILPPIILPLIILPLIILPLIILPLIILPLIILPIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMJ8</accession>
    <name>A0A518IMJ8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Mal33_02450</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
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            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027359">
        <property type="entry name" value="Volt_channel_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="91"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="124"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="172"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="205"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="240"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="340"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="364"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV54295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="379" mass="43383" checksum="9A28E83583B4F937" modified="2019-10-16" version="1">MIHRTKEEPPIWLATRAAPVLFWASLLFLVCQAVAVVIFVDVPNLRESFTDNPAAEIEATESLDAIDPAADLPVEVPELVASDLSWEPIELATLILMGLIWPLVIAESVYHWRTRPWTRETRRFHFYSLLYCLCPSLRMCAQSLEMGNRLWLPGWGWRRADDRLRRRLERTFSMPMIWIALMILPVLVIELWLKTQVADYRWLRIALHVSTGVIWFSFAAEFILMASVAEKKLTYLKEHWIELAIILLPLLSFMRSLRLLRATGASKLIRLSQLNQIVRTYRLRGTAMRALRALILLDLFQRLTLRAPEKTIAKLQLQLEELETEAKQIRRKIGRLERTIRKQEAEASAPESEAAGLEADVDSSSSDAAGTRSATTGSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMW8</accession>
    <name>A0A518IMW8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">HTH-type transcriptional regulator YjdC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">yjdC</name>
        <name evidence="3" type="ORF">Mal33_03920</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="4"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="198" mass="21878" checksum="EC93D135DC1CD91C" modified="2019-10-16" version="1">MRGNVLREYLVETATTIFYRDGFRATGVDAIAKECNVAKKSLYNHFPSKDLLIAEVLRRRHVAWVESVERTIGAASGPEDAIMALFDATSRAVRTPKYRGCIFFNAAIEFPDACPEIGSIIDENVRYSHRRLVELATEAGLENPELVAIQIGVLRRGAQVTAMASGDAEVVGFAKELASQVIADAKRPKSKKRVRRKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IN78</accession>
    <name>A0A518IN78_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HTH-type transcriptional regulator MgrA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">mgrA</name>
        <name evidence="2" type="ORF">Mal33_04990</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12802">
        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00598">
        <property type="entry name" value="HTHMARR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="18"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="169" mass="19423" checksum="47886FF2299C9098" modified="2019-10-16" version="1">MDDLRHELKRCQPFASVAQEAIVSLARTGDQLDNQLSQFFRPRELTFSQYNLLRILDMEDRPLTCGEIGDRLVQIVPAVTALVDRLLRRDLVTRERSEEDRRTVYVAITDAGRKLVRPASEELREFEDNLINGLKQKEQKELIRLLQLVRASMSCAAKQRAASGNRQSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INJ1</accession>
    <name>A0A518INJ1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">BNR/Asp-box repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_06050</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004308">
        <property type="term" value="F:exo-alpha-sialidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011040">
        <property type="entry name" value="Sialidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026856">
        <property type="entry name" value="Sialidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036278">
        <property type="entry name" value="Sialidase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10628">
        <property type="entry name" value="PTHR10628"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13088">
        <property type="entry name" value="BNR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50939">
        <property type="entry name" value="SSF50939"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021719058" evidence="1">
        <location>
            <begin position="33"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="domain" description="Sialidase" evidence="2">
        <location>
            <begin position="114"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="395" mass="44060" checksum="A48EC9A353836B5C" modified="2019-10-16" version="1" precursor="true">MRVIQVLFKKSVAMFAWSAISLTCCESLLAQADAPVPQGVAAGVEKPMRISPRPGNDRNSEGDFIRLKDGRLMLIYTKFVGRSDHAEAELVARYSNDEGKTWTQDDESAIARGEDDANLMSVSLLRLQDGRIALFYVRKYKSPANAKYPFLDSILMQTSDDEAKTWTEPVHVSPADEPAYRVLNNDRVIQLKSGRLVAPVATHYLPGWPGWRNSAQIHCYLSDDLGKTWRTSKSTLESKLLAQEPGVVELKDGRIMMFCRSRDCQLVTYSSDGGETWTPLEKSNIPQPSASPATIERIPSTGDLLLVWNNGDDPLAKIKPTGRRPFTAAISSDDGATWKNVKNIGTDPDGWYCYTAMEFVGDHVVLGHCEFPKLNSFQITRFPVTWLYETAESSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INJ3</accession>
    <name>A0A518INJ3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_06190</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="341" mass="38620" checksum="39388E8E2C01F146" modified="2019-10-16" version="1">MNQSARIKHWKWIVPLPALLSLGFLCHNWYHKQQRPRFAIQYELVAPNAIDGYIEAGRDARVKLRYKLTNVGREPLRGIATDLGCTCQILKQPEDIFPNESDLLEFSLRAPSAGAIQRKIPILIESQRQPLVFIQVALRVPVLTPSFLHQQRELNISFIDGDSLGRRITVETIERADSDTWIAKLETTPPSLVNFTEPTVHERPNRDPALTHRTYLFEASAGQEIDSAHAGVYVLRDRSGAPLHKPQLIRVKRLPRFTNHPSSPVVRTGENTKILVLDRLGRSSLTVFRYDQELIAVTPGAVKNTFLVSLRKSTIDTKMTELELRSEDGSKVHIPLCFACD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INV7</accession>
    <name>A0A518INV7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">O-Antigen ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_07360</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007016">
        <property type="entry name" value="O-antigen_ligase-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04932">
        <property type="entry name" value="Wzy_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0436">Ligase</keyword>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="52"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="83"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="155"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="181"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="232"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="273"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="302"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="326"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="423"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="454"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="479"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="517"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="117"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV54771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="907" mass="98130" checksum="455449FF70CCFBB3" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INW0</accession>
    <name>A0A518INW0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HTH-type transcriptional regulator CymR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">cymR</name>
        <name evidence="1" type="ORF">Mal33_07400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030489">
        <property type="entry name" value="TR_Rrf2-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000944">
        <property type="entry name" value="Tscrpt_reg_Rrf2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33221">
        <property type="entry name" value="PTHR33221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02082">
        <property type="entry name" value="Rrf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00738">
        <property type="entry name" value="rrf2_super"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01332">
        <property type="entry name" value="HTH_RRF2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51197">
        <property type="entry name" value="HTH_RRF2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="140" mass="15126" checksum="8F84198A63A32C28" modified="2019-10-16" version="1">MSAKAHYACLAMLELALRHDEDRPVALREITARHSIPQPFLVQILQQLKVAGYVTSTRGSQGGYRLSVDATAISLLDICDAIGCGDAEQTPENADTTAEAQVLGATWRAASKAFRDVLASIRLEDLANDCSRADGAMFYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INX4</accession>
    <name>A0A518INX4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_07530</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="103" mass="10461" checksum="917E6C537FF46E23" modified="2019-10-16" version="1">MAAGTAGTGSPKLNCIRRDGGRSQDAVVTLLAADFAGPKFSNLLGGPRLDYGRCGVSDSQGNLYITGTATVPVGLSTARSTPNLPAPVPANNFVTKVDIKPGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INY5</accession>
    <name>A0A518INY5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">TGc domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_07710</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013589">
        <property type="entry name" value="Bac_transglu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018667">
        <property type="entry name" value="DUF2126"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002931">
        <property type="entry name" value="Transglutaminase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08379">
        <property type="entry name" value="Bact_transglu_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09899">
        <property type="entry name" value="DUF2126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01841">
        <property type="entry name" value="Transglut_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00460">
        <property type="entry name" value="TGc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TGc" evidence="2">
        <location>
            <begin position="172"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="604"/>
            <end position="647"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1157" mass="130548" checksum="908C702AE022918D" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP28</accession>
    <name>A0A518IP28_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 9">Argininosuccinate synthase</fullName>
            <ecNumber evidence="2 9">6.3.4.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 9">Citrulline--aspartate ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9 10" type="primary">argG</name>
        <name evidence="10" type="ORF">Mal33_08140</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + L-aspartate + L-citrulline = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10932"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57472"/>
            <dbReference type="ChEBI" id="CHEBI:57743"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.4.5"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 9">Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the argininosuccinate synthase family. Type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.5" evidence="2 9"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00113"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004055">
        <property type="term" value="F:argininosuccinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01999">
        <property type="entry name" value="Argininosuccinate_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00005">
        <property type="entry name" value="Arg_succ_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001518">
        <property type="entry name" value="Arginosuc_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018223">
        <property type="entry name" value="Arginosuc_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023434">
        <property type="entry name" value="Arginosuc_synth_type_1_subfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024074">
        <property type="entry name" value="AS_cat/multimer_dom_body"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11587">
        <property type="entry name" value="PTHR11587"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00764">
        <property type="entry name" value="Arginosuc_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69864">
        <property type="entry name" value="SSF69864"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00032">
        <property type="entry name" value="argG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00564">
        <property type="entry name" value="ARGININOSUCCIN_SYN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00565">
        <property type="entry name" value="ARGININOSUCCIN_SYN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3 9" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 9 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="7"/>
            <end position="15"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>L-citrulline</name>
            <dbReference type="ChEBI" id="CHEBI:57743"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>L-citrulline</name>
            <dbReference type="ChEBI" id="CHEBI:57743"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="117"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="121"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="125"/>
        </location>
        <ligand>
            <name>L-citrulline</name>
            <dbReference type="ChEBI" id="CHEBI:57743"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="178"/>
        </location>
        <ligand>
            <name>L-citrulline</name>
            <dbReference type="ChEBI" id="CHEBI:57743"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>L-citrulline</name>
            <dbReference type="ChEBI" id="CHEBI:57743"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="264"/>
        </location>
        <ligand>
            <name>L-citrulline</name>
            <dbReference type="ChEBI" id="CHEBI:57743"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="276"/>
        </location>
        <ligand>
            <name>L-citrulline</name>
            <dbReference type="ChEBI" id="CHEBI:57743"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00029916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV54849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="404" mass="44460" checksum="8F949159562CED53" modified="2019-10-16" version="1">MKSCVLAYSGGLDTSVILGWLQDQGYEVHAVYVDLGQPCEDRAATLKKAQDAGAKSARIVDVREELCRDFAFPVLSWQAKYESIYLLGTSIARPLISKVMLEVAREVGATAYAHGATGKGNDQCRFQLAAEALDPSIEMIAPWRIKEFRDLFPGRTELIAYCEEKGIPVKASSSKPYSSDENVLHISYEAGQLEDLTVNGVELVDFGMTVSPQAAPDKPEEVTIDFEAGVPVALNGKTVSALEMVESLNEIGGRNGVGRIDMIENRFVGMKSRGVYEAPGMTVLYDALLNVEQLTLDRDLVRLRDKLAVEVSEMVYYGFWYTPKFDALLAFINEARKPVTGSVTLQLYKGNIIVSSRQSPNSLYDEEIATMEGGGSYNQDDAEGFLRIHGLPSRVQGRVSPRPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPC9</accession>
    <name>A0A518IPC9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_08900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011474">
        <property type="entry name" value="DUF1580"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07618">
        <property type="entry name" value="DUF1580"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="74" mass="8166" checksum="7981D7B820470693" modified="2019-10-16" version="1">MTANSQYLPLHSAVEQVINAPVNRVTAWRWATRPNRYGVQLQSWIIGGKRRTTVAAAERYIAESTAAANAAPRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPD5</accession>
    <name>A0A518IPD5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Peptidylprolyl isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_09150</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000297">
        <property type="entry name" value="PPIase_PpiC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027304">
        <property type="entry name" value="Trigger_fact/SurA_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109998">
        <property type="entry name" value="SSF109998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50198">
        <property type="entry name" value="PPIC_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0697">Rotamase</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021725548" evidence="3">
        <location>
            <begin position="27"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="domain" description="PpiC" evidence="4">
        <location>
            <begin position="213"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="322"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV54949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="383" mass="43582" checksum="DE3E07F6E5890979" modified="2019-10-16" version="1" precursor="true">MIVGLKYFSTLALLASLCLSGSWAVAQPPGIAFSDVELPSEPTAMIANVDGVPILLRDVAETVDNNIQQIIASSGRKPSPEELKMARTTLIRRELRKEIQGKMMYRAFVRKMTGTQPEDKRAEMELSITSNVRKMFYEQQLPQLLEQYKLETVSEADAMLRKSGSSLEQQERRFVESILGQEYLRGEMDKDPEIPLPDMKFYYEQNTEKFSRNARARWEQLTVLFSRFETKQEARDAIIRMGNEAYYGGNVQAVAKRLSQEPLADETGGLHDWTNKGSLASDILDQQIFSLPVNKLSQIIEDDNGFHIIRVLEREEAGMLSFADAQDEIRKILKENIQQEQQKNLITELERKIPVWTIFPDDVPKSMPLESAAVASAETKSLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPF5</accession>
    <name>A0A518IPF5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_09200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005240">
        <property type="entry name" value="DUF389"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20992">
        <property type="entry name" value="PTHR20992"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04087">
        <property type="entry name" value="DUF389"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="295"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="330"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="369"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="394"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="434"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="469"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="491" mass="53394" checksum="5C3400CA96E019C5" modified="2019-10-16" version="1">MRARFEGDLFVSQLILLASSVQQLDRCLPLLAHFGSTPASSVTIWVIAEAKSSLAAYANRCSEQLSVESRVQCVTENETDLLHRLSQCRHVDWFVMPYAGEQQAFFSNLFERSPCRTMLLDPGAEFSGEVGRIVELLNDESDSIGRICRANPKMAERKLAFDAPDELTAADSARRRELLVDRLAELQLQSNDLVVTAVQRTTKPNGDLAIARQLLDLDIPATVVILRHRMGWVEHTWSSIEKKIFEWSPPMEREARMELAENLADNSSLQFEFVAMMCAATCLAAFGLVQNSAAVIIGAMLVAPLMTPIMGAGLALAYGNRPLFGRAGMTVGVGFLCALATSFLFGLLVRMVQGAEVTPEMWARSNPSILDFLVGLVGGSAAAYARTRSHLSSALAGAAIAAALVPPVATAGLQLAFLPIATTPTRCLPVTGPLLLFTANVLTIMVGSSFILWLSGIRGDHRFGKKQRWANRALMLLLILTSLVLVVVVEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPJ1</accession>
    <name>A0A518IPJ1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Planctomycete cytochrome C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_09770</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011429">
        <property type="entry name" value="Cyt_c_Planctomycete-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011444">
        <property type="entry name" value="DUF1549"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022655">
        <property type="entry name" value="DUF1553"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000421">
        <property type="entry name" value="FA58C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00754">
        <property type="entry name" value="F5_F8_type_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07635">
        <property type="entry name" value="PSCyt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07583">
        <property type="entry name" value="PSCyt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07587">
        <property type="entry name" value="PSD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50022">
        <property type="entry name" value="FA58C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F5/8 type C" evidence="1">
        <location>
            <begin position="456"/>
            <end position="563"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="930" mass="103435" checksum="4F08F8F675EE1F29" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPV3</accession>
    <name>A0A518IPV3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_10710</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="158" mass="16812" checksum="A8E62F3C736C87E4" modified="2019-10-16" version="1">MPTIHPAFRITAFTNTAATFLLLVSAIGCGDSLPSYEMVPVSGVVNLDGAPVANANLVFYSETLPRAFATTDNSGTFQLETPQYGEGIPEGSYLVQIQSSDQTIDSQSGKSVSIPIVYGENGIEVITISSDGEKTFTFDLKSRPKKGDYVSENSMAEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPV6</accession>
    <name>A0A518IPV6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">All-trans-phytoene synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">crtB_1</name>
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        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
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    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="1 2">Mal33</strain>
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    </dbReference>
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        <property type="entry name" value="SQS_PSY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01212">
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    </dbReference>
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        <property type="entry name" value="SSF48576"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03464">
        <property type="entry name" value="HpnC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="299" mass="33797" checksum="A9D8173488CF8F27" modified="2019-10-16" version="1">MPSPASPLENSNAAPPSLVESQAYCRRYARARRENFVVASCCLPRDLRQDFYNLYTYCRTADDLADEIASPAESLYLLDLWQQQLESCYDDQPTHIAFVALQSTIERFSIPREPFLDLLTAFRRDQSESRYATQESLAEYCRYSANPVGHLILHLADAFEPSRASLSDSICTGLQLANHWQDVGEDFRRGRVYLPQDRCAALGVSEAMLAAPTASAELKSLVSEQVEIASRLFDEGRPLLEQVPRWLRLDLELILAGGEAALQAIRHADFDILGKRCKVPLKTRLAWVARTAWLQWSAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQ06</accession>
    <name>A0A518IQ06_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_11210</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetia</taxon>
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            <taxon>Rosistilla</taxon>
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    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
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                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">Mal33</strain>
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        <property type="molecule type" value="Genomic_DNA"/>
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            <end position="25"/>
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    <feature type="chain" id="PRO_5022201308" evidence="1">
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    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="324" mass="36242" checksum="833CC2192A4FA2C1" modified="2019-10-16" version="1" precursor="true">MNLLKRTRVQTWITLLIVCSANIQAAIAEDLITIDNGSIKVGIDREKGAAITWLSSAGYPRNLVNIADPGRLIQQSYYAGRVIDRTADGQHKSWSPWSWNPIQGGGVGSVKGQGSWARVTVFEKREDALYSETIPKLWDMADEEAEAVMRQWTTMESNMPGVVRVRCEFQAMRREGDRWGNARMNPQEVPACYFTRNFADVRSYLGSGKWRPEHQRPGPPWGKASPPRQAMAMFEASGQGVALFSPSATEHWNFGPHAAGLSDDPTAGPCMHVAPVSRVLMGPKSIYRYRYWLIVGNETEIAARLDTLWNLYATEKAELIESPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
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    <name>A0A518IQF9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">von Willebrand factor type A domain protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="5" type="ORF">Mal33_13020</name>
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    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
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                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
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                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5 6">Mal33</strain>
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    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="entry name" value="VWF_A"/>
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    </dbReference>
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    </feature>
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        <location>
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            <end position="180"/>
        </location>
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        <location>
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    </feature>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="QDV55331.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="796" mass="87842" checksum="044C5934255AD074" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
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    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Wiegand S."/>
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                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
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                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
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                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">Mal33</strain>
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    </reference>
    <dbReference type="EMBL" id="CP036318">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <location>
            <begin position="26"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="173" mass="18711" checksum="049255AF1AF78E66" modified="2019-10-16" version="1">MKTLLFTSAIISMTFSLVGCKDAGPNVETSAPPATVETHDNHEGHDHPSEGPHHGGLIELGNEEYHAELVHDEDIGSVTIYVLNAAATEQIPIDSTEITINVEHEGKPEQFALVASPDATDPQGKSSRFVSTDAELGEHLDEEGADPKLVLTIDGKSFRGTIEHDHDHEDHDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQS2</accession>
    <name>A0A518IQS2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_14140</name>
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    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
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                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
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                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="181"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="325"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="337"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="351" mass="39530" checksum="4E7C5CA45D8D5C35" modified="2019-10-16" version="1">MNRITFLIALVALIAIGSLTPRDGWAQPIEKVSQSGPVSVAISLDPPEPLIGDPVTLRIEVQAEQEVEVLMPEFGEALDRFAIVDFVPREAIDDAGKTILSQQYRLQPAGSGKQAIPPILIEYVDNRPDQRQAPEGFDAYEILTDAIPFTVQSVLPDDVAADLNPPLGRLEPRQPPAPARWPWVLALVAFCAAASPFAWRAYTDWQRRRRRKSAYEVARWRLDQLLRQPRISADEIDTFYVDLSNLVRHYLEDRFELRAPELTTEEFLNSLQASPDMTRDHQSLLREFLRQADLVKFAGAVPSDADIARSIDAASQFLEETRENAPLMEFDQDEPQHSEPQTPAATEVRNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IR11</accession>
    <name>A0A518IR11_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_15010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="143" mass="15702" checksum="1AEEE82688F445E6" modified="2019-10-16" version="1">MCFRHTFNRCQSPPRRGCRRGGGSMIELVVSATLLVALIGTFAPMSLSAGRMWQQTRHHQLALDELSNHLDRLLALPEDQRGAELQSLQPSAAAQAALPAASLTAVQVSDEDGTRITIEINWQRQTPSQPLSLTGWIRGTDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IR55</accession>
    <name>A0A518IR55_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Globin-coupled histidine kinase</fullName>
            <ecNumber evidence="3">2.7.13.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">gchK</name>
        <name evidence="3" type="ORF">Mal33_15460</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.13.3" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="2">
        <location>
            <begin position="156"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="371" mass="40694" checksum="7262D587F8E8732C" modified="2019-10-16" version="1">MHDNKTLFVALQEGANRNVVNRAFIIPHQDESLDIYDVLILDESHRNNGQAAVAAILQHDLTTYAAIILDSGFPSGTAESLLAQLSDDTSCLVATSRAGIKATFEDLSQEALAGDPQSSPTDLLKEMYAMLSSGVEPEQRQSQRERLESIGLAVASVAHETRNALQRIQVHLDLLRMNEGDALQRMNDLTSIEQANRCLWTLFNELQDFSAPLQLQCESVSVRGLVDSSWESLRGREGWDRAELKLDIPNVCATVDPIRIEQVLRNLMENAIDACDDKASIEIAAASIQLNGREALQITVRDNGSGIRPEFRQNAFEPFYTTKSRGSGLGLPICKRIVEAHGGRLGIDPKIVDGTAFLIVLPVGRSDACDC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IR94</accession>
    <name>A0A518IR94_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">10 kDa chaperonin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_15870</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Heptamer of 7 subunits arranged in a ring.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the GroES chaperonin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00320">
        <property type="entry name" value="cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.33.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020818">
        <property type="entry name" value="Chaperonin_GroES"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037124">
        <property type="entry name" value="Chaperonin_GroES_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10772">
        <property type="entry name" value="PTHR10772"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00166">
        <property type="entry name" value="Cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00297">
        <property type="entry name" value="CHAPERONIN10"/>
    </dbReference>
    <dbReference type="SMART" id="SM00883">
        <property type="entry name" value="Cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV55610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="110" mass="12405" checksum="D542E254F0316F2B" modified="2019-10-16" version="1">MAKKRPQAFEYVEPIGPRVLVRKDEPKRETKGGIALPDAAEIPTITGRIVTISAMVEQDDEMPLRQYDKILFHPKDAIPVDFESDNQLFVVPVEDVVAVFRRNDPSEDAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRG7</accession>
    <name>A0A518IRG7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Putative glucose-6-phosphate 1-epimerase</fullName>
            <ecNumber evidence="3">5.1.3.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">yeaD</name>
        <name evidence="6" type="ORF">Mal33_16610</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>alpha-D-glucose 6-phosphate = beta-D-glucose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:16249"/>
            <dbReference type="ChEBI" id="CHEBI:58225"/>
            <dbReference type="ChEBI" id="CHEBI:58247"/>
            <dbReference type="EC" id="5.1.3.15"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the glucose-6-phosphate 1-epimerase family.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.15" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047938">
        <property type="term" value="F:glucose-6-phosphate 1-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09020">
        <property type="entry name" value="D-hex-6-P-epi_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008183">
        <property type="entry name" value="Aldose_1/G6P_1-epimerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025532">
        <property type="entry name" value="G6P_1-epimerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01263">
        <property type="entry name" value="Aldose_epim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016020">
        <property type="entry name" value="PHexose_mutarotase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="SSF74650"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="4">
        <location>
            <position position="166"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="268"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR016020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR016020-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR016020-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV55682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="307" mass="34195" checksum="4600B1F4CB1588EB" modified="2019-10-16" version="1">MIDDLNLQFGIDKKIAFTLGNGDLPKAILLAEDATAEIYLHGAHVSSFHRHGWGEMLWMSDESNFRTDRPIRGGVPICWPWFGQPQPELPQHGFARTSQWEVIETKAHADPSLEIALRLTDSEATRQLWPHPFELTMRVIVGRDLTMQLSCLNTGEEPLDAEAALHTYFHVQDIDAVRVAGLDGRSYIDKLDAMQGKPQAGELTIDREVDRIYLETPDAVTIHDGAERRIEIQKSGSLSTVVWNPWIDKSAAMADFPNDGYRTMVCVETTNAADDVRTIQPGEVHTITQSCRCEPATGPADPAEAIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRH7</accession>
    <name>A0A518IRH7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Phosphoglucosamine mutase</fullName>
            <ecNumber evidence="11">5.4.2.10</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">glmM</name>
        <name evidence="11" type="ORF">Mal33_16710</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the phosphohexose mutase family.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.10" evidence="11"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008966">
        <property type="term" value="F:phosphoglucosamine mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005844">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016055">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I/II/III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005845">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005846">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005843">
        <property type="entry name" value="A-D-PHexomutase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036900">
        <property type="entry name" value="A-D-PHexomutase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016066">
        <property type="entry name" value="A-D-PHexomutase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005841">
        <property type="entry name" value="Alpha-D-phosphohexomutase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024086">
        <property type="entry name" value="GlmM_arc-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02878">
        <property type="entry name" value="PGM_PMM_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02879">
        <property type="entry name" value="PGM_PMM_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02880">
        <property type="entry name" value="PGM_PMM_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00408">
        <property type="entry name" value="PGM_PMM_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00509">
        <property type="entry name" value="PGMPMM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53738">
        <property type="entry name" value="SSF53738"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55957">
        <property type="entry name" value="SSF55957"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03990">
        <property type="entry name" value="Arch_GlmM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00710">
        <property type="entry name" value="PGM_PMM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4 6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PGM_PMM_I" evidence="8">
        <location>
            <begin position="8"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_II" evidence="9">
        <location>
            <begin position="154"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_III" evidence="10">
        <location>
            <begin position="262"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_IV" evidence="7">
        <location>
            <begin position="387"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QDV55692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="449" mass="47013" checksum="53B68F100852B457" modified="2019-10-16" version="1">MSELIISVSGLRGIVGETLTPPVAARYLAAFCNQLTEPGPVVLSYDGRTSGPMLRDLAAAAIVACGRDVLDAGVAATPTVGVLVKQFNAAGAVQISASHNPPAYNGIKLFSAAGRVLDAASGAKVRELYLNDSISWNAADALGSCCAIDDPHASHLDAVLATVDVEAIRKRNFSVVLDSNHGSGSTLGRRLLEALGCRVIVLGDEPNGLFAHPPEPLAENLQGVCETIKSRGCDVGFCQDPDADRLALIDAAGKFIGEEYTVAMCVQRAMMKQPGPIVINLATSSMSQQVAIDAGATPYRSAVGEANVADMMIANAAVYGGEGNGGPIDPAVGYVRDSFVGMAHVLELMATTGKSIAELAAELPRFEIYKAKAEIGREALPAAMDQIAAELPDAEVSRIDGLRLSWSDRWLLVRGSNTEPIVRFIAEAPTLDEAKALCDRAEQIVNACT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRN5</accession>
    <name>A0A518IRN5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_17360</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011453">
        <property type="entry name" value="DUF1559"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07596">
        <property type="entry name" value="SBP_bac_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="335" mass="35978" checksum="01EB772ACE22E1ED" modified="2019-10-16" version="1">MFSKKRVGFTLVELLVVIAIIGILVGLLLPAVQAAREAARRMQCGNNLKQLGLAVHNYADSNREQFPIGTRHEDPANTPVAAAWSGGAHRKGSVLVKILPFVEQAPLYDQLDFVGDIHAQLDALGYNGTSGTRMGVYTCPSDGTTGNTLSGAHQFYNYGKNMGNQVMPGQFGCNIYPDAGGNPAVLGGNMYGSGTTGHGSTNTQANISGVFSRFSWAARFADITDGTANTILFGEIIPSCGDHHRNGWYSTNSLWTATTGPINFNTCGWQQVPNNASNCNDYRVWQTSQAFKSQHPGGAQFALCDGSVRFLPETIDYATYQQLGSRNDGQTVQVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRS9</accession>
    <name>A0A518IRS9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytochrome c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Mal33_17740</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13442">
        <property type="entry name" value="Cytochrome_CBB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome c" evidence="6">
        <location>
            <begin position="177"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV55795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="284" mass="30691" checksum="9C21AE301D0B7866" modified="2019-10-16" version="1">MRWFGWMCVPLMVVSIAIGDEAEDRSANHAADAAKHASGPRQLPPGELGRVIKLGREIVLNTSEHPLSKPYVGNALNCTSCHLDGGEHPQAASFLGIATAYPAWSPREQRVVTLQDRSLNCFMRSQNGTRPPLGSEVSVAITAYITWLSTDQPIRQNPNKPLGPRHVPALDAPDQQPSVSRGAVLYADHCASCHADNGLGSDDGPPVWGDESYNDGAGLSRVPKLASWLKVAMPLDDPYLSTAEAFDIAAFVNSHRRPHFELSKHLPAADARGEYNGVSDEGHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRW1</accession>
    <name>A0A518IRW1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_18150</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021975268" evidence="2">
        <location>
            <begin position="23"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="250"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="260"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="287" mass="28467" checksum="74A11ECD36C02B77" modified="2019-10-16" version="1" precursor="true">MRFLIASMMLVSLIVLSTGCVCGPGGYPLCDSGPGYASGCDSCGPGGCEPSCGFDGGYMEPACGIDGGCGEPSCGCGPAACNSCCINPCAFVCGFLRDIGSCIFGCGGCQSGCGSLYIDEWASCPPACNDPCNNHGDYVGGGGCGCGGGCDGGGGVAPVHGRGLASIWGFKYMGGGSCGGGGCGSGCGCTAGSCGSYASGGSCGSGDCGCQSQSYDVGYSHGGYSQGEIIREQGPSLRPQIMEHQNVPHAVEPPADTLPKPKVSQTSSQHKSGRLVRRSQPTSYIRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IS14</accession>
    <name>A0A518IS14_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_18510</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="125" mass="13950" checksum="A77D1674B8CEFBB8" modified="2019-10-16" version="1">MAKFYVSCGSQTLIISAPTAEFAAMRLMDEAMAAHAWIYDDADLSEQDRRDHLSLEALLHLSSTVRVSECGLGRSDAGEFEVPILLDQWHRLMTGVSRLFVSAGLEPRRVMPANLENVLYPKSPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IS28</accession>
    <name>A0A518IS28_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_18870</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1085"/>
            <end position="1103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1108"/>
            <end position="1127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1139"/>
            <end position="1158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1170"/>
            <end position="1190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="2552"/>
            <end position="2572"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2303"/>
            <end position="2468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="2366"/>
            <end position="2391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="2583" mass="280527" checksum="D5210029EB8924F3" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IS32</accession>
    <name>A0A518IS32_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Na(+)/H(+) antiporter subunit D1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">mnhD1</name>
        <name evidence="4" type="ORF">Mal33_18420</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042773">
        <property type="term" value="P:ATP synthesis coupled electron transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003918">
        <property type="entry name" value="NADH_UbQ_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001750">
        <property type="entry name" value="ND/Mrp_mem"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00361">
        <property type="entry name" value="Proton_antipo_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01437">
        <property type="entry name" value="NUOXDRDTASE4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="31"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="73"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="110"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="133"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="166"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="208"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="239"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="280"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="307"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="338"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="378"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="411"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="461"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="domain" description="Proton_antipo_M" evidence="3">
        <location>
            <begin position="131"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV55863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="493" mass="52542" checksum="430DA83EF13A651B" modified="2019-10-16" version="1">MIAQNLPVLLIVVPLIAAPLCVLIGNRKLVYLLALAVACAVFAMSVGLMAEVVRSGPIHYNIGNWAPPYGIEYVVDGLSGFVLLFVSAIGAVVLLYAPPSVEAEIPASKHYLFYATYLLCLTGLLGICITGDLFNVFVFLEISSLSSYALISLGRTRRAPLAALQYLIMGTVGATFILIGIGLIYQMTGTLNMADIAQRLPVGLQTRTGLVAFAFLTIGLCIKMAVFPLHTWLPGAYTYAPSVVTCFIAATATKVSVYTFIRIVFGIISPQFAFVELPLAKGLMMMAIVGIFAASLAAIYQQDVKRILAFSSIAQVGYMLLGISISNEAGLSAGIVHMFNHAIIKGGLFMVVGCFTLRLGSSQLSDWRGAGRTMPWTALAWTVGGLGLIGVPVTAGFVSKWMLLTAVIDSGAWPVGILMLLSSLLALLYIWRVVETLYFNEPTEIAGQATEPPLRMLIPTYLVVGSTLVFGVWTVYSAGLAQFAAIGLLGGTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IS69</accession>
    <name>A0A518IS69_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GTPase Obg</fullName>
            <ecNumber evidence="5">3.6.5.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">GTP-binding protein Obg</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 9" type="primary">obg</name>
        <name evidence="9" type="ORF">Mal33_19030</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.-" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01898">
        <property type="entry name" value="Obg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.210.12">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01454">
        <property type="entry name" value="GTPase_Obg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014100">
        <property type="entry name" value="GTP-bd_Obg/CgtA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006074">
        <property type="entry name" value="GTP1-OBG_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006169">
        <property type="entry name" value="GTP1_OBG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036726">
        <property type="entry name" value="GTP1_OBG_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045086">
        <property type="entry name" value="OBG_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11702">
        <property type="entry name" value="PTHR11702"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01018">
        <property type="entry name" value="GTP1_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002401">
        <property type="entry name" value="GTP_bd_Obg/CgtA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82051">
        <property type="entry name" value="SSF82051"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02729">
        <property type="entry name" value="Obg_CgtA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00905">
        <property type="entry name" value="GTP1_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51883">
        <property type="entry name" value="OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Obg" evidence="8">
        <location>
            <begin position="1"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="domain" description="OBG-type G" evidence="7">
        <location>
            <begin position="159"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="333"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="165"/>
            <end position="172"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="190"/>
            <end position="194"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="212"/>
            <end position="215"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="282"/>
            <end position="285"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="308"/>
            <end position="310"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV55924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="377" mass="40684" checksum="91C41D03E870A20B" modified="2019-10-16" version="1">MFVDRVEIEVTGGKGGDGCMSFRKEKFVPRGGPDGGDGGGGGSVILVARDGVNNLNDFAGRKFWKAERGSHGSGAKRTGRHGADMVLYVPPGTTIIDAEHGFVIKDMIDIDDTVVVARGGKAGKGNTSFKSATNQAPRERTVGELGEVRNLILELKSIADVGLIGMPNAGKSTLLSRLSQARPEIANYPFTTKHPNLGQVKVDRDRSFILADIPGLIEGAHEGVGLGHEFLRHVERAGILVHLVEPEPSDGTDPVENYRSIRHELTEYTSQLSERPEIVAVTKCELPAADEVCQRMAEVVDQRVHRISAMTGEGLKDLLEAVSAELLKRHQLPTASSNMVAPEEPKPKRVPPHLAGPTSKLSNEVQAHDYVHEEESP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IS81</accession>
    <name>A0A518IS81_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Collagen-binding domain of a collagenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Mal33_18920</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024749">
        <property type="entry name" value="Collagen-bd_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032260">
        <property type="entry name" value="DUF5060"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041437">
        <property type="entry name" value="GH115_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12904">
        <property type="entry name" value="Collagen_bind_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16586">
        <property type="entry name" value="DUF5060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17829">
        <property type="entry name" value="GH115_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022094119" evidence="2">
        <location>
            <begin position="30"/>
            <end position="889"/>
        </location>
    </feature>
    <feature type="domain" description="GH115_C" evidence="5">
        <location>
            <begin position="40"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="domain" description="DUF5060" evidence="4">
        <location>
            <begin position="295"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="domain" description="Collagen_bind_2" evidence="3">
        <location>
            <begin position="801"/>
            <end position="886"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="262"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV55913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="889" mass="97955" checksum="2A94BB075F3D38FC" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISQ8</accession>
    <name>A0A518ISQ8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7 8">Transcription elongation factor GreA</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Transcript cleavage factor GreA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 11" type="primary">greA</name>
        <name evidence="11" type="ORF">Mal33_21100</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7 8">Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the GreA/GreB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070063">
        <property type="term" value="F:RNA polymerase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032784">
        <property type="term" value="P:regulation of DNA-templated transcription, elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00105">
        <property type="entry name" value="GreA_GreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036953">
        <property type="entry name" value="GreA/GreB_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018151">
        <property type="entry name" value="TF_GreA/GreB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006359">
        <property type="entry name" value="Tscrpt_elong_fac_GreA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028624">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001437">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023459">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022691">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036805">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30437">
        <property type="entry name" value="PTHR30437"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01272">
        <property type="entry name" value="GreA_GreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03449">
        <property type="entry name" value="GreA_GreB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006092">
        <property type="entry name" value="GreA_GreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46557">
        <property type="entry name" value="SSF46557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01462">
        <property type="entry name" value="greA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00829">
        <property type="entry name" value="GREAB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="11" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="11" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 7 8" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="GreA_GreB_N" evidence="10">
        <location>
            <begin position="5"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="GreA_GreB" evidence="9">
        <location>
            <begin position="82"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QDV56131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="159" mass="17356" checksum="6A4CDBF2980B653D" modified="2019-10-16" version="1">MSGSVPMTREGYNRLKAEVAHLEGVLMPEITEKLAAAREEGDLKENAEYHAQRENQGLLQAKINELKSKIARADIVDVSQLPKDEVVFGCKVTVKDLTYQDEEEFTLVGVGDDDLDAGKILVTSPIGQGLLGKKVGQTAEISVPAGIQKFEVVKIEHPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISU5</accession>
    <name>A0A518ISU5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_21400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025516">
        <property type="entry name" value="DUF4404"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14357">
        <property type="entry name" value="DUF4404"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="10"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="85" mass="9488" checksum="C8365ADF4EE0121E" modified="2019-10-16" version="1">MPEDQLGQELERLHAMLAAQEELTDEQREKLQQLADDIEAALGKSEASGDFSDQIDELIRDFETNHPTVTDLLRRIVAGLANLGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IT97</accession>
    <name>A0A518IT97_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">UDP-N-acetyl-alpha-D-glucosamine C6 dehydratase</fullName>
            <ecNumber evidence="4">4.2.1.135</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">pglF</name>
        <name evidence="4" type="ORF">Mal33_22900</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the polysaccharide synthase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.135" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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            <end position="47"/>
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            <end position="585"/>
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    </evidence>
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            <dbReference type="Pfam" id="PF02719"/>
        </source>
    </evidence>
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            <dbReference type="EMBL" id="QDV56308.1"/>
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        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
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    <sequence length="648" mass="71156" checksum="EED14311FCBB7363" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
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                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
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                <person name="Bruemmer F."/>
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                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
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                <person name="Kaster A.-K."/>
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                <person name="Rohde M."/>
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    </evidence>
    <sequence length="536" mass="58601" checksum="03758602C587AD72" modified="2019-10-16" version="1"> </sequence>
</entry>
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                <person name="Pinto D."/>
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                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
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                <person name="Jeske O."/>
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                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
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                <person name="Ovreas L."/>
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            <strain evidence="2 3">Mal33</strain>
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    </dbReference>
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            <end position="63"/>
        </location>
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        </source>
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            <dbReference type="EMBL" id="QDV56413.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
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</entry>
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        <name evidence="8" type="primary">sglT_2</name>
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    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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                <person name="Pinto D."/>
                <person name="Vollmers J."/>
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                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.</text>
    </comment>
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        <property type="protein sequence ID" value="QDV56417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038377">
        <property type="entry name" value="Na/Glc_symporter_sf"/>
    </dbReference>
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        <property type="entry name" value="Na/solute_symporter"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00474">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="NA_SOLUT_SYMP_3"/>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
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        <location>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
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        </location>
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    <feature type="transmembrane region" description="Helical" evidence="7">
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        </location>
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    <feature type="transmembrane region" description="Helical" evidence="7">
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
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            <end position="251"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
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        </location>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
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    <feature type="transmembrane region" description="Helical" evidence="7">
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    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
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        </location>
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    <feature type="transmembrane region" description="Helical" evidence="7">
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        </location>
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    <feature type="transmembrane region" description="Helical" evidence="7">
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="643"/>
            <end position="663"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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    </evidence>
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        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV56417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="673" mass="73588" checksum="F0E6B3A10A6BA94E" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITL2</accession>
    <name>A0A518ITL2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_24190</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Planctomycetia</taxon>
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            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="105" mass="11902" checksum="1474B844A3965B9D" modified="2019-10-16" version="1">MDAPSCGEHVLQQQLEVHRTVDKGHGRVEIRVIETSNRFVRHIDWPDFSQAIRLTRTRILGVVRHSEISDAITSVDRERADACDLLKLFDVTGESRTAFTGFATL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITQ1</accession>
    <name>A0A518ITQ1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_24560</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021858748" evidence="1">
        <location>
            <begin position="21"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="76" mass="8067" checksum="495F1F0511B9F85D" modified="2019-10-16" version="1" precursor="true">MLGTCRVAGIGVCLILLSLAGCNGSLETAPATQPVPPPAAELPVANLPVDLREWNWTNRLGIGSCAHASFVYHLRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITZ6</accession>
    <name>A0A518ITZ6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Dienelactone hydrolase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_25540</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002925">
        <property type="entry name" value="Dienelactn_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01738">
        <property type="entry name" value="DLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022083901" evidence="1">
        <location>
            <begin position="21"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="DLH" evidence="2">
        <location>
            <begin position="44"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="262" mass="28394" checksum="193B70E8D7FB7684" modified="2019-10-16" version="1" precursor="true">MRYVFAVLFASLVSLHTATAEVQTKTVQYTDGDVTLEGFVAWDPEKAEADAPGVLVVHQWMGLTDYEKGRCKQLAELGYVAFAADIYGKGIRPANRQDAAKQAGVYKNDRELYRRRLNLGLDQLLKIENVSADKVAAIGYCFGGTGALELARSGAKIGGVVSFHGGLDSPTPADGKNIEAKLLICHGADDPFVPADDIEAFKAELNAADVDWQMVYYSGAVHSFTQPMAGNDNSAGAAYNPRADKRSWNAMRVFFTELFAGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IU05</accession>
    <name>A0A518IU05_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Inosine-uridine preferring nucleoside hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_25320</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016799">
        <property type="term" value="F:hydrolase activity, hydrolyzing N-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.245.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001910">
        <property type="entry name" value="Inosine/uridine_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036452">
        <property type="entry name" value="Ribo_hydro-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01156">
        <property type="entry name" value="IU_nuc_hydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53590">
        <property type="entry name" value="SSF53590"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021757948" evidence="1">
        <location>
            <begin position="28"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="domain" description="IU_nuc_hydro" evidence="2">
        <location>
            <begin position="36"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="349" mass="37659" checksum="185E696C76453F19" modified="2019-10-16" version="1" precursor="true">MMIDRSRSLVLPLMMASLCCLPAVSNADDVKRPVPLIFDTDIGNDVDDVLALGMIHSLQSRGECELLAVTITKDDPMAAPFTDAVNTFYGRGEIPIGVCHSGVTPGTGRFNGLASIKDGDEFRFPHDLRSGKDAPDAVTVLRKALADAEDGSVVIAQVGFSTNLADLLKSKPDDISPLDGMALVKKKVRLLSAMAGAFTKISGSKGPYDHKEYNIIKDIPAAQALATDWPTPILWSGFEIGLAVAYPHESIQQDYGYVPHHPLAEAYIAYNPPPHNRPTWDLTSVLIAVRPGRDYFGLSPRGTVTVADNGLTTFAPAEDGLHQYLTLTDAQKLRVVETLVLLSSEPPKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IU89</accession>
    <name>A0A518IU89_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_26220</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="303" mass="33551" checksum="E5EA799F424630ED" modified="2019-10-16" version="1">MLNKVSVAGYGKTAKTVRSVSMQVKNFYSSIRTSFIAASLLLATLATAQQPQRHRLFNDNMPPGAIGQFRRDLRGPVQCQYQPVKITAEGTAKVSLAIGNMFQADTAEPVYAGFELGNVYRIRITEIPLFEGYEIYPTIELIDRVYPPAGQEVRFAIPIVISNDDMLHALRGNLVTRVIYLEDPSTALPIAETPGEQRDFDIQPHQDALDVADTLGRPVAIIRYGSRTPPSDPTYMNAFLMGCPYWLPLQSPRTEALTPEGQTAAIRTPHIPRDDVPTQVIPSTEQTRIARPYALPIDSGVVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUW5</accession>
    <name>A0A518IUW5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">4-hydroxybenzoate decarboxylase subunit C</fullName>
            <ecNumber evidence="1">4.1.1.61</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_28840</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="4.1.1.61" evidence="1"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018799">
        <property type="term" value="F:4-hydroxybenzoate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002830">
        <property type="entry name" value="UbiD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30108">
        <property type="entry name" value="PTHR30108"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01977">
        <property type="entry name" value="UbiD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="610" mass="66601" checksum="0D7BFD2BE4B52696" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUW7</accession>
    <name>A0A518IUW7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">3-oxoacyl-[acyl-carrier-protein] reductase FabG</fullName>
            <ecNumber evidence="1">1.1.1.100</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">fabG_4</name>
        <name evidence="1" type="ORF">Mal33_28850</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.1.100" evidence="1"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004316">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="267" mass="29045" checksum="7F70CA99B11C1E51" modified="2019-10-16" version="1">MKSIQELFDAQRPVALVTGSGSPRVGNAIAWRLARRGFSIVLHCNTSIDHARKTAAEMTAEGTEVLIVQGAMDDADDVARMFQEIDDRFARIDVLVNSAAIWSPKRLEDVTADDVRKNLEVNTLGTFIAAQAAGLRMVRQSRGGAIVNIGDWAVVRPYVDYAAYFPSKGAIPAMTRSLALELAQRNRFVRVNAILPGPVLLGSEVSDEVEAANRESTLLKRVGTAEHVAHAVEFLIENDFVTGTCLNVDGGRAIYAGDPMQVDHRTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IV56</accession>
    <name>A0A518IV56_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_29730</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="521" mass="57787" checksum="BDD7003B891BAC35" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVI0</accession>
    <name>A0A518IVI0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Proline--tRNA ligase</fullName>
            <ecNumber evidence="7">6.1.1.15</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Prolyl-tRNA synthetase</fullName>
            <shortName evidence="7">ProRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">proS</name>
        <name evidence="9" type="ORF">Mal33_30970</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>ATP + L-proline + tRNA(Pro) = AMP + diphosphate + L-prolyl-tRNA(Pro)</text>
            <dbReference type="Rhea" id="RHEA:14305"/>
            <dbReference type="Rhea" id="RHEA-COMP:9700"/>
            <dbReference type="Rhea" id="RHEA-COMP:9702"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78532"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.15"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="7">Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.15" evidence="7"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004827">
        <property type="term" value="F:proline-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006433">
        <property type="term" value="P:prolyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00778">
        <property type="entry name" value="ProRS_core_arch_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01571">
        <property type="entry name" value="Pro_tRNA_synth_type3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004499">
        <property type="entry name" value="Pro-tRNA-ligase_IIa_arc-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016061">
        <property type="entry name" value="Pro-tRNA_ligase_II_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017449">
        <property type="entry name" value="Pro-tRNA_synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033721">
        <property type="entry name" value="ProRS_core_arch_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43382">
        <property type="entry name" value="PTHR43382"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09180">
        <property type="entry name" value="ProRS-C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00946">
        <property type="entry name" value="ProRS-C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64586">
        <property type="entry name" value="SSF64586"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00408">
        <property type="entry name" value="proS_fam_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 7 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="8">
        <location>
            <begin position="46"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV57096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="504" mass="57331" checksum="B64EC001E3322B42" modified="2019-10-16" version="1">MNKAPKTAITPTRVDDYPEWFQQVIKAADLAEVSPVRGCMVIKPWGYALWENMQRVLDDMFKATGHQNAYFPLFIPMSFLEKEAEHVEGFAKECAVVTHHRLEPDGKGGLQPAGPLEEPLIVRPTSETIIGSMYAKWVQSYRDLPILINQWANVVRWELRTRLFLRTAEFLWQEGHTVHATSEEALEETRKMIDVYADFAENWMAMPVIQGEKTPAERFPGAVSTLSIESMMQDRKALQAGTSHFLGQNFSKAQEIQFQDQDGNMQFAWTTSWGVSTRLVGALIMTHSDDDGLVLPPKLAPSHIVILPIYRDDEQRAAVLEYVGKLREELSAQYYSGRRISIEVDDRDIRGGEKKWYHVKRGVPLRLEVGPKDIDKNAVFVGRRDTGETKSMDRDQLVADVIGMLDSIQTNLFDRALKMREENTCEIDNVDDFRAYFTAKNPDRPEIHGGFASCYFSNEDDLEPLLKELKVTIRCVPLKDNDTPGTCFMTGKPAEKKAIFAKAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVR3</accession>
    <name>A0A518IVR3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Macrolide export protein MacA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">macA_3</name>
        <name evidence="3" type="ORF">Mal33_31680</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="220"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="domain" description="HlyD_D23" evidence="2">
        <location>
            <begin position="254"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="479" mass="52316" checksum="7CE87541E4CDA885" modified="2019-10-16" version="1">MPSTADTQPNLPHSGHLPTVAEAAPSFAGEAHALAAALELLIQLEEFDDLALAAAVASDAIGDFCHARRVVVGWCRGDRQTCDVIADSEADLIDANNPTFRKLQFALDELVVRGTVTEIDLSTTEAPPAAALAVRQFASAAGATRILGSPLVDADGRLCGAWLFVDPAVQIEALRTTHLIDSLSRPLGARLATIQRHQPGRIDRAIAVVRDAFASSRGSVAIAALIVLIFVMLFPIHYSVRCDCALQPVSRRLIAAPFDGSLEKSFVDPGDLVDENTLLARISARELNWELAGLKAELHRSNKERQVSLAKQDYAASQIAQLDSQQVAHRLQLIEDRIEHLEIRSPFQGIVIAGDIKQVEGAPLETGQTLFEIAPLGAMIVELRIPEADYAYVRPQMPVQLRLHAFPTQPIEGRVENVHPKAEVIDNANVFVAKIQIDDPHAIYRPGMHGRASIRSDRRPLVWVLFHKPWSALMMWLGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVT2</accession>
    <name>A0A518IVT2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Putative nickel insertion protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_32000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the LarC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016151">
        <property type="term" value="F:nickel cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01074">
        <property type="entry name" value="LarC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002822">
        <property type="entry name" value="Ni_insertion"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36566">
        <property type="entry name" value="PTHR36566"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01969">
        <property type="entry name" value="DUF111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00299">
        <property type="entry name" value="TIGR00299"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="1 2" id="KW-0533">Nickel</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="402" mass="42404" checksum="76ECFEFD2EDB12C0" modified="2019-10-16" version="1">MRIAYFDCTSGISGDMTLGALIDAGASIDRIQAGVRSMGLGEISITAENIKKYGFRATQVTIAHPPEHAHRHLHHIEAMLDKGDISAEARDLAKLIFRNLGEAEAQVHGSTLEKVHFHEVGAIDSIADITGVAIALTELGIERVEASPVPTGGGTIQIAHGRVGVPAPATALLLAGIPIAPSDIQAELTTPTGAAILKTTCKAFGPIPAMQISAIGCGSGTMDLEKQANILRVLIGDSDGQPAAEQAAGQFETDQIVITETNVDDSTAEELAWCVDQLFDAGALDVYQTPTMMKKGRSGTKITVLAAPDRTATIESVLLGCSSAIGVRSWAARRTKLIRRAHAVETSFGSVQGKCVWLPSSQWRFTPEHESLRQLAAEKQVSLHAVRDAAVKAFDASDLAAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVU2</accession>
    <name>A0A518IVU2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_31970</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011465">
        <property type="entry name" value="DUF1571"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07608">
        <property type="entry name" value="DUF1571"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021895534" evidence="1">
        <location>
            <begin position="30"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="301" mass="33955" checksum="D2AABA2D37EF32B9" modified="2019-10-16" version="1" precursor="true">MRRQSRQQETSTTMIALLLICLLPTLATAEESASLGTAPAKKAAAAPTSAHPLDRVIEIATKGLQRTDEEVKEYSCLLIKRERIDGELTARQYMQAKVRHRHFADGKLVTPMSVYLKFLKPSELAGREVLYVEGERDGNVLARRGGPRLANITVELNPKGHWAMQGNLHPITEFGFRNLIFRLLEKMRSDLASSDIDVKFYDNAKLGDRECEHIQVTQTNRSATADYHIARIFIDKELQVPVYFASYDWPEADGEPPLKEEYIFANVDLNPNFVAMDFDADNPDYAFEPIASQESLAQVEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWA6</accession>
    <name>A0A518IWA6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA polymerase sigma factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpoE_4</name>
        <name evidence="5" type="ORF">Mal33_33740</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000838">
        <property type="entry name" value="RNA_pol_sigma70_ECF_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01063">
        <property type="entry name" value="SIGMA70_ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="3">
        <location>
            <begin position="31"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="4">
        <location>
            <begin position="130"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV57369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="198" mass="23027" checksum="0DDF5F46329C1858" modified="2019-10-16" version="1">MTDPTPSNDAHLEDAIRRTRDGDKAAFETVIRRFEKPLRSWLAGHVPPGIDVDEVAQRTFVAAYCRLSDYQPGTQFAAWLFTIARFQLRTETTRLRRIADYHSRYGPDLLQRELDRRSEEAPQRWDTRLDSLHLCLDALSEPLRRFVDWRYEEEIPLEEMAARCGRSVAAVKKQLWKARQALQQCVETRLARADGGLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWF7</accession>
    <name>A0A518IWF7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_33950</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="138" mass="13927" checksum="560F8770DDD4FE6C" modified="2019-10-16" version="1">MLKVRMLLWVGFAATVLGCGGGGVPVHPVTGTITVDGTPTAGIGVTLVSEGSAAMGLTGVTDDQGAFEIVAAGGYQGAPTGTYKVLLSAPRAEVDYSSNKAPVEVQFPPQYSNPNSAELTTVEVGDGDSVVTIDVKTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWJ5</accession>
    <name>A0A518IWJ5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_34570</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029475">
        <property type="entry name" value="PmoA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14100">
        <property type="entry name" value="PmoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022001031" evidence="2">
        <location>
            <begin position="26"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="205"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="337" mass="37095" checksum="6C49888FE3AC9106" modified="2019-10-16" version="1" precursor="true">MTLTTRSLLSSLLAAWCLLASPIAAAELQMTETDAAIEIASDGKSVLVYNKQSPPVPDGIDPIYHRSGFLHPVASPAGNVVTAAFPADHPHQQGIFSAWVRTNYDGREIDFWNLAGGVGRVSHERVVKTFTENESAGFEVDLIHHTVAEPKVDILRERWRITVQPTDGSYRCFDLQTTQQALTDKPLTVAKYHYGGVATRGPARWSLPSGKKAAAKASDADNNEPSEPISEIVDEHGHDRIAGNHHPTRWVTLSGTEGDDLVCITMLGHADNFRAPQPARLHPSMPYFCFAPCVTGEFQIAKDQPYEASFRFLVTDGKPDPAWIEQQWQAWCGDKAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWM1</accession>
    <name>A0A518IWM1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cardiolipin synthase</fullName>
            <ecNumber evidence="9">2.7.8.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">cls</name>
        <name evidence="9" type="ORF">Mal33_34980</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.8.-" evidence="9"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008808">
        <property type="term" value="F:cardiolipin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032049">
        <property type="term" value="P:cardiolipin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022924">
        <property type="entry name" value="Cardiolipin_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025202">
        <property type="entry name" value="PLD-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001736">
        <property type="entry name" value="PLipase_D/transphosphatidylase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13091">
        <property type="entry name" value="PLDc_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00155">
        <property type="entry name" value="PLDc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04265">
        <property type="entry name" value="bac_cardiolipin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50035">
        <property type="entry name" value="PLD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="37"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="domain" description="PLD phosphodiesterase" evidence="8">
        <location>
            <begin position="220"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="PLD phosphodiesterase" evidence="8">
        <location>
            <begin position="400"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV57488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="487" mass="54023" checksum="8AE9557BA291A4B2" modified="2019-10-16" version="1">MIHPGALSIALSVLHLLVAIAISFRVIMRKPPVGVALAWLFLVAAVPLAGVGFYLLVGERRVGQRRARKIARLRIDYERLAELAITEGLTDVDWTTHRREAAAMDRLGVSQVGVPTVSGSRVELLKDADSILRGIADDIDQARNSVLMEFYIWNQGGGAELVFEALKRAAQRGVSCRLLVDSVGGRPWWKGPQPAELRKAGVLCRPALKAGLWRTIFARNDLRLHRKIVVVDGEVAWTGSMNLVDPKFFKQDADVGQWVDAMLRLQGAAVSPLAMTMIGDWMLETDESVDEIIRCAELRMVEREGTGDIQVIPSGPSETDDGLLQMLLALINSAHDELVLTTPYFVPDDSMVRAIRGAAGRGVKVHLVVPNRVDSTLTHFASRSYYDELLEVGVQIYLYDQGLLHTKSVTADGDMAMFGTVNLDMRSLWLNYEVSLFLYGQDLTGPVRELQGSYIDASKRLDPAEWTNRSLRERFLENVLRLIGPVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXA3</accession>
    <name>A0A518IXA3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Peptidase family C25</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_37350</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008234">
        <property type="term" value="F:cysteine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029030">
        <property type="entry name" value="Caspase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001769">
        <property type="entry name" value="Gingipain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029031">
        <property type="entry name" value="Gingipain_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01364">
        <property type="entry name" value="Peptidase_C25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52129">
        <property type="entry name" value="SSF52129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021810018" evidence="2">
        <location>
            <begin position="21"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_C25" evidence="3">
        <location>
            <begin position="24"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV57722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="532" mass="56933" checksum="90486C97968DF53B" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXA7</accession>
    <name>A0A518IXA7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_37360</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Rosistilla</taxon>
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    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021474">
        <property type="entry name" value="DUF3127"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11325">
        <property type="entry name" value="DUF3127"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="126" mass="13783" checksum="52C513BC48952203" modified="2019-10-16" version="1">MSEAKVKGIVHLVEETKTYGAKGFRKRMVVLSQDFGSFTNYVPLEFTRDNCELANDLNVGDEIEVNYRLNGRKWQKDANSEVKYFLSAEAMGFKAVGSAPPAGGGNAASANDAFSEVSYDEGDVPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXF2</accession>
    <name>A0A518IXF2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">GIY-YIG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_37810</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000305">
        <property type="entry name" value="GIY-YIG_endonuc"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50164">
        <property type="entry name" value="GIY_YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GIY-YIG" evidence="1">
        <location>
            <begin position="2"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="267" mass="30342" checksum="68214901BAD07101" modified="2019-10-16" version="1">MNDYYVYVYIDPRNLQEFYFGKGRGSRKNAHLSDTSDSEKAKRIAAIKAAGLEPTIRVIARDLSEHDALLIEKTLLWKLGRHLTNQATGHYAKNFRPHDTLHVELDGFDYQRGIYYYNVGEGPCRDWDDYRQYGFISAGQGLSWRNAITGFNVGDIAVAYLKGRGFVGIAEILTKATRIANVEIDGVPMSDLDLTCQNMFSNSDSEDRSEYVCAVKWLRAVDRNGAHWKPKSGLYTTTHVRASLDGQPKTIEYIETCFDIDLREYAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXM1</accession>
    <name>A0A518IXM1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PTS system fructose-specific EIIABC component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">fruA</name>
        <name evidence="2" type="ORF">Mal33_38500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041657">
        <property type="entry name" value="HTH_17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016152">
        <property type="entry name" value="PTrfase/Anion_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002178">
        <property type="entry name" value="PTS_EIIA_type-2_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12728">
        <property type="entry name" value="HTH_17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00359">
        <property type="entry name" value="PTS_EIIA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55804">
        <property type="entry name" value="SSF55804"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51094">
        <property type="entry name" value="PTS_EIIA_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PTS EIIA type-2" evidence="1">
        <location>
            <begin position="84"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="235" mass="25825" checksum="554F5A2C713E68A5" modified="2019-10-16" version="1">MSEENFDVAGLAAYLHLTPDQVNKMAQRGRLPGRRVSGGWIFSEAEVHHWLEQQIGASDLEQLDKVDAVLSRADNIDNDITIASFCSLDVVEVPLQARTKGSVIRSMSALAARGGMLWDPAAMAEAVKAREELHPTALDCGVALLHPRRPQTSILADSVVALGRTSQPLPFSDTGQLTDVFFLLASYDDRVHLRILSRISRMITDEIFLGQLREAPDAASARQAILDVEERIDEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXS0</accession>
    <name>A0A518IXS0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_39050</name>
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    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
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    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13673">
        <property type="entry name" value="Acetyltransf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="33"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="172" mass="19268" checksum="99AD203BAD865340" modified="2019-10-16" version="1">MSNVWGIEPFERKKHVRTGFDCGVAVLNDWLATKISQYEKRDLARTYVLVGDGGNAVKGYYALSNHTVVYEALAKDQARGLPQIDLPVVLIGRLAVDTTVRGQGLGEFLLLDALRRVEYLAAKIGIQAVEVDAINDRAKQFYLKYGFTPLQDNPSHLFLPMQVVRKLRLPPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXT7</accession>
    <name>A0A518IXT7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Type II secretion system core protein G</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">xcpT_11</name>
        <name evidence="13" type="ORF">Mal33_39150</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the GSP G family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015627">
        <property type="term" value="C:type II protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015628">
        <property type="term" value="P:protein secretion by the type II secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000983">
        <property type="entry name" value="Bac_GSPG_pilin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013545">
        <property type="entry name" value="T2SS_protein-GspG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010054">
        <property type="entry name" value="Type2_sec_GspG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08334">
        <property type="entry name" value="T2SSG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00813">
        <property type="entry name" value="BCTERIALGSPG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01710">
        <property type="entry name" value="typeII_sec_gspG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="domain" description="T2SSG" evidence="12">
        <location>
            <begin position="36"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="74"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="117"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="77"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF08334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="QDV57899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="139" mass="15178" checksum="434536FDC4FAF1E8" modified="2019-10-16" version="1">MRKQRSRRRAAFTLLEVLLVLIILVIIGGIVTVNFVGIQKGAQDDTARTQLNNIKSGIKLYQLQVGTLPSSLEGLREKPNDIADPTRWKGPYFDEDIPADPWGNDYKYAPSGTGFELRSAGADGQEGSEDDVVVTSGTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXV3</accession>
    <name>A0A518IXV3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_39310</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="104"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="153"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="182"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="224" mass="25117" checksum="5E0121C9C189F810" modified="2019-10-16" version="1">MDWLLEPARMQFCERTLDGPIKHPADTWTNIGPLVAGIFILIYANRPLERLLGVAAIWTGLASGYFHASNTILGETLDLSGMFMFILSIAALQQHRSDPNQPGQRMLIAIVLVGSLILTVLSSFSTAFASPMFAVIVVIVVARGLYDSMLTRWAYAMVITFLIAWGFWWLDFMHIVCHPDNHILTGHGLWHLLNGVVFWCAFRHYQSTMPDPATELAEDQQQGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXX3</accession>
    <name>A0A518IXX3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">F0F1-ATPase subunit (ATPase_gene1)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_39500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032820">
        <property type="entry name" value="ATPase_put"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09527">
        <property type="entry name" value="ATPase_gene1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="74" mass="8075" checksum="36E2EED2F21BCA5B" modified="2019-10-16" version="1">MQTLAGSDDDKPSYLRFAGAGLELAGAMFVPATIGYLIDSHFMWQTPWGFLIGGILGFSAGMYNFIRLANKLNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXZ0</accession>
    <name>A0A518IXZ0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH cro/C1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_39620</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="56"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="121" mass="13473" checksum="FC3A8828BE16F700" modified="2019-10-16" version="1">MNPSNDKTVGGELLERLGKFTKALEHTNSSADLPAILTVRKVKSSLSPHVYSGQQIKAIRLQLRVSQPVFADYLGLSVATLRDWEQGISQATGPMCRLLEEIERDVPLWAKRLREMAEVGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IY08</accession>
    <name>A0A518IY08_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Mannonate dehydratase</fullName>
            <ecNumber evidence="7">4.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">uxuA</name>
        <name evidence="8" type="ORF">Mal33_39830</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the dehydration of D-mannonate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>D-mannonate = 2-dehydro-3-deoxy-D-gluconate + H2O</text>
            <dbReference type="Rhea" id="RHEA:20097"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17767"/>
            <dbReference type="ChEBI" id="CHEBI:57990"/>
            <dbReference type="EC" id="4.2.1.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5">Carbohydrate metabolism; pentose and glucuronate interconversion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the mannonate dehydratase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.8" evidence="7"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00246"/>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008927">
        <property type="term" value="F:mannonate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006064">
        <property type="term" value="P:glucuronate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004628">
        <property type="entry name" value="Man_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30387">
        <property type="entry name" value="PTHR30387"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03786">
        <property type="entry name" value="UxuA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016049">
        <property type="entry name" value="Man_dehyd"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="SSF51658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00002713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00007389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00012927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV57967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="321" mass="35127" checksum="A8AC94F616EDE54E" modified="2019-10-16" version="1">MQLSSVVTPFDDENLARVAQLGVSAVAIRYPGLELRDLLETRERLSRHGLKIAAIEGELPIQNAILGTANQADDFSSMKQLLAIMGEAGVPICCYNFMPATDWARTDTKVRERGGSLTTAFRSSDAESAASLHSISQSDSISPISSDQLWSNLQRFLEELLPAAEAAGVALAMHPDDPPLASFGKHARIMNRLEDFDRLLEISASPSNGICFCQGNFAAMGVDIPDTIRRWGEGIRYVHFRDVQGTADNFIETFHDNGPTDMVAAMKAYRDIGFTGPIRPDHVPQLAGEEQGQPGYTMLARYFAYGYIRALIQATELPADC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IY14</accession>
    <name>A0A518IY14_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_39930</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032307">
        <property type="entry name" value="PepSY_TM-like_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40115">
        <property type="entry name" value="PTHR40115"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16357">
        <property type="entry name" value="PepSY_TM_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="183"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="318"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="350"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="371" mass="42075" checksum="1BBE627E544B2359" modified="2019-10-16" version="1">MGFLPRRWRKFHRRRSIDRRRALAKENAREILAEDHEFPTSPVANQAGGNYAYCDAISITRRLSRQQTVCNRLFPPANGNASTIICRIWAPIDAKHFCLVASIQRQRRARRFVLQTQGYQYAIFNAYRTVRLAKCVDVARSHHGESGLNNRPSDTTTPPIESDLPSVSQTLRRGFWLRTMIQWHWISSAVCLVGMILFSVTGITLNHASQIETVPDVEHKIIELPQEITDAIDAQTPAEKAPLPPAVATWLSEQTGIAIGSRDAEWSEDEIYLSMPGPGSDAWVSIDRFAGEVEFERTQRGWISYFNDLHKGRNTGPAWSWFIDIFAIATLVFCFTGLGLLFLHARNRRMTWPLVGLGLIVPFLLALLLIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IY94</accession>
    <name>A0A518IY94_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_40800</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011444">
        <property type="entry name" value="DUF1549"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022655">
        <property type="entry name" value="DUF1553"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07583">
        <property type="entry name" value="PSCyt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07587">
        <property type="entry name" value="PSD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021798770" evidence="1">
        <location>
            <begin position="22"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="domain" description="PSCyt2" evidence="2">
        <location>
            <begin position="338"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="domain" description="PSD1" evidence="3">
        <location>
            <begin position="567"/>
            <end position="792"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV58063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="821" mass="90827" checksum="298AB334CC5E183E" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYC3</accession>
    <name>A0A518IYC3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">WD domain, G-beta repeat</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_41080</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="SSF50978"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022154948" evidence="2">
        <location>
            <begin position="21"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="83"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="291"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="350" mass="37716" checksum="E2CEF5FB2850E90C" modified="2019-10-16" version="1" precursor="true">MVFRFAFILLSLAMACFELANCHAIETIPNNLSIRLEPVAGRDYPPVVTALAISPGGELLAAAGDDHAIRLLSGENFSKQQIIGQHTDWVRSLDFAPDGSMLLSAGNDGRIQVWLRESNWENPRDIGGGPALACVRFNDDGKRIAAVGFDPQIFLMQSKTIPAAKLTCKCRDLRTALFTDVDDILAVGGRSGEMHFIDPDTGETLAAISLHVGRLRDSTLVRGANMIVSVGEDGRCAIVDTVQMKMLREVTIPGCKLLSVAAIDSQHVAVGGSDNLIRVLNVNSGEVTKKLTGHQGTVAVLKANVEHLISGSYDTSIRFWRLSQIQQHETVAGIPGMESTDTTSTLATER</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYH5</accession>
    <name>A0A518IYH5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Esterase PHB depolymerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_41580</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010126">
        <property type="entry name" value="Esterase_phb"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10503">
        <property type="entry name" value="Esterase_PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="339" mass="37006" checksum="F567328201AB81A0" modified="2019-10-16" version="1">MKRMLRFAIIGAALVVVAIGGIASYAQFRLLAAQTGVNVTFEHQGQTREYRLHVPEGLESGEPVPLLVFLHGGGGNARVASVMGFSKLADREKFIVVYPNAIDKHWNDGRDSPMFADQDREVDDVDFIMQVVDRVCQKHPIDANRIFAAGVSNGGFMTQRLAMEKPETFSAVAVCIATMGEAISKRFDPALPVSVLYLNGTEDLLVPYDGGPVGKGLGPRLNRVEGNPIAPRGRAIGTDDAVELWVDRNKTAAEPTVKKLADKNQEDGSHIEYYQWAGGQRGTVVGLYKVVGGGHTLPGSRQYYPVKVIGRPNQDAQGTELVWDFLIQHPRQPKPSSTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYR0</accession>
    <name>A0A518IYR0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_42400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="368" mass="41633" checksum="7DDDC404EC2F1842" modified="2019-10-16" version="1">MSLDTAIAEAKATLDAHTHEIVQWHFHESTGSPFWLQKKSELKFDPLTEVKCFDDLKKFPLFEDDWLRGGPVRRWVPKGYENEPVYVFETGGTTGVPKSRVVMRDHWIDYEMFSDTLPEEHFPKGANWLMLGPSGPRRLRLAVEHLAQHRGGICFCVDLDPRWVVKLIKKGWMEHLEEYKKHCIDQAITILTAGHDIQCMFTTPKLLESLGDALEERGSSIQEMGIKGIFSGGTEFTPQWTRYAVEELLGGSPEEGGVYMTPTYGNTLMGLACSKPITAAEQYKISYYAPQPRAATEVVEFEDHTQVVSMGGTGRVKLYTLTKEFFVPGFLERDEGEREAPFDKFPWDGVSGVRPFHELASATTVGVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYS5</accession>
    <name>A0A518IYS5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_42520</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="216" mass="24035" checksum="3AD0C23D18A4E0F1" modified="2019-10-16" version="1">MRRLQESVALSPLLVELGIVVAQRGSHFFLEFDYGGTAIPLARITPMKESPAFALESEGDSGWVLYGQGTPSRIVKLLCNDTLGTFHALGGIDQVLRNSAKKVPEVVQKTPRTFAYKRTNAPCSLQEALYFHFGIPLVVAMEPREYYRQHAEPSLLETSDDQHQVLIRFCSRNPANPRILGHGYYRLLGGDWYGIGVPPEVANTLDEAEAYLKSTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ00</accession>
    <name>A0A518IZ00_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SGNH_hydro domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_43340</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021720087" description="SGNH_hydro domain-containing protein" evidence="1">
        <location>
            <begin position="32"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="domain" description="SGNH_hydro" evidence="2">
        <location>
            <begin position="69"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="438" mass="47917" checksum="93D97A1C06522F3A" modified="2019-10-16" version="1" precursor="true">MTNRNLKTCWRGIAALAICAATMMPQIPAIAADAPEYAPVAAELVRPRGGMGNVLEKLRAGEPVKIAYLGGSITAAAGWRVKTREWFSEQFPQAKVEEIHAAIGGTGSDLGVFRVGRDALQHKPDLMFVEFAVNDGGAAPEQIWKAMEGIVRQTWAANPRTDICFVYTFRTGYENDLGKGMCPRAASAMEMLADHYQVPSINVALKIVELQQAGKLIYKSDQPTEAGIVRFSSDGVHPLDDGHQIYTDVIADAVEQIGKASTPVDHGTKLDKPFVEDHWQAAKMVPLTAEMLSPQWQQLPADSTLAKRFGNRMGTIWEATQPGSKLTFKFRGSIAKLYDLLGPDGGQVLISVDGKPRPKPVPRFDSYCTYHRIATLSVANGLDPNEVHTVTVEVDSQQPDRQSVAFRLKDPETELKQPKYQGTNVRVGQILVLGDVIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ18</accession>
    <name>A0A518IZ18_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_43450</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010869">
        <property type="entry name" value="DUF1501"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07394">
        <property type="entry name" value="DUF1501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="484" mass="53410" checksum="8A1F15A7BC2BBF21" modified="2019-10-16" version="1">MTNLPNIDSVSARRHFMASSAMSVGSLAMAWMNQQEAKANPQQPNLEPLSFDTLPKQPHHPPKAKAMISLWMQGGPSHHDMFDPKPEMVKHDGEDFPDEIKYDDAANASSKIFASPWKFSPQGECGMELSELIPHTGSIADEICLIRSTKTGVNNHGQSIRALQTGRITAGRPSLGSWLTYGLGSEADNLPAFLALIDPGQLPVMGVENWSNGWLPSVYQGTVIRPTEPRILDLTPPAHLKGKAQARALEFLEQLNEQHRAQRPGQHDLQARIASYQLAAKMQVAATDAMDLSQESRATQEMYGMHEKETADYGSRCLIARRLIERGVRFVQVYTANQLWDSHGGIIKGLPAACRKVDRPSAALVRDLKQRGLLDSTVVHWGGEMGRLPVVQNDAGRAKYGRDHNTHGFSMWVAGGGFKAGHVHGKTDEWGHKAIEDVVNHFDYHATLLHLFGLDHEQLTFHRANRDQTLTDGQPGQVIPGLLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ23</accession>
    <name>A0A518IZ23_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">L-threonine aldolase</fullName>
            <ecNumber evidence="3">4.1.2.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ltaE</name>
        <name evidence="5" type="ORF">Mal33_43470</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>L-allo-threonine = acetaldehyde + glycine</text>
            <dbReference type="Rhea" id="RHEA:26209"/>
            <dbReference type="ChEBI" id="CHEBI:15343"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:58585"/>
            <dbReference type="EC" id="4.1.2.48"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>L-threonine = acetaldehyde + glycine</text>
            <dbReference type="Rhea" id="RHEA:19625"/>
            <dbReference type="ChEBI" id="CHEBI:15343"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="EC" id="4.1.2.48"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 3">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the threonine aldolase family.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.48" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008732">
        <property type="term" value="F:L-allo-threonine aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006567">
        <property type="term" value="P:threonine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001597">
        <property type="entry name" value="ArAA_b-elim_lyase/Thr_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026273">
        <property type="entry name" value="Low_specificity_L-TA_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01212">
        <property type="entry name" value="Beta_elim_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038940">
        <property type="entry name" value="Low_specificity_LTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0456">Lyase</keyword>
    <keyword evidence="2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta_elim_lyase" evidence="4">
        <location>
            <begin position="9"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR038940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV58329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="350" mass="38644" checksum="CA29246A493E78D2" modified="2019-10-16" version="1">MNAIEPGFQFASDNTSGVCPEAWNAMLEANSGYAASYGDDPWTKRARDLVREIFEFDCHVYFIFNGTAANSLALASMCQSYHSVLAHQLAHVETDECGGPEFFSNGTKLLLVEGEGGRVDPAAVEKVVRRRSDVHFPKPKVLSITQATEMGTVYRGEDLDRIYETARRLHLNLHMDGSRFANALATLNVSPKELTWKAGVDVLCLGGTKNGMAVGDCVVFFDDDLAYEFEYRCKQAGQLASKMRYLSAPWVGLLESGVWLKNAQHANAMARLFAERLQAFPGVSVRNNVESNAVFLQFPPAVAAALRSAGWHFHDFIGVGESRLMCSWNTTEQEIEAFLKSLADAIKQNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ38</accession>
    <name>A0A518IZ38_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_43700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="140"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="163"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="196"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="239"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="288" mass="31708" checksum="316249552BDD5358" modified="2019-10-16" version="1">MSNGELIHPRIGPLSILGAITILVLQVVFGMWVLFYYGSPFGQAAWIGLMWLGCSMTASVCFSATFSWRRVLFGGLSFLWHVLFMAICWRETPLRYMLLLGGLLVLQGTFSTILGVPAWHWGRESKAALPTRYRFTIRSILVATTVVAMLLSAARAYELPMVAPQLLAVPLFVLLYLGAASAMLAESHVRIRALCLLAVLLGGSLLYSWIATALVGSTGQSLTLRQFVGSLGSNSLDGFVVQMQMVQFGLFTIGCCLCFGFGRTDDRDFVRRQLWRQESDSAKSTQAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ47</accession>
    <name>A0A518IZ47_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 12">Methenyltetrahydromethanopterin cyclohydrolase</fullName>
            <ecNumber evidence="6 12">3.5.4.27</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11 12">Methenyl-H4MPT cyclohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12 13" type="primary">mch</name>
        <name evidence="13" type="ORF">Mal33_43780</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 12">Catalyzes the hydrolysis of methenyl-H(4)MPT(+) to 5-formyl-H(4)MPT.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>5,10-methenyl-5,6,7,8-tetrahydromethanopterin + H2O = H(+) + N(5)-formyl-5,6,7,8-tetrahydromethanopterin</text>
            <dbReference type="Rhea" id="RHEA:19053"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58018"/>
            <dbReference type="ChEBI" id="CHEBI:58337"/>
            <dbReference type="EC" id="3.5.4.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4 12">One-carbon metabolism; formaldehyde degradation; formate from formaldehyde (H(4)MPT route): step 3/5.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 12">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 12">Belongs to the MCH family.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.27" evidence="6 12"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00562">
        <property type="reaction ID" value="UER00703"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018759">
        <property type="term" value="F:methenyltetrahydromethanopterin cyclohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046294">
        <property type="term" value="P:formaldehyde catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00486">
        <property type="entry name" value="McH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003209">
        <property type="entry name" value="METHMP_CycHdrlase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02289">
        <property type="entry name" value="MCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03120">
        <property type="entry name" value="one_C_mch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10 12 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 12" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00006902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00020597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="QDV58360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="316" mass="33006" checksum="6B51CC50C949FFE7" modified="2019-10-16" version="1">MTQFNQAAFQTANDLEENLAEYRVGSTTIGGATLFDLGIEHRGGLVAGEMLADVCLGAAADVFAAAEPGAIGTGVVVKVATDNPVGACLACQYAGWPLSVGDYSAMVSGPIRLLRGKEQLLEKLGLSESGAIGVAVLEADTYPTEAAVLKIAEECSIEPELLTILIAPTTSIAGNIQVVARSVETAMHKLHEVGFDVNDVLSATGSAPLPPPALKSIDGIGRTNDAILYGGSVTLFVDADQAVIDEIGPKVPSNSSSDYGKTFGEIFASYEYDFFKVDPHLFSPAVVTFVNLRSGISRTFGQLRPDILEASFGCKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ63</accession>
    <name>A0A518IZ63_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ribosomal RNA large subunit methyltransferase K/L</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rlmL</name>
        <name evidence="7" type="ORF">Mal33_43940</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008990">
        <property type="term" value="F:rRNA (guanine-N2-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017244">
        <property type="entry name" value="23SrRNA_methyltr_KL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000241">
        <property type="entry name" value="RNA_methylase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019614">
        <property type="entry name" value="SAM-dep_methyl-trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004114">
        <property type="entry name" value="THUMP_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10672">
        <property type="entry name" value="Methyltrans_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02926">
        <property type="entry name" value="THUMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01170">
        <property type="entry name" value="UPF0020"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037618">
        <property type="entry name" value="RNA_Mtase_bacteria_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51165">
        <property type="entry name" value="THUMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01261">
        <property type="entry name" value="UPF0020"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="THUMP" evidence="6">
        <location>
            <begin position="98"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="423"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="427"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV58376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="803" mass="90302" checksum="642A93458972AAC9" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZE4</accession>
    <name>A0A518IZE4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Filament cap protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Flagellar cap protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">fliD</name>
        <name evidence="9" type="ORF">Mal33_44800</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Homopentamer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the FliD family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009421">
        <property type="term" value="C:bacterial-type flagellum filament cap"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009424">
        <property type="term" value="C:bacterial-type flagellum hook"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007155">
        <property type="term" value="P:cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040026">
        <property type="entry name" value="FliD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010809">
        <property type="entry name" value="FliD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003481">
        <property type="entry name" value="FliD_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30288">
        <property type="entry name" value="PTHR30288"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07195">
        <property type="entry name" value="FliD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02465">
        <property type="entry name" value="FliD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="9" id="KW-0966">Cell projection</keyword>
    <keyword evidence="9" id="KW-0969">Cilium</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9" id="KW-0282">Flagellum</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FliD_N" evidence="7">
        <location>
            <begin position="12"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="FliD_C" evidence="8">
        <location>
            <begin position="775"/>
            <end position="1000"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00033074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00033192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV58457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1014" mass="103793" checksum="515BF08316786CEA" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZK8</accession>
    <name>A0A518IZK8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Multidrug resistance protein MdtN</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">mdtN_2</name>
        <name evidence="4" type="ORF">Mal33_45490</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039562">
        <property type="entry name" value="MFP_biotin_lipoyl_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13533">
        <property type="entry name" value="Biotin_lipoyl_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Biotin_lipoyl_2" evidence="2">
        <location>
            <begin position="47"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="HlyD_D23" evidence="3">
        <location>
            <begin position="222"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="86"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV58526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="421" mass="45255" checksum="367448A7DE87D5FD" modified="2019-10-16" version="1">MQMVSKHLPKLVTATLVLVTLVVASILYSRYSTHPWTRDAQVRADLVKIAPRVQGYLVRVAVKDNQFVHKGDLLFQIDPTSFQLAVDQAKVELDQAREDVAALESAVVAAEAGIKQSNAAVSSAESKIKEAQASVAAAESTVKQAESGVTSAQADVKQNEAMLDEAQREATRARRLADQKAGSVEEAQAKEAAVAVHQAQLQSAEAKQRQAEAVLDQSRAGLGAAKAKLLTANNGLAEAQAAVATATAKAEQARANLGVPGEANVRIRSAKVHLDEAQLKLSWTNIYAPADGYITNMDLLESAFVFPGIPFALFVDAASFRVDAYFEETKVKYIHPGDHVTVTLMGHHDRQLEGEVDSIGYAINPPKLANTSGPANLVPTIEPTFEWIRLAQRVPVRIRFKSIPDDLQLISGTTASVAIKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZP5</accession>
    <name>A0A518IZP5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_45910</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="335" mass="37261" checksum="C2F55022569D4A7E" modified="2019-10-16" version="1">MDKSLDQKLARIAADPTCNDFILADAKDPDLAFGLMGPGPAAADQRHRYRTLDEFRDIIREIVDRKLVDIMLMSASTNEILTIDERIFDDSPVTPAARANDTTDIWFAPGSHYRHQPSLPFSSTTIDHIQSGKYECRDVERTQGANLGLYSITLNNDAQRDALTLNHYKQFRLEAEQKGFRHFLEVFAPNALVHPVEDVASYVNDCIVRLLGGVTRAGRPLFLKMPYFGPAAMEALVRYDSSLVVGILGGSAGTTMDAFRMLADAKKYGARVALFGRKINFAEDQIAFIGYLRQLADGTITAEEAVRAYHGDLQTLGKTPHRELADDLQITHCPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZS3</accession>
    <name>A0A518IZS3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_45580</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007801">
        <property type="entry name" value="UPF0276"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42194">
        <property type="entry name" value="PTHR42194"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05114">
        <property type="entry name" value="DUF692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="SSF51658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="330" mass="37309" checksum="E807E0883A433CC1" modified="2019-10-16" version="1">MTDSNQEPSPTVSGLGLGVGLRTAHFAHILEHQPAVDWFEIISENFMDCQGRPRYVLDQIAERYPIVMHGVSMSIGSSDPLNLEYLQKLKRLADETGARWVSDHVCWTGIAAKNTHDLLPIPYNEESLRHVCDRIRIVQEILERPLVLENPSTYVTFRDSTMSEWEFIRRMTIESGCQLLLDVNNVYVSSVNHDFSPTEYLDSIPADRVVQFHLAGHTDLGTHCIDTHDGRVVDRVWELFRYAYLRGIRASTLLEWDANIPEFDVLHAEVLKAKAYLRSAQAEPLEVGDVSPESASVRPTISVETSVDRASATRRNAIPQPALFSRAEVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZU6</accession>
    <name>A0A518IZU6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Endonuclease/Exonuclease/phosphatase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_46350</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="SSF56219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endo/exonuclease/phosphatase" evidence="1">
        <location>
            <begin position="39"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="289" mass="31544" checksum="07FC7D2535A73165" modified="2019-10-16" version="1">MNISRRHFSAAIAAAGLSTTTTTPGFADATKSAPLRVISYNVLVCRGWPKTRRLAKLAVKKGQMADRLALELALHEPDVVNFSESPSEAITQAVAEKLGMHHVRFPSGGNWPGTLLSRFPIAHSQNAPLGGPRPKDLYTRHWGRAELQMPSGDPLIVHSAHLFPGADPAVRLKEIRTMLKSMKSDFDAGRSMLLIGDLNHGPDTDEYKLWIDAGWIDTFAAVGKGEGLTFTADNPRYRIDYVMAAGPIAQRITESRPLLEGAFRVDSQDPESFALSDHIPQLAVFGGKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZV9</accession>
    <name>A0A518IZV9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_46550</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="134" mass="15746" checksum="8FF56EE7F6156D33" modified="2019-10-16" version="1">MERWGKRMNDLNPYASPPPIEESPGQLMHRDTRVARGLLHRTITFAEPFQAQLDYDGKYFRQRVYVGQICVWHRISWLRIHPRIDFVWPAEVAGTAKPGRIEMKFNHLLQIVRFTVYCDGVVIYDEQKGMLTTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J005</accession>
    <name>A0A518J005_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Arylsulfatase</fullName>
            <ecNumber evidence="7">3.1.6.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Mal33_47000</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="PTM">
        <text evidence="3">The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the sulfatase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.6.1" evidence="7"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004065">
        <property type="term" value="F:arylsulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032506">
        <property type="entry name" value="DUF4976"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024607">
        <property type="entry name" value="Sulfatase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16347">
        <property type="entry name" value="DUF4976"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00149">
        <property type="entry name" value="SULFATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022191883" evidence="4">
        <location>
            <begin position="25"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase" evidence="5">
        <location>
            <begin position="29"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4976" evidence="6">
        <location>
            <begin position="415"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="modified residue" description="3-oxoalanine (Cys)" evidence="3">
        <location>
            <position position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR600917-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF16347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV58676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="471" mass="52847" checksum="2B8335DCEFA78C15" modified="2019-10-16" version="1" precursor="true">MKQRIGFLALALVSAFSFSTVSVAAESRPNIILFVTDDLSPDMGCYGNDAIKTPNLDALASDGVRFTNAFCTTASCSASRSVILTGLHNHKNGHYGHEHAYHHFTSFAKTKSLPVRLNAAGYRTGRIGKYHVAPESVYHFDEVLTGNSRNAVQMADRVQSFVKQDDKPFFLYFCTSDPHRGGSRPDLPLTPNAFGNKPEGYAGVDEVLYSPDDVIVPPYLPDTPVCRAELAQYYQSVSRIDQGVGRLAEVLKQAGAWDNTIVIFTSDHGIAFPGGKTTQYEPGLAIPMLVRDPRMPERGTVNPAMVSLVDMTPTILDMAGVKAPKKEFHGRSFLPILGEQDPSGWDVVYGSHTFHEIQMYYPMRTVRQRQYKLIWNIAHPLPYPFASDLWAAPTWQAQYEQGMQAMYGKRTVGRYIQRPEFELFDLKADPHETTNLADDPKYADRLAKMQAELKQFQEKTGDPWIMKWDYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0A8</accession>
    <name>A0A518J0A8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Type II secretion system protein F</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">gspF_2</name>
        <name evidence="9" type="ORF">Mal33_47940</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GSP F family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.81.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003004">
        <property type="entry name" value="GspF/PilC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018076">
        <property type="entry name" value="T2SS_GspF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042094">
        <property type="entry name" value="T2SS_GspF_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30012">
        <property type="entry name" value="PTHR30012"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00482">
        <property type="entry name" value="T2SSF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00812">
        <property type="entry name" value="BCTERIALGSPF"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="167"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="220"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="258"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="376"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="domain" description="T2SSF" evidence="8">
        <location>
            <begin position="68"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="T2SSF" evidence="8">
        <location>
            <begin position="273"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV58769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="403" mass="43270" checksum="F1AB9D06DCFAA591" modified="2019-10-16" version="1">MAEFAYTARSMDGQRVTGTLTAASEREVSAQLAGKNLFPVDVKEVKEQSAMQLLGSSGRVNGQTMAIFYAQLGSLLRSGVPMIRSLTLLSEQASNNTLKEVLQDIKTRVEDGEPLGEALARYPRVFSSMGINMVRAGMEGGFLEDALDRVGEFTELQEDLKGRTASALAYPIFLSVVGTVVVTILLVFFVPKFGELFARLEAKGQLPLATTTLLAFSELLQSYGLFLLAGLIAGGFFLKMQLATEAGQMWADRVKIKLPIVGGILLSLAVARFCRVLGTLLTNGVPILRSLEISRAAAGNRVLGIAVADAAESVQSGETLSSPLASSGHFPATVTEMIRVAEESNTLDNVLIQIADGLEKRTFRRLDLFVRLLEPVMLLVLAGVVLFVVMALLLPVIKSSSAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0E1</accession>
    <name>A0A518J0E1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 11">ATP phosphoribosyltransferase</fullName>
            <shortName evidence="11">ATP-PRT</shortName>
            <shortName evidence="11">ATP-PRTase</shortName>
            <ecNumber evidence="4 11">2.4.2.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11 14" type="primary">hisG</name>
        <name evidence="14" type="ORF">Mal33_48360</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10 11">Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>1-(5-phospho-beta-D-ribosyl)-ATP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + ATP</text>
            <dbReference type="Rhea" id="RHEA:18473"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:73183"/>
            <dbReference type="EC" id="2.4.2.17"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="11">Feedback inhibited by histidine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 1/9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the ATP phosphoribosyltransferase family. Long subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.17" evidence="4 11"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00006"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003879">
        <property type="term" value="F:ATP phosphoribosyltransferase activity"/>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00079">
        <property type="entry name" value="HisG_Long"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013820">
        <property type="entry name" value="ATP_PRibTrfase_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018198">
        <property type="entry name" value="ATP_PRibTrfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001348">
        <property type="entry name" value="ATP_PRibTrfase_HisG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020621">
        <property type="entry name" value="ATP_PRibTrfase_HisG_long"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013115">
        <property type="entry name" value="HisG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011322">
        <property type="entry name" value="N-reg_PII-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015867">
        <property type="entry name" value="N-reg_PII/ATP_PRibTrfase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21403">
        <property type="entry name" value="PTHR21403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01634">
        <property type="entry name" value="HisG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08029">
        <property type="entry name" value="HisG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54913">
        <property type="entry name" value="SSF54913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00070">
        <property type="entry name" value="hisG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03455">
        <property type="entry name" value="HisG_C-term"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01316">
        <property type="entry name" value="ATP_P_PHORIBOSYLTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 11 14" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9 11" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11 14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HisG" evidence="12">
        <location>
            <begin position="54"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="HisG_C" evidence="13">
        <location>
            <begin position="211"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF08029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="QDV58811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="286" mass="30777" checksum="FE0AF3607E3A211A" modified="2019-10-16" version="1">MGTNNNLRIGLPSKGRLSDLAGDLLKQAGLRFRRQNRSLFARVSDLPVDLIFLRTDDIPTLCAEGAIDMGITGSDLVDEAGADVSVRMPLGVGRCRLAICVPEDSPAQSGKDLAGARIATSFPNISAKHLAQYGVTPHVVNLSGSVEVMISLGIADAIVDLVETGSTLAANKLRILEEIDTYETVLIQNGKCRDTVTAERIVRRLEGVVIARDFSLLEFNIPKSALAAAEKITPGFKSPTINSLEDQEWCAVRVMVKRSEVISAMEQLESVGASAIMETEITNCRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0E3</accession>
    <name>A0A518J0E3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_48270</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
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    <proteinExistence type="predicted"/>
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    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021998836" evidence="2">
        <location>
            <begin position="19"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
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            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="249"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="249"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="609" mass="63831" checksum="07A3C3424728EB2C" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J142</accession>
    <name>A0A518J142_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_50500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
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                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV59025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="170" mass="19432" checksum="CF069F64E284A116" modified="2019-10-16" version="1">MQCNRVALAAVLELLINRRDRLIAGVRRPKPIVHTPIVHAEITFLREHEGGRKFLPIMGIEAKYRPHLVIQDRTVRKSVIESDGLIRESYLGVQFNNEIKEFESVSGEWTRRYELSLMYHSRVDYSAVLPRATFTVREGGKIVGHGIVLKRFQPDTEKDGEPGDARESPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1F7</accession>
    <name>A0A518J1F7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_52080</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
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            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022068108" evidence="2">
        <location>
            <begin position="27"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV59180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="234" mass="25257" checksum="346589096148EBBC" modified="2019-10-16" version="1" precursor="true">MITVKSRQCNAALAIVVAAWASIASAGEDPDAGPNLSKWTLELRGALKREATTRETAAHSAAVIELCEMCAAMRSDDRYPTSEVLQGLATRARRRLLDVRYDIQVALKRDGIEKPAAFDQQLQKLERLLDKRAAAGKRLTPEELPSSAANSPGEGSADSQQTRLPGGGFAPGPDNGFLLIELITRTVSPDFWSAQGGPGAVHYYGMHRVMVVRATSRVHEDIQSLLHALGGFPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1Q6</accession>
    <name>A0A518J1Q6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Prephenate dehydratase</fullName>
            <ecNumber evidence="3">4.2.1.51</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">pheA</name>
        <name evidence="11" type="ORF">Mal33_52890</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H(+) + prephenate = 3-phenylpyruvate + CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:21648"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:18005"/>
            <dbReference type="ChEBI" id="CHEBI:29934"/>
            <dbReference type="EC" id="4.2.1.51"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-phenylalanine biosynthesis; phenylpyruvate from prephenate: step 1/1.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.51" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00121">
        <property type="reaction ID" value="UER00345"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004106">
        <property type="term" value="F:chorismate mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004664">
        <property type="term" value="F:prephenate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009094">
        <property type="term" value="P:L-phenylalanine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008242">
        <property type="entry name" value="Chor_mutase/pphenate_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001086">
        <property type="entry name" value="Preph_deHydtase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01842">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00800">
        <property type="entry name" value="PDT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001500">
        <property type="entry name" value="Chor_mut_pdt_Ppr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51171">
        <property type="entry name" value="PREPHENATE_DEHYDR_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-0584">Phenylalanine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Prephenate dehydratase" evidence="9">
        <location>
            <begin position="79"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="domain" description="ACT" evidence="10">
        <location>
            <begin position="265"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="site" description="Essential for prephenate dehydratase activity" evidence="8">
        <location>
            <position position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR001500-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QDV59261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="356" mass="38412" checksum="FAC3188A0D0FC125" modified="2019-10-16" version="1">MPRDPERLNAIDTSILDLVAQRIDILRQAGGAELPAEANARIQAAVDRTATDHQIDPERLRTLLRHVASLSAAELEPRRVAYLGPQHSYSHLAALKYFGDAATLTPESTIAAVFDAVVRGQAAMGIVPVENSTDGRVVDTLGMFVQNPVNICGEVLLPIHHYLLSSTPRDQIVEIYSKPQALSQCRGWLAQHMPDVHLKELSSTAAAAKLAAEQPGVAAIASEAAGREYGLNVIAASIEDNPNNVTRFAVLGGHEPSSSGDDKTALVLQIIHRPGALADVMNVFKTHNLNLTWIESYPMPAGPNEYLFFLELEGHKQDATVMAAIEDLKALTIRRDVLGSYPRGRETAESKSAAGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1S3</accession>
    <name>A0A518J1S3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_53060</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021823969" evidence="1">
        <location>
            <begin position="27"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="137" mass="14255" checksum="D4B52E466997C093" modified="2019-10-16" version="1" precursor="true">MYSSVRPILSSMLCCVIAFGHTPAWMHVATCDGDCKVVDAAIVQARSVCSHGCDHHVFANESTDNSANAPTSAPAQDHDSDTCVICQSLANCCGPVSLDLQLLAPEYACEPAYELATPLPIDASIAIAQPRGPPAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J2A1</accession>
    <name>A0A518J2A1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_54950</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="176" mass="20694" checksum="C4BF6350CD241025" modified="2019-10-16" version="1">MRQTVPNSQDPEPTQLYLYERKQRHTALVLLLNMGVLIAMYAAARKWIEPSEARDQLFYWINIAVPVVEVCLLLLAIYFWLKNGRFRMSVDTNRFTIDDPISKTYSFSVPVSEIEGIRQTYRNHTNYTTTVMYLKSGETIQLTPNYNYSRRALYDALKEANSTIQLPEHPYRFKQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ILW0</accession>
    <name>A0A518ILW0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_00080</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="139" mass="15233" checksum="ABC2BE6872D992ED" modified="2019-10-16" version="1">MMTEIDIMEEKSTASAVPLSRGVVFRVPAAGAGVMLLASLGFHTAPPPDLYDIDLPELRQAAASLDFFGYRGCDPNYHYFSLPNSQGLRLPQQQIDLQPLPIQLGLCLFVTFRNGRLTIPDPVAMASIEPPTCDWALGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ILW7</accession>
    <name>A0A518ILW7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_00330</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011453">
        <property type="entry name" value="DUF1559"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07596">
        <property type="entry name" value="SBP_bac_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="346" mass="36750" checksum="0877F53EE33B380C" modified="2019-10-16" version="1">MRKSKLSNPTGGFTLIELLVVIAIIGILVSLLLPAVQSAREAARRMSCGNNLKQLALATHNYESTYRVIPAMTGSSSYSVQARVLPFIEQGNLAELIDFESPLLVGPAWAAQFNPVLRGAIESVLPTFLCPSDAGDPQFATTFADGSAGYTAGLTYMFSYGSGTDTHYDDRYRTDGMVWTDSWAGFKDCLDGTSHTVLIAETVLGDQTSGETEPSPTGPQRRIANWGGTSSNPSGAGFMSGGALITNPDLQAVVPGSITSYQGNRGASWIRGVPYATVINGYMSPNSDLPDVGMHGRGFYSSRSYHPGVAGHAMLDGSVRFIGDSIDLPTYHAAYSRDGGEVVQLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ILX8</accession>
    <name>A0A518ILX8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">16S ribosomal RNA methyltransferase KsgA/Dim1 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Mal33_00470</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000179">
        <property type="term" value="F:rRNA (adenine-N6,N6-)-dimethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001737">
        <property type="entry name" value="KsgA/Erm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020598">
        <property type="entry name" value="rRNA_Ade_methylase_Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11727">
        <property type="entry name" value="PTHR11727"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00398">
        <property type="entry name" value="RrnaAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00650">
        <property type="entry name" value="rADc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="rADc" evidence="4">
        <location>
            <begin position="41"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV54106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="198" mass="21566" checksum="192E150D446A2DFB" modified="2019-10-16" version="1">MTTHAAPLRRRPYWTRAAAVLQEWIREPAQVASLVPSAPALTQRVAKQPGVSNATKIVDLGPGTGGTTEALLAAAAENCRVLAIEKAAGFIEPLNEIVDGRLTVEHADVVGLERILLIHQMTSPDVIVSGIPFSSLDRRVATDIIKSVHRTLPKGGTFIAYQLRSDVARYASPLFGTPQTEIVWMNVPPLRIFTWTKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IM42</accession>
    <name>A0A518IM42_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Mal33_00790</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0410 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007341">
        <property type="entry name" value="Transgly_assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33884">
        <property type="entry name" value="PTHR33884"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04226">
        <property type="entry name" value="Transgly_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="34"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="57"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV54133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="84" mass="8778" checksum="E14EDBF6603AFB3B" modified="2019-10-16" version="1">MFSIIGWIFFGLLVGLIARMLVPNTQAMGCMQTIMLGVAGSFVGGAIGYLLQGGSAVQSSGWIGSIVGAILLLVISVRRSKFID</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMJ2</accession>
    <name>A0A518IMJ2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_02600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011453">
        <property type="entry name" value="DUF1559"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07596">
        <property type="entry name" value="SBP_bac_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="345" mass="36654" checksum="2140AF508F36D77E" modified="2019-10-16" version="1">MKRSRSAFTLVELLVVIAIIGILVGLLLPAVQAAREAARRMQCSNNMKQLGLALHNYHDTHGSFVPRATGTTSGTFQNNGRLNGLIPLMPFYEQGPMFDKIAAGDGTRPPFGGNTWDSWAPWNVAPDMLHCPSDNFSGSQTNHFNYRFSLGDQMGSTRDKTTLRGVFAKRDGTRFRDILDGTSNTIAMSERKVNSYSQGTRTGTIRVAEGVTTGVTDIQLSPLNCLAETDGTFYLDASVVKGRGGWWLADGQAERAGFNTVLPPNSASCADGTSSSGDSVTSVIAPTSNHPGGVMTVRADGSTHFVAETIDTGDLSQPERTNGLSPYGIWGAMGSKAGGEPAAGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMM6</accession>
    <name>A0A518IMM6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_02900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041916">
        <property type="entry name" value="Anti_sigma_zinc_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="131"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="180"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="430" mass="45690" checksum="5E38448E5BE5A694" modified="2019-10-16" version="1">MNNEAREELLSAYLDNGLSADEQAHVEQLLQHDASVRQQLEALRKLQADVRASMPSDARLGTDFSDRVWTAVLAQADAEGLPDTHPIRLAQAREGRGNFKRHQRAWLGGLAALAASLTLIVAWNSSNPDIQPGSPQAAGGLAAVATPGTPDSSDPVEPSPIETTAPTAQPAVEAIASNDAATTPAAPAPAVTPPEAAETTAQPDKTTAPEERIAMAPAATVQPAAAPGELVSPSAQPTNKLEFAVLLEVELTQRGRDLNELEYALETAGISNVQPQPMSRDHVGQLVQGKMIGTVNLDAPQAVEGDTQLLLLQGSAKRLDRFMLSLFNHQSVIKSVGFQMVMEPNLLTTISELSSVAPSAIRHADDKALAHHLTFGSAGGQAQMFPRAAQSSFFALTEESAKQMKWTPETPSDEGPDFQTQMLVLVRCPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMZ6</accession>
    <name>A0A518IMZ6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Planctomycete cytochrome C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Mal33_04210</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011429">
        <property type="entry name" value="Cyt_c_Planctomycete-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011444">
        <property type="entry name" value="DUF1549"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022655">
        <property type="entry name" value="DUF1553"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07635">
        <property type="entry name" value="PSCyt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07583">
        <property type="entry name" value="PSCyt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07587">
        <property type="entry name" value="PSD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="2 3" id="KW-0408">Iron</keyword>
    <keyword evidence="1 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome c" evidence="5">
        <location>
            <begin position="52"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="419"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV54467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1157" mass="128715" checksum="FC4ADB8DF6E766AF" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IN13</accession>
    <name>A0A518IN13_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ribosome-binding factor A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1 3" type="primary">rbfA</name>
        <name evidence="3" type="ORF">Mal33_04350</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RbfA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030490">
        <property type="term" value="P:maturation of SSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00003">
        <property type="entry name" value="RbfA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000238">
        <property type="entry name" value="RbfA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023799">
        <property type="entry name" value="RbfA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33515">
        <property type="entry name" value="PTHR33515"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02033">
        <property type="entry name" value="RBFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89919">
        <property type="entry name" value="SSF89919"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00082">
        <property type="entry name" value="rbfA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="135"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="156" mass="17106" checksum="0DD8B37DA53AAB68" modified="2019-10-16" version="1">MIAGAVLGGSLFLLTHLFLNFGNPIVTSRRQLKAAEAIREVVATSILTELRDPRVKDVTVIGVEIDPDMRNAKVRVSVMGDEKQQTLTLRGLQNSAGYLQSKIAARIDTRYTPRLTFKIDKGLNNALEVSRILEELRKETPPASDDSATDGSEDPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IN71</accession>
    <name>A0A518IN71_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative periplasmic serine endoprotease DegP-like</fullName>
            <ecNumber evidence="3">3.4.21.107</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">degP1</name>
        <name evidence="3" type="ORF">Mal33_04900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.4.21.107" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
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        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001940">
        <property type="entry name" value="Peptidase_S1C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13180">
        <property type="entry name" value="PDZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PROTEASES2C"/>
    </dbReference>
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        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDZ" evidence="2">
        <location>
            <begin position="320"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="420" mass="45251" checksum="1DDBAE8E0FCD298E" modified="2019-10-16" version="1">MNHLDFDVEPAEYSRPADAWPQSTPSPKPPKEIPPLRNQSSSPGAAQALVSLVMLGVLLLATRFLVPTLVEEIRYAWHRGELRAEYESSGEGLRNVSMNSLAQAYQMVTQRVGPSVVHIDVERDLTEQERELAVAIRRGSGMELPGDQGSGVIVDDQGFVLTNYHVIEGGSDIHVGLSDGRRVSAEVVGMDALTDIAILKIEANGLLPVRWGDSDKSEVGTPVWAVGSPFGLDRTVTFGILSGKHRATKAGTRYQDFMQSDVAVNPGNSGGPLINSAGELIGINTAIVGETYRGVSFSIPSNVAKQVYERLRSSGYVNRGWLGVALDEVPESRRHGDDPLIRGALVRGLANGSSPARNAGILPDDIIIAFNSQPVRDMGALMRMVGDTTGGSTVSMEIYRGDSTRLVDVEIGMRPDDLKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INA4</accession>
    <name>A0A518INA4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_05330</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0301 (AlgH) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003774">
        <property type="entry name" value="UPF0301"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30327">
        <property type="entry name" value="PTHR30327"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02622">
        <property type="entry name" value="DUF179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="182" mass="19608" checksum="A174430377D33B6A" modified="2019-10-16" version="1">MEQSIVGNLLVAAPALDGTLFQRSVCLLLHHDQENVIGVVLNRPLFGGVSLPQGNSPALLVKQSLHLGGPNAGPVFALHNCADLAELETGTGLYMASSRQHMQRLLADASLPCRLIVGHVQWSIKDLQSQLSSDLWRVLPATPEAVFEPDDLMWSDLARKSAALHFAHLVGAKHIPSHPALN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INC0</accession>
    <name>A0A518INC0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Quinoprotein glucose dehydrogenase B</fullName>
            <ecNumber evidence="10">1.1.5.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">gdhB_1</name>
        <name evidence="10" type="ORF">Mal33_05360</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.5.2" evidence="10"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008876">
        <property type="term" value="F:quinoprotein glucose dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006584">
        <property type="entry name" value="Cellulose-bd_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005084">
        <property type="entry name" value="CMB_fam6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002324">
        <property type="entry name" value="Cyt_c_ID"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012938">
        <property type="entry name" value="Glc/Sorbosone_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022409">
        <property type="entry name" value="PKD/Chitinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000601">
        <property type="entry name" value="PKD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035986">
        <property type="entry name" value="PKD_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011041">
        <property type="entry name" value="Quinoprot_gluc/sorb_DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03422">
        <property type="entry name" value="CBM_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07995">
        <property type="entry name" value="GSDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00606">
        <property type="entry name" value="CYTCHROMECID"/>
    </dbReference>
    <dbReference type="SMART" id="SM00606">
        <property type="entry name" value="CBD_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00089">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49299">
        <property type="entry name" value="SSF49299"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50952">
        <property type="entry name" value="SSF50952"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51175">
        <property type="entry name" value="CBM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50093">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="1 5" id="KW-0349">Heme</keyword>
    <keyword evidence="3 5" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022241641" evidence="6">
        <location>
            <begin position="30"/>
            <end position="893"/>
        </location>
    </feature>
    <feature type="domain" description="PKD" evidence="7">
        <location>
            <begin position="497"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="8">
        <location>
            <begin position="630"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="domain" description="CBM6" evidence="9">
        <location>
            <begin position="767"/>
            <end position="893"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV54581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="893" mass="97713" checksum="9C96838A22ABB0CF" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INC1</accession>
    <name>A0A518INC1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Sensor protein ZraS</fullName>
            <ecNumber evidence="4">2.7.13.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">zraS_1</name>
        <name evidence="4" type="ORF">Mal33_05170</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.13.3" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PAS" evidence="3">
        <location>
            <begin position="112"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="2">
        <location>
            <begin position="241"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV54562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="453" mass="49681" checksum="58C1D49E382A1071" modified="2019-10-16" version="1">MFEIQDGPIGRGIRRIAAGLAVLSLTSLLLTGKILLDVHHEHEIMARLVLHLPPSDAAAAEGLLGELRLDRMLTILLVVNLSGTTIALALVVRGYLSSERSLRAVKVLATDILASMDAGVITTDRNGRISSTNPRAQTLLGSPDNEGVGQYLSDLGDEHALLDSICSEVRTYHDAIRDRDYCVTSNGHRQTLRAGCTLLSNQQGEDIGTVLHVRDVTEKALIEERLRRMERYMGLGSLAAGLQHEIKNPLSAVSIHIQLLCEHLASEPYDPEVAELLDVLQTEVQRINNVLDGFRNYASMSEIGRSAVDVTLLIDKLVRLLRPQADQQQVKIKIESPPEMLGLIQADSVRLEQVFLNLALNAMAAMPDGGLLRFRVGQLNDQIRIDIADTGNGILPEIQSQIFDPYFTTRSEGTGMGLALCDKIIRQHDGSIDFRTSPDGTEFTVLLPRGTQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INE3</accession>
    <name>A0A518INE3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_05370</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011453">
        <property type="entry name" value="DUF1559"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07596">
        <property type="entry name" value="SBP_bac_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="331" mass="35526" checksum="8A9D7AB90B74641C" modified="2019-10-16" version="1">MIQRNHRSSRGGFTLVELLVVIAIIGILVGLLLPAVQAAREAARRMQCGNNLKQIGLAMHNYHDTFQVFPSGCYDSNPATNSPGDAANNNNGLGWATSLLPYIEQSALYDLIGTETGGFARSWQDKNGDGSANDPIDSASVVIDAYVCPSDPMSGINSDKSNLGKSNYLAIAGRSAIQTNSSGNPLGTKNGMFFENSNRRFRDVTDGTSNTMFVSERTTQDDRIGSLQCGGTDCNWAGGIWIGPRIISATETWHTGLRMLDVTNVGGESLTYGLGRTTASWADDWSAKGCHPGGMQVTLGDGSVRFMTETIDLITYRDLHTPQDGNVIAPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INE6</accession>
    <name>A0A518INE6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_05690</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="72" mass="7759" checksum="54B44345ADAF04C4" modified="2019-10-16" version="1">MTDLLEKAFEHASKLPPQQQDALAKWLLNEIAADNAWDATFAKSPALLASLASEALQEKDGGDAQPLVPDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INL1</accession>
    <name>A0A518INL1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Anaerobic glycerol-3-phosphate dehydrogenase subunit C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">glpC_1</name>
        <name evidence="6" type="ORF">Mal33_06390</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.45.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004017">
        <property type="entry name" value="Cys_rich_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016164">
        <property type="entry name" value="FAD-linked_Oxase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004113">
        <property type="entry name" value="FAD-linked_oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016171">
        <property type="entry name" value="Vanillyl_alc_oxidase_C-sub2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02754">
        <property type="entry name" value="CCG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02913">
        <property type="entry name" value="FAD-oxidase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55103">
        <property type="entry name" value="SSF55103"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
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    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="37"/>
            <end position="256"/>
        </location>
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            <end position="649"/>
        </location>
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        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="QDV54683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="980" mass="108643" checksum="C41B9B733A2048F3" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INN8</accession>
    <name>A0A518INN8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Metallo-hydrolase YycJ</fullName>
            <ecNumber evidence="3">3.-.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">yycJ</name>
        <name evidence="3" type="ORF">Mal33_06660</name>
    </gene>
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        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
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    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="2">
        <location>
            <begin position="11"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="273"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="278"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="318" mass="34713" checksum="CDC2FCA4B53A6F59" modified="2019-10-16" version="1">MEVITLQSGSSGNCVYVETDGVRLLFDAGISGRQAQERLAQHGKDIHDVDALIISHDHSDHTSCMGVYHRKFGLPIYCTPATHTIVDRRKRLGRVSDVRHFDAGETLWFGQVAVETLSTPHDGADGVVFIIDNSRRRFGILTDLGHVFDGLEAAVASLDAVLIESNYDPVMLAEGPYPPALQERISGPGGHISNLEAARLLQRTDSSRLQWACLAHLSDENNAPDVALQTHRQLLGSEFPVSCADRFLATDPLKVEDPCEGIVAVCDADDETSSTDRCTDADSQQSAPENAQSSKRRSSRKRIAAGFSQLTFFDDACH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INS9</accession>
    <name>A0A518INS9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="21">30S ribosomal protein S13</fullName>
            <ecNumber evidence="6">3.2.2.23</ecNumber>
            <ecNumber evidence="7">4.2.99.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="25" type="primary">mutM</name>
        <name evidence="25" type="ORF">Mal33_06980</name>
    </gene>
    <organism evidence="25 26">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="25 26" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="25 26">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-monophospho-2'-deoxyribonucleoside-DNA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66592"/>
            <dbReference type="Rhea" id="RHEA-COMP:13180"/>
            <dbReference type="Rhea" id="RHEA-COMP:16897"/>
            <dbReference type="Rhea" id="RHEA-COMP:17067"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:136412"/>
            <dbReference type="ChEBI" id="CHEBI:157695"/>
            <dbReference type="ChEBI" id="CHEBI:167181"/>
            <dbReference type="EC" id="4.2.99.18"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of DNA containing ring-opened 7-methylguanine residues, releasing 2,6-diamino-4-hydroxy-5-(N-methyl)formamidopyrimidine.</text>
            <dbReference type="EC" id="3.2.2.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the FPG family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the universal ribosomal protein uS13 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.23" evidence="6"/>
    <dbReference type="EC" id="4.2.99.18" evidence="7"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140078">
        <property type="term" value="F:class I DNA-(apurinic or apyrimidinic site) endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008534">
        <property type="term" value="F:oxidized purine nucleobase lesion DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015886">
        <property type="entry name" value="DNA_glyclase/AP_lyase_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020629">
        <property type="entry name" value="Formamido-pyr_DNA_Glyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012319">
        <property type="entry name" value="FPG_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035937">
        <property type="entry name" value="MutM-like_N-ter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001892">
        <property type="entry name" value="Ribosomal_S13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010979">
        <property type="entry name" value="Ribosomal_S13-like_H2TH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000214">
        <property type="entry name" value="Znf_DNA_glyclase/AP_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010663">
        <property type="entry name" value="Znf_FPG/IleRS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01149">
        <property type="entry name" value="Fapy_DNA_glyco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06831">
        <property type="entry name" value="H2TH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06827">
        <property type="entry name" value="zf-FPG_IleRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00898">
        <property type="entry name" value="Fapy_DNA_glyco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01232">
        <property type="entry name" value="H2TH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46946">
        <property type="entry name" value="SSF46946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81624">
        <property type="entry name" value="SSF81624"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00577">
        <property type="entry name" value="fpg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51068">
        <property type="entry name" value="FPG_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50159">
        <property type="entry name" value="RIBOSOMAL_S13_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51066">
        <property type="entry name" value="ZF_FPG_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0227">DNA damage</keyword>
    <keyword evidence="15" id="KW-0234">DNA repair</keyword>
    <keyword evidence="14" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="19 25" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="11 25" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="16" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="26" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="18" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="13" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="12" id="KW-0862">Zinc</keyword>
    <keyword evidence="10 22" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="FPG_CAT" evidence="24">
        <location>
            <begin position="2"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="FPG-type" evidence="23">
        <location>
            <begin position="241"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00012720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00024490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00029533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="PROSITE" id="PS51066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="PROSITE" id="PS51068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="EMBL" id="QDV54738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="289" mass="32389" checksum="28F24280D12DA7FE" modified="2019-10-16" version="1">MPELPEVETMRRGILPIVGATIASVQRPPCHCRPISIKPRIDHLDRRASGRTIADIDRLGKRVVIHLDDGQAIVIEPRMSGLVLLADPPGIEHLRLRIELNGVTHRELLFWDRRGLGTVRLLSAEELKTLVTERLGPDALQISTDQLRGALRASRRAIKVALLDQSVVAGIGNLYAAEILHLAGVDPRTRCDQLSRPQWQRIQAAIGQILETAIRHEGSTLSDGTYRNALNDPGNYQSQHQVYDRADQTCYRCDRGPITRIVQAQRSTFYCPTCQQKRGLHESLADYRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INT7</accession>
    <name>A0A518INT7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Sec-independent protein translocase protein TatAd</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">tatAd</name>
        <name evidence="9" type="ORF">Mal33_07160</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043953">
        <property type="term" value="P:protein transport by the Tat complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003369">
        <property type="entry name" value="TatA/B/E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006312">
        <property type="entry name" value="TatA/E"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02416">
        <property type="entry name" value="TatA_B_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01411">
        <property type="entry name" value="tatAE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0811">Translocation</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="49"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV54756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="64" mass="6934" checksum="96CA9BA717015313" modified="2019-10-16" version="1">MTQLLGIGMPGLPEMMIILVILLVLFGGAKLPTLMRNLGRSANEFKHGLNDPVSEDSDKDKPAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP05</accession>
    <name>A0A518IP05_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">N-carbamoyl-D-amino acid hydrolase</fullName>
            <ecNumber evidence="2">3.5.1.77</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_07860</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.5.1.77" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047417">
        <property type="term" value="F:N-carbamoyl-D-amino acid hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="SSF56317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CN hydrolase" evidence="1">
        <location>
            <begin position="6"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="279" mass="30449" checksum="2B0E470108D56E33" modified="2019-10-16" version="1">MSQQTKRVAAVQMDVAFADIDHNVQQILAKIATVKADGVDLAVFPECALTGYCFESREEALPLGLSIDDPLFDSFAAACGDSDLHVIIGFLEIEGDKLFNSQAMINRSGVVGSYRKIHLPGVGVDRFLDPGDREFSIQAAGEIRVGMAICYDSSFPETSRVLGLHGADVIALSTNWPVAARRTAEIVPPARSMENHLYFIAANRVGTERTFEFCGMSSIAGPDGVMIAETDSDQELILTADIDLSIARNKQIVRTPGKHVIDRFADRQPERYTIIGEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP66</accession>
    <name>A0A518IP66_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cobalt-zinc-cadmium resistance protein CzcA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">czcA_1</name>
        <name evidence="4" type="ORF">Mal33_08580</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2090.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004763">
        <property type="entry name" value="CzcA/CusA/SilA/NccA/HelA/CnrA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82714">
        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00914">
        <property type="entry name" value="2A0601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="344"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="379"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="439"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="468"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="525"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="861"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="886"/>
            <end position="906"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="913"/>
            <end position="936"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="956"/>
            <end position="978"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="990"/>
            <end position="1016"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV54893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1036" mass="113029" checksum="18B5173657B051CA" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP88</accession>
    <name>A0A518IP88_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_08470</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="122"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="172"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="232"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="286"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="367"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="529" mass="59857" checksum="332692671214CF89" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP91</accession>
    <name>A0A518IP91_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_08630</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="326" mass="37506" checksum="5AEF099561270637" modified="2019-10-16" version="1">MFGVQRILCWLVLPATIGWGQADLQQIADARSYIESINDRAEAITRYDAAARRETMMLFPDGRLLEERSVERVMFDAQANRYLWIARKSQNLKRAYEAKEPAADVPLTTRYLAILYLDGQRYELDGGKVSKRMRESDKSSSFPGEGNVDFRKLGIGGSVSENEILLKLLASANSGDVITKGDRVEVQLATPEVTPYSDKPFTELQWRFDAKTTTVRLFQRIYHAFWRDKLYPSIQARARFQWQRIDEHDVPRTVLVENRFYLTHGPENLTGEVEPSYAPTTIDCHWFSLNQPLPDQPFSVDFLSDEKNLKSFVDPELNGAIRLMDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPD2</accession>
    <name>A0A518IPD2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PAP2 superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_09220</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002105">
        <property type="entry name" value="Dockerin_1_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="P_Acid_Pase_2/haloperoxi_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000326">
        <property type="entry name" value="P_Acid_Pase_2/haloperoxidase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00404">
        <property type="entry name" value="Dockerin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01569">
        <property type="entry name" value="PAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="SSF48317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="acidPPc" evidence="1">
        <location>
            <begin position="431"/>
            <end position="576"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="588" mass="62544" checksum="063C50BC4DBF80C3" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPL4</accession>
    <name>A0A518IPL4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Arylsulfatase</fullName>
            <ecNumber evidence="10">3.1.6.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Mal33_09960</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="PTM">
        <text evidence="7">The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sulfatase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.6.1" evidence="10"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004065">
        <property type="term" value="F:arylsulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004423">
        <property type="term" value="F:iduronate-2-sulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16030">
        <property type="entry name" value="iduronate-2-sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035874">
        <property type="entry name" value="IDS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0106">Calcium</keyword>
    <keyword evidence="5 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021943773" evidence="8">
        <location>
            <begin position="22"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase" evidence="9">
        <location>
            <begin position="25"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="modified residue" description="3-oxoalanine (Cys)" evidence="7">
        <location>
            <position position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR600917-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV55028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="471" mass="52210" checksum="43E940355047C6CC" modified="2019-10-16" version="1" precursor="true">MRLPILFAVAWLSCATLAASAAERPNVLLICVDDLRPELNCFGKSYIRSPNIDALAARGRIFERHYVQAPTCGASRFAMLTGRYGPSDNGALFKRAAQIAKNADSVSASMPAWFRQNGYTTVSVGKVSHHPGGRGGPDWDREDQLEMPHSWDRHLLPAGPWQHPRGAMHGLAHGEIRHDPSKMDLFQSSEGDDSIYPDGLITDEALRQLDRLSGDDGEQPFFLAVGIIRPHLPFGAPAKYMQPYRDLTLPPIPHPQKPSGKTTWHRSGEFMRYNRWGKDPNHDAEFATAVRKHYAACVSYADAQVGKLVQRLNQLGQQDNTIIVLWGDHGWHLGEHGIWGKHALFEESLRSPLVICHPGLPNPGVATRSIVESVDIFPTLCSLSGLPQPDFVDGVSLTPILQSADAAGHPAVSYAKAQTLRTDTHRLIVHRDGYVELYDHRGEDGETTNIAEKHPELVEAMLQQLRQRMEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPN5</accession>
    <name>A0A518IPN5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Adenylate cyclase 1</fullName>
            <ecNumber evidence="2">4.6.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">cyaA_1</name>
        <name evidence="2" type="ORF">Mal33_10220</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="4.6.1.1" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009190">
        <property type="term" value="P:cyclic nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00044">
        <property type="entry name" value="CYCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SSF49879"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Guanylate cyclase" evidence="1">
        <location>
            <begin position="336"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="592" mass="64621" checksum="B1F08FCAEF5903DA" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPY2</accession>
    <name>A0A518IPY2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aldehyde dehydrogenase AldA</fullName>
            <ecNumber evidence="3">1.2.1.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">aldA</name>
        <name evidence="3" type="ORF">Mal33_11250</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.2.1.3" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004029">
        <property type="term" value="F:aldehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043878">
        <property type="term" value="F:glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="2">
        <location>
            <begin position="37"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="496" mass="52551" checksum="A107A1647E0BFDA3" modified="2019-10-16" version="1">MSVMTKFELLPAVETFLKQSPFASFVGGQDFPAASGNLIPTIDPGSGDTIAEIHDLSPSEIDRAVEIADEAFPAWAGLSQQERSSILLRLADAVEADKAIIAQIEALDAGKIQAQAAGDVQNFVDTLRYFVGLADKVELRNKLDVPGHDAWTFKQPWGACAFIFPWNFPFLLIGWGISPALAAGNTVVIKPAEDTSLSALYLAQLAKKVGVPDGVINVVTGRGATAGAALSNNTKIKRMSFTGSPEVGQMVGESCGRNLVPVKLELGGKGAAVVFDDVDVKATAEALVGAITFHSGQVCCDATRWLIHENVYDEFVKHCVDRLKEVKIGHPLDPNAQMGPVVNPKQCQRVLGYQDKGKAGGAECLYGGGAATVEGYEGNYVKPALLAGSLDNVAAQEEIFGPVAYLAKFGSEQEAIAMANDTQYGLANSVWTKDDDRAARVAESMTAGNSWINAHNVFAHGVPYGGVNKSGMGGGVLSIETLMDYYRSTSVVRPLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQ09</accession>
    <name>A0A518IQ09_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Probable membrane transporter protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Mal33_11560</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002781">
        <property type="entry name" value="TM_pro_TauE-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01925">
        <property type="entry name" value="TauE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="77"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="105"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="136"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="174"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="207"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="235"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV55186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="270" mass="29757" checksum="A2D070A29DE75F80" modified="2019-10-16" version="1">MMEMLPLEELAAFAAVVCLGIFVQSATGFAGGLVIMPLMLWAGQGIPETQAALLVATTPQNAWGLWQYRQTVQLKEFAFPATLRMASLPVGIAVLSLIDGFPVQFMRQLIGAVVILCVMMLLIFRPTPREHLHVGWTWLAFLSSGFFQGCTGTGGPMMVLWVQAHDWSTKRTRAFLFTMYLVSMLPAWGLLYYWFGQRIINPSLTAMAIIPLLLVATWMGLHVGTWLGRHRLRRVTMCVLLVVGLVGLLSPLFSPARSAETSATTNANAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQ20</accession>
    <name>A0A518IQ20_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">RNA polymerase sigma factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_11400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011517">
        <property type="entry name" value="RNA_pol_sigma70_ECF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07638">
        <property type="entry name" value="Sigma70_ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="224" mass="25208" checksum="B83A8AAE404BDCE1" modified="2019-10-16" version="1">MILTRNYESLLSDKFNQVENTMNDDSDRSSQELDELIEGVRRGENFALEQVFNQYFPYLVAFARSRMRSRQLGGDVEGVAASAMRSFVSGAGAGRFGELKTQQDLFRLLSVIVLRKSIKYTKRDGRYIHISEAGDDSSSNGFFSIRSVPTGPVAEQALIVQETLDQLLQALGKNILQSIVLMQLEGHANPIIADTLRISIRSVQRHIRLIRQTLKKIELADNDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQ28</accession>
    <name>A0A518IQ28_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Oxygen-independent coproporphyrinogen-III oxidase 1</fullName>
            <ecNumber evidence="2">1.3.98.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">hemN_1</name>
        <name evidence="2" type="ORF">Mal33_11680</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.3.98.3" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051989">
        <property type="term" value="F:coproporphyrinogen dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034505">
        <property type="entry name" value="Coproporphyrinogen-III_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023404">
        <property type="entry name" value="rSAM_horseshoe"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13932">
        <property type="entry name" value="PTHR13932"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Radical SAM core" evidence="1">
        <location>
            <begin position="40"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="436" mass="49648" checksum="204B72E6577C1E5A" modified="2019-10-16" version="1">MSTTDSKTEVGSYFISNYPPYSQWTVDALPTVEQTLGSAPKPDTPLGLYLHIPFCRKRCKFCYFKVFTDVKAPEVQRYVDALCSEIEMVSQLPVMGDRPFRFVYFGGGTPSFLSPKQLTALSERLHRHITWDGAEEVTFECEPGTLSETKVKTLRETLGVTRLSLGVENFTDSVLEENGRAHLSKQVYTAWEWIEAANFNNVNIDLISGMVGETWDNWKYNIEKVIELSPESVTIYQMELPFNTVYSKDILGNKIETPVADWPTKRAWVAYAYEELKKVGYSVSSAYTMIKDPNKISFSYRDNLWRGSDLLATGIASFGHAQGVHYQNLPGMEQYLGAIEEGRLPLGRGFQPTEHQMLIREMVLLLKKGVLDVGYFRQKFGVDVIDRWRDVWQGYADEGLLSFSDDQVELTMDGLLRADSLLPAFFEPEHQGVRYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQ43</accession>
    <name>A0A518IQ43_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycine cleavage system H protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">gcvH_2</name>
        <name evidence="2" type="ORF">Mal33_11670</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005960">
        <property type="term" value="C:glycine cleavage complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019464">
        <property type="term" value="P:glycine decarboxylation via glycine cleavage system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06848">
        <property type="entry name" value="GCS_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002930">
        <property type="entry name" value="GCV_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033753">
        <property type="entry name" value="GCV_H/Fam206"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11715">
        <property type="entry name" value="PTHR11715"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01597">
        <property type="entry name" value="GCV_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="1">
        <location>
            <begin position="42"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="159" mass="17494" checksum="7A6601366A1CBDE2" modified="2019-10-16" version="1">MSESAESNDSLVFSMGEFQASFPQDRLYAKNHMWAMPTDAGRFRFGLSAYAVRLLQDVYFLDWIVDAGATIAASENIGSIESKKAESDLYSPLAGRLTAINPEALDDPSAINAEPYGAGWLIEIESDDASRLLDPEAYLKHLDSAWEVAQRTIKGQANQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQG6</accession>
    <name>A0A518IQG6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Flagellar P-ring protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">flgI</name>
        <name evidence="5" type="ORF">Mal33_12950</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Bacterial flagellum basal body</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009428">
        <property type="term" value="C:bacterial-type flagellum basal body, distal rod, P ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030288">
        <property type="term" value="C:outer membrane-bounded periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001782">
        <property type="entry name" value="Flag_FlgI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30381">
        <property type="entry name" value="PTHR30381"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02119">
        <property type="entry name" value="FlgI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01010">
        <property type="entry name" value="FLGPRINGFLGI"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="5" id="KW-0966">Cell projection</keyword>
    <keyword evidence="5" id="KW-0969">Cilium</keyword>
    <keyword evidence="5" id="KW-0282">Flagellum</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022148469" evidence="4">
        <location>
            <begin position="19"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV55324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="364" mass="38849" checksum="EFC7676C320C9A52" modified="2019-10-16" version="1" precursor="true">MNLLLRSILLCLVPSMLAASVSAEELKLRDICRIKGQEITTVQGLGLVVGLKGTGDPDAKPTAKALARMIQLMGGQISTDPRGQLMLDDVEQAGNVALVFVTARVPEVGAQQGDRLDCTVNAIGAKSLAGGTLMLSPLLGPRADQPTVYAMAEGPLRISNPDSPTSAMVHQGAKMERSLLAPFHENGKLTLILDRDFADFDTVQWIEDAINSQGEQPLTGESAGIDPSARVPVARAIDQLHIEVDIPPVYRNNPISFISLLLGLRVALPNNDTRVVINEREGVVVIGEEVRIAPVLITHRNLRIEAGARPGFVPVDAAAPKAENAKLKNLADALNALEVPTDDLIAIIKALKTKGDLYGDVIFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQN1</accession>
    <name>A0A518IQN1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cation efflux system protein CusA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">cusA_2</name>
        <name evidence="2" type="ORF">Mal33_13670</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
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        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82714">
        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="2"/>
    </dbReference>
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    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="345"/>
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    </feature>
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    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
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    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
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    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
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    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1037"/>
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    <feature type="transmembrane region" description="Helical" evidence="1">
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    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1117"/>
            <end position="1139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1171" mass="127937" checksum="FA13B6ED3B5C9D35" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQN8</accession>
    <name>A0A518IQN8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ribosomal-protein-alanine N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_13700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55399.1"/>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="60"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="223" mass="24820" checksum="AF493C9703AD2CCB" modified="2019-10-16" version="1">MKTQSTRSTRWLAYRVVRRFAIANVCHFYQSPIDKMPRTPTPSEYDICSCSSKRLREHASELDYAIPERDLEMLDAGAAKCFAAFQADSLAGFAWVAFGNITGEMNHDGKPETGLPIQLVDEAAFVFQVLVLPAYRGRRLYAAILSQMADQLQDNGMHTLVLTTEGSNQNALKAVQRMQFRKVGQASFFRIGPLSRATYPTLPNDIGFTIGRYVGDDTAAHSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQZ8</accession>
    <name>A0A518IQZ8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Carbamoyl-phosphate synthase small chain</fullName>
            <ecNumber evidence="2">6.3.5.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Carbamoyl-phosphate synthetase glutamine chain</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2 4" type="primary">carA</name>
        <name evidence="4" type="ORF">Mal33_14890</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>2 ATP + H2O + hydrogencarbonate + L-glutamine = 2 ADP + carbamoyl phosphate + 2 H(+) + L-glutamate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:18633"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.5"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-arginine biosynthesis; carbamoyl phosphate from bicarbonate: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 1/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the CarA family.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.5" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00171"/>
    </dbReference>
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        <property type="reaction ID" value="UER00115"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004088">
        <property type="term" value="F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01744">
        <property type="entry name" value="GATase1_CPSase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01209">
        <property type="entry name" value="CPSase_S_chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006274">
        <property type="entry name" value="CarbamoylP_synth_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002474">
        <property type="entry name" value="CarbamoylP_synth_ssu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036480">
        <property type="entry name" value="CarbP_synth_ssu_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035686">
        <property type="entry name" value="CPSase_GATase1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00988">
        <property type="entry name" value="CPSase_sm_chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01097">
        <property type="entry name" value="CPSase_sm_chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52021">
        <property type="entry name" value="SSF52021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01368">
        <property type="entry name" value="CPSaseIIsmall"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="2 4" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CPSase_sm_chain" evidence="3">
        <location>
            <begin position="19"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="CPSase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="278"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="362"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV55512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="390" mass="42741" checksum="2C960FD960BDD4A4" modified="2019-10-16" version="1">MRTQPHQPHPNTSFMNTRAPAKLALEDGTVYTGISVGADGEVDGEVVFNTAMTGYQEILTDPSYRGQIVTMTSPEIGNYGINDDDREHLVPRLSGFVIRESSRVYSNYRAQGGLTEYLRKHGVVAIAEIDTRALVRRIRDLGAMKGILSTTDLNDESLIAKAKASPGLVGRDLTCEVMPKSVETWDVRLDQWTDSQTPDSGAHIVCLDFGMKWNIPRHLHSRGNRVTIVPGSTSADEILALEPDGIFLSNGPGDPEPLQQAQETIRQLIGKKPIFGICLGHQLLSLACGAKAFKLKFGHRGVNQPVLDLTTGKIEITTQNHGFAIEQSSLPDCLEVTHMNLNDDTVAGVRHRQHNAFSVQYHPEASSGPHDSHYLFDRFQEAISAQPAGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IR28</accession>
    <name>A0A518IR28_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ribonuclease E</fullName>
            <ecNumber evidence="7">3.1.26.12</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rne</name>
        <name evidence="7" type="ORF">Mal33_15160</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="3.1.26.12" evidence="7"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004540">
        <property type="term" value="F:ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019307">
        <property type="entry name" value="RNA-bd_AU-1/RNase_E/G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004659">
        <property type="entry name" value="RNase_E/G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30001">
        <property type="entry name" value="PTHR30001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10150">
        <property type="entry name" value="RNase_E_G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00757">
        <property type="entry name" value="RNaseEG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="S1 motif" evidence="6">
        <location>
            <begin position="40"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV55539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="533" mass="60437" checksum="13EBE72011F84BAA" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRH6</accession>
    <name>A0A518IRH6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_16840</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="SSF88713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="370" mass="42519" checksum="B7F7018914704DEB" modified="2019-10-16" version="1">MDDVNQPDLSFRFAFDGPLGRVLQQHALDDIAAARLTWKFKAYYRLRPWIPIAMRQLLQRGRNRSLDAPDDWYLPTEFISDWQRAVSHDVATTPNHRTLHPWPDGFEVATVLTHDVETRAGVKLVSALASLEEEYGFRSAWNFVPYKYKIDAGLLDDLSSRGHEIGVHGYNHDGRLFESRRTFDWRKDRINEAIGNFKSTGFRAPMVHRNLDWLQGLDVDYDASCFDVDPFQAMPGGIGSPWPFIAGKFVELPYTLPQDHTLLVALGETTPQVWIDKLQYLRQIAGMAMLITHPDYLDTSRRLNIYRQFLEHLREQTDLWHALPRDVATWWRQRDQSTISAVDDSIEGPAAARGRVVAIDELFAATRCPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRK0</accession>
    <name>A0A518IRK0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_17050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043745">
        <property type="entry name" value="DUF5690"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18943">
        <property type="entry name" value="DUF5690"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="123"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="155"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="208"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="248"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="277"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="302"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="341"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="381"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="419" mass="45989" checksum="DA3478A9CD0B9CE9" modified="2019-10-16" version="1">MLWGSMAAFGTYFCMYAFRKPFTVIDYDDMTAWGWGYKTVAVAAQVFGYMVSKFLGIKILSELPAHRRAVSIIGLILFAEVALIGFGLVPAPYNIICLVLNGLPLGMVFGLVLGFLEGRKQTEALAAILCTSFILSDGVTKSVGKGLLEMGVPGFWMPATAGALFLLPMLFFVWMLRQVPPPSDADIAARSKRVPLTSKERRDFFSRYAWGLTPLLVMYLLVTIVRSVRSDFAPQIWESLGVTTTPELFSYSELWVGLGVTLANGAAMLVGDNYRGFKLALATCSIGFAILLMSTYGQHVGLISPFLFMVLIGVGLYLPYVATHTTIFERLIAMTRDRGNLVHLMYLADSIGYLGYVGVMLVKNVFQPGGDFMSFFRPACYVVGLVSLLCMIGCQFFFSLRASRQAPAPSPIPIEQPAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRS4</accession>
    <name>A0A518IRS4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Foldase protein PrsA</fullName>
            <ecNumber evidence="4">5.2.1.8</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">prsA</name>
        <name evidence="4" type="ORF">Mal33_17600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="5.2.1.8" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PPIase_dom_sf"/>
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        <property type="entry name" value="PPIase_PpiC"/>
    </dbReference>
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        <property type="entry name" value="PPIase_PpiC_CS"/>
    </dbReference>
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        <property type="entry name" value="Trigger_fact/SurA_dom_sf"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0413">Isomerase</keyword>
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    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021748330" evidence="2">
        <location>
            <begin position="24"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="domain" description="PpiC" evidence="3">
        <location>
            <begin position="163"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV55781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="309" mass="33783" checksum="D0C0559538B467B1" modified="2019-10-16" version="1" precursor="true">MIHCRVRLLSLLLACLCGLTATGQSQPETDAIAWIGDDPVLASEIDLLVHRRGLAATDLKANPTLRSALANVLVRRHLALASLRDQSGKAGAAIIDDAIQAWQQQVLASGKTLEEFAAQQQSDVAALQAEVAWLSLWNDYLRVRLNDANLQRFFETRSSLYDGTQADVSQIFLSDPAQLEALEKIADRIRGDEISFADAAAEHSQAGSADAGGRIGWIGADGDLPAVVAEAALMAESETLLPVVRSGLGLHLVYVHEKRNGDRSFADLTDHRRLRRDAADFLFEHLVDRGQTLHDVRWQEGQSERPLGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRV9</accession>
    <name>A0A518IRV9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">3-oxoacyl-[acyl-carrier-protein] synthase 3</fullName>
            <ecNumber evidence="3">2.3.1.180</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">fabH_2</name>
        <name evidence="3" type="ORF">Mal33_17900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.3.1.180" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033818">
        <property type="term" value="F:beta-ketoacyl-acyl-carrier-protein synthase III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013747">
        <property type="entry name" value="ACP_syn_III_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08541">
        <property type="entry name" value="ACP_syn_III_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thiolase_N" evidence="1">
        <location>
            <begin position="69"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="ACP_syn_III_C" evidence="2">
        <location>
            <begin position="258"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="373" mass="39555" checksum="433594731CD4758A" modified="2019-10-16" version="1">MQFENVCIESLGVHLPEEVWTSDEIERRLEPLYSRLRLPEGRLELMSSIAQRRVWPAGTLPSGPSIESCKSAISAAGIDPARVGCLIHASVCRDFLEPATASRVHHGAGLSPNCWVYDVSNACLGLLNGIVQIATLIEQGAIEAGIVVGTENSRPLLEATINNLNADESITRKTVKPAFASLTIGSGSCAVLLTHRRISQSGSRLEHAVSHAATDGHNLCRSDTDSAGANMAPLMDTDSERLLAAGVAAGAAGFEKLLADAKWDRADIDRTICHQVGGRHRALMLETLSLPPENDTAVFPWLGNTGSVALPLALAAAGQYQHVQPDQRIGLLGIGSGINCVMLGCKWQETRVAGNLPAVEPVMGQESLTAVEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IS05</accession>
    <name>A0A518IS05_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">NADH-quinone oxidoreductase subunit L</fullName>
            <ecNumber evidence="9">1.6.5.11</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">nuoL_2</name>
        <name evidence="9" type="ORF">Mal33_18430</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Membrane</location>
            <topology evidence="1 5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="1.6.5.11" evidence="9"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050136">
        <property type="term" value="F:NADH dehydrogenase (quinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001750">
        <property type="entry name" value="ND/Mrp_mem"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001516">
        <property type="entry name" value="Proton_antipo_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00361">
        <property type="entry name" value="Proton_antipo_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00662">
        <property type="entry name" value="Proton_antipo_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="75"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="111"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="163"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="214"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="249"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="284"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="341"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="373"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="414"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="466"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="domain" description="Proton_antipo_N" evidence="8">
        <location>
            <begin position="70"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="Proton_antipo_M" evidence="7">
        <location>
            <begin position="130"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV55864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="497" mass="52492" checksum="84339D6BBC5E56F8" modified="2019-10-16" version="1">MTPENLLILAMGLPLIGVGAVFLVGKLPNVREAASLTIAIALFGITCLLASHVFAGGRPEWHIGEMIPGFEIAFAVEPLGMLFALVASGLWILTTVYAAGYMRGNHESHQTRFFACFAAAIFAALAAAFSANLFTLFVAYEIMTISTYPLVTHHGTREARNGGRVYLGILLSTSVAFFMFAIAWTSNIAGTLDFRLGGILAEPLADGKITETQLGVLLGLFAFGIGKAALMPFHRWLPAAMVAPTPVSALLHAVAVVKVGVFSVLKVAVFIFGIDLLRTTGVSIWLAYVAAGTLVTASLVAMTKDSLKARLAYSTISQLAYISLGAALATPASVIGGGMHIAMHAVGKITLFFCAGAIYVATHKKNISEMQGLGRQMPFTFAAFLIASLSIIGLPPGGGVWSKWFLAVGTVETQHYLLTAALMVSSLLNIAYLIPIPIRAFMAPQETTADPHAAPAGIQEAPWMCVVPLCLTAALSIVLFFTAGSIYEVLLPLVSSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IS66</accession>
    <name>A0A518IS66_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Bifunctional protein Aas</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">aas</name>
        <name evidence="3" type="ORF">Mal33_19180</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PlsC" evidence="2">
        <location>
            <begin position="60"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="764" mass="84118" checksum="A8C651F4DB67FD08" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IS86</accession>
    <name>A0A518IS86_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 10">Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex</fullName>
            <ecNumber evidence="5 10">2.3.1.61</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">2-oxoglutarate dehydrogenase complex component E2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">sucB</name>
        <name evidence="14" type="ORF">Mal33_19360</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 10">E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>(R)-N(6)-dihydrolipoyl-L-lysyl-[2-oxoglutarate dehydrogenase complex component E2] + succinyl-CoA = (R)-N(6)-(S(8)-succinyldihydrolipoyl)-L-lysyl-[2-oxoglutarate dehydrogenase complex component E2] + CoA</text>
            <dbReference type="Rhea" id="RHEA:15213"/>
            <dbReference type="Rhea" id="RHEA-COMP:10581"/>
            <dbReference type="Rhea" id="RHEA-COMP:10582"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="ChEBI" id="CHEBI:83120"/>
            <dbReference type="EC" id="2.3.1.61"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
        <text evidence="10">Binds 1 lipoyl cofactor covalently.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 10">Amino-acid degradation; L-lysine degradation via saccharopine pathway; glutaryl-CoA from L-lysine: step 6/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the 2-oxoacid dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.61" evidence="5 10"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00868">
        <property type="reaction ID" value="UER00840"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045252">
        <property type="term" value="C:oxoglutarate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004149">
        <property type="term" value="F:dihydrolipoyllysine-residue succinyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033512">
        <property type="term" value="P:L-lysine catabolic process to acetyl-CoA via saccharopine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003016">
        <property type="entry name" value="2-oxoA_DH_lipoyl-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001078">
        <property type="entry name" value="2-oxoacid_DH_actylTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036625">
        <property type="entry name" value="E3-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004167">
        <property type="entry name" value="PSBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006255">
        <property type="entry name" value="SucB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00198">
        <property type="entry name" value="2-oxoacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02817">
        <property type="entry name" value="E3_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47005">
        <property type="entry name" value="SSF47005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01347">
        <property type="entry name" value="sucB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00189">
        <property type="entry name" value="LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51826">
        <property type="entry name" value="PSBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 14" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="9 10" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 10" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="12">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="Peripheral subunit-binding (PSBD)" evidence="13">
        <location>
            <begin position="103"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="77"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="149"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00019511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="QDV55957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="410" mass="44268" checksum="21144EA887609A99" modified="2019-10-16" version="1">MVEVKVPTVGESISEVQIGRWLKQQDEWVEADEDLVEIETEKASVQIPSPSAGYLRNITKQQDEFAKVGDVIAQIEAGEAPSGNGSASASAAAPSGESADDARVMPAAARLIAEHNLNPADIKATGPGGRLLKEDVLDHISGATISKVPAAAPKQPAAAPAKASEERPRTSLMTSGEHRAEEVKPLSMLRRTIAARLVEAQHNAALLTTFNEIDMEPVKELRSKYKDAFQKKHGVKLGFMSFFAKAAVEALRRFPAVNSEIRGNNIVYRHYHDIGIAIGGGKGLVVPILRNVEFMSFADVERAISDFADDAQANRLNPQDLDGGTFTISNGGIYGSLLSTPIVNPPQSGILGLHSIQDRPVAVNGEVVIRPMMYVALTYDHRVVDGREAVSFLRVIKDVLEDPARLFLEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISF1</accession>
    <name>A0A518ISF1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 7">Flagellar hook-associated protein 1</fullName>
            <shortName evidence="7">HAP1</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 10" type="primary">flgK</name>
        <name evidence="10" type="ORF">Mal33_19930</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Bacterial flagellum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2 7">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the flagella basal body rod proteins family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009424">
        <property type="term" value="C:bacterial-type flagellum hook"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044780">
        <property type="term" value="P:bacterial-type flagellum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001444">
        <property type="entry name" value="Flag_bb_rod_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019776">
        <property type="entry name" value="Flagellar_basal_body_rod_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010930">
        <property type="entry name" value="Flg_bb/hook_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002371">
        <property type="entry name" value="FlgK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30033">
        <property type="entry name" value="PTHR30033"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00460">
        <property type="entry name" value="Flg_bb_rod"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06429">
        <property type="entry name" value="Flg_bbr_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01005">
        <property type="entry name" value="FLGHOOKAP1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02492">
        <property type="entry name" value="flgK_ends"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00588">
        <property type="entry name" value="FLAGELLA_BB_ROD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="10" id="KW-0966">Cell projection</keyword>
    <keyword evidence="10" id="KW-0969">Cilium</keyword>
    <keyword evidence="10" id="KW-0282">Flagellum</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Flg_bb_rod" evidence="8">
        <location>
            <begin position="8"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="domain" description="Flg_bbr_C" evidence="9">
        <location>
            <begin position="498"/>
            <end position="563"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF06429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV56014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="564" mass="59340" checksum="15989F1D77C08C6F" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISI2</accession>
    <name>A0A518ISI2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Acyl-CoA_dh_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_20200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016627">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA_dh_N" evidence="1">
        <location>
            <begin position="26"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="365" mass="38391" checksum="20632789A7ECAC2D" modified="2019-10-16" version="1">MNQPADNAAVEIVQAPDSPAMDALCDRLQTLADQTDRSGEWPAAQLQLCAAAGVFRWFMPTTAGGFGWSDADQTRGYLRLAAADLTTTFIITQRMGACRRIEGCENETLQKRWLPPLLDGSQFATVGISHLTTSRRHLSTPVLRAEAVGDGYRLSGYSPWVTGGAHADVIVVGATLDDGRQLLAAVPTDRPGVLAAAGIPLVALSASATDRVDLQDVAIGPDDLIAGPIEDVMSQGVGAGTGGLQTSTLAIGLSKAAVDFLTAEAQQREALLPVAEQLQTEVRNLEVDLLSVASGNQVCSTSDLRGRANRLALRASQAALTAAKGAGFVQGHPAGRWCREALFFLVWSCPQPIANAHLCELAGIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISR6</accession>
    <name>A0A518ISR6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Inner membrane protein YrbG</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">yrbG_2</name>
        <name evidence="7" type="ORF">Mal33_20720</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1420.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004481">
        <property type="entry name" value="K/Na/Ca-exchanger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004837">
        <property type="entry name" value="NaCa_Exmemb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044880">
        <property type="entry name" value="NCX_ion-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10846">
        <property type="entry name" value="PTHR10846"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01699">
        <property type="entry name" value="Na_Ca_ex"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00367">
        <property type="entry name" value="TIGR00367"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="59"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="96"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="128"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="157"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="206"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="240"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="275"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="303"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="334"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="domain" description="Na_Ca_ex" evidence="6">
        <location>
            <begin position="27"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="Na_Ca_ex" evidence="6">
        <location>
            <begin position="206"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV56093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="353" mass="36952" checksum="21A18530BB326BB1" modified="2019-10-16" version="1">MLEAFLEHFFAFDLLTWLHTAPWILIALGLVVGVLMLGKSADVLVDEATELSLKLGMPRVIVGATIVSLGTTTPEAVVSVMAAIGGTPGLALGNAVGSIICDTGLILGVACLIAPIPLDRWLVNRQGMVQFGAGLLLIGMCVPWTRLGTMMTEGGVLPQWGGFMFLGLLAVYVLWSIHVAKSKGVSDEPSDDSGEPEAVRSTVGMVFMLLVATFFVVVSSEILISAAIETAARLNVPEGVIAATLVAFGTSLPELTIAVTASLKGRGELAIGNVIGADILNVLFVAGAAAAVTPVGLNAAPEFFRVQFPAMLAVLITFRVAIMCAKGDQLPRWAGGLLVGFYFAYLGFSFVMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IST6</accession>
    <name>A0A518IST6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC-2 family transporter protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Mal33_21190</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071586">
        <property type="term" value="P:CAAX-box protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032688">
        <property type="entry name" value="ABC2_membrane_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003675">
        <property type="entry name" value="Rce1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12679">
        <property type="entry name" value="ABC2_membrane_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02517">
        <property type="entry name" value="Rce1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="54"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="250"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="303"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="340"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="378"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="428"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="481"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="513"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="552"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="594"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="632"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="662"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="716"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV56140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="752" mass="81912" checksum="705881DC3AB454ED" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITE1</accession>
    <name>A0A518ITE1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Magnesium transporter MgtE</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Mal33_23220</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Acts as a magnesium transporter.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the SLC41A transporter family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015095">
        <property type="term" value="F:magnesium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.60.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006668">
        <property type="entry name" value="Mg_transptr_MgtE_intracell_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038076">
        <property type="entry name" value="MgtE_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006669">
        <property type="entry name" value="MgtE_transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006667">
        <property type="entry name" value="SLC41_membr_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036739">
        <property type="entry name" value="SLC41_membr_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43773">
        <property type="entry name" value="PTHR43773"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01769">
        <property type="entry name" value="MgtE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03448">
        <property type="entry name" value="MgtE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00924">
        <property type="entry name" value="MgtE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161093">
        <property type="entry name" value="SSF161093"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00400">
        <property type="entry name" value="mgtE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0129">CBS domain</keyword>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="286"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="315"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="360"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="386"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="425"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="8">
        <location>
            <begin position="136"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="8">
        <location>
            <begin position="202"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV56340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="453" mass="50303" checksum="352B20B71EB6DE7F" modified="2019-10-16" version="1">MVNTLFLPELREMLAESNDSDLAEFCTALHPVRTAEFMEGLTANEAWQVLQHADVALRAEIFSYLDEERQLEILEQEDPQRLADLVAEMPSDDRVDLIHELEDERANEILPLLPEAERRDIMRLKSHAEETAGALMTTDFVRLSASLTVREALDDLSRQAADHETIYYLYVVDEDHQLRGVVSGRQLIAAMGKPNTTMGELMDTDIVTVQIDEDQESVAEKVERYNLLAIPVVDEGRVLMGIITHDDVIDVLRDELTEDVQRIAAVAPLDEGYLRENILTLTWKRGIWLTVLFFAAMLTMLLLRHYDVELEKFIWLAWFIPLVISSGGNTGSQSATLVITALTSGDVKVGDWRTVARREVMMGVLLGGSLGTIGYIFALFVAPSAYAAITIPITVLLVISSGAIAGGLLPLLFKRLELDPALMSNPFVAGIVDILGIMIYINVARIVLSGVAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITM5</accession>
    <name>A0A518ITM5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">8-amino-7-ketopelargonate synthase</fullName>
            <ecNumber evidence="7">2.3.1.47</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">bioF_1</name>
        <name evidence="9" type="ORF">Mal33_24320</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 7">
            <text>6-carboxyhexanoyl-[ACP] + H(+) + L-alanine = (8S)-8-amino-7-oxononanoate + CO2 + holo-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:42288"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:9955"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78846"/>
            <dbReference type="ChEBI" id="CHEBI:149468"/>
            <dbReference type="EC" id="2.3.1.47"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 6 7">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Cofactor biosynthesis; biotin biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 7">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.47" evidence="7"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00078"/>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008710">
        <property type="term" value="F:8-amino-7-oxononanoate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009102">
        <property type="term" value="P:biotin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001917">
        <property type="entry name" value="Aminotrans_II_pyridoxalP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004723">
        <property type="entry name" value="AONS_Archaea/Proteobacteria"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00858">
        <property type="entry name" value="bioF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00599">
        <property type="entry name" value="AA_TRANSFER_CLASS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-0093">Biotin biosynthesis</keyword>
    <keyword evidence="6 7" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="8">
        <location>
            <begin position="42"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="6">
        <location>
            <position position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR604723-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV56442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="384" mass="41346" checksum="D14355F37C16C0E5" modified="2019-10-16" version="1">MDARFDWIAKRLKQFDGEGATRRLAPRQSQPGRMVIQSDGINLVNFGSNDYLGLAAEQSTQRPEHGSMGSGASALVTGFSPVALQLQQRLAQWEATESCVLFPTGFAANLGTISALAEAGDLILSDAANHASIIDGCRLSKAQRFVYPHNDTSAVAALLETHRRRFARVFIVTDSVFSMDGDFAPLETLCDLADRYDSILIADEAHGTGVFGDSGSGLCEHLGVKHRVPIRIGTLSKAIGAMGGFVVGPQVVTDYLVNRARSMIYSTALPPALVSAALANVIQIQEEPQRRAQLFELSQRLRDRVASKWRLPPMSTPGQIVPFVVGSNEEAVRASQRLADAGLFVPAIRPPTVPAGTARLRVSLSSSHSDEEIDRLAEALCGLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ITW5</accession>
    <name>A0A518ITW5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Helix-turn-helix domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_25180</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041657">
        <property type="entry name" value="HTH_17"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12728">
        <property type="entry name" value="HTH_17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_17" evidence="1">
        <location>
            <begin position="79"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="134" mass="15181" checksum="B1019802DAB4002D" modified="2019-10-16" version="1">MAVDTTVSRYRAALLQEAELEKRLIDARTERQICEKMLALRGSRGDDKSANRVHAEEVIAKHADRLEPSDWEMLDSEFCTTGEAARYTGLSATSIKRYCDRGDFATKRSSMKRRLISTVSLVEFMINGKTEETS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IU96</accession>
    <name>A0A518IU96_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Demethylrebeccamycin-D-glucose O-methyltransferase</fullName>
            <ecNumber evidence="2">2.1.1.164</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rebM</name>
        <name evidence="2" type="ORF">Mal33_26330</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.1.1.164" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102082">
        <property type="term" value="F:demethylrebeccamycin--D-glucose O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="1">
        <location>
            <begin position="77"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="288" mass="31785" checksum="C998A418F1465CC3" modified="2019-10-16" version="1">MNASESPNPPYFDVLLDRIASGDREAVTAFGRHVHWGLWDSPAAADGSAADYLQAAERMCQRICDAAKIQPPARIADVGCGFGGTIASLNERYQSLAMTGINIDPRQLQRAEEQVVPAADNQIQWTCADAASLPLDDAAFDAVLAVECIFHFDRPRFFAEASRILRPGGVLSLSDFVPQPQMADFMTGGAGAMSEAIRWTYGDVDMSCSLDGYEQLAAENGMRLLACEDVTEQTLPTYDFLCEGAQRWHDRHHAELFLQATGWLRKASRKKLIRYLILSFEKLGDRSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUF2</accession>
    <name>A0A518IUF2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Serine/threonine-protein kinase PrkC</fullName>
            <ecNumber evidence="4">2.7.11.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">prkC_8</name>
        <name evidence="4" type="ORF">Mal33_27050</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.11.1" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="3">
        <location>
            <begin position="156"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="476"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV56707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1426" mass="157277" checksum="5B9D98E8F64E4789" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUG4</accession>
    <name>A0A518IUG4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_27340</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV56736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="167" mass="19090" checksum="9D43E3736ACB5516" modified="2019-10-16" version="1">MTGPQLAILHHGDCCPGDAAYVEDPIRSPSLRRTQRWQPKQTMTKKQRIPHKFQPWIAVRKKYRLTDAQVQMARELGLSPKRFSNYADRKDQPWKLPLPEFIEALYEKQFGRVAPEVVLTIEAMAAEHQARREAKKLAKQEALAQEESQTEDAAATDEPASPEADDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUJ7</accession>
    <name>A0A518IUJ7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_27600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2310.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035093">
        <property type="entry name" value="RelE/ParE_toxin_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV56761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="106" mass="12214" checksum="E3763B1CA359FF92" modified="2019-10-16" version="1">MSFRLNVTNQARDDITRNANWWAENHSLDEALTWYDSVYDQLNELLAFPESHGLAAENDAFPYELREKLVGGKKRTYRAIFTIEGAEIRVLTIRRAAQRAITPDDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IUM8</accession>
    <name>A0A518IUM8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">8-amino-7-oxononanoate synthase</fullName>
            <ecNumber evidence="3">2.3.1.47</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">bioF_2</name>
        <name evidence="3" type="ORF">Mal33_27940</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.3.1.47" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008710">
        <property type="term" value="F:8-amino-7-oxononanoate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="2">
        <location>
            <begin position="89"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="448" mass="50096" checksum="E2344C40AFA8F8FC" modified="2019-10-16" version="1">MSVKSSLERLKMQIRRESSDSEEDNAAKKPPQSRGEVKASPAFYQFDKFPEYKEFTTMEWYLDKEKYPRTQFLKRLSVSDATVNLEGREMINFSTYNYLGLAGDARVKEAAKRAVDTFGTSTGSGRSITGEIDLHRAFENEICEVLGTEDAVLSVGGYSTNTFAIGYLCRNKDLILYDELIHNSALAGCKMTAARRIGFPHNDYEALEALLAANRGKFERVLILVEGVYSMDGDIPDLPRLIEIKRRYKALLMVDEAHSFGIIGPNGLGVTDYFDFDPHDVDIFFGSLSKSFGTCGGYIAGPKPLIAMLKYFAPGVLLYGAAPTPANTAAGLESLRIMRAEPERARRLVDNARHFIQRAKAAGLDTYNSHDSAVVPLMCRDSELALWLSMALFGQGICAYPMLHPIVPRDKSRLRFFINTFHTYEQLDYTIQCIVDNLRVAPKSKGVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IV11</accession>
    <name>A0A518IV11_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_29280</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022190291" evidence="2">
        <location>
            <begin position="23"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="188"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="225" mass="23373" checksum="555711DF8CAF4F6D" modified="2019-10-16" version="1" precursor="true">MRLLYCTLALSLPLLVGSSAFAQDESSVVQELPVATPTGDEDLPVAKPTASGDDPVATAVSSPGALATRPLSVTITLANQSVIRGTLTDTTEVQMKTGFGELMIPLSEVAGIRFASQEDTSTTIVMLNGDSVTGATDVKRLTIDTEWGAAQVNGPSIASILLVPNLQWSSIAGLNGKRWYLTESNNVPTNANSGGNRSASPTPVPSNSFPSNNGTLSAPPTFRSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IV63</accession>
    <name>A0A518IV63_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Preprotein translocase subunit SecA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Mal33_29710</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017038">
        <property type="term" value="P:protein import"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18803">
        <property type="entry name" value="SF2_C_secA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000185">
        <property type="entry name" value="SecA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020937">
        <property type="entry name" value="SecA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011115">
        <property type="entry name" value="SecA_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014018">
        <property type="entry name" value="SecA_motor_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011130">
        <property type="entry name" value="SecA_preprotein_X-link_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044722">
        <property type="entry name" value="SecA_SF2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036670">
        <property type="entry name" value="SecA_X-link_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30612">
        <property type="entry name" value="PTHR30612"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07517">
        <property type="entry name" value="SecA_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01043">
        <property type="entry name" value="SecA_PP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00906">
        <property type="entry name" value="SECA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00957">
        <property type="entry name" value="SecA_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00958">
        <property type="entry name" value="SecA_PP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="2"/>
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        <property type="match status" value="1"/>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SECA_MOTOR_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-1278">Translocase</keyword>
    <keyword evidence="8" id="KW-0811">Translocation</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
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        <location>
            <begin position="1"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="10">
        <location>
            <begin position="64"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="11">
        <location>
            <begin position="404"/>
            <end position="552"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="QDV56970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="607" mass="65954" checksum="8DA1F250892F3E47" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IV94</accession>
    <name>A0A518IV94_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_30070</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021727857" evidence="1">
        <location>
            <begin position="28"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="258" mass="27734" checksum="7879761FFB62EF71" modified="2019-10-16" version="1" precursor="true">MTRNVTKFALTLTLIATCLVQSSTARGASPVEQMLDTVANNQQFAYILFYRNNDAATQSMHGVLQSTFAERRDAAILPVQITDVAERDLVKRFDATRLPMPAVAVLAPNGAVCSVFPQRVTENQLTSAIVSPGQAKCLKALQDKKIVLLCAQPTAGAAIPMGVRQFMADSLYQDRSTVVTVEANDPGEAKFLKQLRVRTDQPTSVVAFMAPPGVMIGIFNGSVTHSTLAEKLAAAGKCCDDENCKHHKSAGASQPARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVA7</accession>
    <name>A0A518IVA7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcriptional regulator MntR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">mntR</name>
        <name evidence="6" type="ORF">Mal33_30150</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DtxR/MntR family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046914">
        <property type="term" value="F:transition metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.60.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001367">
        <property type="entry name" value="Fe_dep_repressor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036421">
        <property type="entry name" value="Fe_dep_repressor_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022687">
        <property type="entry name" value="HTH_DTXR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022689">
        <property type="entry name" value="Iron_dep_repressor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02742">
        <property type="entry name" value="Fe_dep_repr_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01325">
        <property type="entry name" value="Fe_dep_repress"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00529">
        <property type="entry name" value="HTH_DTXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47979">
        <property type="entry name" value="SSF47979"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50944">
        <property type="entry name" value="HTH_DTXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH dtxR-type" evidence="5">
        <location>
            <begin position="14"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV57014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="135" mass="14993" checksum="30AF1B4D07A23D05" modified="2019-10-16" version="1">MPSKTHQRTRSDHASEVAEDYVEAIADAIAQRGVCRAVDLVNQFAVTHATVNNTIGRLQRDGLVHTEPYQPIELTATGKRLATQSRKRHEIVEAFLRRLGVSEQTAAADTEGIEHHVSKETLAAMKRVLTKGWPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVB2</accession>
    <name>A0A518IVB2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Matrixin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Mal33_30310</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031012">
        <property type="term" value="C:extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002105">
        <property type="entry name" value="Dockerin_1_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036439">
        <property type="entry name" value="Dockerin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001818">
        <property type="entry name" value="Pept_M10_metallopeptidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021190">
        <property type="entry name" value="Pept_M10A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006026">
        <property type="entry name" value="Peptidase_Metallo"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00404">
        <property type="entry name" value="Dockerin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00413">
        <property type="entry name" value="Peptidase_M10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00138">
        <property type="entry name" value="MATRIXIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00235">
        <property type="entry name" value="ZnMc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="SSF47473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63446">
        <property type="entry name" value="SSF63446"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="ZnMc" evidence="6">
        <location>
            <begin position="35"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="204"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="344"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="206"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="344"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV57030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="598" mass="64266" checksum="84AE2B17C3B4E6D2" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVB3</accession>
    <name>A0A518IVB3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PINc domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_30280</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002850">
        <property type="entry name" value="PIN_toxin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34610">
        <property type="entry name" value="PTHR34610"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13470">
        <property type="entry name" value="PIN_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PINc" evidence="1">
        <location>
            <begin position="2"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="123" mass="13902" checksum="4E861052B4E88DB2" modified="2019-10-16" version="1">MAYRVLMAVLNRRVPLMLTEGIIAEYTDVLSRPTVRKLTGLTAKQNSDLILELISLSHQTQLRFSWRPNLSDEADNKFIEAAVAATALIITYNVRDFDCADLVKHGWDVMTPVEFSTLYDLGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVI9</accession>
    <name>A0A518IVI9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_31050</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027839">
        <property type="entry name" value="DUF4432"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14486">
        <property type="entry name" value="DUF4432"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV57104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="388" mass="42103" checksum="C45BFDD01E1D07C5" modified="2019-10-16" version="1">MATDFQNPAAPRTLPAIDWHPPGEGCLAAMESTEGQINLKYGTIASGRGAGIEVVQIDTGPMQVTLLPTRGMAIWQVICDGIPFKWNSPVDGPVHPSLVPVHDPGGIGWLEGFDELLVRCGLVSNGAPEFEESGRLRYPLHGRIANTPAERVWSEEVEGRCVVAGETHEKRLFFNNLTLTTRVSVAPGGREIEIEDTVSNHGSQPAETQMLYHINVGAPVLEEGAKLLLAYEELSPRNDHAASDIPTWDRYPGPKSGYQEQVHLFRVKSDAAGSTAMMLQSPGGQQGFGLSYDTSTLPYFIVWKNTAAHEDGYVTGLEPATNFPNPRSFEGERGRVATIPAGGSITHRVNLHPLVGQQNVDSFAEKVHALQGNDKPTVHQQPNPDWAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IVK3</accession>
    <name>A0A518IVK3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Tetratricopeptide repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_31130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013105">
        <property type="entry name" value="TPR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07719">
        <property type="entry name" value="TPR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="61"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="189" mass="21819" checksum="2E5B818B69B0BF09" modified="2019-10-16" version="1">MSVSKLRYYQNYRSLRQAQGLLELISCNDDLWGLDPEIKRRLARRALAMLQGARPRGHRRAAWYYLRGRAWSMLGKYHRGIRTFRRAAKLDPHHIATYLSLAWCLKRVDRLEQSISILNHAIARAPHHPLVRYNQACYLSLAGQPQLAAMELSIALELKPDLRSKVAREADFDPIRNHPAFDAALQVVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IW91</accession>
    <name>A0A518IW91_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_33580</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021790272" evidence="2">
        <location>
            <begin position="25"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="129" mass="14304" checksum="3F4B3D9298B1BC33" modified="2019-10-16" version="1" precursor="true">MFPKPQLSVFLILAILSVASGCHCFPSVRYRNPHAADYETACTCGRGDCLECRDREEKTKKVPWPQFHSVPTRPVFEGNPATQMVPYCEPQNEVVLPPLRPVPPPGAVETLAPPLEMQEETPPGTNYSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWG8</accession>
    <name>A0A518IWG8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Dipeptidyl-peptidase</fullName>
            <ecNumber evidence="2">3.4.14.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_34050</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the removal of dipeptides from the N-terminus of oligopeptides.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the peptidase S46 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.14.-" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008239">
        <property type="term" value="F:dipeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070009">
        <property type="term" value="F:serine-type aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043171">
        <property type="term" value="P:peptide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019500">
        <property type="entry name" value="Pep_S46"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38469">
        <property type="entry name" value="PTHR38469"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10459">
        <property type="entry name" value="Peptidase_S46"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0720">Serine protease</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023025416" description="Dipeptidyl-peptidase" evidence="2">
        <location>
            <begin position="19"/>
            <end position="676"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU366067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="676" mass="75843" checksum="BB3181C66937C926" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWK1</accession>
    <name>A0A518IWK1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Lactate utilization protein B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">lutB</name>
        <name evidence="9" type="ORF">Mal33_34800</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019516">
        <property type="term" value="P:lactate oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004452">
        <property type="entry name" value="4Fe-4S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024185">
        <property type="entry name" value="FTHF_cligase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003741">
        <property type="entry name" value="LUD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47153">
        <property type="entry name" value="PTHR47153"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13183">
        <property type="entry name" value="Fer4_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02589">
        <property type="entry name" value="LUD_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="8">
        <location>
            <begin position="295"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="8">
        <location>
            <begin position="345"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="449"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV57470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="474" mass="52499" checksum="2A81439EBAB4314F" modified="2019-10-16" version="1">MATVSEHPEKAAAYIADRSRSRWHDGALWFVRSKRDRMAHSLPEWEQLRTTASQIKAHTIANLPEILQQFEANAKARGVHVHWAADAQEHNEIVLEIVRKQNATRVVKSKSMLTEECHLNPHLEANGIEVIDTDLGERIVQMRGERPSHIVLPAIHIKKEEVGETFAKYLGTEPGASDPQYLTEAARQHLRSKFLEAEVGITGVNFAIAETGGFVVCTNEGNADLGASLPRVHIACMGIEKLIPRLVDLSVFVRLLARSATGQPITTYTSHFHGPRPGCELHIVLVDNGRSRIRDSDEFRSALGCIRCGACMNTCPVFRRSGGHSYDAVVPGPIGSVLSPAADTKQHRSLPYACSLCGSCTDVCPVKIPLHHQLLTWRQQIASQGLLPVSKTSAMRAGSMLFQHPRIYALAGALGRRALRWLPKSWIYNRANPWGLDRDLPEPPVESFRSWWQTNRQGTSVDEGTQSKGAKNGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWL0</accession>
    <name>A0A518IWL0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 8">UDP-glucose 4-epimerase</fullName>
            <ecNumber evidence="5 8">5.1.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">galE</name>
        <name evidence="10" type="ORF">Mal33_34880</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>UDP-alpha-D-glucose = UDP-alpha-D-galactose</text>
            <dbReference type="Rhea" id="RHEA:22168"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="ChEBI" id="CHEBI:66914"/>
            <dbReference type="EC" id="5.1.3.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 8">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 8">Carbohydrate metabolism; galactose metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 8">Belongs to the NAD(P)-dependent epimerase/dehydratase family.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.2" evidence="5 8"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00214"/>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003978">
        <property type="term" value="F:UDP-glucose 4-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006012">
        <property type="term" value="P:galactose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd05247">
        <property type="entry name" value="UDP_G4E_1_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005886">
        <property type="entry name" value="UDP_G4E"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01179">
        <property type="entry name" value="galE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="8 10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7 8" id="KW-0520">NAD</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="9">
        <location>
            <begin position="4"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00018569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV57478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="340" mass="37476" checksum="4F8F1B13745612E0" modified="2019-10-16" version="1">MRILVTGGAGYIGSHTCVELLQAGHELVVVDDLSNSKRESLRRVQQLAGKTLEFHELSLLDRDALTRVLAAADFDAVIHFAAFKAVGESVAKPLEYYQNNVTGTINLMDAMRSCGCKNLVYSSSCTVYGEPQQRPVTEDHPVAQAESPYGWTKLMTEQIMRDVYVSDPSWNFALLRYFNPVGAHPSGDIGEDPNGIPNNLMPFITQVALGKHEKLNVFGGDYDTPDGTCIRDYIHVVDLALAHVKAVEKVGKEEGIFTYNLGTGTGSSVLQVIAAFREATGIDLPYEIVDRRAGDVIVAYADPSRAERELGWKATRNLLDMCRDGWNWQHKNPEGMVEAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWW8</accession>
    <name>A0A518IWW8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">30S ribosomal protein S2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">rpsB</name>
        <name evidence="7" type="ORF">Mal33_35940</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uS2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01425">
        <property type="entry name" value="RPS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00291_B">
        <property type="entry name" value="Ribosomal_S2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001865">
        <property type="entry name" value="Ribosomal_S2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005706">
        <property type="entry name" value="Ribosomal_S2_bac/mit/plastid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018130">
        <property type="entry name" value="Ribosomal_S2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023591">
        <property type="entry name" value="Ribosomal_S2_flav_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12534">
        <property type="entry name" value="PTHR12534"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00318">
        <property type="entry name" value="Ribosomal_S2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00395">
        <property type="entry name" value="RIBOSOMALS2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52313">
        <property type="entry name" value="SSF52313"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01011">
        <property type="entry name" value="rpsB_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00962">
        <property type="entry name" value="RIBOSOMAL_S2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="250"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV57583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="280" mass="31424" checksum="A73AA0AC29CBF3F5" modified="2019-10-16" version="1">MLPWTTRIRQTPASLASRTPVLTLEKKNSMSNSIVKDMIEAGVHFGHRTSLWNPKMAPYIFGRKNQVHILDIRETLRGMLRAKKYLSQVAAGGSLILFVGTKRQAGEAIEKEALRCGMPFVSERWLGGTLTNFRTIRSRLTRLEELEKLRDNDQMDMYSKKMQSSLNREHRKMYRNLNGLRTMNRIPECLVIIDPGKERNAIREAKRLGITTIALIDSDSDPDLVDLPIPGNDDGIRSIELIVRQLADAVREGKGESASEEKDSAPAPAVETMAPAPSTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IWY5</accession>
    <name>A0A518IWY5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">tRNA (Mo5U34)-methyltransferase</fullName>
            <ecNumber evidence="3">2.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">cmoB</name>
        <name evidence="3" type="ORF">Mal33_36160</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016765">
        <property type="term" value="F:transferase activity, transferring alkyl or aryl (other than methyl) groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002098">
        <property type="term" value="P:tRNA wobble uridine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01590">
        <property type="entry name" value="tRNA_carboxymethyltr_CmoB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010017">
        <property type="entry name" value="CmoB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027555">
        <property type="entry name" value="Mo5U34_MeTrfas-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08003">
        <property type="entry name" value="Methyltransf_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00452">
        <property type="entry name" value="TIGR00452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0819">tRNA processing</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="321" mass="36135" checksum="35F3047483FB0139" modified="2019-10-16" version="1">MMLGIEGLLAELESEGHAGWAETLRQRAREFEHDAAHGLWPQWTQAICDLPAVESVTADFGLPAVTLSGEISPADQQRLREQLRLFHPWRKGPFDLFGIAIDTEWRSDWKWARVAPHLDLRDASVLDVGCGNGYYGWRMLAAGARRVIGLDPFPLYIAQHRVVEHYVGGSAAHVLPGTDADLPKRLEAFDVAFSMGVLYHRTSPIDHLKSMLQALRPGGKLVLETLIIDHPDSQVLIPEGRYAKMRNVWFIPSLTMLERFLSRCGFRDIEVVDVCVTTTEEQRRTEWMEFESLSDFLSPDQTTTIEGHPLPTRATVVASRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IX24</accession>
    <name>A0A518IX24_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Flagellar basal body P-ring protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Mal33_36380</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Bacterial flagellum basal body</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009428">
        <property type="term" value="C:bacterial-type flagellum basal body, distal rod, P ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030288">
        <property type="term" value="C:outer membrane-bounded periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001782">
        <property type="entry name" value="Flag_FlgI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004155">
        <property type="entry name" value="PBS_lyase_HEAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30381">
        <property type="entry name" value="PTHR30381"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02119">
        <property type="entry name" value="FlgI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00567">
        <property type="entry name" value="EZ_HEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="6" id="KW-0966">Cell projection</keyword>
    <keyword evidence="6" id="KW-0969">Cilium</keyword>
    <keyword evidence="6" id="KW-0282">Flagellum</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="551"/>
            <end position="585"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV57625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="585" mass="64127" checksum="4ED9B5034CD8EFFB" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IX65</accession>
    <name>A0A518IX65_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Perchlorate reductase subunit gamma</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">pcrC</name>
        <name evidence="2" type="ORF">Mal33_36870</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023155">
        <property type="entry name" value="Cyt_c-552/4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036280">
        <property type="entry name" value="Multihaem_cyt_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13435">
        <property type="entry name" value="Cytochrome_C554"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48695">
        <property type="entry name" value="SSF48695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome_C554" evidence="1">
        <location>
            <begin position="55"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="351" mass="38529" checksum="786FDD3BD7848876" modified="2019-10-16" version="1">MLFASLCHKRVVFVGVIVLFVVAGAVFGTTRGDQTGHVPPAITPMDPNLVLGYSTCAKCHPNEIEVWKGTPHYATFEELHRRPEAKQIAQKLGVSSIKYDGRCISCHYTQKTENGEVSAISGISCESCHGPAKNWIDLHYNYGGAGITRESESKEHREKRIADSIAAGMRNPHNIYTMAQSCMKCHTVPDEELVNVGGHSSGSLDFEMVSWSEGMVRHRFLAGGGTHNAKHTAEELNLLFVSGMIADLEFSLRATSNATSKSTYGYTVAKRASAVAKRLASVYKKTQIPLLREIIETYMAVPLSINNADALNEAADKIAKLGYQFAEEHTGAELTAIQPYVPGEERWLQQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXB6</accession>
    <name>A0A518IXB6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_37460</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="328"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="422" mass="46943" checksum="24892BD525EC8E89" modified="2019-10-16" version="1">MRRSWGPWGLLVLVAIVYAIYVMLSSPHKLTTPYGYSYSHQGTKSINGVAAFRKMYDLRGWESRTLKRLSRSAGRLDAIVWFPDADQVPSMEATRWLDQWLAEAPRTLVYVVRGLQSTESRYWQQALSDAAPDQRLEYRRRQVRALTTAAEPTFGTVAAPAVTSYSNGWFTADFHPHYTTAKDFSGPWADQIDPLPQRLTTRATIRPFDIDTDSQFSTGTFRSETVDEDDPPSVELEPLLRSADDDIVAARLTSEMWPDSQVLVLCSGECLMNLPLSDSVNRVFADHLVQVSGSPGEIGFLRTDLMGARVGSDSDDDLAAGMELLTQWPLSMTTMHVVLLGFVAILALLPIFGRPRRLPPPPTGDFGEHVAAVAELLQRSGDTDYARQRISEYFVQVRGEESGPWVLPSASTANEKLKGEAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXG1</accession>
    <name>A0A518IXG1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Wide host range VirA protein</fullName>
            <ecNumber evidence="3">2.7.13.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">virA</name>
        <name evidence="3" type="ORF">Mal33_37870</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.13.3" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="2">
        <location>
            <begin position="38"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="259" mass="27891" checksum="EB48F5F897CC0B3F" modified="2019-10-16" version="1">MTSTQTDHALSDQEKIAYLTHQLQQSQALASLGELTGTATHEFNNVLMTILNYAKLGIRHKDEATRDKALTKILAAAERAAKISQTILATARNRSDDFEPTDLASIIEDSLMLLERELRQYRVSVETDLQDVPAARANGNQIQRVLLNLVINARQAMPEGGTISIGLKTNAEANEVLLTVRDSGSGIPQDQLPNIFEPFFSTKSGPDASGKGGTGLGLSACRDIIQEHGGRIRVESTVGRGTAFIIRLPVASKSESAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXK8</accession>
    <name>A0A518IXK8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Na+/Pi-cotransporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Mal33_38380</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015114">
        <property type="term" value="F:phosphate ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005436">
        <property type="term" value="F:sodium:phosphate symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044341">
        <property type="term" value="P:sodium-dependent phosphate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003841">
        <property type="entry name" value="Na/Pi_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030147">
        <property type="entry name" value="NptA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10010">
        <property type="entry name" value="PTHR10010"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10010:SF46">
        <property type="entry name" value="PTHR10010:SF46"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02690">
        <property type="entry name" value="Na_Pi_cotrans"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="22"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="204"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="286"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="320"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="359"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV57823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="383" mass="39507" checksum="4A73849F5638D639" modified="2019-10-16" version="1">MDIAVPEEAAEAASNQSVWRQWLMVVCLVYLLICAVGLIGSGFKTATGSQAKQMFEFATNPFAGLVVGTVATALIQSSSTVTSIIVGLVAGGLPVSVAVPMVMGANIGTSITNTIVSLGHVREKKEFARAFSAATVHDFFNLLAVVIFLPLEMATGFLEKIGSGLAGIFVVGDASMGGLNFVKAATTPVVVFFKDGVAGMGTTAGGIVLILCGIVLIFLSIHFVGTLLKTLMVGKAKELLHSAIGKGPVSGICSGTLVTVLVQSSSTTTSLMVPLAGSGAFGLKQIYPFTLGANIGTCITALLAATAVDGNSAAALQIAFIHLTYNVLGVLFIFGVPMLRYLPVKAAEWLGETASENKLVALAYILSVFFVIPGMFLGVTSML</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IXV4</accession>
    <name>A0A518IXV4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sirohydrochlorin cobaltochelatase</fullName>
            <ecNumber evidence="3">4.99.1.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">cbiX</name>
        <name evidence="3" type="ORF">Mal33_39300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="4.99.1.3" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016852">
        <property type="term" value="F:sirohydrochlorin cobaltochelatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002762">
        <property type="entry name" value="CbiX-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01903">
        <property type="entry name" value="CbiX"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0456">Lyase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV57914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="258" mass="27938" checksum="5C1C50BCFE5838CA" modified="2019-10-16" version="1">MQSCTRPGYLLVGHGTRDLDGTKEFLQLGEVLGQLLAPAPVEACFLELQQPTIGEAWQRMVASNVDGIYAVPLLLFAAGHAKRDIPEELQAACDAAIGGSRGLPFVQTPPLQSHPKLLELSAIRAQQAIDVAGGVDLARTALVMVGRGSLDDGATVEMYRFSELRGQSLRPAVVRTGFVAMARPDLASVLDEVAQLPEIDTIVVQPHLLFQGDLNQRVMQMIDAAADRHRNRRWIAVDRLGPDPRLAQALIELAAEID</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IY18</accession>
    <name>A0A518IY18_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphoenolpyruvate:glucose-phosphotransferase regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_39980</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV57982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010384">
        <property type="entry name" value="MtfA_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06167">
        <property type="entry name" value="Peptidase_M90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022062451" evidence="1">
        <location>
            <begin position="29"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV57982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="258" mass="29180" checksum="3E1A1471EF30AF3B" modified="2019-10-16" version="1" precursor="true">MSISAIKTHSPASLCLLISLAVGLPAAAVEKPQQPATATPAQRYAARSLSGWTIQIRRELLEPENRAATDQALELLTIQLNEIRRVVPSAALKQLQQVTLWFSPQYPGIPPRAEYHPSGDWLRANGRDPAMARGVEFTNIRIFAAETRRMPNFALHELAHAYHHRDLPDGFQNEPLRSAFEKAKASGGYDRVERQDSEGNKRFDRAYALTSPQEYFAETTEAFFTRNDFFPFDRKELQQHDPEVCQLLTKLWGVQPTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYL3</accession>
    <name>A0A518IYL3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_42000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="97" mass="10388" checksum="DF8E6A3504057BD2" modified="2019-10-16" version="1">MIDPSLFEYIRCPVTQSTLVVAADDLIQQINQRVAAGEARNRIDRPVQRPLDSGLVNADGTLIYPVWADIPTLIPDEAIPIAAATAGAETTETDASV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IYM2</accession>
    <name>A0A518IYM2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">2,5-diketo-D-gluconic acid reductase A</fullName>
            <ecNumber evidence="5">1.1.1.274</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">dkgA</name>
        <name evidence="5" type="ORF">Mal33_42030</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.1.274" evidence="5"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050580">
        <property type="term" value="F:2,5-didehydrogluconate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018170">
        <property type="entry name" value="Aldo/ket_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000097">
        <property type="entry name" value="AKR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00798">
        <property type="entry name" value="ALDOKETO_REDUCTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00062">
        <property type="entry name" value="ALDOKETO_REDUCTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00063">
        <property type="entry name" value="ALDOKETO_REDUCTASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="4">
        <location>
            <begin position="4"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="37"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Lowers pKa of active site Tyr" evidence="3">
        <location>
            <position position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV58186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="314" mass="35438" checksum="CE6E502A77434209" modified="2019-10-16" version="1">MPVLGLGMWKIPNDQCASLVQAAAEVGYRHFDSACDYGNEREVGDGLRGVIDSGVCRREDLWVTSKLWNTFHRSEHVEAACRKTLDDLQLDYLDLYLIHFPIPLRYVSPEQRYPPGWFFDPEAAEPKMEIDRVSVAETWAAMEQLKQSGLVKEIGVCNFNIALLRDMLAYANDPPAVLQVETHPYLTQEKLFQFCREEQIAYTAFSPLGALSYHEIGMADGSDSLLQIEPIQSIAAAHDRSPAQVLLRWGVQRGTAVIPKTSKTERLAENFSLFDFSLSDAEMATIDGLNRNQRYNDPGVFCQAAFNTFCPIYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZ60</accession>
    <name>A0A518IZ60_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_43920</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="47" mass="5389" checksum="2B29DA792D8E4AC8" modified="2019-10-16" version="1">MRGEGNQENVEIQEKAKASVKTIFFRTNIYFFKTYLICSLIPACQTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZE6</accession>
    <name>A0A518IZE6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Chaperonin GroEL</fullName>
            <ecNumber evidence="6">5.6.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">60 kDa chaperonin</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Chaperonin-60</fullName>
            <shortName evidence="6">Cpn60</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">groL_1</name>
        <name evidence="6" type="synonym">groEL</name>
        <name evidence="6" type="synonym">groL</name>
        <name evidence="9" type="ORF">Mal33_44870</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 8">Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6 8">Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the chaperonin (HSP60) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="5.6.1.7" evidence="6"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042026">
        <property type="term" value="P:protein refolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03344">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00600">
        <property type="entry name" value="CH60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018370">
        <property type="entry name" value="Chaperonin_Cpn60_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001844">
        <property type="entry name" value="Cpn60/GroEL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00298">
        <property type="entry name" value="CHAPERONIN60"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="SSF48592"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="SSF52029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="SSF54849"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02348">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00296">
        <property type="entry name" value="CHAPERONINS_CPN60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="29"/>
            <end position="32"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="86"/>
            <end position="90"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="414"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="495"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV58464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="539" mass="57325" checksum="CF860386F862E8E7" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZI1</accession>
    <name>A0A518IZI1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Phosphoribosylaminoimidazole-succinocarboxamide synthase</fullName>
            <ecNumber evidence="8">6.3.2.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">SAICAR synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 10" type="primary">purC</name>
        <name evidence="10" type="ORF">Mal33_45250</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + ATP + L-aspartate = (2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate + ADP + 2 H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:22628"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58443"/>
            <dbReference type="ChEBI" id="CHEBI:77657"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.6"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the SAICAR synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.6" evidence="8"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00131"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004639">
        <property type="term" value="F:phosphoribosylaminoimidazolesuccinocarboxamide synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00137">
        <property type="entry name" value="SAICAR_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028923">
        <property type="entry name" value="SAICAR_synt/ADE2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001636">
        <property type="entry name" value="SAICAR_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018236">
        <property type="entry name" value="SAICAR_synthetase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01259">
        <property type="entry name" value="SAICAR_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00081">
        <property type="entry name" value="purC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01057">
        <property type="entry name" value="SAICAR_SYNTHETASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 8 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAICAR_synt" evidence="9">
        <location>
            <begin position="26"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QDV58502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="297" mass="32964" checksum="745B8D02E72777B1" modified="2019-10-16" version="1">MTSNDPFEFDSNGALLRTHLPLPGQSGKVRDVYDLGDSLLIVSTDRISAFDWILPNGIPNKGSILTAMSRFWFDHLQVANHLISCEVPQQVIDLGIDASVLADRIMVVRKAQVVPFECVIRGFIEGSGWAEYQQSGAICGIDLPAGLRQCDRLPEPIFTPATKAETGHDENVSTEVMSAAIGAEQTELLRRLSLQVYTTAADHAAERGILIADTKFEWGLVDGEVILIDEVLTPDSSRFWPKSSYEPGHSQPSFDKQYVREWLSQTDWDRNSPPPILPANVVQRTGEKYREALDILT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZN4</accession>
    <name>A0A518IZN4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Gluconolactonase</fullName>
            <ecNumber evidence="3">3.1.1.17</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">gnl_2</name>
        <name evidence="3" type="ORF">Mal33_45790</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.1.17" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004341">
        <property type="term" value="F:gluconolactonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013658">
        <property type="entry name" value="SGL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005511">
        <property type="entry name" value="SMP-30"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08450">
        <property type="entry name" value="SGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01790">
        <property type="entry name" value="SMP30FAMILY"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021773412" evidence="1">
        <location>
            <begin position="25"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="domain" description="SGL" evidence="2">
        <location>
            <begin position="57"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="336" mass="36380" checksum="205B8A334DF6E21C" modified="2019-10-16" version="1" precursor="true">MTFALRSLALAAILFGLAAQPSSAQDSLGRIERLDPALDKLLAKDAKIEVLASGFTWSEGPLWVPEEGGYVLLSDIPRNSIFRWDAKRGVSLFMSPSGYTGNTYYGLEPGANGLALDAKGQVMMCEHGDRRVSVLTRDGGKRTLVDNYQGKRLNSPNDLVLHSSGAIYFTDPPYGMPKRYDDPRRELDFCGVYRLATDGTLTLISKELARPNGIGLSPDEKTLYVAQSDPKQAIWARFALNDDGTAGAMSILYDATDQVGKLPGLPDGLAVDPQGNLWASGPGGIYVFEPSGKLIGRLLIGRLLTGQRTSNCTLGGPDGKDLYITADSYLCRVRLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZQ9</accession>
    <name>A0A518IZQ9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Outer membrane biogenesis protein BamB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_45380</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018391">
        <property type="entry name" value="PQQ_beta_propeller_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002372">
        <property type="entry name" value="PQQ_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13360">
        <property type="entry name" value="PQQ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00564">
        <property type="entry name" value="PQQ"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021928484" evidence="1">
        <location>
            <begin position="21"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="424" mass="45779" checksum="1434B55A7584BA58" modified="2019-10-16" version="1" precursor="true">MKKIVLSIATLFAISSLVIAEDWPQWRGQARDGKSSETGLFSSWGEDGPPSVWTAEGLGEGYASVSVVDGTIYTTGNFEDGQAVVAIDANSGKRLWKQSVTKSEPKHSYEGSRSTPSVDGDRLYVVSSDGAIVCLDRADGSIRWQREFSDWKGKMMSSWGFSESPLVDGERVLCTPGGPQGLVVALNKMNGEEIWRSQLEASDDDSLKDGAGYSSIMISNGGGVKQYVQLVGRGLVGIRASDGKQLWRYARVGNTTANIPTPLIDGDQVFTSTAYGTGSALLKLKSDGAGGVDAEEIYWLEANQLQNKHGGMILIDGHIYCGTGNGNGLPICVEMKTGEIAWGPERGKGKGETSLVYADDHIVMRRDDGTVMLLRATPEKMDVLNSFKPAFQQGKSWSHPVISGGRLYLREQDKLMCFNLVKGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZV1</accession>
    <name>A0A518IZV1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_46450</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022187106" evidence="1">
        <location>
            <begin position="22"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="290" mass="32527" checksum="12043BE235D30473" modified="2019-10-16" version="1" precursor="true">MKRFGCILLLLFLSGPVAAQAFVPNLGPDLPSITVRCGEVTLKLRRHSQWTPARIDFRGTPMTTERSAYGTVFRYPEIGFIGTGHLENEPEELQSLTFYVDGKEVVTPTAELSGETFRFVRESKIRGFRLTNVFEIKEDRLYETTTVAADVETPLDLVYHFMHAWTPTVSVLMAGSDAKPEADLIQPLLNDDAVHHKFYINAAVDWMSVYEPGSQQFAVSRLLETPATAGSTSKVWNVVGTYRKYYLTAFQNQTVPKGFKGTWRMVTGFGEGDREQWPAAARTLASELSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IZY9</accession>
    <name>A0A518IZY9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Response regulator protein VraR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">vraR_2</name>
        <name evidence="5" type="ORF">Mal33_46850</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
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        <location>
            <begin position="4"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="143"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV58661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="210" mass="22978" checksum="A29016189F432B74" modified="2019-10-16" version="1">MNIKLLVVDDHEVVRLGLRNLLTDVEVEIVGEAVSSAEALEFLTKQTPDIVLLDIRMQGGDGLAALGRIKLDYPELPVVLLSAYDNPTYVARAVALGAAGYLLKDCDRTKLVEAIRLCAGGGSAWTRDELRRVTGALATPRIASDIDVPLTQRESEVLRQMALGLTNKEIAKALDISYETVKEHVQHILRKVGVTDRTQAAVWAVRKNLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J001</accession>
    <name>A0A518J001_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_46950</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005079">
        <property type="entry name" value="Peptidase_C45"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03417">
        <property type="entry name" value="AAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022158321" evidence="1">
        <location>
            <begin position="28"/>
            <end position="615"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="615" mass="66944" checksum="8A5476B5318ED8E9" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J012</accession>
    <name>A0A518J012_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Sulfate transport system permease protein CysW</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">cysW</name>
        <name evidence="6" type="ORF">Mal33_47080</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="14"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="56"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="99"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="151"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="257"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="60"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV58684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="285" mass="31271" checksum="2C0CAA3653C67658" modified="2019-10-16" version="1">MTLQRSPVRRLRDVVFYLIVAGLSANFVLLIVLLLAADLMFTSPAEIVKALQKPEIRGAFGLTLSTCTITAVLSVWVATPLGYALSRYRFPGRSVVDTIVDIPIVLPPLVLGLSLLILFHQPFPFSQWLFPDSNWQLETWLRDRVGFPVTFRWPAVILAQFAVACAFAVRTMRVTFDQIDPRAEDVARTLGCTRGQAFMHVALPQAWRGVIAAGTIAWARALGEFGPILVFAGSTRFRTEVLSTTVFLELSVGQLDAAVAVSLLMVAMAIVVLVTLRWLGAGLST</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J035</accession>
    <name>A0A518J035_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_47160</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011446">
        <property type="entry name" value="BBP7"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07585">
        <property type="entry name" value="BBP7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021807208" evidence="2">
        <location>
            <begin position="23"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="490" mass="52246" checksum="9267A61439597DDC" modified="2019-10-16" version="1" precursor="true">MKRTNIWLTVVAVLAGTVSAWAGEPGQAKGYKNSIGYTNYVGDLSETPHAHAHAPSVPVPAAAPSQPQHSASYGSQGFTTSCDTACDELYDDGCDSIGRRRYLSGLFGRQSARQGSGRTWGRVEALLWWAEDRDSPALISTNPDFGTRPVVPDVGNAGTSVLFGGQNGIESDMMIGNRIDFGSYLDNDHTYGIGGRVYGLWSGGDSVSVSSNGSGPSYGVPFFDVAAVPPLGPGLGVAIGTFGLLPIGQDLGGGQVVTGNVSATSELDFIGSEVYARALMARTADFRVDLIGGYTFHSLDDSIILQGRSILNNTVAGNLSPQNIYDFRDAFDAENTFHGGQIGFETQVVKGRFMFSSLTKVHLGNMNQRVRISGNSQYETVGGGVLTSGDRGLLVQGNGGVYERDTFTFAPEANVKLGYRVCKCATFNVGYSLMMWSDVALAGNHIDNRIDSTRTEAGLNSPTRTNVPNFEFDTDSFFLHGLDLGLTFTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J051</accession>
    <name>A0A518J051_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transcriptional regulator PerR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">perR</name>
        <name evidence="1" type="ORF">Mal33_47430</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002481">
        <property type="entry name" value="FUR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33202">
        <property type="entry name" value="PTHR33202"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01475">
        <property type="entry name" value="FUR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV58718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="143" mass="15683" checksum="095AEB96A7DA0EAC" modified="2019-10-16" version="1">MSQHDESLDLVKQAIRDAGLRATPARIATLQLLRRSSQPLTHSAVVEGLADVNVDKATVFRSLNDMAEVRLVRRTQVGDHVWRFEAIDPNDEHDTGHPHFLCVDCGTVSCLSDVKLTAGSQRASEAVGEVTQILLQGHCNDCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0B7</accession>
    <name>A0A518J0B7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RNA polymerase sigma factor RpoD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rpoD</name>
        <name evidence="7" type="ORF">Mal33_48050</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000943">
        <property type="entry name" value="RNA_pol_sigma70"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007630">
        <property type="entry name" value="RNA_pol_sigma70_r4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04545">
        <property type="entry name" value="Sigma70_r4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00046">
        <property type="entry name" value="SIGMA70FCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="5">
        <location>
            <begin position="165"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4" evidence="6">
        <location>
            <begin position="273"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV58780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="340" mass="38897" checksum="146A290DA55B8360" modified="2019-10-16" version="1">MIIALNKFPGFQVATKPLFDWFDSDGIAAIIDQVGDVESLRRAPMSQVNREKQRLLSQEIEFIDNPRFYESGAGERLFDVAIDLQRTSESKRSFGEGLPTHLDRLCTASLLSPENEPLLFERMNFLLCMAEQCRKRLAYTKTVVQEIDRIHWLLALAAWHRDRIIEANLRLVFSIVKKFVNPMNTFDDLLADGMLALIRAVEKFDYSRGFRFSTYATQVVRRNSYQLVVQRQTDDSRLVVGLDEAGIAESGVPREPFMSEQRWHSLRARLGELLDMLDRREKLIIRARFSIGPHSKVQTLQAIASRLGISKERVRQIESRAIAKLQEMAAGAEVPELTGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0B9</accession>
    <name>A0A518J0B9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CAAX amino terminal protease self-immunity</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_48090</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071586">
        <property type="term" value="P:CAAX-box protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003675">
        <property type="entry name" value="Rce1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02517">
        <property type="entry name" value="Rce1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="39"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="84"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="126"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="171"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="225"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="247"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="279"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV58784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="311" mass="33273" checksum="7A70865A9FC4EC91" modified="2019-10-16" version="1">MNDPHDAAPPSSHDTSEVPIDAELVPELTEPTKPRIWTVWMLVAVVIAFSLQVNLVSVVLAQLAVFGTVEAPDNAMMLKLMDSRVGFCLMLIPSQLAILIPPLIAAFASPEPFRQRLGLVRGHWPLWAWLAGGIATPMVGLVTTLVIGPFIESSEHLDQMTDVFRTHANGGFLIATLLMVGGLPAICEEIMFRGYIQTRLAARFPAVAAIAIASIMFAVFHFDPVHVIAVLPIGLWLGFLRHASGSIFPAMLAHGINNTLSVISVMPEQTDALDAPSTLLTLALLGLGIPCLLATAATAYCFTAPTLADEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0W1</accession>
    <name>A0A518J0W1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nickel uptake substrate-specific transmembrane region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_50080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV58983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019613">
        <property type="entry name" value="DUF4198"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10670">
        <property type="entry name" value="DUF4198"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021767573" evidence="1">
        <location>
            <begin position="23"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV58983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="268" mass="29490" checksum="C837323D066250CB" modified="2019-10-16" version="1" precursor="true">MNRKLTCVLTSLFALAQLTASAHDIWTQTNIPVVAPGEIVHVDLCLGNHGNHHRDFKLAGLVSLDWVTADHQLPDGSRVDLLDKMTSTAMAEKEGYWTQPLLVEAPGVHCIAVQLDRVMQHGKSVRGVRTAKSYFLASHSIDDAKIVGHDHKKPLGMPFEVVLQTCPFTETAVGQPLTVQVLHQGKPKRDVVVSFIPQGAELQGEFDPDFQFRTDSGGLATFVPKAGNRYLIVAHHTADDEKSDEYEFTSYAATVTLHVPVRRPLATQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J0Y7</accession>
    <name>A0A518J0Y7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Calcineurin-like phosphoesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_50310</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021995524" evidence="2">
        <location>
            <begin position="21"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="domain" description="Metallophos" evidence="3">
        <location>
            <begin position="56"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV59006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="369" mass="42238" checksum="286B53F412F872D8" modified="2019-10-16" version="1" precursor="true">MKRWILLGLVLLLLSCYSYASLSGQDRELDAPPGHASKSTPQANETSERDSDSFTLIVLPDTQGYADVRHKETQKHWPDIGDQRSCFFQQTEWIKQNKQKLNIAMAVHVGDITQTDHDAEWKIADTAFKVLDDHVPYVVCSGNHDMGYLPQNRGTSHSRDSRFNAYFGPARFINNPLYRPHFGVDAKQHFRKEGEIESYYLFLNAGGMKFLLITLEFKPRDESLAWANRVVSQHPDCRTIVVTHAYLTSKPGQRSSTDKYKVQGNSGEEIWKKFVSQHRNIFMVLSGHAMENRLTSKGKHGNLVLQVQADYWYWDIPKIKAGSGFLRIMTFYPGKNKIEVQTYSPVLDEFLTRPKSTYSLDYVMDGSAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J158</accession>
    <name>A0A518J158_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fructosamine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_51040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the fructosamine kinase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016477">
        <property type="entry name" value="Fructo-/Ketosamine-3-kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12149">
        <property type="entry name" value="PTHR12149"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03881">
        <property type="entry name" value="Fructosamin_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006221">
        <property type="entry name" value="Ketosamine-3-kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR006221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="287" mass="32463" checksum="1A8F390D9F47BDAF" modified="2019-10-16" version="1">MSERRGEVVAIRDCRSLSGGSISQAWLVDLLPDGQIVAKINAAHFQTAFELEFQGLDELRAVGAIRVPEPLAVEKVGNRAILVSEAIGRGTPSPDFFKRFGQQLASLHRLSQREPDHRFGYRCDNYLGSARQPNGWCDDWPTFVAKHRLGFQIDWARQQSIGSRDLFPLVQSVIKRLPAMLAEASEPPVLLHGDLWSGNYLCDSDGQPVILDPAVYYGHREAELGMLLWMGNCPNEFYEAYNKCWPLRSGWRERAEVYTLYHQLNHLNLFGAGYLSCCEATARRLLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1E9</accession>
    <name>A0A518J1E9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alcohol dehydrogenase</fullName>
            <ecNumber evidence="4">1.1.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Mal33_51760</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.1" evidence="4"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004022">
        <property type="term" value="F:alcohol dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="PKS_ER" evidence="3">
        <location>
            <begin position="10"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV59148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="347" mass="36444" checksum="547E407CCA150300" modified="2019-10-16" version="1">MKAAIYSEFGGPISIETVPDPTPTKRGVVIRVEATGLCRSDWHGWMGHDPDIRLPHVPGHELAGVIEAVGSDVGSWRVGQRVTLPFVCGCGSCPQCSAGHQQVCDRQFQPGFTHWGSFAQYVAIDYADANLVAIPETIDFATAASLGCRFATAFRAIVDQGQVRAGQWVAVHGSGGVGLSATMIASALGASVIAIDIDDQKLDFARTVGAVATVNAQNTEDVVAEIQAITGGGADLSIDALGSPTTCFNSVACLRKRGKHVQVGLMLADHQHPPVPMGKVIAGELEILGSHGMQAHRYPAMLAMIAAGKLKPEKLIGTRIPLSDAVTALPAMNRHQGTGVTIIDRFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J1M7</accession>
    <name>A0A518J1M7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyltransferase EpsD</fullName>
            <ecNumber evidence="3">2.4.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">epsD_2</name>
        <name evidence="3" type="ORF">Mal33_52720</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.4.-.-" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="15"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="177"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV59244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="368" mass="40659" checksum="2DC0DE659513D7AD" modified="2019-10-16" version="1">MTQRICHIIPTLVRGGAEKQLALLASGLPRDRFDVHVVVLTHDGPLRENLEAAGIEVTVVGKRFKADPSAYFRLKRTLKKLSPDLVHTWLFAANSYGRAAARSLGVRRIVAGERCVDQWKTTRHFVIDRALAKRTDAIVTNSSGVRDFYAAHGIDPDLFRVIPNGIPPRTASTITREEACQRLGIDPKRRLIVAVGRLWPQKRLRDLIWAAQLMESARNDSTFVVIGDGPQMGELQRFRDSVTTGQAVTFAGARDDVAELLPHFDLFWIGSGYEGQSNALIEAMQAGLPVVASDIPGNRDLIENGVTGMLAPVGESAEFAKHAYQLLFTDTERAARLGQAGQDRIASDFTVAQMIDRHVDLYSELLDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J229</accession>
    <name>A0A518J229_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_54300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV59395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="302" mass="33596" checksum="1C229400C883A954" modified="2019-10-16" version="1">MSFDVRNRNVSSLLAGLLAVAAIHCSGCRVLAPVPIPVESQQMAPELVDSKSPQVEIGRPQPIIDGIGWVVGIPDKILLWDRRIDRHKISEETIDSTVDYLQANNLPHIKVRANQYNPLDDWHRLTQNKTVAWPWRYSLGALSVAGETIFPGRIIGGDHFNPFTQTIHLYSDVPAVALHEAAHAKDFTRRTYQGTYAAAYLFVPLWHETLASQDVFAFLEEREDRAGLVEANRILYPAYGTYVGSTVGNFFPAYSAPLYYTGVIAGHINGRMLNRELEQQMPAGLVAVNEPVASQPSETESF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J235</accession>
    <name>A0A518J235_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cbb3-type cytochrome c oxidase subunit CcoP2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ccoP2</name>
        <name evidence="9" type="ORF">Mal33_54260</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.280.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032858">
        <property type="entry name" value="CcoP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038414">
        <property type="entry name" value="CcoP_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008168">
        <property type="entry name" value="Cyt_C_IC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13442">
        <property type="entry name" value="Cytochrome_CBB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14715">
        <property type="entry name" value="FixP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00605">
        <property type="entry name" value="CYTCHROMECIC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0349">Heme</keyword>
    <keyword evidence="3 5" id="KW-0408">Iron</keyword>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="25"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="8">
        <location>
            <begin position="90"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="171"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="184"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV59391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="200" mass="22428" checksum="0BF24912D2F57671" modified="2019-10-16" version="1">MTDNNHKLDHSYDGIEEYDNPLPGWWKWLFVASIAFSPMYWVFYHGGAEGRSVHDIYDVALAENTRLQFAEIGDLEPNAETIVRYSHKKNWVRVGEVIFKTNCISCHGRNGEGMVGPNLTDEYFKYIQNVEDIAKVVTNGAGGNAMPAWKTRLHPNEIVLVSAYVASLRGENVEGGKGPDGREIPPWPEAPPEPEKEATP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J261</accession>
    <name>A0A518J261_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Co-chaperonin GroES</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">10 kDa chaperonin</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Chaperonin-10</fullName>
            <shortName evidence="3">Cpn10</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">groS_2</name>
        <name evidence="3" type="synonym">groES</name>
        <name evidence="3" type="synonym">groS</name>
        <name evidence="5" type="ORF">Mal33_54580</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 4">Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3 4">Belongs to the GroES chaperonin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00320">
        <property type="entry name" value="cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.33.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00580">
        <property type="entry name" value="CH10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020818">
        <property type="entry name" value="Chaperonin_GroES"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037124">
        <property type="entry name" value="Chaperonin_GroES_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018369">
        <property type="entry name" value="Chaprnonin_Cpn10_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10772">
        <property type="entry name" value="PTHR10772"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00166">
        <property type="entry name" value="Cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00297">
        <property type="entry name" value="CHAPERONIN10"/>
    </dbReference>
    <dbReference type="SMART" id="SM00883">
        <property type="entry name" value="Cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00681">
        <property type="entry name" value="CHAPERONINS_CPN10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00580"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV59423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="106" mass="11162" checksum="CEB3DD90FC72CD5C" modified="2019-10-16" version="1">MAAATKSKTKIGLQPLGDRLVVQREESEETTAGGIVLPGSAQEKPARGTVVALGDGKLLDDGTRAASQVAVGDRVIFSSYAGETVETQDQEYLLMREDDILAVIEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J282</accession>
    <name>A0A518J282_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_54780</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="238" mass="26783" checksum="FD68D59AAA467703" modified="2019-10-16" version="1">MNKSYRKPATALLLVAIATTVLWTTGASLAQRGEGRRPPRPGGGEKPEIEDTLRLNVYADNWFSLYINGELVAVDSIRFMPHNVISVDVFPKYPMTLAVIAKDNADAKTGMEYNNTQIGDGGFILKLADGTVTGPHWKAKSVSYGPIDRDTRNPRVVHEELPENWFAIDFDDSSWQAAKVYDEQTVRPKRPFYQYDFEGAKFIWADDLELDNTVLFRLTVDSPPDGSQPKRFPILESN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518J2B1</accession>
    <name>A0A518J2B1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_55090</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV59474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV59474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="93" mass="9952" checksum="2D292742DDAC1247" modified="2019-10-16" version="1">MTTTLATVANGVKLRKVDAPAVAEDAETEDTEPDDSKTGDSKTDDSKTDDSKTDDSKTDDSKTDDSKTDGTKTRDIKTDDIKTDDTESSEASE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IM06</accession>
    <name>A0A518IM06_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Polysaccharide pyruvyl transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_00590</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007345">
        <property type="entry name" value="Polysacch_pyruvyl_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04230">
        <property type="entry name" value="PS_pyruv_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021917460" evidence="1">
        <location>
            <begin position="26"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="domain" description="PS_pyruv_trans" evidence="2">
        <location>
            <begin position="49"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="427" mass="47592" checksum="4EF3ED0FD3859BFC" modified="2019-10-16" version="1" precursor="true">MNNNLFNRRDALAMLGLATAGAAMAADDSAAPTNAKKKILLRSSWQTVNIGDIAHTPGVLQILRTHMPDAEITLWPSRVDNGVEELLRAEFPKLKIIKTAAQRKQAFEECEFLLHGSGPSLVAQKDVIRWRDETQKPYGVYGITLPSKGSASTKPTTEPAMAKTIEVLSGAEFVFFRDSHSLALAKEKGCQSKIMEFGPDGAFACDLREPEKANAFLKENDLQPGKFLCCIPRLRYTPYWTIKDRPFDEVKHARNEAMKEHDHAQLRRAIVEVVKTTDLKVLVCPEDQTQMKVGKELLVDPLPAEICKRVVWRPNYWLTGEAVSTYVQSAGLFGNEMHSPIMCIGHGIPAIVCRWAEQTSKGYMWEDIGLGQWLFDLDNPADMPKIVPAVLEMAQNPDKAKQIAAAGRKVVERRQAETMAVLKRSLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IM45</accession>
    <name>A0A518IM45_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Endonuclease/Exonuclease/phosphatase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Mal33_00970</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNase I family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004536">
        <property type="term" value="F:deoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006308">
        <property type="term" value="P:DNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016202">
        <property type="entry name" value="DNase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00130">
        <property type="entry name" value="DNASEI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00476">
        <property type="entry name" value="DNaseIc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="SSF56219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2 6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="6" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="domain" description="Endo/exonuclease/phosphatase" evidence="5">
        <location>
            <begin position="82"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV54151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="346" mass="38380" checksum="C081624A0E2CE54A" modified="2019-10-16" version="1">MATRRKKISSLPIGRFIGPPLTIVLFLVVGYLAMTGRLPFLNGASDQAATTEAGLLPGTEGGLQLTSSGDPAAKPIETLTVATFNIQVFGVKKAEDLEVMRYLALILRQFDVIAVQEIRSMERAPVDQLLELINSTGEQYKVILSERLGRTDSKEQYAYFWDSRRIQFVEGSSYLVNDSADFMHREPFVASFHALQAGVPGAKPFSFTMINVHTDPDETDQELNVLDDVFQSVRAYEFSEDDFILAGDLNVEIDKLGELGQIQSVESVNREQTNTAGSRSIDHLLIDRTATTEFRGAGVINYERDLKLPRELADRISDHRPVWAVFDSSEHAPQGVIAALPETVSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMF2</accession>
    <name>A0A518IMF2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Signal recognition particle receptor FtsY</fullName>
            <shortName evidence="5">SRP receptor</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">ftsY</name>
        <name evidence="7" type="ORF">Mal33_02190</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Peripheral membrane protein</topology>
            <orientation evidence="5">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the GTP-binding SRP family. FtsY subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031226">
        <property type="term" value="C:intrinsic component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006614">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00920">
        <property type="entry name" value="FtsY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013822">
        <property type="entry name" value="Signal_recog_particl_SRP54_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004390">
        <property type="entry name" value="SR_rcpt_FtsY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036225">
        <property type="entry name" value="SRP/SRP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000897">
        <property type="entry name" value="SRP54_GTPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042101">
        <property type="entry name" value="SRP54_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43134:SF7">
        <property type="entry name" value="PTHR43134:SF7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00448">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00962">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00963">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47364">
        <property type="entry name" value="SSF47364"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00064">
        <property type="entry name" value="ftsY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00300">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 5 7" id="KW-0675">Receptor</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SRP54" evidence="6">
        <location>
            <begin position="292"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="125"/>
            <end position="132"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="207"/>
            <end position="211"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="271"/>
            <end position="274"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QDV54269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="326" mass="35099" checksum="F07200A1CA648775" modified="2019-10-16" version="1">MAFWSKKKADDPDTSQAGLFDKFRKSLTKTSQVLNTDIRDLFKNEGRLVEDDFLSELFARLVRTDMGAGPAGRIRDDVATKFRGRKVEMEDILATIRDQVEAMLTQESAELSMADEGPTVILVVGVNGSGKTTSIAKLANRLTQEGNRVVLGAGDTFRAAAVEQLTIWSQRIGCEIVTGKPESDPASVAFATVQKAVDENFDVAIVDTAGRLQTQTHLMQQLDKIRRVIGKPVPSAPHEVLLVLDATAGQNAISQARGFSEAAGCTGIVLSKLDGSAKGGVVIPIREQFELPVKFIGLGEGIDDMAAFDAPMFSQALFSDSLGKPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMH6</accession>
    <name>A0A518IMH6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Formate dehydrogenase H</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">fdhF</name>
        <name evidence="4" type="ORF">Mal33_02410</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008863">
        <property type="term" value="F:formate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030151">
        <property type="term" value="F:molybdenum ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043546">
        <property type="term" value="F:molybdopterin cofactor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02787">
        <property type="entry name" value="MopB_CT_ydeP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009010">
        <property type="entry name" value="Asp_de-COase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037951">
        <property type="entry name" value="MopB_CT_YdeP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006657">
        <property type="entry name" value="MoPterin_dinucl-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006656">
        <property type="entry name" value="Mopterin_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010046">
        <property type="entry name" value="Mopterin_OxRdtse_a_bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43105:SF4">
        <property type="entry name" value="PTHR43105:SF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00384">
        <property type="entry name" value="Molybdopterin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01568">
        <property type="entry name" value="Molydop_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50692">
        <property type="entry name" value="SSF50692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01701">
        <property type="entry name" value="Fdhalpha-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Molybdopterin" evidence="2">
        <location>
            <begin position="104"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="domain" description="Molydop_binding" evidence="3">
        <location>
            <begin position="618"/>
            <end position="718"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV54291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="727" mass="80276" checksum="5AF35A6600010506" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IML0</accession>
    <name>A0A518IML0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_02810</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="113" mass="11789" checksum="4BFF93CAE94FAA95" modified="2019-10-16" version="1">MCEARPVGHAVKREGVAAIGSLRLTAVATPRASSVGAMCEARPAGHAVKREGVVAIGSFRLTAVATPRALSVGVMCEARPVGHAVKRVGCCRYRFASFNRGGNAPRVECWGDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IMQ5</accession>
    <name>A0A518IMQ5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">30S ribosomal protein S4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6 9" type="primary">rpsD</name>
        <name evidence="9" type="ORF">Mal33_03220</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.</text>
    </comment>
    <comment type="function">
        <text evidence="6">With S5 and S12 plays an important role in translational accuracy.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the universal ribosomal protein uS4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01306_B">
        <property type="entry name" value="Ribosomal_S4_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022801">
        <property type="entry name" value="Ribosomal_S4/S9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001912">
        <property type="entry name" value="Ribosomal_S4/S9_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005709">
        <property type="entry name" value="Ribosomal_S4_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11831">
        <property type="entry name" value="PTHR11831"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11831:SF4">
        <property type="entry name" value="PTHR11831:SF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00163">
        <property type="entry name" value="Ribosomal_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01390">
        <property type="entry name" value="Ribosomal_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01017">
        <property type="entry name" value="rpsD_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 6" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_S4" evidence="8">
        <location>
            <begin position="3"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="S4" evidence="7">
        <location>
            <begin position="93"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV54368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="202" mass="22682" checksum="E67C1B403085ACA4" modified="2019-10-16" version="1">MARYTGPKARINRRLGAMIYETAGAARAMERRNTPPGMHTRGRRPSNYGLALMEKQKIKHYYGLGERQLRRYFDAVSSKQGNTGELLLLMCERRLDNIVRRCGFTKTRPQARQGVTHGHFLVNGVKVTKPNYLLRPGDVVEVRDREGLKNLYRGVIANASPDALDWVAFDSENLKATVQGLPGPSDISLPVDANSVVEFLSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IN35</accession>
    <name>A0A518IN35_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE</fullName>
            <ecNumber evidence="3">2.1.1.163</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ubiE_1</name>
        <name evidence="3" type="ORF">Mal33_04530</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.1.1.163" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043770">
        <property type="term" value="F:demethylmenaquinone methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102094">
        <property type="term" value="F:S-adenosylmethionine:2-demethylmenaquinol methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102955">
        <property type="term" value="F:S-adenosylmethionine:2-demethylmenaquinol-7 methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102027">
        <property type="term" value="F:S-adenosylmethionine:2-demethylquinol-8 methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026669">
        <property type="entry name" value="Arsenite_MeTrfase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43675">
        <property type="entry name" value="PTHR43675"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0830">Ubiquinone</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022196598" evidence="1">
        <location>
            <begin position="24"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="Methyltransf_11" evidence="2">
        <location>
            <begin position="90"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV54499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="246" mass="27379" checksum="EDAFB25478249FD9" modified="2019-10-16" version="1" precursor="true">MTHRSFLHISLAVMFAISLQTVARLEAQQTTTEAPATIPLPAGINDNFKDPELNVSEWLARFEVESREVYAGRKAVLEACAIKPGERIADVGAGTGFYSQLFAKTTGWDGWVYSVDIAPNFLQHIASRATADGIENLTTVLGTDVSIRLPPESVDLVFICDTYHHFEKPMQSLASIYRALKPGGRLVLIDFDRIPGKSREFILGHVRAGKEVFQSEVIAAGFQFTDEVEVDAFEENYLLRFTKPRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IN37</accession>
    <name>A0A518IN37_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Multidrug resistance protein MdtC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">mdtC_2</name>
        <name evidence="2" type="ORF">Mal33_04590</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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            <end position="1045"/>
        </location>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="QDV54505.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
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    <sequence length="1065" mass="115199" checksum="5A6F353BDAC4BE89" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IN60</accession>
    <name>A0A518IN60_9BACT</name>
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        <submittedName>
            <fullName evidence="6">Colicin V production protein</fullName>
        </submittedName>
    </protein>
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        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
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        <source>
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        </source>
    </evidence>
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        <source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="QDV54526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="221" mass="24542" checksum="6F4B8DE3539DFD1E" modified="2019-10-16" version="1">MLIALAAATILGAIKGFAWQVASLASISLSYWVAMRFREPFSQQIHAEPPWNMFLAMFILFTGTMIAIWILFRMLSRTIDRLRLRTFDHQLGGILGLAKGVIYCILITMFALSLLGDSVRTQIVQSRSGYYIAKLLSYSDKVIPAELQEIVGPYLDRLDEQLRADGNASTGPAQPLPWGNNESTAGAIVDAVQQNLQPPNDSENLIPAELLTPKFFDQIQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
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    <name>A0A518IN97_9BACT</name>
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        <submittedName>
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        <name evidence="6" type="primary">prc</name>
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        <lineage>
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        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the peptidase S41A family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.102" evidence="6"/>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Peptidase_S41A"/>
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    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="TSPc"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="2 3" id="KW-0720">Serine protease</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021751927" evidence="4">
        <location>
            <begin position="27"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="5">
        <location>
            <begin position="260"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV54551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="708" mass="79558" checksum="476B57C38138FB71" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IN99</accession>
    <name>A0A518IN99_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">6-N-hydroxylaminopurine resistance protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_05150</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
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            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030151">
        <property type="term" value="F:molybdenum ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005302">
        <property type="entry name" value="MoCF_Sase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011037">
        <property type="entry name" value="Pyrv_Knase-like_insert_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005163">
        <property type="entry name" value="YiiM-like_3-alpha_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03475">
        <property type="entry name" value="3-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03473">
        <property type="entry name" value="MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50800">
        <property type="entry name" value="SSF50800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51340">
        <property type="entry name" value="MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MOSC" evidence="1">
        <location>
            <begin position="33"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="232" mass="25773" checksum="358E466329EDA42B" modified="2019-10-16" version="1">MNGTRQAELLSVQVGLPRTITADKEWTTGFWKEPIREPLWLGTTNLQGDGQADLVNHGGPHKAVCVYSAAHFPVWRETLGIDDLGAGAFGENFTVSDLTEADVCIGDVWSVGDAVVQVSQPRQPCWKLAKRWGIKDLAYQVQQTGRTGWYFRVLEEGLVGPGMPVRLMQRQWDDWTIAAANHLMHHDKQNIDQAARLAAVPTLSPNWQATLNKRIAKQPKVDESLRLDGPGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INL2</accession>
    <name>A0A518INL2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Oxoglutarate dehydrogenase (succinyl-transferring)</fullName>
            <ecNumber evidence="2">1.2.4.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">sucA</name>
        <name evidence="6" type="ORF">Mal33_06250</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="1.2.4.2" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004591">
        <property type="term" value="F:oxoglutarate dehydrogenase (succinyl-transferring) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11610">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032106">
        <property type="entry name" value="2-oxogl_dehyd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011603">
        <property type="entry name" value="2oxoglutarate_DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001017">
        <property type="entry name" value="DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031717">
        <property type="entry name" value="KGD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042179">
        <property type="entry name" value="KGD_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23152">
        <property type="entry name" value="PTHR23152"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16078">
        <property type="entry name" value="2-oxogl_dehyd_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00676">
        <property type="entry name" value="E1_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16870">
        <property type="entry name" value="OxoGdeHyase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000157">
        <property type="entry name" value="Oxoglu_dh_E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00239">
        <property type="entry name" value="2oxo_dh_E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="Transket_pyr" evidence="5">
        <location>
            <begin position="582"/>
            <end position="775"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV54670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="923" mass="105393" checksum="EBA35DA01B7508D1" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518INT5</accession>
    <name>A0A518INT5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_07050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV54745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="153" mass="17182" checksum="736AE9C11B5FCDB2" modified="2019-10-16" version="1">MSNPHRPVSPIFSIDVSAEPPTPASPQFDGDEQVIELLRELVVGQQKQNQLLEQMTQQTAAMQKQRSNELQQWKDANPLLSKHCHRAAETLSRVQTQFLENLTVEVLDNAEHLVDGEFMLNEFVDRFGPRMAHLNGVLQVLAQLGTGQPTSET</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IP92</accession>
    <name>A0A518IP92_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_08760</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="169" mass="18268" checksum="D491921F5C112B9E" modified="2019-10-16" version="1">MPVTHRIPLEGLTAPWNASAATEGVGIVKWNANSSPLRKLAVAPLLCCGFVFAMHQERAFASCGDYLQMPEEHSTMSTTGADLLHSPPFEFPPLPKRCHGPGCSQLPDMPLSDFAQSPKLISLKVFAVLGCATVDEPKLPAINDGLQHSESFRLSSDIFRPPRSAFGHC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPA0</accession>
    <name>A0A518IPA0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_08740</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV54908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV54908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="154" mass="17087" checksum="9EFBB1F022FC3B24" modified="2019-10-16" version="1">MHFCQKHSLLSTSKTNETPWLQLQLMRRLTWAVLLIGSVIASIGCSGYSPAEHRVDTNVAHDTLQRVLSQWQQGRSSEDCLAMQPPVIVQDMDWKSGTQLDAFEIVAPGEARDANYYCEVTLSLHSSDSPPRSKKVVYLVGTSPVLTVFRSAAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IPQ1</accession>
    <name>A0A518IPQ1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">dTDP-3-amino-3,4, 6-trideoxy-alpha-D-glucopyranose</fullName>
            <ecNumber evidence="2">2.1.1.234</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">desVI</name>
        <name evidence="2" type="ORF">Mal33_10200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.1.1.234" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_25" evidence="1">
        <location>
            <begin position="49"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="260" mass="29606" checksum="A0315504B37601A6" modified="2019-10-16" version="1">MDVVNESIYDHPKYYDLVFGADCAAEMGFIRDINDVYLGGKARRLFEPACGTGRLLYGLAKHDFEVSGIDLNPKAVEFCNKRFERKGMKPTAWVADMSDFKPKRKWDLAFNTINSFRHLTTAQTAHDHMRCMAAGTKKGGIYLVGIHLTPTAAAPSEEESWAARRGHLSIVTQMWTIERAPRKRMERFGIRFDIFTPKGQKRIADELRLRSYTPKQFQSLIDTEGSWEIAGTYDFGYDVSEPITVDASCEDVVYVLRKRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQ05</accession>
    <name>A0A518IQ05_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_11330</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025409">
        <property type="entry name" value="DUF4303"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14136">
        <property type="entry name" value="DUF4303"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="183" mass="21164" checksum="B35E564B3DF82E10" modified="2019-10-16" version="1">MQTELRSDLDDWKKSFRDELSSHLATLVLDQDIYGFAIEPSEDLSSMHFITCVGRESNLKGEVSGSRAWLDRRYCHVEWDGYLPPSDFGGSLERLNAISEKYHNLLIDSDTCEFTEDGNEFRDTWYAEILAVMIELDKNGSFGKIWFKIISFSDFDHPIQKESFTRLNRDRALNDAESLFDIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQ39</accession>
    <name>A0A518IQ39_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Undecaprenyl phosphate N,N'-diacetylbacillosamine 1-phosphate transferase</fullName>
            <ecNumber evidence="3">2.7.8.36</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">pglC</name>
        <name evidence="3" type="ORF">Mal33_11780</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial sugar transferase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.36" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102334">
        <property type="term" value="F:N,N'-diacetylbacilliosaminyl-1-phosphate transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003362">
        <property type="entry name" value="Bact_transf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02397">
        <property type="entry name" value="Bac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Bac_transf" evidence="2">
        <location>
            <begin position="2"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="208" mass="23227" checksum="B5D316D0C9FB2AAD" modified="2019-10-16" version="1">MKRAFDLCAAAAGLICIGPLMFSIAVLVRLTSRGNAIHWSKRVGARNILFAMPKFRTMYQDTPQLATHLLQDANSHITPLGRILRKTSLDELPQLWSVLVGDMSFVGPRPALYNQHDLVELRTQTEVHQLAPGITGWAQINGRDELSVSDKVDFDVEYLRRQSFYFDLKILVLTLVKVVRRDGICQAETPQTVALSLPSVDAQSNRAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQA0</accession>
    <name>A0A518IQA0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Prenyltransferase and squalene oxidase repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_12460</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001330">
        <property type="entry name" value="PFTB_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008930">
        <property type="entry name" value="Terpenoid_cyclase/PrenylTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00432">
        <property type="entry name" value="Prenyltrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48239">
        <property type="entry name" value="SSF48239"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="355" mass="38928" checksum="81432AD21F53B4FE" modified="2019-10-16" version="1">MTNNLARTGTISRRDLIGRSIGLLTASALPAAAVAQTGDDGLYTPTVSLAIDRGLASLVARQTADGSFGDGRGTGLGRNVAVVSLAGLAMLSRGSLPDRGPHGAALDRCVDYIADACEDETGFIIRRESVSRGAMYGHGFATLFLAEVYGTSDRKDLQRKLNHAVDLIVRSQNSEGGWRYEPEPRDADLSVTICQMMALRAARNAGTFVPGETIERAVDYVRRCQNPDGGFMYQLTGGESRFPLTAGAIVALQNAGRYRGKELDDGYDFLSNRAGHNFSPQRNNYFFYAHYYSVQALWQRGGPEWKAWYEQLRDILLSAQLNDGSWLDYTDRTYATAMACIILNTPRSLLPIFQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQB5</accession>
    <name>A0A518IQB5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">23S rRNA (Uridine(2479)-2'-O)-methyltransferase</fullName>
            <ecNumber evidence="2">2.1.1.208</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">aviRb</name>
        <name evidence="2" type="ORF">Mal33_12610</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.1.1.208" evidence="2"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="L30e-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="SSF55315"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SpoU_methylase" evidence="1">
        <location>
            <begin position="124"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="273" mass="29075" checksum="AFF56EB61C3BD9D5" modified="2019-10-16" version="1">MPLTITSRSNPRYRGWVQLRSRRARKRSGEFLIDGARDTLRAIQSGILPREILCSADCDLEAVAGESELGQVLAWAEANDALIRVASALFPAVCYGQRDSHVVAVASAASSAPLDGLSVPLAPLIVILDGIEKPGNVGAIYRTADAVGADAVLLTGTTTDRFNPNAIRSSAGTVFAMPTAIGDHDAVAKWLADRKIKVALARVDGECSYWDLPLTEAIAIVFGNEAEGLGTQWERAPHEAFRIPMAGIADSLNVSVSAAVVLFEAKRQRLSKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQB6</accession>
    <name>A0A518IQB6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Exodeoxyribonuclease 7 small subunit</fullName>
            <ecNumber evidence="3">3.1.11.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Exodeoxyribonuclease VII small subunit</fullName>
            <shortName evidence="3">Exonuclease VII small subunit</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 5" type="primary">xseB</name>
        <name evidence="5" type="ORF">Mal33_12580</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield nucleoside 5'-phosphates.</text>
            <dbReference type="EC" id="3.1.11.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Heterooligomer composed of large and small subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the XseB family.</text>
    </comment>
    <dbReference type="EC" id="3.1.11.6" evidence="3"/>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009318">
        <property type="term" value="C:exodeoxyribonuclease VII complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008855">
        <property type="term" value="F:exodeoxyribonuclease VII activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006308">
        <property type="term" value="P:DNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1040">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00337">
        <property type="entry name" value="Exonuc_7_S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003761">
        <property type="entry name" value="Exonuc_VII_S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037004">
        <property type="entry name" value="Exonuc_VII_ssu_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34137">
        <property type="entry name" value="PTHR34137"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02609">
        <property type="entry name" value="Exonuc_VII_S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116842">
        <property type="entry name" value="SSF116842"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01280">
        <property type="entry name" value="xseB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="83"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="11"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="83"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QDV55288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="127" mass="14355" checksum="4CB864BA2EFFC650" modified="2019-10-16" version="1">MKKKSARTKTSETASDNSSDDTPPLQFEEGLSKTQQIVRDLESGDLTLEESLQAYEVGVRTIRHCQELLNSFERRIERLTGFDKEGNPITEPFDESEMTLEEKQQGRGRRRGAAASKKSTDDNANLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQI2</accession>
    <name>A0A518IQI2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Flagellar L-ring protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">flgH</name>
        <name evidence="8" type="ORF">Mal33_12940</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Bacterial flagellum basal body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the FlgH family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009427">
        <property type="term" value="C:bacterial-type flagellum basal body, distal rod, L ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003774">
        <property type="term" value="F:cytoskeletal motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000527">
        <property type="entry name" value="Flag_Lring"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34933">
        <property type="entry name" value="PTHR34933"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02107">
        <property type="entry name" value="FlgH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="8" id="KW-0966">Cell projection</keyword>
    <keyword evidence="8" id="KW-0969">Cilium</keyword>
    <keyword evidence="8" id="KW-0282">Flagellum</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022059005" evidence="7">
        <location>
            <begin position="24"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="33"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QDV55323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="263" mass="29206" checksum="420E5B405213F0EA" modified="2019-10-16" version="1" precursor="true">MLKAFSSTWFVGLLLGCAAVAVAQENPFPQVQSGIGTEDIAPPSNQNSDPYDRGAASDPSRAAPSQAAGAQYTQRYDAPLGLQSASWTYIPPPPTRTLQMNDIVTIRVDEIARVQAEGSASTRKNGLYDTLLKDWINLRGGKLQPDTHEGGDLRLQGTVNSLYRADSEIESREALSFNIAARVVDIRPNGNLVVEAHKTMYVNENVWETFLSGTCRSEDIGPDNVVLSRDLLDLQIRKNDRGRMRDGYKRGWFTRWFETLQPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQI3</accession>
    <name>A0A518IQI3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_13180</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021375">
        <property type="entry name" value="DUF2997"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11211">
        <property type="entry name" value="DUF2997"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="64" mass="6919" checksum="38ACC2E6E4C70D0B" modified="2019-10-16" version="1">MKTIEITIAADGNSRVETKGFTGTSCRDASRFLEASLGATKTEKLTDGFYATNSQIQQETESPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQM4</accession>
    <name>A0A518IQM4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cobalt-zinc-cadmium resistance protein CzcB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">czcB_2</name>
        <name evidence="4" type="ORF">Mal33_13410</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="45"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="HlyD_D23" evidence="3">
        <location>
            <begin position="201"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QDV55370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="559" mass="60575" checksum="C65EBB6BFFEDCB53" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQQ5</accession>
    <name>A0A518IQQ5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Putative membrane protein insertion efficiency factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_13990</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Could be involved in insertion of integral membrane proteins into the membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0161 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00386">
        <property type="entry name" value="UPF0161_YidD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002696">
        <property type="entry name" value="Membr_insert_effic_factor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33383">
        <property type="entry name" value="PTHR33383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01809">
        <property type="entry name" value="YidD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01234">
        <property type="entry name" value="Haemolytic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00278">
        <property type="entry name" value="TIGR00278"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="68" mass="7972" checksum="084AFFE0BAC3EAD6" modified="2019-10-16" version="1">MRWLFILPIRFYQRWISPMLGPNCRFSPTCSQYTIEAIGKYGVLRGICKGVWRIARCHPWNPGGYDPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IQZ3</accession>
    <name>A0A518IQZ3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_14850</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="94" mass="10134" checksum="D28A7065E84AAED6" modified="2019-10-16" version="1">MTADQIFVGSIAIVLSIVTTIAALGYLPAAFELGVAKRIQQRYGQRGAARFYWLVSALLFALGLVILCDVRPSFAVPEAEREQMIAGDSDGESQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IR12</accession>
    <name>A0A518IR12_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Mal33_15080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022075460" evidence="1">
        <location>
            <begin position="25"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="144" mass="15509" checksum="CE1B2E4360946272" modified="2019-10-16" version="1" precursor="true">MTRRSTFTAAMFLLLGSIAIPASAVGYPNLGYFGSYQPYGIQSRTSVATPPYFALHPPVYYGNRHTRPYGISPFASLPQVAAPSTYQGRLAPDFVNPPQQNPYCNSCTTGASTHPASKTTRKNGLVRTNPYAEKSDVSLAGTDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IR15</accession>
    <name>A0A518IR15_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type II secretion system protein G</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">pulG_2</name>
        <name evidence="2" type="ORF">Mal33_15150</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011453">
        <property type="entry name" value="DUF1559"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07596">
        <property type="entry name" value="SBP_bac_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QDV55538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="340" mass="36629" checksum="C487F5C305B3EF75" modified="2019-10-16" version="1">MQKHRTKDGFTLVELLVVIAIIGILVGLLLPAVQAAREAARRMQCSNNLKQLGLALHNYESTYKKFPAGRFSLGGLNKSAPASPYLPDPLAKNGQGLVSLLPFMEQQPLYDQFDHSTAFGNYIRPGGPPLTTPDALASGNAALSEMIVTSFRCPSDSGSETIAVSSYYSPDGGAGVAAQKTNYDFLMPASTLTNYNYHRGVSLSTRYMFGENSYTPISGVQDGTSNTLAMGELTFETFNGDTSAWSYAGWLSVGIDPVGAYNSTFPSRGLNVWNYGNNSSPLNNMRGRRASWYSVASLHPGGCMFVLADGAVRYISETIDTTNLTNLSRMADGQVIDADF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRC6</accession>
    <name>A0A518IRC6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Preprotein translocase subunit YajC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Mal33_16360</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">Mal33</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the YajC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003849">
        <property type="entry name" value="Preprotein_translocase_YajC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33909">
        <property type="entry name" value="PTHR33909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02699">
        <property type="entry name" value="YajC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01853">
        <property type="entry name" value="YAJCTRNLCASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01323">
        <property type="entry name" value="YajC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00739">
        <property type="entry name" value="yajC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="35"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QDV55657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="130" mass="14574" checksum="FD96974BA5BCB7BD" modified="2019-10-16" version="1">MLESQFLTFMVPIGNRIGLLAQDAVPVEGPAWQQILFNPIGMITILVVLFYVMVLLPERRNRNELTKRLAALKKNDRVVTVGGIHGTIVNITESDKVVIRVDENNNTRLHVNRSAVSRVISDDDDKSVKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IRK3</accession>
    <name>A0A518IRK3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_16960</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="233" mass="25925" checksum="E945EBC4A48E0886" modified="2019-10-16" version="1">MWHTSTGDRTLSGSEATLIVQTCVAMIDALEWEIRNDNGAVVCESGVELYDEQMVYQRIALLNEVCHGLLSPAQAMPELTAELEATVMAIFETVKSQIELEIDAGQCFGDSCCDMRSMVLAAFIDNAPGSEADAANIEDDLDDIPDPWCDEIEQWDLVVELLADRILWDRDFEMASMIVDEEPEMAEAYKQVLGIANDYFSMAPPEVNEGDAPACLHKLRSFLNQSALPRRPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IS61</accession>
    <name>A0A518IS61_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Mal33_18990</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QDV55920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="2113" mass="237733" checksum="3017AE3CA0E30D65" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518IS80</accession>
    <name>A0A518IS80_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Mal33_19100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV55931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5021975785" evidence="2">
        <location>
            <begin position="26"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="541"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="239"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="323"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="370"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV55931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="636" mass="71279" checksum="0DD2A94EF5F807FF" modified="2019-10-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISM7</accession>
    <name>A0A518ISM7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Serine-aspartate repeat-containing protein D</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">sdrD_1</name>
        <name evidence="3" type="ORF">Mal33_20800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002105">
        <property type="entry name" value="Dockerin_1_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036439">
        <property type="entry name" value="Dockerin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045474">
        <property type="entry name" value="GEVED"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00404">
        <property type="entry name" value="Dockerin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20009">
        <property type="entry name" value="GEVED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63446">
        <property type="entry name" value="SSF63446"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GEVED" evidence="2">
        <location>
            <begin position="745"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1483"/>
            <end position="1503"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1569"/>
            <end position="1629"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1483"/>
            <end position="1501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1599"/>
            <end position="1619"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QDV56101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="1643" mass="172010" checksum="5A4964D588505837" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISN1</accession>
    <name>A0A518ISN1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cadherin domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Mal33_20770</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">Mal33</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007156">
        <property type="term" value="P:homophilic cell adhesion via plasma membrane adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002126">
        <property type="entry name" value="Cadherin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015919">
        <property type="entry name" value="Cadherin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039005">
        <property type="entry name" value="CSPG_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025592">
        <property type="entry name" value="DUF4347"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00028">
        <property type="entry name" value="Cadherin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14252">
        <property type="entry name" value="DUF4347"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00112">
        <property type="entry name" value="CA"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49313">
        <property type="entry name" value="SSF49313"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50268">
        <property type="entry name" value="CADHERIN_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51854">
        <property type="entry name" value="CSPG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Cadherin" evidence="5">
        <location>
            <begin position="566"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="5">
        <location>
            <begin position="952"/>
            <end position="1045"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="5">
        <location>
            <begin position="1803"/>
            <end position="1906"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="5">
        <location>
            <begin position="1899"/>
            <end position="2009"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1999"/>
            <end position="2053"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QDV56098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000316770"/>
        </source>
    </evidence>
    <sequence length="2229" mass="229209" checksum="BCD8699F001A987D" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2019-10-16" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A518ISR5</accession>
    <name>A0A518ISR5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">L-lysine 2,3-aminomutase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">EF-P post-translational modification enzyme B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">epmB</name>
        <name evidence="14" type="ORF">Mal33_21130</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Rosistilla oblonga</name>
        <dbReference type="NCBI Taxonomy" id="2527990"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Planctomycetes</taxon>
            <taxon>Planctomycetia</taxon>
            <taxon>Pirellulales</taxon>
            <taxon>Pirellulaceae</taxon>
            <taxon>Rosistilla</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2019-02" db="EMBL/GenBank/DDBJ databases">
            <title>Deep-cultivation of Planctomycetes and their phenomic and genomic characterization uncovers novel biology.</title>
            <authorList>
                <person name="Wiegand S."/>
                <person name="Jogler M."/>
                <person name="Boedeker C."/>
                <person name="Pinto D."/>
                <person name="Vollmers J."/>
                <person name="Rivas-Marin E."/>
                <person name="Kohn T."/>
                <person name="Peeters S.H."/>
                <person name="Heuer A."/>
                <person name="Rast P."/>
                <person name="Oberbeckmann S."/>
                <person name="Bunk B."/>
                <person name="Jeske O."/>
                <person name="Meyerdierks A."/>
                <person name="Storesund J.E."/>
                <person name="Kallscheuer N."/>
                <person name="Luecker S."/>
                <person name="Lage O.M."/>
                <person name="Pohl T."/>
                <person name="Merkel B.J."/>
                <person name="Hornburger P."/>
                <person name="Mueller R.-W."/>
                <person name="Bruemmer F."/>
                <person name="Labrenz M."/>
                <person name="Spormann A.M."/>
                <person name="Op den Camp H."/>
                <person name="Overmann J."/>
                <person name="Amann R."/>
                <person name="Jetten M.S.M."/>
                <person name="Mascher T."/>
                <person name="Medema M.H."/>
                <person name="Devos D.P."/>
                <person name="Kaster A.-K."/>
                <person name="Ovreas L."/>
                <person name="Rohde M."/>
                <person name="Galperin M.Y."/>
                <person name="Jogler C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">Mal33</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>L-lysine = D-beta-lysine</text>
            <dbReference type="Rhea" id="RHEA:44148"/>
            <dbReference type="ChEBI" id="CHEBI:32551"/>
            <dbReference type="ChEBI" id="CHEBI:84138"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 12">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the radical SAM superfamily. KamA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP036318">
        <property type="protein sequence ID" value="QDV56134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000316770">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022462">
        <property type="entry name" value="EpmB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003739">
        <property type="entry name" value="Lys_aminomutase/Glu_NH3_mut"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30538">
        <property type="entry name" value="PTHR30538"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004911">
        <property type="entry name" value="DUF160"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00314">
        <property type="entry name" value="L-lysine_2_3-aminomutase_(yjeK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01070">
        <property type="entry name" value="PLP-dependent"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03821">
        <property type="entry name" value="EFP_modif_epmB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00238">
        <property type="entry name" value="TIGR00238"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="8" id="KW-0408">Iron</keyword>
    <keyword evidence="9 11" id="KW-